Pyruvate + Ubiquinone + H2O <=> Acetate + Ubiquinol + CO2
Phosphoramidate + D-Hexose <=> Ammonia + alpha-D-Hexose 1-phosphate
ATP + Myosin light chain <=> ADP + Myosin light chain phosphate
Myosin light chain phosphate + H2O <=> Myosin light chain + Orthophosphate
Acetyl-CoA + (S)-2-Methylmalate <=> Acetate + (3S)-Citramalyl-CoA
Succinyl-CoA + (S)-2-Methylmalate <=> Succinate + (3S)-Citramalyl-CoA
(R)-Pantolactone + NADP+ <=> Dihydro-4,4-dimethyl-2,3-furandione + NADPH + H+
3-Hydroxypropionyl-CoA + Orthophosphate + ADP <=> 3-Hydroxypropanoate + CoA + ATP
3-Hydroxypropanoate + CoA <=> 3-Hydroxypropionyl-CoA + H2O
ATP + L-Fucose <=> ADP + L-Fucose 1-phosphate
alpha-L-Fucoside + H2O <=> Alcohol + L-Fucose
L-Fucose <=> L-Fuculose
Hydroxymethylbilane <=> Uroporphyrinogen III + H2O
Hydroxymethylbilane <=> Uroporphyrinogen I + H2O
Acetyl-CoA + N6-Hydroxy-L-lysine <=> CoA + N6-Acetyl-N6-hydroxy-L-lysine
(S)-3-Methyl-2-oxopentanoic acid + CoA + NAD+ <=> (S)-2-Methylbutanoyl-CoA + CO2 + NADH + H+
(S)-2-Methylbutanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
3beta-Hydroxy-Delta5-steroid + NAD+ <=> 3-Oxo-Delta5-steroid + NADH + H+
4-Guanidinobutanal + NAD+ + H2O <=> 4-Guanidinobutanoate + NADH + H+
5-Guanidino-2-oxopentanoate <=> 4-Guanidinobutanal + CO2
4-Guanidinobutanamide + H2O <=> 4-Guanidinobutanoate + Ammonia
4-Maleylacetoacetate <=> 4-Fumarylacetoacetate
ATP + 7,8-Diaminononanoate + CO2 <=> ADP + Orthophosphate + Dethiobiotin
L-Gulono-1,4-lactone + NADP+ <=> D-Glucuronolactone + NADPH + H+
L-Gulono-1,4-lactone + Oxygen <=> L-xylo-Hexulonolactone + Hydrogen peroxide
2 Monodehydroascorbate <=> Dehydroascorbate + Ascorbate
ATP + N-Methylhydantoin + 2 H2O <=> ADP + Orthophosphate + N-Carbamoylsarcosine
N-Formimino-L-aspartate + H2O <=> N-Formyl-L-aspartate + Ammonia
Folinic acid + L-Glutamate <=> Tetrahydrofolate + N-Formyl-L-glutamate
UDP-glucose + Polyprenyl phosphate <=> UDP + Polyprenylphosphate-glucose
UDP-N-acetylmuramate + NAD+ <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + NADH + H+
UDP-N-acetylmuramate + NADP+ <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + NADPH + H+
ATP + UDP-N-acetylmuramate + L-Alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanine
2 S-Adenosyl-L-methionine + Uroporphyrinogen III <=> 2 S-Adenosyl-L-homocysteine + Precorrin 2
Uroporphyrinogen III <=> Coproporphyrinogen III + 4 CO2
(R)-4-Dehydropantoate + NAD+ + H2O <=> (R)-3,3-Dimethylmalate + NADH + H+
(S)-2,3-Epoxysqualene <=> Lanosterol
(S)-2,3-Epoxysqualene <=> Cycloartenol
(S)-6-Hydroxynicotine + H2O + Oxygen <=> 6-Hydroxypseudooxynicotine + Hydrogen peroxide
2,5-Dihydroxypyridine + Oxygen + H2O <=> Maleamate + Formate
3,5-Diiodo-L-tyrosine + 2-Oxoglutarate <=> 3,5-Diiodo-4-hydroxyphenylpyruvate + L-Glutamate
2 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Thyroxine + Dehydroalanine + 2 H2O
ATP + Pimelate + CoA <=> AMP + Diphosphate + Pimeloyl-CoA
Pimeloyl-CoA + L-Alanine <=> 8-Amino-7-oxononanoate + CoA + CO2
Cyclohexane-1,3-dione + H2O <=> 5-Oxohexanoic acid
UDP-glucose + Phenylacetothiohydroximate <=> UDP + Desulfoglucotropeolin
3'-Phosphoadenylyl sulfate + Desulfoglucotropeolin <=> Adenosine 3',5'-bisphosphate + Glucotropaeolin
N,6-O-Disulfo-D-glucosamine + H2O <=> N-Sulfo-D-glucosamine + Sulfate
O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate
Procollagen L-proline + 2-Oxoglutarate + Oxygen <=> Procollagen trans-3-hydroxy-L-proline + Succinate + CO2
Procollagen L-proline + 2-Oxoglutarate + Oxygen <=> Procollagen trans-4-hydroxy-L-proline + Succinate + CO2
Coproporphyrinogen III + Oxygen <=> Protoporphyrinogen IX + 2 CO2 + 2 H2O
Protoporphyrinogen IX + 3 Oxygen <=> Protoporphyrin + 3 Hydrogen peroxide
4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 4-Methyl-5-(2-phosphooxyethyl)thiazole <=> Diphosphate + Thiamin monophosphate
(3R)-3-Hydroxyacyl-CoA <=> cis-2,3-Dehydroacyl-CoA + H2O
(S)-3-Hydroxybutanoate + 2-Oxoglutarate <=> Acetoacetate + (R)-2-Hydroxyglutarate
16alpha-Hydroxysteroid + NAD+ <=> 16-Oxosteroid + NADH + H+
16alpha-Hydroxysteroid + NADP+ <=> 16-Oxosteroid + NADPH + H+
16alpha-Hydroxysteroid <=> 16beta-Hydroxysteroid
S-Adenosyl-L-methionine + 11-O-Demethyl-17-O-deacetylvindoline <=> S-Adenosyl-L-homocysteine + Deacetylvindoline
Acetyl-CoA + Deacetylvindoline <=> CoA + Vindoline
S-Adenosyl-L-methionine + 8-Amino-7-oxononanoate <=> S-Adenosyl-4-methylthio-2-oxobutanoate + 7,8-Diaminononanoate
Protein N(pi)-phospho-L-histidine + D-Fructose <=> Protein histidine + D-Fructose 1-phosphate
Sorbitol 6-phosphate + NADP+ <=> Sorbose 1-phosphate + NADPH + H+
D-Tagatose 6-phosphate + ATP <=> D-Tagatose 1,6-bisphosphate + ADP
CTP + D-Tagatose 6-phosphate <=> CDP + D-Tagatose 1,6-bisphosphate
UTP + D-Tagatose 6-phosphate <=> UDP + D-Tagatose 1,6-bisphosphate
ITP + D-Tagatose 6-phosphate <=> IDP + D-Tagatose 1,6-bisphosphate
D-Galactose 6-phosphate <=> D-Tagatose 6-phosphate
ATP + L-Fuculose <=> ADP + L-Fuculose 1-phosphate
L-Histidinol phosphate + 2-Oxoglutarate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + L-Glutamate
L-Ribulose 5-phosphate <=> L-Xylulose 5-phosphate
ATP + (R)-5-Phosphomevalonate <=> ADP + (R)-5-Diphosphomevalonate
1,2,3-Trihydroxybenzene + Oxygen <=> gamma-Oxalocrotonate
Gallate <=> 1,2,3-Trihydroxybenzene + CO2
5-Amino-2-oxopentanoic acid <=> 1-Pyrroline-2-carboxylate + H2O
5-Amino-2-oxopentanoic acid + Urea <=> 5-Guanidino-2-oxopentanoate + H2O
7,8-Dihydro-7,8-dihydroxykynurenate + NAD+ <=> 7,8-Dihydroxykynurenate + NADH + H+
7,8-Dihydroxykynurenate + Oxygen <=> 5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate
3-Deoxy-D-manno-octulosonate 8-phosphate + Orthophosphate <=> Phosphoenolpyruvate + D-Arabinose 5-phosphate + H2O
6-Phospho-beta-D-galactoside + H2O <=> Alcohol + D-Galactose 6-phosphate
Lactose 6'-phosphate + H2O <=> beta-D-Glucose + D-Galactose 6-phosphate
ATP + Nucleoside 5'-phosphate <=> AMP + 5'-Phosphonucleoside 3'-diphosphate
3',5'-Cyclic nucleotide + H2O <=> Nucleoside 5'-phosphate
O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate
(-)-trans-Isopiperitenol + NAD+ <=> (-)-Isopiperitenone + NADH + H+
(2E,6E)-Farnesol + NADP+ <=> 2-trans,6-trans-Farnesal + NADPH + H+
(2E,6E)-Farnesol <=> (2Z,6E)-Farnesol
4-Hydroxy-L-glutamate + 2-Oxoglutarate <=> 4-Hydroxy-2-oxoglutarate + L-Glutamate
UDP-glucose + Flavonol <=> UDP + Flavonol 3-O-beta-D-glucoside
UDP-D-xylose + Flavonol 3-O-D-glycoside <=> UDP + Flavonol 3-O-D-xylosylglycoside
(R)-4'-Phosphopantothenoyl-L-cysteine <=> Pantetheine 4'-phosphate + CO2
2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate
S-Adenosylmethioninamine + 1,3-Diaminopropane <=> 5'-Methylthioadenosine + Norspermidine + H+
ATP + [Acetyl-CoA carboxylase] <=> ADP + [Acetyl-CoA carboxylase] phosphate
[Acetyl-CoA carboxylase] phosphate + H2O <=> [Acetyl-CoA carboxylase] + Orthophosphate
ATP + beta-Adrenergic receptor <=> ADP + Phospho-beta-adrenergic receptor
(3S)-3,6-Diaminohexanoate <=> (3S,5S)-3,5-Diaminohexanoate
(S)-3-Hydroxybutanoyl-CoA <=> (R)-3-Hydroxybutanoyl-CoA
2-Hydroxy-3-oxopropanoate + Pyruvate <=> 2-Dehydro-3-deoxy-D-glucarate
2-Hydroxycyclohexan-1-one + NAD+ <=> Cyclohexane-1,2-dione + NADH + H+
trans-1,2-Cyclohexanediol + NAD+ <=> 2-Hydroxycyclohexan-1-one + NADH + H+
2-Hydroxycyclohexan-1-one + Oxygen + NADPH + H+ <=> 6-Hydroxyhexan-6-olide + NADP+ + H2O
4-Trimethylammoniobutanal + NAD+ + H2O <=> 4-Trimethylammoniobutanoate + NADH + H+
4-Trimethylammoniobutanal + Glycine <=> (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
ATP + N(pi)-Methyl-L-histidine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-N(pi)-methyl-L-histidine
beta-Alanyl-N(pi)-methyl-L-histidine + H2O <=> beta-Alanine + N(pi)-Methyl-L-histidine
3'-Phosphoadenylyl sulfate + Quercetin 3,3'-bissulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,3',7-trissulfate
Hydroxyproline + NAD+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADH + H+
Hydroxyproline + NADP+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADPH + H+
Hydroxyproline <=> cis-4-Hydroxy-D-proline
UDP-glucose + Gallate <=> UDP + 1-O-Galloyl-beta-D-glucose
2,3-Bisphospho-D-glycerate + ATP <=> Cyclic 2,3-bisphospho-D-glycerate + ADP + Orthophosphate
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
3,4-Dihydroxyphenylacetaldehyde + NAD+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADH + H+
3,4-Dihydroxyphenylacetaldehyde + NADP+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADPH + H+
3,4-Dihydroxyphenylacetate + Oxygen <=> 2-Hydroxy-5-carboxymethylmuconate semialdehyde
S-Adenosyl-L-methionine + 3,4-Dihydroxyphenylacetate <=> S-Adenosyl-L-homocysteine + Homovanillate
4-Chlorophenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + Hydrochloric acid + NAD+
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Carboxy-cis,cis-muconate
3-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Carboxy-cis,cis-muconate
L-Glutamate 5-semialdehyde + Orthophosphate + NADP+ <=> L-Glutamyl 5-phosphate + NADPH + H+
ATP + Pseudouridine <=> ADP + Pseudouridine 5'-phosphate
3-Carboxy-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + Thiamin diphosphate
UDP-N-acetyl-D-mannosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-D-mannosaminouronate + 2 NADH + 2 H+
GTP + alpha-D-Hexose 1-phosphate <=> Diphosphate + GDPhexose
alpha-D-Hexose 1-phosphate <=> alpha-D-Hexose 6-phosphate
beta-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate
Vermelone + NADP+ <=> 1,3,8-Naphthalenertriol + NADPH + H+
1-O-Sinapoyl-beta-D-glucose + (S)-Malate <=> D-Glucose + Sinapoyl malate
17alpha,20alpha-Dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+
17alpha-Hydroxypregnenolone + NAD+ <=> 17alpha-Hydroxyprogesterone + NADH + H+
D-myo-Inositol 1,3-bisphosphate + H2O <=> Inositol 1-phosphate + Orthophosphate
sn-Glycero-3-phospho-1-inositol + H2O <=> Glycerol + Inositol 1-phosphate
1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol
D-myo-Inositol 1,2-cyclic phosphate + H2O <=> Inositol 1-phosphate
2-Acyl-sn-glycero-3-phosphocholine <=> 1-Acyl-sn-glycero-3-phosphocholine
(R)-3-(4-Hydroxyphenyl)lactate + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + NADH + H+
(R)-3-(4-Hydroxyphenyl)lactate + NADP+ <=> 3-(4-Hydroxyphenyl)pyruvate + NADPH + H+
3-(4-Hydroxyphenyl)pyruvate <=> 4-Hydroxyphenylacetaldehyde + CO2
3-(4-Hydroxyphenyl)pyruvate <=> 2-Hydroxy-3-(4-hydroxyphenyl)propenoate
N,N-Dimethylaniline + Oxygen + NADPH + H+ <=> N,N-Dimethylaniline N-oxide + NADP+ + H2O
N,N-Dimethylaniline N-oxide <=> N-Methylaniline + Formaldehyde
Nicotinate D-ribonucleotide + H2O <=> Nicotinate D-ribonucleoside + Orthophosphate
Nicotinate D-ribonucleotide + ADP <=> Nicotinate D-ribonucleoside + ATP
Nicotinate D-ribonucleotide + Diphosphate + CO2 <=> Quinolinate + 5-Phospho-alpha-D-ribose 1-diphosphate
(3S,5S)-3,5-Diaminohexanoate + H2O + NAD+ <=> (S)-5-Amino-3-oxohexanoic acid + Ammonia + NADH + H+
3-Deoxy-D-manno-octulosonate 8-phosphate + H2O <=> 3-Deoxy-D-manno-octulosonate + Orthophosphate
CTP + 3-Deoxy-D-manno-octulosonate <=> Diphosphate + CMP-3-deoxy-D-manno-octulosonate
3-Hydroxy-2-methylpropanoyl-CoA + H2O <=> 3-Hydroxy-2-methylpropanoate + CoA
Lathosterol <=> 5alpha-Cholest-8-en-3beta-ol
Glucosylceramide + UDP-alpha-D-galactose <=> Lactosylceramide + UDP
Lactosylceramide + H2O <=> Glucosylceramide + D-Galactose
Dolichyl D-xylosyl phosphate + [Protein]-L-serine <=> Dolichyl phosphate + D-Xylosylprotein
1-Palmitoylglycerol 3-phosphate + NADP+ <=> Palmitoylglycerone phosphate + NADPH + H+
Octopamine <=> 4-Hydroxyphenylacetaldehyde + Ammonia
(-)-Sympatol <=> 4-Hydroxyphenylacetaldehyde + Methylamine
1-Phosphatidyl-D-myo-inositol + H2O <=> 1-Acylglycerophosphoinositol + Carboxylate
ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate
ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate
1-Phosphatidyl-1D-myo-inositol 3-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate
1-Phosphatidyl-D-myo-inositol <=> D-myo-Inositol 1,2-cyclic phosphate + 1,2-Diacyl-sn-glycerol
Caffeate + Oxygen <=> 3-(2-Carboxyethenyl)-cis,cis-muconate
S-Adenosyl-L-methionine + Caffeate <=> S-Adenosyl-L-homocysteine + Ferulate
Caffeate <=> 3,4-Dihydroxystyrene + CO2
3-(2-Hydroxyphenyl)propanoate + Oxygen + NADH + H+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + NAD+ + H2O
Phytic acid + H2O <=> D-myo-Inositol 1,2,4,5,6-pentakisphosphate + Orthophosphate
Phytic acid + H2O <=> Inositol 1,2,3,5,6-pentakisphosphate + Orthophosphate
(R)-3-(3,4-Dihydroxyphenyl)lactate + NAD+ <=> 3-(3,4-Dihydroxyphenyl)pyruvate + NADH + H+
Caffeoyl-CoA + (R)-3-(3,4-Dihydroxyphenyl)lactate <=> CoA + Rosmarinate
CTP + N-Methylethanolamine phosphate <=> Diphosphate + CDP-N-methylethanolamine
Protein lysine + 2-Oxoglutarate + Oxygen <=> Procollagen 5-hydroxy-L-lysine + Succinate + CO2
GTP + L-Hydroxylysine <=> GDP + 5-Phosphooxy-L-lysine
UDP-alpha-D-galactose + Procollagen 5-hydroxy-L-lysine <=> UDP + 5-(D-Galactosyloxy)-L-lysine-procollagen
(S)-Methylmalonate semialdehyde + CoA + NAD+ <=> (R)-Methylmalonyl-CoA + NADH + H+
Methylmalonate + CoA + ATP <=> (R)-Methylmalonyl-CoA + AMP + Diphosphate
ATP + 1-Amino-1-deoxy-scyllo-inositol <=> ADP + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate
3-Hydroxy-2-methylpyridine-5-carboxylate + Oxygen + NADH + H+ <=> 2-(Acetamidomethylene)succinate + NAD+
3-Hydroxy-2-methylpyridine-5-carboxylate + Oxygen + NADPH + H+ <=> 2-(Acetamidomethylene)succinate + NADP+
ATP + 2-Dehydro-3-deoxy-D-galactonate <=> ADP + 2-Dehydro-3-deoxy-6-phospho-D-galactonate
5,6,7,8-Tetrahydromethanopterin + NADP+ <=> 7,8-Dihydromethanopterin + H+ + NADPH
Formylmethanofuran + 5,6,7,8-Tetrahydromethanopterin <=> Methanofuran + 5-Formyl-5,6,7,8-tetrahydromethanopterin
CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+
CDP-4-dehydro-3,6-dideoxy-D-glucose + NADP+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+
1D-myo-Inositol 1,4-bisphosphate + H2O <=> myo-Inositol 4-phosphate + Orthophosphate
D-myo-Inositol 1,4,5-trisphosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + Orthophosphate
ATP + Dihydrostreptomycin 6-phosphate <=> ADP + Dihydrostreptomycin 3'alpha,6-bisphosphate
GDP-6-deoxy-D-talose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+
GDP-6-deoxy-D-mannose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+
GDP-6-deoxy-D-talose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
GDP-6-deoxy-D-mannose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
(9S,13S,15Z)-12-Oxo-10,11-dihydrophyto-15-enoate + NADP+ <=> (9S,13S,15Z)-12-Oxophyto-10,15-dienoate + NADPH + H+
(9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid <=> (9S,13S,15Z)-12-Oxophyto-10,15-dienoate
Dehydroepiandrosterone sulfate + H2O <=> Dehydroepiandrosterone + Sulfate
3'-Phosphoadenylyl sulfate + Dehydroepiandrosterone <=> Adenosine 3',5'-bisphosphate + Dehydroepiandrosterone sulfate
Androstenediol + NAD+ <=> Dehydroepiandrosterone + NADH + H+
Androstenediol + NADP+ <=> Dehydroepiandrosterone + NADPH + H+
Dehydroepiandrosterone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxydehydroepiandrosterone + NADP+ + H2O
Guanosine 3'-diphosphate 5'-triphosphate + H2O <=> Guanosine 3',5'-bis(diphosphate) + Orthophosphate
S-Adenosyl-L-methionine + Phospholipid olefinic fatty acid <=> S-Adenosyl-L-homocysteine + Phospholipid methylene fatty acid
S-Adenosyl-L-methionine + Phospholipid olefinic fatty acid <=> S-Adenosyl-L-homocysteine + Phospholipid cyclopropane fatty acid
1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> Aldehyde + sn-Glycero-3-phosphoethanolamine
1-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine
2-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine
alpha-D-Galactosyl-(1->3)-1D-myo-inositol + Raffinose <=> myo-Inositol + Stachyose
N4-(Acetyl-beta-D-glucosaminyl)asparagine + H2O <=> N-Acetyl-beta-D-glucosaminylamine + L-Aspartate
2',3'-Cyclic nucleotide + H2O <=> Nucleoside 2'-phosphate
2',3'-Cyclic nucleotide + H2O <=> Nucleoside 3'-phosphate
S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine
Glycine + Lipoylprotein <=> [Protein]-S8-aminomethyldihydrolipoyllysine + CO2
1D-myo-Inositol 1,3,4-trisphosphate + H2O <=> D-myo-Inositol 3,4-bisphosphate + Orthophosphate
ATP + 1D-myo-Inositol 1,3,4-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate
ATP + 1D-myo-Inositol 1,3,4-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,6-tetrakisphosphate
1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O <=> 1D-myo-Inositol 1,3,4-trisphosphate + Orthophosphate
3-(3,5-Diiodo-4-hydroxyphenyl)lactate + NAD+ <=> 3,5-Diiodo-4-hydroxyphenylpyruvate + NADH + H+
ATP + D-myo-Inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate
1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + Orthophosphate
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol
Acetyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine
Acyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 1-Radyl-2-acyl-sn-glycero-3-phosphocholine
4-Hydroxy-2-quinolinecarboxylic acid + Oxygen + NADH + H+ <=> 7,8-Dihydro-7,8-dihydroxykynurenate + NAD+
4-Hydroxy-2-quinolinecarboxylic acid + Oxygen + NADPH + H+ <=> 7,8-Dihydro-7,8-dihydroxykynurenate + NADP+
N-Acetyl-L-glutamate 5-semialdehyde + Orthophosphate + NADP+ <=> N-Acetyl-L-glutamate 5-phosphate + NADPH + H+
(R)-2-Hydroxybutane-1,2,4-tricarboxylate <=> (Z)-But-1-ene-1,2,4-tricarboxylate + H2O
4-(2-Aminophenyl)-2,4-dioxobutanoate <=> 4-Hydroxy-2-quinolinecarboxylic acid + H2O
ADP-D-ribosyl-[dinitrogen reductase] + H2O <=> [Dinitrogen reductase] + ADP-ribose
NAD+ + [Dinitrogen reductase] <=> Nicotinamide + ADP-D-ribosyl-[dinitrogen reductase]
1,8-Diazacyclotetradecane-2,9-dione + H2O <=> N-(6-Aminohexanoyl)-6-aminohexanoate
ATP + [Pyruvate dehydrogenase (acetyl-transferring)] <=> ADP + [Pyruvate dehydrogenase (acetyl-transferring)] phosphate
[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H2O <=> [Pyruvate dehydrogenase (acetyl-transferring)] + Orthophosphate
N6,N6,N6-Trimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinate + CO2
2-Acetyl-1-alkyl-sn-glycero-3-phosphate + H2O <=> 1-Alkyl-2-acetyl-sn-glycerol + Orthophosphate
Acetyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphate
S-Adenosyl-L-methionine + 3,7-Di-O-methylquercetin <=> S-Adenosyl-L-homocysteine + 3,7,4'-Tri-O-methylquercetin
D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + H2O
5-Amino-6-(5'-phospho-D-ribitylamino)uracil + NADP+ <=> 5-Amino-6-(5'-phosphoribosylamino)uracil + NADPH + H+
2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O <=> 5-Amino-6-(5'-phosphoribosylamino)uracil + Ammonia
Phosphoenolpyruvate + Shikimate 3-phosphate <=> Orthophosphate + 5-O-(1-Carboxyvinyl)-3-phosphoshikimate
3-Hydroxy-2-methylpyridine-4,5-dicarboxylate <=> 3-Hydroxy-2-methylpyridine-5-carboxylate + CO2
Biphenyl-2,3-diol + Oxygen <=> 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
2,6-Dioxo-6-phenylhexanoate + NADP+ <=> 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + NADPH + H+
5,10-Methenyltetrahydromethanopterin + H2O <=> 5-Formyl-5,6,7,8-tetrahydromethanopterin + H+
(3E)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate + H2O <=> 2-Carboxybenzaldehyde + Pyruvate
1-Hydroxy-2-naphthoate + Oxygen <=> (3E)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate
1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O <=> 3-beta-D-Galactosyl-sn-glycerol + 2 Carboxylate
CMP-N-acetylneuraminate + 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> CMP + 1,2-Diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol
ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate + CO2
ATP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine <=> ADP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine
Aminoimidazole ribotide + S-Adenosyl-L-methionine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO
ATP + [L-Glutamate:ammonia ligase (ADP-forming)] <=> Diphosphate + Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]
Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + Orthophosphate <=> ADP + [L-Glutamate:ammonia ligase (ADP-forming)]
1-Acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD+ <=> 1-Acyl-2-linoleoyl-sn-glycero-3-phosphocholine + NADH + H+
1-Acyl-2-oleoyl-sn-glycero-3-phosphocholine + Oxygen + NADH + H+ <=> 1-Acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + NAD+ + H2O
L-Arginine + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate <=> L-Ornithine + 1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate
ATP + 1D-myo-Inositol 1,3,4,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
ATP + 1D-myo-Inositol 3,4,5,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
N-Acetyl-D-glucosaminylphosphatidylinositol + H2O <=> 6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol + Acetate
UDP-alpha-D-galactose + Lactosylceramide <=> UDP + alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + GM3
CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide
UDP-N-acetyl-D-galactosamine + Lactosylceramide <=> UDP + GA2
Lactosylceramide + N-Acetylneuraminate <=> GM3 + H2O
GA2 + H2O <=> Lactosylceramide + N-Acetyl-D-galactosamine
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O
ATP + Geranoyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA
3alpha,7alpha,12beta-Trihydroxy-5beta-cholanate + NADP+ <=> 3alpha,7alpha-Dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O <=> 1-Guanidino-1-deoxy-scyllo-inositol + Orthophosphate
5-O-Methyl-myo-inositol + NAD+ <=> 2D-5-O-Methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+
D-Pinitol + NADP+ <=> 2D-5-O-Methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH + H+
1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol + Pyruvate <=> 1D-1-Guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-Alanine
ATP + 6-(Hydroxymethyl)-7,8-dihydropterin <=> AMP + 6-Hydroxymethyl-7,8-dihydropterin diphosphate
7,8-Dihydroneopterin <=> Glycolaldehyde + 6-(Hydroxymethyl)-7,8-dihydropterin
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + NAD+ + H2O <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + NADH + H+
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate <=> Indoleglycerol phosphate + CO2 + H2O
N-(5-Phospho-D-ribosyl)anthranilate <=> 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
Phylloquinone + Oxidized dithiothreitol + H2O <=> Vitamin K1 epoxide + Dithiothreitol
3-Hydroxy-vitamin K + Oxidized dithiothreitol <=> Vitamin K1 epoxide + Dithiothreitol
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-alpha-D-galactosaminyl-polypeptide <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl-R
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->6)-[N-acetyl-beta-D-glucosaminyl-(1->3)]-N-acetyl-alpha-D-galactosaminyl-R
[3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate + H2O <=> [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] + Orthophosphate
ATP + [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] <=> ADP + [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate
4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate + H2O <=> 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + Sulfate
4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + Sulfate
GDP-L-fucose + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> GDP + beta-D-Galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-D-glucosaminyl-R
Prostaglandin I2 + NADP+ <=> (5Z,13E)-6,9alpha-Epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate + NADPH + H+
Prostaglandin I2 + H2O <=> 6-Keto-prostaglandin F1alpha
RX + Glutathione <=> Halide + R-S-Glutathione
Bromochloromethane + H2O <=> Formaldehyde + Bromide + Cl- + 2 H+
L-Cysteine + Hydrogen cyanide <=> Hydrogen sulfide + 3-Cyano-L-alanine
UDP-glucose + ROH <=> UDP + beta-D-Glucoside
beta-D-Glucoside + H2O <=> D-Glucose + ROH
L-Cysteine-S-conjugate + H2O <=> Aryl thiol + Ammonia + Pyruvate
ATP + dIDP <=> ADP + dITP
dITP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Diphosphate
2-Hydroxyglutarate + FAD <=> 2-Oxoglutarate + FADH2
PQQH2 + Propynoate <=> 2-Propynal + PQQ + H2O
2',3'-Cyclic AMP + H2O <=> 3'-AMP
2',3'-Cyclic UMP + H2O <=> 3'-UMP
Hydroiodic acid + 3-Iodo-L-tyrosine <=> Iodine + L-Tyrosine
Maleic acid + Ammonia <=> Maleamate + H2O
alpha-Aminopropiononitrile + 2 H2O <=> Alanine + Ammonia
Benzene + Oxygen + NADH + H+ <=> cis-1,2-Dihydrobenzene-1,2-diol + NAD+
Butanal + NADH + H+ <=> 1-Butanol + NAD+
Butanal + NADPH + H+ <=> 1-Butanol + NADP+
Cyanate + H+ + HCO3- <=> CO2 + Carbamate
UDP-glucose + Methylazoxymethanol <=> UDP + Cycasin
UDP-glucose + 7,8-Dihydroxycoumarin <=> UDP + Daphnin
Gallate + Oxygen <=> 2-Pyrone-4,6-dicarboxylate + H2O
Gallate + Oxygen <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
Gallate + Methanol <=> 3-O-Methylgallate + H2O
Acetyl-CoA + Histone-L-lysine <=> CoA + Histone N6-acetyl-L-lysine
3'-Phosphoadenylyl sulfate + Keratan sulfate <=> Adenosine 3',5'-bisphosphate + Keratan sulfate
S-Adenosyl-L-methionine + Loganate <=> S-Adenosyl-L-homocysteine + Loganin
Secondary alcohol + NADP+ <=> Ketone + NADPH + H+
UDP-glucose + Salicyl alcohol <=> UDP + Salicin
Toluene + Oxygen + NADH + H+ <=> Toluene-cis-dihydrodiol + NAD+
Toluene + Oxygen + NADH + H+ <=> o-Cresol + NAD+ + H2O
Toluene + Oxygen + NADPH + H+ <=> 3-Cresol + NADP+ + H2O
Atropine + H2O <=> Tropine + Tropate
Tropate + Tropine <=> L-Hyoscyamine + H2O
UDP-glucose + Vitexin <=> Vitexin 2''-O-beta-D-glucoside + UDP
3-Cresol + Oxygen + NADPH + H+ <=> 2,3-Dihydroxytoluene + NADP+ + H2O
6-Methylsalicylate <=> 3-Cresol + CO2
4-Cresol + Oxygen + NADPH + H+ <=> 4-Methylcatechol + NADP+ + H2O
S-Adenosyl-L-methionine + Apigenin <=> S-Adenosyl-L-homocysteine + Acacetin
Allyl alcohol + NADP+ <=> Acrolein + NADPH + H+
UDP-glucose + Alizarin <=> UDP + 1-Hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone
UDP-glucose + Apigenin <=> UDP + Apigenin 7-O-beta-D-glucoside
ATP + D-Allose <=> ADP + D-Allose 6-phosphate
D-Apiitol + NAD+ <=> D-Apiose + NADH + H+
N-Feruloylglycine + H2O <=> Ferulate + Glycine
Geraniol + NADP+ <=> Geranial + NADPH + H+
Indan-1-ol + NAD+ <=> Indanone + NADH + H+
Indan-1-ol + NADP+ <=> Indanone + NADPH + H+
L-Glycol + NAD+ <=> 2-Hydroxycarbonyl compound + NADH + H+
L-Glycol + NADP+ <=> 2-Hydroxycarbonyl compound + NADPH + H+
L-Xylose + NADP+ <=> L-Xylono-1,4-lactone + NADPH + H+
S-Adenosyl-L-methionine + Luteolin <=> S-Adenosyl-L-homocysteine + Chrysoeriol
UDP-glucose + Luteolin <=> UDP + Luteolin 7-O-beta-D-glucoside
UDP-glucuronate + Luteolin <=> UDP + Luteolin 7-O-glucuronide
Eriodictyol + 2-Oxoglutarate + Oxygen <=> Luteolin + Succinate + CO2 + H2O
Morphine + NAD+ <=> Morphinone + NADH + H+
Morphine + NADP+ <=> Morphinone + NADPH + H+
Ricinine + 2 H2O <=> 3-Carboxy-4-methoxy-N-methyl-2-pyridone + Ammonia
UDP-glucose + Scopoletin <=> UDP + Scopolin
ATP + Hydrogen selenide + H2O <=> AMP + Selenophosphoric acid + Orthophosphate
O-Acetyl-L-serine + Hydrogen selenide <=> L-Selenocysteine + Acetate
Syringin + H2O <=> Sinapyl alcohol + D-Glucose
UDP-glucose + Sinapyl alcohol <=> UDP + Syringin
ATP + Viomycin <=> ADP + O-Phosphoviomycin
o-Cresol + Oxygen + NADH + H+ <=> 2,3-Dihydroxytoluene + NAD+ + H2O
Agaritine + Acceptor <=> 4-Hydroxymethylphenylhydrazine + gamma-L-Glutamyl-acceptor
Cetraxate benzyl ester + H2O <=> Cetraxate + Benzyl alcohol
ATP + Peptide diphthine + Ammonia + H+ <=> AMP + Diphosphate + Peptide diphthamide
Ephedrine + NAD+ <=> (R)-2-Methylimino-1-phenylpropan-1-ol + NADH + H+
3-beta-D-Galactosyl-sn-glycerol + H2O <=> Galactose + Glycerol
Galactosylceramide + H2O <=> D-Galactose + N-Acylsphingosine
alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O <=> D-Galactose + Lactosylceramide
N-Methylhexanamide + H2O <=> Hexanoic acid + Methylamine
Acetyl-CoA + Imidazole <=> CoA + N-Acetylimidazole
Kievitone hydrate <=> Kievitone + H2O
S-Adenosyl-L-methionine + Licodione <=> S-Adenosyl-L-homocysteine + 2'-O-Methyllicodione
Limonoate D-ring-lactone + H2O <=> Limonoate
UDP-glucose + Acetone cyanohydrin <=> UDP + Linamarin
Linoleate + Oxygen <=> (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoic acid
Linoleate <=> Rumenic acid
Melatonin + Oxygen <=> Formyl-N-acetyl-5-methoxykynurenamine
Phthalate + Oxygen + NADH + H+ <=> cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+
ATP + Phytanate + CoA <=> AMP + Diphosphate + Phytanoyl-CoA
S-Adenosyl-L-methionine + O-Demethylpuromycin <=> S-Adenosyl-L-homocysteine + Puromycin
Stachyose + H2O <=> Raffinose + D-Galactose
Stachyose + H2O <=> D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + D-Fructose
Leucocyanidin + NADP+ <=> Taxifolin + NADPH + H+
Taxifolin + Oxygen + NADH + H+ <=> 2,3-Dihydrogossypetin + NAD+ + H2O
Taxifolin + Oxygen + NADPH + H+ <=> 2,3-Dihydrogossypetin + NADP+ + H2O
Eriodictyol + 2-Oxoglutarate + Oxygen <=> Taxifolin + Succinate + CO2
Testololactone + H2O <=> Testolate
Vicianose + Mandelonitrile <=> Vicianin + H2O
Vitamin K + NADH + H+ <=> Reduced Vitamin K + NAD+
Vitamin K + Oxidized dithiothreitol + H2O <=> Vitamin K epoxide + Dithiothreitol
Cadaverine <=> Piperideine
Coformycin + NADP+ <=> 8-Oxocoformycin + NADPH + H+
Acetyl-CoA + Cysteamine <=> CoA + S-Acetylthioethanolamine
D-Fuconate <=> 2-Dehydro-3-deoxy-D-fuconate + H2O
L-Dopachrome + 3,4-Dihydroxy-L-phenylalanine <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + Dopaquinone
L-Dopachrome <=> 5,6-Dihydroxyindole-2-carboxylate
L-Dopachrome <=> 5,6-Dihydroxyindole + CO2
5alpha-Ergosta-7,22-diene-3beta,5-diol <=> Ergosterol + H2O
UDP-alpha-D-galactose + Galactogen <=> UDP + (1->6)-beta-D-Galactosylgalactogen
UDP-glucose + Gibberellin A3 <=> UDP + Gibberellin 2-O-beta-D-glucoside
UDP-glucose + Glycogenin <=> UDP + alpha-D-Glucosylglycogenin
Bis-D-fructose 2',1:2,1'-dianhydride + H2O <=> Inulobiose
UDP-glucose + Isovitexin <=> Isovitexin 2''-O-beta-D-glucoside + UDP
L-Fuconate <=> 2-Dehydro-3-deoxy-L-fuconate + H2O
Lanosterol + NADPH + H+ <=> 24,25-Dihydrolanosterol + NADP+
ATP + D-Lombricine <=> ADP + N-Phospho-D-lombricine
Dihydrocoumarin + H2O <=> 3-(2-Hydroxyphenyl)propanoate
(S)-2-Methylmalate <=> Mesaconate + H2O
Mesaconate + H2O <=> L-threo-3-Methylmalate
Mesaconate + CoA <=> 2-Methylfumaryl-CoA + H2O
L-threo-3-Methylaspartate <=> Mesaconate + Ammonia
Oripavine + 2-Oxoglutarate + Oxygen <=> Morphinone + Formaldehyde + Succinate + CO2
Diphosphate + N-D-Ribosylpurine <=> Orthophosphate + Purine mononucleotide
3'-Phosphoadenylyl sulfate + Psychosine <=> Adenosine 3',5'-bisphosphate + Psychosine sulfate
S-Adenosyl-L-methionine + Thiopurine <=> S-Adenosyl-L-homocysteine + 6-Methylmercaptopurine
Triacetate lactone + H2O <=> Triacetate
Raucaffricine + H2O <=> Vomilenine + D-Glucose
(Alginate)n <=> Oligouronide with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl group
(S,S)-Butane-2,3-diol + NAD+ <=> (S)-Acetoin + NADH + H+
gamma-Butyrolactone + H2O <=> 4-Hydroxyacid
3-(2-Hydroxyphenyl)propanoate + NAD+ <=> trans-2-Hydroxycinnamate + NADH + H+
UDP-glucose + trans-2-Hydroxycinnamate <=> UDP + trans-beta-D-Glucosyl-2-hydroxycinnamate
Albendazole + Oxygen + NADPH + H+ <=> Albendazole S-oxide + NADP+ + H2O
11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADP+ <=> Aldosterone + NADPH + H+
Chlordecone alcohol + NADP+ <=> Chlordecone + NADPH + H+
Choloyl-CoA + Glycine <=> CoA + Glycocholate
Propanoyl-CoA + Choloyl-CoA <=> CoA + 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA
Choloyl-CoA + Taurine <=> CoA + Taurocholate
S-Adenosyl-L-methionine + Columbamine <=> S-Adenosyl-L-homocysteine + Palmatine
Isocorypalmine + 2 Oxygen <=> Columbamine + 2 Hydrogen peroxide
(24R,24(1)R)-Fucosterol epoxide <=> Desmosterol + Acetaldehyde
Desmosterol + S-Adenosyl-L-methionine <=> 24-Methylenecholesterol + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + N6-(Delta2-Isopentenyl)-adenine <=> 5'-Methylthioadenosine + Discadenine
Feruloyl-CoA + D-Galactarate <=> CoA + O-Feruloylgalactarate
Octadecanal + Oxygen + 2 NADPH + 2 H+ <=> Heptadecane + Formate + H2O + 2 NADP+
S-Adenosyl-L-methionine + Isoorientin <=> S-Adenosyl-L-homocysteine + Isoscoparine
(2S)-2-{[1-(R)-Carboxyethyl]amino}pentanoate + NAD+ + H2O <=> L-Norvaline + Pyruvate + NADH + H+
Threonate + NAD+ <=> 3-Dehydro-L-threonate + NADH + H+
(2S,3S)-2-Hydroxytridecane-1,2,3-tricarboxylate + CoA <=> Lauroyl-CoA + H2O + Oxaloacetate
Rifamycin B + Oxygen <=> Rifamycin O + Hydrogen peroxide
(6S)-Hydroxyhyoscyamine + 2-Oxoglutarate + Oxygen <=> Scopolamine + Succinate + CO2 + H2O
3-alpha(S)-Strictosidine + H2O <=> Tryptamine + Secologanin
Stipitatonate + H2O <=> Stipitatate + CO2
Trichodiene <=> Nivalenol
Protoaphin aglucone <=> Xanthoaphin + H2O
(+)-cis-Sabinol + NAD+ <=> (+)-Sabinone + NADH + H+
S-Adenosyl-L-methionine + 2-Iodophenol <=> S-Adenosyl-L-homocysteine + 2-Iodophenol methyl ether
3-Oxododecanoic acid <=> 2-Undecanone + CO2
(5-L-Glutamyl)-L-amino acid <=> 5-Oxoproline + L-Amino acid
epsilon-Caprolactone + H2O <=> 6-Hydroxyhexanoic acid
7beta-Hydroxysteroid + NADP+ <=> 7-Oxosteroid + NADPH + H+
Acyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol
2,3-Dehydroacyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol
Aminoacetone + CO2 <=> L-2-Amino-3-oxobutanoic acid
(R)-1-Aminopropan-2-ol + NAD+ <=> Aminoacetone + NADH + H+
Acetyl-CoA + 2-Arylethylamine <=> CoA + N-Acetyl-2-arylethylamine
Asparagusate + NADH + H+ <=> 3-Sulfanyl-2-(sulfanylmethyl)propanoate + NAD+
Biotinyl-5'-AMP + CoA <=> AMP + Biotinyl-CoA
23,24-Dihydrocucurbitacin B + NAD+ <=> Cucurbitacin B + NADH + H+
23,24-Dihydrocucurbitacin B + NADP+ <=> Cucurbitacin B + NADPH + H+
Cycloartenol <=> Zymosterol
ATP + D-Hamamelose <=> ADP + D-Hamamelose 2(1)-phosphate
Acetyl-CoA + Gentamicin C <=> CoA + N3-Acetylgentamicin C
ATP + Hygromycin B <=> ADP + 7''-O-Phosphohygromycin
L-Rhamnono-1,4-lactone + H2O <=> L-Rhamnonate
L-Rhamnonate <=> 2-Dehydro-3-deoxy-L-rhamnonate + H2O
Cycloeucalenol <=> Obtusifoliol
Octanoyl-CoA + NADP+ <=> trans-Oct-2-enoyl-CoA + NADPH + H+
Octanoyl-CoA + FAD <=> trans-Oct-2-enoyl-CoA + FADH2
Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA
Octanoyl-CoA + L-Carnitine <=> CoA + L-Octanoylcarnitine
ATP + Oleandomycin <=> ADP + Oleandomycin 2'-O-phosphate
Nonane-4,6-dione + H2O <=> Pentan-2-one + Butanoic acid
Isopiperitenone <=> Piperitenone
ATP + Taurocyamine <=> ADP + N-Phosphotaurocyamine
5,12-Dihydroxanthommatin + NAD+ <=> Xanthommatin + NADH + H+
S-Adenosyl-L-methionine + m7G(5')pppAm-mRNA <=> S-Adenosyl-L-homocysteine + m7G(5')pppm6Am-mRNA
tRNA guanine + Queuine <=> tRNA queuine + Guanine
(R)-Mandelate + NAD+ <=> alpha-Oxo-benzeneacetic acid + NADH + H+
(S)-Mandelate <=> (R)-Mandelate
(S)-Mandelate + NAD+ <=> alpha-Oxo-benzeneacetic acid + NADH + H+
(S)-Mandelate + Tetrahydropteridine + Oxygen <=> (S)-4-Hydroxymandelate + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
Pyruvate oxime + Acetone <=> Pyruvate + Acetone oxime
UDP-glucose + Anthocyanidin <=> UDP + Anthocyanidin 3-O-beta-D-glucoside
Aristolochene <=> PR-toxin
2 Dimethylallyl diphosphate + Aspulvinone E <=> 2 Diphosphate + Aspulvinone H
Blasticidin S + H2O <=> Deaminohydroxyblasticidin S + Ammonia
Cellotetraose + H2O <=> Cellotriose + D-Glucose
Cellopentaose + H2O <=> Cellotetraose + D-Glucose
Deoxylimonate + H2O <=> Deoxylimononic acid D-ring-lactone
Monoamide of dicarboxylate + H2O <=> Dicarboxylate + Ammonia
S-Adenosyl-L-methionine + G(5')pppPur-mRNA + H+ <=> S-Adenosyl-L-homocysteine + m7G(5')pppR-mRNA
Gibberellin A44 diacid + 2-Oxoglutarate + Oxygen <=> Gibberellin A19 + Succinate + CO2 + H2O
Gibberellin A19 + 2 2-Oxoglutarate + 2 Oxygen <=> Gibberellin A20 + 3 CO2 + 2 Succinate + H2O
Gibberellin A20 + 2-Oxoglutarate + Oxygen <=> Gibberellin A29 + Succinate + CO2
2,5-Dioxopiperazine + H2O <=> Glycylglycine
L-Hyoscyamine + 2-Oxoglutarate + Oxygen <=> (6S)-Hydroxyhyoscyamine + Succinate + CO2
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
Phylloquinone + NADH + H+ <=> Phylloquinol + NAD+
ATP + Sedoheptulose <=> ADP + Sedoheptulose 1-phosphate
3-alpha(S)-Strictosidine + H2O <=> Strictosidine aglycone + D-Glucose
Trypanothione + NADP+ <=> Trypanothione disulfide + NADPH + H+
ATP + Glutathionylspermidine + Glutathione <=> ADP + Orthophosphate + Trypanothione
beta-Carotene <=> Lycopene
gamma-Carotene <=> beta-Carotene
dTDP-galactose + H2O + 2 NAD+ <=> dTDP-D-galacturonate + 2 NADH + 2 H+
(2S)-Flavan-4-ol + NADP+ <=> (2S)-Flavanone + NADPH + H+
GTP + (5')ppPur-mRNA <=> Diphosphate + G(5')pppPur-mRNA
GDP-mannose + Glucomannan <=> GDP + Glucomannan longer by one mannose unit
(S)-2-Haloacid + H2O <=> (R)-2-Hydroxyacid + Halide
(S)-Reticuline + Oxygen <=> (S)-Scoulerine + Hydrogen peroxide
S-Adenosyl-L-methionine + 3'-Hydroxy-N-methyl-(S)-coclaurine <=> S-Adenosyl-L-homocysteine + (S)-Reticuline + H+
S-Adenosyl-L-methionine + (S)-Scoulerine <=> S-Adenosyl-L-homocysteine + Isocorypalmine
11-cis-Retinal <=> Iodopsin
2,3-Dehydroacyl-CoA + 2-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol
ATP + 5'-Dephospho-DNA <=> ADP + 5'-Phospho-DNA
Chlorophyllide + NADP+ <=> Protochlorophyllide + NADPH + H+
Corticosterone + NAD+ <=> 11-Dehydrocorticosterone + NADH + H+
Corticosterone + NADP+ <=> 11-Dehydrocorticosterone + NADPH + H+
11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADP+ <=> Corticosterone + NADPH + H+
2,2-Dialkylglycine + Pyruvate <=> Dialkyl ketone + CO2 + L-Alanine
Lauroyl-CoA + NADP+ <=> 2-trans-Dodecenoyl-CoA + NADPH + H+
Lauroyl-CoA + FAD <=> 2-trans-Dodecenoyl-CoA + FADH2
Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA
(3S,4S)-3-Hydroxytetradecane-1,3,4-tricarboxylate + CoA <=> Lauroyl-CoA + H2O + 2-Oxoglutarate
Geissoschizine + NADP+ <=> 4,21-Dehydrogeissoschizine + NADPH
Leukotriene B4 + NAD+ <=> 12-Keto-leukotriene B4 + H+ + NADH
Leukotriene B4 + NADP+ <=> 12-Keto-leukotriene B4 + H+ + NADPH
Leukotriene C4 + Amino acid <=> Leukotriene D4 + 5-L-Glutamyl amino acid
Maleylpyruvate <=> 3-Fumarylpyruvate
(S)-Methylmalonate semialdehyde + NAD+ + H2O <=> Methylmalonate + NADH + H+
5-Methylbarbiturate + 2 H2O <=> Methylmalonate + Urea
Methylmalonate + Hydrogen peroxide <=> (S)-Methylmalonate semialdehyde + Oxygen + H2O
Methylmalonate <=> (S)-Methylmalonate semialdehyde
N-Acetylisatin <=> N-Acetylindoxyl + Oxygen
[Peptide]-(2S)-2-hydroxyglycine <=> [Peptide]-amide + Glyoxylate
Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine
ATP + Protoporphyrin + Magnesium cation + H2O <=> ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+
Thromboxane A2 + H2O <=> Thromboxane B2
UDP-L-rhamnose + NADP+ <=> UDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+
UDP-L-rhamnose + Flavonol 3-O-beta-D-glucoside <=> UDP + Flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside]
UDP-glucosamine <=> UDP-galactosamine
1,2-Dihydrosantonin + NAD+ <=> alpha-Santonin + NADH + H+
1,2-Dihydrosantonin + NADP+ <=> alpha-Santonin + NADPH + H+
Acetyl-CoA + (E)-Glutaconate <=> Acetate + Glutaconyl-1-CoA
1-Methyladenosine + H2O <=> 1-Methyladenine + D-Ribose
10-Hydroxydecanoic acid + NAD+ <=> 10-Oxodecanoate + NADH + H+
2-Aminomuconate + H2O <=> gamma-Oxalocrotonate + Ammonia
2-Aminomuconate semialdehyde + NAD+ + H2O <=> 2-Aminomuconate + H+ + NADH
Benzene-1,2,4-triol + Oxygen <=> 2-Maleylacetate
2-Maleylacetate <=> 3-Hydroxy-cis,cis-muconate
cis-4-Carboxymethylenebut-2-en-4-olide + H2O <=> 2-Maleylacetate
(S)-3-Methyl-2-oxopentanoic acid <=> 2-Methylbutanal + CO2
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
2-Methylmaleate + H2O <=> D-threo-3-Methylmalate
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
N1-Acetylspermine + Oxygen + H2O <=> Spermidine + 3-Acetamidopropanal + Hydrogen peroxide
beta-Nitropropanoate + NADP+ <=> 3-Nitroacrylate + NADPH + H+
S-Alkyl-L-cysteine S-oxide <=> Alkyl sulfenate + Dehydroalanine
Acetyl-CoA + D-Phenylalanine <=> CoA + N-Acetyl-D-phenylalanine
dATP + Depurinated DNA <=> Deoxyribose triphosphate + DNA adenine
Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O
Glycyrrhizinate + H2O <=> 1,2-beta-D-Glucuronosyl-D-glucuronate + Glycyrrhetinate
2-Methyleneglutarate <=> Methylitaconate
Monocarboxylic acid amide + H2O <=> Carboxylate + Ammonia
Acetyl-CoA + Alkane-alpha,omega-diamine <=> CoA + N-Acetyldiamine
N-Acetylindoxyl <=> Indoxyl
[Peptide]-glycine + 2 Ascorbate + Oxygen <=> [Peptide]-(2S)-2-hydroxyglycine + 2 Monodehydroascorbate + H2O
Protein dithiol + NAD+ <=> Protein disulfide + NADH + H+
Protein dithiol + NADP+ <=> Protein disulfide + NADPH + H+
Protein dithiol + Glutathione disulfide <=> Protein disulfide + 2 Glutathione
R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate
n Isopentenyl diphosphate <=> cis-1,4-Polyisoprene + n Diphosphate
Sinapyl alcohol + NADP+ <=> Sinapoyl aldehyde + NADPH + H+
ATP + beta-D-Fructose <=> ADP + beta-D-Fructose 6-phosphate
Sucrose 6-phosphate + H2O <=> D-Fructose + D-Glucose 6-phosphate
S-Adenosyl-L-methionine + m7G(5')pppR-mRNA <=> S-Adenosyl-L-homocysteine + m7G(5')pppRm-mRNA
GDP-mannose + Phosphomannan <=> GMP + Phosphomannan mannosephosphate
(S)-Allantoin <=> (R)(-)-Allantoin
UDP-D-xylose + 1,4-beta-D-Xylan <=> UDP + 1,4-beta-D-Xylan
2',3'-Cyclic CMP + H2O <=> 3'-CMP
3-Methyloxindole + NADP+ <=> 3-Methyleneoxindole + NADPH + H+
ATP + 4-Chlorobenzoate + CoA <=> AMP + Diphosphate + 4-Chlorobenzoyl-CoA
S-Adenosyl-L-methionine + 6-Hydroxymellein <=> S-Adenosyl-L-homocysteine + 6-Methoxymellein
beta-Alanyl-L-arginine + H2O <=> beta-Alanine + Amino acid(Arg-)
L-Formylkynurenine + H2O <=> Formylanthranilate + L-Alanine
Glutaconyl-1-CoA + H2O <=> 2-Hydroxyglutaryl-CoA
S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine
ATP + Hypotaurocyamine <=> ADP + N-Phosphohypotaurocyamine
L-Methionyl-tRNA + 10-Formyltetrahydrofolate <=> Tetrahydrofolate + N-Formylmethionyl-tRNA
L-Rhamnofuranose + NAD+ <=> L-Rhamnono-1,4-lactone + NADH + H+
N-Methyltyramine + S-Adenosyl-L-methionine <=> Hordenine + S-Adenosyl-L-homocysteine
ATP + O-Alkylglycerone <=> ADP + O-Alkylglycerone phosphate
(-)-Perillyl alcohol + NAD+ <=> Perillyl aldehyde + NADH + H+
3'-Phosphoadenylyl sulfate + Phenolic steroid <=> Adenosine 3',5'-bisphosphate + Steroid O-sulfate
Precorrin 2 + NAD+ <=> Sirohydrochlorin + NADH + H+
S-Adenosyl-L-methionine + Precorrin 2 <=> S-Adenosyl-L-homocysteine + Precorrin 3A + H+
2 S-Adenosyl-L-methionine + Uroporphyrin III <=> 2 S-Adenosyl-L-homocysteine + Sirohydrochlorin
Triiodothyronine + 2-Oxoglutarate <=> 3,5,3'-Triiodothyropyruvate + L-Glutamate
3-Iodo-L-tyrosine + 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Triiodothyronine + Dehydroalanine + 2 H2O
Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Xanthurenic acid + S-Adenosyl-L-methionine <=> 8-Methoxykynurenate + S-Adenosyl-L-homocysteine
Glutathione + [Glu(-Cys)]n-Gly <=> Glycine + [Glu(-Cys)]n+1-Gly
2,5-Dihydro-5-oxofuran-2-acetate <=> cis,cis-Muconate
2'-Hydroxydihydrodaidzein + NADP+ <=> 2'-Hydroxydaidzein + NADPH + H+
2-Butyne-1,4-diol + NAD+ <=> 4-Hydroxy-2-butynal + NADH + H+
2-Hydroxybiphenyl + Oxygen + NADH + H+ <=> Biphenyl-2,3-diol + NAD+ + H2O
Sinapoyl-CoA + Hydroxymalonate <=> CoA + Sinapoyltartronate
2-Hydroxymuconate <=> gamma-Oxalocrotonate
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-(ADP)-2-phosphoglycerate + H2O <=> 3-(ADP)-glycerate + Orthophosphate
3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O
3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O
Hydroiodic acid + 3,5-Diiodo-L-tyrosine <=> 3-Iodo-L-tyrosine + Iodine
Chenodeoxycholate + CoA <=> Chenodeoxycholoyl-CoA + H2O
Glycochenodeoxycholate + H2O <=> Chenodeoxycholate + Glycine
Taurochenodeoxycholate + H2O <=> Chenodeoxycholate + Taurine
Chenodeoxycholate + FADH2 <=> Lithocholic acid + FAD + H2O
Aryl dialkyl phosphate + H2O <=> Dialkyl phosphate + Phenol
Estrone 3-sulfate + H2O <=> Sulfate + Estrone
Pentachlorophenol + Oxygen + NADPH + H+ <=> Chloranil + Cl- + NADP+ + H2O
Protein glutamine + Alkylamine <=> Protein N5-alkylglutamine + Ammonia
Pyrimidodiazepine + Glutathione disulfide + H2O <=> 6-Pyruvoyltetrahydropterin + 2 Glutathione
3'-Phosphoadenylyl sulfate + Taurolithocholate <=> Adenosine 3',5'-bisphosphate + Taurolithocholate sulfate
Tetradecanoyl-CoA + NADP+ <=> trans-Tetradec-2-enoyl-CoA + NADPH + H+
Tetradecanoyl-CoA + FAD <=> trans-Tetradec-2-enoyl-CoA + FADH2
Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA
Tetradecanoyl-CoA + N-Terminal-glycyl-[protein] <=> CoA + N-Terminal-N-tetradecanoylglycyl-[protein]
[Pyruvate kinase] phosphate + H2O <=> [Pyruvate kinase] + Orthophosphate
(E,E)-Piperoyl-CoA + Piperidine <=> CoA + Piperine
(R)-2-Methylmalate + CO2 <=> Parapyruvate + H2O
UDP-glucose + 1,3-alpha-D-Glucan <=> UDP + 1,3-alpha-D-Glucan
2,4-Dichlorophenol + Oxygen + NADPH + H+ <=> 3,5-Dichlorocatechol + NADP+ + H2O
Acetyl-CoA + 2-Hydroxyglutarate <=> Acetate + 2-Hydroxyglutaryl-CoA
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
ATP + 2-Methylpropanoate <=> ADP + 2-Methylpropanoyl phosphate
3-Chloro-L-alanine + Thioglycolate <=> S-Carboxymethyl-L-cysteine + Cl-
UDP-glucose + 4-Coumaryl alcohol <=> UDP + 4-Hydroxycinnamyl alcohol 4-D-glucoside
4-Hydroxycinnamyl alcohol 4-D-glucoside + H2O <=> 4-Coumaryl alcohol + D-Glucose
Aldoxime + CO2 <=> 2-Oxoacid oxime
Benzyl thiocyanate <=> Benzyl isothiocyanate
L-Glutamine + D-Glutamyl-peptide <=> Ammonia + 5-L-Glutamyl-D-glutamyl-peptide
D-Glutamine + D-Glutamyl-peptide <=> Ammonia + 5-D-Glutamyl-D-glutamyl-peptide
S-Adenosyl-L-methionine + 16-Methoxy-2,3-dihydro-3-hydroxytabersonine <=> S-Adenosyl-L-homocysteine + Desacetoxyvindoline
Dodecanoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Dodecanoic acid
Galactosylceramide + UDP-alpha-D-galactose <=> Digalactosylceramide + UDP
3'-Phosphoadenylyl sulfate + Galactosylceramide <=> Adenosine 3',5'-bisphosphate + Sulfatide
Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O
Digalactosylceramide + H2O <=> Galactosylceramide + D-Galactose
(Indol-3-yl)acetamide <=> 3-Indoleacetonitrile + H2O
Palmitoyl-CoA + Mucus glycoprotein <=> CoA + O-Palmitoylglycoprotein
Palmitoyl-CoA + Myelin proteolipid <=> CoA + Myelin proteolipid O-palmitoylprotein
ATP + Myosin heavy chain <=> ADP + Myosin heavy-chain phosphate
Acetyl-CoA + Hydroxylaminobenzene <=> CoA + N-(Acetyloxy)benzenamine
N-Acetylputrescine + H2O + Oxygen <=> N4-Acetylaminobutanal + Ammonia + Hydrogen peroxide
N-Formiminoglycine <=> Imidazolone + H2O
N-Methylputrescine + Oxygen + H+ <=> 1-Methylpyrrolinium + Hydrogen peroxide + Ammonia
6-Acetamido-3-aminohexanoate + 2-Oxoglutarate <=> 6-Acetamido-3-oxohexanoate + L-Glutamate
N6-Acetyl-L-lysine + 2-Oxoglutarate <=> 6-Acetamido-2-oxohexanoate + L-Glutamate
ATP + 2-Succinylbenzoate + CoA <=> AMP + Diphosphate + 2-Succinylbenzoyl-CoA
2-Succinylbenzoate + H2O <=> (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
Peptide tryptophan + Oxygen <=> Peptide formylkynurenine
S-Adenosyl-L-methionine + Phenylethanolamine <=> S-Adenosyl-L-homocysteine + N-Methylphenylethanolamine
Phosphatidylserine + H2O <=> 2-Acyl-sn-glycero-3-phosphoserine + Fatty acid
1-(5-Phospho-D-ribosyl)-ATP + H2O <=> Phosphoribosyl-AMP + Diphosphate
Phosphoribosyl-AMP + H2O <=> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
Dimethylallyl diphosphate + AMP <=> Diphosphate + N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate
alpha-Pinene-oxide <=> (Z)-2-Methyl-5-isopropylhexa-2,5-dienal
1-Alkyl-2-acetyl-sn-glycerol + H2O <=> 1-Alkyl-sn-glycerol + Acetate
2-Acetamidofluorene + NAD+ + H2O <=> N-Hydroxy-2-acetamidofluorene + NADH + H+
2-Acetamidofluorene + NADP+ + H2O <=> N-Hydroxy-2-acetamidofluorene + NADPH + H+
2-Dehydro-D-glucose + Oxygen <=> 2-Dehydro-D-glucono-1,5-lactone + Hydrogen peroxide
2-Deoxy-D-gluconate + NAD+ <=> 3-Dehydro-2-deoxy-D-gluconate + NADH + H+
Malonyl-CoA + 3,4-Dichloroaniline <=> CoA + N-(3,4-Dichlorophenyl)-malonamate
3-Phosphonopyruvate + L-Glutamate <=> 2-Amino-3-phosphonopropanoate + 2-Oxoglutarate
3-Phosphonopyruvate <=> Phosphonoacetaldehyde + CO2
Triacylglycerol + 3beta-Hydroxysteroid <=> Diacylglycerol + 3beta-Hydroxysteroid ester
4-Acetamidobutanoyl-CoA + H2O <=> Acetate + 4-Aminobutanoyl-CoA
Acetyl-CoA + 5-Hydroxypentanoate <=> Acetate + 5-Hydroxypentanoyl-CoA
L-Glutaminyl-peptide <=> 5-Oxoprolyl-peptide + Ammonia
(+/-)-trans-Acenaphthene-1,2-diol + 2 NADP+ <=> Acenaphthenequinone + 2 NADPH + 2 H+
Anhydrotetracycline + Oxygen + NADPH + H+ <=> 5a,11a-Dehydrotetracycline + NADP+ + H2O
Benzene-1,2,4-triol + Oxygen <=> 3-Hydroxy-cis,cis-muconate
S-Adenosyl-L-methionine + Calmodulin L-lysine <=> S-Adenosyl-L-homocysteine + Calmodulin N6-methyl-L-lysine
Imidazole-4-acetaldehyde + NAD+ + H2O <=> Imidazole-4-acetate + NADH + H+
Imidazole-4-acetate + Oxygen + NADH + H+ <=> 4-Imidazolone-5-acetate + NAD+ + H2O
ATP + Imidazole-4-acetate + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O <=> ADP + Orthophosphate + 1-(5-Phosphoribosyl)imidazole-4-acetate + Diphosphate
N5-Acyl-L-ornithine ester + H2O <=> N5-Acyl-L-ornithine + Alcohol
UDP-glucose + N6-Alkylaminopurine <=> UDP + N6-Alkylaminopurine-7-beta-D-glucoside
Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein]
Peptide L-aspartate + 2-Oxoglutarate + Oxygen <=> Peptide 3-hydroxy-L-aspartate + Succinate + CO2
NAD+ + Peptide diphthamide <=> Nicotinamide + Peptide N-(ADP-D-ribosyl)diphthamide
Protein N(pi)-phospho-L-histidine + L-Sorbose <=> Protein histidine + Sorbose 1-phosphate
S-Adenosyl-L-methionine + Isocorypalmine <=> S-Adenosyl-L-homocysteine + Tetrahydropalmatine
GDP-L-fucose + beta-D-Galactosyl-R <=> GDP + alpha-L-Fucosyl-1,2-beta-D-galactoside
GDP-mannose + Queuosine in tRNA(Asp) <=> GDP + O-4''-alpha-D-Mannosylqueuosine in tRNA(Asp)
3,4-Dihydroxyphenylacetaldehyde + Dopamine <=> (S)-Norlaudanosoline + H2O
1-Methylnicotinamide + Oxygen + H2O <=> N1-Methyl-4-pyridone-5-carboxamide + Hydrogen peroxide + H+
Toluene-cis-dihydrodiol + NAD+ <=> 2,3-Dihydroxytoluene + NADH + H+
2,3-Dihydroxytoluene + Oxygen <=> 2-Hydroxy-6-keto-2,4-heptadienoate
S-(2-Hydroxyacyl)glutathione + H2O <=> Glutathione + 2-Hydroxy carboxylate
O-Acetyl-L-serine + 3,4-Dihydroxypyridine + H+ <=> 3-(3,4-Dihydroxypyridin-1-yl)-L-alanine + Acetate
3-Dehydrosphinganine + FAD <=> 3-Ketosphingosine + FADH2
Indole-3-acetaldehyde oxime <=> 3-Indoleacetonitrile + H2O
Glucobrassicin + H2O <=> 3-Indoleacetonitrile + D-Glucose + Sulfate + Sulfur
3-Methylbutanoyl-CoA + FAD <=> 3-Methylcrotonyl-CoA + FADH2
3-Methylbutanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
3alpha-Hydroxyglycyrrhetinate + NADP+ <=> 3-Oxoglycyrrhetinate + NADPH + H+
3-cis-Dodecenoyl-CoA <=> 2-trans-Dodecenoyl-CoA
4-Chlorobenzoyl-CoA + H2O <=> 4-Hydroxybenzoyl-CoA + Cl- + H+
(+)-Bornane-2,5-dione + Reduced FMN + Oxygen <=> 5-Oxo-1,2-campholide + FMN + H2O
Penicillin G + H2O <=> 6-Aminopenicillanate + Phenylacetic acid
Chondroitin <=> Dermatan
Ethyl (R)-3-hydroxyhexanoate + NADP+ <=> Ethyl 3-oxohexanoate + NADPH + H+
Ethyl (S)-3-hydroxyhexanoate + NADP+ <=> Ethyl 3-oxohexanoate + NADPH + H+
UDP-glucose + Hydroxyanthraquinone <=> UDP + Glucosyloxyanthraquinone
Protein N(pi)-phospho-L-histidine + Maltose <=> Protein histidine + Maltose 6'-phosphate
N-Acetylmuramoyl-Ala + H2O <=> N-Acetylmuramate + L-Alanine
N-Benzoyl-D-arginine-4-nitroanilide + H2O <=> N-Benzoyl-D-arginine + 4-Nitroaniline
cis-1,2-Dihydronaphthalene-1,2-diol + NAD+ <=> Naphthalene-1,2-diol + NADH + H+
Naphthalene-1,2-diol + Oxygen <=> 2-Hydroxychromene-2-carboxylate
Oligoglycosylglucosylceramide + H2O <=> Oligoglycosylglucose + N-Acylsphingosine
Phorbol 12,13-dibutanoate + H2O <=> Phorbol 13-butanoate + Butanoic acid
Peptide-L-methionine + Thioredoxin disulfide + H2O <=> Peptide-L-methionine (S)-S-oxide + Thioredoxin
[Protein]-S8-aminomethyldihydrolipoyllysine + Tetrahydrofolate <=> Dihydrolipoylprotein + 5,10-Methylenetetrahydrofolate + Ammonia
ATP + 1-Alkyl-sn-glycerol <=> ADP + 1-Alkyl-sn-glycero-3-phosphate
UDP-glucose + 13-Hydroxydocosanoic acid <=> UDP + 13-beta-D-Glucosyloxydocosanoate
2,6-Dihydroxypyridine + Oxygen + NADH + H+ <=> 2,3,6-Trihydroxypyridine + NAD+ + H2O
2-Oxohept-3-enedioate + H2O <=> 4-Hydroxy-2-oxo-heptanedioate
2-Oxohept-3-enedioate + H2O <=> 2,4-Dihydroxyhept-2-enedioate
5-Carboxy-2-oxohept-3-enedioate <=> 2-Oxohept-3-enedioate + CO2
2-Oxohept-3-enedioate <=> 2-Hydroxyhepta-2,4-dienedioate
3-Hydroxy-L-glutamate <=> 4-Amino-3-hydroxybutanoate + CO2
3-Hydroxybenzyl alcohol + NADP+ <=> 3-Hydroxybenzaldehyde + NADPH + H+
3-Hydroxyisovaleryl-CoA <=> 3-Methylcrotonyl-CoA + H2O
ATP + 3-Methylcrotonyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-Methylglutaconyl-CoA
Lithocholic acid + NAD+ <=> 3-Oxo-5beta-cholanate + NADH + H+
4-Chlorophenylacetonitrile + 2 H2O <=> 4-Chlorophenylacetate + Ammonia
4-Methylumbelliferyl acetate + H2O <=> 4-Methylumbelliferone + Acetate
5-Acetamidopentanoate + NADH + H+ + CO2 <=> 6-Acetamido-2-oxohexanoate + NAD+ + H2O
ATP + 5-Methylthio-D-ribose <=> ADP + S-Methyl-5-thio-D-ribose 1-phosphate
ATP + 5-Phosphoribosylamine + Glycine <=> ADP + Orthophosphate + 5'-Phosphoribosylglycinamide
S-Adenosyl-L-methionine + Cytochrome c L-lysine <=> S-Adenosyl-L-homocysteine + Cytochrome c N6-methyl-L-lysine
Isopenicillin N <=> Penicillin N
Nicotinate D-ribonucleotide + Dimethylbenzimidazole <=> Nicotinate + N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H+
2-Succinylbenzoyl-CoA <=> 1,4-Dihydroxy-2-naphthoate + CoA
(+)-cis-3,4-Dihydrophenanthrene-3,4-diol + NAD+ <=> Phenanthrene-3,4-diol + NADH + H+
2-Aminoethylphosphonate + Pyruvate <=> Phosphonoacetaldehyde + L-Alanine
Dimethylsulfonioacetate + L-Homocysteine <=> S-Methylthioglycolate + L-Methionine + H+
Tetrahydroxypteridine <=> Xanthine-8-carboxylate
ATP + alpha,omega-Dicarboxylic acid + CoA <=> AMP + Diphosphate + omega-Carboxyacyl-CoA
Geranylgeranyl diphosphate + sn-Glycerol 1-phosphate <=> Diphosphate + 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
(5-L-Glutamyl)-peptide + Amino acid <=> Peptide + 5-L-Glutamyl amino acid
(S)-4-Hydroxymandelate <=> (R)-4-Hydroxymandelate
2-Acyl-1-alkyl-sn-glycero-3-phosphate + H2O <=> 1-Alkyl-2-acylglycerol + Orthophosphate
21-Hydroxypregnenolone + NAD+ <=> 11-Deoxycorticosterone + NADH + H+
11-Deoxycorticosterone <=> 20-Hydroxy-3-oxopregn-4-en-21-al
16alpha-Hydroxyprogesterone <=> 16-Dehydroprogesterone + H2O
2-Carboxy-D-arabinitol 1-phosphate + H2O <=> 2-Carboxy-D-arabinitol + Orthophosphate
S-Adenosyl-L-methionine + (E)-2-Methylpropanal oxime <=> S-Adenosyl-L-homocysteine + 2-Methylpropanal O-methyloxime
(S)-3-Hydroxydodecanoyl-CoA <=> 2-trans-Dodecenoyl-CoA + H2O
3-Hydroxy-L-kynurenine + 2-Oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-Glutamate
3-Hydroxy-L-kynurenine <=> 3-Hydroxykynurenamine + CO2
O-Phospho-L-serine + 2-Oxoglutarate <=> 3-Phosphonooxypyruvate + L-Glutamate
6-Acetamido-2-oxohexanoate + H2O <=> Acetate + 6-Amino-2-oxohexanoate
6-Amino-2-oxohexanoate <=> Delta1-Piperideine-2-carboxylate + H2O
2-Hydroxyethylenedicarboxylate <=> Acetylenedicarboxylate + H2O
Coproporphyrinogen III + 3 Oxygen <=> Coproporphyrin III + 3 Hydrogen peroxide
UDP-glucose + D-Mannosylglycoprotein <=> UMP + 6-(D-Glucose-1-phospho)-D-mannosylglycoprotein
6-(D-Glucose-1-phospho)-D-mannosylglycoprotein + H2O <=> D-Glucose 1-phosphate + D-Mannosylglycoprotein
UDP-N-acetyl-D-galactosamine + Globoside <=> UDP + N-Acetyl-D-galactosaminyl-N-Acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
Globoside + N-Acetyl-D-galactosamine <=> N-Acetyl-D-galactosaminyl-N-Acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide + H2O
alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-Acetyl-D-galactosamine <=> Globoside + H2O
(S)-3-(Imidazol-5-yl)lactate + NAD+ <=> Imidazol-5-yl-pyruvate + NADH + H+
(S)-3-(Imidazol-5-yl)lactate + NADP+ <=> Imidazol-5-yl-pyruvate + NADPH + H+
L-Alanine + (S)-Methylmalonate semialdehyde <=> Pyruvate + L-3-Aminoisobutanoate
L-3-Aminoisobutanoate + 2-Oxoglutarate <=> (S)-Methylmalonate semialdehyde + L-Glutamate
N2-Succinyl-L-arginine + 2 H2O <=> N2-Succinyl-L-ornithine + CO2 + 2 Ammonia
S-Adenosyl-L-methionine + Protein L-isoaspartate <=> S-Adenosyl-L-homocysteine + Protein L-isoaspartate methyl ester
alpha-Amino acid ester + H2O <=> alpha-Amino acid + Alcohol
Acetyl-CoA + [alpha-Tubulin]-L-lysine <=> CoA + [alpha-Tubulin]-N6-acetyl-L-lysine
(2,1-beta-D-Fructosyl)n(m) + (2,1-beta-D-Fructosyl)n(n) <=> (2,1-beta-D-Fructosyl)n(m-1) + (2,1-beta-D-Fructosyl)n(n+1)
Sucrose + (2,1-beta-D-Fructosyl)n <=> D-Glucose + (2,1-beta-D-Fructosyl)n
2,3,4,5-Tetrahydrodipicolinate + NAD+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H+
2,3,4,5-Tetrahydrodipicolinate + NADP+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+
(2R,4S)-2,4-Diaminopentanoate + H2O + NAD+ <=> 2-Amino-4-oxopentanoic acid + Ammonia + NADH + H+
(2R,4S)-2,4-Diaminopentanoate + NADP+ + H2O <=> 2-Amino-4-oxopentanoic acid + NADPH + Ammonia + H+
Bis(2-ethylhexyl)phthalate + H2O <=> Mono-(2-ethylhexyl)phthalate + 2-Ethylhexan-1-ol
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA + NAD+ <=> 2-Methylacetoacetyl-CoA + NADH + H+
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA <=> 2-Methylbut-2-enoyl-CoA + H2O
2-Methylbut-2-enoyl-CoA + 13-Hydroxylupanine <=> CoA + 13-(2-Methylcrotonoyl)oxylupanine
3-Phospho-D-erythronate <=> Phosphoenol-4-deoxy-3-tetrulosonate + H2O
ATP + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine <=> ADP + Orthophosphate + Aminoimidazole ribotide
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <=> Aminoimidazole ribotide + CO2
4-Phospho-D-erythronate + NAD+ <=> 2-Oxo-3-hydroxy-4-phosphobutanoate + NADH + H+
Oxalyl-CoA + L-2,3-Diaminopropanoate <=> CoA + 3-(Carboxycarbonylamino)-L-alanine
L-Asparaginyl-tRNA(Asn) + L-Glutamate + Orthophosphate + ADP <=> L-Aspartyl-tRNA(Asn) + L-Glutamine + ATP + H2O
3'-Phosphoadenylyl sulfate + L-Tyrosine methyl ester <=> Adenosine 3',5'-bisphosphate + L-Tyrosine methyl ester 4-sulfate
N-Formimino-L-aspartate <=> 4-Imidazolone-5-acetate + H2O
CTP + N-Glycoloyl-neuraminate <=> Diphosphate + CMP-N-glycoloylneuraminate
Dolichyl diphosphooligosaccharide + Protein asparagine <=> Dolichyl diphosphate + Glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to protein L-asparagine
N2-Succinyl-L-ornithine + 2-Oxoglutarate <=> N-Succinyl-L-glutamate 5-semialdehyde + L-Glutamate
Prephytoene diphosphate <=> Diphosphate + 15-cis-Phytoene
cis-4-Hydroxy-D-proline + Oxygen <=> 1-Pyrroline-4-hydroxy-2-carboxylate + Hydrogen peroxide
dTDP-L-dihydrostreptose + Streptidine 6-phosphate <=> dTDP + O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate
gamma-Oxalocrotonate + H2O <=> 4-Hydroxy-2-oxopentanoate + CO2
2-Methylprop-2-enoyl-CoA + H2O <=> (S)-3-Hydroxyisobutyryl-CoA
(S)-3-Methyl-2-oxopentanoic acid + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
Phosphatidylcholine + Dolichol <=> Acyldolichol + 1-Acyl-sn-glycero-3-phosphocholine
4-Nitroquinoline N-oxide + 2 NADH + 2 H+ <=> 4-Hydroxyaminoquinoline N-oxide + 2 NAD+ + H2O
4-Nitroquinoline N-oxide + 2 NADPH + 2 H+ <=> 4-Hydroxyaminoquinoline N-oxide + 2 NADP+ + H2O
ATP + D-4'-Phosphopantothenate + L-Cysteine <=> AMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine
CTP + D-4'-Phosphopantothenate + L-Cysteine <=> CMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine
D-4-Hydroxyphenylglycine + 2-Oxoglutarate <=> 4-Hydroxyphenylglyoxylate + L-Glutamate
ATP + Deoxy-5-methylcytidylate <=> ADP + 5-Methyldeoxycytidine diphosphate
Propane-1,2-diol 1-phosphate + NAD+ <=> Hydroxyacetone phosphate + NADH + H+
S-Adenosyl-L-methionine + Magnesium protoporphyrin <=> S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester
N-Substituted aminoacyl-tRNA + H2O <=> N-Substituted amino acid + tRNA
Protein lysine + H2O + Oxygen <=> [Protein]-(S)-2-amino-6-oxohexanoate + Ammonia + Hydrogen peroxide
ATP + THF-polyglutamate(n) + L-Glutamate <=> ADP + Orthophosphate + THF-polyglutamate(n+1)
THF-polyglutamate + (n-1) H2O <=> Tetrahydrofolate + (n-1) L-Glutamate
CTP + 2-Aminoethylphosphonate <=> Diphosphate + CMP-2-aminoethylphosphonate
2-Aminoethylphosphonate + Hydrogen peroxide <=> Ethanolamine + Orthophosphate
2-Aminoethylphosphonate <=> (2-Amino-1-hydroxyethyl)phosphonate
2-Aminoethylphosphonate <=> N-Monomethyl-2-aminoethylphosphonate
Phosphonoacetaldehyde + NAD+ + H2O <=> Phosphonoacetate + NADH + H+
2-Aminoethylphosphonate <=> Ciliatocholate
n (R)-3-Hydroxybutanoyl-CoA <=> Poly-beta-hydroxybutyrate + n CoA
Leukotriene E4 + Oxygen + NADPH + H+ <=> 20-Hydroxyleukotriene E4 + NADP+ + H2O
Resveratrol <=> Piceatannol
4-Chlorocatechol + Oxygen <=> 3-Chloro-cis,cis-muconate
2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Chloro-cis,cis-muconate
2,5-Dihydro-5-oxofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate
7alpha-Hydroxycholesterol + NAD+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADH + H+
7alpha-Hydroxycholesterol + NADP+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADPH + H+
CDP-3,6-dideoxy-D-glucose + NADP+ <=> CDP-4-dehydro-3,6-dideoxy-D-glucose + NADPH + H+
CDP-3,6-dideoxy-D-glucose <=> CDP-3,6-dideoxy-D-mannose
ATP + Deoxynucleoside 5'-phosphate <=> ADP + 2'-Deoxyribonucleoside diphosphate
N-Formyl-L-methionylaminoacyl-tRNA + H2O <=> Formate + L-Methionylaminoacyl-tRNA
L-threo-3-Methylaspartate + 2-Oxoglutarate <=> Methyloxaloacetate + L-Glutamate
Methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside + H2O <=> L-Fucose + Methyl beta-D-galactoside
N-Hydroxy-4-acetylaminobiphenyl + N-Hydroxy-4-aminobiphenyl <=> N-Hydroxy-4-aminobiphenyl + N-Acetoxy-4-aminobiphenyl
Dolichyl diphosphooligosaccharide + H2O <=> Oligosaccharide phosphate + Dolichyl phosphate
Peptidylproline (omega=180) <=> Peptidylproline (omega=0)
ATP + RNA 3'-terminal-phosphate <=> AMP + Diphosphate + RNA terminal-2',3'-cyclic-phosphate
cis-3,4-Leucopelargonidin + 2-Oxoglutarate + Oxygen <=> Pelargonidin + Succinate + CO2 + 2 H2O
2-Pyrone-4,6-dicarboxylate + H2O <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
2-Hydroxy-2-hydropyrone-4,6-dicarboxylate + NAD+ <=> 2-Pyrone-4,6-dicarboxylate + NADH + H+
2-Hydroxy-2-hydropyrone-4,6-dicarboxylate + NADP+ <=> 2-Pyrone-4,6-dicarboxylate + NADPH + H+
3-O-Methylgallate + Oxygen <=> 2-Pyrone-4,6-dicarboxylate + Methanol
Carbamoyl phosphate + 3-Hydroxymethyl ceph-3-em-4-carboxylate <=> Orthophosphate + 3-Carbamoyloxymethylcephem
4-Imidazolone-5-propanoate + H2O <=> Formylisoglutamine
4-Imidazolone-5-propanoate + H2O <=> 4-Oxoglutaramate + Formate + Ammonia
6-Lactoyl-5,6,7,8-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+
7,8-Dihydroneopterin 3'-triphosphate <=> 6-Pyruvoyltetrahydropterin + Triphosphate
UDP-N-acetyl-alpha-D-glucosamine + Lysosomal-enzyme D-mannose <=> UMP + Lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose
Quinolinate + 2 H2O + Orthophosphate <=> Iminoaspartate + Glycerone phosphate
Quinolinate + H2O <=> 2-Amino-3-carboxymuconate semialdehyde
2'-Deoxyribonucleoside diphosphate + Thioredoxin disulfide + H2O <=> Ribonucleoside diphosphate + Thioredoxin
UDP-glucose + (S)-4-Hydroxymandelonitrile <=> UDP + Dhurrin
1,2,3,5-Tetrahydroxybenzene + 1,2,3-Trihydroxybenzene <=> 1,2,3,5-Tetrahydroxybenzene + Phloroglucinol
Dopamine + H2O + Oxygen <=> 3,4-Dihydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide
S-Adenosyl-L-methionine + Dopamine <=> S-Adenosyl-L-homocysteine + 3-Methoxytyramine
para-(Dimethylamino)azobenzene + NADP+ + H2O <=> 4-(Dimethylamino)phenylazoxybenzene + NADPH + H+
4-Hydroxyphenylethanol + NAD+ <=> 4-Hydroxyphenylacetaldehyde + NADH + H+
4-Hydroxyphenylacetaldehyde + Dopamine <=> (S)-Norcoclaurine + H2O
(Z)-4-Hydroxyphenylacetaldehyde oxime <=> 4-Hydroxyphenylacetonitrile + H2O
trans-4-Hydroxycyclohexanecarboxylate + NAD+ <=> 4-Oxocyclohexanecarboxylate + NADH + H+
Etiocholanolone + NAD+ <=> 5beta-Androstane-3,17-dione + NADH + H+
Etiocholanolone + NADP+ <=> 5beta-Androstane-3,17-dione + NADPH + H+
Acylglycerone phosphate + Long-chain alcohol <=> O-Alkylglycerone phosphate + Long-chain acid anion
Diphosphate + Microsomal-membrane protein <=> Orthophosphate + O-Phospho-microsomal-membrane protein
N6,N6,N6-Trimethyl-L-lysine + 2 Protein <=> Protein N6,N6,N6-trimethyl-L-lysine + 2 H2O
DNA containing 6-O-methylguanine + [Protein]-L-cysteine <=> Protein S-methyl-L-cysteine + DNA containing guanine
Deoxynucleoside triphosphate + Thioredoxin disulfide + H2O <=> Ribonucleoside triphosphate + Thioredoxin
Acetyl-CoA + Ribosomal-protein L-alanine <=> CoA + Ribosomal-protein N-acetyl-L-alanine
S-Methyl-3-phospho-1-thio-D-glycerate + H2O <=> S-Methyl-1-thio-D-glycerate + Orthophosphate
Benzylpenicilloic acid <=> Penicillin G + H2O
trans-2,3-Dehydroacyl-CoA + NADP+ <=> (2E,4E)-2,4-Dienoyl-CoA + NADPH + H+
Pectate + H2O <=> Pectate + D-Galacturonate
CDP-choline + 1-Alkyl-2-acetyl-sn-glycerol <=> CMP + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine
UDP-alpha-D-galactose + 2-(2-Hydroxyacyl)sphingosine <=> UDP + 1-(beta-D-Galactosyl)-2-(2-hydroxyacyl)sphingosine
2-Amino-3-carboxymuconate semialdehyde <=> 2-Aminomuconate semialdehyde + CO2
10-Formyltetrahydrofolate + 5'-Phosphoribosylglycinamide <=> Tetrahydrofolate + 5'-Phosphoribosyl-N-formylglycinamide
5'-Phosphoribosylglycinamide + 5,10-Methenyltetrahydrofolate + H2O <=> 5'-Phosphoribosyl-N-formylglycinamide + Tetrahydrofolate
2 Juglone + Oxygen <=> 2 3,5-Dihydroxy-1,4-naphthoquinone
Androstan-3alpha,17beta-diol + NAD+ <=> Dihydrotestosterone + NADH + H+
GDP-mannose + N,N'-Diacetylchitobiosyldiphosphodolichol <=> GDP + alpha-D-Mannosylchitobiosyldiphosphodolichol
S-Adenosyl-L-methionine + Glucuronoxylan D-glucuronate <=> S-Adenosyl-L-homocysteine + Glucuronoxylan 4-O-methyl-D-glucuronate
Indole-3-acetyl-beta-1-D-glucoside + myo-Inositol <=> D-Glucose + Indole-3-acetyl-myo-inositol
UDP-alpha-D-galactose + Indole-3-acetyl-myo-inositol <=> UDP + 5-O-(Indol-3-ylacetyl-myo-inositol) D-galactoside
UDP-L-arabinose + Indole-3-acetyl-myo-inositol <=> UDP + Indol-3-ylacetyl-myo-inositol L-arabinoside
L-2-Amino-6-oxoheptanedioate <=> 2,3,4,5-Tetrahydrodipicolinate + H2O
S-(4-Bromophenyl)-L-cysteine + 2-Oxoglutarate <=> 3-[(4-Bromophenyl)sulfanyl]-2-oxopropanoate + L-Glutamate
Thiomorpholine 3-carboxylate + NAD+ <=> 3,4-Dehydrothiomorpholine-3-carboxylate + NADH + H+
Thiomorpholine 3-carboxylate + NADP+ <=> 3,4-Dehydrothiomorpholine-3-carboxylate + NADPH + H+
alpha-N-Peptidyl-L-glutamine + H2O <=> alpha-N-Peptidyl-L-glutamate + Ammonia
UDP-D-galacturonate + Pectate <=> UDP + Pectate
5alpha-Androstan-3beta,17beta-diol + NADP+ <=> Dihydrotestosterone + NADPH + H+
2,4-Dichloro-2,5-dihydro-5-oxofuran-2-acetate <=> 2,4-Dichloro-cis,cis-muconate
2,4-Dioxotetrahydropyrimidine D-ribonucleotide + Diphosphate <=> 5,6-Dihydrouracil + 5-Phospho-alpha-D-ribose 1-diphosphate
5-Methyl-5,6,7,8-tetrahydromethanopterin + Coenzyme M + 2 Sodium cation(side 1) <=> 5,6,7,8-Tetrahydromethanopterin + 2-(Methylthio)ethanesulfonate + 2 Sodium cation(side 2)
Acetyl-CoA + 2-Deoxystreptamine antibiotic <=> CoA + N3-Acetyl-2-deoxystreptamine antibiotic
Bromoxynil + 2 H2O <=> 3,5-Dibromo-4-hydroxybenzoate + Ammonia
L-Mimosine + H2O <=> 3-Hydroxy-4H-pyrid-4-one + Pyruvate + Ammonia
Etiocholanolone + UDP-glucuronate <=> Etiocholan-3alpha-ol-17-one 3-glucuronide + UDP
2-Methoxyestrone + UDP-glucuronate <=> 2-Methoxyestrone 3-glucuronide + UDP
2-Methoxy-17beta-estradiol + UDP-glucuronate <=> 2-Methoxy-estradiol-17beta 3-glucuronide + UDP
Acetyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CO2 + Acyl-carrier protein
Malonyl-CoA + Flavonol 3-O-beta-D-glucoside <=> CoA + Flavonol 3-O-(6-O-malonyl-beta-D-glucoside)
UDP-glucose + Sarsasapogenin <=> UDP + Asparagoside A
1-Alkyl-sn-glycero-3-phosphate + NADP+ <=> O-Alkylglycerone phosphate + NADPH + H+
Acyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-Acyl-1-alkyl-sn-glycero-3-phosphate
1-Alkyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-Alkyl-sn-glycero-3-phosphate + Ethanolamine
Acyl-CoA + 1-Alkyl-2-acetyl-sn-glycerol <=> CoA + 1-O-Alkyl-2-acetyl-3-acyl-sn-glycerol
2,3,4,5-Tetrahydrodipicolinate + Acetyl-CoA + H2O <=> N-Acetyl-L-2-amino-6-oxopimelate + CoA
Succinyl-CoA + 2,3,4,5-Tetrahydrodipicolinate + H2O <=> CoA + N-Succinyl-2-L-amino-6-oxoheptanedioate
4-Nitrophenyl-3-ketovalidamine <=> 4-Nitroaniline + 5-D-(5/6)-5-C-(Hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one
7-Methylguanosine 5'-triphospho-5'-oligonucleotide + H2O <=> 7-Methylguanosine 5'-phosphate + Oligonucleotide 5'-diphosphate
ATP + D-Alanine + Alanyl-poly(glycerolphosphate) <=> ADP + Orthophosphate + D-Alanyl-alanyl-poly(glycerolphosphate)
Benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP+ <=> Benzyl 2-methyl-3-oxobutanoate + NADPH + H+
Homoisocitrate <=> (Z)-But-1-ene-1,2,4-tricarboxylate + H2O
D-myo-Inositol 3,4-bisphosphate + H2O <=> 1D-myo-Inositol 3-phosphate + Orthophosphate
Glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O <=> N-Acetyl-D-glucosamine + Glycoprotein phospho-D-mannose
trans-3-Hydroxy-L-proline <=> 1-Pyrroline-2-carboxylate + H2O
2-Dehydro-3-deoxy-D-xylonate + NAD+ <=> 5-Hydroxy-2,4-dioxopentanoate + NADH
3-(2,3-Dihydroxyphenyl)propanoate + Oxygen <=> 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
3-D-Glucosyl-1,2-diacylglycerol + UDP-glucose <=> Diglucosyldiacylglycerol + UDP
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Diphosphate <=> 5-Amino-4-imidazolecarboxyamide + 5-Phospho-alpha-D-ribose 1-diphosphate
5-Carboxymethyl-2-hydroxymuconate <=> 5-Carboxy-2-oxohept-3-enedioate
5-Carboxy-2-oxohept-3-enedioate <=> 2-Hydroxyhepta-2,4-dienedioate + CO2
4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate <=> 2 5-Dehydro-4-deoxy-D-glucuronate
5-Dehydro-4-deoxy-D-glucuronate <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate
Methanol + Co(I) corrinoid protein <=> Methyl-Co(III) corrinoid protein + H2O
ATP + Holo-[carboxylase] + HCO3- <=> ADP + Orthophosphate + Carboxybiotin-carboxyl-carrier protein
Acetyl-CoA + Carboxybiotin-carboxyl-carrier protein <=> Malonyl-CoA + Holo-[carboxylase]
Diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ <=> Diethyl 2-methyl-3-oxosuccinate + NADPH + H+
ATP + Guanidinoethyl methyl phosphate <=> ADP + N'-Phosphoguanidinoethyl methyl phosphate
Heparosan-N-sulfate D-glucuronate <=> Heparosan-N-sulfate L-iduronate
alpha-Aminoadipoyl-S-acyl enzyme + NADPH + H+ <=> L-2-Aminoadipate 6-semialdehyde + Holo-Lys2 + NADP+
ATP + N-((R)-Pantothenoyl)-L-cysteine <=> ADP + (R)-4'-Phosphopantothenoyl-L-cysteine
Protein N(pi)-phospho-L-histidine + Lactose <=> Protein histidine + Lactose 6'-phosphate
Protein N(pi)-phospho-L-histidine + Salicin <=> Protein histidine + Salicin 6-phosphate
S-Adenosyl-L-methionine + 1,4-alpha-D-Glucooligosaccharide <=> S-Adenosyl-L-homocysteine + Oligosaccharide containing 6-methyl-D-glucose units
2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + 2 H2O <=> Acetate + 2-(Hydroxymethyl)-4-oxobutanoate + Ammonia + CO2
S-Adenosyl-L-methionine + Gossypetin <=> S-Adenosyl-L-homocysteine + Corniculatusin
4-Carboxy-4-hydroxy-2-oxoadipate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate + H2O
ATP + [Isocitrate dehydrogenase (NADP+)] <=> ADP + [Isocitrate dehydrogenase (NADP+)] phosphate
ATP + Low-density lipoprotein L-serine <=> ADP + Low-density lipoprotein O-phospho-L-serine
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 4-phosphate + Orthophosphate
5-Methyltetrahydropteroyltri-L-glutamate + L-Homocysteine <=> Tetrahydropteroyltri-L-glutamate + L-Methionine
trans-Cinnamoyl beta-D-glucoside + Methanol <=> Methyl cinnamate + D-Glucose
trans-Cinnamoyl beta-D-glucoside + Ethanol <=> Ethyl cinnamate + D-Glucose
trans-Cinnamoyl beta-D-glucoside + Alcohol <=> Alkyl cinnamate + D-Glucose
(6S,9R)-Vomifoliol + NAD+ <=> Dehydrovomifoliol + NADH + H+
Acyl-CoA + 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine <=> CoA + O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <=> cis-Dec-3-enoyl-[acp] + H2O
2-Hydroxy-5-carboxymethylmuconate semialdehyde + NAD+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADH + H+
2-Hydroxy-5-carboxymethylmuconate semialdehyde + NADP+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADPH + H+
S-Methyl-5-thio-D-ribose 1-phosphate <=> S-Methyl-5-thio-D-ribulose 1-phosphate
S-Adenosyl-L-methionine + N-Benzoyl-4-hydroxyanthranilate <=> S-Adenosyl-L-homocysteine + N-Benzoyl-4-methoxyanthranilate
alpha-D-Aldosyl beta-D-fructoside + D-Aldose <=> D-Aldose + alpha-D-Aldosyl beta-D-fructoside
UDP-N-acetyl-D-galactosamine + alpha-L-Fucosyl-1,2-beta-D-galactoside <=> UDP + N-Acetyl-alpha-D-galactosaminyl-(1,3)-[alpha-L-fucosyl-(1,2)]-D-galactoside
2-Methylcitrate <=> (Z)-But-2-ene-1,2,3-tricarboxylate + H2O
(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate <=> (Z)-But-2-ene-1,2,3-tricarboxylate + H2O
(2R,3S)-3-Isopropylmalate + NAD+ <=> (2S)-2-Isopropyl-3-oxosuccinate + NADH + H+
S-Adenosyl-L-methionine + Zymosterol <=> S-Adenosyl-L-homocysteine + Fecosterol
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] <=> But-2-enoyl-[acyl-carrier protein] + H2O
Butyryl-[acp] + NAD+ <=> But-2-enoyl-[acyl-carrier protein] + NADH + H+
Butyryl-[acp] + NADP+ <=> But-2-enoyl-[acyl-carrier protein] + NADPH + H+
UDP-alpha-D-galactose + D-Galactosyl-(1->4)-beta-D-glucosyl-R <=> UDP + D-Galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R
N-Acetylneuraminate 9-phosphate + Orthophosphate <=> N-Acetyl-D-mannosamine 6-phosphate + Phosphoenolpyruvate + H2O
S-Adenosyl-L-methionine + N,N-Dimethylhistidine <=> S-Adenosyl-L-homocysteine + Hercynine
dTDP-4-amino-4,6-dideoxy-D-galactose + 2-Oxoglutarate <=> dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate
(R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Acetolactate + NADPH + H+
(R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid + NADPH + H+
(R)-2,3-Dihydroxy-3-methylbutanoate <=> 3-Methyl-2-oxobutanoic acid + H2O
L-1-Pyrroline-3-hydroxy-5-carboxylate + H2O <=> L-4-Hydroxyglutamate semialdehyde
L-1-Pyrroline-3-hydroxy-5-carboxylate + NAD+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADH + H+
L-1-Pyrroline-3-hydroxy-5-carboxylate + NADP+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADPH + H+
1-Pyrroline-4-hydroxy-2-carboxylate + H2O <=> 2-Oxo-4-hydroxy-5-aminovalerate
1-Pyrroline-4-hydroxy-2-carboxylate <=> Pyrrole-2-carboxylate + H2O
ATP + 5-(2-Hydroxyethyl)-4-methylthiazole <=> ADP + 4-Methyl-5-(2-phosphooxyethyl)thiazole
ATP + Acetate + Holo-[citrate (pro-3S)-lyase] <=> AMP + Diphosphate + Acetyl-[citrate (pro-3S)-lyase]
Acetyl-[citrate (pro-3S)-lyase] + H2O <=> Holo-[citrate (pro-3S)-lyase] + Acetate
UDP-N-acetyl-alpha-D-glucosamine + Estradiol-17alpha 3-D-glucuronoside <=> UDP + 17alpha-(N-Acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Acetate
4-Carboxy-2-hydroxymuconate semialdehyde + NADP+ + H2O <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate + NADPH + H+
5,10-Methenyltetrahydromethanopterin + Hydrogen <=> 5,10-Methylenetetrahydromethanopterin + H+
5,10-Methylenetetrahydromethanopterin + Coenzyme F420 + H+ <=> 5,10-Methenyltetrahydromethanopterin + Reduced coenzyme F420
5-Amino-6-(1-D-ribitylamino)uracil + L-3,4-Dihydroxybutan-2-one 4-phosphate <=> 6,7-Dimethyl-8-(D-ribityl)lumazine + 2 H2O + Orthophosphate
6,7-Dimethyl-8-(D-ribityl)lumazine <=> 7-Hydroxy-6-methyl-8-ribityllumazine
Variant-surface-glycoprotein 1,2-dimyristyl-sn-phosphatidylinositol <=> Soluble variant-surface-glycoprotein + 1,2-Dimyristyl-sn-glycerol
1,2-Bis(3,4-dimethoxyphenyl)propane-1,3-diol + Hydrogen peroxide <=> Veratraldehyde + 1-(3,4-Dimethoxyphenyl)ethane-1,2-diol + H2O
ATP + 5'-Phosphoribosyl-N-formylglycinamide + L-Glutamine + H2O <=> ADP + Orthophosphate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine + L-Glutamate
5,10-Methylenetetrahydromethanopterin + Reduced coenzyme F420 <=> 5-Methyl-5,6,7,8-tetrahydromethanopterin + Coenzyme F420
Acetyl-CoA + Heparan sulfate alpha-D-glucosaminide <=> CoA + Heparan sulfate N-acetyl-alpha-D-glucosaminide
N6-Acetyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Acetyl-L-2-amino-6-oxopimelate + L-Glutamate
1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-alpha-D-galactose <=> Digalactosyl-diacylglycerol + UDP
Digalactosyl-diacylglycerol + H2O <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + D-Galactose
3-beta-D-Galactosyl-sn-glycerol + 2 Fatty acid <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O
2 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> 1,2-Diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 1,2-Diacyl-sn-glycerol
Acyl-[acyl-carrier protein] + 2-Acyl-3-O-(beta-D-galactosyl)-sn-glycerol <=> Acyl-carrier protein + 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol
2 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> 2-Acyl-3-O-(beta-D-galactosyl)-sn-glycerol + Acyl1-monogalactosyl-diacylglycerol
N-Succinyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Succinyl-2-L-amino-6-oxoheptanedioate + L-Glutamate
3'-Phosphoadenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate <=> Adenosine 3',5'-bisphosphate + UDP-N-acetyl-D-galactosamine 4,6-bissulfate
UDP-N-acetyl-D-mannosaminouronate + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> N-Acetyl-beta-D-mannosaminuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP
4-Carboxy-4-hydroxy-2-oxoadipate <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate + H2O
1-(5-Phosphoribosyl)imidazole-4-acetate + H2O <=> (1-Ribosylimidazole)-4-acetate + Orthophosphate
Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA
S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine
4-Carboxy-2-oxo-3-hexenedioate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NAD+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + CO2 + NADH + H+
Acetyl-CoA + alpha-2,8-Linked polymer of sialic acid <=> CoA + Polysialic acid acetylated at O-7
Glycodeoxycholate + H2O <=> Deoxycholic acid + Glycine
Taurodeoxycholate + H2O <=> Deoxycholic acid + Taurine
4-Carboxy-2-hydroxymuconate semialdehyde + H2O <=> 4-Methylene-2-oxoglutarate + Formate
2-Hydroxy-2-hydropyrone-4,6-dicarboxylate <=> 4-Carboxy-2-hydroxymuconate semialdehyde
5-(4-Acetoxybut-1-ynyl)-2,2'-bithiophene + H2O <=> 5-(4-Hydroxybut-1-ynyl)-2,2'-bithiophene + Acetate
UDP-glucose + 5-(D-Galactosyloxy)-L-lysine-procollagen <=> UDP + 1,2-D-Glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen
UDP-N-acetyl-alpha-D-glucosamine + Lactosylceramide <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-D-glucosaminyldiphosphodolichol <=> UDP + N,N'-Diacetylchitobiosyldiphosphodolichol
UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-glycopeptide <=> UDP + beta-D-Galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide
S-Adenosyl-L-methionine + Protein C-terminal S-farnesyl-L-cysteine <=> S-Adenosyl-L-homocysteine + Protein C-terminal S-farnesyl-L-cysteine methyl ester
1-O-Galloyl-beta-D-glucose + 1,2,3,6-Tetrakis-O-galloyl-beta-D-glucose <=> D-Glucose + Pentagalloylglucose
2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <=> cis-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid
GDP-mannose + N,N'-Diacetylchitobiosyldiphosphodolichol <=> GDP + beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol
Protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine + H2O <=> D-Glucose + Protein beta-D-galactosyl-L-hydroxylysine
1-Phosphatidyl-1D-myo-inositol 3-phosphate + 2 ATP <=> Phosphatidylinositol-3,4,5-trisphosphate + 2 ADP
S-Adenosyl-L-methionine + Tomentin <=> S-Adenosyl-L-homocysteine + Chrysosplenol D + H+
3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + NAD+ + H2O <=> 3alpha,7alpha-Dihydroxy-5beta-cholestanate + NADH + H+
ATP + 3alpha,7alpha-Dihydroxy-5beta-cholestanate + CoA <=> AMP + Diphosphate + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
ATP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine <=> ADP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate
4-Methylmuconolactone <=> 3-Methylmuconolactone
3-D-Glucuronosyl-N2,6-disulfo-beta-D-glucosamine + H2O <=> N,6-O-Disulfo-D-glucosamine + D-Glucuronate
Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + Orthophosphate
Phosphatidylcholine + Retinol-(cellular-retinol-binding-protein) <=> 2-Acyl-sn-glycero-3-phosphocholine + Retinyl-ester-(cellular-retinol-binding-protein)
(4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + H2O <=> L-Xylonate + CO2
(15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NAD+ <=> 15-OxoETE + NADH + H+
(15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NADP+ <=> 15-OxoETE + NADPH + H+
Geranylgeranyl diphosphate + 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate <=> Diphosphate + 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
DDT <=> 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + Hydrochloric acid
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + Oxygen <=> 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide + NADP+ + H2O
3-Hydroxy-2-methylpyridine-4,5-dicarboxylate + NADH + H+ <=> 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate + H2O + NAD+
5-(3,4-Diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O <=> 5-(3-Hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + Acetate
UDP-apiose + Apigenin 7-O-beta-D-glucoside <=> UDP + Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]
Peptide beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-L-serine + H2O <=> beta-D-Galactosyl-(1->3)-N-acetyl-D-galactosamine + [Protein]-L-serine
UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + 2-Oxoglutarate <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-Glutamate
UDP-alpha-D-galactose + N-Acetyllactosamine <=> UDP + alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosamine
CMP-N-acetylneuraminate + N-Acetyllactosamine <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=> Acetoacetyl-[acp] + NADPH + H+
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxodecanoyl-[acp] + NADPH
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <=> trans-Dec-2-enoyl-[acp] + H2O
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxooctanoyl-[acp] + NADPH + H+
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] <=> trans-Oct-2-enoyl-[acp] + H2O
(E)-2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide <=> (Z)-2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide
Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Dihydromethanophenazine <=> Coenzyme B + Coenzyme M + Methanophenazine
Coenzyme B + 2-(Methylthio)ethanesulfonate <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Methane
[Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O <=> [Hydroxymethylglutaryl-CoA reductase (NADPH)] + Orthophosphate
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexadecanoyl-[acp] + NADPH + H+
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] <=> trans-Hexadec-2-enoyl-[acp] + H2O
ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate
Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
UDP-alpha-D-galactose + alpha-L-Fucosyl-1,2-beta-D-galactoside <=> UDP + alpha-D-Galactosyl-(1,3)-[alpha-L-fucosyl-(1,2)]-D-galactoside
UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + H2O <=> UMP + Lipid X
UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <=> UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + Acyl-carrier protein
Alprostadil + NADP+ <=> (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+
GDP-L-fucose + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-R <=> GDP + 1,3-beta-D-Galactosyl-(alpha-1,4-L-fucosyl)-N-acetyl-D-glucosaminyl-R
ATP + [Hydroxymethylglutaryl-CoA reductase (NADPH)] <=> ADP + [Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate
(5Z)-11alpha-Hydroxy-9,15-dioxoprostanoate + NAD+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+
(5Z)-11alpha-Hydroxy-9,15-dioxoprostanoate + NADP+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate + NADPH + H+
N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + L-Glutamine <=> D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + L-Glutamate
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <=> Fumarate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
ATP + Biotin + Apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [Acetyl-CoA:carbon-dioxide ligase (ADP-forming)]
ATP + Biotin + Apo-[methylmalonyl-CoA:pyruvate carboxytransferase] <=> AMP + Diphosphate + [Methylmalonyl-CoA:pyruvate carboxytransferase]
CMP-N-acetylneuraminate + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R
(13E)-(15S)-15-Hydroxy-9-oxoprosta-10,13-dienoate <=> (13E)-(15S)-15-Hydroxy-9-oxoprosta-11,13-dienoate
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxotetradecanoyl-[acp] + NADPH + H+
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetyl-alpha-D-glucosamine <=> Acyl-carrier protein + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <=> trans-Tetradec-2-enoyl-[acp] + H2O
3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + Oxygen + NADPH + H+ <=> 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + NADP+
ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> UDP + beta-D-Galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R
cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide <=> trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide
UDP-glucose + Nuatigenin <=> UDP + Nuatigenin 3beta-D-glucopyranoside
1,6,6-Trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one <=> 4,5-Dihydro-5,5-dimethyl-4-(3-oxobutyl)furan-2(3H)-one
UDP-glucose + DIMBOA <=> UDP + DIMBOA-glucoside
ATP + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + CoA <=> AMP + Diphosphate + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA
CDP-abequose + alpha-D-Mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol <=> CDP + alpha-D-Abequosyl-(1->3)-alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol
ATP + Biotin + Apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [Propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
CMP-N-acetylneuraminate + GM3 <=> CMP + GD3
UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> GM3 + N-Acetyl-D-galactosamine
UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O <=> UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + Acetate
S-Acetylphosphopantetheine + Holo-[citrate (pro-3S)-lyase] <=> Pantetheine 4'-phosphate + Acetyl-[citrate (pro-3S)-lyase]
CMP-N-acetylneuraminate + beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R
ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate <=> 5-Pyridoxolactone + H2O
N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H2O <=> alpha-Ribazole + Orthophosphate
CMP-N-acetylneuraminate + beta-D-Galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein
3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + Oxygen <=> 3-Hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate
Stizolobate + NADH + H+ <=> 4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NAD+
Stizolobate + NADPH + H+ <=> 4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+
Stizolobinate + NADH + H+ <=> 5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NAD+
Stizolobinate + NADPH + H+ <=> 5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+
5-Amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone + Oxygen <=> 5-Amino-4-chloro-2-(5-hydroxymuconoyl)-3(2H)-pyridazinone
UDP-N-acetyl-D-galactosamine + D-Glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan <=> UDP + N-Acetyl-beta-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan
ATP + Biotin + Apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)]
UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + Lipid X <=> UDP + Lipid A disaccharide
UDP-glucuronate + 3-beta-D-Galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein <=> UDP + 3-beta-D-Glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein
Juvenile hormone II + H2O <=> Juvenile hormone II acid + Methanol
(5Z,9E,14Z)-(8xi,11R,12S)-11,12-Epoxy-8-hydroxyicosa-5,9,14-trienoic acid + H2O <=> (5Z,9E,14Z)-(8xi,11xi,12S)-8,11,12-Trihydroxyicosa-5,9,14-trienoate
UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide
UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + H2O <=> UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanine + D-Alanine
UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + N-Acetyl-D-galactosaminyl-1,4-beta-N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide
20-OH-Leukotriene B4 <=> 20-COOH-Leukotriene B4
Malonyl-CoA + Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside] <=> CoA + Malonylapiin
UDP-N-acetyl-alpha-D-glucosamine + 1,3-alpha-D-Mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose <=> UDP + 1,3-alpha-D-Mannosyl-(1,2-N-acetyl-alpha-D-glucosaminyl)-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose
7,8-Dihydroneopterin 3'-triphosphate + 3 H2O <=> 7,8-Dihydroneopterin + 3 Orthophosphate
7,8-Dihydroneopterin + Orthophosphate <=> Dihydroneopterin phosphate + H2O
(+/-)-5-[(tert-Butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+ <=> (+/-)-5-[(tert-Butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH + H+
CMP-N-acetylneuraminate + GA2 <=> CMP + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
UDP-alpha-D-galactose + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> UDP + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
CMP-N-acetylneuraminate + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GD2
D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + D-Galactose
N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> GA2 + N-Acetylneuraminate
CMP-N-acetylneuraminate + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactose-1,3-(alpha-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R
7,8-Dihydroneopterin 3'-triphosphate + H2O <=> Dihydroneopterin phosphate + Diphosphate
7,8-Dihydroneopterin 3'-triphosphate + H2O <=> 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine
5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide <=> N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2)-(N-acetyl-beta-D-glucosaminyl-1,4)-alpha-D-mannosyl-R
3'-Phosphoadenylyl sulfate + alpha-D-Glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol <=> Adenosine 3',5'-bisphosphate + 6-Sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol
1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + GDP-L-fucose <=> Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + GDP
CMP-N-acetylneuraminate + GA1 <=> CMP + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GD1b
D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + N-Acetylneuraminate <=> N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O
UDP-N-acetyl-alpha-D-glucosamine + alpha-D-Mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
CMP-N-acetylneuraminate + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide
ATP + Lipid A disaccharide <=> ADP + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate + CMP-3-deoxy-D-manno-octulosonate <=> 3-Deoxy-D-manno-octulosonyl-lipid IV(A) + CMP
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2 <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-beta-D-mannosyl-R
UDP-N-acetyl-alpha-D-glucosamine + 6-(2-[N-Acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R <=> UDP + 6-(2,6-Bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
(R)-3-Ureidoisobutyrate + H2O <=> (R)-3-Amino-2-methylpropanoate + CO2 + Ammonia
24,25-Dihydrolanosterol + NADPH <=> 4alpha-Methylcholesta-8-en-3beta-ol + NADP+
4alpha-Methylcholesta-8-en-3beta-ol <=> Methostenol
(S)-2-Acetolactate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + Pyruvate
2-Oxobutanoate + 2-(alpha-Hydroxyethyl)thiamine diphosphate <=> (S)-2-Aceto-2-hydroxybutanoate + Thiamin diphosphate
N-Methylhistamine + H2O + Oxygen <=> Methylimidazole acetaldehyde + Ammonia + Hydrogen peroxide
16alpha-Hydroxyandrost-4-ene-3,17-dione + H+ + NADH <=> 16alpha-Hydroxydehydroepiandrosterone + NAD+
Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H+
Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+
UDP-glucuronate + Estriol <=> UDP + 16-Glucuronide-estriol
Aminoacyl-tRNA + Phosphatidylglycerol <=> Aminoacyl-phosphatidylglycerol + tRNA
Aminoacyl-tRNA + Peptidyl-tRNA <=> tRNA + Peptidyl-aminoacyl-tRNA
trans-beta-D-Glucosyl-2-hydroxycinnamate <=> cis-beta-D-Glucosyl-2-hydroxycinnamate
(2R,5S)-2,5-Diaminohexanoate + H2O + NAD+ <=> 2-Amino-5-oxohexanoate + Ammonia + NADH + H+
(2R,5S)-2,5-Diaminohexanoate + H2O + NADP+ <=> 2-Amino-5-oxohexanoate + Ammonia + NADPH + H+
Stylopine + S-Adenosyl-L-methionine <=> (S)-cis-N-Methylstylopine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + (S)-Coclaurine <=> S-Adenosyl-L-homocysteine + (S)-N-Methylcoclaurine + H+
(R)-Reticuline + NADP+ <=> 1,2-Dehydroreticuline + NADPH
Salutaridinol + NADP+ <=> Salutaridine + NADPH + H+
6-Hydroxyprotopine <=> Dihydrosanguinarine + 2 H2O
Dihydrosanguinarine + Oxygen + H+ <=> Sanguinarine + Hydrogen peroxide
S-Adenosyl-L-methionine + 12-Hydroxydihydrochelirubine <=> S-Adenosyl-L-homocysteine + Dihydromacarpine + H+
Dihydrochelirubine + Oxygen + H+ <=> Chelirubine + Hydrogen peroxide
S-Adenosyl-L-methionine + 10-Hydroxydihydrosanguinarine <=> S-Adenosyl-L-homocysteine + Dihydrochelirubine + H+
S-Adenosyl-L-methionine + 3-Hexaprenyl-4,5-dihydroxybenzoate <=> S-Adenosyl-L-homocysteine + 3-Hexaprenyl-4-hydroxy-5-methoxybenzoate + H+
S-Adenosyl-L-methionine + (R,S)-Tetrahydrobenzylisoquinoline <=> S-Adenosyl-L-homocysteine + N-Methyl-(R,S)-tetrahydrobenzylisoquinoline + H+
S-Adenosyl-L-methionine + 6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + Nororientaline + H+
S-Adenosyl-L-methionine + Tetrahydropapaveroline <=> S-Adenosyl-L-homocysteine + 6-O-Methylnorlaudanosoline + H+
S-Adenosyl-L-methionine + (S)-Tetrahydroprotoberberine <=> S-Adenosyl-L-homocysteine + cis-N-Methyl-(S)-7,8,13,14-tetrahydroprotoberberine
S-Adenosyl-L-methionine + [Cytochrome c] methionine <=> S-Adenosyl-L-homocysteine + [Cytochrome c] S-methylmethionine
S-Adenosyl-L-methionine + Histone L-arginine <=> S-Adenosyl-L-homocysteine + Histone N(omega)-methyl-L-arginine
S-Adenosyl-L-methionine + [Myeline basic protein] L-arginine <=> S-Adenosyl-L-homocysteine + [Myeline basic protein] N(omega)-methyl-L-arginine
1-Alkyl-2-arachidonyl-sn-glycero-3-phosphocholine + 1-Alkyl-2-lyso-sn-glycero-3-phosphoethanolamine <=> 1-Alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine
1-Radyl-2-acyl-sn-glycero-3-phosphocholine + 1-Alkyl-2-lyso-sn-glycero-3-phosphoethanolamine <=> 1-Alkyl-2-acylglycerophosphoethanolamine + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine
2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine + 1-Organyl-2-lyso-sn-glycero-3-phospholipid <=> 1-Radyl-2-acetyl-sn-glycero-3-phospholipid + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine
Acetyl-CoA + Salutaridinol <=> CoA + 7-O-Acetylsalutaridinol
Dodecanoyl-[acyl-carrier protein] + NAD+ <=> trans-Dodec-2-enoyl-[acp] + NADH + H+
Dodecanoyl-[acyl-carrier protein] + NADP+ <=> trans-Dodec-2-enoyl-[acp] + NADPH + H+
Dodecanoyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> 3-Oxotetradecanoyl-[acp] + CO2 + Acyl-carrier protein
N-Acetylarylalkylamine + H2O <=> Arylalkylamine + Acetate
Phaseollidin hydrate <=> Phaseollidin + H2O
(2S)-2-Methylacyl-CoA <=> (2R)-2-Methylacyl-CoA
ATP + Detyrosinated alpha-tubulin + L-Tyrosine <=> alpha-Tubulin + ADP + Orthophosphate
5-Aminoimidazole + H2O <=> Imidazolone + Ammonia
5-Aminoimidazole + CO2 <=> 5-Amino-4-imidazole carboxylate
UTP + [Protein-PII] <=> Diphosphate + Uridylyl-[protein-PII]
4a-Hydroxytetrahydrobiopterin <=> Dihydrobiopterin + H2O
L-Lysine 1,6-lactam <=> D-2-Aminohexano-6-lactam
(S)-3-Hydroxyhexadecanoyl-CoA + NAD+ <=> 3-Oxopalmitoyl-CoA + NADH + H+
(S)-3-Hydroxyhexadecanoyl-CoA <=> trans-Hexadec-2-enoyl-CoA + H2O
(S)-3-Hydroxytetradecanoyl-CoA + NAD+ <=> 3-Oxotetradecanoyl-CoA + NADH
(S)-3-Hydroxytetradecanoyl-CoA <=> trans-Tetradec-2-enoyl-CoA + H2O
(S)-3-Hydroxydodecanoyl-CoA + NAD+ <=> 3-Oxododecanoyl-CoA + NADH + H+
Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA
(S)-Hydroxydecanoyl-CoA + NAD+ <=> 3-Oxodecanoyl-CoA + NADH + H+
(S)-Hydroxydecanoyl-CoA <=> trans-Dec-2-enoyl-CoA + H2O
(S)-3-Hydroxyoctanoyl-CoA + NAD+ <=> 3-Oxooctanoyl-CoA + NADH + H+
(S)-3-Hydroxyoctanoyl-CoA <=> trans-Oct-2-enoyl-CoA + H2O
Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA
(S)-Hydroxyhexanoyl-CoA + NAD+ <=> 3-Oxohexanoyl-CoA + NADH + H+
(S)-Hydroxyhexanoyl-CoA <=> trans-Hex-2-enoyl-CoA + H2O
Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
Decanoyl-CoA + NADP+ <=> trans-Dec-2-enoyl-CoA + NADPH + H+
Decanoyl-CoA + FAD <=> trans-Dec-2-enoyl-CoA + FADH2
cis,cis-3,6-Dodecadienoyl-CoA <=> trans,cis-Lauro-2,6-dienoyl-CoA
11beta-Hydroxyandrost-4-ene-3,17-dione + NADP+ <=> Adrenosterone + NADPH + H+
2-Hydroxyestrone + S-Adenosyl-L-methionine <=> 2-Methoxyestrone + S-Adenosyl-L-homocysteine
Desmosterol + S-Adenosyl-L-methionine <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + S-Adenosyl-L-homocysteine
2-Hydroxyestradiol + S-Adenosyl-L-methionine <=> 2-Methoxy-17beta-estradiol + S-Adenosyl-L-homocysteine
Dihydromacarpine + Oxygen + H+ <=> Macarpine + Hydrogen peroxide
7-O-Acetylsalutaridinol <=> Thebaine + Acetate
L-Selenomethionine + H2O <=> Methaneselenol + Ammonia + 2-Oxobutanoate
ATP + L-Selenomethionine + H2O <=> Orthophosphate + Diphosphate + Se-Adenosylselenomethionine
S-Adenosyl-L-methionine + L-Selenomethionine <=> S-Adenosyl-L-homocysteine + Se-Methylselenomethionine
L-Selenomethionine <=> Selenomethionine Se-oxide
L-Glutamate + 4-Hydroxyphenylacetyl-CoA <=> CoA + 4-Hydroxyphenylacetylglutamic acid
4-Hydroxyphenylacetyl-CoA + Glycine <=> p-Hydroxyphenylacetylglycine + CoA
ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate
beta-D-Fructose 1,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate
4-Carboxy-4-hydroxy-2-oxoadipate <=> 4-Carboxy-2-oxo-3-hexenedioate + H2O
3-Ketolactose + H2O <=> 3-Keto-beta-D-galactose + beta-D-Glucose
(4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + H2O <=> L-Lyxonate + CO2
Dehydroascorbate + H2O <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
5-Cholestene + Oxygen + NADPH + H+ <=> 5,6beta-Epoxy-5beta-cholestane + NADP+ + H2O
5-Cholestene + NADPH + Oxygen + H+ <=> 5,6alpha-Epoxy-5alpha-cholestane + NADP+ + H2O
5,6beta-Epoxy-5beta-cholestane + H2O <=> 5alpha-Cholestan-5alpha,6beta-diol
Cholesterol-5beta,6beta-epoxide + H2O <=> 3beta,5alpha,6beta-Cholestanetriol
5,6alpha-Epoxy-5alpha-cholestane + H2O <=> 5alpha-Cholestan-5alpha,6beta-diol
Phytyl diphosphate + Chlorophyllide <=> Bacteriopheophytin + Magnesium cation + Diphosphate
all-trans-Neurosporene <=> beta-Zeacarotene
Zymosterol <=> 5alpha-Cholesta-7,24-dien-3beta-ol
3alpha,7alpha,26-Trihydroxy-5beta-cholestane + NAD+ <=> 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + NADH + H+
3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane <=> 5beta-Cyprinolsulfate
(24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + H2O <=> (24R,25R)-3alpha,7alpha,24-Trihydroxy-5beta-cholestanoyl-CoA
(24R,25R)-3alpha,7alpha,24-Trihydroxy-5beta-cholestanoyl-CoA + NAD+ <=> 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA + NADH + H+
Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA
(24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA + NAD+ <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA + NADH + H+
(24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + H2O
7alpha-Hydroxy-5beta-cholestan-3-one + NADP+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADPH + H+
3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ <=> 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+
3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ <=> 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+
7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADP+ <=> 4-Cholesten-7alpha,12alpha-diol-3-one + NADPH + H+
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + NAD+ <=> 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADH + H+
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + NADP+ <=> 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADPH + H+
Tetrahydrocortisone + NAD+ <=> 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADH + H+
17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + H+ + NADPH <=> Tetrahydrocortisone + NADP+
Cortolone + NAD+ <=> Tetrahydrocortisone + NADH + H+
Urocortisol + NAD+ <=> Dihydrocortisol + NADH + H+
Urocortisol + NADP+ <=> Dihydrocortisol + NADPH + H+
Cortol + NAD+ <=> Urocortisol + NADH + H+
3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al + NAD+ <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADH + H+
3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al + NADP+ <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADPH + H+
Tetrahydrocorticosterone + NAD+ <=> 11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADH + H+
Tetrahydrocorticosterone + NADP+ <=> 11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADPH + H+
Tetrahydrocorticosterone + NADP+ <=> 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADPH + H+
3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NAD+ <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione + NADH + H+
3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADP+ <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione + NADPH + H+
3alpha,20alpha,21-Trihydroxy-5beta-pregnan-11-one + NAD+ <=> 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADH + H+
Pregnanolone + NAD+ <=> 5beta-Pregnane-3,20-dione + NADH + H+
Pregnanolone + NADP+ <=> 5beta-Pregnane-3,20-dione + NADPH + H+
Pregnanediol + NAD+ <=> Pregnanolone + NADH + H+
11-Deoxycortisol + H+ + NADH <=> 17alpha,21-Dihydroxypregnenolone + NAD+
Sulfatide + H2O <=> Galactosylceramide + Sulfate
5-Ureido-4-imidazole carboxylate + H2O <=> 5-Amino-4-imidazole carboxylate + Ammonia + CO2
S-Adenosyl-L-methionine + DNA cytosine <=> S-Adenosyl-L-homocysteine + 5-Methylcytosine in DNA
O-Acetyl-L-serine + Thiosulfate + Thioredoxin + H+ <=> L-Cysteine + Sulfite + Thioredoxin disulfide + Acetate
S-Glutathionyl-L-cysteine + Sulfate <=> S-Sulfo-L-cysteine + Glutathione
3-Sulfinylpyruvate + H2O <=> Sulfite + Pyruvate
Homoisocitrate + NAD+ <=> Oxaloglutarate + NADH + H+
L-2-Aminoadipate adenylate + Holo-Lys2 <=> alpha-Aminoadipoyl-S-acyl enzyme + AMP
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine
S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine
Isopenicillin N + Phenylacetyl-CoA + H2O <=> Penicillin G + L-2-Aminoadipate + CoA
Biocytin + 2 Peptide <=> Holo-[carboxylase] + 2 H2O
L-2-Aminoadipate + L-Valine + L-Cysteine + 3 ATP + H2O <=> delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine + 3 AMP + 3 Diphosphate
delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine + Oxygen <=> Isopenicillin N + 2 H2O
Imidazol-5-yl-pyruvate <=> Imidazole-4-acetaldehyde + CO2
Hydantoin-5-propionate + H2O <=> N-Carbamyl-L-glutamate
Imidazol-5-yl-pyruvate + NADH + H+ <=> Imidazole lactate + NAD+
Ergothioneine <=> Thiourocanic acid + Trimethylamine
Ergothioneine <=> Hercynine
Formylisoglutamine + H2O <=> Isoglutamine
3,4-Dihydroxyphenylethyleneglycol + NAD+ <=> 3,4-Dihydroxymandelaldehyde + NADH + H+
S-Adenosyl-L-methionine + 3,4-Dihydroxyphenylethyleneglycol <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4-hydroxyphenylethyleneglycol
3,4-Dihydroxymandelaldehyde + NAD+ + H2O <=> 3,4-Dihydroxymandelate + NADH + H+
3,4-Dihydroxymandelaldehyde + NADP+ + H2O <=> 3,4-Dihydroxymandelate + NADPH + H+
2 5,6-Dihydroxyindole + Oxygen <=> 2 Indole-5,6-quinone + 2 H2O
5,6-Dihydroxyindole + CO2 <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
Indole-5,6-quinone + Oxygen <=> Eumelanin + H2O
S-Adenosyl-L-methionine + 3,4-Dihydroxymandelate <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4-hydroxymandelate
3-Methoxy-4-hydroxyphenylacetaldehyde + NAD+ + H2O <=> Homovanillate + NADH + H+
3-Methoxy-4-hydroxyphenylacetaldehyde + NADP+ + H2O <=> Homovanillate + NADPH + H+
3-Methoxytyramine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylacetaldehyde + Hydrogen peroxide + Ammonia
3-Methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADH + H+
3-Methoxy-4-hydroxyphenylglycolaldehyde + NADP+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADPH + H+
L-Normetanephrine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylglycolaldehyde + Ammonia + Hydrogen peroxide
L-Metanephrine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylglycolaldehyde + Hydrogen peroxide + Methylamine
2-Hydroxyhepta-2,4-dienedioate + H2O <=> 4-Hydroxy-2-oxo-heptanedioate
3-(2-Hydroxyphenyl)propanoate <=> Phenylpropanoate
Isoquercitrin + UDP-L-rhamnose <=> Rutin + UDP
Luteoforol + NADP+ <=> Eriodictyol + NADPH + H+
5-Hydroxyindoleacetaldehyde + NAD+ + H2O <=> 5-Hydroxyindoleacetate + H+ + NADH
5-Hydroxyindoleacetaldehyde + Oxygen + H2O <=> 5-Hydroxyindoleacetate + Hydrogen peroxide
S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate
5-Hydroxyindoleacetate <=> 5-Hydroxyindoleacetylglycine
3-Hydroxykynurenamine + Oxygen <=> 4,8-Dihydroxyquinoline + Ammonia + Hydrogen peroxide
5-Hydroxykynurenamine + H2O + Oxygen <=> 4,6-Dihydroxyquinoline + Ammonia + Hydrogen peroxide + H2O
5-Hydroxykynurenamine + CO2 <=> 5-Hydroxykynurenine
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate + NADPH + H+ <=> 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate + NADP+
5-Hydroxy-N-formylkynurenine + H2O <=> 5-Hydroxykynurenine + Formate
5-Hydroxykynurenine + 2-Oxo acid <=> 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate + Amino acid
4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate <=> 6-Hydroxykynurenate + H2O
Quinoline-3,4-diol + Oxygen <=> Formylanthranilate + CO
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + NAD+ + H2O <=> 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate + NADH + H+
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + NADP+ + H2O <=> 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate + NADPH + H+
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + CO2 <=> 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate
3-Hydroxypropionyl-CoA + NADP+ <=> 3-Oxopropionyl-CoA + NADPH + H+
CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate
CMP-2-aminoethylphosphonate + N-Acylsphingosine <=> Ceramide 2-aminoethylphosphonate + CMP
CMP-N-trimethyl-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate
Diacylglyceryl-2-aminoethylphosphonate <=> Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate
N-Monomethyl-2-aminoethylphosphonate <=> N-Dimethyl-2-aminoethylphosphonate
ATP + Adenylylselenate <=> ADP + 3'-Phosphoadenylylselenate
ATP + Selenate <=> Diphosphate + Adenylylselenate
L-Selenocystathionine + H2O <=> L-Selenocysteine + Ammonia + 2-Oxobutanoate
L-Selenocysteine + S-Adenosyl-L-methionine <=> Se-Methyl-L-selenocysteine + S-Adenosyl-L-homocysteine
2 L-Selenocysteine <=> Selenocystine
L-Selenocysteine <=> Selenocysteine seleninic acid
L-Selenocysteine <=> Se-Propenylselenocysteine Se-oxide
(5-L-Glutamyl)-peptide + Se-Methyl-L-selenocysteine <=> Peptide + gamma-Glutamyl-Se-methylselenocysteine
3'-Phosphoadenylylselenate + NADPH <=> Adenosine 3',5'-bisphosphate + Selenite + NADP+ + H+
L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate
L-Serine + Selenohomocysteine <=> L-Selenocystathionine + H2O
2 Selenohomocysteine <=> Selenohomocystine
O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate
O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate
UDP-glucose + Cyanohydrin <=> Cyanoglycoside + UDP
Cyanoglycoside + H2O <=> Cyanohydrin + D-Glucose
Acetyl-CoA + S-Substituted L-cysteine <=> CoA + S-Substituted N-acetyl-L-cysteine
R-S-Cysteinylglycine + H2O <=> S-Substituted L-cysteine + Glycine
Butyryl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexanoyl-[acp] + CO2 + Acyl-carrier protein
(3R)-3-Hydroxyhexanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexanoyl-[acp] + NADPH + H+
(3R)-3-Hydroxyhexanoyl-[acyl-carrier protein] <=> trans-Hex-2-enoyl-[acp] + H2O
Hexanoyl-[acp] + NAD+ <=> trans-Hex-2-enoyl-[acp] + NADH + H+
Hexanoyl-[acp] + NADP+ <=> trans-Hex-2-enoyl-[acp] + NADPH + H+
Hexanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxooctanoyl-[acp] + CO2 + Acyl-carrier protein
Octanoyl-[acp] + NAD+ <=> trans-Oct-2-enoyl-[acp] + NADH + H+
Octanoyl-[acp] + NADP+ <=> trans-Oct-2-enoyl-[acp] + NADPH + H+
Octanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxodecanoyl-[acp] + CO2 + Acyl-carrier protein
Decanoyl-[acp] + NAD+ <=> trans-Dec-2-enoyl-[acp] + NADH + H+
Decanoyl-[acp] + NADP+ <=> trans-Dec-2-enoyl-[acp] + NADPH + H+
Decanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxododecanoyl-[acp] + CO2 + Acyl-carrier protein
(3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
(3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] <=> trans-Dodec-2-enoyl-[acp] + H2O
Tetradecanoyl-[acp] + NAD+ <=> trans-Tetradec-2-enoyl-[acp] + NADH + H+
Tetradecanoyl-[acp] + NADP+ <=> trans-Tetradec-2-enoyl-[acp] + NADPH + H+
Tetradecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexadecanoyl-[acp] + CO2 + Acyl-carrier protein
Hexadecanoyl-[acp] + NAD+ <=> trans-Hexadec-2-enoyl-[acp] + NADH + H+
Hexadecanoyl-[acp] + NADP+ <=> trans-Hexadec-2-enoyl-[acp] + NADPH + H+
Uroporphyrinogen I <=> Coproporphyrinogen I + 4 CO2
Cobyrinate + 1-Aminopropan-2-ol + 6 Ammonia <=> Cobinamide + 7 H2O
(3Z)-Phycocyanobilin <=> (3Z)-Phycoerythrobilin
2-Hexaprenylphenol + Oxygen + NADPH <=> 2-Hexaprenyl-6-hydroxyphenol + NADP+ + H2O
2-Hexaprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Hexaprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine
2-Polyprenylphenol + CO2 <=> 4-Hydroxy-3-polyprenylbenzoate
3-Octaprenyl-4-hydroxybenzoate <=> 2-Octaprenylphenol + CO2
2-Octaprenylphenol + Oxygen + NADPH + H+ <=> 2-Octaprenyl-6-hydroxyphenol + NADP+ + H2O
2-Octaprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Octaprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine
Demethylphylloquinol + S-Adenosyl-L-methionine <=> Phylloquinol + S-Adenosyl-L-homocysteine
Methylimidazole acetaldehyde + NAD+ + H2O <=> Methylimidazoleacetic acid + NADH + H+
cis-beta-D-Glucosyl-2-hydroxycinnamate + H2O <=> cis-2-Hydroxycinnamate + D-Glucose
cis-2-Hydroxycinnamate <=> Coumarin + H2O
all-trans-Polyprenyl diphosphate + 4-Hydroxybenzoate <=> 4-Hydroxy-3-polyprenylbenzoate + Diphosphate
2-Hydroxyphenylacetate <=> 2,6-Dihydroxyphenylacetate
GDP-mannose + beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol <=> GDP + alpha-D-Mannosyl-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol
S-Adenosyl-L-methionine + Kaempferol <=> S-Adenosyl-L-homocysteine + 3-Methoxyapigenin
Cyanidin + Succinate + CO2 + 2 H2O <=> Leucocyanidin + 2-Oxoglutarate + Oxygen + H+
Delphinidin + Succinate + CO2 + 2 H2O <=> Leucodelphinidin + 2-Oxoglutarate + Oxygen + H+
Leucodelphinidin + NADP+ <=> Dihydromyricetin + NADPH + H+
Pentahydroxyflavanone + 2-Oxoglutarate + Oxygen <=> Dihydromyricetin + Succinate + CO2
Bathorhodopsin <=> Lumirhodopsin
all-trans-Dehydroretinal <=> 11-cis-Dehydroretinal
all-trans-Dehydroretinal <=> Porphyropsin
11-cis-Dehydroretinal <=> Porphyropsin
Formamidopyrimidine nucleoside triphosphate + H2O <=> 2,5-Diaminopyrimidine nucleoside triphosphate + Formate
2,5-Diaminopyrimidine nucleoside triphosphate <=> 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine
N-Succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O <=> N-Succinyl-L-glutamate + NADH + H+
N4-Acetylaminobutanal + NAD+ + H2O <=> 4-Acetamidobutanoate + NADH + H+
L-erythro-4-Hydroxyglutamate + NADH + H+ <=> L-4-Hydroxyglutamate semialdehyde + NAD+ + H2O
L-erythro-4-Hydroxyglutamate + 2-Oxoglutarate <=> (4R)-4-Hydroxy-2-oxoglutarate + L-Glutamate
D-Aspartate + (4R)-4-Hydroxy-2-oxoglutarate <=> Oxaloacetate + L-erythro-4-Hydroxyglutamate
Leukotriene D4 + H2O <=> Leukotriene E4 + Glycine
Prostaglandin A2 <=> Prostaglandin C2
Prostaglandin B2 <=> Prostaglandin C2
Prostaglandin J2 <=> Delta-12-Prostaglandin J2
trans-Cinnamoyl beta-D-glucoside + Propane-1-ol <=> Propyl cinnamate + D-Glucose
2-Propylmalate + CoA <=> 2-Oxopentanoic acid + Acetyl-CoA + H2O
(S)-3-Hydroxyisobutyryl-CoA + H2O <=> CoA + (S)-3-Hydroxyisobutyrate
(S)-3-Hydroxyisobutyrate + NAD+ <=> (S)-Methylmalonate semialdehyde + NADH + H+
(R)-2,3-Dihydroxy-3-methylpentanoate + NADP+ <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate + NADPH + H+
(S)-2-Aceto-2-hydroxybutanoate <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate
(R)-2,3-Dihydroxy-3-methylpentanoate <=> (S)-3-Methyl-2-oxopentanoic acid + H2O
(S)-2-Acetolactate <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid
Thiosulfate + Dithioerythritol + H+ <=> Sulfite + Hydrogen sulfide + 4,5-cis-Dihydroxy-1,2-dithiacyclohexane
Tetradecanoyl-[acp] + Lauroyl-KDO2-lipid IV(A) <=> KDO2-lipid A + Acyl-carrier protein
L-erythro-3-Methylmalyl-CoA <=> 2-Methylfumaryl-CoA + H2O
Parapyruvate + Ammonia <=> 4-Hydroxy-4-methylglutamate + H2O
Parapyruvate <=> 4-Methylene-2-oxoglutarate + H2O
4-Methylene-2-oxoglutarate + Ammonia <=> 4-Methyl-L-glutamate + H2O
Trigalactosyl-diacylglycerol + UDP <=> Digalactosyl-diacylglycerol + UDP-alpha-D-galactose
Phosphatidylglycerol + Diglucosyldiacylglycerol <=> 1,2-Diacyl-sn-glycerol + Glycerophosphoglycoglycerolipid
4-Hydroxyphenylethanol + UDP-glucose <=> Salidroside + UDP
Isopyridoxal + NAD+ <=> 5-Pyridoxolactone + NADH + H+
O-Phospho-4-hydroxy-L-threonine + 2-Oxoglutarate <=> 2-Oxo-3-hydroxy-4-phosphobutanoate + L-Glutamate
O-Phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate
4-Hydroxy-L-threonine <=> 3-Aminopropane-1,2-diol + CO2
Dimethylallyltryptophan <=> Elymoclavine
Iridodial <=> Iridotrial
Iridotrial <=> 7-Deoxyloganetin
ent-Copalyl diphosphate <=> ent-Kaurene + Diphosphate
Gibberellin A53 + 2-Oxoglutarate + Oxygen <=> Gibberellin A44 diacid + Succinate + CO2
6-Hydroxyhexan-6-olide <=> Adipate semialdehyde
Adipate semialdehyde + NADP+ + H2O <=> Adipate + NADPH + H+
Adipate semialdehyde <=> Cyclohexane-1,2-dione + H2O
3'-Phosphoadenylyl sulfate + Digalactosylceramide <=> Adenosine 3',5'-bisphosphate + Digalactosylceramide sulfate
Gal-alpha1->3(Fuc-alpha1->2)Gal-beta1->3GlcNAc-beta1->3LacCer + UDP <=> Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + UDP-alpha-D-galactose
Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + UDP-N-acetyl-D-galactosamine <=> Type A glycolipid + UDP
UDP-N-acetyl-D-galactosamine + GD3 <=> UDP + GD2
UDP-alpha-D-galactose + GD2 <=> UDP + GD1b
UDP-alpha-D-galactose + GA2 <=> UDP + GA1
GA1 + H2O <=> GA2 + D-Galactose
Poly-beta-hydroxybutyrate + H2O <=> Poly[(R)-3-hydroxybutanoate]x + (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate
3-Butyn-1-al + NAD+ + H2O <=> 3-Butynoate + NADH + H+
3-Butyn-1-al + PQQ + H2O <=> 3-Butynoate + PQQH2
3-Butyn-1-al + PQQH2 <=> 3-Butyn-1-ol + PQQ
2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine + 2 S-Adenosyl-L-methionine <=> 6-(3'-Triphosphoryl-1'-methylglyceryl)-7-methyl-7,8-dihydrobiopterin + 2 S-Adenosyl-L-homocysteine + H2O
S-Adenosyl-L-methionine + (S)-Norcoclaurine <=> S-Adenosyl-L-homocysteine + (S)-Coclaurine
Codeine + NADP+ <=> Codeinone + NADPH + H+
Codeinone <=> Neopinone
Thebaine + 2-Oxoglutarate + Oxygen <=> Neopinone + Formaldehyde + Succinate + CO2
Thebaine + 2-Oxoglutarate + Oxygen <=> Oripavine + Formaldehyde + Succinate + CO2
Anabasine + CO2 <=> Piperideine + Nicotinate
Piperideine + Acetoacetyl-CoA + H2O <=> Pelletierine + CoA + CO2
Piperideine + Pelletierine <=> L-(+)-Anaferine
Pelletierine <=> N-Methylpelletierine
Protein N(pi)-phospho-L-histidine + Arbutin <=> Protein histidine + Arbutin 6-phosphate
Arbutin 6-phosphate + H2O <=> Hydroquinone + beta-D-Glucose 6-phosphate
Salicin 6-phosphate + H2O <=> Salicyl alcohol + beta-D-Glucose 6-phosphate
2',3'-Cyclic GMP + H2O <=> Guanosine 3'-phosphate
Salicylaldehyde + Pyruvate <=> trans-o-Hydroxybenzylidenepyruvate + H2O
trans-o-Hydroxybenzylidenepyruvate <=> 2-Hydroxychromene-2-carboxylate
2-Hydroxy-2,4-pentadienoate + Acetate <=> 2-Hydroxy-6-keto-2,4-heptadienoate + H2O
D-Glucose + Levan <=> Sucrose + Levan
Celloheptaose + H2O <=> Cellohexaose + D-Glucose
Cellohexaose + H2O <=> Cellopentaose + D-Glucose
Gla protein + Vitamin K1 epoxide + H2O <=> Gla protein precursor + Phylloquinol + CO2 + Oxygen
Biotinyl-5'-AMP + Apo-[carboxylase] <=> AMP + Holo-[carboxylase]
Dodecanoyl-[acyl-carrier protein] + KDO2-lipid IVA <=> Lauroyl-KDO2-lipid IV(A) + Acyl-carrier protein
Terephthalate + Oxygen + NADH + H+ <=> (3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+
2 S-Adenosyl-L-methionine + Precorrin 6Y <=> 2 S-Adenosyl-L-homocysteine + Precorrin 8X + CO2
Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+
6-Chlorobenzene-1,2,4-triol + Oxygen <=> 2-Chloromaleylacetate
4-Hydroxyquinoline + Oxygen + NADH + H+ <=> Quinoline-3,4-diol + NAD+ + H2O
2-Methylquinoline-3,4-diol + Oxygen <=> N-Acetylanthranilate + CO
2-Aminobenzenesulfonate + Oxygen + NADH + H+ <=> 3-Sulfocatechol + Ammonia + NAD+
Quinolin-2-ol + Oxygen + NADH + H+ <=> 2,5,6-Trihydroxy-5,6-dihydroquinoline + NAD+
Quinolin-2-ol + Oxygen + NADH + H+ <=> Quinolin-2,8-diol + NAD+ + H2O
S-Adenosyl-L-methionine + (R,S)-Norcoclaurine <=> S-Adenosyl-L-homocysteine + (R,S)-Coclaurine
p-Coumaroyl-CoA + Anthocyanidin-3,5-diglucoside <=> CoA + Anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside
UDP-glucose + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol <=> UDP + alpha-Kojibiosyldiacylglycerol
1-Carboxyvinyl carboxyphosphonate <=> 3-(Hydrohydroxyphosphoryl)pyruvate + CO2
Lacto-N-tetraose + H2O <=> Lacto-N-biose + Lactose
Phthalylamide + H2O <=> Phthalate + Amine
N-Acetyl-D-galactosamine 6-phosphate + H2O <=> D-Galactosamine 6-phosphate + Acetate
Methylenediurea + 2 H2O <=> N-(Hydroxymethyl)urea + CO2 + 2 Ammonia
Methylenediurea + H2O <=> N-(Carboxyaminomethyl)urea + Ammonia
N-(Carboxyaminomethyl)urea <=> N-(Aminomethyl)urea + CO2
N-(Aminomethyl)urea + H2O <=> N-(Hydroxymethyl)urea + Ammonia
2-Aryl-2-methylmalonate <=> 2-Arylpropionate + CO2
16alpha-Hydroxypregnenolone <=> 16,17-Didehydropregnenolone + H2O
omega-Agatoxin IVC <=> omega-Agatoxin IVB
ADP-D-glycero-beta-D-manno-heptose <=> ADP-L-glycero-beta-D-manno-heptose
Precorrin 8X <=> Hydrogenobyrinate
3 S-Adenosyl-L-methionine + [Ribulose-1,5-bisphosphate carboxylase]-L-lysine + H+ <=> 3 S-Adenosyl-L-homocysteine + [Ribulose-1,5-bisphosphate carboxylase]-N6,N6,N6-trimethyl-L-lysine
S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4
S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5
n UDP-D-galacturonate <=> n UDP + Pectin
Amylose + n D-Glucose <=> n Maltose
n-1 ATP + (6R)-10-Formyltetrahydropteroyldiglutamate + n-1 L-Glutamate <=> n-1 ADP + n-1 Orthophosphate + 10-Formyltetrahydrofolylpolyglutamate
Protein N(pi)-phospho-L-histidine + N-Acetyl-D-glucosamine <=> Protein histidine + N-Acetyl-D-glucosamine 6-phosphate
Phytic acid + ADP <=> 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate + ATP
Leukotriene E4 + L-Glutamate <=> Leukotriene F4 + H2O
Diacylglycerol + H2O <=> 1-Acylglycerol + Carboxylate
S-Adenosyl-L-methionine + (S)-Norreticuline <=> S-Adenosyl-L-homocysteine + (S)-Reticuline
S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-Norreticuline
S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-Nororientaline
S-Adenosyl-L-methionine + (S)-Norlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-6-O-Methylnorlaudanosoline
S-Adenosyl-L-methionine + (R)-Norreticuline <=> S-Adenosyl-L-homocysteine + (R)-Reticuline
Cob(I)yrinate a,c diamide + ATP <=> Adenosyl cobyrinate a,c diamide + Triphosphate
Adenosyl cobinamide + ATP <=> Adenosyl cobinamide phosphate + ADP
Adenosyl cobinamide phosphate + GTP <=> Adenosine-GDP-cobinamide + Diphosphate
Adenosyl cobyrinate hexaamide + (R)-1-Aminopropan-2-ol <=> Adenosyl cobinamide + H2O
Hydrogenobyrinate a,c diamide + Cobalt ion + ATP + H2O <=> Cob(II)yrinate a,c diamide + Orthophosphate + ADP + H+
Deacetylcephalosporin C + H2O + 2 Succinate + 2 CO2 <=> Penicillin N + 2 2-Oxoglutarate + 2 Oxygen
Deacetylcephalosporin C + Succinate + CO2 <=> Deacetoxycephalosporin C + 2-Oxoglutarate + Oxygen
Deacetylcephalosporin C + Carbamoyl phosphate <=> O-Carbamoyl-deacetylcephalosporin C + Orthophosphate
6-Hydroxyhexanoic acid + NADP+ <=> Adipate semialdehyde + NADPH + H+
p-Cumic alcohol + NAD+ <=> 4-Isopropylbenzaldehyde + NADH + H+
trans-3-Chloro-2-propene-1-ol + NAD+ <=> trans-3-Chloroallyl aldehyde + NADH + H+
cis-3-Chloro-2-propene-1-ol + NAD+ <=> cis-3-Chloroallyl aldehyde + NADH + H+
4-Isopropylbenzaldehyde + NAD+ + H2O <=> p-Cumate + NADH + H+
cis,cis-4-Hydroxymuconic semialdehyde + NAD+ + H2O <=> 2-Maleylacetate + NADH + H+
trans-3-Chloroallyl aldehyde + H2O <=> trans-3-Chloroacrylic acid + 2 H+
cis-3-Chloroallyl aldehyde + H2O <=> cis-3-Chloroacrylic acid + 2 H+
cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NAD+ <=> Biphenyl-2,3-diol + NADH + H+
cis-2,3-Dihydroxy-2,3-dihydro-p-cumate + NAD+ <=> 2,3-Dihydroxy-p-cumate + NADH + H+
cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NAD+ <=> 2,3-Dihydroxy-4'-chlorobiphenyl + NADH + H+
2,5-Dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ <=> 2,5-Dichlorohydroquinone + NADH + H+
p-Benzoquinone + NADPH + H+ <=> Hydroquinone + NADP+
2,3-Dihydroxy-4'-chlorobiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate
Hydroquinone + Oxygen <=> cis,cis-4-Hydroxymuconic semialdehyde
p-Cumate + Oxygen + NADH + H+ <=> cis-2,3-Dihydroxy-2,3-dihydro-p-cumate + NAD+
2,3-Dihydroxy-p-cumate + Oxygen <=> 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate
Resorcinol + Oxygen + NADPH + H+ <=> Benzene-1,2,4-triol + NADP+ + H2O
1,2,3-Trihydroxybenzene + NADP+ + H2O <=> Resorcinol + Oxygen + NADPH + H+
2,2-Bis(4'-chlorophenyl)ethanol + H2O <=> Bis(4'-chlorophenyl)acetate + 4 H+
4-Chlorobenzoate <=> 4-Chlorobenzaldehyde + H2O
1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene + Oxygen <=> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate
2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + Oxygen <=> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate
p-Benzoquinone + Nitrite + NADP+ + H2O <=> 4-Nitrophenol + Oxygen + NADPH + H+
4-Chlorobiphenyl + Oxygen + NADH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NAD+
4-Chlorobiphenyl + Oxygen + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NADP+
Biphenyl + Oxygen + NADH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NAD+
Biphenyl + Oxygen + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NADP+
4-Nitrocatechol + Oxygen + 3 H+ <=> Benzene-1,2,4-triol + Nitrite + H2O
Hydrochloric acid + Hydroquinone + Glutathione disulfide <=> Chlorohydroquinone + 2 Glutathione
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + H+ <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Cl-
2,5-Dichlorohydroquinone + 2 Glutathione <=> Chlorohydroquinone + Glutathione disulfide + Hydrochloric acid
4-Sulfobenzyl alcohol + NAD+ <=> 4-Sulfobenzaldehyde + NADH + H+
4-Sulfobenzaldehyde + NAD+ + H2O <=> 4-Sulfobenzoate + NADH + H+
Vanillate + NAD+ + H2O <=> 4-Hydroxy-3-methoxy-benzaldehyde + Oxygen + NADH + H+
Vanillate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde
cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ <=> 4,5-Dihydroxyphthalate + NADH + H+
4-Chlorobenzoyl-CoA + Hydrochloric acid + NADP+ <=> 2,4-Dichlorobenzoyl-CoA + NADPH + H+
4-Aminobenzenesulfonate + 4-Aminobenzoate <=> 4-Carboxy-4'-sulfoazobenzene + 4 H+
4-Sulfocatechol + Oxygen <=> 3-Sulfomuconate
4-Aminobenzenesulfonate + Oxygen + 2 H+ <=> 4-Sulfocatechol + Ammonia
3,4-Dihydroxybenzoate + Ammonia <=> 4-Aminobenzoate + Oxygen + 2 H+
Toluene-4-sulfonate + Oxygen + NADH + H+ <=> 4-Sulfobenzyl alcohol + NAD+ + H2O
4-Methylbenzyl alcohol + NAD+ <=> p-Tolualdehyde + NADH + H+
6-Hydroxyhexanoic acid + NAD+ <=> Adipate semialdehyde + NADH + H+
1,2-Dichloroethane + H2O <=> 2-Chloroethanol + Hydrochloric acid
Chloroacetaldehyde + NAD+ + H2O <=> Chloroacetic acid + NADH + H+
Chloroacetic acid + H2O <=> Glycolate + Hydrochloric acid
p-Tolualdehyde + NADP+ + H2O <=> Toluate + NADPH + H+
Toluate + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD+
Toluate + Oxygen + NADPH + H+ <=> cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+
cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD+ <=> 4-Methylcatechol + CO2 + NADH + H+
cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ <=> 4-Methylcatechol + CO2 + NADPH + H+
Toluene-4-sulfonate + Oxygen + NADH + H+ <=> 4-Methylcatechol + Sulfite + NAD+
4-Methylcatechol + Oxygen <=> 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + H2O <=> Formate + (4E)-2-Oxohexenoic acid
(4E)-2-Oxohexenoic acid + H2O <=> 4-Hydroxy-2-oxohexanoic acid
Propanal + Pyruvate <=> 4-Hydroxy-2-oxohexanoic acid
4-Methylcatechol + Oxygen <=> 3-Methyl-cis,cis-hexadienedioate
4-Methylmuconolactone <=> 3-Methyl-cis,cis-hexadienedioate
Penicillin N + 2-Oxoglutarate + Oxygen <=> Deacetoxycephalosporin C + Succinate + CO2 + H2O
O-Carbamoyl-deacetylcephalosporin C + 2-Oxoglutarate + Oxygen <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + Succinate + CO2
Cephamycin C + S-Adenosyl-L-homocysteine <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + S-Adenosyl-L-methionine
Nucleoside + Deoxynucleoside 5'-phosphate <=> Deoxynucleoside + Nucleoside 3'-phosphate
3-Hydroxypimeloyl-CoA + NAD+ <=> 3-Oxopimeloyl-CoA + NADH + H+
Formaldehyde + Mycothiol + NAD+ <=> S-Formylmycothiol + NADH + H+
Dihydrophloroglucinol + NADP+ <=> Phloroglucinol + NADPH + H+
1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ <=> 2,3-Dihydroxytoluene + CO2 + NADH + H+
cis-1,2-Dihydroxy-1,2-dihydrodibenzothiophene + NAD+ <=> 1,2-Dihydroxydibenzothiophene + NADH + H+
Pimeloyl-CoA + NAD+ <=> 6-Carboxyhex-2-enoyl-CoA + NADH + H+
5,6-Dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+ <=> 5,6-Dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H+
cis-1,2-Dihydro-3-ethylcatechol + NAD+ <=> 3-Ethylcatechol + NADH + H+
1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ <=> 2,3-Dihydroxytoluene + NADH + CO2 + H+
(1S,3R,4S)-3,4-Dihydroxycyclohexane-1-carboxylate + NAD+ <=> (1S,4S)-4-Hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H+
L-Tryptophan + Oxygen <=> alpha,beta-Didehydrotryptophan + Hydrogen peroxide
Ferrocytochrome c + Fe3+ <=> Ferricytochrome c + Fe2+
Taurine + 2-Oxoglutarate + Oxygen <=> Sulfite + Aminoacetaldehyde + Succinate + CO2
S-Adenosyl-L-methionine + 3-O-Methylquercetin <=> S-Adenosyl-L-homocysteine + 3,7-Di-O-methylquercetin
UDP-glucose + cis-p-Coumarate <=> 4'-O-beta-D-Glucosyl-cis-p-coumarate + UDP
UDP-glucose + Limonin <=> Glucosyl-limonin + UDP
Lacto-N-biose + Orthophosphate <=> alpha-D-Galactose 1-phosphate + N-Acetyl-D-glucosamine
n UDP-N-acetyl-alpha-D-glucosamine + n UDP-glucuronate <=> Hyaluronate + 2n UDP
ADP-glucose + sn-Glycerol 3-phosphate <=> 2-(alpha-D-Glucosyl)-sn-glycerol 3-phosphate + ADP
[eIF5A-precursor]-lysine + Spermidine <=> [eIF5A-precursor]-deoxyhypusine + 1,3-Diaminopropane
4,8,12-Trimethyltridecanoyl-CoA + Propanoyl-CoA <=> 3-Oxopristanoyl-CoA + CoA
Acetyl-CoA + alpha-D-Glucosamine 1-phosphate <=> CoA + N-Acetyl-alpha-D-glucosamine 1-phosphate
Phospholipid + 1,2-Diacyl-sn-glycerol <=> Lysophospholipid + Triacylglycerol
N-Methylputrescine + Oxygen + H2O <=> 4-Methylaminobutanal + Hydrogen peroxide + Ammonia
4-Methylaminobutanal <=> 1-Methylpyrrolinium + H2O
4-Hydroxybutanoic acid + Acetyl-CoA <=> 4-Hydroxybutyryl-CoA + Acetate
4-Hydroxybutyryl-CoA <=> Vinylacetyl-CoA + H2O
D-Ribulose 5-phosphate + Formaldehyde <=> D-arabino-Hex-3-ulose 6-phosphate
D-arabino-Hex-3-ulose 6-phosphate <=> D-Fructose 6-phosphate
Lycopene <=> gamma-Carotene
4-Chloroacetophenone <=> 4-Chlorobenzaldehyde + CO2
3-Methylbenzyl alcohol + NAD+ <=> 3-Methylbenzaldehyde + NADH + H+
2-Methylbenzyl alcohol + NAD+ <=> 2-Methylbenzaldehyde + NADH + H+
Fluoren-9-ol + NAD+ <=> Fluoren-9-one + NADH + H+
Fluoren-9-ol + NADP+ <=> Fluoren-9-one + NADPH + H+
Ethylene oxide + CoA + NAD+ <=> Acetyl-CoA + NADH + H+
(S)-1-Phenylethanol + NAD+ <=> Acetophenone + NADH + H+
2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + NAD+ + H2O <=> 2-Hydroxy-5-methyl-cis,cis-muconate + NADH + H+
Styrene-cis-2,3-dihydrodiol + NAD+ <=> 3-Vinylcatechol + NADH + H+
2-Chloromaleylacetate + NADH <=> 2-Maleylacetate + NAD+ + Cl-
epsilon-Caprolactam + H2O <=> 6-Aminohexanoate
Guanidinoproclavaminic acid + H2O <=> Proclavaminic acid + Urea
Acrylonitrile + 2 H2O <=> Acrylic acid + Ammonia
2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate + H2O <=> 4-Chlorobenzoate + 2-Hydroxy-2,4-pentadienoate
2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate + H2O <=> Salicylate + 2-Hydroxy-2,4-pentadienoate
2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate + H2O <=> 2-Hydroxymuconate + Catechol
2-Hydroxy-6-oxoocta-2,4,7-trienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Acrylic acid
6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate + H2O <=> 2-(4'-Chlorophenyl)-3,3-dichloropropenoate + 2-Hydroxy-3-chloropenta-2,4-dienoate
2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O <=> 2-Methylpropanoate + 2-Hydroxy-2,4-pentadienoate
2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Anthranilate
2-Hydroxy-6-oxo-octa-2,4-dienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Propanoate
trans-1,3-Dichloropropene + H2O <=> trans-3-Chloro-2-propene-1-ol + Hydrochloric acid
cis-1,3-Dichloropropene + H2O <=> cis-3-Chloro-2-propene-1-ol + Hydrochloric acid
1,3,4,6-Tetrachloro-1,4-cyclohexadiene + H2O <=> 2,4,5-Trichloro-2,5-cyclohexadiene-1-ol + Hydrochloric acid
2,4,5-Trichloro-2,5-cyclohexadiene-1-ol + H2O <=> 2,5-Dichloro-2,5-cyclohexadiene-1,4-diol + Hydrochloric acid
trans-3-Chloroacrylic acid + H2O <=> Hydrochloric acid + 3-Oxopropanoate
cis-3-Chloroacrylic acid + H2O <=> Hydrochloric acid + 3-Oxopropanoate
Methylmalonyl-CoA <=> Propanoyl-CoA + CO2
2-Oxo-5-methyl-cis-muconate <=> 2-Hydroxy-cis-hex-2,4-dienoate + CO2
4-Hydroxyphthalate <=> 3-Hydroxybenzoate + CO2
Bis(4'-chlorophenyl)methane + CO2 <=> Bis(4'-chlorophenyl)acetate
2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate <=> 2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate + CO2
2-Deoxy-5-keto-D-gluconic acid 6-phosphate <=> 3-Oxopropanoate + Glycerone phosphate
Acrylamide <=> Acrylonitrile + H2O
Acetaldehyde <=> Acetylene + H2O
Ethanolamine + Acetaldehyde <=> Diethanolamine
Triethanolamine <=> Diethanolamine + Acetaldehyde
2-Aminophenol <=> Hydroxylaminobenzene
TDE <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Hydrochloric acid
1-Chloro-2,2-bis(4'-chlorophenyl)ethane <=> unsym-Bis(4'-chlorophenyl)ethylene + Hydrochloric acid
Lindane <=> gamma-Pentachlorocyclohexene + Hydrochloric acid
gamma-Pentachlorocyclohexene <=> 1,3,4,6-Tetrachloro-1,4-cyclohexadiene + Hydrochloric acid
5-Chloro-1,2,4-trihydroxybenzene <=> 2-Hydroxy-1,4-benzoquinone + Hydrochloric acid
2-Hydroxy-5-methyl-cis,cis-muconate <=> 2-Oxo-5-methyl-cis-muconate
3-Chloro-cis,cis-muconate <=> Protoanemonin + Hydrochloric acid + CO2
3-Chloro-cis,cis-muconate <=> cis-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid
trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid <=> 2,5-Dichloro-cis,cis-muconate
2,4-Dichloro-cis,cis-muconate <=> trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid
3-Sulfomuconate <=> 4-Sulfolactone
cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NAD+ <=> 2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADH + H+
cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADP+ <=> 2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADPH + H+
3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3,6-Dichlorocatechol + NADH + H+
2-Hydroxy-1,4-benzoquinone + NADH + H+ <=> Benzene-1,2,4-triol + NAD+
Nitrosobenzene + NADPH + H+ <=> Hydroxylaminobenzene + NADP+
Nitrobenzene + NADPH + H+ <=> Nitrosobenzene + NADP+ + H2O
Tetrachlorohydroquinone + 2 Glutathione <=> 2,3,6-Trichlorohydroquinone + Glutathione disulfide + Hydrochloric acid
2,3,6-Trichlorohydroquinone + 2 Glutathione <=> 2,6-Dichlorohydroquinone + Glutathione disulfide + Hydrochloric acid
3-Vinylcatechol + Oxygen <=> 2-Hydroxy-6-oxoocta-2,4,7-trienoate
2-Aminophenol + Oxygen <=> 2-Aminomuconate semialdehyde
4-Chlorocatechol + Oxygen <=> 5-Chloro-2-hydroxymuconic semialdehyde
3,5-Dichlorocatechol + Oxygen <=> 2,4-Dichloro-cis,cis-muconate
2,6-Dichlorohydroquinone + Oxygen + H2O <=> 2-Chloromaleylacetate + Hydrochloric acid
3,6-Dichlorocatechol + Oxygen <=> 2,5-Dichloro-cis,cis-muconate
3,4-Dihydroxyfluorene + Oxygen <=> 2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid
2,2',3-Trihydroxybiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate
1,2-Dihydroxyfluorene + Oxygen <=> 2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid
2,2',3-Trihydroxydiphenylether + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate
Carbazole + Oxygen + NADH + H+ <=> 2'-Aminobiphenyl-2,3-diol + NAD+
2'-Aminobiphenyl-2,3-diol + Oxygen <=> 2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate
3-Ethylcatechol + Oxygen <=> 2-Hydroxy-6-oxo-octa-2,4-dienoate + H+
Styrene + Oxygen + NADH + H+ <=> Styrene-cis-2,3-dihydrodiol + NAD+
2,4,5-Trichlorophenoxyacetic acid + Oxygen + NADH + H+ <=> 2,4,5-Trichlorophenol + Glyoxylate + NAD+ + H2O
2,4-Dichlorophenoxyacetate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Glyoxylate + Succinate + CO2
4-Sulfolactone + H2O <=> HSO3- + 2-Maleylacetate + H+
Parathion + H2O <=> Diethylthiophosphoric acid + 4-Nitrophenol
Fluorene + Oxygen + NADH + H+ <=> Fluoren-9-ol + NAD+ + H2O
Fluorene + Oxygen + NADH + H+ <=> (+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene + NAD+
Ethylbenzene <=> Styrene + 2 H+
Ethylbenzene + Oxygen + NADH + H+ <=> (S)-1-Phenylethanol + NAD+ + H2O
(S)-1-Phenylethanol + Oxygen + NADH + H+ <=> Acetophenone + NAD+ + 2 H2O
2 Acetophenone + Oxygen <=> 2 2-Hydroxyacetophenone
o-Toluate + Oxygen + NADH + H+ <=> 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+
1,4-Dichlorobenzene + Oxygen + NADH + H+ <=> 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
2 Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 Dihydrocoumarin + 2 NAD+
2 Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 3-Hydroxy-1-indanone + 2 NAD+
2 Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 Dihydrocoumarin + 2 NADP+
2 Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 3-Hydroxy-1-indanone + 2 NADP+
Dibenzofuran + Oxygen + NADH + H+ <=> 2,2',3-Trihydroxybiphenyl + NAD+
Fluoren-9-one + Oxygen + 2 NADH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NAD+
Fluoren-9-one + Oxygen + 2 NADPH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NADP+
2 2-Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 3-Isochromanone + 2 NAD+
2 2-Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 3-Isochromanone + 2 NADP+
Dibenzo-p-dioxin + Oxygen + NADH + H+ <=> 2,2',3-Trihydroxydiphenylether + NAD+
Ethylbenzene + Oxygen + NADH + H+ <=> cis-1,2-Dihydro-3-ethylcatechol + NAD+
4-Chlorophenol + Oxygen + NADPH + H+ <=> 4-Chlorocatechol + NADP+ + H2O
Ethylene + Oxygen + NADH + H+ <=> Ethylene oxide + NAD+ + H2O
2,6-Dichlorohydroquinone + H2O <=> 6-Chlorobenzene-1,2,4-triol + Hydrochloric acid
2,5-Dichlorohydroquinone + FADH2 + Oxygen <=> 5-Chloro-2-hydroxy-p-benzoquinone + FAD + H2O + Cl-
2,4,5-Trichlorophenol + FADH2 + Oxygen <=> 2,5-Dichloro-p-benzoquinone + FAD + H2O + Cl-
2,6-Dichlorophenol + Oxygen + NADH + H+ <=> 2,6-Dichlorohydroquinone + NAD+ + H2O
2,4,6-Trichlorophenol + FADH2 + Oxygen <=> 2,6-Dichloro-p-benzoquinone + FAD + H2O + Cl-
2-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> Homogentisate + NAD+ + H2O
CoA + ATP + 2,4-Dichlorobenzoate <=> Diphosphate + 2,4-Dichlorobenzoyl-CoA + AMP
3-Oxo-3-phenylpropanoate + CoA + ATP <=> Diphosphate + Benzoylacetyl-CoA + AMP
2 ATP + Acetophenone + HCO3- + H2O + H+ <=> 2 ADP + 2 Orthophosphate + 3-Oxo-3-phenylpropanoate
2-Succinylbenzoate <=> Spirodilactone + H2O
2-Succinylbenzoyl-CoA <=> Spirodilactone + CoA
Tetracycline + Coenzyme F420 <=> 5a,11a-Dehydrotetracycline + Reduced coenzyme F420
4-Hydroxy-6-methylpretetramide + NADPH + Oxygen + H+ <=> 4-Keto-anhydrotetracycline + NADP+ + H2O
6-Methylpretetramide + NADPH + Oxygen + H+ <=> 4-Hydroxy-6-methylpretetramide + NADP+ + H2O
D-Glyceraldehyde 3-phosphate + L-Arginine <=> L-N2-(2-Carboxyethyl)arginine + Orthophosphate
Deoxyguanidinoproclavaminic acid + 2-Oxoglutarate + Oxygen <=> Guanidinoproclavaminic acid + Succinate + CO2
L-N2-(2-Carboxyethyl)arginine + ATP <=> Deoxyguanidinoproclavaminic acid + AMP + Diphosphate
Proclavaminic acid + Oxygen + 2-Oxoglutarate <=> Dihydroclavaminic acid + CO2 + Succinate + H2O
Dihydroclavaminic acid + Oxygen + 2-Oxoglutarate <=> Clavaminic acid + Succinate + CO2 + H2O
Clavaminic acid <=> Clavulanate-9-aldehyde
Clavulanate-9-aldehyde + NADPH + H+ <=> Clavulanic acid + NADP+
6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate <=> 4-Chlorobenzoate
Bis(4'-chlorophenyl)methane <=> 4-Chlorophenylacetate
2-(4'-Chlorophenyl)-3,3-dichloropropenoate <=> 4-Chlorophenylacetate
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + NADH + H+ + Oxygen <=> cis-3-[2,2-Dichloro-1-(4-chlorophenyl)vinyl]-6-chlorocyclohexa-3,5-diene-1,2-diol + NAD+
DDT <=> TDE + Cl-
1-Chloro-2,2-bis(4'-chlorophenyl)ethane + H2O <=> 2,2-Bis(4'-chlorophenyl)ethanol + Hydrochloric acid
2,2-Bis(4'-chlorophenyl)ethanol <=> unsym-Bis(4'-chlorophenyl)ethylene + H2O
Bis(4'-chlorophenyl)acetate <=> 4,4'-Dichlorobenzophenone
2-(4'-Chlorophenyl)-3,3-dichloropropenoate <=> 4-Chloroacetophenone
Bis(4'-chlorophenyl)acetate <=> 2,2-Bis(4'-chlorophenyl)ethanol + H2O
1,2,4-Trichlorobenzene + Hydrochloric acid <=> 1,3,4,6-Tetrachloro-1,4-cyclohexadiene
2,4,5-Trichloro-2,5-cyclohexadiene-1-ol <=> 2,5-Dichlorophenol + Hydrochloric acid
Aminoparathion + H2O <=> Diethylthiophosphoric acid + 4-Hydroxyaniline
Diethylthiophosphoric acid + H2O <=> Diethylphosphoric acid + Hydrogen sulfide
Styrene + FADH2 + Oxygen <=> (S)-2-Phenyloxirane + FAD + H2O
DDT + Oxygen <=> cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane
4-Chlorophenoxyacetate + 2-Oxoglutarate + Oxygen <=> 4-Chlorophenol + Glyoxylate + Succinate + CO2
Ethylbenzene + H2O <=> 1-Phenylethanol + 2 H+
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Cl-
Vinyl chloride + 2 H+ <=> Ethylene + Hydrochloric acid
Tetrachloroethene + 2 H+ <=> Trichloroethene + Hydrochloric acid
Trichloroethene + 2 H+ <=> trans-1,2-Dichloroethene + Hydrochloric acid
Trichloroethene + 2 H+ <=> cis-1,2-Dichloroethene + Hydrochloric acid
trans-1,2-Dichloroethene + 2 H+ <=> Vinyl chloride + Hydrochloric acid
cis-1,2-Dichloroethene + 2 H+ <=> Vinyl chloride + Hydrochloric acid
5-Chloro-2-hydroxymuconic semialdehyde + H+ <=> 2-Hydroxymuconate semialdehyde + Cl-
Benzoylacetyl-CoA + CoA <=> Benzoyl-CoA + Acetyl-CoA
6-Aminohexanoate + 2-Oxoglutarate <=> Adipate semialdehyde + L-Glutamate
Lactoyl-CoA + Acetate <=> (S)-Lactate + Acetyl-CoA
Acetyl-CoA + Acrylic acid <=> Acetate + Propenoyl-CoA
Protoanemonin + H2O <=> cis-Acetylacrylate
cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + H2O <=> 2-Chloromaleylacetate
Streptomycin 6-phosphate + NADH + H+ <=> Dihydrostreptomycin 6-phosphate + NAD+
dTDP-L-rhamnose <=> dTDP-L-dihydrostreptose
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + H2O
Erythromycin + Oxygen <=> Erythromycin E + H2O
S-Adenosyl-L-methionine + Erythromycin C <=> S-Adenosyl-L-homocysteine + Erythromycin
Erythromycin D + NADPH + H+ + Oxygen <=> Erythromycin C + NADP+ + H2O
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + NADPH + H+ <=> dTDP-4-oxo-2,6-dideoxy-D-glucose + NADP+
Erythronolide B + dTDP-L-mycarose <=> 3-O-alpha-Mycarosylerythronolide B + dTDP
dTDP-D-desosamine + 3-O-alpha-Mycarosylerythronolide B <=> Erythromycin D + dTDP
S-Adenosyl-L-methionine + Erythromycin D <=> S-Adenosyl-L-homocysteine + Erythromycin B
beta-1,2,3,4,5,6-Hexachlorocyclohexane <=> delta-3,4,5,6-Tetrachlorocyclohexene + 2 Cl-
delta-3,4,5,6-Tetrachlorocyclohexene <=> 5,6-Dichloro-1,3-cyclohexadiene + 2 Cl-
5,6-Dichloro-1,3-cyclohexadiene <=> Chlorobenzene + Cl- + H+
5,6-Dichloro-1,3-cyclohexadiene <=> Benzene + 2 Cl-
2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid + H2O <=> 2-Formyl-1-indanone + Pyruvate
CO2 <=> 3-Isochromanone
2 Indanone + 2 CO2 <=> 2 2-Formyl-1-indanone + Oxygen
Fluorene + Oxygen + 2 H+ <=> 3,4-Dihydroxyfluorene
Fluorene + Oxygen + 2 H+ <=> 1,2-Dihydroxyfluorene
3,4-Dihydroxy-3,4-dihydro-9-fluorenone <=> 4-Hydroxy-9-fluorenone + H2O
2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid + H2O <=> 1-Formyl-2-indanone + Pyruvate
2-Amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 H2O <=> 1,4-Cyclohexanedione + Ammonia + CO2 + CoA
N1-Amidinostreptamine 6-phosphate + L-Arginine <=> Streptidine 6-phosphate + L-Ornithine
Paraoxon + H2O <=> Diethylphosphoric acid + 4-Nitrophenol
D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose
Acrylic acid + Ammonia <=> Acrylamide + H2O
Chorismate + Ammonia <=> 4-Amino-4-deoxychorismate + H2O
4-Amino-4-deoxychorismate <=> 4-Aminobenzoate + Pyruvate
(S)-Ureidoglycine + H2O <=> (S)-Ureidoglycolate + Ammonia
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate <=> trans,trans,cis-Geranylgeranyl diphosphate + Diphosphate
trans,trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> ditrans,polycis-Polyprenyl diphosphate + n Diphosphate
Atrazine + H2O <=> Hydroxyatrazine + Hydrochloric acid
Hydroxyatrazine + H2O <=> N-Isopropylammelide + Ethylamine
N-Isopropylammelide + H2O <=> Cyanuric acid + Isopropylamine
Biuret + H2O <=> Urea-1-carboxylate + Ammonia
2 Atrazine + Oxygen <=> 2 Deisopropylatrazine + 2 Acetone
2 Atrazine + Oxygen <=> 2 Deethylatrazine + 2 Acetaldehyde
UDP-N-acetyl-D-mannosamine + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + N-Acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
2 Deisopropylatrazine + Oxygen <=> 2 Deisopropyldeethylatrazine + 2 Acetaldehyde
2 Deethylatrazine + Oxygen <=> 2 Deisopropyldeethylatrazine + 2 Acetone
Deisopropyldeethylatrazine + H2O <=> 2-Chloro-4-hydroxy-6-amino-1,3,5-triazine + Ammonia
Galactitol + Protein N(pi)-phospho-L-histidine <=> Galactitol 1-phosphate + Protein histidine
Galactitol 1-phosphate + NAD+ <=> D-Tagatose 6-phosphate + NADH + H+
Deisopropylatrazine + H2O <=> Deisopropylhydroxyatrazine + Hydrochloric acid
N-Ethylammelide + H2O <=> Cyanuric acid + Ethylamine
Deisopropylhydroxyatrazine + H2O <=> N-Ethylammelide + Ammonia
(2S)-[(R)-Hydroxy(phenyl)methyl]succinyl-CoA + NAD+ <=> (S)-2-Benzoylsuccinyl-CoA + NADH + H+
3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
CMP-N-acetylneuraminate + beta-D-Galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ <=> 6-Oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+
2-Hydroxycyclohexane-1-carbonyl-CoA + NAD+ <=> 2-Oxocyclohexane-1-carbonyl-CoA + NADH + H+
Anthraniloyl-CoA + 2 H+ <=> Benzoyl-CoA + Ammonia
3-Oxopimeloyl-CoA + CoA <=> Glutaryl-CoA + Acetyl-CoA
(S)-2-Benzoylsuccinyl-CoA + CoA <=> Benzoyl-CoA + Succinyl-CoA
Benzylsuccinate + Succinyl-CoA <=> Benzylsuccinyl-CoA + Succinate
Benzamide + H2O <=> Benzoate + Ammonia
Benzonitrile + 2 H2O <=> Benzoate + Ammonia
2-Oxocyclohexane-1-carbonyl-CoA + H2O <=> Pimeloyl-CoA
2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA
6-Oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O <=> 3-Hydroxypimeloyl-CoA
Crotonoyl-CoA + H2O <=> 3-Hydroxybutanoyl-CoA
Benzonitrile + H2O <=> Benzamide
Cyclohexa-1,5-diene-1-carbonyl-CoA + H2O <=> 6-Hydroxycyclohex-1-ene-1-carbonyl-CoA
Toluene + Fumarate <=> Benzylsuccinate
E-Phenylitaconyl-CoA + H2O <=> (2S)-[(R)-Hydroxy(phenyl)methyl]succinyl-CoA
Cyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-Hydroxycyclohexane-1-carbonyl-CoA
6-Carboxyhex-2-enoyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2,6-Dihydroxycyclohexane-1-carbonyl-CoA
Phenolic phosphate + CO2 + H2O <=> 4-Hydroxybenzoate + Orthophosphate
D-Arabitol + NAD+ <=> D-Xylulose + NADH + H+
2-Dehydro-3-deoxy-6-phospho-D-gluconate <=> D-Glyceraldehyde 3-phosphate + Pyruvate
D-Mannonate <=> 2-Dehydro-3-deoxy-D-gluconate + H2O
Sorbitol 6-phosphate + NAD+ <=> beta-D-Fructose 6-phosphate + NADH + H+
D-Galactarate <=> 5-Dehydro-4-deoxy-D-glucarate + H2O
Cyclohexa-1,5-diene-1-carbonyl-CoA <=> Cyclohexa-2,5-diene-1-carbonyl-CoA
Cyclohexa-1,5-diene-1-carbonyl-CoA <=> Cyclohexa-1,4-diene-1-carbonyl-CoA
all-trans-Octaprenyl diphosphate + Diphosphate <=> all-trans-Heptaprenyl diphosphate + Isopentenyl diphosphate
all-trans-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + Diphosphate
all-trans-Pentaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + Diphosphate
all-trans-Octaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Octaprenyl-4-hydroxybenzoate + Diphosphate
all-trans-Hexaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Hexaprenyl-4-hydroxybenzoate + Diphosphate
Chlorophyll a + H2O <=> Chlorophyllide + Phytol
Cyclohexane-1-carboxylate + CoA + ATP <=> Cyclohexane-1-carbonyl-CoA + AMP + Diphosphate
Benzoate + NADH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
Benzoate + NADPH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NADP+
Trimethylamine + NADPH + H+ + Oxygen <=> Trimethylamine N-oxide + NADP+ + H2O
H2O + Levan(m+n) <=> Levan(m) + Levan(n)
Phenol + ATP + H2O <=> Phenolic phosphate + AMP + Orthophosphate
ATP + di-trans,poly-cis-Undecaprenol <=> ADP + di-trans,poly-cis-Undecaprenyl phosphate
di-trans,poly-cis-Undecaprenyl diphosphate + H2O <=> di-trans,poly-cis-Undecaprenyl phosphate + Orthophosphate
UDP-N-acetyl-D-galactosamine + alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + Globoside
1-Hydroxy-2-naphthoate + NADH + H+ + Oxygen <=> Naphthalene-1,2-diol + CO2 + NAD+ + H2O
2-C-Methyl-D-erythritol 4-phosphate + CTP <=> 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol + Diphosphate
4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ATP <=> 2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ADP
Formyl-L-methionyl peptide + H2O <=> Methionyl peptide + Formate
Pyruvate + D-Glyceraldehyde 3-phosphate <=> 1-Deoxy-D-xylulose 5-phosphate + CO2
2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol <=> 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate + CMP
14-Demethyllanosterol + NADP+ <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+
Ergosterol + NADP+ <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADPH + H+
2-Hydroxy-2H-benzo[h]chromene-2-carboxylate <=> cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate
2-Carboxybenzaldehyde + NAD+ + H2O <=> Phthalate + NADH + H+
ATP + D-glycero-beta-D-manno-Heptose 1-phosphate <=> Diphosphate + ADP-D-glycero-beta-D-manno-heptose
Sedoheptulose 7-phosphate <=> D-glycero-beta-D-manno-Heptose 7-phosphate
ATP + D-glycero-beta-D-manno-Heptose 7-phosphate <=> ADP + D-glycero-beta-D-manno-Heptose 1,7-bisphosphate
D-glycero-beta-D-manno-Heptose 1,7-bisphosphate + H2O <=> D-glycero-beta-D-manno-Heptose 1-phosphate + Orthophosphate
cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O <=> 1-Hydroxy-2-naphthaldehyde + Pyruvate
1-Hydroxy-2-naphthaldehyde + NAD+ + H2O <=> 1-Hydroxy-2-naphthoate + NADH + H+
Phenanthrene-3,4-diol + Oxygen <=> 2-Hydroxy-2H-benzo[h]chromene-2-carboxylate
Sulfoacetaldehyde + Orthophosphate <=> Acetyl phosphate + Sulfite
Taurine + Pyruvate <=> Sulfoacetaldehyde + L-Alanine
Phenanthrene + Oxygen + NADH + H+ <=> Phenanthrene-9,10-oxide + H2O + NAD+
Phenanthrene + Oxygen + NADH + H+ <=> Phenanthrene-1,2-oxide + H2O + NAD+
Phenanthrene + Oxygen + NADH + H+ <=> 1-Phenanthrol + H2O + NAD+
Phenanthrene-1,2-oxide <=> 1-Phenanthrol
Phenanthrene-9,10-oxide + H2O <=> trans-9(S),10(S)-Dihydrodiolphenanthrene
2,4,6/3,5-Pentahydroxycyclohexanone <=> D-2,3-Diketo 4-deoxy-epi-inositol + H2O
2-Deoxy-5-keto-D-gluconic acid + ATP <=> 2-Deoxy-5-keto-D-gluconic acid 6-phosphate + ADP
2-Methylbenzaldehyde + NADP+ + H2O <=> o-Toluate + NADPH + H+
3-Methylbenzaldehyde + NADP+ + H2O <=> m-Methylbenzoate + NADPH + H+
m-Methylbenzoate + NADH + Oxygen + H+ <=> 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+
Toluene + NADH + H+ + Oxygen <=> 4-Cresol + NAD+ + H2O
ATP + NAD+ <=> 3'-Keto-3'-deoxy-ATP + NADH + H+
3'-Keto-3'-deoxy-ATP <=> 3'-Keto-3'-deoxy-AMP + Diphosphate
3'-Keto-3'-deoxy-AMP <=> 3'-Amino-3'-deoxy-AMP
3'-Amino-3'-deoxy-AMP + L-Tyrosine <=> N6,N6,O-Tridemethylpuromycin-5'-phosphate
N6,N6,O-Tridemethylpuromycin-5'-phosphate + Acetyl-CoA <=> N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + CoA
N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine
N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-O-demethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine
N-Acetyl-O-demethylpuromycin-5'-phosphate <=> N-Acetyl-O-demethylpuromycin
N-Acetyl-O-demethylpuromycin + S-Adenosyl-L-methionine <=> N-Acetylpuromycin + S-Adenosyl-L-homocysteine
N-Acetylpuromycin + H2O <=> Puromycin + Acetate
Sulcatol + NAD+ <=> Sulcatone + NADH + H+
sn-Glycerol 1-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+
sn-Glycerol 1-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+
O-Phospho-4-hydroxy-L-threonine + NAD+ <=> 2-Amino-3-oxo-4-phosphonooxybutyrate + NADH + H+
1,5-Anhydro-D-glucitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+
L-Idonate + NAD+ <=> 5-Dehydro-D-gluconate + NADH + H+
L-Idonate + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+
3-Methylbutanol + NAD+ <=> 3-Methylbutanal + NADH + H+
3-Methylbutanol + NADP+ <=> 3-Methylbutanal + NADPH + H+
dTDP-D-fucose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-glucose + NADPH + H+
2-C-Methyl-D-erythritol 4-phosphate + NADP+ <=> 1-Deoxy-D-xylulose 5-phosphate + NADPH + H+
(R)-2-Hydroxypropyl-CoM + NAD+ <=> 2-Oxopropyl-CoM + NADH + H+
(S)-2-Hydroxypropyl-CoM + NAD+ <=> 2-Oxopropyl-CoM + NADH + H+
Lophenol + NADP+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + NADPH + H+
GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
(S)-3-Sulfolactate + NAD+ <=> 3-Sulfopyruvate + NADH + H+
(S)-3-Sulfolactate + NADP+ <=> 3-Sulfopyruvate + NADPH + H+
Adenosine + 2 Oxygen + H2O <=> 9-Riburonosyladenine + 2 Hydrogen peroxide
Adenosine + Oxygen <=> 5'-Dehydroadenosine + Hydrogen peroxide
5'-Dehydroadenosine + Oxygen + H2O <=> 9-Riburonosyladenine + Hydrogen peroxide
Mannitol + Oxygen <=> D-Mannose + Hydrogen peroxide
4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O <=> Vanillate + NADH + H+
Coniferyl aldehyde + H2O + NAD+ <=> Ferulate + NADH + H+
Coniferyl aldehyde + H2O + NADP+ <=> Ferulate + NADPH + H+
Dihydrozeatin + NADP+ <=> Zeatin + NADPH + H+
Lathosterol + NADP+ <=> 5alpha-Cholesta-7,24-dien-3beta-ol + NADPH + H+
Reduced FMN + NAD+ <=> FMN + NADH + H+
Reduced FMN + NADP+ <=> FMN + NADPH + H+
Reduced riboflavin + NADP+ <=> Riboflavin + NADPH + H+
N,N-Dimethyl-1,4-phenylenediamine + Aniline + 2 NADP+ <=> para-(Dimethylamino)azobenzene + 2 NADPH + 2 H+
Coenzyme M + Acetoacetate + NADP+ <=> 2-Oxopropyl-CoM + CO2 + NADPH + H+
CoA + Glutathione + NADP+ <=> CoA-glutathione + NADPH + H+
2 Mycothiol + NAD+ <=> Mycothione + NADH + H+
2 Mycothiol + NADP+ <=> Mycothione + NADPH + H+
AMP + Sulfite + Glutathione disulfide <=> Adenylyl sulfate + 2 Glutathione
Linoleate + Oxygen <=> (9Z,12Z)-(11S)-11-Hydroperoxyoctadeca-9,12-dienoic acid
3-Hydroxy-1H-quinolin-4-one + Oxygen <=> Formylanthranilate + CO
3-Hydroxy-2-methyl-1H-quinolin-4-one + Oxygen <=> N-Acetylanthranilate + CO
Phytanoyl-CoA + 2-Oxoglutarate + Oxygen <=> 2-Hydroxyphytanoyl-CoA + Succinate + CO2
Leucocyanidin + 2-Oxoglutarate + Oxygen <=> Taxifolin + Succinate + CO2 + H2O
2 Nitric oxide + 2 Oxygen + NADH + H+ <=> 2 Nitrate + NAD+
2 Nitric oxide + 2 Oxygen + NADPH + H+ <=> 2 Nitrate + NADP+
Propylene + NADH + H+ + Oxygen <=> (2R)-1,2-Epoxypropane + NAD+ + H2O
Propylene + NADH + H+ + Oxygen <=> (S)-1,2-Epoxypropane + NAD+ + H2O
Acetone + HCO3- + 2 ATP + 3 H2O <=> Acetoacetate + 2 AMP + 4 Orthophosphate
Phosphonic acid + NAD+ + H2O <=> Orthophosphate + NADH + H+
Methylarsonate + 2 Glutathione <=> Methanearsonous acid + Glutathione disulfide + H2O
Dopamine + Secologanin <=> Deacetylipecoside + H2O
Dopamine + Secologanin <=> Deacetylisoipecoside + H2O
S-Adenosyl-L-methionine + 2,4,6-Trichlorophenol <=> S-Adenosyl-L-homocysteine + 2,4.6-Trichloroanisole
S-Adenosyl-L-methionine + 3'-Demethylstaurosporine <=> S-Adenosyl-L-homocysteine + Staurosporine
threo-3-Hydroxy-L-aspartate <=> Oxaloacetate + Ammonia
S-Adenosyl-L-methionine + (-)-Jasmonic acid <=> S-Adenosyl-L-homocysteine + Methyl jasmonate
S-Adenosyl-L-methionine + Cycloartenol <=> S-Adenosyl-L-homocysteine + (24R)-24-Methylcycloart-25-en-3-beta-ol
(R)-2-Hydroxypropyl-CoM <=> (2R)-1,2-Epoxypropane + Coenzyme M
(S)-2-Hydroxypropyl-CoM <=> (S)-1,2-Epoxypropane + Coenzyme M
S-Adenosyl-L-methionine + trans-Aconitate <=> S-Adenosyl-L-homocysteine + (E)-3-(Methoxycarbonyl)pent-2-enedioate
S-Adenosyl-L-methionine + trans-Aconitate <=> S-Adenosyl-L-homocysteine + (E)-2-(Methoxycarbonylmethyl)butenedioate
Geranyl diphosphate <=> (-)-alpha-Pinene + Diphosphate
Geranyl diphosphate <=> (-)-beta-Pinene + Diphosphate
alpha,alpha'-Trehalose 6-phosphate + Orthophosphate <=> D-Glucose 6-phosphate + beta-D-Glucose 1-phosphate
GDP-mannose + 3-Phospho-D-glycerate <=> GDP + 2-(alpha-D-Mannosyl)-3-phosphoglycerate
UDP-glucose + Hydroquinone <=> UDP + Arbutin
N-Cyclohexylformamide <=> Cyclohexyl isocyanide + H2O
Feruloyl-CoA + H2O <=> 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA
4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA
3-Sulfopyruvate <=> Sulfoacetaldehyde + CO2
UDP-glucose + Sulfite <=> UDP-6-sulfoquinovose + H2O
S-Adenosyl-L-methionine + 24-Methylenelophenol <=> S-Adenosyl-L-homocysteine + 24-Ethylidenelophenol
3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> 4-Hydroxymandelate + CO2
5-PP-InsP5 + H2O <=> Phytic acid + Orthophosphate
Thiocyanate + 2 H2O <=> Carbonyl sulfide + Ammonia + HO-
Maleimide + H2O <=> Maleamate
N-Carbamoyl-L-amino acid + H2O <=> L-Amino acid + Ammonia + CO2
(R)-Mandelamide + H2O <=> (R)-Mandelate + Ammonia
Limonene-1,2-epoxide + H2O <=> Limonene-1,2-diol
6-O-(beta-D-Xylopyranosyl)-beta-D-glucopyranoside + H2O <=> 6-O-(beta-D-Xylopyranosyl)-beta-D-glucopyranose + Alcohol
(2R)-O-Phospho-3-sulfolactate + H2O <=> (2R)-3-Sulfolactate + Orthophosphate
2-(alpha-D-Mannosyl)-3-phosphoglycerate + H2O <=> 2-O-(alpha-D-Mannosyl)-D-glycerate + Orthophosphate
2-(alpha-D-Glucosyl)-sn-glycerol 3-phosphate + H2O <=> 2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate
3-(Acyloxy)acyl group of bacterial toxin + 2 H2O <=> 3-Hydroxyacyl group of bacterial toxin + 2 Fatty acid
CDP-diacylglycerol + Choline <=> CMP + Phosphatidylcholine
ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Poly[(R)-3-hydroxyoctanoate]n + H2O <=> Poly[(R)-3-hydroxyoctanoate]n + Poly[(R)-3-hydroxyoctanoate]x
Poly[(R)-3-hydroxybutanoate]n-x + H2O <=> Poly[(R)-3-hydroxybutanoate]n-x + Poly[(R)-3-hydroxybutanoate]x
3'-Phosphoadenylyl sulfate + [Heparan sulfate]-glucosamine <=> Adenosine 3',5'-bisphosphate + [Heparan sulfate]-glucosamine 3-sulfate
ATP + Phytic acid <=> ADP + 1-Diphosinositol pentakisphosphate
ATP + D-myo-Inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-Inositol 1,4,5,6-tetrakisphosphate
ATP + 1D-myo-Inositol 1,4,5,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
ATP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
ATP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
ADP + D-Glucose <=> AMP + D-Glucose 6-phosphate
ADP + D-Fructose 6-phosphate <=> AMP + D-Fructose 1,6-bisphosphate
ATP + Deoxynucleoside <=> ADP + Deoxynucleoside 5'-phosphate
Sirohydrochlorin + Cobalt ion <=> Cobalt-sirohydrochlorin + 2 H+
Cobalt-sirohydrochlorin + S-Adenosyl-L-methionine <=> Cobalt-factor III + S-Adenosyl-L-homocysteine
Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine
Cobalt-precorrin 4 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 5A + S-Adenosyl-L-homocysteine
Cobalt-precorrin 5 + S-Adenosyl-L-methionine + H2O <=> Cobalt-precorrin 6 + S-Adenosyl-L-homocysteine + Acetaldehyde
Cobalt-precorrin 6 + NADH + H+ <=> Cobalt-dihydro-precorrin 6 + NAD+
Cobalt-dihydro-precorrin 6 + 2 S-Adenosyl-L-methionine <=> Cobalt-precorrin 8 + 2 S-Adenosyl-L-homocysteine + CO2
Cobalt-precorrin 8 <=> Cobyrinate
Protein N(pi)-phospho-L-histidine + D-Sorbitol <=> Protein histidine + Sorbitol 6-phosphate
Inosine + Oxygen <=> 9-Riburonosylhypoxanthine + H2O
2 5'-Oxoinosine + Oxygen <=> 2 9-Riburonosylhypoxanthine
2-Keto-D-gluconic acid + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+
4,21-Dehydrocorynantheine aldehyde <=> 4,21-Dehydrogeissoschizine
Polyneuridine aldehyde + H2O <=> 16-Epivellosimine + CO2 + Methanol
16-Epivellosimine <=> Vellosimine
10-Deoxysarpagine + NADP+ <=> Vellosimine + NADPH + H+
2-Hydroxy-vitamin K + Oxidized dithiothreitol <=> Vitamin K1 epoxide + Dithiothreitol
Xylitol + NAD+ <=> L-Xylulose + NADH + H+
S-Adenosyl-L-methionine + Secologanate <=> S-Adenosyl-L-homocysteine + Secologanin
Glycocholate + H2O <=> Cholic acid + Glycine
3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + 2 H+ <=> Deoxycholic acid
O-Phospho-4-hydroxy-L-threonine + NAD+ <=> 3-Amino-2-oxopropyl phosphate + NADH + H+ + CO2
3-Amino-2-oxopropyl phosphate + 1-Deoxy-D-xylulose 5-phosphate <=> Pyridoxine phosphate + Orthophosphate + 2 H2O
Pyridoxamine + 2-Oxoglutarate <=> Pyridoxal + D-Glutamate
Glycolaldehyde + 2-Oxobutanoate + Alanine <=> Pyridoxine
Phenylacetyl-CoA + Glycine <=> Phenylacetylglycine + CoA
Ethylene oxide + H2O <=> Ethylene glycol
Phenanthrene + NADH + H+ + Oxygen <=> (+)-cis-3,4-Dihydrophenanthrene-3,4-diol + NAD+
Strictosidine aglycone <=> Dialdehyde
Dialdehyde + H+ <=> 4,21-Dehydrocorynantheine aldehyde + H2O
4,21-Dehydrogeissoschizine <=> Cathenamine
Cathenamine + NADPH + H+ <=> Ajmalicine + NADP+
Cathenamine + NADPH + H+ <=> Tetrahydroalstonine + NADP+
L-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate
4,21-Dehydrogeissoschizine <=> Stemmadenine
Stemmadenine <=> Tabersonine
Stemmadenine <=> Catharanthine
16-Methoxytabersonine + H2O <=> 16-Methoxy-2,3-dihydro-3-hydroxytabersonine
Desacetoxyvindoline + 2-Oxoglutarate + Oxygen <=> Deacetylvindoline + Succinate + CO2
Vindoline + Catharanthine <=> 3',4'-Anhydrovinblastine
3',4'-Anhydrovinblastine <=> Vinblastine
Vinblastine <=> Vincristine
D-Alanine + H2O + Oxygen <=> Pyruvate + Ammonia + Hydrogen peroxide
Sarcosine + H2O + Oxygen <=> Glyoxylate + Methylamine + Hydrogen peroxide
N-Ethylglycine + H2O + Oxygen <=> Glyoxylate + Ethylamine + Hydrogen peroxide
2-Hydroxy-cis-hex-2,4-dienoate + H2O <=> 4-Hydroxy-2-oxohexanoic acid
2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + H2O <=> Formate + 2-Hydroxy-cis-hex-2,4-dienoate
Tabersonine + NADPH + H+ + Oxygen <=> Lochnericine + NADP+ + H2O
Lochnericine <=> Horhammericine
Tabersonine <=> Horhammericine
Tabersonine <=> Minovincinine
Minovincinine + Acetyl-CoA <=> Echitovenine + CoA
19-Hydroxytabersonine <=> Horhammericine
Tabersonine <=> 19-Hydroxytabersonine
4,21-Dehydrogeissoschizine <=> 19-epi-Cathenamine
19-epi-Cathenamine + NADPH + H+ <=> 19-epi-Ajmalicine + NADP+
Acetyl-CoA + 16-Epivellosimine <=> CoA + Vinorine
1,2-Dihydrovomilenine + NADP+ <=> Vomilenine + NADPH + H+
17-O-Acetylnorajmaline + NADP+ <=> 1,2-Dihydrovomilenine + NADPH + H+
17-O-Acetylnorajmaline + H2O <=> Norajmaline + Acetate
Norajmaline + S-Adenosyl-L-methionine <=> Ajmaline + S-Adenosyl-L-homocysteine
UDP-glucose + Vomilenine <=> UDP + Raucaffricine
16-Hydroxytabersonine + S-Adenosyl-L-methionine <=> 16-Methoxytabersonine + S-Adenosyl-L-homocysteine + H+
Tabersonine <=> Lochnerinine
Deacetylipecoside <=> Demethylalangiside
Demethylalangiside <=> Alangiside
Deacetylisoipecoside <=> Demethylisoalangiside
Demethylisoalangiside <=> Isoalangiside
Protoemetine <=> Tubulosine
Protoemetine + Tryptamine <=> Deoxytubulosine
Deoxytubulosine <=> Alangimarckine
Protoemetine <=> Ankorine
Loganate <=> 10-Deoxygeniposidic acid
10-Deoxygeniposidic acid <=> Geniposidic acid
Geniposidic acid <=> Asperuloside
beta-D-Mannosylphosphodecaprenol + 1,6-alpha-D-Mannosyloligosaccharide <=> Decaprenol phosphate + 1,6-alpha-D-Mannosyl-1,6-alpha-D-mannosyloligosaccharide
UDP-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
UDP-glucose + Indoxyl <=> UDP + Indican
5-Hydroxyisourate + H+ + H2O <=> (R)(-)-Allantoin + CO2
5-Hydroxyisourate + H+ + H2O <=> (S)-Allantoin + CO2
(+)-trans-Carveol + NAD+ <=> (+)-(S)-Carvone + NADH + H+
Geranyl diphosphate <=> (R)-Limonene + Diphosphate
alpha-Amino acid + H2O + Oxygen <=> 2-Oxo acid + Ammonia + Hydrogen peroxide
L-Serine + NADP+ <=> 2-Aminomalonate semialdehyde + NADPH + H+
alpha-Amino acid <=> 2-Oxo acid + Ammonia
alpha-Amino acid <=> 2,3-Ene acid + Ammonia
Amide + H2O <=> Carboxylate + Ammonia
Methylamine + Oxygen + H2O <=> Formaldehyde + Ammonia + Hydrogen peroxide
3beta-Hydroxy-5beta-pregnane-20-one + NADP+ <=> 5beta-Pregnane-3,20-dione + NADPH + H+
L-Allothreonine <=> Glycine + Acetaldehyde
(R,R)-Tartaric acid + NAD+ <=> 2-Hydroxy-3-oxosuccinate + NADH + H+
Lumirhodopsin <=> Metarhodopsin
ent-Kaurene <=> Aconitine
ent-Kaurene <=> Veatchine
2 trans,trans-Farnesyl diphosphate + NADPH + H+ <=> Squalene + 2 Diphosphate + NADP+
2 I-Urobilinogen + Oxygen <=> 2 Urobilin + 2 H2O
2 L-Urobilinogen + Oxygen <=> 2 L-Urobilin + 2 H2O
D-Urobilinogen + 2 H+ <=> I-Urobilinogen
I-Urobilinogen + 4 H+ <=> L-Urobilinogen
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + Oxygen <=> 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + Oxygen <=> 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O
13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + Oxygen <=> Divinylprotochlorophyllide + NADP+ + 2 H2O
Magnesium protoporphyrin monomethyl ester + S-Adenosyl-L-methionine + H2O <=> 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine <=> 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine
13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine <=> Divinylprotochlorophyllide + 5'-Deoxyadenosine + L-Methionine
Divinylprotochlorophyllide + 2 H+ <=> Protochlorophyllide
Divinyl chlorophyllide a + NADPH + H+ <=> Chlorophyllide + NADP+
Chlorophyllide + Phytyl diphosphate <=> Chlorophyll a + Diphosphate
Divinyl chlorophyllide a + NADP+ <=> Divinylprotochlorophyllide + NADPH + H+
Divinyl chlorophyllide a <=> Divinylchlorophyll a
Divinylchlorophyll a <=> Chlorophyll a
Geranylgeranyl diphosphate <=> Copalyl diphosphate
Copalyl diphosphate <=> Pimaradiene + Diphosphate
Copalyl diphosphate <=> (-)-Abietadiene + Diphosphate
Copalyl diphosphate <=> Levopimaradiene + Diphosphate
Copalyl diphosphate <=> Neoabietadiene + Diphosphate
Copalyl diphosphate <=> Palustradiene + Diphosphate
Geranylgeranyl diphosphate <=> Taxa-4(5),11(12)-diene + Diphosphate
Taxa-4(20),11(12)-dien-5alpha-ol + Acetyl-CoA <=> Taxa-4(20),11(12)-dien-5alpha-yl acetate + CoA
10-Deacetyl-2-debenzoylbaccatin III + Benzoyl-CoA <=> 10-Deacetylbaccatin III + CoA
10-Deacetylbaccatin III + Acetyl-CoA <=> Baccatin III + CoA
Geranylgeranyl diphosphate <=> 9alpha-Copalyl diphosphate
9alpha-Copalyl diphosphate + H2O <=> Aphidicolan-16beta-ol + Diphosphate
9alpha-Copalyl diphosphate <=> Aphidicol-16-ene
9alpha-Copalyl diphosphate <=> Aphidicol-15-ene
Aphidicolan-16beta-ol <=> Aphidicolin
Aphidicol-16-ene <=> Aphidicolin
Taxa-4(20),11(12)-dien-5alpha,13alpha-diol <=> 10-Deacetyl-2-debenzoylbaccatin III
10beta,14beta-Dihydroxytaxa-4(20),11-dien-5alpha-yl acetate <=> 10-Deacetyl-2-debenzoylbaccatin III
Baccatin III <=> Paclitaxel
Geranylgeranyl diphosphate <=> Cembrene
Gibberellin A12 + 2-Oxoglutarate + Oxygen <=> Gibberellin A15 open lactone + Succinate + CO2
Gibberellin A15 open lactone + 2-Oxoglutarate + Oxygen <=> Gibberellin A24 + Succinate + CO2 + H2O
Gibberellin A14 <=> Gibberellin A37 open lactone
Gibberellin A37 open lactone <=> Gibberellin A36
Gibberellin A24 <=> Gibberellin A9 + CO2
Gibberellin A36 <=> Gibberellin A4 + CO2
Gibberellin A12 aldehyde <=> Gibberellin A53 aldehyde
Gibberellin A12 <=> Gibberellin A53
Gibberellin A15 open lactone <=> Gibberellin A44 diacid
Gibberellin A24 <=> Gibberellin A19
Gibberellin A9 <=> Gibberellin A20
Gibberellin A12 <=> Gibberellin A14
Gibberellin A15 open lactone <=> Gibberellin A37 open lactone
Gibberellin A24 + 2-Oxoglutarate + Oxygen <=> Gibberellin A36 + Succinate + CO2
Gibberellin A9 + 2-Oxoglutarate + Oxygen <=> Gibberellin A4 + Succinate + CO2
Gibberellin A9 + 2-Oxoglutarate + Oxygen <=> Gibberellin A51 + Succinate + CO2
Gibberellin A4 + 2-Oxoglutarate + Oxygen <=> Gibberellin A34 + Succinate + CO2
Gibberellin A14 aldehyde <=> Gibberellin A14
Gibberellin A53 aldehyde <=> Gibberellin A53
Gibberellin A12 aldehyde <=> Gibberellin A14 aldehyde
Gibberellin A34 <=> Gibberellin A34-catabolite
Gibberellin A51 <=> Gibberellin A51-catabolite
Gibberellin A29 <=> Gibberellin A29-catabolite
Gibberellin A8 <=> Gibberellin A8-catabolite
Gibberellin A20 <=> Gibberellin A5
Gibberellin A5 <=> Gibberellin A3
Gibberellin A5 <=> Gibberellin A6
Gibberellin A9 <=> 2,3-Dehydro-gibberellin A9
2,3-Dehydro-gibberellin A9 <=> Gibberellin A7
Levopimaradiene <=> Levopimarinol
Neoabietadiene <=> Neoabietinol
Levopimarinol <=> Levopimarinal
Neoabietinol <=> Neoabietal
Abietal + H2O + NAD+ <=> Abietate + NADH + 2 H+
Levopimarinal <=> Levopimaric acid
Neoabietal <=> Neoabietic acid
Isopenicillin N + Acyl-CoA + H2O <=> Penicillin + CoA + L-2-Aminoadipate
Penicillin + H2O <=> Penicilloic acid
CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine
O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate + NDP-N-methyl-L-glucosamine <=> Dihydrostreptomycin 6-phosphate + NDP
Perillyl aldehyde + H2O + NAD+ <=> Perillic acid + NADH + H+
Perillic acid + CoA + ATP <=> Perillyl-CoA + H2O + ADP + Orthophosphate
Perillic acid + CoA + ATP <=> Perillyl-CoA + H2O + AMP + Diphosphate
Perillyl-CoA + H2O <=> 2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA
4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA + H2O <=> 3-Isopropenylpimelyl-CoA
(4R,6R)-cis-Carveol <=> (-)-Carvone
(4S,6S)-cis-Carveol <=> (+)-(S)-Carvone
(1R,2R,4R)-Dihydrocarveol + NAD+ <=> (1R,4R)-Dihydrocarvone + NADH + H+
(1R,2R,4S)-Iso-dihydrocarveol + NAD+ <=> (1R,4S)-Iso-dihydrocarvone + NADH + H+
(1R,2S,4R)-Neo-dihydrocarveol + NAD+ <=> (1R,4R)-Dihydrocarvone + NADH + H+
(1R,2S,4S)-Neoiso-dihydrocarveol + NAD+ <=> (1R,4S)-Iso-dihydrocarvone + NADH + H+
(1R,4R)-Dihydrocarvone <=> (1S,4R)-Iso-dihydrocarvone
(1R,4S)-Iso-dihydrocarvone <=> (1S,4S)-Dihydrocarvone
(1S,2S,4R)-Iso-dihydrocarveol + NAD+ <=> (1S,4R)-Iso-dihydrocarvone + NADH + H+
(1S,2S,4S)-Dihydrocarveol + NAD+ <=> (1S,4S)-Dihydrocarvone + NADH + H+
(1S,2R,4R)-Neoiso-dihydrocarveol + NAD+ <=> (1S,4R)-Iso-dihydrocarvone + NADH + H+
(1S,2R,4S)-Neo-dihydrocarveol + NAD+ <=> (1S,4S)-Dihydrocarvone + NADH + H+
(1R,4R)-Dihydrocarvone + NADPH + Oxygen + H+ <=> (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O
(1R,4S)-Iso-dihydrocarvone + NADPH + Oxygen + H+ <=> (4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O
(1S,4R)-Iso-dihydrocarvone + NADPH + Oxygen + H+ <=> (3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + NADP+ + H2O
(1S,4S)-Dihydrocarvone + NADPH + Oxygen + H+ <=> (3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + NADP+ + H2O
(4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + H2O <=> (3R)-6-Hydroxy-3-isopropenyl-heptanoate
(3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O <=> (5R)-6-Hydroxy-5-isopropenyl-2-methylhexanoate
(4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + H2O <=> (3S)-6-Hydroxy-3-isopropenyl-heptanoate
(3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O <=> (5S)-6-Hydroxy-5-isopropenyl-2-methylhexanoate
(3R)-6-Hydroxy-3-isopropenyl-heptanoate <=> (3R)-3-Isopropenyl-6-oxoheptanoate
(3S)-6-Hydroxy-3-isopropenyl-heptanoate <=> (3S)-3-Isopropenyl-6-oxoheptanoate
(3R)-3-Isopropenyl-6-oxoheptanoate + CoA + ATP <=> (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA + H2O + ADP + Orthophosphate
(3S)-3-Isopropenyl-6-oxoheptanoate <=> (3S)-3-Isopropenyl-6-oxoheptanoyl-CoA
(R)-Limonene + NADH + Oxygen + H+ <=> Limonene-1,2-epoxide + NAD+ + H2O
Limonene-1,2-diol + NAD+ <=> (1S,4R)-1-Hydroxy-2-oxolimonene + NADH + H+
(1S,4R)-1-Hydroxy-2-oxolimonene + NADPH + Oxygen + H+ <=> (4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O
Pinocarveol <=> Pinocarvone + H+
alpha-Pinene + NADH + H+ + Oxygen <=> alpha-Pinene-oxide + NAD+ + H2O
(Z)-2-Methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O <=> cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid + NADH + H+
trans-2-Methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O <=> trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid + NADH + H+
cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoA <=> cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + Diphosphate
trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoA <=> trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + Diphosphate
cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + H2O <=> 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA
trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + H2O <=> 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA
3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ <=> 2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH + H+
2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoA <=> 3-Isopropylbut-3-enoyl-CoA + Propanoyl-CoA
3-Isopropylbut-3-enoyl-CoA + H2O <=> 3-Isopropyl-3-butenoic acid + CoA
(-)-Isopiperitenone + NADPH + H+ <=> (+)-cis-Isopulegone + NADP+
(+)-cis-Isopulegone <=> Pulegone
Pulegone + NADPH + H+ <=> (-)-Menthone + NADP+
Pulegone + NADPH + H+ <=> (+)-Isomenthone + NADP+
Geranyl diphosphate + H2O <=> (-)-alpha-Terpineol + Diphosphate
(-)-alpha-Terpineol <=> 1,8-Cineole
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate <=> dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate
dTDP-4-oxo-6-deoxy-D-glucose <=> 3,6-Dideoxy-3-oxo-dTDP-D-glucose
dTDP-3-oxo-4,6-dideoxy-D-glucose + L-Glutamate <=> dTDP-3-amino-3,4,6-trideoxy-D-glucose + 2-Oxoglutarate
dTDP-3-amino-3,4,6-trideoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-desosamine + 2 S-Adenosyl-L-homocysteine
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H2O
dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+ <=> dTDP-L-olivose + NADP+
dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose + NADPH + H+ <=> dTDP-L-mycarose + NADP+
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-4-oxo-6-deoxy-D-allose
dTDP-6-deoxy-D-allose + NAD+ <=> dTDP-4-oxo-6-deoxy-D-allose + NADH + H+
dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose <=> Maltol + dTDP
dTDP-4-dehydro-beta-L-rhamnose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
dTDP-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-D-olivose
Tylactone + dTDP-D-mycaminose <=> 5-O-beta-D-Mycaminosyltylactone + dTDP
5-O-beta-D-Mycaminosyltylonolide + dTDP-6-deoxy-D-allose <=> Demethyllactenocin + dTDP
Demethyllactenocin + dTDP-L-mycarose <=> Demethylmacrocin + dTDP
Oleandolide + dTDP-L-olivose <=> L-Olivosyl-oleandolide + dTDP
L-Olivosyl-oleandolide + S-Adenosyl-L-methionine <=> L-Oleandrosyl-oleandolide + S-Adenosyl-L-homocysteine
L-Oleandrosyl-oleandolide + dTDP-D-desosamine <=> Oleandomycin + dTDP
10-Deoxymethynolide + dTDP-D-desosamine <=> 10-Deoxymethymycin + dTDP
Narbonolide + dTDP-D-desosamine <=> Narbomycin + dTDP
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2a'' aglycone + NADP+ + H2O
(S)-2,3-Epoxysqualene <=> Lupeol
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''1a'' aglycone + NADP+ + H2O
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2b'' aglycone + NADP+ + H2O
(S)-2,3-Epoxysqualene <=> beta-Amyrin
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''1b'' aglycone + NADP+ + H2O
(S)-2,3-Epoxysqualene <=> alpha-Amyrin
5-Oxoavermectin ''2a'' aglycone + NADPH + H+ <=> Avermectin B2a aglycone + NADP+
5-Oxoavermectin ''1a'' aglycone + NADPH + H+ <=> Avermectin B1a aglycone + NADP+
5-Oxoavermectin ''2b'' aglycone + NADPH + H+ <=> Avermectin B2b aglycone + NADP+
5-Oxoavermectin ''1b'' aglycone + NADPH + H+ <=> Avermectin B1b aglycone + NADP+
Avermectin B2a aglycone + S-Adenosyl-L-methionine <=> Avermectin A2a aglycone + S-Adenosyl-L-homocysteine
Avermectin B1a aglycone + S-Adenosyl-L-methionine <=> Avermectin A1a aglycone + S-Adenosyl-L-homocysteine
Avermectin B2b aglycone + S-Adenosyl-L-methionine <=> Avermectin A2b aglycone + S-Adenosyl-L-homocysteine
Avermectin B1b aglycone + S-Adenosyl-L-methionine <=> Avermectin A1b aglycone + S-Adenosyl-L-homocysteine
Avermectin B2a aglycone + dTDP-L-oleandrose <=> Avermectin B2a monosaccharide + dTDP
Avermectin B2a monosaccharide + dTDP-L-oleandrose <=> Avermectin B2a + dTDP
Avermectin A2a aglycone + dTDP-L-oleandrose <=> Avermectin A2a monosaccharide + dTDP
Avermectin A2a monosaccharide + dTDP-L-oleandrose <=> Avermectin A2a + dTDP
Avermectin B1a aglycone + dTDP-L-oleandrose <=> Avermectin B1a monosaccharide + dTDP
Avermectin B1a monosaccharide + dTDP-L-oleandrose <=> Avermectin B1a + dTDP
Avermectin A1a aglycone + dTDP-L-oleandrose <=> Avermectin A1a monosaccharide + dTDP
Avermectin A1a monosaccharide + dTDP-L-oleandrose <=> Avermectin A1a + dTDP
Avermectin B2b aglycone + dTDP-L-oleandrose <=> Avermectin B2b monosaccharide + dTDP
Avermectin B2b monosaccharide + dTDP-L-oleandrose <=> Avermectin B2b + dTDP
Avermectin A2b aglycone + dTDP-L-oleandrose <=> Avermectin A2b monosaccharide + dTDP
Avermectin A2b monosaccharide + dTDP-L-oleandrose <=> Avermectin A2b + dTDP
Avermectin B1b aglycone + dTDP-L-oleandrose <=> Avermectin B1b monosaccharide + dTDP
Avermectin B1b monosaccharide + dTDP-L-oleandrose <=> Avermectin B1b + dTDP
Avermectin A1b aglycone + dTDP-L-oleandrose <=> Avermectin A1b monosaccharide + dTDP
Avermectin A1b monosaccharide + dTDP-L-oleandrose <=> Avermectin A1b + dTDP
Soyasapogenol B <=> Soyasaponin I
beta-Amyrin + Oxygen <=> Soyasapogenol B
(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid <=> (5Z,7E,9E,14Z,17Z)-Icosapentaenoate
Megalomicin A <=> Megalomicin B
Megalomicin A <=> Megalomicin C1
Megalomicin A <=> Megalomicin C2
Erythromycin C + dTDP-L-megosamine <=> Megalomicin A + dTDP
dTDP-glucose <=> dTDP-4-oxo-6-deoxy-D-glucose + H2O
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-4-dehydro-beta-L-rhamnose
(3R)-3-Isopropenyl-6-oxoheptanoate + CoA + ATP <=> (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA + H2O + AMP + Diphosphate
Sphingosine 1-phosphate <=> Ethanolamine phosphate + Hexadecenal
Acyl-CoA + Sphinganine <=> CoA + Dihydroceramide
Dihydroceramide + H2O <=> Fatty acid + Sphinganine
Sphinganine 1-phosphate + H2O <=> Sphinganine + Orthophosphate
Sphingosine 1-phosphate + H2O <=> Sphingosine + Orthophosphate
Ceramide 1-phosphate + H2O <=> N-Acylsphingosine + Orthophosphate
trans,trans-Farnesyl diphosphate <=> Vetispiradiene + Diphosphate
C26-CoA + Phytosphingosine <=> CoA + Phytoceramide
Phytoceramide + H2O <=> Fatty acid + Phytosphingosine
L-Threonine O-3-phosphate <=> D-1-Aminopropan-2-ol O-phosphate + CO2
L-Threonine + ATP <=> L-Threonine O-3-phosphate + ADP
Leucocyanidin + NADPH + H+ <=> (+)-Catechin + NADP+ + H2O
Leucodelphinidin + NADPH + H+ <=> (+)-Gallocatechin + NADP+ + H2O
Pelargonidin + UDP-glucose <=> Pelargonidin 3-O-glucoside + UDP
Cyanidin + UDP-glucose <=> Cyanidin 3-O-glucoside + UDP
Delphinidin + UDP-glucose <=> Delphinidin 3-O-glucoside + UDP
Dihydromyricetin + 2-Oxoglutarate + Oxygen <=> Myricetin + Succinate + CO2 + H2O
cis-3,4-Leucopelargonidin + 2-Oxoglutarate + Oxygen <=> Dihydrokaempferol + Succinate + CO2 + H2O
(-)-Epiafzelechin + 2 NADP+ <=> Pelargonidin + 2 NADPH + H+
(-)-Epicatechin + 2 NADP+ <=> Cyanidin + 2 NADPH + H+
(-)-Epigallocatechin + 2 NADP+ <=> Delphinidin + 2 NADPH + H+
Cyanidin 3-O-glucoside + p-Coumaroyl-CoA <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside + CoA
Cyanidin 3,5-O-diglucoside + p-Coumaroyl-CoA <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + CoA
Cyanidin 3-O-glucoside + UDP-glucose <=> Cyanidin 3,5-O-diglucoside + UDP
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside + UDP-glucose <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + UDP
Cyanidin 3-O-glucoside <=> Peonidin 3-O-glucoside
Delphinidin 3-O-glucoside <=> Petunidin 3-O-glucoside
Delphinidin 3-O-glucoside <=> Malvidin 3-O-glucoside
Pentahydroxyflavanone + 2-Oxoglutarate + Oxygen <=> Tricetin + Succinate + CO2 + H2O
Naringenin <=> Genistein
Liquiritigenin <=> Daidzein
Isoliquiritigenin <=> Liquiritigenin
Adenosyl cobinamide + GTP <=> Adenosyl cobinamide phosphate + GDP
2'-Hydroxyformononetin + NADPH + H+ <=> (-)-Vestitone + NADP+
2'-Hydroxybiochanin A + NADPH + H+ <=> Ferreirin + NADP+
Daidzein + S-Adenosyl-L-methionine <=> Formononetin + S-Adenosyl-L-homocysteine
(-)-Vestitone <=> Medicarpin
5-Hydroxyferuloyl-CoA + NADPH + H+ <=> 5-Hydroxyconiferaldehyde + CoA + NADP+
5-Hydroxyconiferaldehyde + NADPH + H+ <=> 5-Hydroxyconiferyl alcohol + NADP+
Caffeic aldehyde + NADPH + H+ <=> Caffeyl alcohol + NADP+
Coniferyl aldehyde + NADPH + H+ + Oxygen <=> 5-Hydroxyconiferaldehyde + NADP+ + H2O
Coniferyl alcohol + NADPH + H+ + Oxygen <=> 5-Hydroxyconiferyl alcohol + NADP+ + H2O
Caffeic aldehyde + S-Adenosyl-L-methionine <=> Coniferyl aldehyde + S-Adenosyl-L-homocysteine
Caffeyl alcohol + S-Adenosyl-L-methionine <=> Coniferyl alcohol + S-Adenosyl-L-homocysteine
5-Hydroxyconiferaldehyde + S-Adenosyl-L-methionine <=> Sinapoyl aldehyde + S-Adenosyl-L-homocysteine
5-Hydroxyconiferyl alcohol + S-Adenosyl-L-methionine <=> Sinapyl alcohol + S-Adenosyl-L-homocysteine
5-Hydroxyferuloyl-CoA + S-Adenosyl-L-methionine <=> Sinapoyl-CoA + S-Adenosyl-L-homocysteine
4-Hydroxycinnamyl aldehyde <=> Caffeic aldehyde
4-Coumaryl alcohol <=> Caffeyl alcohol
5-Hydroxyferulic acid + CoA + ATP <=> 5-Hydroxyferuloyl-CoA + AMP + Diphosphate
Feruloyl-CoA <=> 5-Hydroxyferuloyl-CoA
UDP-3-ketoglucose + L-Glutamate <=> UDP-kanosamine + 2-Oxoglutarate
UDP-kanosamine <=> Kanosamine
ATP + Kanosamine <=> ADP + Kanosamine 6-phosphate
Kanosamine 6-phosphate <=> Aminofructose 6-phosphate
Aminofructose 6-phosphate + D-Ribose 5-phosphate <=> Iminoerythrose 4-phosphate + Sedoheptulose 7-phosphate
Iminoerythrose 4-phosphate + Phosphoenolpyruvate + H2O <=> AminoDAHP + Orthophosphate
AminoDAHP <=> AminoDHQ + Orthophosphate
AminoDHQ <=> 5-Amino-5-deoxy-3-dehydroshikimate + H2O
UDP-glucose + NAD+ <=> UDP-3-ketoglucose + NADH + H+
5-Amino-5-deoxy-3-dehydroshikimate <=> 3-Amino-5-hydroxybenzoate + H2O
Proansamycin X <=> Protorifamycin I
Protorifamycin I <=> Rifamycin W
Proansamycin X <=> 34a-Deoxy-rifamycin W
Rifamycin <=> Rifamycin B
5-Hydroxyisourate + H2O <=> 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
Isochorismate <=> Salicylate + Pyruvate
Chorismate <=> Salicylate + Pyruvate
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate <=> (S)-Allantoin + CO2
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+ <=> (R)(-)-Allantoin + CO2
Naringenin + NADPH + H+ <=> Apiforol + NADP+
Kaempferol + UDP-glucose <=> Kaempferol 3-O-glucoside + UDP
5,6-Indolequinone-2-carboxylic acid <=> Eumelanin
5,10-Methylenetetrahydrofolate + dUMP + NADPH + H+ <=> Tetrahydrofolate + dTMP + NADP+
3-Cyano-L-alanine <=> 3-Aminopropiononitrile + CO2
cis-3,4-Leucopelargonidin + NADPH + H+ <=> Afzelechin + NADP+ + H2O
Gibberellin A4 <=> Gibberellin A7
Gibberellin A7 <=> Gibberellin A3
Gibberellin A4 <=> Gibberellin A1
D-Glucose + Ubiquinone <=> D-Glucono-1,5-lactone + Ubiquinol
cis-1,2-Cyclohexanediol + NAD+ <=> 2-Hydroxycyclohexan-1-one + NADH
NADPH + 2-Hydroxycyclohexan-1-one + H+ + Oxygen <=> NADP+ + 1-Oxa-2-oxo-3-hydroxycycloheptane + H2O
3,5-Dihydroxyphenylacetyl-CoA + Oxygen <=> 3,5-Dihydroxyphenylglyoxylate + CoA
4-Hydroxyphenylglyoxylate + L-Tyrosine <=> L-4-Hydroxyphenylglycine + 3-(4-Hydroxyphenyl)pyruvate
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + S-Adenosyl-L-methionine <=> dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose + S-Adenosyl-L-homocysteine
dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose <=> dTDP-L-4-oxovancosamine
dTDP-L-4-oxovancosamine + NADPH + H+ <=> dTDP-L-epivancosamine + NADP+
dTDP-L-4-oxovancosamine <=> dTDP-L-vancosamine
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + L-Glutamate <=> dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + 2-Oxoglutarate
3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> (S)-4-Hydroxymandelate + CO2
(S)-4-Hydroxymandelate + Oxygen <=> 4-Hydroxyphenylglyoxylate + Hydrogen peroxide
3,5-Dihydroxy-phenylglycine + 2-Oxoglutarate <=> 3,5-Dihydroxyphenylglyoxylate + L-Glutamate
18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + NADPH + H+ <=> C-9 Reduced nonaketamide + NADP+
10 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] + 10 CO2 + 10 CoA
Tetrangomycin <=> Tetrangulol + H2O
Tetrangulol <=> 8-O-Methyltetrangulol
8-O-Methyltetrangulol <=> 19-Hydroxy-8-O-methyltetrangulol
Tetrangulol <=> 19-Hydroxytetrangulol
19-Hydroxytetrangulol <=> 19-Hydroxy-8-O-methyltetrangulol
19-Hydroxy-8-O-methyltetrangulol <=> PD116740
Tetrangomycin <=> Rabelomycin
Urdamycinone B + dTDP-beta-L-rhodinose <=> 100-1 + dTDP
100-1 + dTDP-D-olivose <=> Urdamycin B + dTDP
Urdamycinone B <=> 104-2
104-2 + dTDP-beta-L-rhodinose + dTDP-D-olivose <=> 124-1 + 2 dTDP
Urdamycinone F <=> Aquayamycin + H2O
Aquayamycin + dTDP-beta-L-rhodinose <=> 100-2 + dTDP
100-2 + dTDP-beta-L-rhodinose <=> Urdamycin G + dTDP
Urdamycin G + dTDP-D-olivose <=> Urdamycin A + dTDP
Jadomycin A <=> Jadomycin B
Dehydrorabelomycin <=> Kinobscurinone
Kinobscurinone <=> Stealthin C
Stealthin C <=> Prekinamycin
Prekinamycin <=> Kinamycin D
Nogalonate + S-Adenosyl-L-methionine <=> Methyl nogalonate + S-Adenosyl-L-homocysteine
Methyl nogalonate <=> Auraviketone
Auraviketone + NADPH + H+ <=> Auramycinone + NADP+
Methyl nogalonate <=> Dihydro-NAME
12-Deoxyaklanonic acid + Oxygen <=> Aklanonate + H2O
Aklanonate + S-Adenosyl-L-methionine <=> Methyl aklanonate + S-Adenosyl-L-homocysteine
Methyl aklanonate <=> Aklaviketone
Aklaviketone + NADPH + H+ <=> Aklavinone + NADP+
Aklavinone + NADPH + H+ + Oxygen <=> epsilon-Rhodomycinone + NADP+ + H2O
epsilon-Rhodomycinone + dTDP-beta-L-daunosamine <=> Rhodomycin D + dTDP
Rhodomycin D + H2O <=> 10-Carboxy-13-deoxycarminomycin + Methanol
10-Carboxy-13-deoxycarminomycin <=> 13-Deoxycarminomycin + CO2
13-Deoxycarminomycin + S-Adenosyl-L-methionine <=> 13-Deoxydaunorubicin + S-Adenosyl-L-homocysteine
13-Deoxydaunorubicin + NADPH + H+ + Oxygen <=> 13-Dihydrodaunorubicin + NADP+ + H2O
13-Dihydrodaunorubicin + NADPH + H+ + Oxygen <=> Daunorubicin + NADP+ + 2 H2O
Daunorubicin + NADPH + H+ + Oxygen <=> Doxorubicin + NADP+ + H2O
13-Deoxycarminomycin + NADPH + H+ + Oxygen <=> 13-Dihydrocarminomycin + NADP+ + H2O
13-Dihydrocarminomycin + NADPH + H+ + Oxygen <=> Carminomycin + NADP+ + 2 H2O
Carminomycin + S-Adenosyl-L-methionine <=> Daunorubicin + S-Adenosyl-L-homocysteine
Daunorubicin <=> (13S)-13-Dihydrodaunorubicin
(S)-DNPA <=> 6-Deoxydihydrokalafungin
6-Deoxydihydrokalafungin + Oxygen <=> Dihydrokalafungin + H2O
2 DHKred-OH <=> Actinorhodin
Dihydrokalafungin <=> Medermycin
Tetracenomycin F2 <=> Tetracenomycin F1 + H2O
Tetracenomycin F1 + Oxygen <=> Tetracenomycin D3 + H2O
Tetracenomycin D3 <=> Tetracenomycin B3
Tetracenomycin B3 <=> Tetracenomycin E
Tetracenomycin E + S-Adenosyl-L-methionine <=> Tetracenomycin A2 + S-Adenosyl-L-homocysteine
Tetracenomycin F1 <=> Tetracenomycin F1 methylester
Tetracenomycin F1 <=> Decarboxytetracenomycin F1
Tetracenomycin D3 <=> Tetracenomycin D3 methylester
Tetracenomycin D3 <=> Tetracenomycin D1
Tetracenomycin B3 <=> Tetracenomycin B1
S-Adenosyl-L-methionine + Tetracenomycin B3 <=> S-Adenosyl-L-homocysteine + Tetracenomycin B2
Tetracenomycin A2 <=> Tetracenomycin X
4-Demethylpremithramycinone + S-Adenosyl-L-methionine <=> Premithramycinone + S-Adenosyl-L-homocysteine
Premithramycinone + dTDP-D-olivose <=> Premithramycin A1 + dTDP
Premithramycin A1 + dTDP-D-oliose <=> Premithramycin A2' + dTDP
Premithramycin A2' + dTDP-D-mycarose <=> Premithramycin A3' + dTDP
Premithramycin A3' + S-Adenosyl-L-methionine <=> Premithramycin A3 + S-Adenosyl-L-homocysteine
sym-Homospermidine <=> Trachelanthamidine
Trachelanthamidine <=> Retronecine
Retronecine + 2 L-Isoleucine <=> Senecionine
1-Methylpyrrolinium + Benzoate <=> Cocaine
Cocaine + H2O <=> Ecgonine methyl ester + Benzoate
Ecgonine methyl ester + H2O <=> Ecgonine + Methanol
Ecgonine <=> Pseudoecgonine
Pseudoecgonine + ATP + CoA <=> Pseudoecgonyl-CoA + AMP
4-(1-Methyl-2-pyrrolidinyl)-3-oxobutanoate <=> Hygrine
4-(1-Methyl-2-pyrrolidinyl)-3-oxobutanoate <=> Tropinone
Tropinone + NADPH + H+ <=> Pseudotropine + NADP+
Acetyl-CoA + Tropine <=> CoA + Acetyltropine
Acetyl-CoA + Pseudotropine <=> CoA + Acetylpseudotropine
Pseudotropine <=> Calystegin A3
Nicotine <=> Nornicotine
Cadaverine + H2O + Oxygen <=> 5-Aminopentanal + Ammonia + Hydrogen peroxide
5-Aminopentanal <=> Piperideine
Anabasine <=> Anatalline
L-Phenylalanine <=> Tropate
trans-Cinnamate <=> Cocaine
L-Proline + Peptidyl-carrier protein + ATP <=> L-Prolyl-[pcp] + AMP + Diphosphate
Pyrrole-2-carbonyl-[pcp] + Peptidyl-carrier protein <=> Pyrrole-2-carbonyl-[pcp] + Peptidyl-carrier protein
L-Tyrosine + Peptidyl-carrier protein + ATP <=> L-Tyrosyl-[pcp] + AMP + Diphosphate
L-Tyrosyl-[pcp] + Oxygen <=> beta-Hydroxy-L-tyrosyl-[pcp] + H2O
beta-Hydroxy-L-tyrosyl-[pcp] <=> beta-Keto-L-tyrosyl-[pcp]
3-(4-Hydroxyphenyl)pyruvate + Dimethylallyl diphosphate <=> 3-Dimethylallyl-4-hydroxyphenylpyruvate + Diphosphate
3-Dimethylallyl-4-hydroxyphenylpyruvate + Oxygen <=> 3-Dimethylallyl-4-hydroxymandelic acid + CO2
3-Dimethylallyl-4-hydroxymandelic acid + Oxygen <=> 3-Dimethylallyl-4-hydroxybenzoate + CO2 + H2O
beta-Hydroxy-L-tyrosyl-[pcp] <=> 3-Dimethylallyl-beta-hydroxy-L-tyrosyl-[pcp]
3-Dimethylallyl-beta-hydroxy-L-tyrosyl-[pcp] <=> 3-Dimethylallyl-4-hydroxybenzaldehyde
3-Dimethylallyl-4-hydroxyphenylpyruvate <=> 3-Dimethylallyl-4-hydroxybenzaldehyde
3-Dimethylallyl-4-hydroxybenzaldehyde <=> 3-Dimethylallyl-4-hydroxybenzoate
beta-Keto-L-tyrosyl-[pcp] <=> 2-Hydroxy-beta-keto-L-tyrosyl-[pcp]
2-Hydroxy-beta-keto-L-tyrosyl-[pcp] <=> 3-Amino-4,7-dihydroxycoumarin
3-Amino-4,7-dihydroxycoumarin <=> 3-Amino-4,7-dihydroxy-8-chlorocoumarin
Coumermycin D + 2 Pyrrole-2-carbonyl-[pcp] <=> Coumermycin A1
Novobiocic acid + dTDP-5-dimethyl-L-lyxose <=> Demethyldecarbamoylnovobiocin + dTDP
Demethyldecarbamoylnovobiocin + S-Adenosyl-L-methionine <=> Decarbamoylnovobiocin + S-Adenosyl-L-homocysteine
Decarbamoylnovobiocin + Carbamoyl phosphate <=> Novobiocin + Orthophosphate
Chlorobiocic acid + dTDP-5-dimethyl-L-lyxose <=> Novclobiocin 105 + dTDP
Novclobiocin 105 + S-Adenosyl-L-methionine <=> Novclobiocin 104 + S-Adenosyl-L-homocysteine
Novclobiocin 104 + Pyrrole-2-carbonyl-[pcp] <=> Clorobiocin
3-Amino-4,7-dihydroxy-8-chlorocoumarin + 3-Dimethylallyl-4-hydroxybenzoate <=> Chlorobiocic acid
3-Methylpyrrole-2,4-dicarboxylic acid + 3-Amino-4,7-dihydroxycoumarin + ATP <=> 5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + AMP + Diphosphate
5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + 3-Amino-4,7-dihydroxycoumarin + ATP + 2 S-Adenosyl-L-methionine <=> Coumermic acid + AMP + Diphosphate + 2 S-Adenosyl-L-homocysteine
Nicotinate + 3,6-Dihydropyridine <=> Anatabine + CO2
Phenylpropanoate <=> 3-(3-Hydroxyphenyl)propanoic acid
trans-Cinnamate <=> trans-3-Hydroxycinnamate
Phenylpropanoate + Oxygen + NADH + H+ <=> cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol + NAD+
trans-Cinnamate + Oxygen + NADH + H+ <=> cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+
cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol + NAD+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + NADH + H+
cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+ <=> trans-2,3-Dihydroxycinnamate + NADH + H+
3-(3-Hydroxyphenyl)propanoic acid + Oxygen + NADH + H+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + H2O + NAD+
trans-3-Hydroxycinnamate + Oxygen + NADH + H+ <=> trans-2,3-Dihydroxycinnamate + H2O + NAD+
trans-2,3-Dihydroxycinnamate + Oxygen <=> 2-Hydroxy-6-ketononatrienedioate
2-Hydroxy-6-ketononatrienedioate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Fumarate
Phenylacetic acid <=> 4-Hydroxyphenylacetate
Phenylacetic acid <=> 3-Hydroxyphenylacetate
Apigenin + 2 NADPH + 2 H+ + Oxygen <=> 2-Hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O
2-Hydroxy-2,3-dihydrogenistein <=> Genistein + H2O
Genistein + S-Adenosyl-L-methionine <=> Prunetin + S-Adenosyl-L-homocysteine
Biochanin A + UDP-glucose <=> Biochanin A-beta-D-glucoside + UDP
Biochanin A-beta-D-glucoside + Malonyl-CoA <=> Biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) + CoA
Isoquercitrin + Malonyl-CoA <=> Quercetin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-glucoside <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + Malonyl-CoA <=> 4'''-Demalonylsalvianin + CoA
4'''-Demalonylsalvianin + Malonyl-CoA <=> Salvianin + CoA
Pelargonidin 3-O-glucoside + Malonyl-CoA <=> Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-glucoside + UDP-L-rhamnose <=> Pelargonidin 3-O-rutinoside + UDP
Pelargonidin 3-O-rutinoside + UDP-glucose <=> Pelargonidin 3-O-rutinoside 5-O-beta-D-glucoside + UDP
Kaempferol 3-O-glucoside + UDP-glucose <=> Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP
Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-glucose <=> Kaempferol 3-sophorotrioside + UDP
Kaempferol 3-sophorotrioside + p-Coumaroyl-CoA <=> Kaempferol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] + CoA
Kaempferol + S-Adenosyl-L-methionine <=> Kaempferide + S-Adenosyl-L-homocysteine
Kaempferol + UDP-alpha-D-galactose <=> Kaempferol-3-O-galactoside + UDP
Quercetin 3,4'-bissulfate + 3'-Phosphoadenylyl sulfate <=> Quercetin 3,4',7-trissulfate + Adenosine 3',5'-bisphosphate
Quercetin + UDP-glucose <=> Quercimeritrin + UDP
Rutin + UDP-D-xylose <=> Quercetin 3-(2G-xylosylrutinoside) + UDP
Isoquercitrin + UDP-glucose <=> Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP
Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-glucose <=> Quercetin 3-sophorotrioside + UDP
Isoquercitrin + UDP-D-xylose <=> Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside] + UDP
Myricetin + S-Adenosyl-L-methionine <=> Laricitrin + S-Adenosyl-L-homocysteine
Laricitrin + S-Adenosyl-L-methionine <=> Syringetin + S-Adenosyl-L-homocysteine
Cyanidin 3-O-glucoside + Malonyl-CoA <=> Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA
Cyanidin 3-O-glucoside + UDP-L-rhamnose <=> Cyanidin 3-O-rutinoside + UDP
Cyanidin 3-O-rutinoside + UDP-glucose <=> Cyanidin 3-O-rutinoside 5-O-beta-D-glucoside + UDP
Naringenin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Naringin + UDP
Apigenin 7-O-beta-D-glucoside + Malonyl-CoA <=> Apigenin 7-(6''-malonylglucoside) + CoA
Apigenin <=> Vitexin
Vitexin <=> Vitexin 2''-O-beta-L-rhamnoside
Vitexin 2''-O-beta-L-rhamnoside + S-Adenosyl-L-methionine <=> Isoswertisin 2''-rhamnoside + S-Adenosyl-L-homocysteine
Apigenin <=> Isovitexin
Apigenin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Apigenin 7-O-neohesperidoside + UDP
Luteolin 7-O-glucuronide + UDP-glucuronate <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + UDP
Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + UDP-glucuronate <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + UDP
Luteolin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Scolymoside + UDP
2-Aminomalonate semialdehyde <=> Aminoacetaldehyde + CO2
1,2,4-Trichlorobenzene + NADH + H+ + Oxygen <=> 3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3,4,6-Trichlorocatechol + NADH + H+
3,4,6-Trichlorocatechol + Oxygen <=> 2,3,5-Trichloro-cis,cis-muconate
2,3,5-Trichloro-cis,cis-muconate <=> 2,5-Dichloro-carboxymethylenebut-2-en-4-olide + Hydrochloric acid
2,5-Dichloro-carboxymethylenebut-2-en-4-olide + H2O <=> 2,5-Dichloro-4-oxohex-2-enedioate
D-Ribose 1,5-bisphosphate + ATP <=> 5-Phospho-alpha-D-ribose 1-diphosphate + ADP
alpha-D-Ribose 1-phosphate <=> D-Ribose 1,5-bisphosphate
trans-4-Carboxymethylenebut-2-en-4-olide + H2O <=> 2-Maleylacetate
3-Chlorocatechol + Oxygen <=> 2-Chloro-cis,cis-muconate
2-Chloro-cis,cis-muconate <=> trans-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid
Quinate + NADP+ <=> 3-Dehydroquinate + NADPH + H+
Shikimate + NAD+ <=> 3-Dehydroshikimate + NADH + H+
2,5-Dichloro-4-oxohex-2-enedioate + 2 NADH + 2 H+ <=> 2-Chloro-3-oxoadipate + Hydrochloric acid + 2 NAD+
1,2,4-Trichlorobenzene <=> 1,4-Dichlorobenzene
1,4-Dichlorobenzene <=> Chlorobenzene
Hydroquinone + NADPH + H+ + Oxygen <=> Benzene-1,2,4-triol + NADP+ + H2O
4-Hydroxyaniline + H2O <=> p-Benzoquinone + Ammonia
Benzene-1,2,4-triol <=> 2-Hydroxy-1,4-benzoquinone
2-Hydroxy-1,4-benzoquinone <=> p-Benzoquinone + H2O
2-Chloro-3-oxoadipate <=> Chloroacetic acid + Succinate
Chlorobenzene + Oxygen + NADH + H+ <=> 3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3-Chlorocatechol + NADH + H+
D-Xylulose 5-phosphate + Thiamin diphosphate <=> alpha,beta-Dihydroxyethyl-TPP + D-Glyceraldehyde 3-phosphate
alpha,beta-Dihydroxyethyl-TPP + Formaldehyde <=> Thiamin diphosphate + Glycerone
Sedoheptulose 7-phosphate + Thiamin diphosphate <=> alpha,beta-Dihydroxyethyl-TPP + D-Ribose 5-phosphate
3-Hexaprenyl-4-hydroxybenzoate + Oxygen <=> 3-Hexaprenyl-4,5-dihydroxybenzoate + H2O
3-Hexaprenyl-4-hydroxy-5-methoxybenzoate <=> 2-Hexaprenyl-6-methoxyphenol + CO2
UDP-6-sulfoquinovose + 1,2-Diacyl-sn-glycerol <=> Sulfoquinovosyldiacylglycerol + UDP
S-Adenosyl-L-methionine + N-Methylethanolamine phosphate <=> S-Adenosyl-L-homocysteine + Phosphodimethylethanolamine
S-Adenosyl-L-methionine + Phosphodimethylethanolamine <=> S-Adenosyl-L-homocysteine + Choline phosphate
Ethanolamine phosphate + H2O <=> Ethanolamine + Orthophosphate
Choline phosphate + H2O <=> Choline + Orthophosphate
sn-Glycerol 3-phosphate + Acyl-CoA <=> 2-Acyl-sn-glycerol 3-phosphate + CoA
1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 4-phosphate + Orthophosphate
Tetrabromobisphenol A <=> Tribromobisphenol A + Hydrobromic acid
Tribromobisphenol A <=> Dibromobisphenol A + Hydrobromic acid
Dibromobisphenol A <=> Monobromobisphenol A + Hydrobromic acid
Monobromobisphenol A <=> Bisphenol A + Hydrobromic acid
2 Bisphenol A <=> 4-Methyl-2,4-bis-(p-hydroxyphenyl)pent-1-ene
Bisphenol A <=> 5-Hydroxybisphenol A
5-Hydroxybisphenol A <=> 4,5-Bisphenol-o-quinone
Bisphenol A + NADH + H+ + Oxygen <=> 1,2-Bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O
Bisphenol A + NADH + H+ + Oxygen <=> 2,2-Bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O
1,2-Bis(4-hydroxyphenyl)-2-propanol <=> 4,4'-Dihydroxy-alpha-methylstilbene + H2O
4,4'-Dihydroxy-alpha-methylstilbene + Oxygen <=> 4-Hydroxybenzaldehyde + 4'-Hydroxyacetophenone
2,2-Bis(4-hydroxyphenyl)-1-propanol <=> 2,2-Bis(4-hydroxyphenyl)-propanoic acid
2,2-Bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + Oxygen <=> 2,3-Bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O
2,3-Bis(4-hydroxyphenyl)-1,2-propanediol <=> 4-Hydroxyphenacyl alcohol + 4-Hydroxybenzoate
4-Ethylphenol + NADPH + H+ + Oxygen <=> 1-(4'-Hydroxyphenyl)ethanol + NADP+ + H2O
1-(4'-Hydroxyphenyl)ethanol + NAD+ <=> 4'-Hydroxyacetophenone + NADH + H+
4'-Hydroxyacetophenone + NADPH + H+ + Oxygen <=> 4-Hydroxyphenyl acetate + NADP+ + H2O
4-Hydroxyphenyl acetate + H2O <=> Hydroquinone + Acetate
UDP-N-acetyl-D-galactosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-D-galactosaminuronic acid + 2 NADH + 2 H+
Coproporphyrinogen III + 2 S-Adenosyl-L-methionine <=> Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine
Divinylprotochlorophyllide + NADPH + H+ <=> Protochlorophyllide + NADP+
2-Hydroxyhepta-2,4-dienedioate + H2O <=> 2,4-Dihydroxyhept-2-enedioate
2-Naphthoic acid <=> 5,6,7,8-Tetrahydro-2-naphthoic acid
5,6,7,8-Tetrahydro-2-naphthoic acid <=> Decahydro-2-naphthoic acid
5,6,7,8-Tetrahydro-2-naphthoic acid <=> cis-2-Carboxycyclohexyl-acetic acid
Tetralin <=> 5,6,7,8-Tetrahydro-2-naphthoic acid
2-Naphthoic acid + FADH2 + Oxygen <=> 1-Hydroxy-2-naphthoate + FAD + H2O
2-Methylnaphthalene + Fumarate <=> 2-Naphtylmethylsuccinic acid
2-Naphtylmethylsuccinic acid + Succinyl-CoA <=> Naphthyl-2-methyl-succinyl-CoA + Succinate
Naphthyl-2-methyl-succinyl-CoA <=> Naphthyl-2-methylene-succinyl-CoA + 2 H+
Naphthyl-2-methylene-succinyl-CoA + H2O <=> Naphthyl-2-hydroxymethyl-succinyl CoA
Naphthyl-2-hydroxymethyl-succinyl CoA <=> Naphthyl-2-oxomethyl-succinyl-CoA + 2 H+
Naphthyl-2-oxomethyl-succinyl-CoA + CoA <=> 2-Naphthoyl-CoA + Succinyl-CoA
1-Methylnaphthalene + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene + NAD+
cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene + NAD+ <=> 1,2-Dihydroxy-8-methylnaphthalene + NADH + H+
1,2-Dihydroxy-8-methylnaphthalene + Oxygen <=> 2-Hydroxy-8-methylchromene-2-carboxylate
2-Hydroxy-8-methylchromene-2-carboxylate <=> 2-Hydroxy-3-methylbenzalpyruvate
2-Hydroxy-3-methylbenzalpyruvate + H2O <=> 3-Methylsalicylaldehyde + Pyruvate
3-Methylsalicylaldehyde + NAD+ + H2O <=> 3-Methylsalicylate + NADH + H+
3-Methylsalicylate + Oxygen + NADH + H+ <=> 2,3-Dihydroxytoluene + NAD+ + CO2 + H2O
1-Methylnaphthalene + Oxygen + NADH + H+ <=> 1-Hydroxymethylnaphthalene + NAD+ + H2O
1-Hydroxymethylnaphthalene + NAD+ <=> 1-Naphthaldehyde + NADH + H+
1-Naphthaldehyde + NAD+ + H2O <=> 1-Naphthoic acid + NADH + H+
1-Naphthoic acid + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+
cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene <=> 1,2-Dihydroxy-8-carboxynaphthalene
1,2-Dihydroxy-8-carboxynaphthalene + Oxygen <=> 2-Carboxy-2-hydroxy-8-carboxychromene
2-Carboxy-2-hydroxy-8-carboxychromene <=> 2-Hydroxy-3-carboxybenzalpyruvate
2-Hydroxy-3-carboxybenzalpyruvate + H2O <=> 3-Formylsalicylic acid + Pyruvate
3-Formylsalicylic acid + Oxygen + H2O <=> 2-Hydroxyisophthalic acid + Hydrogen peroxide
2-Hydroxyisophthalic acid <=> Salicylate + CO2
2-Methylnaphthalene + Oxygen + NADH + H+ <=> (2-Naphthyl)methanol + NAD+ + H2O
(2-Naphthyl)methanol + NAD+ <=> 2-Naphthaldehyde + NADH + H+
2-Naphthaldehyde + NAD+ + H2O <=> 2-Naphthoic acid + NADH + H+
2-Naphthaldehyde <=> 4-Formylsalicylic acid
(2-Naphthyl)methanol + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene + NAD+
cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene + NAD+ <=> 1,2-Dihydroxy-7-hydroxymethylnaphthalene + NADH + H+
1,2-Dihydroxy-7-hydroxymethylnaphthalene + Oxygen <=> 2-Hydroxy-7-hydroxymethylchromene-2-carboxylate
2-Hydroxy-7-hydroxymethylchromene-2-carboxylate <=> 2-Hydroxy-4-hydroxymethylbenzalpyruvate
2-Hydroxy-4-hydroxymethylbenzalpyruvate + H2O <=> 4-Hydroxymethylsalicylaldehyde + Pyruvate
4-Hydroxymethylsalicylaldehyde + NAD+ + H2O <=> 4-Hydroxymethylsalicylate + NADH + H+
4-Hydroxymethylsalicylate + Oxygen + NADH + H+ <=> 4-Hydroxymethylcatechol + NAD+ + H2O + CO2
2-Methylnaphthalene + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene + NAD+
cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene <=> 4-Methylsalicylate
4-Methylsalicylate + Oxygen + NADH + H+ <=> 4-Methylcatechol + NAD+ + H2O + CO2
N-Cyclohexylformamide + H2O <=> Cyclohexylamine + Formate
(3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+
5-Carboxy-2-pentenoyl-CoA + H2O <=> (3S)-3-Hydroxyadipyl-CoA
Adipyl-CoA + FAD <=> 5-Carboxy-2-pentenoyl-CoA + FADH2
Adipate + CoA + ATP <=> Adipyl-CoA + AMP + Diphosphate
Cyclohexane + Oxygen + NADH + H+ <=> Cyclohexanol + NAD+ + H2O
Violaxanthin <=> Neoxanthin
Neoxanthin <=> 9'-cis-Neoxanthin
Violaxanthin <=> 9-cis-Violaxanthin
9-cis-Violaxanthin <=> 9'-cis-Neoxanthin
9'-cis-Neoxanthin + Oxygen <=> Xanthoxin + C25-Allenic-apo-aldehyde
9-cis-Violaxanthin + Oxygen <=> Xanthoxin + C25-Epoxy-apo-aldehyde
Xanthoxin + NAD+ <=> Abscisic aldehyde + NADH + H+
Xanthoxin <=> Xanthoxic acid
Xanthoxic acid <=> Abscisate
Abscisic aldehyde + H2O + Oxygen <=> Abscisate + Hydrogen peroxide
Abscisic aldehyde <=> Abscisic alcohol
Abscisic alcohol <=> Abscisate
all-trans-Neurosporene <=> alpha-Zeacarotene
alpha-Zeacarotene <=> delta-Carotene
delta-Carotene <=> alpha-Carotene
Lycopene <=> delta-Carotene
alpha-Carotene <=> Lutein
2-Chloro-4-hydroxy-6-amino-1,3,5-triazine + H2O <=> Ammelide + Hydrochloric acid
Ammelide + H2O <=> Cyanuric acid + Ammonia
Melamine + H2O <=> Ammeline + Ammonia
Ammeline + H2O <=> Ammelide + Ammonia
Cyromazine + H2O <=> N-Cyclopropylammeline + Ammonia
N-Cyclopropylammeline + H2O <=> N-Cyclopropylammelide + Ammonia
N-Cyclopropylammelide + H2O <=> Cyanuric acid + Cyclopropylamine
3-Oxopropanoate <=> Acetaldehyde + CO2
Formate + ATP + 5'-Phosphoribosylglycinamide <=> ADP + Orthophosphate + 5'-Phosphoribosyl-N-formylglycinamide
Formate + ATP + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
ATP + Lombricine <=> ADP + N-Phospholombricine
L-Glutamate + L-Aspartate 4-semialdehyde <=> 2-Oxoglutarate + L-2,4-Diaminobutanoate
L-2,4-Diaminobutanoate + Acetyl-CoA <=> N(gamma)-Acetyldiaminobutyrate + CoA
N(gamma)-Acetyldiaminobutyrate <=> H2O + Ectoine
Sulfoacetaldehyde + NAD+ + H2O <=> Sulfoacetate + NADH + H+
Glutathione + Formaldehyde <=> S-(Hydroxymethyl)glutathione
S-(Hydroxymethyl)glutathione + NAD+ <=> S-Formylglutathione + NADH + H+
trans-Hex-2-enoyl-CoA + NADPH + H+ <=> Hexanoyl-CoA + NADP+
2-Oxobutanoate + CoA <=> Propanoyl-CoA + Formate
3-Hydroxyaminophenol <=> Aminohydroquinone
cis,cis-Muconate <=> (S)-5-Oxo-2,5-dihydrofuran-2-acetate
(S)-5-Oxo-2,5-dihydrofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate
34a-Deoxy-rifamycin W <=> Rifamycin W
Rifamycin W <=> Rifamycin W-hemiacetal
Rifamycin W <=> Rifamycin Z
Rifamycin W-hemiacetal <=> Demethyl-desacetyl-rifamycin S
Rifamycin Z <=> Demethyl-desacetyl-rifamycin S
Demethyl-desacetyl-rifamycin S <=> 27-O-Demethyl-25-O-desacetylrifamycin SV
Acetyl-CoA + 27-O-Demethyl-25-O-desacetylrifamycin SV <=> CoA + 27-O-Demethylrifamycin SV
S-Adenosyl-L-methionine + 27-O-Demethylrifamycin SV <=> S-Adenosyl-L-homocysteine + Rifamycin
Rifamycin <=> Rifamycin S
Naphthalene + NADPH + Oxygen + H+ <=> (1R,2S)-Naphthalene 1,2-oxide + NADP+ + H2O
Naphthalene + NADPH + Oxygen + H+ <=> (1S,2R)-Naphthalene 1,2-oxide + NADP+ + H2O
(1R,2S)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene
(1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene
(1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene
(1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene <=> (1R)-Hydroxy-(2R)-N-acetyl-L-cysteinyl-1,2-dihydronaphthalene
(1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene <=> (1R)-N-Acetyl-L-cysteinyl-(2R)-hydroxy-1,2-dihydronaphthalene
(1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene <=> (1R,2R)-3-[(1,2-Dihydro-2-hydroxy-1-naphthalenyl)thio]-2-oxopropanoic acid
(1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene <=> (1S)-Hydroxy-(2S)-N-acetyl-L-cysteinyl-1,2-dihydronaphthalene
(1R,2S)-Naphthalene 1,2-oxide <=> 1-Naphthol
(1S,2R)-Naphthalene 1,2-oxide <=> 1-Naphthol
(1R,2S)-Naphthalene 1,2-oxide <=> 2-Naphthol
(1S,2R)-Naphthalene 1,2-oxide <=> 2-Naphthol
(1R,2S)-Naphthalene 1,2-oxide + H2O <=> 1,2-Dihydronaphthalene-1,2-diol
(1S,2R)-Naphthalene 1,2-oxide + H2O <=> 1,2-Dihydronaphthalene-1,2-diol
1,2-Dihydronaphthalene-1,2-diol + NADP+ <=> Naphthalene-1,2-diol + NADPH + H+
1,2-Dihydronaphthalene-1,2-diol + NADPH + Oxygen + H+ <=> 1,2-Dihydroxy-3,4-epoxy-1,2,3,4-tetrahydronaphthalene + NADP+ + H2O
Naphthalene-1,2-diol <=> 1,2-Naphthoquinone
1-Naphthol <=> 1,4-Dihydroxynaphthalene
1,4-Dihydroxynaphthalene <=> 1,4-Naphthoquinone
2-Naphthol + NADPH + Oxygen + H+ <=> Naphthalene-1,2-diol + NADP+ + H2O
1-Nitronaphthalene + NADPH + Oxygen + H+ <=> 1-Nitronaphthalene-7,8-oxide + NADP+ + H2O
1-Nitronaphthalene + NADPH + Oxygen + H+ <=> 1-Nitronaphthalene-5,6-oxide + NADP+ + H2O
1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
1-Nitronaphthalene-5,6-oxide + H2O <=> 1-Nitro-5,6-dihydroxy-dihydronaphthalene
1-Nitronaphthalene <=> 1-Nitrosonaphthalene
1-Nitrosonaphthalene <=> N-Hydroxy-1-aminonaphthalene
N-Hydroxy-1-aminonaphthalene <=> 1-Naphthylamine
5,6-Epoxytetraene + H2O <=> Lipoxin A4
5,6-Epoxytetraene + H2O <=> Lipoxin B4
2 Glutathione + 5(S)-HPETE <=> Glutathione disulfide + 5(S)-HETE + H2O
2 Glutathione + 15(S)-HPETE <=> Glutathione disulfide + (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + H2O
Hepoxilin A3 + H2O <=> Trioxilin A3
Hepoxilin B3 + H2O <=> Trioxilin B3
Arachidonate + Oxygen <=> 12(R)-HPETE
12(S)-HPETE <=> Hepoxilin A3
12(S)-HPETE <=> Hepoxilin B3
15(S)-HPETE <=> 15H-11,12-EETA
15(S)-HPETE <=> 11H-14,15-EETA
15H-11,12-EETA + H2O <=> 11,12,15-THETA
11H-14,15-EETA + H2O <=> 11,14,15-THETA
Arachidonate + Oxygen <=> 11(R)-HPETE
Arachidonate + Oxygen + NADPH + H+ <=> 14,15-EET + NADP+ + H2O
Arachidonate + Oxygen <=> 9(S)-HPETE
Arachidonate + Oxygen + NADPH + H+ <=> 11,12-EET + NADP+ + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 8,9-EET + NADP+ + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 5,6-EET + NADP+ + H2O
Arachidonate + Oxygen <=> 8(S)-HPETE
Arachidonate + Oxygen + NADPH + H+ <=> 16(R)-HETE + NADP+ + H2O
Linoleate + Oxygen + NADPH + H+ <=> 9(10)-EpOME + NADP+ + H2O
Linoleate + Oxygen + NADPH + H+ <=> 12(13)-EpOME + NADP+ + H2O
Linoleate + Oxygen <=> 9(S)-HPODE
13(S)-HODE + NAD+ <=> 13-OxoODE + NADH + H+
GDP-4-dehydro-6-deoxy-D-mannose <=> GDP-4-keto-6-L-deoxygalactose
GDP-4-keto-6-L-deoxygalactose + NADPH + H+ <=> GDP-L-fucose + NADP+
Linoleate + Oxygen <=> 8(R)-HPODE
8(R)-HPODE <=> (7S,8S)-DiHODE
Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate
Bromobenzene + NADPH + Oxygen + H+ <=> Bromobenzene-3,4-oxide + NADP+ + H2O
Delta-12-Prostaglandin J2 <=> 15-Deoxy-Delta12,14-PGJ2 + H2O
Bromobenzene + NADPH + Oxygen + H+ <=> Bromobenzene-2,3-oxide + NADP+ + H2O
Bromobenzene-3,4-oxide + Glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene
Bromobenzene-2,3-oxide + Glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene
Bromobenzene-3,4-oxide + H2O <=> Bromobenzene-3,4-dihydrodiol
Bromobenzene-2,3-oxide + H2O <=> Bromobenzene-2,3-dihydrodiol
Bromobenzene-3,4-oxide <=> 4-Bromophenol
Bromobenzene-2,3-oxide <=> 2-Bromophenol
4-Bromophenol + NADPH + Oxygen + H+ <=> 4-Bromophenol-2,3-epoxide + NADP+ + H2O
4-Bromophenol-2,3-epoxide <=> 4-Bromocatechol
4-Bromocatechol <=> 4-Bromo-3,5-cyclohexadiene-1,2-dione
Bromobenzene-3,4-dihydrodiol <=> 4-Bromocatechol
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-9,10-oxide + NADP+ + H2O
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-7,8-oxide + NADP+ + H2O
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-4,5-oxide + NADP+ + H2O
Benzo[a]pyrene-7,8-oxide + H2O <=> Benzo[a]pyrene-7,8-dihydrodiol
Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene
Benzo[a]pyrene-7,8-dihydrodiol + Glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O
Benzo[a]pyrene-7,8-dihydrodiol + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide + NADP+ + H2O
Benzo[a]pyrene-9,10-oxide <=> 9-Hydroxybenzo[a]pyrene
9-Hydroxybenzo[a]pyrene + NADPH + Oxygen + H+ <=> 9-Hydroxybenzo[a]pyrene-4,5-oxide + NADP+ + H2O
1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> 2,2-Dichloroacetaldehyde + NADP+ + H2O
1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> 1,1-Dichloroethylene epoxide + NADP+ + H2O
1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> Chloroacetyl chloride + NADP+ + H2O
2,2-Dichloroacetaldehyde + Glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl glutathione
1,1-Dichloroethylene epoxide + Glutathione <=> 2-(S-Glutathionyl)acetyl chloride + Hydrochloric acid
Chloroacetyl chloride + Glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric acid
2-(S-Glutathionyl)acetyl chloride + Glutathione <=> 2-(S-Glutathionyl)acetyl glutathione + Hydrochloric acid
2,2-Dichloroacetaldehyde + H2O <=> 2,2-Dichloro-1,1-ethanediol
Chloroacetyl chloride + H2O <=> Chloroacetic acid
2-(S-Glutathionyl)acetyl chloride + H2O <=> 2-S-Glutathionyl acetate
Trichloroethene + NADPH + Oxygen + H+ <=> TCE epoxide + NADP+ + H2O
Trichloroethene + NADPH + Oxygen + H+ <=> Chloral + NADP+ + H2O
Trichloroethene + Glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric acid
Chloral + H2O <=> Chloral hydrate
TCE epoxide <=> Dichloroacetyl chloride
Dichloroacetyl chloride <=> Dichloroacetate
Chloral hydrate + NAD+ <=> Trichloroacetate + NADH + H+
Chloral hydrate + NADH + H+ <=> Trichloroethanol + NAD+ + H2O
Trichloroethanol + UDP-glucuronate <=> Trichloroethanol glucuronide + UDP
14,15-EET + H2O <=> 14,15-DHET
11,12-EET + H2O <=> 11,12-DHET
8,9-EET + H2O <=> 8,9-DHET
5,6-EET + H2O <=> 5,6-DHET
1,2-Dibromoethane + NADPH + Oxygen + H+ <=> 2-Bromoacetaldehyde + NADP+ + H2O + Hydrobromic acid
1,2-Dibromoethane + Glutathione + H+ <=> Glutathione episulfonium ion + 2 Hydrobromic acid
S-(Formylmethyl)glutathione <=> Thiodiacetic acid
S-(Formylmethyl)glutathione <=> Thiodiacetic acid sulfoxide
2-Bromoacetaldehyde + Glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic acid
Glutathione episulfonium ion + H2O <=> S-(2-Hydroxyethyl)glutathione
S-(2-Hydroxyethyl)glutathione <=> S-(2-Hydroxyethyl)-N-acetyl-L-cysteine
Glutathione episulfonium ion <=> S-[2-(N7-Guanyl)ethyl]-N-acetyl-L-cysteine
S-(Formylmethyl)glutathione <=> S-(2-Hydroxyethyl)glutathione
12(13)-EpOME + H2O <=> 12,13-DHOME
9(10)-EpOME + H2O <=> 9,10-DHOME
Trichloroacetate <=> Dichloroacetate
2-(S-Glutathionyl)acetyl glutathione + H2O <=> 2-S-Glutathionyl acetate + Glutathione
3-Dehydro-L-gulonate 6-phosphate + H+ <=> L-Xylulose 5-phosphate + CO2
3-Dehydro-L-gulonate + ATP <=> 3-Dehydro-L-gulonate 6-phosphate + ADP
Sorbitol 6-phosphate + NAD+ <=> D-Fructose 6-phosphate + NADH + H+
D-Arabitol + NAD+ <=> D-Ribulose + NADH + H+
Mannitol + NAD+ <=> D-Mannose + NADH + H+
(2R)-3-Sulfolactate + NAD+ <=> 3-Sulfopyruvate + NADH + H+
(2R)-3-Sulfolactate + NADP+ <=> 3-Sulfopyruvate + NADPH + H+
Isopregnanolone + NADP+ <=> 5alpha-Pregnane-3,20-dione + NADPH + H+
S-(Hydroxymethyl)glutathione + NADP+ <=> S-Formylglutathione + NADPH + H+
2'-Deoxymugineic acid + NAD+ <=> 3''-Deamino-3''-oxonicotianamine + NADH + H+
2'-Deoxymugineic acid + NADP+ <=> 3''-Deamino-3''-oxonicotianamine + NADPH + H+
D-Arabitol + NADP+ <=> D-Xylulose + NADPH + H+
D-Arabitol + NADP+ <=> D-Ribulose + NADPH + H+
L-Iditol + NAD+ <=> L-Sorbose + NADH + H+
cis-4-Hydroxy-L-proline + NAD+ <=> 4-Oxoproline + NADH + H+
D-Glucose + NADP+ <=> D-Glucono-1,5-lactone + NADPH + H+
D-threo-Aldose + NAD+ <=> D-threo-Aldono-1,5-lactone + NADH + H+
3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADP+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH + H+
L-2-Hydroxyphytanate + Oxygen <=> 2-Oxophytanate + Hydrogen peroxide
Xylitol + Oxygen <=> D-Xylose + Hydrogen peroxide
Fluoroacetaldehyde + NAD+ + H2O <=> Fluoroacetate + NADH + H+
Acyl-CoA + NADP+ <=> trans-2,3-Dehydroacyl-CoA + NADPH + H+
L-Aspartate + H2O + NAD+ <=> Oxaloacetate + Ammonia + NADH + H+
L-Aspartate + H2O + NADP+ <=> Oxaloacetate + Ammonia + NADPH + H+
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
(R)-Canadine + 2 NADP+ <=> Berberine + 2 NADPH + 2 H+
(R)-6-Hydroxynicotine + H2O + Oxygen <=> 6-Hydroxypseudooxynicotine + Hydrogen peroxide
NADH + H+ + Oxygen <=> NAD+ + Hydrogen peroxide
NADPH + H+ + Oxygen <=> NADP+ + Hydrogen peroxide
AMP + Sulfite + Thioredoxin disulfide <=> Adenylyl sulfate + Thioredoxin
2 Thiosulfate + Decylubiquinone <=> Tetrathionate + Decylubiquinol
Violaxanthin + Ascorbate <=> Antheraxanthin + Dehydroascorbate + H2O
Antheraxanthin + Ascorbate <=> Zeaxanthin + Dehydroascorbate + H2O
Hydrogen + NADP+ <=> NADPH + H+
Pentane-2,4-dione + Oxygen <=> Acetate + Methylglyoxal
Gibberellin A44 + 2-Oxoglutarate + Oxygen <=> Gibberellin A19 + Succinate + CO2
2'-Deoxymugineic acid + 2-Oxoglutarate + Oxygen <=> Mugineic acid + Succinate + CO2
Mugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxymugineic acid + Succinate + CO2
2'-Deoxymugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxy-2'-deoxymugineic acid + Succinate + CO2
Benzoate + NADH + H+ + Oxygen <=> 1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
N,N-Dihydroxy-L-tyrosine <=> (E)-4-Hydroxyphenylacetaldehyde oxime + CO2 + H2O
2,3,5,6-Tetrachlorophenol + NADPH + H+ + Oxygen <=> Tetrachlorohydroquinone + NADP+ + H2O
Propylene + NADH + H+ + Oxygen <=> 1,2-Epoxypropane + NAD+ + H2O
Phenylacetone + NADPH + H+ + Oxygen <=> Benzyl acetate + NADP+ + H2O
Alkanesulfonate + Reduced FMN + Oxygen <=> Aldehyde + FMN + Sulfite + H2O
L-Phenylalanine + Tetrahydrobiopterin + Oxygen <=> L-Tyrosine + 4a-Hydroxytetrahydrobiopterin
L-Tyrosine + Tetrahydrobiopterin + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin
L-Tryptophan + Tetrahydrobiopterin + Oxygen <=> 5-Hydroxy-L-tryptophan + 4a-Hydroxytetrahydrobiopterin
1-Aminocyclopropane-1-carboxylate + Ascorbate + Oxygen <=> Ethylene + Cyanide ion + Dehydroascorbate + CO2 + 2 H2O
Deoxycholic acid + FAD + H2O <=> Cholic acid + FADH2
6-Hydroxynicotinate + H2O + Oxygen <=> 2,6-Dihydroxynicotinate + Hydrogen peroxide
Naringenin chalcone + Oxygen <=> Aureusidin + H2O
2 Eriodictyol chalcone + Oxygen <=> 2 Aureusidin + 2 H2O
Acetyl phosphate + Ammonia + Thioredoxin disulfide + H2O <=> Glycine + Orthophosphate + Thioredoxin
Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O <=> Sarcosine + Orthophosphate + Thioredoxin
Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O <=> Betaine + Orthophosphate + Thioredoxin
S-Adenosyl-L-methionine + Adenine in rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N6-methyladenine
S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N1-methylguanine
S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N2-methylguanine
S-Adenosyl-L-methionine + gamma-Tocopherol <=> S-Adenosyl-L-homocysteine + alpha-Tocopherol
S-Adenosyl-L-methionine + Uroporphyrinogen III <=> S-Adenosyl-L-homocysteine + Precorrin 1
S-Adenosyl-L-methionine + Precorrin 1 <=> S-Adenosyl-L-homocysteine + Precorrin 2
S-Adenosyl-L-methionine + [Cytochrome c]-arginine <=> S-Adenosyl-L-homocysteine + [Cytochrome c]-N(omega)-methylarginine
S-Adenosyl-L-methionine + Isoeugenol <=> S-Adenosyl-L-homocysteine + Methylisoeugenol
S-Adenosyl-L-methionine + Isoliquiritigenin <=> S-Adenosyl-L-homocysteine + 2'-O-Methylisoliquiritigenin
S-Adenosyl-L-methionine + Sarcosine <=> S-Adenosyl-L-homocysteine + N,N-Dimethylglycine
S-Adenosyl-L-methionine + N,N-Dimethylglycine <=> S-Adenosyl-L-homocysteine + Betaine
Carbamoyl phosphate + N-Acetylornithine <=> Orthophosphate + N-Acetyl-L-citrulline
L-Threonine + Fluoroacetaldehyde <=> Acetaldehyde + 4-Fluoro-L-threonine
2 alpha,alpha'-Trehalose 6-mycolate <=> alpha,alpha-Trehalose + alpha,alpha'-Trehalose 6,6'-bismycolate
Acetyl-CoA + alpha-2,8-Linked polymer of sialic acid <=> CoA + Polysialic acid acetylated at O-9
Acetyl-CoA + 10-Desacetyltaxuyunnanin C <=> CoA + Taxuyunnanin C
Malonyl-CoA + Anthocyanidin 3-O-beta-D-glucoside <=> CoA + Anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside)
NDP-glucose + D-Fructose <=> NDP + Sucrose
GDP-mannose + di-trans,poly-cis-Undecaprenyl phosphate <=> GDP + D-Mannosyl-1-phosphoundecaprenol
UDP-N-acetyl-alpha-D-glucosamine + 6-(alpha-D-Mannosyl)-beta-D-mannosyl-R <=> UDP + 6-(2-[N-Acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Mannosyl-R <=> UDP + 4-(N-Acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R
UDP-glucose + cis-Zeatin <=> UDP + O-beta-D-Glucopyranosyl-cis-zeatin
NDP-glucose + Amylose <=> NDP + Amylose
1,4-Dihydroxy-2-naphthoyl-CoA + H2O <=> 1,4-Dihydroxy-2-naphthoate + CoA
2-Succinylbenzoyl-CoA <=> 1,4-Dihydroxy-2-naphthoyl-CoA + H2O
2-alpha-D-Glucosyl-D-glucose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate
alpha,alpha-Trehalose + Orthophosphate <=> alpha-D-Glucose + D-Glucose 1-phosphate
UDP-glucose + Anthocyanin <=> UDP + Anthocyanin 3'-O-beta-D-glucoside
all-trans-Octaprenyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + all-trans-Nonaprenyl diphosphate
ATP + Cobinamide <=> Triphosphate + Adenosyl cobinamide
di-trans,poly-cis-Decaprenyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + di-trans,poly-cis-Undecaprenyl diphosphate
Prephytoene diphosphate <=> all-trans-Phytoene + Diphosphate
Dimethylallyl diphosphate + 3,6,9-Trihydroxypterocarpan <=> Diphosphate + Glyceocarpin
Dimethylallyl diphosphate + 3,6,9-Trihydroxypterocarpan <=> Diphosphate + 4-Glyceollidin
all-trans-Nonaprenyl diphosphate + 4-Hydroxybenzoate <=> Diphosphate + 3-Nonaprenyl-4-hydroxybenzoate
O-Phospho-L-serine + Hydrogen sulfide <=> L-Cysteine + Orthophosphate
alpha,omega-Diamine + 2-Oxoglutarate <=> omega-Aminoaldehyde + L-Glutamate
L-Arogenate + 2-Oxoglutarate <=> Prephenate + L-Glutamate
Nicotianamine + 2-Oxoglutarate <=> 3''-Deamino-3''-oxonicotianamine + L-Glutamate
dGTP + Depurinated DNA <=> Deoxyribose triphosphate + DNA containing guanine
ATP + myo-Inositol <=> ADP + 1D-myo-Inositol 3-phosphate
5-Amino-6-(5'-phospho-D-ribitylamino)uracil + H2O <=> 5-Amino-6-(1-D-ribitylamino)uracil + Orthophosphate
D-Ribulose 5-phosphate <=> L-3,4-Dihydroxybutan-2-one 4-phosphate + Formate
RNA + Orthophosphate <=> RNA + NDP
tRNA + Orthophosphate <=> tRNA + NDP
3'-Phosphoadenylyl sulfate + Glycolithocholate <=> Adenosine 3',5'-bisphosphate + Sulfoglycolithocholate
3'-Phosphoadenylyl sulfate + Dermatan <=> Adenosine 3',5'-bisphosphate + Dermatan 6'-sulfate
3'-Phosphoadenylyl sulfate + Glycochenodeoxycholate <=> Adenosine 3',5'-bisphosphate + Glycochenodeoxycholate 7-sulfate
Formyl-CoA + Oxalate <=> Formate + Oxalyl-CoA
1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Carboxylate
1-Acylglycerol + H2O <=> Glycerol + Carboxylate
Phenylglyoxylyl-CoA + H2O <=> alpha-Oxo-benzeneacetic acid + CoA
Deoxycholoyl-CoA + Cholic acid <=> Deoxycholic acid + Choloyl-CoA
Choloyl-CoA + H2O <=> Cholic acid + CoA
5'-Ribonucleotide + H2O <=> Ribonucleoside + Orthophosphate
sn-Glycerol 1-phosphate + H2O <=> Glycerol + Orthophosphate
1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3-phosphate + Orthophosphate
N8-Acetylspermidine + H2O <=> Acetate + Spermidine
N-(2-Phenylethyl)-acetamide + H2O <=> Phenethylamine + Acetate
N-Benzylformamide + H2O <=> Formate + Benzylamine
GTP + 3 H2O <=> 2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 Orthophosphate
dCTP + 2 H2O <=> dUMP + Diphosphate + Ammonia
(R)-2-Haloacid + H2O <=> (S)-2-Hydroxyacid + Halide
(S)-2-Haloacid + H2O <=> (S)-2-Hydroxyacid + Halide
(R)-2-Haloacid + H2O <=> (R)-2-Hydroxyacid + Halide
2'-Hydroxybiphenyl-2-sulfinate + H2O <=> 2-Hydroxybiphenyl + Sulfite
4-Hydroxyphenylacetate + H+ <=> 4-Cresol + CO2
D-Dopachrome <=> 5,6-Dihydroxyindole + CO2
(3S)-3-Hydroxyacyl-CoA <=> (3E)-3-Enoyl-CoA + H2O
Carbamate <=> Ammonia + CO2
2,7,4'-Trihydroxyisoflavanone <=> Daidzein + H2O
7alpha,12alpha-Dihydroxy-3-oxochol-4-enoate <=> 12alpha-Hydroxy-3-oxochola-4,6-dienoate + H2O
alpha-Maltose <=> beta-Maltose
Violaxanthin <=> Capsorubin
Antheraxanthin <=> Capsanthin
Squalene <=> Diploptene
Squalene + H2O <=> Diplopterol
D-Glucose 6-phosphate <=> 1D-myo-Inositol 3-phosphate
Alcohol + NAD+ <=> Aldehyde + NADH + H+
Alcohol + NADP+ <=> Aldehyde + NADPH + H+
(2S)-Flavanone + 2-Oxoglutarate + Oxygen <=> (2R,3R)-Dihydroflavonol + Succinate + CO2
S-Adenosyl-L-methionine + Catechol <=> S-Adenosyl-L-homocysteine + Guaiacol
S-Adenosyl-L-methionine + 4'-Hydroxyisoflavone <=> S-Adenosyl-L-homocysteine + 4'-Methoxyisoflavone
UDP-glucose + Isoflavone <=> UDP + Isoflavone 7-O-beta-D-glucoside
UDP-glucose + Flavanone <=> UDP + Flavanone 7-O-beta-D-glucoside
beta-D-Glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminylproteoglycan + UDP-N-acetyl-alpha-D-glucosamine <=> UDP + N-Acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminylproteoglycan
UDP-glucuronate + N-Acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosylproteoglycan <=> UDP + beta-D-Glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosylproteoglycan
UDP-glucuronate + N-Acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan <=> UDP + beta-D-Glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan
UDP-L-rhamnose + Flavanone 7-O-beta-D-glucoside <=> UDP + Flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside]
UDP-glucose + Flavonol <=> UDP + Flavonol 7-O-beta-D-glucoside
UDP-glucose + Flavonol 3-O-beta-D-glucoside <=> UDP + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
UDP-glucose + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside <=> UDP + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside
Phenyl acetate + H2O <=> Phenol + Acetate
Chalcone <=> Flavanone
(-)-Usnic acid + NADH + H+ <=> (6R)-2-Acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methyl-2,4-cyclohexadien-1-one + NAD+
D-Sorbitol + NADP+ <=> L-Sorbose + NADPH + H+
(2R,3R)-Flavan-3-ol + 2 NAD+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADH + H+
(2R,3R)-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+
6-(2-Amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 Oxygen <=> PQQ + 2 Hydrogen peroxide + 2 H2O
Tetrahydropteridine + NAD+ <=> Dihydropteridine + NADH + H+
Tetrahydropteridine + NADP+ <=> Dihydropteridine + NADPH + H+
Prenyl-L-cysteine + Oxygen + H2O <=> Prenal + L-Cysteine + Hydrogen peroxide
D-Tryptophan + Oxygen <=> N-Formyl-D-kynurenine
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Oxygen <=> 3-(Methylthio)propanoate + Formate + CO
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Oxygen <=> 4-Methylthio-2-oxobutanoic acid + Formate
Leucocyanidin + 2-Oxoglutarate + Oxygen <=> cis-Dihydroquercetin + Succinate + CO2 + H2O
Flavanone + 2-Oxoglutarate + Oxygen <=> Flavone + Succinate + CO2 + H2O
Dihydroflavonol + 2-Oxoglutarate + Oxygen <=> Flavonol + Succinate + CO2 + H2O
Senecionine + NADPH + H+ + Oxygen <=> Senecionine N-oxide + NADP+ + H2O
S-Adenosyl-L-methionine + 7-Hydroxyisoflavone <=> S-Adenosyl-L-homocysteine + 7-Methoxyisoflavone
Phosphatidylethanolamine + L-Serine <=> Phosphatidylserine + Ethanolamine
Phosphatidylcholine + L-Serine <=> Phosphatidylserine + Choline
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate
1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycerol + Ethanolamine phosphate
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-Alkenyl-2-acylglycerol + Ethanolamine phosphate
1-(1-Alkenyl)-sn-glycero-3-phosphate + Acyl-CoA <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + CoA
2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + H2O <=> 1-Alkenyl-2-acylglycerol + Orthophosphate
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + Ethanolamine
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + Choline <=> Plasmenylcholine + Ethanolamine
1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate
1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphate + Ethanolamine
1-Alkyl-2-acylglycerol + CDP-choline <=> 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + CMP
2 Phosphatidylglycerol <=> Cardiolipin + Glycerol
S-Methyl-5-thio-D-ribulose 1-phosphate <=> 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O
2,3-Diketo-5-methylthiopentyl-1-phosphate <=> 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O <=> 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate
2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O <=> 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate
4-Methylthio-2-oxobutanoic acid + L-Glutamate <=> L-Methionine + 2-Oxoglutarate
UDP-N-acetyl-alpha-D-glucosamine + 3-beta-D-Glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein <=> UDP + alpha-N-Acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosylproteoglycan
6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O <=> 6-(alpha-D-Glucosaminyl)-1D-myo-inositol + Phosphatidate
Acetyl-CoA + Pyruvate + H2O <=> (R)-2-Methylmalate + CoA
Cephalosporin C + H2O + Oxygen <=> (7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + Ammonia + Hydrogen peroxide
(7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + Hydrogen peroxide <=> (7R)-7-(4-Carboxybutanamido)cephalosporanate + CO2 + H2O
(7R)-7-(4-Carboxybutanamido)cephalosporanate + H2O <=> 7-Aminocephalosporanic acid + Glutarate
ATP + Aminoimidazole ribotide + HCO3- <=> ADP + Orthophosphate + 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole <=> 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
2-Amino-3-oxo-4-phosphonooxybutyrate <=> 3-Amino-2-oxopropyl phosphate + CO2
L-Aspartate + NADP+ <=> Iminoaspartate + NADPH + H+
L-Aspartate + NAD+ <=> Iminoaspartate + NADH + H+
Heme + H2O + trans,trans-Farnesyl diphosphate <=> Heme O + Diphosphate
Digalacturonate + H2O <=> 2 D-Galacturonate
ATP + L-Glutamate + Putrescine <=> ADP + Orthophosphate + gamma-L-Glutamylputrescine
gamma-L-Glutamylputrescine + H2O + Oxygen <=> gamma-Glutamyl-gamma-aminobutyraldehyde + Ammonia + Hydrogen peroxide
ATP + N-Methylanthranilate + CoA <=> AMP + Diphosphate + N-Methylanthraniloyl-CoA
gamma-Glutamyl-gamma-aminobutyraldehyde + NAD+ + H2O <=> 4-(L-gamma-Glutamylamino)butanoate + NADH + H+
gamma-Glutamyl-gamma-aminobutyraldehyde + NADP+ + H2O <=> 4-(L-gamma-Glutamylamino)butanoate + NADPH + H+
4-(L-gamma-Glutamylamino)butanoate + H2O <=> 4-Aminobutanoate + L-Glutamate
Phosphocreatine <=> Creatinine + Orthophosphate
UDP-glucose + DIBOA <=> UDP + DIBOA-glucoside
Campesterol <=> Campest-4-en-3beta-ol
Campest-4-en-3beta-ol + NAD+ <=> Campest-4-en-3-one + NADH + H+
Campest-4-en-3-one + NADPH + H+ <=> 5alpha-Campestan-3-one + NADP+
6-Oxocampestanol + Oxygen + NADPH <=> Cathasterone + NADP+ + H2O
p-Coumaroyl-CoA + Quinate <=> CoA + p-Coumaroyl quinic acid
5-O-Caffeoylshikimic acid + CoA <=> Caffeoyl-CoA + Shikimate
p-Coumaroyl-CoA <=> Caffeoyl-CoA
4-Hydroxycinnamyl aldehyde + NADPH + H+ <=> 4-Coumaryl alcohol + NADP+
Ferulate + NADPH + H+ + Oxygen <=> 5-Hydroxyferulic acid + NADP+ + H2O
Sinapoyl aldehyde + NAD+ + H2O <=> Sinapate + NADH + H+
Sinapoyl aldehyde + NADP+ + H2O <=> Sinapate + NADPH + H+
Teasterone <=> 3-Dehydroteasterone
(22S)-22-Hydroxycampest-4-en-3-one + NADPH + H+ <=> 22alpha-Hydroxy-5alpha-campestan-3-one + NADP+
6-Deoxocathasterone + Oxygen <=> 6-Deoxoteasterone + H2O
6-Deoxoteasterone <=> 3-Dehydro-6-deoxoteasterone
D-Glyceraldehyde 3-phosphate + D-Ribulose 5-phosphate + L-Glutamine <=> Pyridoxal phosphate + L-Glutamate + Orthophosphate + 3 H2O
Sulfur-carrier protein + ATP <=> Adenylyl-[sulfur-carrier protein] + Diphosphate
[Enzyme]-cysteine + L-Cysteine <=> [Enzyme]-S-sulfanylcysteine + L-Alanine
Glycine + Oxygen <=> Iminoglycine + Hydrogen peroxide
5alpha-Campestan-3-one <=> Campestanol
6alpha-Hydroxycampestanol <=> 6-Oxocampestanol
3-Dehydroteasterone <=> Typhasterol
Typhasterol + NADPH + H+ + Oxygen <=> Castasterone + NADP+ + H2O
22alpha-Hydroxy-5alpha-campestan-3-one <=> 6-Deoxocathasterone
3-Dehydro-6-deoxoteasterone <=> 6-Deoxotyphasterol
6-Deoxotyphasterol + NADPH + H+ + Oxygen <=> 6-Deoxocastasterone + NADP+ + H2O
Geranylgeranyl diphosphate + Isopentenyl diphosphate <=> all-trans-Pentaprenyl diphosphate + Diphosphate
(2R)-O-Phospho-3-sulfolactate <=> Sulfite + Phosphoenolpyruvate
Spermidine + NAD+ <=> Dehydrospermidine + NADH + H+
N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ <=> [eIF5A-precursor]-deoxyhypusine + NAD+
Dehydrospermidine + [eIF5A-precursor]-lysine <=> N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + 1,3-Diaminopropane
N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + [eIF5A-precursor]-lysine <=> N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + [eIF5A-precursor]-lysine
Cycloartenol + S-Adenosyl-L-methionine <=> 24-Methylidenecycloartanol + S-Adenosyl-L-homocysteine
4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+ <=> 4alpha-Methylfecosterol + NADP+
4alpha-Methylfecosterol <=> 24-Methylenelophenol
5-Dehydroavenasterol <=> Isofucosterol
Isofucosterol + NADPH + H+ <=> beta-Sitosterol + NADP+
beta-Sitosterol + NADPH + H+ + Oxygen <=> Stigmasterol + NADP+ + 2 H2O
5-Dehydroepisterol <=> 24-Methylenecholesterol
24-Methylenecholesterol + NADPH + H+ <=> Campesterol + NADP+
4alpha-Methylzymosterol-4-carboxylate + NADP+ <=> 3-Keto-4-methylzymosterol + NADPH + H+ + CO2
3-Keto-4-methylzymosterol + NADPH + H+ <=> 4alpha-Methylzymosterol + NADP+
Fecosterol <=> Episterol
Zymosterol + NADPH + H+ <=> 5alpha-Cholest-8-en-3beta-ol + NADP+
14-Demethyllanosterol + NADPH + H+ <=> 4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+
Phytyl diphosphate + Homogentisate <=> 2-Methyl-6-phytylquinol + Diphosphate + CO2
2-Methyl-6-phytylquinol + S-Adenosyl-L-methionine <=> 2,3-Dimethyl-5-phytylquinol + S-Adenosyl-L-homocysteine
2,3-Dimethyl-5-phytylquinol <=> gamma-Tocopherol
2-Methyl-6-phytylquinol <=> delta-Tocopherol
delta-Tocopherol + S-Adenosyl-L-methionine <=> beta-Tocopherol + S-Adenosyl-L-homocysteine
5-Dehydroepisterol + NADPH + H+ + Oxygen <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP+ + 2 H2O
7-Dehydrodesmosterol + NADPH + H+ <=> 7-Dehydrocholesterol + NADP+
beta-Tocopherol <=> alpha-Tocopherol
15-cis-Phytoene <=> 9,9'-dicis-zeta-Carotene
7,9,7',9'-tetracis-Lycopene <=> Lycopene
17-O-Acetylajmaline + H2O <=> Ajmaline + Acetate
2,6-Dihydroxypseudooxynicotine + H2O <=> 2,6-Dihydroxypyridine + 4-Methylaminobutyrate
gamma-Carotene + H2O <=> 1'-Hydroxy-gamma-carotene
1'-Hydroxy-gamma-carotene <=> 1'-Hydroxytorulene
Lycopene + H2O <=> 1-Hydroxy-1,2-dihydrolycopene
3,4-Dehydrorhodopin + S-Adenosyl-L-methionine <=> Anhydrorhodovibrin + S-Adenosyl-L-homocysteine
Anhydrorhodovibrin + H2O <=> Rhodovibrin
Rhodovibrin <=> Hydroxyspirilloxanthin
Hydroxyspirilloxanthin + S-Adenosyl-L-methionine <=> Spirilloxanthin + S-Adenosyl-L-homocysteine
1-Hydroxy-1,2-dihydrolycopene + S-Adenosyl-L-methionine <=> 3,4-Dihydroanhydrorhodovibrin + S-Adenosyl-L-homocysteine
3,4-Dihydroanhydrorhodovibrin + H2O <=> 3',4'-Dihydrorhodovibrin
3',4'-Dihydrorhodovibrin + S-Adenosyl-L-methionine <=> 3,4,3',4'-Tetrahydrospirilloxanthin + S-Adenosyl-L-homocysteine
all-trans-Neurosporene + H2O <=> Chloroxanthin
Chloroxanthin + S-Adenosyl-L-methionine <=> 3,4-Dihydrospheroidene + S-Adenosyl-L-homocysteine
Chloroxanthin <=> Demethylspheroidene
Demethylspheroidene + S-Adenosyl-L-methionine <=> Spheroidene + S-Adenosyl-L-homocysteine
Spheroidene + H2O <=> Hydroxyspheroidene
Spheroidenone + H2O <=> Hydroxyspheroidenone
gamma-Carotene <=> 1',2'-Dihydro-gamma-carotene
gamma-Carotene <=> 1',2'-Dihydrochlorobactene
Chlorobactene + H2O <=> Hydroxychlorobactene
Hydroxychlorobactene <=> Hydroxychlorobactene glucoside
Hydroxychlorobactene glucoside <=> Hydroxychlorobactene glucoside ester
1'-Hydroxy-gamma-carotene <=> 1'-Hydroxy-gamma-carotene glucoside
1'-Hydroxy-gamma-carotene glucoside <=> 1'-Hydroxy-gamma-carotene glucoside ester
gamma-Carotene <=> Myxol
Myxol <=> 4-Ketomyxol
Myxol <=> 4-Hydroxymyxol
4-Ketomyxol <=> 4-Hydroxymyxol
gamma-Carotene <=> Deoxymyxol
Deoxymyxol <=> (2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside)
(2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside) <=> (3R,2'S)-Myxol 2'-(2,4-di-O-methyl-alpha-L-fucoside)
gamma-Carotene <=> (2'S)-Deoxymyxol 2'-alpha-L-fucoside
(2'S)-Deoxymyxol 2'-alpha-L-fucoside <=> (3R,2'S)-Myxol 2'-alpha-L-fucoside
Zeaxanthin + 2 UDP-glucose <=> Zeaxanthin diglucoside + 2 UDP
Abscisate + UDP-glucose <=> Abscisic acid glucose ester + UDP
8'-Hydroxyabscisate <=> Phaseic acid
Phaseic acid <=> Dihydrophaseic acid
beta-Cryptoxanthin <=> Thermocryptoxanthin
Thermocryptoxanthin <=> Thermozeaxanthin
Zeaxanthin <=> Thermozeaxanthin
Thermozeaxanthin <=> Thermobiszeaxanthin
(9S,10S)-10-Hydroxy-9-(phosphonooxy)octadecanoate + H2O <=> (9S,10S)-9,10-Dihydroxyoctadecanoate + Orthophosphate
Phytic acid + H2O <=> 1L-myo-Inositol 1,2,3,4,6-pentakisphosphate + Orthophosphate
Phytic acid + H2O <=> myo-Inositol pentakisphosphate + Orthophosphate
Cholesterol-5alpha,6alpha-epoxide + H2O <=> 3beta,5alpha,6beta-Cholestanetriol
L-Lysine + Oxygen + H2O <=> L-2-Aminoadipate 6-semialdehyde + Hydrogen peroxide + Ammonia
3-Methyl-2-oxobutanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxypropyl-ThPP + CO2
2-Methyl-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + Thiamin diphosphate
4-Methyl-2-oxopentanoate + Thiamin diphosphate <=> 3-Methyl-1-hydroxybutyl-ThPP + CO2
3-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
(S)-3-Methyl-2-oxopentanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxybutyl-ThPP + CO2
2-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
7-Aminomethyl-7-carbaguanine + 2 NADP+ <=> 7-Cyano-7-carbaguanine + 2 NADPH + 2 H+
L-Methionine + Thioredoxin disulfide + H2O <=> L-Methionine (S)-S-oxide + Thioredoxin
Peptide-L-methionine + Thioredoxin disulfide + H2O <=> Peptide-L-methionine (R)-S-oxide + Thioredoxin
L-Methionine + Thioredoxin disulfide + H2O <=> L-Methionine (R)-S-oxide + Thioredoxin
LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate <=> 2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
Protein-omega-N-(ADP-D-ribosyl)-L-arginine + H2O <=> ADP-ribose + Protein-L-arginine
cis-Stilbene oxide + H2O <=> (+)-(1R,2R)-1,2-Diphenylethane-1,2-diol
3-Oxo-3-ureidopropanoate + H2O <=> Malonate + Urea
trans,trans-Farnesyl diphosphate <=> Amorpha-4,11-diene + Diphosphate
Geranyl diphosphate + H2O <=> (+)-Linalool + Diphosphate
Geranyl diphosphate + H2O <=> (-)-Linalool + Diphosphate
(2R)-3-Sulfolactate <=> Pyruvate + HSO3-
L-Cysteate + H2O <=> Pyruvate + HSO3- + Ammonia
6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol <=> 6-(alpha-D-Glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + 1,2-Diacyl-sn-glycerol
FAD <=> AMP + Riboflavin cyclic-4',5'-phosphate
(Z)-Phenylacetaldehyde oxime <=> Phenylacetonitrile + H2O
trans-Dec-2-enoyl-[acp] <=> cis-Dec-3-enoyl-[acp]
ATP + RNA(n) + RNA(m) <=> AMP + Diphosphate + RNA(n+m)
2 ATP + HCO3- + Ammonia <=> 2 ADP + Orthophosphate + Carbamoyl phosphate
ATP + L-Amino acid + L-Amino acid <=> ADP + Orthophosphate + L-Aminoacyl-L-amino acid
trans,trans-Farnesyl diphosphate + H2O <=> (1E,4S,5E,7R)-Germacra-1(10),5-dien-11-ol + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-Germacrene D + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Germacrene A + Diphosphate
L-2,4-Diaminobutanoate <=> 1,3-Diaminopropane + CO2
D-Alanyl-D-alanine + H2O <=> 2 D-Alanine
2 trans,trans-Farnesyl diphosphate <=> 4,4'-Diapophytoene + 2 Diphosphate
4,4'-Diaponeurosporenic acid <=> Glucosyl-4,4'-diaponeurosporenoate
Glucosyl-4,4'-diaponeurosporenoate <=> Staphyloxanthin
1-Hydroxy-2-naphthoate + Oxygen <=> (3Z)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate
UDP-glucuronate + NAD+ <=> UDP-L-Ara4O + CO2 + NADH + H+
UDP-L-Ara4O + L-Glutamate <=> UDP-L-Ara4N + 2-Oxoglutarate
10-Formyltetrahydrofolate + UDP-L-Ara4N <=> Tetrahydrofolate + UDP-L-Ara4FN
UDP-L-Ara4FN + di-trans,poly-cis-Undecaprenyl phosphate <=> Undecaprenyl phosphate alpha-L-Ara4FN + UDP
Undecaprenyl phosphate alpha-L-Ara4FN + H2O <=> Undecaprenyl phosphate alpha-L-Ara4N + Formate
Toluene-4-sulfonate + Oxygen <=> 4-Cresol + Sulfate
(S)-Mandelate + FMN <=> alpha-Oxo-benzeneacetic acid + Reduced FMN
3-Cresol + Oxygen + NADH + H+ <=> 3-Hydroxybenzyl alcohol + NAD+ + H2O
3-Hydroxybenzaldehyde + NADP+ + H2O <=> 3-Hydroxybenzoate + NADPH + H+
3-Hydroxybenzaldehyde + NAD+ + H2O <=> 3-Hydroxybenzoate + NADH + H+
Vanillate + Cob(I)alamin <=> 3,4-Dihydroxybenzoate + Methylcobalamin
beta-1,2,3,4,5,6-Hexachlorocyclohexane + H2O <=> beta-2,3,4,5,6-Pentachlorocyclohexanol + Hydrochloric acid
beta-2,3,4,5,6-Pentachlorocyclohexanol + H2O <=> beta-2,3,5,6-Tetrachloro-1,4-cyclohexanediol + Hydrochloric acid
Protein N(pi)-phospho-L-histidine + Ascorbate <=> Protein histidine + L-Ascorbate 6-phosphate
GDP-mannose <=> GDP-L-gulose
GDP-L-gulose <=> GDP-L-galactose
beta-L-Galactose 1-phosphate + H2O <=> L-Galactose + Orthophosphate
L-Galactose + NAD+ <=> L-Galactono-1,4-lactone + NADH + H+
L-Galactonate + NADP+ <=> D-Galacturonate + NADPH + H+
L-Ascorbate 6-phosphate + H2O <=> 3-Dehydro-L-gulonate 6-phosphate
GDP-L-galactose + D-Mannose 1-phosphate <=> beta-L-Galactose 1-phosphate + GDP-mannose
L-Galactono-1,4-lactone + H2O <=> L-Galactonate
1,6-Naphthalenedisulfonic acid + Oxygen <=> 1,2-Dihydroxynaphthalene-6-sulfonate + Sulfite
2,6-Naphthalenedisulfonic acid + Oxygen <=> 1,2-Dihydroxynaphthalene-6-sulfonate + Sulfite
1,2-Dihydroxynaphthalene-6-sulfonate + Oxygen <=> (Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate
(Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate + 2 H2O <=> 5-Sulfosalicylate + Pyruvate
5-Sulfosalicylate + Oxygen <=> 2,5-Dihydroxybenzoate + Sulfate
Anthracene-9,10-dihydrodiol <=> 9,10-Dihydroxyanthracene + 2 H+
9,10-Dihydroxyanthracene <=> Anthraquinone + 2 H+
3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate <=> 1,2-Dihydrophthalic acid
3-Hydroxy-2-naphthoate + Oxygen <=> 3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate
4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid + 2 H2O <=> 3-Hydroxy-2-naphthoate + Pyruvate
4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid <=> 6,7-Benzocoumarin
1,2-Anthracenediol <=> 1-Methoxy-2-hydroxyanthracene
2,3-Dihydroxynaphthalene <=> Salicylate
3-Hydroxy-2-naphthoate <=> 2,3-Dihydroxynaphthalene
Phenylboronic acid + Oxygen <=> Phenol + Boric acid
1-Naphthalenesulfonic acid + Oxygen <=> Naphthalene-1,2-diol + Sulfite
2-Naphthalenesulfonic acid + Oxygen <=> Naphthalene-1,2-diol + Sulfite
Aniline + Oxygen <=> Catechol + Ammonia
1,2-Anthracenediol + Oxygen <=> 4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid
1,2-Anthracenediol + Oxygen <=> 3-(2-Carboxyvinyl)naphthalene-2-carboxylic acid
1,2-Dihydrophthalic acid + NAD+ <=> Phthalate + NADH + H+
Anthracene + Oxygen + NADH + H+ <=> Anthracene-cis-1,2-dihydrodiol + NAD+
Anthracene-cis-1,2-dihydrodiol + NAD+ <=> 1,2-Anthracenediol + NADH + H+
Nitrobenzene + Oxygen + NADH + H+ <=> Catechol + Nitrite + NAD+
Phenanthrene-9,10-oxide <=> 9-Hydroxyphenanthrene
trans-9(S),10(S)-Dihydrodiolphenanthrene <=> 9-Hydroxyphenanthrene + H2O
Salicylate + NADH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NAD+ + H2O
Salicylate + NADPH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NADP+ + H2O
Liquiritigenin + NADPH + H+ + Oxygen <=> 6,7,4'-Trihydroxyflavanone + NADP+ + H2O
Liquiritigenin + 2-Oxoglutarate + Oxygen <=> 7,4'-Dihydroxyflavone + Succinate + CO2 + H2O
(3Z)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate + H2O <=> 2-Carboxybenzaldehyde + Pyruvate
7,4'-Dihydroxyflavone + 2 NADPH + 2 H+ + Oxygen <=> 2,7,4'-Trihydroxyisoflavanone + 2 NADP+ + H2O
2,6,7,4'-Tetrahydroxyisoflavanone <=> 4',6,7-Trihydroxyisoflavone
4',6,7-Trihydroxyisoflavone <=> Glycitein
Glycitein + UDP-glucose <=> Glycitin + UDP
Glycitin + Malonyl-CoA <=> Malonylglycitin + CoA
Daidzein + UDP-glucose <=> Daidzin + UDP
Daidzin + Malonyl-CoA <=> Malonyldaidzin + CoA
S-Adenosyl-L-methionine + 2,7,4'-Trihydroxyisoflavanone <=> S-Adenosyl-L-homocysteine + 2,7-Dihydroxy-4'-methoxyisoflavanone
2,7-Dihydroxy-4'-methoxyisoflavanone <=> Formononetin + H2O
Daidzein + S-Adenosyl-L-methionine <=> Isoformononetin + S-Adenosyl-L-homocysteine
Daidzein <=> Anhydroglycinol
Anhydroglycinol <=> Coumestrol
o-Nitrobenzoate + 2 NADPH + 2 H+ <=> o-Hydroxylaminobenzoate + 2 NADP+ + H2O
2'-Hydroxydihydrodaidzein + NADPH + H+ <=> 3,9-Dihydroxypterocarpan + NADP+ + H2O
Formononetin + UDP-glucose <=> Ononin + UDP
o-Hydroxylaminobenzoate <=> 3-Hydroxyanthranilate
Ononin + Malonyl-CoA <=> Formononetin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA
Formononetin 7-O-(6-O-malonyl-beta-D-glucoside) <=> Ononin
Ononin <=> Formononetin
o-Hydroxylaminobenzoate + 2 H+ <=> Anthranilate + H2O
2'-Hydroxyformononetin <=> 7-Hydroxy-2',4',5'-trimethoxyisoflavone
7-Hydroxy-2',4',5'-trimethoxyisoflavone <=> 9-Demethylmunduserone
(-)-Vestitone + NADPH + H+ <=> 7,2'-Dihydroxy-4'-methoxy-isoflavanol + NADP+
7,2'-Dihydroxy-4'-methoxy-isoflavanol <=> Medicarpin + H2O
Medicarpin + NADPH + H+ <=> (-)-Vestitol + NADP+
Medicarpin + UDP-glucose <=> (-)-Medicocarpin + UDP
(-)-Medicocarpin + Malonyl-CoA <=> Medicarpin 3-O-glucoside-6'-malonate + CoA
Medicarpin 3-O-glucoside-6'-malonate <=> (-)-Medicocarpin
(-)-Medicocarpin <=> Medicarpin
Calycosin <=> Rotenone
2',7-Dihydroxy-4',5'-methylenedioxyisoflavone + NADPH + H+ <=> (+)-Sophorol + NADP+
(+)-Sophorol + NADPH + H+ <=> (+)-Maackiain + NADP+ + H2O
(+)-Maackiain <=> (+)-6a-Hydroxymaackiain
(+)-6a-Hydroxymaackiain + S-Adenosyl-L-methionine <=> Pisatin + S-Adenosyl-L-homocysteine
2',7-Dihydroxy-4',5'-methylenedioxyisoflavone + NADPH + H+ <=> (-)-Sophorol + NADP+
(-)-Sophorol + NADPH + H+ <=> (-)-Maackiain + NADP+ + H2O
(-)-Maackiain + UDP-glucose <=> Trifolirhizin + UDP
Trifolirhizin + Malonyl-CoA <=> (-)-Maackiain-3-O-glucosyl-6''-O-malonate + CoA
(-)-Maackiain-3-O-glucosyl-6''-O-malonate <=> Trifolirhizin
Trifolirhizin <=> (-)-Maackiain
Genistin + Malonyl-CoA <=> Malonylgenistin + CoA
Malonyl-CoA + Palmitoyl-CoA <=> 3-Oxostearoyl-CoA + CoA + CO2
3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+
3-Hydroxyoctadecanoyl-CoA <=> (2E)-Octadecenoyl-CoA + H2O
(2E)-Octadecenoyl-CoA + NADPH + H+ <=> Stearoyl-CoA + NADP+
Hexadecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxostearoyl-[acp] + Acyl-carrier protein + CO2
3-Oxostearoyl-[acp] + NADPH + H+ <=> (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein] + NADP+
(3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein] <=> (2E)-Octadecenoyl-[acp] + H2O
(2E)-Octadecenoyl-[acp] + NADH + H+ <=> Octadecanoyl-[acyl-carrier protein] + NAD+
Octanoyl-[acp] + [Lipoyl-carrier protein]-L-lysine <=> [Protein]-N6-(octanoyl)-L-lysine + Acyl-carrier protein
Lipoyl-[acp] + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + Acyl-carrier protein
ATP + (R)-Lipoate <=> Diphosphate + Lipoyl-AMP
Lipoyl-AMP + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + AMP
Cobalt-precorrin 5A + H2O <=> Cobalt-precorrin 5B + Acetaldehyde
Cobalt-precorrin 5B + S-Adenosyl-L-methionine <=> Cobalt-precorrin 6 + S-Adenosyl-L-homocysteine
Cobalt-dihydro-precorrin 6 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 7 + S-Adenosyl-L-homocysteine + CO2
Cobalt-precorrin 7 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 8 + S-Adenosyl-L-homocysteine
Bromoxynil + 2 NADPH + 2 H+ + Oxygen <=> 2,6-Dibromohydroquinone + 2 NADP+ + Hydrogen cyanide + H2O
Bromoxynil + H2O <=> 3,5-Dibromo-4-hydroxybenzamide
2-Bromomaleylacetate + NADH + H+ <=> 2-Maleylacetate + NAD+ + Bromide
3,5-Dibromo-4-hydroxybenzamide + H2O <=> 3,5-Dibromo-4-hydroxybenzoate + Ammonia
3,5-Dibromo-4-hydroxybenzoate <=> 2,6-Dibromophenol
2,6-Dibromophenol <=> 2,6-Dibromohydroquinone
2,6-Dibromohydroquinone <=> 2-Bromomaleylacetate
22alpha-Hydroxy-5alpha-campestan-3-one <=> 3-epi-6-Deoxocathasterone
(22R,23R)-22,23-Dihydroxycampesterol <=> (22R,23R)-22,23-Dihydroxy-campest-4-en-3-one
(22R,23R)-22,23-Dihydroxy-campest-4-en-3-one <=> 3-Dehydro-6-deoxoteasterone
4-Chloroaniline + Oxygen + 2 H+ <=> 4-Chlorocatechol + Ammonia
2,4-Dichloroaniline + 2 H+ <=> 4-Chloroaniline + Hydrochloric acid
3-Sulfocatechol + Oxygen + H2O <=> 2-Hydroxymuconate + Sulfite
(E)-Cinnamoyl-CoA + Phenyllactate <=> trans-Cinnamate + (R)-Phenyllactyl-CoA
3'-Phosphoadenylyl sulfate + Petromyzonol <=> Adenosine 3',5'-bisphosphate + Petromyzonol 24-sulfate
3'-Phosphoadenylyl sulfate + Scymnol <=> Adenosine 3',5'-bisphosphate + 5beta-Scymnol sulfate
Fluoren-9-one + Oxygen + H+ + NADH <=> 1-Hydro-1,1a-dihydroxy-9-fluorenone + NAD+
1-Hydro-1,1a-dihydroxy-9-fluorenone + H2O <=> 2,3-Dihydroxy-2'-carboxybiphenyl + 2 H+
2,3-Dihydroxy-2'-carboxybiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate
2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O <=> Phthalate + 2-Hydroxy-2,4-pentadienoate
3-Isochromanone <=> Catechol
(+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene <=> 3,4-Dihydroxyfluorene + 2 H+
4-Coumarate <=> Caffeate
3-Chlorocatechol + Oxygen <=> 3-Chloro-2-hydroxymuconic semialdehyde
Cyclopropanecarboxylate + CoA + ATP <=> Cyclopropanecarboxyl-CoA + ADP + Orthophosphate
Cyclopropanecarboxyl-CoA <=> Crotonoyl-CoA
trans,trans-Farnesyl diphosphate <=> (+)-epi-Isozizaene + Diphosphate
Dihydrophloroglucinol + H2O <=> 3-Hydroxy-5-oxohexanoate
3-Hydroxy-5-oxohexanoate + Acetyl-CoA <=> 3-Hydroxy-5-oxohexanoyl-CoA + Acetate
3-Hydroxy-5-oxohexanoyl-CoA + CoA <=> (S)-3-Hydroxybutanoyl-CoA + Acetyl-CoA
1-Hydroxy-1,2-dihydrolycopene <=> Rhodopinal
Terephthalate + H2O <=> Benzoate + Carbonic acid
Thiobenzamide + Oxygen + NADPH + H+ <=> Thiobenzamide S-oxide + NADP+ + H2O
Thiobenzamide S-oxide + NADPH + H+ + Oxygen <=> Thiobenzamide S,S-dioxide + NADP+ + H2O
Thiobenzamide S,S-dioxide <=> Benzonitrile
(1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
delta-Carotene <=> epsilon-Carotene
Zeaxanthin <=> Caloxanthin
Caloxanthin <=> Nostoxanthin
Rhodopinal <=> Rhodopinal glucoside
Lycopene <=> (2S,2'S)-Oscillol
(2S,2'S)-Oscillol <=> (2S,2'S)-Oscillol 2,2'-di(alpha-L-fucoside)
Lycopene <=> R.g.-Keto I
R.g.-Keto I <=> R.g.-Keto III
R.g.-Keto I <=> Thiothece-474
gamma-Carotene <=> (2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside)
Phenylacetonitrile + H2O <=> 2-Phenylacetamide
Phenylacetonitrile + 2 H2O <=> Phenylacetic acid + Ammonia
beta-Zeacarotene <=> 7,8-Dihydro-beta-carotene
Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid
Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid
1'-Hydroxytorulene <=> Deinoxanthin
13(S)-HPOT <=> (9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid + H2O
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 9(S)-HPOT
9(S)-HPOT <=> 9,10-EOT + H2O
9,10-EOT <=> 10-OPDA
9(S)-HPOT <=> Colnelenic acid + H2O
9(S)-HPOT <=> 9-Oxononanoic acid + 3,6-Nonadienal
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 13(S)-HPOT
13(S)-HPOT <=> 12-Oxo-9(Z)-dodecenoic acid + 3-Hexenal
13(S)-HPOT <=> Etherolenic acid + H2O
12-Oxo-9(Z)-dodecenoic acid <=> Traumatin
Pelargonidin 3-O-glucoside + Caffeoyl-CoA <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-glucoside + UDP-glucose <=> Pelargonin + UDP
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) + UDP-glucose <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + UDP
Pelargonin + Caffeoyl-CoA <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + CoA
Pelargonidin 3-O-glucoside + UDP-glucose <=> Pelargonidin 3-O-sophoroside + UDP
Cyanidin 3-O-glucoside + UDP-glucose <=> Cyanidin 3-O-sophoroside + UDP
Delphinidin 3-O-glucoside + UDP-glucose <=> Delphinidin 3-O-sophoroside + UDP
Pelargonin + p-Coumaroyl-CoA <=> Pelargonidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA
2-Naphthoyl-CoA + H2O <=> 2-Naphthoic acid + CoA
Cyanidin 3,5-O-diglucoside + p-Coumaroyl-CoA <=> Cyanidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA
Delphinidin 3,5-diglucoside + p-Coumaroyl-CoA <=> Delphinidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=> Pelargonidin 3-O-3'',6''-O-dimalonylglucoside + CoA
Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=> Cyanidin 3-O-3'',6''-O-dimalonylglucoside + CoA
Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + Malonyl-CoA <=> Delphinidin 3-O-3'',6''-O-dimalonylglucoside + CoA
ATP + (9S,13S,15Z)-12-Oxo-10,11-dihydrophyto-15-enoate + CoA <=> AMP + Diphosphate + OPC8-CoA
OPC8-CoA + FAD <=> trans-2-Enoyl-OPC8-CoA + FADH2
3-Hydroxy-OPC8-CoA <=> trans-2-Enoyl-OPC8-CoA + H2O
3-Hydroxy-OPC8-CoA + NAD+ <=> 3-Oxo-OPC8-CoA + NADH + H+
OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA
OPC6-CoA + FAD <=> trans-2-Enoyl-OPC6-CoA + FADH2
3-Hydroxy-OPC6-CoA <=> trans-2-Enoyl-OPC6-CoA + H2O
3-Hydroxy-OPC6-CoA + NAD+ <=> 3-Oxo-OPC6-CoA + NADH + H+
OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA
OPC4-CoA + FAD <=> trans-2-Enoyl-OPC4-CoA + FADH2
3-Hydroxy-OPC4-CoA <=> trans-2-Enoyl-OPC4-CoA + H2O
3-Hydroxy-OPC4-CoA + NAD+ <=> 3-Oxo-OPC4-CoA + NADH + H+
(+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA
Cyanidin 3-O-rutinoside <=> Cyanidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Cyanidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Peonidin-3-(p-coumaroyl)-rutinoside-5-glucoside
(+)-7-Isojasmonic acid CoA + H2O <=> CoA + (+)-7-Isojasmonic acid
Delphinidin 3-O-glucoside + UDP-L-rhamnose <=> Delphinidin 3-O-rutinoside + UDP
Delphinidin 3-O-rutinoside <=> Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Petunidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Petunidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Malvidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Malvidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Cyanidin <=> Cyanidin 5-O-glucoside
Cyanidin 5-O-glucoside <=> Cyanidin 3,5-O-diglucoside
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + Malonyl-CoA <=> Malonylshisonin + CoA
Delphinidin 3-O-glucoside + UDP-glucose <=> Delphinidin 3,5-diglucoside + UDP
Delphinidin 3,5-diglucoside + UDP-glucose <=> Delphinidin 3,5,3'-triglucoside + UDP
Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-glucose <=> Delphinidin 3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside + UDP
Delphinidin 3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside + UDP-glucose <=> Ternatin C5 + UDP
Ternatin C5 <=> Ternatin A1
2 Geranylgeranyl diphosphate <=> all-trans-Phytoene + 2 Diphosphate
S-Adenosyl-L-methionine + Xanthosine <=> S-Adenosyl-L-homocysteine + 7-Methylxanthosine
7-Methylxanthosine + H2O <=> 7-Methylxanthine + D-Ribose
S-Adenosyl-L-methionine + 7-Methylxanthine <=> S-Adenosyl-L-homocysteine + Theobromine
S-Adenosyl-L-methionine + Theobromine <=> S-Adenosyl-L-homocysteine + Caffeine
S-Adenosyl-L-methionine + 1,7-Dimethylxanthine <=> S-Adenosyl-L-homocysteine + Caffeine
S-Adenosyl-L-methionine + 7-Methylxanthine <=> S-Adenosyl-L-homocysteine + 1,7-Dimethylxanthine
Delphinidin 3-glucoside 5-caffoyl-glucoside + UDP-glucose <=> Albireodelphin + UDP
Albireodelphin <=> Gentiodelphin
Delphinidin 3,5,3'-triglucoside <=> Gentiodelphin
Delphinidin 3-O-glucoside + Caffeoyl-CoA <=> Delphinidin 3-O-(6-caffeoyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-glucoside + p-Coumaroyl-CoA <=> Pelargonidin 3-(6-p-coumaroyl)glucoside + CoA
Cyanidin 3-O-glucoside + Caffeoyl-CoA <=> Cyanidin 3-(6-p-caffeoyl)glucoside + CoA
Delphinidin 3-O-glucoside + p-Coumaroyl-CoA <=> Delphinidin 3-(6-p-coumaroyl)glucoside + CoA
Pelargonin + Caffeoyl-CoA <=> Pelargonidin 3-glucoside 5-caffeoylglucoside + CoA
Cyanidin 3,5-O-diglucoside + Caffeoyl-CoA <=> Cyanidin 3-glucoside 5-caffeoylglucoside + CoA
Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + UDP-glucuronate <=> Cyanidin-3-O-(6''-O-malonyl-2''-O-glucuronyl)glucoside + UDP
(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA + Oxygen <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + Hydrogen peroxide
(3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + H2O
(3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA + NADH + H+
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA
Delphinidin 3-O-glucoside + Malonyl-CoA <=> Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + CoA
Caffeine + NADPH + Oxygen + H+ <=> 1,7-Dimethylxanthine + NADP+ + Formaldehyde + H2O
1,7-Dimethylxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil
5-Acetylamino-6-formylamino-3-methyluracil <=> 5-Acetylamino-6-amino-3-methyluracil
1-Methylxanthine + H2O + Oxygen <=> 1-Methyluric acid + Hydrogen peroxide
1,7-Dimethylxanthine <=> 1-Methylxanthine
Delphinidin 3,5-diglucoside + Caffeoyl-CoA <=> Delphinidin 3-glucoside 5-caffoyl-glucoside + CoA
1,7-Dimethylxanthine <=> 1,7-Dimethyluric acid
2,6-Dihydroxypseudooxynicotine <=> 2,6-Dihydroxy-N-methylmyosmine + H2O
2 2,3,6-Trihydroxypyridine + 2 Oxygen <=> Blue pigment + 2 Hydrogen peroxide
2,3,6-Trihydroxypyridine + Oxygen + H+ <=> Maleamate + 2 H+ + CO2
(6Z,9Z,12Z,15Z,18Z)-Tetracosapentaenoyl-CoA + Oxygen <=> (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexaenoyl-CoA + Hydrogen peroxide
(3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexaenoyl-CoA + H2O
(3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA + NADH + H+
(4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA
Caffeine + NADH + H+ + Oxygen <=> 1,7-Dimethylxanthine + NAD+ + Formaldehyde + H2O
Caffeine + NADH + H+ + Oxygen <=> Theobromine + NAD+ + Formaldehyde + H2O
Caffeine + NADPH + H+ + Oxygen <=> Theobromine + NADP+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADH + H+ + Oxygen <=> 7-Methylxanthine + NAD+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADPH + H+ + Oxygen <=> 7-Methylxanthine + NADP+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADH + H+ + Oxygen <=> 1-Methylxanthine + NAD+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADPH + H+ + Oxygen <=> 1-Methylxanthine + NADP+ + Formaldehyde + H2O
Theobromine + NADH + H+ + Oxygen <=> 7-Methylxanthine + NAD+ + Formaldehyde + H2O
Theobromine + NADPH + H+ + Oxygen <=> 7-Methylxanthine + NADP+ + Formaldehyde + H2O
Theobromine + NADH + H+ + Oxygen <=> 3-Methylxanthine + NAD+ + Formaldehyde + H2O
Theobromine + NADPH + H+ + Oxygen <=> 3-Methylxanthine + NADP+ + Formaldehyde + H2O
7-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O
7-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O
3-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O
3-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O
1-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O
1-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O
Caffeine + NADH + H+ + Oxygen <=> Theophylline + NAD+ + Formaldehyde + H2O
Caffeine + NADPH + H+ + Oxygen <=> Theophylline + NADP+ + Formaldehyde + H2O
Theophylline + NADH + H+ + Oxygen <=> 3-Methylxanthine + NAD+ + Formaldehyde + H2O
Theophylline + NADPH + H+ + Oxygen <=> 3-Methylxanthine + NADP+ + Formaldehyde + H2O
Theophylline + NADH + H+ + Oxygen <=> 1-Methylxanthine + NAD+ + Formaldehyde + H2O
Theophylline + NADPH + H+ + Oxygen <=> 1-Methylxanthine + NADP+ + Formaldehyde + H2O
1,7-Dimethylxanthine + Oxygen + H2O <=> 1,7-Dimethyluric acid + Hydrogen peroxide
Theobromine + H2O + Oxygen <=> 3,7-Dimethyluric acid + Hydrogen peroxide
7-Methylxanthine + Oxygen + H2O <=> 7-Methyluric acid + Hydrogen peroxide
Caffeine + Ubiquinone + H2O <=> 1,3,7-Trimethyluric acid + Ubiquinol
1,3,7-Trimethyluric acid + Oxygen + 2 H2O <=> 3,6,8-Trimethylallantoin + CO2 + Hydrogen peroxide
3,6,8-Trimethylallantoin + 2 H2O <=> N,N'-Dimethylurea + N-Methylurea + Glyoxylate
2,6-Dihydroxynicotinate + H2O + Oxygen <=> Maleamate + CO2 + Formate
6-Oxo-1,4,5,6-tetrahydronicotinate + 2 H2O <=> 2-Formylglutarate + Ammonia
2-Formylglutarate + NADH + H+ <=> (S)-2-(Hydroxymethyl)glutarate + NAD+
(S)-2-(Hydroxymethyl)glutarate <=> 2-Methyleneglutarate + H2O
Pinocembrin chalcone <=> Pinocembrin
Eriodictyol chalcone <=> Eriodictyol
Homoeriodictyol chalcone <=> Homoeriodictyol
Pinocembrin + 2-Oxoglutarate + Oxygen <=> Pinobanksin + Succinate + CO2
Isoliquiritigenin <=> Butein
Butein <=> Butin
Liquiritigenin + 2-Oxoglutarate + Oxygen <=> Garbanzol + Succinate + CO2
Butin + 2-Oxoglutarate + Oxygen <=> Fustin + Succinate + CO2
5-Deoxyleucopelargonidin + NADP+ <=> Garbanzol + NADPH + H+
Fisetinidol-4beta-ol + NADP+ <=> Fustin + NADPH + H+
5-Deoxyleucopelargonidin <=> Garbanzol
Fisetinidol-4beta-ol <=> Fustin
Naringenin chalcone + Dimethylallyl diphosphate <=> Desmethylxanthohumol + Diphosphate
Desmethylxanthohumol + S-Adenosyl-L-methionine <=> Xanthohumol + S-Adenosyl-L-homocysteine
Eriodictyol chalcone + Oxygen <=> Bracteatin + H2O
Naringenin chalcone + UDP-glucose <=> 2',4,4',6'-Tetrahydroxychalcone 4'-O-glucoside + UDP
Eriodictyol chalcone + UDP-glucose <=> 2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + UDP
2',4,4',6'-Tetrahydroxychalcone 4'-O-glucoside + Oxygen <=> Aureusidin 6-O-glucoside + H2O
2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + Oxygen <=> Bracteatin 6-O-glucoside + H2O
2 2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + Oxygen <=> 2 Aureusidin 6-O-glucoside + 2 H2O
Aureusidin <=> Bracteatin
Eriodictyol <=> Homoeriodictyol
Naringenin chalcone + UDP-glucose <=> Phlorizin chalcone + UDP
Trinitrotoluene + 2 NADPH + 2 H+ <=> 4-Hydroxylamino-2,6-dinitrotoluene + 2 NADP+ + H2O
2,4-Dihydroxylamino-6-nitrotoluene + NADPH + H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + NADP+ + H2O
Trinitrotoluene + 2 NADH + 2 H+ <=> 4-Hydroxylamino-2,6-dinitrotoluene + 2 NAD+ + H2O
4-Hydroxylamino-2,6-dinitrotoluene + NADH + H+ <=> 4-Amino-2,6-dinitrotoluene + NAD+ + H2O
4-Hydroxylamino-2,6-dinitrotoluene + NADPH + H+ <=> 4-Amino-2,6-dinitrotoluene + NADP+ + H2O
4 4-Hydroxylamino-2,6-dinitrotoluene + Oxygen <=> 2 2,2',6,6'-Tetranitro-4,4'-azoxytoluene + 4 H2O
UDP-glucose + Hesperetin <=> UDP + Hesperetin 7-O-glucoside
Hesperetin 7-O-glucoside + UDP-L-rhamnose <=> Neohesperidin + UDP
4-Coumarate <=> Naringin chalcone
Naringin chalcone <=> Naringin
Naringenin <=> Hesperetin
2,4-Diamino-6-nitrotoluene <=> 2,4,6-Triaminotoluene
Pinobanksin <=> Pinobanksin 3-O-acetate
Pinocembrin <=> Pinostrobin
2,6-Diamino-4-nitrotoluene <=> 2,4,6-Triaminotoluene
Eriodictyol chalcone <=> Homoeriodictyol chalcone
2-Amino-4,6-dinitrotoluene <=> 2-Amino-4-nitrotoluene
2,4-Diamino-6-nitrotoluene <=> 2,4-Diamino-6-hydroxylaminotoluene
2,4-Diamino-6-hydroxylaminotoluene <=> 2,4,6-Triaminotoluene
2,4-Diamino-6-nitrotoluene + Acetyl-CoA <=> 4-Acetamido-2-amino-6-nitrotoluene + CoA
2 4-Hydroxylamino-2,6-dinitrotoluene + 2 2-Hydroxylamino-4,6-dinitrotoluene + Oxygen <=> 2 2,4',6,6'-Tetranitro-2',4-azoxytoluene + 4 H2O
4 2-Hydroxylamino-4,6-dinitrotoluene + Oxygen <=> 2 4,4',6,6'-Tetranitro-2,2'-azoxytoluene + 4 H2O
2,4,6-Triaminotoluene <=> 2,4,6-Trihydroxytoluene
2,4,6-Trihydroxytoluene <=> 4-Cresol
Trinitrotoluene + 2 NADH + 2 H+ <=> 2-Hydroxylamino-4,6-dinitrotoluene + 2 NAD+ + H2O
2-Hydroxylamino-4,6-dinitrotoluene + NADH + H+ <=> 2-Amino-4,6-dinitrotoluene + NAD+ + H2O
4-Amino-2,6-dinitrotoluene + 2 NADH + 2 H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + 2 NAD+ + H2O
2,4-Dihydroxylamino-6-nitrotoluene <=> 2-Amino-5-hydroxyl-4-hydroxylamino-6-nitrotoluene
4-Amino-2-hydroxylamino-6-nitrotoluene <=> 2,4-Diamino-6-nitrotoluene
Ectoine + 2-Oxoglutarate + Oxygen <=> 5-Hydroxyectoine + Succinate + CO2
Dimethylallyl diphosphate + ATP <=> Isopentenyladenosine-5'-triphosphate + Diphosphate
Dimethylallyl diphosphate + ADP <=> Isopentenyladenosine-5'-diphosphate + Diphosphate
D-Glucarate <=> 2-Dehydro-3-deoxy-D-glucarate + H2O
2 GTP <=> 3',5'-Cyclic diGMP + 2 Diphosphate
5,6,7,8-Tetrahydromethanopterin + Formaldehyde <=> 5,10-Methylenetetrahydromethanopterin + H2O
5,10-Methylenetetrahydromethanopterin + NADP+ <=> 5,10-Methenyltetrahydromethanopterin + NADPH
Formylmethanofuran + H2O <=> Formate + Methanofuran
Isopentenyladenosine-5'-triphosphate + H2O <=> Isopentenyladenosine-5'-diphosphate + Orthophosphate
Isopentenyladenosine-5'-diphosphate + H2O <=> N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + Orthophosphate
trans-Zeatin riboside triphosphate + H2O <=> trans-Zeatin riboside diphosphate + Orthophosphate
trans-Zeatin riboside diphosphate + H2O <=> trans-Zeatin riboside monophosphate + Orthophosphate
trans-Zeatin riboside monophosphate <=> Dihydrozeatin riboside monophosphate
trans-Zeatin riboside <=> Dihydrozeatin riboside
N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + H2O <=> Isopentenyl adenosine + Orthophosphate
trans-Zeatin riboside monophosphate + H2O <=> trans-Zeatin riboside + Orthophosphate
Dihydrozeatin riboside monophosphate + H2O <=> Dihydrozeatin riboside + Orthophosphate
Isopentenyl adenosine + H2O <=> N6-(Delta2-Isopentenyl)-adenine + D-Ribose
trans-Zeatin riboside + H2O <=> Zeatin + D-Ribose
Dihydrozeatin riboside + H2O <=> Dihydrozeatin + D-Ribose
Zeatin + UDP-glucose <=> trans-Zeatin-7-beta-D-glucoside + UDP
Dihydrozeatin + UDP-glucose <=> Dihydrozeatin-O-glucoside + UDP
tRNA containing 6-isopentenyladenosine <=> cis-Prenyl-tRNA
cis-Prenyl-tRNA <=> cis-Zeatin riboside monophosphate
cis-Zeatin riboside monophosphate + H2O <=> cis-Zeatin riboside + Orthophosphate
cis-Zeatin riboside + H2O <=> cis-Zeatin + D-Ribose
Pinocembrin + 2-Oxoglutarate + Oxygen <=> Chrysin + Succinate + CO2 + H2O
Pinobanksin + 2-Oxoglutarate + Oxygen <=> Galangin + Succinate + CO2 + H2O
Nerol + NADP+ <=> cis-Citral + NADPH + H+
beta-Citronellol + NADP+ <=> (R)-(+)-Citronellal + NADPH + H+
(-)-Citronellol + NADP+ <=> (S)-(-)-Citronellal + NADPH + H+
Geranial + NAD+ + H2O <=> Geranic acid + NADH + H+
(R)-(+)-Citronellal + NAD+ + H2O <=> Citronellate + NADH + H+
Citronellate + CoA + ATP <=> Citronellyl-CoA + AMP + Diphosphate
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 7-Methyl-3-oxo-6-octenoyl-CoA + Acetate
7-Methyl-3-oxo-6-octenoyl-CoA + CoA <=> 5-Methylhex-4-enoyl-CoA + Acetyl-CoA
5-Methylhex-4-enoyl-CoA + FAD <=> (2E)-5-Methylhexa-2,4-dienoyl-CoA + FADH2
(2E)-5-Methylhexa-2,4-dienoyl-CoA + H2O <=> 3-Hydroxy-5-methylhex-4-enoyl-CoA
3-Hydroxy-5-methylhex-4-enoyl-CoA + NAD+ <=> 5-Methyl-3-oxo-4-hexenoyl-CoA + NADH + H+
5-Methyl-3-oxo-4-hexenoyl-CoA + CoA <=> 3-Methylcrotonyl-CoA + Acetyl-CoA
(S)-(-)-Citronellal + NAD+ + H2O <=> Citronellate + NADH + H+
Geranic acid + CoA <=> trans-Geranyl-CoA + H2O
trans-Geranyl-CoA <=> Geranoyl-CoA
cis-Citral <=> Geranial
2-Fluorobenzoate + NADH + H+ + Oxygen <=> 2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
2-Fluorobenzoate + NADH + H+ + Oxygen <=> 6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
Astaxanthin <=> Astaxanthin diester
Fluorobenzene + NADH + Oxygen + H+ <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+
Fluorobenzene + NADH + H+ + Oxygen <=> 1-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+
4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+ <=> 4-Fluorocatechol + NADH + H+
1-Fluorocyclohexadiene-cis,cis-1,2-diol <=> Catechol + Hydrofluoric acid
3-Fluorobenzoate + NADH + Oxygen + H+ <=> 3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
3-Fluorobenzoate + NADH + H+ + Oxygen <=> 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
4-Fluorobenzoate + NADH + H+ + Oxygen <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 3-Fluorocatechol + NADH + CO2 + H+
5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+
4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+
3-Fluorocatechol + Oxygen <=> 2-Fluoro-cis,cis-muconate
4-Fluorocatechol + Oxygen <=> 3-Fluoro-cis,cis-muconate
3-Fluoro-cis,cis-muconate <=> 4-Fluoromuconolactone
4-Fluorobenzoate + CoA + ATP <=> 4-Fluorobenzoyl-CoA + AMP + Diphosphate
4-Fluorobenzoyl-CoA + H2O <=> 4-Hydroxybenzoyl-CoA + Hydrofluoric acid
2-Fluoro-cis,cis-muconate <=> 5-Fluoromuconolactone
5-Fluoromuconolactone + H2O <=> 2-Maleylacetate + Hydrofluoric acid
4-Fluoromuconolactone + H2O <=> 2-Maleylacetate + Hydrofluoric acid
2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate <=> Catechol
6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate <=> 3-Fluorocatechol
Fructoselysine + ATP <=> Fructoselysine 6-phosphate + ADP
Fructoselysine 6-phosphate + H2O <=> L-Lysine + D-Glucose 6-phosphate
Isovitexin <=> Isovitexin 2''-O-arabinoside
Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + H2O <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + D-Glucuronate
Kaempferol-3-O-galactoside + UDP-glucose <=> Kaempferol 3-O-beta-D-glucosylgalactoside + UDP
Naringenin <=> 8-C-Glucosylnaringenin
8-C-Glucosylnaringenin <=> Vitexin
7-Dehydrocholesterol <=> 14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione
2,22,25-Trideoxyecdysone <=> 2,22-Dideoxyecdysone
2,22-Dideoxyecdysone <=> 2-Deoxyecdysone
2-Deoxyecdysone <=> Ecdysone
14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione <=> 2,22-Dideoxy-3-dehydroecdysone
14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione <=> 2,22,25-Trideoxyecdysone
2,22-Dideoxy-3-dehydroecdysone <=> 3-Dehydro-2-deoxyecdysone
3-Dehydro-2-deoxyecdysone <=> 3-Dehydroecdysone
3-Dehydroecdysone + NADH + H+ <=> 3-Epiecdysone + NAD+
3-Dehydroecdysone + NADH + H+ <=> Ecdysone + NAD+
Ecdysone <=> 26-Hydroxyecdysone
20-Hydroxyecdysone <=> 20,26-Dihydroxyecdysone
trans,trans-Farnesyl diphosphate + 2 H2O <=> (2E,6E)-Farnesol + 2 Orthophosphate
2-trans,6-trans-Farnesal + NAD+ + H2O <=> Farnesoic acid + NADH + H+
Farnesoic acid + S-Adenosyl-L-methionine <=> Methyl farnesoate + S-Adenosyl-L-homocysteine
Juvenile hormone III + H2O <=> Juvenile hormone III acid + Methanol
(10S)-Juvenile hormone III diol + H2O <=> (10S)-Juvenile hormone III acid diol + Methanol
Juvenile hormone III acid + S-Adenosyl-L-methionine <=> Juvenile hormone III + S-Adenosyl-L-homocysteine
Juvenile hormone III acid + H2O <=> (10S)-Juvenile hormone III acid diol
Juvenile hormone III + H2O <=> (10S)-Juvenile hormone III diol
(10S)-Juvenile hormone III diol + ATP <=> (10S)-Juvenile hormone III diol phosphate + ADP
Juvenile hormone III <=> 12-trans-Hydroxy juvenile hormone III
Octanoyl-[acp] + H2O <=> Acyl-carrier protein + Octanoic acid
Decanoyl-[acp] + H2O <=> Acyl-carrier protein + Decanoic acid
Tetradecanoyl-[acp] + H2O <=> Acyl-carrier protein + Tetradecanoic acid
Hexadecenoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + (9Z)-Hexadecenoic acid
Octadecanoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Octadecanoic acid
Indolylmethylthiohydroximate + UDP-glucose <=> Indolylmethyl-desulfoglucosinolate + UDP
Isochorismate + 2-Oxoglutarate <=> 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO2
2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate <=> (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + Pyruvate
Indolylmethyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucobrassicin + Adenosine 3',5'-bisphosphate
Indole-3-acetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O <=> Indolylmethylthiohydroximate + Pyruvate + Ammonia
3'-N-Debenzoyltaxol + Benzoyl-CoA <=> Paclitaxel + CoA
Baccatin III + beta-Phenylalanoyl-CoA <=> 3'-N-Debenzoyl-2'-deoxytaxol + CoA
Stearoyl-CoA + H2O <=> CoA + Octadecanoic acid
Eicosanoyl-CoA + H2O <=> CoA + Icosanoic acid
Oleoyl-CoA + H2O <=> CoA + (9Z)-Octadecenoic acid
Linoleoyl-CoA + H2O <=> CoA + Linoleate
(9Z,12Z,15Z)-Octadecatrienoyl-CoA + H2O <=> CoA + (9Z,12Z,15Z)-Octadecatrienoic acid
(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoyl-CoA + H2O <=> CoA + (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + H2O <=> CoA + (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid
gamma-Linolenoyl-CoA + H2O <=> CoA + (6Z,9Z,12Z)-Octadecatrienoic acid
8,11,14-Eicosatrienoyl-CoA + H2O <=> CoA + Dihomo-gamma-linolenate
Arachidonyl-CoA + H2O <=> CoA + Arachidonate
Docosanoyl-CoA + H2O <=> CoA + Docosanoic acid
Tetracosanoyl-CoA + H2O <=> CoA + Tetracosanoic acid
Icosenoyl-CoA + H2O <=> CoA + Icosenoic acid
Docosenoyl-CoA + H2O <=> CoA + Erucic acid
Tetracosenoyl-CoA + H2O <=> CoA + (15Z)-Tetracosenoic acid
(7Z,10Z,13Z,16Z,19Z)-Docosapentaenoyl-CoA + H2O <=> CoA + (7Z,10Z,13Z,16Z,19Z)-Docosapentaenoic acid
(11Z,14Z)-Icosadienoyl-CoA + H2O <=> CoA + Icosadienoic acid
(7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + H2O <=> CoA + Adrenic acid
(11Z,14Z,17Z)-Icosatrienoyl-CoA + H2O <=> CoA + Icosatrienoic acid
N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetyl-alpha-D-glucosamine 1-phosphate
1,5-Anhydro-D-mannitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+
D-Threonine <=> Glycine + Acetaldehyde
D-Allothreonine <=> Glycine + Acetaldehyde
L-Arginine + Pyruvate <=> 5-Guanidino-2-oxopentanoate + L-Alanine
2-Hydroxyglutarate + NAD+ <=> 2-Oxoglutarate + NADH + H+
Dimethylallyl diphosphate <=> Isoprene + Diphosphate
3-Phosphonopyruvate + H2O <=> Pyruvate + Orthophosphate
ATP + 2-Oxoglutarate + HCO3- <=> ADP + Orthophosphate + Oxalosuccinate
Chlorophyllide + Oxygen + NADPH + H+ <=> 7(1)-Hydroxychlorophyllide a + H2O + NADP+
7(1)-Hydroxychlorophyllide a + Oxygen + NADPH + H+ <=> Chlorophyllide b + 2 H2O + NADP+
Androstenedione + NADPH + H+ + Oxygen <=> Testololactone + NADP+ + H2O
17alpha-Hydroxyprogesterone + NADPH + H+ + Oxygen <=> Androstenedione + Acetate + NADP+ + H2O
Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H+
Betaine aldehyde + Oxygen + H2O <=> Betaine + Hydrogen peroxide
Choline + 2 Oxygen + H2O <=> Betaine + 2 Hydrogen peroxide
2-Oxoglutarate + Acetyl-CoA <=> trans-Homoaconitate + CoA
(-)-threo-Iso(homo)2-citrate + NAD+ <=> 2-Oxopimelate + CO2 + NADH + H+
(-)-threo-Iso(homo)3-citrate + NAD+ <=> 2-Oxosuberate + CO2 + NADH + H+
7-Mercaptoheptanoylthreonine + ATP <=> Coenzyme B + ADP
L-Seryl-tRNA(Sec) + Selenophosphoric acid <=> L-Selenocysteinyl-tRNA(Sec) + Orthophosphate
Capecitabine + H2O <=> 5'-Deoxy-5-fluorocytidine + 1-Pentanol + CO2
5'-Deoxy-5-fluorocytidine + H2O <=> 5'-Deoxy-5-fluorouridine + Ammonia
5'-Deoxy-5-fluorouridine + Orthophosphate <=> 5-FU + 5-Deoxyribose-1-phosphate
L-Seryl-tRNA(Sec) + ATP <=> O-Phosphoseryl-tRNA(Sec) + ADP
O-Phosphoseryl-tRNA(Sec) + Selenophosphoric acid + H2O <=> L-Selenocysteinyl-tRNA(Sec) + 2 Orthophosphate
5-FU + NADPH + H+ <=> 5,6-Dihydro-5-fluorouracil + NADP+
5,6-Dihydro-5-fluorouracil + H2O <=> alpha-Fluoro-beta-ureidopropionic acid
alpha-Fluoro-beta-ureidopropionic acid + H2O <=> alpha-Fluoro-beta-alanine + CO2 + Ammonia
5-FU + alpha-D-Ribose 1-phosphate <=> 5-Fluorouridine + Orthophosphate
5-FU + 2-Deoxy-D-ribose 1-phosphate <=> 5-Fluorodeoxyuridine + Orthophosphate
5-FU + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 5-Fluorouridine monophosphate + Diphosphate
5-Fluorouridine + ATP <=> 5-Fluorouridine monophosphate + ADP
5-Fluorodeoxyuridine + ATP <=> 5-Fluorodeoxyuridine monophosphate + ADP
Azathioprine <=> 6-Mercaptopurine + 1-Methyl-4-nitroimidazole
6-Mercaptopurine + 2 H2O + 2 Oxygen <=> 6-Thiourate + 2 Hydrogen peroxide
6-Mercaptopurine + S-Adenosyl-L-methionine <=> 6-Methylmercaptopurine + S-Adenosyl-L-homocysteine
6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate
6-Methylmercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + Diphosphate
6-Thioinosine-5'-monophosphate + S-Adenosyl-L-methionine <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + S-Adenosyl-L-homocysteine
6-Thioinosine-5'-monophosphate + NAD+ + H2O <=> 6-Thioxanthine 5'-monophosphate + NADH + H+
6-Thioinosine-5'-monophosphate + ATP <=> 6-Mercaptopurine ribonucleoside 5'-diphosphate + ADP
6-Mercaptopurine ribonucleoside 5'-diphosphate + ATP <=> 6-Mercaptopurine ribonucleoside triphosphate + ADP
6-Mercaptopurine ribonucleoside triphosphate + H2O <=> 6-Thioinosine-5'-monophosphate + Diphosphate
6-Thioxanthine 5'-monophosphate + ATP + L-Glutamine + H2O <=> 6-Thioguanosine monophosphate + AMP + Diphosphate + L-Glutamate
Thioguanine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioguanosine monophosphate + Diphosphate
6-Thioguanosine monophosphate + S-Adenosyl-L-methionine <=> 6-Methylthioguanosine monophosphate + S-Adenosyl-L-homocysteine
beta-D-Ribopyranose <=> beta-D-Ribofuranose
Acetyl-CoA + Isoniazid <=> CoA + N-Acetylisoniazid
N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid
Acetyl-CoA + Acetylhydrazine <=> CoA + N,N'-Diacetylhydrazine
Isoniazid + H2O <=> Isonicotinic acid + Hydrazine
Isonicotinic acid + Glycine <=> Isonicotinylglycine
Isoniazid + Pyruvate <=> Isoniazid pyruvate + H2O
Isoniazid + 2-Oxoglutarate <=> Isoniazid alpha-ketoglutaric acid + H2O
Irinotecan + H2O <=> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid
Irinotecan <=> APC
NPC + H2O <=> SN-38 + 4-Amino-1-piperidinecarboxylic acid
SN-38 + UDP-glucuronate <=> SN38 glucuronide + UDP
SN38 glucuronide + H2O <=> SN-38 + D-Glucuronate
UDP-glucuronate + Codeine <=> UDP + Codeine-6-glucuronide
Morphine + UDP-glucuronate <=> Morphine-3-glucuronide + UDP
Morphine + UDP-glucuronate <=> Morphine-6-glucuronide + UDP
Tamoxifen + Oxygen + NADPH + H+ <=> Tamoxifen N-oxide + NADP+ + H2O
Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O
Tamoxifen <=> N-Desmethyltamoxifen
Hydroxytamoxifen <=> Endoxifen
N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O
Tamoxifen + NADPH + Oxygen + H+ <=> alpha-Hydroxytamoxifen + NADP+ + H2O
N-Desmethyltamoxifen <=> N,N-Didesmethyltamoxifen
(13Z,16Z)-Docosadienoyl-CoA + H2O <=> CoA + (13Z,16Z)-Docosadienoic acid
N-Desmethyltamoxifen + NADPH + H+ + Oxygen <=> alpha-Hydroxy-N-desmethyltamoxifen + H2O + NADP+
Cyclophosphamide + NADPH + H+ + Oxygen <=> 4-Hydroxycyclophosphamide + NADP+ + H2O
Cyclophosphamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
4-Hydroxycyclophosphamide <=> 4-Ketocyclophosphamide
4-Hydroxycyclophosphamide <=> Aldophosphamide
Aldophosphamide <=> Phosphoramide mustard + Acrolein
Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O
Aldophosphamide + NADH + H+ <=> Alcophosphamide + NAD+
Aldophosphamide + NAD+ + H2O <=> Carboxyphosphamide + NADH + H+
Aldophosphamide + NADP+ + H2O <=> Carboxyphosphamide + NADPH + H+
Carboxyphosphamide <=> Nornitrogen mustard
Ifosfamide + NADPH + H+ + Oxygen <=> 4-Hydroxyifosfamide + NADP+ + H2O
Ifosfamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
Ifosfamide <=> 2-Dechloroethylifosfamide + Chloroacetaldehyde
4-Hydroxyifosfamide <=> Aldoifosfamide
Aldoifosfamide <=> Isophosphoramide mustard + Acrolein
Aldoifosfamide <=> Alcoifosfamide
4-Hydroxyifosfamide <=> 4-Ketoifosfamide
Aldoifosfamide <=> Carboxyifosfamide
Lidocaine <=> Monoethylglycinexylidide
Lidocaine + NADPH + Oxygen + H+ <=> 3-Hydroxylidocaine + NADP+ + H2O
Monoethylglycinexylidide + H2O <=> 2,6-Dimethylaniline + N-Ethylglycine
Monoethylglycinexylidide <=> Glycinexylidide
3-Hydroxylidocaine <=> 3-Hydroxymonoethylglycinexylidide
Monoethylglycinexylidide <=> 3-Hydroxymonoethylglycinexylidide
Glycinexylidide <=> 2,6-Dimethylaniline
Lidocaine + H2O <=> 2,6-Dimethylaniline + N,N-Diethylglycine
2,6-Dimethylaniline <=> 4-Hydroxy-2,6-dimethylaniline
2,6-Dimethylaniline <=> 2-Amino-3-methylbenzoate
Felbamate + NADPH + H+ + Oxygen <=> p-Hydroxyfelbamate + NADP+ + H2O
Felbamate + NADPH + H+ + Oxygen <=> 2-Hydroxyfelbamate + NADP+ + H2O
Felbamate + H2O <=> 2-Phenyl-1,3-propanediol monocarbamate + CO2 + Ammonia
2-Phenyl-1,3-propanediol monocarbamate + NAD+ <=> 3-Carbamoyl-2-phenylpropionaldehyde + NADH + H+
3-Carbamoyl-2-phenylpropionaldehyde + NAD+ + H2O <=> 3-Carbamoyl-2-phenylpropionic acid + NADH + H+
3-Carbamoyl-2-phenylpropionaldehyde <=> Atropaldehyde + CO2 + Ammonia
3-Carbamoyl-2-phenylpropionaldehyde <=> 4-Hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one
4-Hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one + NAD+ <=> 5-Phenyl-1,3-oxazinane-2,4-dione + NADH + H+
5-Phenyl-1,3-oxazinane-2,4-dione + H2O <=> 3-Carbamoyl-2-phenylpropionic acid
Carbamazepine + NADPH + H+ + Oxygen <=> Carbamazepine-10,11-epoxide + NADP+ + H2O
Carbamazepine + NADPH + H+ + Oxygen <=> 3-Hydroxycarbamazepine + NADP+ + H2O
Carbamazepine-10,11-epoxide + H2O <=> Dihydroxycarbazepine
3-Hydroxycarbamazepine <=> 2,3-Dihydroxycarbamazepine
2,3-Dihydroxycarbamazepine <=> Carbamazepine-o-quinone
Carbamazepine <=> 2-Hydroxycarbamazepine
2-Hydroxycarbamazepine <=> 2-Hydroxyiminostilbene
2-Hydroxyiminostilbene <=> 2H-Dibenz[b,f]azepin-2-one
2-Hydroxycarbamazepine <=> 2,3-Dihydroxycarbamazepine
Oxcarbazepine <=> 10-Hydroxycarbazepine
10-Hydroxycarbazepine <=> Dihydroxycarbazepine
7-Mercaptoheptanoic acid + L-Threonine + ATP <=> 7-Mercaptoheptanoylthreonine + ADP + Orthophosphate
Valproic acid <=> 2-n-Propyl-4-pentenoic acid
Valproic acid + NADPH + H+ + Oxygen <=> 4-Hydroxyvalproic acid + NADP+ + H2O
Valproic acid + NADPH + H+ + Oxygen <=> 5-Hydroxyvalproic acid + NADP+ + H2O
Valproic acid + NADPH + H+ + Oxygen <=> 3-Hydroxyvalproic acid + NADP+ + H2O
2-Oxosuberate <=> 7-Oxoheptanoic acid + CO2
2-n-Propyl-4-pentenoic acid <=> 2-Propyl-2,4-pentadienoic acid
4-Hydroxyvalproic acid <=> 2-n-Propyl-4-oxopentanoic acid
2-Oxoadipate + Acetyl-CoA + H2O <=> (R)-(Homo)2-citrate + CoA
2-Oxopimelate + Acetyl-CoA + H2O <=> (R)-(Homo)3-citrate + CoA
2-n-Propyl-4-oxopentanoic acid <=> 2-Propylsuccinic acid
5-Hydroxyvalproic acid <=> 2-Propylglutaric acid
3-Hydroxyvalproic acid <=> 3-Oxovalproic acid
Valproic acid <=> 2-n-Propyl-2-pentenoic acid
Valproic acid <=> 2-n-Propyl-3-pentenoic acid
2-n-Propyl-2-pentenoic acid <=> 3-Hydroxyvalproic acid
Methadone <=> 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine <=> 2-Ethyl-5-methyl-3,3-diphenyl-1-pyrroline
Levomethadyl acetate <=> L-alpha-Acetyl-N-normethadol
L-alpha-Acetyl-N-normethadol <=> L-alpha-Acetyl-N,N-dinormethadol
Citalopram <=> Demethylcitalopram
Citalopram <=> Citalopram N-oxide
Demethylcitalopram <=> Didemethylcitalopram
Citalopram + Oxygen + H2O <=> Citalopram aldehyde + Dimethylamine + Hydrogen peroxide
Demethylcitalopram + Oxygen + H2O <=> Citalopram aldehyde + Methylamine + Hydrogen peroxide
Didemethylcitalopram + H2O + Oxygen <=> Citalopram aldehyde + Ammonia + Hydrogen peroxide
Citalopram aldehyde + H2O + Oxygen <=> Citalopram propionic acid + Hydrogen peroxide
Trypanothione + H2O <=> Glutathione + Glutathionylspermidine
Homotrypanothione + H2O <=> Glutathione + Glutathionylaminopropylcadaverine
ATP + Glutathione + Spermine <=> ADP + Orthophosphate + Glutathionylspermine
ATP + Glutathione + Glutathionylspermine <=> ADP + Orthophosphate + Bis(glutathionyl)spermine
ATP + Glutathione + Aminopropylcadaverine <=> ADP + Orthophosphate + Glutathionylaminopropylcadaverine
ATP + Glutathione + Glutathionylaminopropylcadaverine <=> ADP + Orthophosphate + Homotrypanothione
Bis(glutathionyl)spermine + NADP+ <=> Bis(glutathionyl)spermine disulfide + NADPH + H+
Homotrypanothione + NADP+ <=> Homotrypanothione disulfide + NADPH + H+
Trypanothione + Dehydroascorbate <=> Trypanothione disulfide + Ascorbate
S-Adenosylmethioninamine + Cadaverine <=> 5'-Methylthioadenosine + Aminopropylcadaverine
Trypanothione + ROOH <=> Trypanothione disulfide + H2O + ROH
2'-Deoxyribonucleoside diphosphate + Trypanothione disulfide + H2O <=> Ribonucleoside diphosphate + Trypanothione
D-Galactosamine 6-phosphate + H2O <=> D-Tagatose 6-phosphate + Ammonia
N-Acetyl-D-galactosamine + Protein N(pi)-phospho-L-histidine <=> N-Acetyl-D-galactosamine 6-phosphate + Protein histidine
D-Galactosamine + Protein N(pi)-phospho-L-histidine <=> D-Galactosamine 6-phosphate + Protein histidine
N-D-Ribosylpurine + Orthophosphate <=> Purine + alpha-D-Ribose 1-phosphate
UDP-glucose + N6-Alkylaminopurine <=> UDP + N6-Alkylaminopurine-9-beta-D-glucoside
trans,trans-Farnesyl diphosphate <=> (E)-alpha-Bisabolene + Diphosphate
2 delta-Cadinene <=> Gossypol
1-Hydroxyalkyl-sn-glycerol <=> Aldehyde + Glycerol
trans,trans-Farnesyl diphosphate <=> Humulene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Nerolidol + Diphosphate
(S)-2,3-Epoxysqualene <=> Euphol
Euphol <=> Azadirachtin A
(S)-2,3-Epoxysqualene <=> Cucurbitacin E
Retinol + NADP+ <=> Retinal + NADPH + H+
11-cis-Retinol + NADP+ <=> 11-cis-Retinal + NADPH + H+
Palmitoyl-CoA + 11-cis-Retinol <=> CoA + 11-cis-Retinyl palmitate
9-cis-Retinol + NAD+ <=> 9-cis-Retinal + NADH + H+
9-cis-Retinol + NADP+ <=> 9-cis-Retinal + NADPH + H+
9-cis-Retinal + Oxygen + H2O <=> 9-cis-Retinoic acid + Hydrogen peroxide
9-cis-Retinal + NAD+ + H2O <=> 9-cis-Retinoic acid + NADH + H+
Phosphatidylcholine + Retinol <=> 2-Acyl-sn-glycero-3-phosphocholine + Retinyl ester
Retinyl ester + H2O <=> 11-cis-Retinol + Fatty acid
Palmitoylphosphatidylcholine + 11-cis-Retinol <=> 11-cis-Retinyl palmitate + 2-Acyl-sn-glycero-3-phosphocholine
Retinoate + NADPH + H+ + Oxygen <=> all-trans-5,6-Epoxyretinoic acid + NADP+ + H2O
Geranyl diphosphate <=> Nerol
Geranyl diphosphate <=> cis-Citral
Geranyl diphosphate <=> Car-3-ene + Diphosphate
Geranyl diphosphate + H2O <=> Geraniol + Diphosphate
Geranyl diphosphate <=> beta-Citronellol
Geranyl diphosphate <=> Geranial
Geranyl diphosphate <=> (R)-(+)-Citronellal
poly-cis-Polyprenyl diphosphate + Isopentenyl diphosphate <=> poly-cis-Polyprenyl diphosphate longer by one C5 unit + Diphosphate
ent-Kaurene <=> Stevioside
Levopimaradiene <=> Ginkgolide A
DNA 2,6-diamino-5-formamido-3,4-dihydro-4-oxopyrimidine <=> DNA containing guanine + H2O
Acyl phosphate + D-Glucose <=> Carboxylate + D-Glucose 6-phosphate
Acyl phosphate + D-Mannose <=> Carboxylate + D-Mannose 6-phosphate
Acyl phosphate + D-Fructose <=> Carboxylate + D-Fructose 6-phosphate
Acyl phosphate + D-Fructose <=> Carboxylate + D-Fructose 1-phosphate
1-Methylnicotinamide + Oxygen + H2O <=> N1-Methyl-2-pyridone-5-carboxamide + Hydrogen peroxide + H+
Xanthine + 2 S-Adenosyl-L-methionine <=> Theophylline + 2 S-Adenosyl-L-homocysteine
L-Leucine <=> 3-Methylbutanoic acid
L-Histidine + 3-Methylbutanoic acid <=> Dolichotheline
L-Histidine <=> Pilocarpine
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate <=> L-Pipecolate
L-Pipecolate <=> 1-Indolizidinone
1-Indolizidinone <=> Swainsonine
1-Indolizidinone <=> Slaframine
Cadaverine <=> Lupinine
Cadaverine <=> (-)-Sparteine
(-)-Sparteine <=> Cytisine
Cadaverine <=> Lupanine
Piperideine + trans-Cinnamate <=> (-)-Sedamine
Piperideine + trans-Cinnamate + Benzoyl-CoA <=> Lobelanine + CoA
Lobelanine <=> Lobeline
N-Methylpelletierine <=> Pseudopelletierine
Nicotinate <=> 3,6-Dihydronicotinic acid
1-Methylpyrrolinium <=> Cuscohygrine
1-Methylpyrrolinium <=> (-)-Hygrine
1-Methylpyrrolinium <=> Ecgonine methyl ester
Ecgonine methyl ester + Benzoyl-CoA <=> Cocaine + CoA
1-Methylpyrrolinium <=> Tropinone
Tropine + Phenyllactylglucose <=> Littorine + D-Glucose
Acetyl-CoA + Co(I) corrinoid protein + H+ <=> CO + Methyl-Co(III) corrinoid protein + CoA
Hyoscyamine aldehyde <=> L-Hyoscyamine
4-Coumarate <=> 3,4-Dihydroxybenzaldehyde
Tyramine + 3,4-Dihydroxybenzaldehyde <=> Norcraugsodine + H2O
Norbelladine + S-Adenosyl-L-methionine <=> 4'-O-Methylnorbelladine + S-Adenosyl-L-homocysteine
4'-O-Methylnorbelladine <=> Noroxopluviine
(4aR,10bS)-Normaritidine <=> Crinine
Norgalanthamine + S-Adenosyl-L-methionine <=> Galanthamine + S-Adenosyl-L-homocysteine
N-Demethylnarwedine + NADPH <=> Norgalanthamine + NADP+
3,4-Dihydroxy-L-phenylalanine <=> (-)-Salsolinol
Dopamine <=> Mescaline
Dopamine <=> Anhalamine
Anhalonidine + S-Adenosyl-L-methionine <=> Anhalonine + S-Adenosyl-L-homocysteine
Dopamine + 4-Hydroxydihydrocinnamaldehyde <=> (S)-Autumnaline
(S)-Autumnaline + NADPH + Oxygen + H+ <=> Isoandrocymbine + NADP+ + 2 H2O
Isoandrocymbine + S-Adenosyl-L-methionine <=> O-Methylandrocymbine + S-Adenosyl-L-homocysteine
O-Methylandrocymbine <=> N-Formyldemecolcine
N-Formyldemecolcine + H2O <=> Demecolcine + Formate
Demecolcine <=> Deacetylcolchicine
Deacetylcolchicine + Acetyl-CoA <=> Colchicine + CoA
(S)-Autumnaline <=> Floramultine
Floramultine + S-Adenosyl-L-methionine <=> Kreysigine + S-Adenosyl-L-homocysteine
(S)-Coclaurine <=> (S)-6-O-Methylnorlaudanosoline
(S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine <=> Tubocurarine
2 (S)-N-Methylcoclaurine <=> (+)-Tetrandrine
(S)-Reticuline <=> (S)-Isoboldine
Limonin + H2O <=> Limonoate A-ring-lactone
L-Phenylalanine <=> D-Cathinone
D-Cathinone <=> D-Cathine
D-Cathine + S-Adenosyl-L-methionine <=> (+)-(1S,2S)-Pseudoephedrine + S-Adenosyl-L-homocysteine
D-Cathinone <=> (-)-Norephedrine
(-)-Norephedrine + S-Adenosyl-L-methionine <=> Ephedrine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + Peptide 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide 2-[3-carboxy-3-(dimethylammonio)propyl]-L-histidine
S-Adenosyl-L-methionine + Peptide 2-[3-carboxy-3-(dimethylammonio)propyl]-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide diphthine
1,3-Dihydroxy-N-methylacridone <=> Melicopicine
1,3-Dihydroxy-N-methylacridone <=> Acronycine
1,3-Dihydroxy-N-methylacridone <=> Rutacridone
Anthranilate <=> 4-Hydroxy-2-quinolone
4-Hydroxy-2-quinolone <=> Platydesmine
Platydesmine <=> Dictamnine
Dictamnine <=> Skimmianine
Anthranilate + 1-Pyrroline <=> Peganine
N-Acetylanthranilate + L-Aspartate <=> Peganine
ATP + Psilocin <=> ADP + Psilocybin
Tryptamine <=> Physostigmine
Tryptamine <=> Harman
Tryptamine <=> Calligonine
Tryptamine <=> Harmaline
Harmaline <=> Harmine
Harmaline <=> Tetrahydroharmine
3-alpha(S)-Strictosidine <=> Strictosamide
Strictosamide <=> Pumiloside
Pumiloside <=> Deoxypumiloside
Deoxypumiloside <=> Camptothecin
Corynantheal <=> Cinchoninone
Cinchoninone + NADPH + H+ <=> Cinchonine + NADP+
Quinidinone + NADPH + H+ <=> Quinidine + NADP+
3-alpha(S)-Strictosidine <=> Strychnine
3-alpha(S)-Strictosidine <=> Corynantheal
Corynantheal <=> Quinidinone
Corynantheal <=> Cinchonamine
(6E)-8-Hydroxygeraniol + 2 NADP+ <=> (6E)-8-Oxogeranial + 2 NADPH + 2 H+
Secologanin <=> Gentiopicrin
Geraniol <=> beta-Skytanthine
Geraniol <=> Actinidine
5-Deoxy-D-glucuronate <=> 2-Deoxy-5-keto-D-gluconic acid
Cholest-5-ene-3beta,26-diol <=> Solasodine
16alpha,22,26-Trihydroxycholesterol <=> Tomatidine
16alpha,22,26-Trihydroxycholesterol <=> Solanidine
Octanoic acid <=> gamma-Coniceine
gamma-Coniceine + NADPH + H+ <=> Coniine + NADP+
Nitrile + Glutathione <=> Hydrogen cyanide + R-S-Glutathione
Sulfuric monoester + Glutathione <=> Sulfate + R-S-Glutathione
Dopamine <=> Anhalonidine
Phosphoramidate + D-Glucose <=> D-Glucose 1-phosphate + Ammonia
ADP + D-Glucose 1-phosphate <=> Orthophosphate + ADP-glucose
L-Tyrosyl-tRNA(Tyr) <=> [Thyroglobulin]-L-tyrosine
[Thyroglobulin]-L-tyrosine + Iodine <=> [Thyroglobulin]-3-iodo-L-tyrosine + Hydroiodic acid
[Thyroglobulin]-3-iodo-L-tyrosine + Iodine <=> [Thyroglobulin]-3,5-diiodo-L-tyrosine + Hydroiodic acid
[Thyroglobulin]-3,5-diiodo-L-tyrosine + [Thyroglobulin]-3-iodo-L-tyrosine + Hydrogen peroxide <=> Thyroglobulin triiodothyronine + Thyroglobulin dehydroalanine + 2 H2O
2 [Thyroglobulin]-3,5-diiodo-L-tyrosine + Hydrogen peroxide <=> [Thyroglobulin]-L-thyroxine + Thyroglobulin dehydroalanine + 2 H2O
Thyroglobulin triiodothyronine <=> Triiodothyronine
[Thyroglobulin]-L-thyroxine <=> Thyroxine
Arachidonate + Oxygen <=> Leukotriene A4 + H2O
Geranyl diphosphate + Isopentenyl diphosphate <=> 2-cis,6-trans-Farnesyl diphosphate + Diphosphate
(+)-Bornyl diphosphate + H2O <=> (+)-Borneol + Diphosphate
Acetyl-CoA + (-)-Menthol <=> CoA + (-)-Menthyl acetate
Acetyl-CoA + (+)-Neomenthol <=> CoA + Neomenthyl acetate
Acetyl-CoA + (+)-Borneol <=> CoA + Bornyl acetate
UDP-glucose + Sinapate <=> UDP + 4-O-beta-D-Glucosyl-sinapate
UDP-glucose + 4-Coumarate <=> UDP + p-Coumaroyl-D-glucose
Squalene <=> Hopane-29-acetate
L-Glucitol + NAD+ <=> L-Fructose + NADH + H+
S-Adenosyl-L-methionine + N-Methylserotonin <=> S-Adenosyl-L-homocysteine + Bufotenine
S-Adenosyl-L-methionine + 5-Hydroxyxanthotoxin <=> S-Adenosyl-L-homocysteine + Isopimpinellin
trans,trans-Farnesyl diphosphate <=> gamma-Humulene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Caryophyllene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Longifolene + Diphosphate
trans,trans-Farnesyl diphosphate + 2 H2O <=> Geosmin + Diphosphate + Acetone
D-Galactose + NAD+ <=> D-Galactono-1,5-lactone + NADH + H+
trans,trans-Farnesyl diphosphate <=> Germacrene B + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Selinene + Diphosphate
S-Adenosyl-L-methionine + L-Tryptophan <=> S-Adenosyl-L-homocysteine + L-2-Methyltryptophan
D-Fructose 1-phosphate + H2O <=> D-Fructose + Orthophosphate
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
[Protein]-N6-[(R)-dihydrolipoyl]-L-lysine + NAD+ <=> Protein N6-(lipoyl)lysine + NADH + H+
AMP + Sulfite + FAD <=> Adenylyl sulfate + FADH2
(R)-Lactate + N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetylmuramic acid 6-phosphate + H2O
Choline + NAD+ <=> Betaine aldehyde + NADH + H+
Choline + NADP+ <=> Betaine aldehyde + NADPH + H+
N-Acetylmuramate + Protein N(pi)-phospho-L-histidine <=> N-Acetylmuramic acid 6-phosphate + Protein histidine
Cinchonidinone <=> Cinchoninone
Cinchoninone + NADPH + H+ <=> Cinchonidine + NADP+
Quinidinone + NADPH + H+ <=> Quinine + NADP+
Cinchonidinone + NADPH + H+ <=> Cinchonidine + NADP+
Corynantheal <=> Cinchonidinone
L-Aspartate 4-semialdehyde + 6-Deoxy-5-ketofructose 1-phosphate <=> 2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + Hydroxypyruvaldehyde phosphate
2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + H2O + NAD+ <=> 3-Dehydroquinate + Ammonia + NADH + H+
2-Dehydro-3-deoxy-D-gluconate <=> D-Glyceraldehyde + Pyruvate
D-Glycerate + ATP <=> 2-Phospho-D-glycerate + ADP
D-Threitol + NADP+ <=> D-Erythrulose + NADPH + H+
CTP + Riboflavin <=> CDP + FMN
Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Fructose 6-phosphate
O-Phosphoseryl-tRNA(Cys) + Hydrogen sulfide <=> L-Cysteinyl-tRNA(Cys) + Orthophosphate
Parathion <=> Paraoxon
Chlorophyll a + 2 H+ <=> Pheophytin a + Magnesium cation
Chlorophyll a <=> Chlorophyll b
Futalosine + H2O <=> Dehypoxanthine futalosine + Hypoxanthine
Dehypoxanthine futalosine + S-Adenosyl-L-methionine <=> Cyclic dehypoxanthine futalosine + 5'-Deoxyadenosine + L-Methionine
Cyclic dehypoxanthine futalosine <=> 1,4-Dihydroxy-6-naphthoate
3-Sulfopyruvate + NADH + H+ <=> 3-Sulfolactate + NAD+
dTDP-2,6-dideoxy-L-glycero-hex-2-enos-4-ulose <=> dTDP-3,4-dioxo-2,6-dideoxy-L-glucose
1,4-Dihydroxy-6-naphthoate <=> Menaquinone
dTDP-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
N-Acetyl-4-O-acetylneuraminate + H2O <=> N-Acetylneuraminate + Acetate
N-Acetyl-9-O-acetylneuraminate + H2O <=> N-Acetylneuraminate + Acetate
S-Palmitoylprotein + H2O <=> Hexadecanoic acid + [Protein]-L-cysteine
3D-3,5/4-Trihydroxycyclohexane-1,2-dione + H2O <=> 5-Deoxy-D-glucuronate
Tryptamine + Oxygen + NADPH <=> N-Hydroxyl-tryptamine + H2O + NADP+
N-Hydroxyl-tryptamine <=> Indole-3-acetaldehyde oxime
Indole-3-acetaldehyde oxime <=> Indole-3-acetaldehyde
Indole-3-acetaldehyde oxime + NADPH + Oxygen + H+ <=> Indole-3-acetaldoxime N-oxide + NADP+ + H2O
Indole-3-acetaldoxime N-oxide + L-Cysteine <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O
Indole <=> Indole-3-acetate
5-Hydroxymethyluracil + 2-Oxoglutarate + Oxygen <=> Uracil 5-carbaldehyde + Succinate + CO2 + H2O
Uracil 5-carbaldehyde + 2-Oxoglutarate + Oxygen <=> Uracil 5-carboxylate + Succinate + CO2
1,4-beta-D-Mannan + H2O <=> 1,4-beta-D-Mannooligosaccharide + 1,4-beta-D-Mannan
beta-D-Mannoside + H2O <=> ROH + D-Mannose
1,4-beta-D-Mannooligosaccharide + H2O <=> D-Mannose + 1,4-beta-D-Mannooligosaccharide
UDP-glucuronate + H2O <=> UDP + D-Glucuronate
2 Raffinose <=> Isolychnose + Sucrose
D-Glucose 6-phosphate <=> 2-Deoxy-scyllo-inosose + Orthophosphate
L-Methionine + 2-Oxo acid <=> 4-Methylthio-2-oxobutanoic acid + L-Amino acid
4-Methylthio-2-oxobutanoic acid + Acetyl-CoA + H2O <=> 2-(2'-Methylthio)ethylmalic acid + CoA
2-(2'-Methylthio)ethylmalic acid <=> 3-(2'-Methylthio)ethylmalic acid
3-(2'-Methylthio)ethylmalic acid + NAD+ <=> 2-Oxo-5-methylthiopentanoic acid + CO2 + NADH + H+
2-Oxo-5-methylthiopentanoic acid + L-Amino acid <=> Homomethionine + 2-Oxo acid
2-Oxo-5-methylthiopentanoic acid + Acetyl-CoA + H2O <=> 2-(3'-Methylthio)propylmalic acid + CoA
2-(3'-Methylthio)propylmalic acid <=> 3-(3'-Methylthio)propylmalic acid
3-(3'-Methylthio)propylmalic acid + NAD+ <=> 2-Oxo-6-methylthiohexanoic acid + CO2 + NADH + H+
2-Oxo-6-methylthiohexanoic acid + L-Amino acid <=> Dihomomethionine + 2-Oxo acid
2-Oxo-6-methylthiohexanoic acid + Acetyl-CoA + H2O <=> 2-(4'-Methylthio)butylmalic acid + CoA
2-(4'-Methylthio)butylmalic acid <=> 3-(4'-Methylthio)butylmalic acid
3-(4'-Methylthio)butylmalic acid + NAD+ <=> 2-Oxo-7-methylthioheptanoic acid + CO2 + NADH + H+
2-Oxo-7-methylthioheptanoic acid + L-Amino acid <=> Trihomomethionine + 2-Oxo acid
2-Oxo-7-methylthioheptanoic acid + Acetyl-CoA + H2O <=> 2-(5'-Methylthio)pentylmalic acid + CoA
L-Cystathionine <=> L-Cysteine + 2-Aminobut-2-enoate
L-Homocysteine <=> Hydrogen sulfide + 2-Aminobut-2-enoate
2-(5'-Methylthio)pentylmalic acid <=> 3-(5'-Methylthio)pentylmalic acid
L-Methionine <=> Methanethiol + 2-Aminobut-2-enoate
3-(5'-Methylthio)pentylmalic acid + NAD+ <=> 2-Oxo-8-methylthiooctanoic acid + CO2 + NADH + H+
2-Aminobut-2-enoate + H2O <=> 2-Oxobutanoate + Ammonia
2-Oxo-8-methylthiooctanoic acid + L-Amino acid <=> Tetrahomomethionine + 2-Oxo acid
D-Glucose 1-phosphate <=> D-Glucose 6-phosphate
2-Oxo-8-methylthiooctanoic acid + Acetyl-CoA + H2O <=> 2-(6'-Methylthio)hexylmalic acid + CoA
2-(6'-Methylthio)hexylmalic acid <=> 3-(6'-Methylthio)hexylmalic acid
3-(6'-Methylthio)hexylmalic acid + NAD+ <=> 2-Oxo-9-methylthiononanoic acid + CO2 + NADH + H+
2-Oxo-9-methylthiononanoic acid + L-Amino acid <=> Pentahomomethionine + 2-Oxo acid
2-Oxo-9-methylthiononanoic acid + Acetyl-CoA + H2O <=> 2-(7'-Methylthio)heptylmalic acid + CoA
2-(7'-Methylthio)heptylmalic acid <=> 3-(7'-Methylthio)heptylmalic acid
3-(7'-Methylthio)heptylmalic acid + NAD+ <=> 2-Oxo-10-methylthiodecanoic acid + CO2 + NADH + H+
2-Oxo-10-methylthiodecanoic acid + L-Amino acid <=> Hexahomomethionine + 2-Oxo acid
Pyruvate + 2-Oxobutanoate <=> (S)-2-Aceto-2-hydroxybutanoate + CO2
L-Aspartate 4-semialdehyde + Glycerone phosphate <=> 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O
D-Fructose + NADP+ <=> 5-Dehydro-D-fructose + NADPH + H+
(Z)-Phenylacetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
S-(Phenylacetothiohydroximoyl)-L-cysteine + H2O <=> Phenylacetothiohydroximate + Pyruvate + Ammonia
L-Homophenylalanine + 2 Oxygen + 2 NADPH + 2 H+ <=> 3-Phenylpropionaldoxim + 2 NADP+ + CO2 + 3 H2O
sn-Glycerol 3-phosphate + Ubiquinone <=> Glycerone phosphate + Ubiquinol
DL-Glycerol 1-phosphate + H2O <=> Glycerol + Orthophosphate
(Z)-4-Hydroxyphenylacetaldehyde oxime + Oxygen + NADPH + L-Cysteine + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + H2O <=> p-Hydroxyphenylacetothiohydroximate + Pyruvate + Ammonia
p-Hydroxyphenylacetothiohydroximate + UDP-glucose <=> p-Hydroxybenzyldesulphoglucosinolate + UDP
p-Hydroxybenzyldesulphoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Sinalbin + Adenosine 3',5'-bisphosphate
L-Leucine + 2 Oxygen + 2 NADPH + 2 H+ <=> 3-Methylbutyraldehyde oxime + 3 H2O + 2 NADP+ + CO2
S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + H2O <=> 4-Methylthiobutylthiohydroximate + Pyruvate + Ammonia
4-Methylthiobutylthiohydroximate + UDP-glucose <=> 3-Methylthiopropyl-desulfoglucosinolate + UDP
3-Methylthiopropyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucoiberverin + Adenosine 3',5'-bisphosphate
4-Methylthiobutyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucoerucin + Adenosine 3',5'-bisphosphate
ADP + Sucrose <=> ADP-glucose + D-Fructose
S-Sulfanylglutathione + Oxygen + H2O <=> Glutathione + Sulfite
Amino acid + 2-Oxo acid <=> Amino acid + 2-Oxo acid
2-Oxo acid + Acetyl-CoA + H2O <=> 2-Alkylmalic acid + CoA
2-Alkylmalic acid <=> 3-Alkylmalic acid
3-Alkylmalic acid <=> Aliphatic oxo acid + CO2
Aliphatic oxo acid + Amino acid <=> Homoamino acid + 2-Oxo acid
Amino acid + 2 Oxygen + 2 NADPH + 2 H+ <=> Aldoxime + 2 NADP+ + 3 H2O + CO2
Aldoxime + NADPH + Oxygen + L-Cysteine + H+ <=> S-Alkyl-thiohydroximate + NADP+ + 2 H2O
S-Alkyl-thiohydroximate + H2O <=> Thiohydroximic acid + Pyruvate + Ammonia
Thiohydroximic acid + UDP-glucose <=> desulfo-Glucosinolate + UDP
desulfo-Glucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucosinolate + Adenosine 3',5'-bisphosphate
L-Phenylalanine <=> L-Homophenylalanine
trans,trans-Farnesyl diphosphate <=> (+)-Valencene + Diphosphate
GDP-D-mannuronate + (beta-D-Mannuronate)n <=> (beta-D-Mannuronate)n + GDP
(beta-D-Mannuronate)n <=> (Alginate)n
Pectate <=> Oligosaccharide with 4-deoxy-alpha-D-gluc-4-enuronosyl group + Pectate
trans,trans-Farnesyl diphosphate <=> beta-Farnesene + Diphosphate
trans,trans-Farnesyl diphosphate <=> alpha-Farnesene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (2E,6E)-Farnesol + Diphosphate
Dehydroalanine + H2O <=> Pyruvate + Ammonia
Dehydroalanine + 3'-Phosphoadenylyl sulfate <=> L-Cysteate + Adenosine 3',5'-bisphosphate
tRNA uridine + [Enzyme]-S-sulfanylcysteine + ATP <=> tRNA containing 2-thiouridine + [Enzyme]-cysteine + AMP + Diphosphate
tRNA containing 5-carboxymethylaminomethyl-2-thiouridine + Oxygen + H2O <=> tRNA containing 5-(aminomethyl)-2-thiouridine + Glyoxylate + Hydrogen peroxide
UDP-4-dehydro-6-deoxy-D-glucose <=> UDP-4-keto-rhamnose
UDP-4-keto-rhamnose + NADPH + H+ <=> UDP-L-rhamnose + NADP+
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate <=> UDP-N-acetyl-D-galactosaminuronic acid
4-N-(N-Acetyl-D-glucosaminyl)-protein + H2O <=> N-Acetyl-beta-D-glucosaminylamine + Peptide L-aspartate
CDP-4-dehydro-3,6-dideoxy-D-glucose <=> CDP-4-dehydro-3,6-dideoxy-D-glucose epimer
CDP-4-dehydro-3,6-dideoxy-D-glucose epimer + NADH + H+ <=> CDP-ascarylose + NAD+
CDP-4-dehydro-3,6-dideoxy-D-glucose epimer + NADPH + H+ <=> CDP-ascarylose + NADP+
CDP-4-dehydro-3,6-dideoxy-D-glucose + NADPH + H+ <=> CDP-abequose + NADP+
Acyl-CoA + Tropine <=> CoA + O-Acyltropine
Acyl-CoA + Pseudotropine <=> CoA + O-Acylpseudotropine
Putrescine + Pyruvate <=> 4-Aminobutyraldehyde + L-Alanine
Chitosan(n+1) + H2O <=> Chitosan(n) + D-Glucosamine
Cobalt-factor III <=> Cobalt-precorrin 3
(24S)-Cholest-5-ene-3beta,7alpha,24-triol + NAD+ <=> 7alpha,24-Dihydroxy-4-cholesten-3-one + NADH + H+
Cholest-5-ene-3beta,7alpha,25-triol + NAD+ <=> 7alpha,25-Dihydroxy-4-cholesten-3-one + NADH + H+
7alpha,27-Dihydroxycholesterol + NAD+ <=> 7alpha,26-Dihydroxy-4-cholesten-3-one + NADH + H+
3beta-Hydroxy-5-cholestenoate + Oxygen + NADPH + H+ <=> 3beta,7alpha-Dihydroxy-5-cholestenoate + NADP+ + H2O
3beta,7alpha-Dihydroxy-5-cholestenoate + NAD+ <=> 7alpha-Hydroxy-3-oxo-4-cholestenoate + NADH + H+
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + ATP + CoA <=> (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + Diphosphate
(25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA <=> (25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA
3alpha,7alpha-Dihydroxy-5beta-cholestanate + ATP + CoA <=> (25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + AMP + Diphosphate
(25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA <=> (25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
Chenodeoxycholoyl-CoA + Glycine <=> Glycochenodeoxycholate + CoA
Chenodeoxycholoyl-CoA + Taurine <=> Taurochenodeoxycholate + CoA
trans,trans-Farnesyl diphosphate <=> 2-cis,6-trans-Farnesyl diphosphate
all-trans-Nonaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Decaprenyl diphosphate + Diphosphate
trans,trans,cis-Geranylgeranyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Pentaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Pentaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Hexaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Heptaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Heptaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Octaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Octaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Nonaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Nonaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Decaprenyl diphosphate + Diphosphate
Geranylgeranyl diphosphate + NADPH + H+ <=> Dihydrogeranylgeranyl diphosphate + NADP+
Dihydrogeranylgeranyl diphosphate + NADPH + H+ <=> Tetrahydrogeranylgeranyl diphosphate + NADP+
Tetrahydrogeranylgeranyl diphosphate + NADPH + H+ <=> Phytyl diphosphate + NADP+
Hydroxylamine + 2 Ubiquinone + H2O <=> Nitrite + 2 Ubiquinol
3alpha,7alpha,26-Trihydroxy-5beta-cholestane <=> 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al
3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al
2 2-Aminophenol + Oxygen <=> 2 6-Iminocyclohexa-2,4-dienone + 2 H2O
6-Hydroxynicotinate + NADH + Oxygen + H+ <=> 2,5-Dihydroxypyridine + NAD+ + CO2 + H2O
Thymine dimer <=> Two thymine residues (in DNA)
(R)-3-(4-Hydroxyphenyl)lactate <=> 4-Coumarate + H2O
2-Polyprenylphenol + NADPH + H+ + Oxygen <=> 2-Polyprenyl-6-hydroxyphenol + NADP+ + H2O
2-Polyprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Polyprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine
4-Hydroxy-3-polyprenylbenzoate + Oxygen <=> 3,4-Dihydroxy-5-polyprenylbenzoate + H2O
3,4-Dihydroxy-5-polyprenylbenzoate + S-Adenosyl-L-methionine <=> 3-Methoxy-4-hydroxy-5-polyprenylbenzoate + S-Adenosyl-L-homocysteine
3-Methoxy-4-hydroxy-5-polyprenylbenzoate <=> 2-Polyprenyl-6-methoxyphenol + CO2
Homogentisate + all-trans-Nonaprenyl diphosphate <=> 2-Methyl-6-solanyl-1,4-benzoquinol + Diphosphate + CO2
(S)-Reticuline + S-Adenosyl-L-methionine <=> Laudanine + S-Adenosyl-L-homocysteine
(R)-Reticuline + S-Adenosyl-L-methionine <=> Laudanine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + (S)-Canadine <=> S-Adenosyl-L-homocysteine + (S)-N-Methylcanadine
(S)-Corytuberine + S-Adenosyl-L-methionine <=> Magnoflorine + S-Adenosyl-L-homocysteine
Amino acid <=> Homoamino acid
S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + 3'-Hydroxy-N-methyl-(S)-coclaurine
Tetrahydropalmatine + 2 Oxygen + H+ <=> Palmatine + 2 Hydrogen peroxide
1-(4-Hydroxyphenyl)-1-decene-3,5-dione <=> 5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone
1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone
1-Dehydro-[6]-gingerdione <=> [6]-Gingerol
1-(4-Hydroxyphenyl)-1-decene-3,5-dione <=> 1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione
5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone
1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione + S-Adenosyl-L-methionine <=> 1-Dehydro-[6]-gingerdione + S-Adenosyl-L-homocysteine
1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone + S-Adenosyl-L-methionine <=> [6]-Gingerol + S-Adenosyl-L-homocysteine
Feruloyl-CoA + Malonyl-CoA <=> Feruloyl-diketide-CoA + CoA + CO2
Bisdemethoxycurcumin <=> Demethoxycurcumin
Demethoxycurcumin <=> Curcumin
Curcumin + UDP-glucose <=> Curcumin monoglucoside + UDP
Curcumin monoglucoside + UDP-glucose <=> Curcumin diglucoside + UDP
2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + UDP-glucose <=> cyclo-Dopa 5-O-glucoside + UDP
cyclo-Dopa 5-O-glucoside + UDP-glucuronate <=> cyclo-Dopa-glucuronylglucoside + UDP
cyclo-Dopa-glucuronylglucoside + Betalamic acid <=> Amaranthin + H2O
Amaranthin + 1-O-Feruloyl-beta-D-glucose <=> Celosianin II + D-Glucose
cyclo-Dopa 5-O-glucoside + Betalamic acid <=> Betanin + H2O
2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + Betalamic acid <=> Betanidin + H2O
Betanidin + UDP-glucose <=> Betanin + UDP
Betanin + 1-O-Feruloyl-beta-D-glucose <=> Lampranthin II + D-Glucose
Betanin + UDP-glucuronate <=> Amaranthin + UDP
L-Tyrosine + Betalamic acid <=> Portulacaxanthin II + H2O
Portulacaxanthin II + Oxygen + Dopaxanthin <=> Dopaxanthin + H2O + Dopaxanthin quinone
3,4-Dihydroxy-L-phenylalanine + Betalamic acid <=> Dopaxanthin + H2O
2 Dopaxanthin + Oxygen <=> 2 Dopaxanthin quinone + 2 H2O
Dopaxanthin quinone <=> Betanidin
Betanidin + UDP-glucose <=> Gomphrenin-I + UDP
3-Methoxytyramine + Betalamic acid <=> 3-Methoxytyramine-betaxanthin + H2O
2 Dopamine + Oxygen <=> 2 Dopamine quinone + 2 H2O
Dopamine quinone <=> 2-Descarboxy-cyclo-dopa
2-Descarboxy-cyclo-dopa + Betalamic acid <=> 2-Descarboxy-betanidin + H2O
Dopamine + Betalamic acid <=> Miraxanthin-V + H2O
4,5-seco-Dopa <=> Betalamic acid + H2O
Benzoate + NADPH + Oxygen <=> Salicylate + NADP+ + H2O
UDP-glucose + Ferulate <=> 1-O-Feruloyl-beta-D-glucose + UDP
7-Oxateasterone <=> 7-Oxatyphasterol
1-Guanidino-1-deoxy-scyllo-inositol <=> 1D-1-Guanidino-1-deoxy-3-dehydro-scyllo-inositol
ATP + 1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol <=> ADP + N1-Amidinostreptamine 6-phosphate
3,4-Dihydroxy-L-phenylalanine + NADH + H+ <=> 3,4-Dihydroxyphenylpropanoate + NAD+ + Ammonia
3,4-Dihydroxyphenylpropanoate <=> (R)-3-(3,4-Dihydroxyphenyl)lactate
Dopaquinone + L-Cysteine <=> Cysteinyldopa
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine + H2O <=> UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + D-Alanine
UDP-N-acetyl-alpha-D-glucosamine + di-trans,poly-cis-Undecaprenyl phosphate <=> N-Acetyl-D-glucosaminyldiphosphoundecaprenol + UMP
alpha-D-Galactosyl-diphosphoundecaprenol + dTDP-L-rhamnose <=> alpha-L-Rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol + dTDP
alpha-L-Rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol + GDP-mannose <=> alpha-D-Mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol + GDP
Limonoate A-ring-lactone + UDP-glucose <=> Glucosyl-limonin + UDP
Phosphonoacetaldehyde + NADPH + H+ <=> 2-Hydroxyethylphosphonate + NADP+
(S)-2-Hydroxypropylphosphonate + Hydrogen peroxide <=> Fosfomycin + 2 H2O
2-Hydroxyethylphosphonate + Oxygen <=> Hydroxymethylphosphonate + Formate
Hydroxymethylphosphonate <=> Formylphosphonate
Formylphosphonate <=> Phosphonoformate
Phosphonoformate + CTP <=> Phosphonoformyl-CMP + Diphosphate
1-Carboxyvinyl carboxyphosphonate <=> Carboxyphosphonopyruvate
Carboxyphosphonopyruvate <=> 3-(Hydrohydroxyphosphoryl)pyruvate + CO2
3-(Hydrohydroxyphosphoryl)pyruvate + Acetyl-CoA + H2O <=> 2-Phosphinomethylmalate + CoA
Demethylphosphinothricin + Acetyl-CoA <=> N-Acetyldemethylphosphinothricin + CoA
N-Acetyldemethylphosphinothricin + 2 L-Alanine + 3 ATP + H2O <=> N-Acetyldemethylphosphinothricin tripeptide + 3 AMP + 3 Diphosphate
N-Acetylphosphinothricin + H2O <=> L-Phosphinothricin + Acetate
N-Acetylbialaphos + H2O <=> Bialaphos + Acetate
Deamino-alpha-keto-demethylphosphinothricin <=> Demethylphosphinothricin
2-Dehydro-L-idonate + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+
5-Dehydro-D-gluconate + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+
L-Idonate + NADP+ <=> 2-Dehydro-L-idonate + NADPH + H+
(R)-2-(Phosphonomethyl)malate <=> 2-Oxo-4-phosphonobutanoate
2-Oxo-4-phosphonobutanoate <=> FR 900098
Phosphonoacetaldehyde <=> Rhizocticin B
Phosphonoacetaldehyde <=> Rhizocticin A
Phosphonoacetaldehyde <=> Rhizocticin C
Phosphonoacetaldehyde <=> Rhizocticin D
Phosphonoformyl-CMP + 3-Phospho-D-glycerate <=> 1-Carboxyvinyl carboxyphosphonate + CMP + Orthophosphate
3-Phosphinomethylmalate <=> Deamino-alpha-keto-demethylphosphinothricin
8'-apo-beta-Carotenol + Oxygen <=> 14'-apo-beta-Carotenal + 7-Hydroxy-6-methylhepta-3,5-dienal
2-Deoxy-scyllo-inosose + L-Glutamine <=> 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate
3-Amino-2,3-dideoxy-scyllo-inosose + L-Glutamine <=> 2-Deoxystreptamine + 2-Oxoglutaramate
2-Deoxy-scyllo-inosamine + NAD+ <=> 3-Amino-2,3-dideoxy-scyllo-inosose + NADH + H+
2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine <=> 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine
UDP-N-acetyl-alpha-D-glucosamine + 2-Deoxystreptamine <=> UDP + 2'-N-Acetylparomamine
2'-N-Acetylparomamine + H2O <=> Paromamine + Acetate
Paromamine + Oxygen <=> 6'-Dehydro-6'-oxoparomamine + Hydrogen peroxide
Neamine + 2-Oxoglutarate <=> 6'-Dehydro-6'-oxoparomamine + L-Glutamate
5-Phospho-alpha-D-ribose 1-diphosphate + Neamine <=> Diphosphate + 5''-Phosphoribostamycin
5''-Phosphoribostamycin + H2O <=> Ribostamycin + Orthophosphate
UDP-N-acetyl-alpha-D-glucosamine + Ribostamycin <=> UDP + 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C
2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C + H2O <=> 6'''-Deamino-6'''-hydroxyneomycin C + Acetate
6'''-Deamino-6'''-hydroxyneomycin C + Oxygen <=> 6'''-Deamino-6'''-oxoneomycin C + Hydrogen peroxide
Neomycin C + 2-Oxoglutarate <=> 6'''-Deamino-6'''-oxoneomycin C + L-Glutamate
Neomycin C <=> Neomycin B
ATP + L-Glutamate + Acyl-carrier protein <=> ADP + Orthophosphate + gamma-L-Glutamyl-[acp]
ATP + L-Glutamate + 4-Aminobutyryl-[acp] <=> ADP + Orthophosphate + 4-(gamma-L-Glutamylamino)butanoyl-[acp]
gamma-L-Glutamyl-[acp] <=> 4-Aminobutyryl-[acp] + CO2
4-(gamma-L-Glutamylamino)butanoyl-[acp] + Reduced FMN + Oxygen <=> 4-(gamma-L-Glutamylamino)-(2S)-2-hydroxybutanoyl-[acp] + FMN + H2O
4-(gamma-L-Glutamylamino)-(2S)-2-hydroxybutanoyl-[acp] + Ribostamycin <=> Acyl-carrier protein + gamma-L-Glutamyl-butirosin B
gamma-L-Glutamyl-butirosin B <=> Butirosin B + 5-Oxoproline
Butirosin B <=> Butirosin A
7(1)-Hydroxychlorophyllide a + NAD+ <=> Chlorophyllide b + NADH + H+
7(1)-Hydroxychlorophyllide a + NADP+ <=> Chlorophyllide b + NADPH + H+
3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD+ <=> Momilactone A + NADH + H+
3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NADP+ <=> Momilactone A + NADPH + H+
1,6-Dihydrocarveol + NAD+ <=> Dihydrocarvone + NADH + H+
p-Menth-8-ene-1,2-diol + NAD+ <=> 1-Hydroxy-p-menth-8-en-2-one + NADH + H+
2 3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 2 3-(3,4-Dihydroxyphenyl)pyruvate + 2 Ammonia
ATP + HCO3- + Butanoyl-CoA + H+ <=> ADP + Orthophosphate + (2S)-Ethylmalonyl-CoA
(-)-Menthone + NADPH + H+ + Oxygen <=> (4R,7S)-7-Isopropyl-4-methyloxepan-2-one + NADP+ + H2O
L-Fucose + NAD+ <=> L-Fucono-1,5-lactone + NADH + H+
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose <=> dTDP-3-oxo-2,6-dideoxy-D-glucose
dTDP-3-oxo-2,6-dideoxy-D-glucose <=> dTDP-2,6-dideoxy-D-kanosamine
dTDP-2,6-dideoxy-D-kanosamine <=> dTDP-D-angolosamine
dTDP-4-oxo-2,3,6-trideoxy-D-glucose + L-Glutamate <=> dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose + 2-Oxoglutarate
dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-forosamine + 2 S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose
dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose
dTDP-L-rhamnose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-glucose + NADPH + H+
Malonyl-[acyl-carrier protein] + Biotinyl-[protein] <=> Acetyl-[acyl-carrier protein] + Carboxybiotinyl-[protein]
Carbamoyl phosphate + N2-Succinyl-L-ornithine <=> Orthophosphate + N-Succinyl-L-citrulline
Acetyl-CoA + L-Phosphinothricin <=> CoA + N-Acetylphosphinothricin
Butyryl-[acp] + S-Adenosyl-L-methionine <=> Acyl-carrier protein + 5'-Methylthioadenosine + N-Butyryl-L-homoserine lactone
Acyl-[acyl-carrier protein] + S-Adenosyl-L-methionine <=> Acyl-carrier protein + 5'-Methylthioadenosine + N-Acyl-L-homoserine lactone
Cholesterol + Sulfate <=> Cholesterol sulfate + H2O
Pregnenolone + Sulfate <=> 3beta-Hydroxypregn-5-en-20-one sulfate + H2O
Pregnenolone + NADPH + H+ + Oxygen <=> 7alpha-Hydroxypregnenolone + NADP+ + H2O
Acetyl-[acyl-carrier protein] + Malonate <=> Malonyl-[acyl-carrier protein] + Acetate
11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H+
ADP-glucose + D-Glucose <=> alpha,alpha-Trehalose + ADP
GDP-mannose + D-Fructose 6-phosphate <=> GDP + beta-D-Fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate
2 Dimethylallyl diphosphate <=> Diphosphate + Chrysanthemyl diphosphate
2 Dimethylallyl diphosphate <=> Diphosphate + Lavandulyl diphosphate
Dimethylallyl diphosphate + Naringenin <=> Diphosphate + Sophoraflavanone B
Dimethylallyl diphosphate + Leachianone G <=> Diphosphate + Sophoraflavanone G
Aldosterone <=> Aldosterone hemiacetal
11-Deoxycorticosterone + NADPH + H+ <=> 5alpha-Dihydrodeoxycorticosterone + NADP+
5alpha-Dihydrodeoxycorticosterone + NADPH + H+ <=> Allotetrahydrodeoxycorticosterone + NADP+
2-Amino-2-deoxyisochorismate + L-Glutamate <=> Chorismate + L-Glutamine
5alpha-Pregnane-3,20-dione + NADPH + H+ <=> Allopregnanolone + NADP+
5alpha-Pregnan-20alpha-ol-3-one + NADP+ <=> 5alpha-Pregnane-3,20-dione + NADPH + H+
5alpha-Pregnane-3alpha,20alpha-diol + NADP+ <=> Allopregnanolone + NADPH + H+
5alpha-Pregnan-20alpha-ol-3-one + NADPH + H+ <=> 5alpha-Pregnane-3alpha,20alpha-diol + NADP+
ATP + N-Acetyl-D-hexosamine <=> ADP + N-Acetyl-alpha-D-hexosamine 1-phosphate
Dihydrotestosterone + NADPH + H+ <=> Androstan-3alpha,17beta-diol + NADP+
ATP + 5-PP-InsP5 <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
2 5,6-Dihydroxyindole-2-carboxylate + Oxygen <=> 2 5,6-Indolequinone-2-carboxylic acid + 2 H2O
CTP + 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate <=> Diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
N-Acetyl-D-galactosamine + ATP <=> N-Acetyl-alpha-D-galactosamine 1-phosphate + ADP
N-Acetyl-D-glucosamine + ATP <=> N-Acetyl-alpha-D-glucosamine 1-phosphate + ADP
N-Acylsphingosine + Phosphatidylcholine <=> Sphingomyelin + 1,2-Diacyl-sn-glycerol
N-Acyl-L-homoserine lactone + H2O <=> N-Acyl-L-homoserine
DIBOA-glucoside + 2-Oxoglutarate + Oxygen <=> TRIBOA-glucoside + Succinate + CO2
S-Adenosyl-L-methionine + TRIBOA-glucoside <=> S-Adenosyl-L-homocysteine + DIMBOA-glucoside
Pheophorbide a + H2O <=> Pyropheophorbide a + Methanol + CO2
Pheophorbide a + H2O <=> C-13(2)-Carboxypyropheophorbide a + Methanol
C-13(2)-Carboxypyropheophorbide a <=> Pyropheophorbide a + CO2
Cholesterol + 3'-Phosphoadenylyl sulfate <=> Cholesterol sulfate + Adenosine 3',5'-bisphosphate
Pregnenolone + 3'-Phosphoadenylyl sulfate <=> 3beta-Hydroxypregn-5-en-20-one sulfate + Adenosine 3',5'-bisphosphate
7-Isopropyl-4-methyloxepan-2-one + H2O <=> 6-Hydroxy-3,7-dimethyloctanoate
11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 5-phosphate + Orthophosphate
beta-D-Fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate + H2O <=> beta-D-Fructofuranosyl-alpha-D-mannopyranoside + Orthophosphate
N1,N5,N10-Tricoumaroyl spermidine <=> N1,N5,N10-Tricaffeoyl spermidine
N1,N5,N10-Tricaffeoyl spermidine <=> N1,N5,N10-Triferuloyl spermidine
N1,N5,N10-Triferuloyl spermidine <=> N1,N5,N10-Tri(hydroxyferuloyl) spermidine
N1,N5,N10-Tri(hydroxyferuloyl) spermidine + S-Adenosyl-L-methionine <=> N1,N5-Di(hydroxyferuloyl)-N10-sinapoyl spermidine + S-Adenosyl-L-homocysteine
beta-Carotene <=> Strigolactone ABC-rings
Strigolactone ABC-rings <=> 5-Deoxystrigol
5-Deoxystrigol <=> Strigol
3',5'-Cyclic diGMP + H2O <=> 5'-Phosphoguanylyl(3'->5')guanosine
Geranylgeranyl diphosphate + 2 H2O <=> Sclareol + Diphosphate
Geranylgeranyl diphosphate + H2O <=> Geranylgeraniol + Diphosphate
11-Dehydrocorticosterone <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione
Cortisol <=> 11beta-Hydroxyandrost-4-ene-3,17-dione
Umbelliferone + Dimethylallyl diphosphate <=> Demethylsuberosin + Diphosphate
Psoralen + NADPH + Oxygen + H+ <=> Bergaptol + NADP+ + H2O
Psoralen + NADPH + Oxygen + H+ <=> Xanthotoxol + NADP+ + H2O
Umbelliferone + Dimethylallyl diphosphate <=> Osthenol + Diphosphate
UDP-L-arabinose <=> UDP-L-arabinofuranose
Umbelliferone <=> Esculetin
D-Allose 6-phosphate <=> D-Allulose 6-phosphate
D-Allulose 6-phosphate <=> beta-D-Fructose 6-phosphate
Chlorophyllide + 2 H+ <=> Pheophorbide a + Magnesium cation
Acyl-CoA + 1-Acylglycerophosphoinositol <=> CoA + 1-Phosphatidyl-D-myo-inositol
Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine
Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol
Acyl-CoA + Monolysocardiolipin <=> CoA + Cardiolipin
Cardiolipin + H2O <=> Monolysocardiolipin + Fatty acid
4-(beta-D-Glucosyloxy)benzoate + H2O <=> 4-Hydroxybenzoate + D-Glucose
4-Hydroxybenzoate + Geranyl diphosphate <=> Geranyl-hydroxybenzoate + Diphosphate
Geranyl-hydroxybenzoate <=> Geranylhydroquinone
3''-Hydroxy-geranylhydroquinone <=> Deoxyshikonin
Deoxyshikonin <=> Shikonin
Geranylhydroquinone <=> Dihydroshikonofuran
Dihydroshikonofuran <=> Dihydroechinofuran
ATP + Gentamicin A <=> Diphosphate + 2''-Adenylylgentamicin A
3 Cadaverine + 4 Pyruvate <=> 17-Oxosparteine + 4 L-Alanine + 3 H2O
17-Oxosparteine <=> Lupanine
Lupanine <=> 13-Hydroxylupanine
3,6-Dihydronicotinic acid <=> 3,6-Dihydropyridine
Piperideine <=> Piperidine
3-Vinylbacteriochlorophyllide a + H2O <=> 3-Hydroxyethylbacteriochlorophyllide a
3-Hydroxyethylbacteriochlorophyllide a + NAD+ <=> Bacteriochlorophyllide a + NADH + H+
Bacteriochlorophyllide a <=> Bacteriochlorophyllide b
Chlorophyllide + H2O <=> 3-Hydroxyethylchlorophyllide a
Chlorophyllide + H2O <=> 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + Methanol + CO2
Bacteriochlorophyllide d + S-Adenosyl-L-methionine <=> Bacteriochlorophyllide c + S-Adenosyl-L-homocysteine
Bacteriochlorophyllide c + trans,trans-Farnesyl diphosphate <=> Bacteriochlorophyll c + Diphosphate
Bacteriochlorophyllide d + trans,trans-Farnesyl diphosphate <=> Bacteriochlorophyll d + Diphosphate
7(1)-Hydroxychlorophyllide a <=> Chlorophyllide
Chlorophyllide b + Phytyl diphosphate <=> Chlorophyll b + Diphosphate
Chlorophyll b + H2O <=> Chlorophyllide b + Phytol
7(1)-Hydroxychlorophyll a + NAD+ <=> Chlorophyll b + NADH + H+
7(1)-Hydroxychlorophyll a + NADP+ <=> Chlorophyll b + NADPH + H+
1,2-Diacyl-sn-glycerol + S-Adenosyl-L-methionine <=> Diacylglycerylhomoserine + 5'-Methylthioadenosine
Diacylglycerylhomoserine + 3 S-Adenosyl-L-methionine <=> Diacylglyceryl-N,N,N-trimethylhomoserine + 3 S-Adenosyl-L-homocysteine
N1-Acetylspermidine + Oxygen + H2O <=> Putrescine + 3-Acetamidopropanal + Hydrogen peroxide
N8-Acetylspermidine + Oxygen + H2O <=> 1,3-Diaminopropane + N4-Acetylaminobutanal + Hydrogen peroxide
Spermine + Oxygen + H2O <=> Spermidine + 3-Aminopropanal + Hydrogen peroxide
Spermidine + Oxygen + H2O <=> Putrescine + 3-Aminopropanal + Hydrogen peroxide
Diacetyl + NADH + H+ <=> (S)-Acetoin + NAD+
Putrescine + L-Aspartate 4-semialdehyde + NADPH + H+ <=> Carboxyspermidine + H2O + NADP+
1,3-Diaminopropane + L-Aspartate 4-semialdehyde + NADPH + H+ <=> Carboxynorspermidine + H2O + NADP+
Carboxyspermidine <=> Spermidine + CO2
Carboxynorspermidine <=> Norspermidine + CO2
Reduced FMN + Oxygen <=> Dimethylbenzimidazole + D-Erythrose 4-phosphate + H2O
beta-D-Fructose 6-phosphate + ADP <=> beta-D-Fructose 1,6-bisphosphate + AMP
alpha-D-Glucose + ADP <=> alpha-D-Glucose 6-phosphate + AMP
beta-D-Glucose + ADP <=> beta-D-Glucose 6-phosphate + AMP
ATP + Phytic acid <=> ADP + 5-PP-InsP5
Benzoate + Pyruvate <=> Pyruvophenone + CO2
Pyruvophenone <=> D-Cathinone
Tetrahydrofolate + Formaldehyde <=> 5,10-Methylenetetrahydrofolate + H2O
Formate <=> CO2
Methanophenazine + Hydrogen <=> Dihydromethanophenazine
Acetyl-CoA + 5,6,7,8-Tetrahydromethanopterin <=> CoA + 5-Methyl-5,6,7,8-tetrahydromethanopterin + CO
Propanal + NAD+ + CoA <=> Propanoyl-CoA + NADH + H+
Methanol + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + H2O
L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O
D-Fructose 1,6-bisphosphate <=> 3-Phospho-D-glycerate
Bis(4-hydroxyphenyl)methane <=> Bis(4-hydroxyphenyl)methanol
Bis(4-hydroxyphenyl)methanol <=> 4,4'-Dihydroxybenzophenone
4,4'-Dihydroxybenzophenone <=> 4-Hydroxyphenyl-4-hydroxybenzoate
4-Hydroxyphenyl-4-hydroxybenzoate + H2O <=> 4-Hydroxybenzoate + Hydroquinone
Feruloyl-CoA + 16-Hydroxypalmitate <=> CoA + 16-Feruloyloxypalmitate
N-Acetyl-L-citrulline + H2O <=> Acetate + L-Citrulline
Palustradiene <=> Palustradienol
Palustradienol <=> Palustradienal
Palustradienal <=> Palustric acid
Copalyl diphosphate <=> Isopimara-7,15-diene + Diphosphate
Isopimara-7,15-diene <=> Isopimaradienol
Isopimaradienol <=> Isopimaradienal
Isopimaradienal <=> Isopimaric acid
9alpha-Copalyl diphosphate <=> Stemar-13-ene + Diphosphate
9alpha-Copalyl diphosphate <=> Stemod-13(17)-ene + Diphosphate
9alpha-Copalyl diphosphate <=> 9beta-Pimara-7,15-diene + Diphosphate
9beta-Pimara-7,15-dien-19-oate <=> 3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide
ent-Copalyl diphosphate <=> ent-Cassa-12,15-diene + Diphosphate
ent-Copalyl diphosphate <=> (+)-Sandaracopimaradiene + Diphosphate
ent-Copalyl diphosphate <=> ent-Pimara-8(14),15-diene + Diphosphate
Geranylgeranyl diphosphate <=> Fusicocca-2,10(14)-diene + Diphosphate
Trimethylamine + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Dimethylamine
2,5-Dihydroxypyridine + Oxygen <=> N-Formylmaleamic acid
N-Formylmaleamic acid + H2O <=> Maleamate + Formate
S-(Hydroxymethyl)mycothiol + NAD+ <=> S-Formylmycothiol + NADH + H+
1,2,3,4-Tetrachlorobenzene + Oxygen + NADH + H+ <=> cis-Chlorobenzene dihydrodiol + NAD+
1,2,3,4-Tetrachlorobenzene + Oxygen + NADPH + H+ <=> cis-Chlorobenzene dihydrodiol + NADP+
cis-Chlorobenzene dihydrodiol + NAD+ <=> Tetrachlorocatechol + NADH + H+
cis-Chlorobenzene dihydrodiol + NADP+ <=> Tetrachlorocatechol + NADPH + H+
Tetrachlorocatechol + Oxygen <=> Tetrachloro-cis,cis-muconate
Tetrachloro-cis,cis-muconate <=> 2,3,5-Trichlorodienelactone + Hydrochloric acid
2,3,5-Trichlorodienelactone + H2O <=> 2,3,5-Trichloromaleylacetate
2,3,5-Trichloromaleylacetate + 2 NADH + 2 H+ <=> 2,4-Dichloro-3-oxoadipate + 2 NAD+ + Hydrochloric acid
2,3,5-Trichloromaleylacetate + 2 NADPH + 2 H+ <=> 2,4-Dichloro-3-oxoadipate + 2 NADP+ + Hydrochloric acid
2,4-Dichloro-3-oxoadipate <=> CO2
trans,trans-Farnesyl diphosphate + H2O <=> 8-epi-Cedrol + Diphosphate
Trichloroethene + NADH + H+ + Oxygen <=> TCE epoxide + NAD+ + H2O
TCE epoxide <=> CO
TCE epoxide <=> Dichloroacetate
TCE epoxide <=> Glyoxylate
TCE epoxide <=> Formate
Trichloroethene <=> Chloral
Trichloroethene <=> TCE epoxide
1,1,1-Trichloroethane + NADH + H+ + Oxygen <=> Trichloroethanol + NAD+ + H2O
Trichloroethanol <=> Chloral
Chloral <=> Trichloroacetate
Trichloroethene + Oxygen + H2O + NADH + H+ <=> Glyoxylate + 3 Hydrochloric acid + NAD+
Trichloroethene + Oxygen + 2 H2O + NADH + H+ <=> 2 Formate + 3 Hydrochloric acid + NAD+
Sulfoacetaldehyde <=> Coenzyme M
1,1,1-Trichloroethane <=> 1,1-Dichloroethane + Hydrochloric acid
1,1-Dichloroethane <=> Chloroethane + Hydrochloric acid
Trichloroacetate + 2 H2O <=> Oxalate + 3 Hydrochloric acid
Trichloroacetate <=> CO2
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-9,10-dihydrodiol + NAD+
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-7,8-dihydrodiol + NAD+
Pyrene + Oxygen <=> cis-4,5-Dihydroxy-4,5-dihydropyrene
cis-4,5-Dihydroxy-4,5-dihydropyrene + NAD+ <=> 4,5-Dihydroxypyrene + NADH + H+
4,5-Dihydroxypyrene + Oxygen <=> Phenanthrene-4,5-dicarboxylate
Phenanthrene-4,5-dicarboxylate <=> Phenanthrene-4-carboxylate + CO2
Phenanthrene-4-carboxylate + Oxygen + NADH + H+ <=> cis-3,4-Phenanthrenedihydrodiol-4-carboxylate + NAD+
cis-3,4-Phenanthrenedihydrodiol-4-carboxylate <=> Phenanthrene-3,4-diol + CO2
Pyrene + Oxygen <=> Pyrene-4,5-oxide + H2O
Pyrene-4,5-oxide + H2O <=> trans-4,5-Dihydroxy-4,5-dihydropyrene
Pyrene + Oxygen <=> Pyrene-1,2-oxide + H2O
Pyrene-1,2-oxide <=> 1-Hydroxypyrene
1-Hydroxypyrene + Oxygen <=> 1-Hydroxypyrene-6,7-oxide + H2O
1-Hydroxypyrene-6,7-oxide <=> 1,6-Dihydroxypyrene
1,6-Dihydroxypyrene <=> Pyrene-1,6-dione
1-Hydroxypyrene + Oxygen <=> 1-Hydroxypyrene-7,8-oxide + H2O
1-Hydroxypyrene-7,8-oxide <=> 1,8-Dihydroxypyrene
1,8-Dihydroxypyrene <=> Pyrene-1,8-dione
1-Hydroxypyrene + S-Adenosyl-L-methionine <=> 1-Methoxypyrene + S-Adenosyl-L-homocysteine
1-Methoxypyrene + Oxygen <=> 1-Methoxypyrene-6,7-oxide + H2O
1-Methoxypyrene-6,7-oxide <=> 1-Hydroxy-6-methoxypyrene
1-Hydroxypyrene <=> 1-Pyrenylsulfate
Benzo[a]pyrene-cis-7,8-dihydrodiol + Oxygen <=> cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate
Benzo[a]pyrene-cis-9,10-dihydrodiol + NAD+ <=> 9,10-Dihydroxybenzo[a]pyrene + NADH + H+
9,10-Dihydroxybenzo[a]pyrene + Oxygen <=> cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate
cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate <=> 10-Oxabenzo[def]chrysen-9-one + Formate
2-Dehydro-3-deoxy-D-xylonate <=> 2,5-Dioxopentanoate + H2O
C-9 Reduced nonaketamide <=> Nonaketamide monocyclic intermediate + 2 H2O
Nonaketamide monocyclic intermediate <=> Nonaketamide tricyclic intermediate
S-Adenosyl-L-methionine + Pretetramid <=> S-Adenosyl-L-homocysteine + 6-Methylpretetramide
4-Amino-anhydrotetracycline + 2 S-Adenosyl-L-methionine <=> Anhydrotetracycline + 2 S-Adenosyl-L-homocysteine
Oxytetracycline + Coenzyme F420 <=> 5a,11a-Dehydrooxytetracycline + Reduced coenzyme F420
ATP + Malonyl-CoA + L-Glutamine + H2O <=> AMP + Diphosphate + Malonamoyl-CoA + L-Glutamate
Nonaketamide tricyclic intermediate <=> Pretetramid
4-Keto-anhydrotetracycline <=> 4-Amino-anhydrotetracycline
5a,11a-Dehydrotetracycline + NADPH + H+ + Oxygen <=> 5a,11a-Dehydrooxytetracycline + NADP+ + H2O
2,4-Dichlorotoluene + NADH + Oxygen + H+ <=> 4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate <=> 7,8-Dihydropyrene-8-carboxylate
cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate <=> 7,8-Dihydropyrene-7-carboxylate
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-4,5-dihydrodiol + NAD+
Benzo[a]pyrene-cis-4,5-dihydrodiol <=> 4,5-Dihydroxybenzo[a]pyrene
4,5-Dihydroxybenzo[a]pyrene + Oxygen <=> 4,5-Chrysenedicarboxylate
4,5-Chrysenedicarboxylate <=> 4-Chrysenecarboxylate + CO2
4,5-Chrysenedicarboxylate <=> 5-Chrysenecarboxylate + CO2
Benzo[a]pyrene + NADH + H+ + Oxygen <=> Benzo[a]pyrene-cis-11,12-dihydrodiol + NAD+
Benzo[a]pyrene + Oxygen <=> Benzo[a]pyrene-11,12-epoxide
Benzo[a]pyrene-11,12-epoxide + H2O <=> Benzo[a]pyrene-trans-11,12-dihydrodiol
Benzo[a]pyrene-trans-11,12-dihydrodiol <=> 11,12-Dihydroxybenzo[a]pyrene
4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 4,6-Dichloro-3-methylcatechol + NADH + H+
4,6-Dichloro-3-methylcatechol + Oxygen <=> 3,5-Dichloro-2-methylmuconate
3,5-Dichloro-2-methylmuconate <=> 3,5-Dichloro-2-methylmuconolactone
Benzo[a]pyrene-cis-11,12-dihydrodiol <=> 11,12-Dihydroxybenzo[a]pyrene
3,5-Dichloro-2-methylmuconolactone <=> 3-Chloro-2-methyldienelactone + Hydrochloric acid
Pyrene-4,5-dione <=> Phenanthrene-4,5-dicarboxylate
Pyrene-4,5-dione + NADH + H+ <=> 4,5-Dihydroxypyrene + NAD+
3-Chloro-2-methyldienelactone + H2O <=> 3-Chloro-2-methylmaleylacetate
3,5-Dichloro-2-methylmuconate <=> 2-Chloro-5-methyl-cis-dienelactone + Hydrochloric acid
2-Chloro-5-methyl-cis-dienelactone + H2O <=> 2-Chloro-5-methylmaleylacetate
2-Chloro-5-methylmaleylacetate + NADH + H+ <=> 5-Methylmaleylacetate + NAD+ + Hydrochloric acid
5-Methylmaleylacetate + NADH + H+ <=> 2-Methyl-3-oxoadipate + NAD+
3-Methylmuconolactone <=> 4-Methyl-3-oxoadipate-enol-lactone
4-Methyl-3-oxoadipate-enol-lactone + H2O <=> 4-Methyl-3-oxoadipate
Phthalate + Oxygen + NADH + H+ <=> Phthalate 3,4-cis-dihydrodiol + NAD+
Phthalate 3,4-cis-dihydrodiol + NAD+ <=> 3,4-Dihydroxyphthalate + NADH + H+
3-Methyl-cis,cis-hexadienedioate <=> 3-Methylmuconolactone
2,4-Dinitrotoluene + NADH + Oxygen + H+ <=> 4-Methyl-5-nitrocatechol + NAD+ + Nitrite
4-Methyl-5-nitrocatechol + NADPH + Oxygen + H+ <=> 2-Hydroxy-5-methylquinone + NADP+ + Nitrite + H2O
2-Hydroxy-5-methylquinone + NADH + H+ <=> 2,4,5-Trihydroxytoluene + NAD+
2,4,5-Trihydroxytoluene + Oxygen <=> cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate
cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate + H2O <=> (S)-Methylmalonate semialdehyde + Pyruvate
4,5-Dihydroxypyrene <=> Pyrene-4,5-dione
trans,trans-Farnesyl diphosphate + 3 Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + 3 Diphosphate
Geranylgeranyl diphosphate + 2 Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + 2 Diphosphate
trans,trans-Farnesyl diphosphate + 4 Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + 4 Diphosphate
trans,trans-Farnesyl diphosphate + 5 Isopentenyl diphosphate <=> all-trans-Octaprenyl diphosphate + 5 Diphosphate
Geranylgeranyl diphosphate + 5 Isopentenyl diphosphate <=> all-trans-Nonaprenyl diphosphate + 5 Diphosphate
2-Oxo-4-hydroxy-5-aminovalerate <=> 2,5-Dioxopentanoate + Ammonia
L-Tyrosine + Pyruvate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Alanine
Feruloyl-CoA + Agmatine <=> CoA + Feruloylagmatine
p-Coumaroyl-CoA + Putrescine <=> CoA + p-Coumaroylputrescine
Feruloyl-CoA + Putrescine <=> CoA + Feruloylputrescine
3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] <=> 7,9,12-Octaketide intermediate 1
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,9,12-Decaketide intermediate 1
3,5,7,9,11,13,15,17,19-Nonaoxo-henicosanoyl-[acp] <=> 7,9,12-Decaketide intermediate 4
7,9,12-Octaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Octaketide intermediate 2 + NADP+
7,9,12-Decaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Decaketide intermediate 2 + NADP+
7,9,12-Decaketide intermediate 4 + NADPH + H+ <=> 7,9,12-Decaketide intermediate 5 + NADP+
7,9,12-Octaketide intermediate 2 <=> 7,9,12-Octaketide intermediate 3 + 2 H2O
7,9,12-Decaketide intermediate 2 <=> 7,9,12-Decaketide intermediate 3 + 2 H2O
7,9,12-Decaketide intermediate 5 <=> 7,9,12-Decaketide intermediate 6 + 2 H2O
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,12-Decaketide intermediate 1 + H2O
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 9,14-Decaketide intermediate 1 + 2 H2O
Syringic acid + Tetrahydrofolate <=> 3-O-Methylgallate + 5-Methyltetrahydrofolate
3-O-Methylgallate + Tetrahydrofolate <=> Gallate + 5-Methyltetrahydrofolate
3-O-Methylgallate + Oxygen <=> 4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate
4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate + H2O <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate + Methanol
4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate <=> 2-Pyrone-4,6-dicarboxylate + Methanol
5,5'-Dehydrodivanillate + Oxygen + NADPH + H+ <=> 2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl + NADP+ + H2O + Formaldehyde
2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl + Oxygen <=> 4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate
4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate + H2O <=> 5-Carboxyvanillic acid + 4-Methylene-2-oxoglutarate
5-Carboxyvanillic acid <=> Vanillate + CO2
4-Hydroxybutanoic acid + ATP + CoA <=> 4-Hydroxybutyryl-CoA + AMP + Diphosphate
Succinyl-CoA + NADPH + H+ <=> Succinate semialdehyde + NADP+ + CoA
4-Hydroxybutanoic acid + NADP+ <=> Succinate semialdehyde + H+ + NADPH
3-Methylfumaryl-CoA + H2O <=> (3S)-Citramalyl-CoA
2-Methylfumaryl-CoA <=> 3-Methylfumaryl-CoA
3-Hydroxyaminophenol <=> 4-Aminocatechol
4-Aminocatechol + H2O <=> Benzene-1,2,4-triol + Ammonia
3-Hydroxypropionyl-CoA + Diphosphate + AMP <=> 3-Hydroxypropanoate + CoA + ATP
Aminohydroquinone + H2O <=> Benzene-1,2,4-triol + Ammonia
3-Nitrophenol + 2 NADH + 2 H+ <=> 3-Hydroxyaminophenol + 2 NAD+ + H2O
3-Hydroxypropanoate + NADP+ <=> 3-Oxopropanoate + NADPH + H+
(2S)-Ethylmalonyl-CoA + NADP+ <=> Crotonoyl-CoA + CO2 + NADPH + H+
(2R)-Ethylmalonyl-CoA <=> (2S)-Methylsuccinyl-CoA
7,9,12-Octaketide intermediate 3 <=> Octaketide bicyclic intermediate + H2O
Octaketide bicyclic intermediate + NADPH + H+ <=> (S)-Chiral alcohol + NADP+
(S)-Chiral alcohol <=> (S)-Hemiketal
(S)-Hemiketal <=> (S)-DNPA + H2O
Octaketide bicyclic intermediate + NADPH + H+ <=> (R)-Chiral alcohol + NADP+
(R)-Chiral alcohol <=> (R)-Hemiketal
(R)-Hemiketal <=> (R)-DNPA + H2O
Dihydrokalafungin + NADH + H+ <=> Dihydrokalafungin dihydroquinone form + NAD+
Dihydrokalafungin dihydroquinone form + Reduced FMN + Oxygen <=> DHKred-OH + FMN + H2O
6-Deoxydihydrokalafungin + Reduced FMN + Oxygen <=> Dihydrokalafungin + FMN + H2O
7,9,12-Decaketide intermediate 3 <=> Deoxynogalonate
7,9,12-Decaketide intermediate 6 <=> 12-Deoxyaklanonic acid
Deoxynogalonate + Oxygen <=> Nogalonate + H2O
Methyl nogalonate <=> Nogalaviketone
Nogalaviketone + NADPH + H+ <=> Nogalavinone + NADP+
Nogalavinone <=> 1-OH-Nogalamycinone
Aklavinone + dTDP-beta-L-rhodosamine <=> Aclacinomycin T + dTDP
Aclacinomycin T + dTDP-2-deoxy-beta-L-fucose <=> Aclacinomycin S + dTDP
Aclacinomycin S <=> Aclacinomycin N
Aclacinomycin N + Oxygen <=> Aclacinomycin A + Hydrogen peroxide
Aclacinomycin A + Oxygen <=> Aclacinomycin Y + Hydrogen peroxide
epsilon-Rhodomycinone <=> epsilon-Rhodomycin T
epsilon-Rhodomycin T + H2O <=> 15-Demethoxy-epsilon-rhodomycin + Methanol
15-Demethoxy-epsilon-rhodomycin + Oxygen + 2 Glutathione <=> beta-Rhodomycin + CO2 + H2O + Glutathione disulfide
7,9,12-Decaketide intermediate 3 <=> UWM6
UWM6 <=> Rabelomycin
UWM6 <=> 2,3-Dehydro-UWM6 + H2O
2,3-Dehydro-UWM6 <=> Dehydrorabelomycin
2,3-Dehydro-UWM6 + L-Isoleucine <=> Jadomycin A + CO2 + H2O
UWM6 + dTDP-D-olivose <=> C1'-C9-Glycosylated UWM6 + dTDP
Rabelomycin <=> 11-Deoxylandomycinone
11-Deoxylandomycinone <=> Landomycin H
8-D-Olivosyl-landomycin <=> Landomycin D
Landomycin D <=> Landomycin E
7,12-Decaketide intermediate 1 <=> Decaketide tricyclic intermediate
Premithramycin A3 + dTDP-D-olivose <=> 3A-Deolivosylpremithramycin B + dTDP
3A-Deolivosylpremithramycin B + dTDP-D-olivose <=> Premithramycin B + dTDP
Mithramycin DK <=> Mithramycin
9,14-Decaketide intermediate 1 <=> Tetracenomycin F2 + Acyl-carrier protein
Landomycin H <=> 8-D-Olivosyl-landomycin
(2R)-2-Hydroxy-2-methylbutanenitrile <=> Methyl ethyl ketone + Hydrogen cyanide
(S)-Hydroxynitrile <=> Cyanide ion + Aldehyde
Landomycin E <=> Landomycin J
Landomycin J <=> Landomycin B
Landomycin B <=> Landomycin A
L-Arginine + 2-Oxoglutarate + Oxygen <=> beta-Hydroxyarginine + Succinate + CO2
beta-Hydroxyarginine <=> L-Capreomycidine + H2O
Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate
Se-Methyl-L-selenocysteine + H2O <=> Pyruvate + Ammonia + Methaneselenol
Selenite + 4 Glutathione + 2 H+ <=> Selenodiglutathione + Glutathione disulfide + 3 H2O
Selenodiglutathione + Glutathione <=> Glutathioselenol + Glutathione disulfide
S-Adenosyl-L-methionine + Methaneselenol <=> S-Adenosyl-L-homocysteine + Dimethyl selenide
S-Adenosyl-L-methionine + Dimethyl selenide <=> S-Adenosyl-L-homocysteine + Trimethylselenonium
S-Adenosyl-L-methionine + Hydrogen selenide <=> S-Adenosyl-L-homocysteine + Methaneselenol
2 NADPH + 2 H+ + Methylselenic acid <=> 2 NADP+ + 2 H2O + Methaneselenol
Se-Methyl-L-selenocysteine + 4-Methylthio-2-oxobutanoic acid <=> Methylselenopyruvate + L-Methionine
2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O <=> 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + Formate
2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NADH + H+ <=> 2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NAD+
2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NADPH + H+ <=> 2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NADP+
2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O <=> 5-Amino-6-(5'-phospho-D-ribitylamino)uracil + Ammonia
ATP + (R)-Pantoate <=> ADP + (R)-4-Phosphopantoate
ATP + (R)-4-Phosphopantoate + beta-Alanine <=> AMP + Diphosphate + D-4'-Phosphopantothenate
Acyl-[acyl-carrier protein] + sn-Glycerol 3-phosphate <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-carrier protein
Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate
tRNA precursor + 2 CTP + ATP <=> tRNA with a 3' CCA end + 3 Diphosphate
tRNA precursor + CTP <=> tRNA with a 3' cytidine + Diphosphate
tRNA with a 3' cytidine + CTP <=> tRNA with a 3' CC end + Diphosphate
(S)-Limonene + NADH + H+ + Oxygen <=> (4S)-Limonene-1,2-epoxide + NAD+ + H2O
tRNA with a 3' CC end + ATP <=> tRNA with a 3' CCA end + Diphosphate
(4S)-Limonene-1,2-epoxide + H2O <=> (1R,2R,4S)-Limonene-1,2-diol
(1R,2R,4S)-Limonene-1,2-diol + NAD+ <=> (1R,4S)-1-Hydroxy-2-oxolimonene + NADH + H+
(S)-Limonene + NADPH + Oxygen + H+ <=> (4S)-Limonene-1,2-epoxide + NADP+ + H2O
(1R,4S)-1-Hydroxy-2-oxolimonene + NADPH + Oxygen + H+ <=> (4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O
(4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone <=> (3S)-3-Isopropenyl-6-oxoheptanoate
(4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone <=> (3R)-3-Isopropenyl-6-oxoheptanoate
(R)-Limonene + NADPH + Oxygen + H+ <=> Limonene-1,2-epoxide + NADP+ + H2O
Precursor Z + 2 Thiocarboxy-[sulfur-carrier protein] <=> Molybdopterin + 2 Sulfur-carrier protein
(2S)-2-Phospholactate + GTP <=> (2S)-Lactyl-2-diphospho-5'-guanosine + Diphosphate
7,8-Didemethyl-8-hydroxy-5-deazariboflavin + (2S)-Lactyl-2-diphospho-5'-guanosine <=> Coenzyme F420-0 + GMP
Coenzyme F420-0 + GTP + L-Glutamate <=> Coenzyme F420-1 + GDP + Orthophosphate
Coenzyme F420-1 + GTP + L-Glutamate <=> Coenzyme F420 + GDP + Orthophosphate
ATP + Coenzyme F420 + L-Glutamate <=> ADP + Coenzyme F420-3 + Orthophosphate
Codeine + 2-Oxoglutarate + Oxygen <=> Morphine + Formaldehyde + Succinate + CO2
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin Q1 + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin M1 + H2O + NADP+
Aflatoxin M1 + Oxygen + NADPH + H+ <=> Aflatoxin-M1-8,9-epoxide + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin B1-endo-8,9-epoxide + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin B1-exo-8,9-epoxide + H2O + NADP+
Aflatoxin B1-exo-8,9-epoxide + Glutathione <=> Aflatoxin B1exo-8,9-epoxide-GSH
Aflatoxin B1-exo-8,9-epoxide + H2O <=> Aflatoxin B1 diol
Aflatoxin B1 diol <=> Aflatoxin B1 dialdehyde
Aflatoxin B1 dialdehyde <=> 1,2,3,4-Tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal
Aflatoxin B1 dialdehyde <=> alpha-(1,2-Dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde
1,2,3,4-Tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal <=> 6-[2,3-Dihydroxy-1-(hydroxymethyl)propyl]-1,2-dihydro-7-hydroxy-9-methoxy-cyclopenta[c][1]benzopyran-3,4-dione
alpha-(1,2-Dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde <=> 6-[2,3-Dihydroxy-1-(hydroxymethyl)propyl]-1,2-dihydro-7-hydroxy-9-methoxy-cyclopenta[c][1]benzopyran-3,4-dione
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene + H2O + NADP+
1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene + H2O <=> trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene
trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> (1aalpha,2beta,3alpha,11calpha)-1a,2,3,11c-Tetrahydro-6,11-dimethylbenzo[6,7]phenanthro[3,4-b]oxirene-2,3-diol + H2O + NADP+
Malonyl-CoA + Acyl-CoA <=> 3-Oxoacyl-CoA + CoA + CO2
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + NADPH + H+ <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + NADP+
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP+
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + Oxygen + NADPH + H+ <=> 1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + Oxygen + NADPH + H+ <=> alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide + UDP
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> NNAL-N-glucuronide + UDP
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone <=> 4-(Methylnitrosamino)-1-(1-oxido-3-pyridinyl)-1-butanone
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol <=> 4-(Methylnitrosamino)-1-(3-pyridyl-N-oxide)-1-butanol
4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone <=> 4-(Nitrosoamino)-1-(3-pyridinyl)-1-butanone + Formaldehyde
alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol <=> alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol + Formaldehyde
4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone <=> 4-Oxo-1-(3-pyridyl)-1-butanone + N-Nitrosomethanamine
1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol <=> 5-(3-Pyridyl)-2-hydroxytetrahydrofuran + N-Nitrosomethanamine
4-(Nitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O <=> 4-Hydroxy-1-(3-pyridinyl)-1-butanone + Nitrogen + H2O
alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol + H2O <=> 1-(3-Pyridinyl)-1,4-butanediol + Nitrogen + H2O
4-Hydroxy-1-(3-pyridinyl)-1-butanone <=> 3-Succinoylpyridine
5-(3-Pyridyl)-2-hydroxytetrahydrofuran <=> gamma-Hydroxy-3-pyridinebutanoate
1-(3-Pyridinyl)-1,4-butanediol <=> gamma-Hydroxy-3-pyridinebutanoate
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7-Hydroxymethyl-12-methylbenz[a]anthracene + H2O + NADP+
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O + NADP+
7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O <=> trans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene
7-Hydroxymethyl-12-methylbenz[a]anthracene + 3'-Phosphoadenylyl sulfate <=> 7-Hydroxymethyl-12-methylbenz[a]anthracene sulfate + Adenosine 3',5'-bisphosphate
2 Nitric oxide + Menaquinol <=> Nitrous oxide + Menaquinone + H2O
2 Nitric oxide + NADPH + H+ <=> Nitrous oxide + NADP+ + H2O
D-Glucuronate + NAD+ + H2O <=> D-Glucarate + NADH + H+
16-Hydroxypalmitate <=> 16-Oxopalmitate
trans-2,3-Dehydroacyl-CoA + NADPH + H+ <=> Long-chain acyl-CoA + NADP+
Long-chain acyl-CoA + H2O <=> Long-chain fatty acid + CoA
9,10-Epoxystearate + NADPH + Oxygen + H+ <=> 9,10-Epoxy-18-hydroxystearate + NADP+ + H2O
Docosanoic acid + NADPH + Oxygen + H+ <=> 22-Hydroxydocosanoate + NADP+ + H2O
18-Hydroxyoleate <=> 18-Oxooleate
22-Hydroxydocosanoate <=> 22-Oxodocosanoate
16-Oxopalmitate <=> Hexadecanedioate
18-Oxooleate <=> Octadec-9-ene-1,18-dioic-acid
22-Oxodocosanoate <=> Docosanedioate
16-Hydroxypalmitate + NADPH + Oxygen + H+ <=> 10,16-Dihydroxyhexadecanoic acid + NADP+ + H2O
9,10-Dihydroxystearate + NADPH + Oxygen + H+ <=> 9,10,18-Trihydroxystearate + NADP+ + H2O
(9Z)-Octadecenoic acid + Lipid hydroperoxide <=> 9,10-Epoxystearate + Alcohol
18-Hydroxyoleate + Lipid hydroperoxide <=> 9,10-Epoxy-18-hydroxystearate + Alcohol
9,10-Epoxy-18-hydroxystearate + H2O <=> 9,10,18-Trihydroxystearate
9,10-Epoxystearate + H2O <=> 9,10-Dihydroxystearate
Long-chain aldehyde <=> Alkane + CO
Secondary alcohol <=> Ketone
6-Hydroxypseudooxynicotine + 2 H2O <=> 6-Hydroxy-3-succinoylpyridine + Methylamine
6-Hydroxy-3-succinoylpyridine + 2 NADH + 2 H+ + Oxygen <=> 2,5-Dihydroxypyridine + Succinate semialdehyde + 2 NAD+ + H2O
ATP + Acetate + Acyl-carrier protein <=> AMP + Diphosphate + Acetyl-[acyl-carrier protein]
(S)-2,3-Epoxysqualene <=> Taraxerol
Xylitol + NAD+ <=> D-Xylose + NADH + H+
2-Hydroxyethylphosphonate + NAD+ <=> Phosphonoacetaldehyde + NADH + H+
Ethanol + Ubiquinone <=> Acetaldehyde + Ubiquinol
Malonyl-[acyl-carrier protein] <=> Acetyl-[acyl-carrier protein] + CO2
Malonate <=> Acetate + CO2
Long-chain aldehyde + Acyl-carrier protein + NAD+ <=> Long-chain acyl-[acyl-carrier protein] + NADH + H+
Long-chain aldehyde + Acyl-carrier protein + NADP+ <=> Long-chain acyl-[acyl-carrier protein] + NADPH + H+
(1E,4S,5E,7R)-Germacra-1(10),5-dien-11-ol + H2O <=> Geosmin + Acetone
Indole-3-carboxylate <=> Indole + CO2
2 Menaquinol + Oxygen + n H+ <=> 2 Menaquinone + 2 H2O + n H+
N6-(L-1,3-Dicarboxypropyl)-L-lysine + H2O + Oxygen <=> L-2-Aminoadipate 6-semialdehyde + L-Glutamate + Hydrogen peroxide
Dimethyl sulfoxide + H2O + NAD+ <=> Dimethyl sulfone + NADH + H+
Dimethyl sulfide + Menaquinone + H2O <=> Dimethyl sulfoxide + Menaquinol
2 Ubiquinol + Oxygen <=> 2 Ubiquinone + 2 H2O
Thioredoxin + Prostaglandin H2 <=> Thioredoxin disulfide + Prostaglandin F2alpha
Carboxybiotinyl-[protein] + H+ <=> Biotinyl-[protein] + CO2
Protein N6,N6-dimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein N6-methyl-L-lysine + Succinate + Formaldehyde + CO2
Protein N6-methyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein lysine + Succinate + Formaldehyde + CO2
Carbazole + NADPH + H+ + Oxygen <=> 2'-Aminobiphenyl-2,3-diol + NADP+
Methanesulfonic acid + NADH + H+ + Oxygen <=> Formaldehyde + NAD+ + Sulfite + H2O
Urate + NADH + H+ + Oxygen <=> 5-Hydroxyisourate + NAD+ + H2O
Anthranilate + FADH2 + Oxygen <=> 3-Hydroxyanthranilate + FAD + H2O
FAD + NADPH + H+ <=> FADH2 + NADP+
L-Tyrosine + NADP+ + Iodide <=> 3-Iodo-L-tyrosine + NADPH
3-Iodo-L-tyrosine + NADP+ + Iodide <=> 3,5-Diiodo-L-tyrosine + NADPH
S-Adenosyl-L-methionine + Iodide + H+ <=> S-Adenosyl-L-homocysteine + Methyl iodide
Acetoin + CoA + NAD+ <=> Acetaldehyde + Acetyl-CoA + NADH + H+
trans,trans-Farnesyl diphosphate <=> Zingiberene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> beta-Eudesmol + Diphosphate
Benzoyl-CoA + Benzyl alcohol <=> Benzyl benzoate + CoA
UDP-glucuronate + Baicalein <=> UDP + Baicalin
O-Phospho-L-serine + Sulfite <=> L-Cysteate + Orthophosphate
S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + Thermospermine + H+
2,3-Bisphospho-D-glycerate + H2O <=> 2-Phospho-D-glycerate + Orthophosphate
Baicalin + H2O <=> Baicalein + D-Glucuronate
Hesperidin + H2O <=> Hesperetin + Rutinose
Angiotensin II + H2O <=> Angiotensin (1-7) + L-Phenylalanine
Anandamide + H2O <=> Arachidonate + Ethanolamine
Oleamide + H2O <=> (9Z)-Octadecenoic acid + Ammonia
CDP-choline + H2O <=> CMP + Choline phosphate
Salicylate <=> Phenol + CO2
2 Ascorbate + Hydrogen peroxide <=> 2 Monodehydroascorbate + 2 H2O
2 Fe2+ + NADP+ + H+ <=> 2 Fe3+ + NADPH
S-Adenosyl-L-methionine + Malonyl-[acyl-carrier protein] <=> S-Adenosyl-L-homocysteine + Malonyl-[acp] methyl ester
D-Arabinitol 1-phosphate + NAD+ <=> D-Xylulose 5-phosphate + NADH + H+
(R)-2,3-Dihydroxypropane-1-sulfonate + 2 NAD+ + H2O <=> (2R)-3-Sulfolactate + 2 NADH + 2 H+
D-Glucose 6-phosphate + Coenzyme F420 <=> D-Glucono-1,5-lactone 6-phosphate + Reduced coenzyme F420
Ethanol + N,N-Dimethyl-4-nitrosoaniline <=> Acetaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline
Methanol + N,N-Dimethyl-4-nitrosoaniline <=> Formaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline
2,3-Epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O <=> 3,4-Didehydroadipyl-CoA semialdehyde + Formate
Sulfoacetaldehyde + CoA + NADP+ <=> Sulfoacetyl-CoA + NADPH + H+
trans,trans-Farnesyl diphosphate <=> (+)-Germacrene D + Diphosphate
2-Amino-2-deoxyisochorismate + FMN <=> 3-(1-Carboxyvinyloxy)anthranilate + Reduced FMN
7-Chloro-L-tryptophan + Oxygen <=> 2-Imino-3-(7-chloroindol-3-yl)propanoate + Hydrogen peroxide
2 Glutathione amide + NAD+ <=> Glutathione amide disulfide + NADH + H+
Farnesylcysteine + Oxygen + H2O <=> 2-trans,6-trans-Farnesal + L-Cysteine + Hydrogen peroxide
2 Glutathione amide + Hydrogen peroxide <=> Glutathione amide disulfide + 2 H2O
Gallate + Oxygen <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
4 2-Imino-3-(7-chloroindol-3-yl)propanoate + Oxygen <=> 2 3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 2 Ammonia + 2 H2O
4'-O-Demethylrebeccamycin + H2O <=> Dichloroarcyriaflavin A + beta-D-Glucose
4'-O-Demethylrebeccamycin + S-Adenosyl-L-methionine <=> Rebeccamycin + S-Adenosyl-L-homocysteine
L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 7-Chloro-L-tryptophan + FAD + 2 H2O
L-Proline + 2-Oxoglutarate + Oxygen <=> cis-3-Hydroxy-L-proline + Succinate + CO2
trans,trans-Farnesyl diphosphate <=> 5-Epiaristolochene + Diphosphate
N,N-Dihydroxy-L-phenylalanine <=> (E)-Phenylacetaldoxime + CO2 + H2O
N,N-Dihydroxy-L-tryptophan <=> Indole-3-acetaldehyde oxime + CO2 + H2O
Pyrrole-2-carboxylate + NADH + H+ + Oxygen <=> 5-Hydroxypyrrole-2-carboxylate + NAD+ + H2O
D-Alanine + (R)-Lactate + ATP <=> D-Alanyl-(R)-lactate + ADP + Orthophosphate
ATP + 3-Hydroxybenzoate + CoA <=> AMP + Diphosphate + 3-Hydroxybenzoyl-CoA
ATP + D-Aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n <=> [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + Orthophosphate
1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-Cysteine + ATP <=> 1-O-[2-(L-Cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + AMP + Diphosphate
ATP + [L-Asp(4-L-Arg)]n + L-Aspartate <=> ADP + Orthophosphate + [L-Asp(4-L-Arg)]n-L-Asp
ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-Arginine <=> ADP + Orthophosphate + [L-Asp(4-L-Arg)]n+1
ATP + 5,6,7,8-Tetrahydromethanopterin + L-Glutamate <=> ADP + Orthophosphate + Tetrahydrosarcinapterin
D-Alanine + D-Serine + ATP <=> D-Alanyl-D-serine + ADP + Orthophosphate
ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-Lysine <=> ADP + Orthophosphate + N6-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl)-D-lysine
[tRNA(Ile2)]-cytidine34 + L-Lysine + ATP <=> [tRNA(Ile2)]-lysidine34 + AMP + Diphosphate + H2O
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate <=> UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate
all-trans-8'-Apo-beta-carotenal + Oxygen <=> Retinal + (2E,4E,6E)-2,6-Dimethylocta-2,4,6-trienedial
Zeaxanthin + 2 Oxygen <=> Crocetin dialdehyde + 2 (3S)-3-Hydroxycyclocitral
trans,trans-Farnesyl diphosphate <=> (-)-alpha-Gurjunene + Diphosphate
2-cis,6-cis-Farnesyl diphosphate <=> (-)-endo-alpha-Bergamotene + Diphosphate
2-cis,6-cis-Farnesyl diphosphate <=> (+)-alpha-Santalene + Diphosphate
2-cis,6-cis-Farnesyl diphosphate <=> (+)-endo-beta-Bergamotene + Diphosphate
2-cis,6-trans-Farnesyl diphosphate <=> (-)-gamma-Cadinene + Diphosphate
2 S-Adenosyl-L-methionine + Tricetin <=> 2 S-Adenosyl-L-homocysteine + Tricin
S-Adenosyl-L-methionine + Tricetin <=> S-Adenosyl-L-homocysteine + 3'-O-Methyltricetin
S-Adenosyl-L-methionine + 3'-O-Methyltricetin <=> S-Adenosyl-L-homocysteine + Tricin
trans,trans-Farnesyl diphosphate <=> (+)-alpha-Barbatene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Cubenene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-delta-Selinene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-Epicubenol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (3R,6E)-Nerolidol + Diphosphate
trans,trans-Farnesyl diphosphate <=> (E)-gamma-Bisabolene + Diphosphate
trans,trans-Farnesyl diphosphate <=> gamma-Bisabolene + Diphosphate
1-O-[2-(L-Cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + Acetyl-CoA <=> Mycothiol + CoA
trans,trans-Farnesyl diphosphate <=> (S)-beta-Bisabolene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Germacrene C + Diphosphate
(S)-beta-Bisabolene <=> (S)-beta-Macrocarpene
trans,trans-Farnesyl diphosphate <=> cis-Muurola-3,5-diene + Diphosphate
trans,trans-Farnesyl diphosphate <=> cis-Muurola-4(14),5-diene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (-)-Drimenol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Patchoulol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Presilphiperfolan-8beta-ol + Diphosphate
Acetyl-CoA + 3-Hexenol <=> (3Z)-Hex-3-en-1-yl acetate + CoA
beta-D-Galactosyl-(1->4)-L-rhamnose + Orthophosphate <=> L-Rhamnose + alpha-D-Galactose 1-phosphate
Dimethylallyl diphosphate + 2 Isopentenyl diphosphate <=> 2 Diphosphate + 2-cis,6-cis-Farnesyl diphosphate
UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-Inositol 3-phosphate <=> 1-O-(2-Acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + UDP
UDP-glucuronate + Cyanidin 3-O-glucoside <=> UDP + Cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside
UDP-glucuronate + Soyasapogenol B <=> UDP + Soyasapogenol B 3-O-D-glucuronide
S-Adenosyl-L-methionine + Fluoride <=> 5'-Deoxy-5'-fluoroadenosine + L-Methionine
Dimethylallyl diphosphate + L-Tryptophan <=> Diphosphate + 7-(3-Methylbut-2-enyl)-L-tryptophan
S-Adenosyl-L-methionine + Cl- <=> 5-Deoxy-5-chloroadenosine + L-Methionine
ATP + 1,6-Anhydro-N-acetyl-beta-muramate + H2O <=> ADP + N-Acetyl-beta-muramate 6-phosphate
UDP-glucose + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + alpha-D-Glucopyranosyl-diphospho-ditrans,octacis-undecaprenol
UDP-D-xylose + 3-O-alpha-D-Mannopyranosyl-alpha-D-mannopyranose <=> UMP + 3-O-(6-O-alpha-D-Xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose
Fluoroacetyl-CoA + H2O <=> Fluoroacetate + CoA
1,2-Diacyl-sn-glycerol 3-diphosphate + H2O <=> Phosphatidate + Orthophosphate
2-O-(6-Phospho-alpha-mannosyl)-D-glycerate + H2O <=> D-Mannose 6-phosphate + D-Glycerate
N-Acyl-L-homoserine lactone + H2O <=> L-Homoserine lactone + Carboxylate
(R)-Piperazine-2-carboxamide + H2O <=> (R)-Piperazine-2-carboxylate + Ammonia
beta-Alaninamide + H2O <=> beta-Alanine + Ammonia
(S)-Piperazine-2-carboxamide + H2O <=> (S)-Piperazine-2-carboxylate + Ammonia
L-Prolinamide + H2O <=> L-Proline + Ammonia
1-O-[2-(Acetylamino)-2-deoxy-alpha-D-glucopyranosyl]-D-myo-Inositol + H2O <=> 1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + Acetate
15-cis-Phytoene + 2 Plastoquinone <=> 9,15,9'-tricis-zeta-Carotene + 2 Plastoquinol
15-cis-Phytoene + Plastoquinone <=> 15,9'-dicis-Phytofluene + Plastoquinol
15,9'-dicis-Phytofluene + Plastoquinone <=> 9,15,9'-tricis-zeta-Carotene + Plastoquinol
9,15,9'-tricis-zeta-Carotene <=> 9,9'-dicis-zeta-Carotene
Streptothricin F + H2O <=> Streptothricin F acid
5'-Methylthioadenosine + H2O <=> 5'-S-Methyl-5'-thioinosine + Ammonia
5-Nitroanthranilate + H2O <=> 5-Nitrosalicylate + Ammonia
Reduced flavin + NAD+ <=> Flavin + NADH + H+
NDP-glucose + 3-Phospho-D-glycerate <=> NDP + 2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate
2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate + H2O <=> 2-O-(alpha-D-Glucopyranosyl)-D-glycerate + Orthophosphate
ADP-glucose + D-Glycerate <=> 2-O-(alpha-D-Glucopyranosyl)-D-glycerate + ADP
GDP-mannose + D-Glycerate <=> GDP + 2-O-(alpha-D-Mannosyl)-D-glycerate
GDP-mannose + 2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate <=> GDP + 2-O-[2-O-(alpha-D-Mannopyranosyl)-alpha-D-glucopyranosyl]-3-phospho-D-glycerate
5'-S-Methyl-5'-thioinosine + Orthophosphate <=> Hypoxanthine + S-Methyl-5-thio-D-ribose 1-phosphate
CTP + 1D-myo-Inositol 3-phosphate <=> Diphosphate + CDP-1L-myo-inositol
CDP-1L-myo-inositol + 1D-myo-Inositol 3-phosphate <=> CMP + Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
[Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine + H2O <=> [Protein]-L-serine + N-Acetyl-D-glucosamine
[Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine + H2O <=> [Protein]-L-threonine + N-Acetyl-D-glucosamine
Fumonisin B1 + 2 H2O <=> Aminopentol + 2 Propane-1,2,3-tricarboxylate
ATP + Dephospho-CoA <=> 2'-(5-Triphosphoribosyl)-3'-dephospho-CoA + Adenine
UDP-N-acetyl-alpha-D-glucosamine + [Protein]-L-serine <=> UDP + [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine
UDP-N-acetyl-alpha-D-glucosamine + [Protein]-L-threonine <=> UDP + [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine
S-Adenosyl-L-methionine + Tricin <=> S-Adenosyl-L-homocysteine + 3',4',5'-O-Trimethyltricetin
3 S-Adenosyl-L-methionine + Tricetin <=> 3 S-Adenosyl-L-homocysteine + 3',4',5'-O-Trimethyltricetin
(S)-Piperidine-2-carboxamide + H2O <=> L-Pipecolate + Ammonia
ent-Copalyl diphosphate <=> ent-Pimara-9(11),15-diene + Diphosphate
9-cis-Epoxycarotenoid + Oxygen <=> Xanthoxin + 12'-apo-Carotenal
threo-3-Hydroxy-D-aspartate <=> Oxaloacetate + Ammonia
Terpentedienyl diphosphate <=> Terpentetriene + Diphosphate
Geranylgeranyl diphosphate <=> Elisabethatriene + Diphosphate
Copalyl diphosphate + H2O <=> Phyllocladan-16alpha-ol + Diphosphate
Neryl diphosphate <=> beta-Phellandrene + Diphosphate
(S)-2,3-Epoxysqualene <=> Cucurbitadienol
(S)-2,3-Epoxysqualene <=> Protostadienol
1,5-Anhydro-D-fructose <=> 1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose <=> 2-Hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one
1,5-Anhydro-D-fructose <=> 2-Hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O
UDP-N-acetyl-alpha-D-glucosamine <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + H2O
(3R)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA + H2O
9(S)-HPODE <=> Colneleate + H2O
Arabidiol <=> (S)-2,3-Epoxysqualene + H2O
Dammarenediol-II <=> (S)-2,3-Epoxysqualene + H2O
(+)-Linalool <=> Myrcene + H2O
D-5-Monosubstituted hydantoin <=> L-5-Monosubstituted hydantoin
1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose <=> 1,5-Anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose
(5S,6S)-6-Amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate <=> (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate
Geraniol <=> (+)-Linalool
(S)-2,3-Epoxysqualene <=> Thalianol
(S)-2,3-Epoxysqualene <=> Germanicol
(S)-2,3-Epoxysqualene <=> Isomultiflorenol
Squalene <=> Dammara-20,24-diene
(S)-2,3-Epoxysqualene <=> Camelliol C
Geranylgeranyl diphosphate <=> Terpentedienyl diphosphate
Geranylgeranyl diphosphate <=> Tuberculosinyl diphosphate
threo-3-Hydroxy-D-aspartate <=> Glycine + Glyoxylate
D-erythro-3-Hydroxyaspartate <=> Glycine + Glyoxylate
4,4'-Diapophytoene + FAD <=> 4,4'-Diapophytofluene + FADH2
(R)-2-Hydroxybutane-1,2,4-tricarboxylate <=> Homoisocitrate
Peptidoglycan(N-acetyl-D-glucosamine) + n H2O <=> Peptidoglycan-D-glucosamine + n Acetate
[L-Asp(4-L-Arg)]n+1(n) + H2O <=> [L-Asp(4-L-Arg)]n(n-1) + L-Asp(4-L-Arg)
Abscisic acid glucose ester + H2O <=> D-Glucose + Abscisate
trans-Permethrin + H2O <=> (3-Phenoxyphenyl)methanol + (1S,3R)-3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
Pimeloyl-[acyl-carrier protein] methyl ester + H2O <=> Pimeloyl-[acyl-carrier protein] + Methanol
ATP + Molybdopterin <=> Diphosphate + Adenylated molybdopterin
ATP + Hygromycin B <=> ADP + 4-O-Phosphohygromycin B
2-cis,6-trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> n Diphosphate + trans,polycis-Polyprenyl diphosphate
GDP-mannose + D-Glc-beta-(1->4)-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> GDP + D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol
Adenylated molybdopterin + Molybdate <=> Molybdoenzyme molybdenum cofactor + AMP + H2O
Demethylmenaquinol + S-Adenosyl-L-methionine <=> Menaquinol + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + 2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol <=> S-Adenosyl-L-homocysteine + 6-Methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol
Butanoyl-CoA + NADP+ <=> Crotonoyl-CoA + NADPH + H+
Ascorbate + Fe3+ <=> Monodehydroascorbate + Fe2+
Fatty acid + Hydrogen peroxide <=> alpha-Hydroxy fatty acid + H2O
Lupan-3beta,20-diol <=> (S)-2,3-Epoxysqualene + H2O
4,4'-Diapophytofluene + FAD <=> 4,4'-Diapo-zeta-carotene + FADH2
4,4'-Diapo-zeta-carotene + FAD <=> 4,4'-Diaponeurosporene + FADH2
4,4'-Diaponeurosporene + FAD <=> 4,4'-Diapolycopene + FADH2
FADH2 + NAD+ <=> FAD + NADH + H+
Reduced coenzyme F420 + NADP+ <=> Coenzyme F420 + NADPH + H+
Reduced riboflavin + NAD+ <=> Riboflavin + NADH + H+
GDP-glucose + Orthophosphate <=> D-Glucose 1-phosphate + GDP
UDP-alpha-D-galactose + Soyasapogenol B 3-O-D-glucuronide <=> UDP + Soyasaponin III
UDP-L-rhamnose + Soyasaponin III <=> UDP + Soyasaponin I
UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
Versicolorone + NADP+ <=> 1'-Hydroxyversicolorone + NADPH + H+
UDP-glucose + Crocetin <=> UDP + beta-D-Glucosyl crocetin
UDP-glucose + beta-D-Glucosyl crocetin <=> UDP + Bis(beta-D-glucosyl) crocetin
UDP-glucose + beta-D-Gentiobiosyl crocetin <=> UDP + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester
Phosphoenolpyruvate + D-Man-beta-(1->4)-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> 4,6-CH3(COO-)C-D-Man-beta-(1->4)-D-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol + Orthophosphate
Castasterone <=> 26-Hydroxycastasterone
Brassinolide <=> 26-Hydroxybrassinolide
Sedoheptulose 7-phosphate <=> D-glycero-D-manno-Heptose 7-phosphate
Sedoheptulose 7-phosphate <=> D-glycero-alpha-D-manno-Heptose 7-phosphate
D-glycero-alpha-D-manno-Heptose 7-phosphate + ATP <=> D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate + ADP
D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate + H2O <=> D-glycero-alpha-D-manno-Heptose 1-phosphate + Orthophosphate
D-glycero-alpha-D-manno-Heptose 1-phosphate + GTP <=> GDP-D-glycero-alpha-D-manno-heptose + Diphosphate
L-2-Aminoadipate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-gamma-L-alpha-aminoadipate + ADP + Orthophosphate
LysW-gamma-L-alpha-aminoadipate + ATP <=> LysW-gamma-L-alpha-aminoadipyl 6-phosphate + ADP
LysW-gamma-L-alpha-aminoadipyl 6-phosphate + NADPH + H+ <=> LysW-gamma-L-alpha-aminoadipate 6-semialdehyde + NADP+ + Orthophosphate
LysW-gamma-L-alpha-aminoadipate 6-semialdehyde + L-Glutamate <=> LysW-gamma-L-lysine + 2-Oxoglutarate
LysW-gamma-L-lysine + H2O <=> L-Lysine + alpha-Aminoadipate carrier protein LysW
D-arabino-Hex-3-ulose 6-phosphate <=> beta-D-Fructose 6-phosphate
Torulene + Oxygen <=> 4'-Apo-beta,psi-caroten-4'-al + 3-Methyl-2-butenal
4'-Apo-beta,psi-caroten-4'-al + NAD+ + H2O <=> Neurosporaxanthin + NADH + H+
2-Oxoglutarate + Oxygen <=> Ethylene + 3 CO2 + H2O
2-Oxoglutarate + L-Arginine + Oxygen <=> Succinate + CO2 + Guanidine + (S)-1-Pyrroline-5-carboxylate + H2O
Dimethyl sulfide + Oxygen + NADH + H+ <=> Methanethiol + Formaldehyde + NAD+ + H2O
trans,trans-Farnesyl diphosphate + H2O <=> alpha-Eudesmol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-gamma-Eudesmol + Diphosphate
1,1'-Dihydroxylycopene <=> 1-Hydroxy-1,2-dihydrolycopene + H2O
S-Adenosyl-L-methionine + Naringenin <=> S-Adenosyl-L-homocysteine + Sakuranetin
S-Adenosyl-L-methionine + 4'-Hydroxyflavanone <=> S-Adenosyl-L-homocysteine + 4'-Methoxyflavanone
Presqualene diphosphate <=> 4,4'-Diapophytoene + Diphosphate
Pyrrole-2-carboxylate <=> Pyrrole + CO2
Pyrrole-2-carboxylate + H2O <=> Pyrrole + HCO3-
(R)-Lactate <=> Methylglyoxal + H2O
N-Acetyl-alpha-neuraminate <=> N-Acetyl-beta-neuraminate
Nitrilotriacetic acid + Reduced FMN + Oxygen <=> Iminodiacetate + Glyoxylate + FMN + H2O
Ectoine + H2O <=> N(alpha)-Acetyl-L-2,4-diaminobutyrate
N(alpha)-Acetyl-L-2,4-diaminobutyrate + H2O <=> L-2,4-Diaminobutanoate + Acetate
Kaempferol + UDP-L-rhamnose <=> Afzelin + UDP
Quercetin + UDP-L-rhamnose <=> Quercitrin + UDP
Quercitrin + UDP-glucose <=> Quercetin 3-O-rhamnoside 7-O-glucoside + UDP
L-Aspartate 4-semialdehyde + NAD+ + H2O <=> L-Aspartate + NADH + H+
Raucaffrinoline + NADP+ <=> Perakine + NADPH + H+
Prosolanapyrone II + Oxygen <=> Prosolanapyrone III + Hydrogen peroxide
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> (9R,10E,12Z,15Z)-9-Hydroperoxyoctadeca-10,12,15-trienoate
Linoleate + Oxygen <=> (8E,10R,12Z)-10-Hydroperoxy-8,12-octadecadienoate
1-Hydroxy-2-naphthoate + NADPH + H+ + Oxygen <=> Naphthalene-1,2-diol + NADP+ + H2O + CO2
3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + Reduced FMN + Oxygen <=> 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-methionine <=> dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-homocysteine
Mycinamicin VI + S-Adenosyl-L-methionine <=> Mycinamicin III + S-Adenosyl-L-homocysteine
Mycinamicin III + S-Adenosyl-L-methionine <=> Mycinamicin IV + S-Adenosyl-L-homocysteine
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-Oxoglutarate <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-Glutamate
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-Oxoglutarate <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate
Retinyl ester + H2O <=> 13-cis-Retinol + Fatty acid
Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + Orthophosphate
L-Tyrosine + H2O + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + Ammonia + NADH + H+
beta-D-4-Deoxy-Delta4-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O <=> 5-Dehydro-4-deoxy-D-glucuronate + beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc
8-Oxo-dGTP + H2O <=> 8-Oxo-dGMP + Diphosphate
2-Hydroxy-dATP + H2O <=> 2-Hydroxy-dAMP + Diphosphate
UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + H2O <=> 2,4-Bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + UDP
(+)-beta-Caryophyllene + H2O <=> (+)-Caryolan-1-ol
2-Oxepin-2(3H)-ylideneacetyl-CoA + H2O <=> 3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde
2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA <=> 2-Oxepin-2(3H)-ylideneacetyl-CoA
Phenylacetyl-CoA + Oxygen + NADPH + H+ <=> 2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+
3-Oxo-5,6-dehydrosuberyl-CoA + CoA <=> 5-Carboxy-2-pentenoyl-CoA + Acetyl-CoA
Phenylacetyl-CoA + H2O <=> Phenylacetic acid + CoA
2,4-Bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + Phosphoenolpyruvate + H2O <=> Pseudaminic acid + Orthophosphate
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + Acetyl-CoA <=> UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + CoA
Pseudaminic acid + CTP <=> CMP-pseudaminic acid + Diphosphate
trans,trans-Farnesyl diphosphate + Protein-cysteine <=> S-Farnesyl protein + Diphosphate
S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide
Protein C-terminal S-farnesyl-L-cysteine + Methanol <=> Protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O
Protein C-terminal S-farnesyl-L-cysteine methyl ester <=> Farnesylcysteine
2-trans,6-trans-Farnesal <=> (2E,6E)-Farnesol
(2E,6E)-Farnesol + CTP <=> trans,trans-Farnesyl phosphate + CDP
trans,trans-Farnesyl phosphate + CTP <=> trans,trans-Farnesyl diphosphate + CDP
Proansamitocin <=> 19-Chloroproansamitocin
19-Chloroproansamitocin <=> 20-O-Methyl-19-chloroproansamitocin
20-O-Methyl-19-chloroproansamitocin + Carbamoyl phosphate <=> N-Demethyl-desepoxymaytansinol + Orthophosphate
N-Demethyl-desepoxymaytansinol + 2-Methylpropanoyl-CoA <=> N-Demethyl-desepoxyansamitocin P-3 + CoA
N-Demethyl-desepoxyansamitocin P-3 <=> N-Demethylansamitocin P-3
S-Adenosyl-L-methionine + N-Demethylansamitocin P-3 <=> S-Adenosyl-L-homocysteine + Ansamitocin P-3
UDP-glucose + N-Demethylansamitocin P-3 <=> UDP + Ansamitocinoside P-3
Ansamitocinoside P-3 + Carbamoyl phosphate <=> 4''-O-Carbamoyl ansamitocinoside P-3 + Orthophosphate
Taxa-4(20),11(12)-dien-5alpha-acetoxy-10beta-ol + Oxygen + NADPH + H+ <=> 10beta,14beta-Dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O
S-Adenosyl-L-methionine + Resveratrol <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4',5-dihydroxy-trans-stilbene
S-Adenosyl-L-methionine + 3-Methoxy-4',5-dihydroxy-trans-stilbene <=> S-Adenosyl-L-homocysteine + Pterostilbene
2 S-Adenosyl-L-methionine + Resveratrol <=> 2 S-Adenosyl-L-homocysteine + Pterostilbene
Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose
Geranylgeranyl diphosphate + H2O <=> (13E)-Labda-7,13-dien-15-ol + Diphosphate
Leukotriene C4 + H2O <=> Leukotriene D4 + L-Glutamate
8-Oxoguanine + H2O <=> Urate + Ammonia
8-Oxo-dGDP + H2O <=> 8-Oxo-dGMP + Orthophosphate
P1,P6-Bis(5'-adenosyl)hexaphosphate + H2O <=> 2 ATP
Bis(5'-adenosyl) pentaphosphate + H2O <=> ATP + ADP
P1,P6-Bis(5'-adenosyl)hexaphosphate + H2O <=> Adenosine 5'-pentaphosphate + AMP
Bis(5'-adenosyl) pentaphosphate + H2O <=> Adenosine tetraphosphate + AMP
3-Hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + (2Z,4Z)-2-Hydroxyhexa-2,4-dienoate
9alpha-Hydroxyandrosta-1,4-diene-3,17-dione <=> 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
trans,trans-Farnesyl diphosphate <=> 7-epi-alpha-Selinene + Diphosphate
trans,trans-Farnesyl diphosphate <=> alpha-Guaiene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Viridiflorene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-beta-Caryophyllene + Diphosphate
trans,trans-Farnesyl diphosphate <=> 5-epi-alpha-Selinene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Cubebol + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-gamma-Cadinene + Diphosphate
trans,trans-Farnesyl diphosphate <=> delta-Guaiene + Diphosphate
trans,trans-Farnesyl diphosphate <=> gamma-Curcumene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-alpha-Cuprenene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Avermitilol + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-delta-Cadinene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-T-Muurolol + Diphosphate
9alpha-Copalyl diphosphate <=> (12E)-9alpha-Labda-8(17),12,14-triene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Bicyclogermacrene + Diphosphate
trans,trans-Farnesyl diphosphate <=> 7-epi-Sesquithujene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Sesquithujene + Diphosphate
ent-Copalyl diphosphate <=> ent-Isokaurene + Diphosphate
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose
8(R)-HPODE <=> 5S,8R-DiHODE
(S)-2,3-Epoxysqualene <=> Shionone
(S)-2,3-Epoxysqualene <=> Parkeol
(S)-2,3-Epoxysqualene <=> Achilleol B
(S)-2,3-Epoxysqualene <=> Glutinol
(S)-2,3-Epoxysqualene <=> Friedelin
(S)-2,3-Epoxysqualene <=> Baccharis oxide
(S)-2,3-Epoxysqualene <=> alpha-seco-Amyrin
(S)-2,3-Epoxysqualene <=> Marneral
(S)-2,3-Epoxysqualene <=> beta-seco-Amyrin
(S)-2,3-Epoxysqualene <=> delta-Amyrin
(S)-2,3-Epoxysqualene <=> Tirucalla-7,24-dien-3beta-ol
(S)-2,3-Epoxysqualene <=> Baruol
Prosolanapyrone III <=> (-)-Solanapyrone A
Delta4-Dafachronic acid <=> Androstenedione
Cholesterol + NAD+ <=> Cholest-4-en-3-one + NADH + H+
(6E)-8-Hydroxygeraniol + NADP+ <=> (6E)-8-Hydroxygeranial + NADPH + H+
(6E)-8-Hydroxygeranial + NADP+ <=> (6E)-8-Oxogeranial + NADPH + H+
(6E)-8-Hydroxygeraniol + NADP+ <=> (6E)-8-Oxogeraniol + NADPH + H+
(6E)-8-Oxogeraniol + NADP+ <=> (6E)-8-Oxogeranial + NADPH + H+
Eugenol + Carboxylate + NADP+ <=> Coniferyl ester + NADPH + H+
Isoeugenol + Acetate + NADP+ <=> Coniferyl acetate + NADPH + H+
(S)-Benzoin + NADP+ <=> Benzil + NADPH + H+
(R)-Benzoin + NADP+ <=> Benzil + NADPH + H+
(+)-Sabinene + NADPH + H+ + Oxygen <=> (+)-cis-Sabinol + NADP+ + H2O
Uracil + Reduced FMN + Oxygen <=> (Z)-3-Ureidoacrylate peracid + FMN
Thymine + Reduced FMN + Oxygen <=> (Z)-2-Methylureidoacrylate peracid + FMN
S-Adenosyl-L-methionine + 5-Guanidino-2-oxopentanoate <=> S-Adenosyl-L-homocysteine + 5-Guanidino-3-methyl-2-oxopentanoate
S-Adenosyl-L-methionine + Geranyl diphosphate <=> S-Adenosyl-L-homocysteine + (E)-2-Methylgeranyl diphosphate
Nigerose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate
Chitobiose + Orthophosphate <=> N-Acetyl-D-glucosamine + N-Acetyl-alpha-D-glucosamine 1-phosphate
4-O-beta-D-Mannopyranosyl-D-glucopyranose + Orthophosphate <=> D-Glucose + D-Mannose 1-phosphate
CTP + 1,2-Diacyl-sn-glycerol <=> CDP + Phosphatidate
ATP + Maltose <=> ADP + alpha-Maltose 1-phosphate
ATP + UDP-N-acetyl-alpha-D-glucosamine <=> ADP + UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate
(Z)-3-Ureidoacrylate peracid + H2O <=> (Z)-3-Peroxyaminoacrylate + Carbamate
(Z)-3-Ureidoacrylate peracid + H2O <=> (Z)-3-Peroxyaminoacrylate + CO2 + Ammonia
(Z)-2-Methylureidoacrylate peracid + H2O <=> (Z)-2-Methylperoxyaminoacrylate + Carbamate
(Z)-2-Methylureidoacrylate peracid + H2O <=> (Z)-2-Methylperoxyaminoacrylate + CO2 + Ammonia
1D-chiro-Inositol + NAD+ <=> 1-Keto-D-chiro-inositol + NADH + H+
1-Keto-D-chiro-inositol <=> 2,4,6/3,5-Pentahydroxycyclohexanone
scyllo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+
scyllo-Inositol + NADP+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADPH + H+
5-Androstene-3,17-dione <=> Androstenedione
Epiandrosterone + NAD+ <=> 5alpha-Androstane-3,17-dione + NADH + H+
Dehydroepiandrosterone + NAD+ <=> 5-Androstene-3,17-dione + NADH + H+
(2S)-Ethylmalonyl-CoA <=> Butanoyl-CoA + CO2
7,8-Dihydroneopterin 3'-triphosphate + H2O <=> 6-Carboxy-5,6,7,8-tetrahydropterin + Acetaldehyde + Triphosphate
4-Hydroxy-2-oxohexanoic acid <=> (2Z,4Z)-2-Hydroxyhexa-2,4-dienoate + H2O
Geranyl diphosphate <=> Tricyclene + Diphosphate
Geranyl diphosphate <=> (E)-beta-Ocimene + Diphosphate
Geranyl diphosphate <=> (+)-3-Carene + Diphosphate
Geranyl diphosphate + H2O <=> 1,8-Cineole + Diphosphate
Geranyl diphosphate <=> (-)-Sabinene + Diphosphate
Geranyl diphosphate <=> (+)-Sabinene + Diphosphate
Copal-8-ol diphosphate <=> Geranylgeranyl diphosphate + H2O
Geranyl diphosphate + H2O <=> (R)-(+)-alpha-Terpineol + Diphosphate
Geranyl diphosphate <=> gamma-Terpinene + Diphosphate
Geranyl diphosphate <=> alpha-Terpinene + Diphosphate
Geranyl diphosphate <=> (+)-Camphene + Diphosphate
Geranyl diphosphate <=> (-)-Camphene + Diphosphate
(E)-2-Methylgeranyl diphosphate + H2O <=> 2-Methylisoborneol + Diphosphate
Geranyl diphosphate <=> (+)-alpha-Pinene + Diphosphate
Geranyl diphosphate <=> (+)-beta-Pinene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Sesquiphellandrene + Diphosphate
2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate
7-Carboxy-7-carbaguanine + Ammonia + ATP <=> 7-Cyano-7-carbaguanine + ADP + Orthophosphate + H2O
(2S)-Ethylmalonyl-CoA <=> (2R)-Ethylmalonyl-CoA
Ureidoacrylate + H2O <=> Aminoacrylate + Carbamate
(Z)-3-Ureidoacrylate peracid + NADH + H+ <=> Ureidoacrylate + NAD+ + H2O
(Z)-3-Peroxyaminoacrylate <=> Aminoacrylate
Aminoacrylate + H2O <=> 3-Oxopropanoate + Ammonia
(-)-endo-Fenchol + NAD+ <=> (1S,4R)-(+)-Fenchone + NADH + H+
(-)-endo-Fenchol + NADP+ <=> (1S,4R)-(+)-Fenchone + NADPH + H+
(+)-Thujan-3-ol + NAD+ <=> (+)-Thujan-3-one + NADH + H+
(+)-Thujan-3-ol + NADP+ <=> (+)-Thujan-3-one + NADPH + H+
10-Hydroxy-alpha-humulene + NAD+ <=> Zerumbone + NADH + H+
L-threo-7,8-Dihydrobiopterin + NADP+ <=> Sepiapterin + NADPH + H+
L-threo-Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H+
2,3-Epoxymenaquinone + Gla protein + H2O <=> Menaquinol + Gla protein precursor + CO2 + Oxygen
2,3-Epoxymenaquinone + Dithiothreitol <=> Menaquinone + Oxidized dithiothreitol + H2O
4-Amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-Amino-5-hydroxymethyl-2-methylpyrimidine + Ammonia
alpha-Maltose 1-phosphate + Amylose(n) <=> Orthophosphate + Amylose(n+2)
Starch <=> alpha,alpha-Trehalose
Methanethiol + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Hydrogen sulfide
Methylamine + Coenzyme M <=> Ammonia + 2-(Methylthio)ethanesulfonate
Dimethylamine + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Methylamine
Coenzyme M + Methyl-Co(III) corrinoid protein <=> 2-(Methylthio)ethanesulfonate + Co(I) corrinoid protein
Methanethiol + Co(I) corrinoid protein <=> Hydrogen sulfide + Methyl-Co(III) corrinoid protein
6-Carboxy-5,6,7,8-tetrahydropterin <=> 7-Carboxy-7-carbaguanine + Ammonia
[(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA <=> AMP + Diphosphate + [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA
trans,trans-Farnesyl diphosphate <=> alpha-Muurolene + Diphosphate
trans,trans-Farnesyl diphosphate <=> gamma-Muurolene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Copaene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Cubebene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Sativene + Diphosphate
all-trans-Heptaprenyl diphosphate <=> Tetraprenyl-beta-curcumene + Diphosphate
L-Lysine <=> (2R,3R)-3-Methylornithine
(2R,3R)-3-Methylornithinyl-N6-lysine + NAD+ + H2O <=> (2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine + Ammonia + NADH + H+
(2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine <=> L-Pyrrolysine + H2O
Methylamine + Co(I) corrinoid protein <=> Ammonia + Methyl-Co(III) corrinoid protein
Dimethylamine + Co(I) corrinoid protein <=> Methylamine + Methyl-Co(III) corrinoid protein
Trimethylamine + Co(I) corrinoid protein <=> Dimethylamine + Methyl-Co(III) corrinoid protein
Tetramethylammonium + Co(I) corrinoid protein <=> Trimethylamine + Methyl-Co(III) corrinoid protein
Papaveroxine <=> Narcotine hemiacetal
Narcotine hemiacetal + NAD+ <=> alpha-Narcotine + NADH + H+
(+)-exo-5-Hydroxycamphor + NAD+ <=> (+)-Bornane-2,5-dione + NADH + H+
5-Oxo-1,2-campholide <=> [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetate
N,N-Dihydroxy-L-isoleucine <=> (E)-2-Methylbutanal oxime + CO2 + H2O
(E)-2-Methylbutanal oxime <=> (Z)-2-Methylbutanal oxime
N,N-Dihydroxy-L-valine <=> (E)-2-Methylpropanal oxime + CO2 + H2O
(E)-2-Methylpropanal oxime <=> (Z)-2-Methylpropanal oxime
Dhurrin + H2O <=> (S)-4-Hydroxymandelonitrile + beta-D-Glucose
(Z)-2-Methylbutanal oxime + NADPH + H+ + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + NADP+ + 2 H2O
(2R)-2-Hydroxy-2-methylbutanenitrile + UDP-glucose <=> UDP + Lotaustralin
(Z)-2-Methylpropanal oxime + NADPH + H+ + Oxygen <=> Acetone cyanohydrin + NADP+ + 2 H2O
Lotaustralin + H2O <=> (2R)-2-Hydroxy-2-methylbutanenitrile + beta-D-Glucose
Linamarin + H2O <=> Acetone cyanohydrin + beta-D-Glucose
(E)-Phenylacetaldoxime <=> (Z)-Phenylacetaldehyde oxime
Benzene + Oxygen + NADH + H+ <=> Phenol + NAD+ + H2O
Phenol + Oxygen + NADH + H+ <=> Catechol + NAD+ + H2O
[(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + Oxygen + NADPH + H+ <=> [(2R)-3,3,4-Trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP+ + H2O
(+)-Camphor + NADPH + H+ + Oxygen <=> (+)-6-exo-Hydroxycamphor + NADP+ + H2O
Nicotinate D-ribonucleoside + H2O <=> Nicotinate + D-Ribose
Methylglyoxal + D-Fructose 1,6-bisphosphate <=> D-Glyceraldehyde 3-phosphate + 6-Deoxy-5-ketofructose 1-phosphate
Methylglyoxal + D-Fructose 1-phosphate <=> D-Glyceraldehyde + 6-Deoxy-5-ketofructose 1-phosphate
Bornane-2,6-dione + H2O <=> [(1S)-4-Hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate
(2R,3S)-3-Isopropylmalate + NAD+ <=> 4-Methyl-2-oxopentanoate + CO2 + NADH + H+
L-Gulono-1,4-lactone + Oxygen <=> Ascorbate + Hydrogen peroxide
L-Lysine + NAD+ <=> (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia
Violaxanthin + 2 Ascorbate <=> Zeaxanthin + 2 Dehydroascorbate + 2 H2O
Protein N6,N6-dimethyl-L-lysine + 2 2-Oxoglutarate + 2 Oxygen <=> Protein lysine + 2 Succinate + 2 Formaldehyde + 2 CO2
L-Tyrosine + 2 NADP+ + 2 Iodide <=> 3,5-Diiodo-L-tyrosine + 2 NADPH
2 S-Adenosyl-L-methionine + Glycine <=> 2 S-Adenosyl-L-homocysteine + N,N-Dimethylglycine
2 S-Adenosyl-L-methionine + Sarcosine <=> 2 S-Adenosyl-L-homocysteine + Betaine
3 S-Adenosyl-L-methionine + Glycine <=> 3 S-Adenosyl-L-homocysteine + Betaine
2 UDP-glucose + Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside <=> 2 UDP + Ternatin C5
2 ATP + D-myo-Inositol 1,4,5-trisphosphate <=> 2 ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
(11R)-Dihydroartemisinic aldehyde + NADP+ <=> Artemisinic aldehyde + NADPH + H+
Abieta-7,13-dien-18,18-diol <=> Abietal + H2O
Cyanate + HCO3- + H+ <=> Ammonia + 2 CO2
2-Oxoglutarate + L-Arginine + Oxygen <=> Succinate + CO2 + L-Hydroxyarginine
L-Hydroxyarginine <=> Guanidine + (S)-1-Pyrroline-5-carboxylate + H2O
D-Ribose 5-phosphate + D-Glyceraldehyde 3-phosphate + Ammonia <=> Pyridoxal phosphate + 4 H2O + Orthophosphate
D-Ribose 5-phosphate + D-Glyceraldehyde 3-phosphate + L-Glutamine <=> Pyridoxal phosphate + L-Glutamate + 3 H2O + Orthophosphate
Citrate + N6-Acetyl-N6-hydroxy-L-lysine + ATP <=> N2-Citryl-N6-acetyl-N6-hydroxy-L-lysine + AMP + Diphosphate
N2-Citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-Acetyl-N6-hydroxy-L-lysine + ATP <=> Aerobactin + AMP + Diphosphate
HCO3- + H+ <=> CO2 + H2O
ATP + Isopentenyl phosphate <=> ADP + Isopentenyl diphosphate
2'-Deamino-2'-hydroxyneamine + 2-Oxoglutarate <=> 2'-Deamino-2'-hydroxy-6'-dehydroparomamine + L-Glutamate
Decaprenol phosphate + 5-Phospho-alpha-D-ribose 1-diphosphate <=> trans,octacis-Decaprenylphospho-beta-D-ribofuranose 5-phosphate + Diphosphate
UDP-glucose + 2-Deoxystreptamine <=> UDP + 2'-Deamino-2'-hydroxyparomamine
2,4-Dichloro-2,5-dihydro-5-oxofuran-2-acetate <=> cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid
3-O-alpha-D-Glucopyranosyl-L-rhamnopyranose + Orthophosphate <=> L-Rhamnose + beta-D-Glucose 1-phosphate
UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + Acetyl-CoA <=> UDP-N,N'-diacetylbacillosamine + CoA
Acetyl-CoA + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate <=> CoA + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate
4-Methylaminobutyrate + Oxygen + H2O <=> Succinate semialdehyde + Methylamine + Hydrogen peroxide
4-Methylaminobutyrate + Oxygen + H2O <=> 4-Aminobutanoate + Formaldehyde + Hydrogen peroxide
4-Oxo-1-(3-pyridyl)-1-butanone + NADP+ + H2O <=> 3-Succinoylpyridine + NADPH + H+
L-Arginine + Oxygen + NADH + H+ <=> N(omega)-Hydroxyarginine + NAD+ + H2O
2 N(omega)-Hydroxyarginine + NADH + H+ + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + NAD+ + 2 H2O
5-Nitrosalicylate + Oxygen <=> 2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + Nitrite
5-Nitrosalicylate + Oxygen <=> 4-Nitro-6-oxohepta-2,4-dienedioate
4-Nitro-6-oxohepta-2,4-dienedioate <=> 2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + Nitrite
trans,octacis-Decaprenylphospho-beta-D-ribofuranose + FAD <=> trans,octacis-Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
trans,octacis-Decaprenylphospho-beta-D-arabinofuranose + NAD+ <=> trans,octacis-Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH + H+
Ecgonine methyl ester + NADP+ <=> Ecgonone methyl ester + NADPH + H+
Malonyl-[acp] methyl ester + Malonyl-[acyl-carrier protein] <=> 3-Ketoglutaryl-[acp] methyl ester + CO2 + Acyl-carrier protein
3-Ketoglutaryl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxyglutaryl-[acp] methyl ester + NADP+
3-Hydroxyglutaryl-[acp] methyl ester <=> Enoylglutaryl-[acp] methyl ester + H2O
Enoylglutaryl-[acp] methyl ester + NADPH + H+ <=> Glutaryl-[acp] methyl ester + NADP+
Glutaryl-[acp] methyl ester + Malonyl-[acyl-carrier protein] <=> 3-Ketopimeloyl-[acp] methyl ester + CO2 + Acyl-carrier protein
3-Ketopimeloyl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxypimeloyl-[acp] methyl ester + NADP+
3-Hydroxypimeloyl-[acp] methyl ester <=> Enoylpimeloyl-[acp] methyl ester + H2O
Enoylpimeloyl-[acp] methyl ester + NADPH + H+ <=> Pimeloyl-[acyl-carrier protein] methyl ester + NADP+
Pimeloyl-[acyl-carrier protein] + L-Alanine <=> 8-Amino-7-oxononanoate + Acyl-carrier protein + CO2
beta-Citronellol + NAD+ <=> (R)-(+)-Citronellal + NADH + H+
(-)-Citronellol + NAD+ <=> (S)-(-)-Citronellal + NADH + H+
Biotin sulfoxide + NADPH + H+ <=> Biotin + NADP+ + H2O
Chanoclavine-I + NAD+ <=> Chanoclavine-I aldehyde + NADH + H+
Secoisolariciresinol + 2 NAD+ <=> Matairesinol + 2 NADH + 2 H+
2-Deoxy-scyllo-inosamine + NADP+ <=> 3-Amino-2,3-dideoxy-scyllo-inosose + NADPH + H+
3,3'-Bipyridine-2,2',5,5',6,6'-hexol + NAD+ <=> Blue pigment + NADH + H+
3,3'-Bipyridine-2,2',5,5',6,6'-hexol + NADP+ <=> Blue pigment + NADPH + H+
Azomycin + H2O <=> Imidazol-2-one + Nitrite
Mycophenolic acid O-acyl-glucuronide + H2O <=> Mycophenolate + D-Glucuronate
2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> Maleylpyruvate
Vanillate + Tetrahydrofolate <=> 3,4-Dihydroxybenzoate + 5-Methyltetrahydrofolate
UDP-N-acetyl-alpha-D-glucosamine + Decaprenol phosphate <=> UMP + N-Acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + NAD+ <=> UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H+
UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-Glutamate <=> UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-Oxoglutarate
Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-D-galactose <=> CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose
Pentalenolactone D + 2-Oxoglutarate + Oxygen <=> Pentalenolactone E + Succinate + CO2 + H2O
Pentalenolactone E + 2-Oxoglutarate + Oxygen <=> Pentalenolactone F + Succinate + CO2
Pentalenolactone D + 2 2-Oxoglutarate + 2 Oxygen <=> Pentalenolactone F + 2 Succinate + 2 CO2 + H2O
L-Aspartate 4-semialdehyde + Pyruvate <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
Thiosulfate + Menaquinol <=> HSO3- + Hydrogen sulfide + Menaquinone
L-Glutamate <=> 3-Aminopentanedioate
1-Deoxy-11-oxopentalenate + NADPH + H+ + Oxygen <=> Pentalenolactone D + NADP+ + H2O
1-Deoxy-11-oxopentalenate + NADPH + H+ + Oxygen <=> Neopentalenolactone D + NADP+ + H2O
1-Deoxy-11beta-hydroxypentalenate + NAD+ <=> 1-Deoxy-11-oxopentalenate + NADH + H+
1-Deoxypentalenate + 2-Oxoglutarate + Oxygen <=> 1-Deoxy-11beta-hydroxypentalenate + Succinate + CO2
Cannabigerolate + Oxygen <=> Cannabidiolic acid + Hydrogen peroxide
Propanoyl-CoA + NAD+ <=> Propenoyl-CoA + NADH + H+
Festuclavine + NAD+ <=> 6,8-Dimethyl-6,7-didehydroergoline + NADH + H+
4-(3-Methylbut-2-enyl)-L-tryptophan + S-Adenosyl-L-methionine <=> 4-Dimethylallyl-L-abrine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + Squalene <=> S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene <=> S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
2 S-Adenosyl-L-methionine + Squalene <=> 2 S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
Octanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 3-Oxodecanoyl-[acp] + CoA + CO2
Malonyl-CoA + 2-Hydroxybenzoyl-CoA <=> 2 CoA + 4-Hydroxycoumarin + CO2
Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-D-glucose <=> CoA + dTDP-4-acetamido-4,6-dideoxy-D-glucose
dTDP-L-rhamnose + N-Acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP + alpha-L-Rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
Geranyl diphosphate + 2,4-Dihydroxy-6-pentylbenzoate <=> Diphosphate + Cannabigerolate
2 Geranylgeranyl diphosphate <=> 15-cis-Phytoene + 2 Diphosphate
4-Aminobutanoate + Pyruvate <=> Succinate semialdehyde + L-Alanine
4-Aminobutanoate + Glyoxylate <=> Succinate semialdehyde + Glycine
L-Tryptophan + Pyruvate <=> Indolepyruvate + L-Alanine
Indolepyruvate + NADPH + H+ + Oxygen <=> Indole-3-acetate + NADP+ + H2O + CO2
CTP + N,N'-Diacetyllegionaminate <=> CMP-N,N'-diacetyllegionaminate + Diphosphate
UTP + N-Acetyl-alpha-D-galactosamine 1-phosphate <=> Diphosphate + UDP-N-acetyl-D-galactosamine
UDP-N,N'-diacetylbacillosamine + tritrans,heptacis-Undecaprenyl phosphate <=> UMP + N,N'-Diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol
ATP + Methylphosphonate <=> alpha-D-Ribose 1-methylphosphonate 5-triphosphate + Adenine
alpha-D-Ribose 1-methylphosphonate 5-triphosphate + H2O <=> alpha-D-Ribose 1-methylphosphonate 5-phosphate + Diphosphate
UDP-N,N'-diacetylbacillosamine + H2O <=> UDP + 2,4-Diacetamido-2,4,6-trideoxy-D-mannopyranose
UDP-N-acetyl-D-galactosamine + N,N'-Diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol <=> UDP + N-Acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol
(S)-2-Hydroxyacid + NAD+ <=> 2-Oxo acid + NADH + H+
dTDP-6-deoxy-beta-L-talose + NAD+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADH + H+
2-Hydroxyethylphosphonate + Oxygen <=> Methylphosphonate + HCO3-
Zeaxanthin + Oxygen <=> (3R)-11-cis-3-Hydroxyretinal + (3R)-all-trans-3-Hydroxyretinal
C30 Botryococcene + NADP+ + Diphosphate <=> Presqualene diphosphate + NADPH + H+
S-Adenosyl-L-methionine + C30 Botryococcene <=> S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene <=> S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene
S-Adenosyl-L-methionine + C30 Botryococcene <=> S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene
S-Adenosyl-L-methionine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene <=> S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene
2 S-Adenosyl-L-methionine + C30 Botryococcene <=> 2 S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene
Acetyl-CoA + Fumigaclavine B <=> CoA + Fumigaclavine A
Fumigaclavine A + Dimethylallyl diphosphate <=> Fumigaclavine C + Diphosphate
Dimethyl sulfone + 2 Reduced FMN + 2 Oxygen <=> Methanesulfonic acid + Formaldehyde + 2 FMN + 2 H2O
alpha-D-Ribose 1,2-cyclic phosphate 5-phosphate + H2O <=> D-Ribose 1,5-bisphosphate
Methanesulfonic acid + Reduced FMN + Oxygen <=> FMN + Sulfite + H2O + Formaldehyde
2'-Deamino-2'-hydroxyparomamine + Oxygen <=> 2'-Deamino-2'-hydroxy-6'-dehydroparomamine + Hydrogen peroxide
(3R)-3-Hydroxyacyl-[acyl-carrier protein] <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O
tRNA guanine + 7-Aminomethyl-7-carbaguanine <=> tRNA 7-aminomethyl-7-carbaguanine + Guanine
2-Oxoglutaryl-CoA + H2O <=> 2-Oxoglutarate + CoA
S-(5-Hydroxy-2-furoyl)-CoA + H2O <=> 2-Oxoglutaryl-CoA
Furfural + H2O + Oxygen <=> 2-Furoate + Hydrogen peroxide
2,5-Furandicarboxylate <=> 2-Furoate + CO2
5-Hydroxymethyl-2-furaldehyde + H2O + Oxygen <=> 5-Hydroxymethyl-2-furoate + Hydrogen peroxide
Furfural + NADH + H+ <=> Furfuryl alcohol + NAD+
5-Hydroxymethyl-2-furaldehyde + NADH + H+ <=> 5-Hydroxymethylfurfuryl alcohol + NAD+
Acetyl-CoA + Tetrahydrosarcinapterin <=> CoA + 5-Methyl-H4SPT + CO
S-Adenosyl-L-methionine + tRNA 7-aminomethyl-7-carbaguanine <=> L-Methionine + Adenine + Epoxyqueuosine in tRNA
6-Phospho-D-gluconate + NAD+ <=> D-Ribulose 5-phosphate + CO2 + NADH + H+
(R)-2-Hydroxyacid + NAD+ <=> 2-Oxo acid + NADH + H+
tRNA adenine + H2O <=> tRNA hypoxanthine + Ammonia
Norsolorinic acid anthrone + Oxygen <=> Norsolorinic acid + H2O
Lariciresinol + NADP+ <=> (+)-Pinoresinol + NADPH + H+
Secoisolariciresinol + NADP+ <=> Lariciresinol + NADPH + H+
(-)-Lariciresinol + NADP+ <=> (-)-Pinoresinol + NADPH + H+
(+)-Secoisolariciresinol + NADP+ <=> (-)-Lariciresinol + NADPH + H+
Agroclavine + NADP+ <=> 6,8-Dimethyl-6,7,8,9-tetradehydroergoline + NADPH + H+
tRNA(Ala) adenine + H2O <=> tRNA(Ala) hypoxanthine + Ammonia
tRNA cytosine + H2O <=> tRNA uridine + Ammonia
dIDP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Orthophosphate
p-Coumaroyl-D-glucose + Cyanidin 3-O-(6''-glucosyl-2''-xylosylgalactoside) <=> beta-D-Glucose + Cyanidin 3-O-[6-O-(6-O-4-hydroxycinnamoyl-beta-D-glucosyl)-2-O-beta-D-xylosyl-beta-D-galactoside]
p-Coumaroyl-CoA + Anthocyanidin 3-O-beta-D-glucoside <=> CoA + Anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside]
UDP-alpha-D-galactose + Cyanidin <=> UDP + Cyanidin 3-O-galactoside
Copal-8-ol diphosphate + H2O <=> Sclareol + Diphosphate
5alpha-Androstane-3,17-dione + NADP+ <=> Androstenedione + NADPH + H+
Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
Purine deoxyribonucleoside + Orthophosphate <=> Purine + 2-Deoxy-D-ribose 1-phosphate
Iminoglycine + H2O <=> Glyoxylate + Ammonia
1-Deoxy-D-xylulose 5-phosphate + Iminoglycine + Thiocarboxy-[sulfur-carrier protein] <=> 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + Sulfur-carrier protein + 2 H2O
Coniferyl acetate + NADPH + H+ <=> Eugenol + NADP+ + Acetate
Coumaryl acetate + NADPH + H+ <=> Chavicol + NADP+ + Acetate
Eugenol + S-Adenosyl-L-methionine <=> Methyleugenol + S-Adenosyl-L-homocysteine
Chavicol + S-Adenosyl-L-methionine <=> Estragole + S-Adenosyl-L-homocysteine
Isochavicol + S-Adenosyl-L-methionine <=> Anethole + S-Adenosyl-L-homocysteine
Coniferyl alcohol + Acetyl-CoA <=> Coniferyl acetate + CoA
4-Coumaryl alcohol + Acetyl-CoA <=> Coumaryl acetate + CoA
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol + L-Serine <=> CMP + 2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
UDP-D-xylose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin 3-O-beta-D-sambubioside
UDP-D-xylose + Cyanidin 3-O-galactoside <=> UDP + Cyanidin 3-O-(beta-D-xylosyl-(1->2)-beta-D-galactoside)
1-O-Vanilloyl-beta-D-glucose + Cyanidin 3-O-glucoside <=> Vanillate + Cyanidin 3,7-di-O-beta-D-glucoside
1-O-Sinapoyl-beta-D-glucose + Cyanidin 3-O-glucoside <=> Sinapate + Cyanidin 3,5-O-diglucoside
UDP-glucose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin-3,5-diglucoside
UDP-glucose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin 3-O-sophoroside
UDP-glucose + Anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] <=> UDP + Anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside
UDP-glucose + Anthocyanidin 3-O-beta-D-sambubioside <=> UDP + Anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside
UDP-N-acetyl-alpha-D-glucosamine <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + H2O
ADP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> AMP + Orthophosphate + NADH
ADP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> AMP + Orthophosphate + NADPH
Sporulenol <=> Tetraprenyl-beta-curcumene + H2O
5-Phosphooxy-L-lysine + H2O <=> L-2-Aminoadipate 6-semialdehyde + Ammonia + Orthophosphate
trans,trans-Farnesyl diphosphate <=> Delta6-Protoilludene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-alpha-Isocomene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (E)-2-epi-beta-Caryophyllene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-epi-alpha-Bisabolol + Diphosphate
trans,trans-Farnesyl diphosphate <=> Valerena-4,7(11)-diene + Diphosphate
Copal-8-ol diphosphate <=> cis-Abienol + Diphosphate
L-Lysine <=> L-Pipecolate + Ammonia
3,5,7-Trioxododecanoyl-CoA <=> CoA + 2,4-Dihydroxy-6-pentylbenzoate
dTDP-6-deoxy-beta-L-talose <=> dTDP-L-rhamnose
(6R)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide
(6R)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate
beta-Carotene <=> 9-cis-beta-Carotene
(4S)-4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate
2-cis,6-cis-Farnesyl diphosphate <=> 7-Epizingiberene + Diphosphate
Choline <=> Trimethylamine + Acetaldehyde + H+
L-Phenylalanine <=> L-beta-Phenylalanine
L-Phenylalanine <=> D-beta-Phenylalanine
ATP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> ADP + Orthophosphate + NADPH
Coumaryl acetate + NADPH + H+ <=> Isochavicol + Acetate + NADP+
Pelargonidin 3-O-glucoside + UDP-D-xylose <=> Pelargonidin 3-O-beta-D-sambubioside + UDP
Cyanidin 3-O-glucoside + UDP-D-xylose <=> Cyanidin 3-O-beta-D-sambubioside + UDP
Delphinidin 3-O-glucoside + UDP-D-xylose <=> Delphinidin 3-O-beta-D-sambubioside + UDP
Pelargonidin 3-O-beta-D-sambubioside + UDP-glucose <=> Pelargonidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP
Cyanidin 3-O-beta-D-sambubioside + UDP-glucose <=> Cyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP
Delphinidin 3-O-beta-D-sambubioside + UDP-glucose <=> Delphinidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP
1-O-Vanilloyl-beta-D-glucose + Pelargonidin 3-O-glucoside <=> Vanillate + Pelargonidin 3,7-di-O-beta-D-glucoside
1-O-Vanilloyl-beta-D-glucose + Delphinidin 3-O-glucoside <=> Vanillate + Delphinidin 3,7-di-O-beta-D-glucoside
Pelargonidin 3-O-glucoside + 1-O-Sinapoyl-beta-D-glucose <=> Pelargonin + Sinapate
Delphinidin 3-O-glucoside + 1-O-Sinapoyl-beta-D-glucose <=> Delphinidin 3,5-diglucoside + Sinapate
S-(Hydroxymethyl)mycothiol + NAD+ + H2O <=> Formate + Mycothiol + NADH + H+
Formaldehyde + Mycothiol <=> S-(Hydroxymethyl)mycothiol
2,4-Diacetamido-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> N,N'-Diacetyllegionaminate + Orthophosphate
O-Acetyl-L-serine + L-Homocysteine <=> L-Cystathionine + Acetate
3 S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> 3 S-Adenosyl-L-homocysteine + Peptide diphthine
S-Adenosyl-L-methionine + Dihydrosterigmatocystin <=> S-Adenosyl-L-homocysteine + Dihydro-O-methylsterigmatocystin
Geraniol + NAD+ <=> Geranial + NADH + H+
(1'S)-Averantin + NADP+ <=> Norsolorinic acid + NADPH + H+
(1'S,5'S)-5'-Hydroxyaverantin + NAD+ <=> 5'-Oxoaverantin + NADH + H+
(1'S,5'R)-5'-Hydroxyaverantin + NAD+ <=> 5'-Oxoaverantin + NADH + H+
Kanamycin B + 2-Oxoglutarate + Oxygen <=> 2'-Dehydrokanamycin A + Succinate + Ammonia + CO2
Cyclo(L-leucyl-L-phenylalanyl) + Oxygen <=> Cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + Hydrogen peroxide
Cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + Oxygen <=> Albonoursin + Hydrogen peroxide
Cyclo(L-leucyl-L-phenylalanyl) + 2 Oxygen <=> Albonoursin + 2 Hydrogen peroxide
5,6,7,8-Tetrahydromethanopterin + NAD+ <=> 7,8-Dihydromethanopterin + NADH + H+
S,S-Dimethyl-beta-propiothetin + Tetrahydrofolate <=> 3-(Methylthio)propanoate + 5-Methyltetrahydrofolate
5-Phospho-alpha-D-ribose 1-diphosphate + 4-Aminobenzoate <=> 4-(beta-D-Ribofuranosyl)aniline 5'-phosphate + CO2 + Diphosphate
S-Adenosylmethioninamine + Agmatine <=> 5'-Methylthioadenosine + N1-(3-Aminopropyl)agmatine
6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-(beta-D-Ribofuranosyl)aniline 5'-phosphate <=> N-[(7,8-Dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + Diphosphate
Dimethylallyl diphosphate + Brevianamide F <=> Diphosphate + Tryprostatin B
Dimethylallyl diphosphate + Verruculogen <=> Diphosphate + Fumitremorgin A
2 ATP <=> 2 Diphosphate + Cyclic di-3',5'-adenylate
Succinyl-CoA + Acetate <=> Acetyl-CoA + Succinate
7,8-Dihydroneopterin 2',3'-cyclic phosphate + H2O <=> Dihydroneopterin phosphate
7,8-Dihydroneopterin 2',3'-cyclic phosphate + H2O <=> 7,8-Dihydroneopterin 2'-phosphate
beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O <=> 2 beta-L-Arabinofuranose
N1-(3-Aminopropyl)agmatine + H2O <=> Spermidine + Urea
GTP + H2O <=> 7,8-Dihydroneopterin 2',3'-cyclic phosphate + Formate + Diphosphate
Geranylgeranyl diphosphate + Indoleglycerol phosphate <=> 3-Geranylgeranylindole + D-Glyceraldehyde 3-phosphate + Diphosphate
3-Geranylgeranylindole + Oxygen + NADPH + H+ <=> 10,11-Epoxy-3-geranylgeranylindole + NADP+ + H2O
Emindole SB + Oxygen + NADPH + H+ <=> 14,15-Epoxyemindole SB + NADP+ + H2O
10,11-Epoxy-3-geranylgeranylindole <=> Emindole SB
14,15-Epoxyemindole SB <=> Paspaline
Paspaline B + NADPH + H+ + Oxygen <=> 12-Demethyl-11,12-dehydropaspaline + NADP+ + H2O + Formate
12-Demethyl-11,12-dehydropaspaline + Oxygen + NADPH + H+ <=> beta-PC-M6 + NADP+ + H2O
beta-PC-M6 + Oxygen + NADPH + H+ <=> 13-Desoxypaxilline + NADP+ + 2 H2O
13-Desoxypaxilline + NADPH + H+ + Oxygen <=> Paxilline + NADP+ + H2O
Paxilline + 2 Dimethylallyl diphosphate <=> 21,22-Diprenylpaxilline + 2 Diphosphate
13-Desoxypaxilline + NADPH + Oxygen + H+ <=> Paspalicine + NADP+ + 2 H2O
Paspalicine + Oxygen + NADPH + H+ <=> Paspalinine + NADP+ + H2O
Paspalinine + Dimethylallyl diphosphate <=> Aflatrem + Diphosphate
13-Desoxyterpendole I + NADPH + H+ + Oxygen <=> Terpendole I + NADP+ + H2O
Terpendole I + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole I + 2 Diphosphate
Lolitriol + Dimethylallyl diphosphate <=> Lolitrem E + Diphosphate
Paspaline B <=> Terpendole G
Paspaline + Oxygen + NADPH + H+ <=> Terpendole E + NADP+ + H2O
Terpendole I + Dimethylallyl diphosphate <=> Terpendole J + Diphosphate
Terpendole J + NADPH + Oxygen + H+ <=> Terpendole C + NADP+ + 2 H2O
Terpendole C <=> Terpendole K
Terpendole C + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole C + 2 Diphosphate
Terpendole J + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole J + 2 Diphosphate
Methyl-Co(III) corrinoid protein + Tetrahydrosarcinapterin <=> Co(I) corrinoid protein + 5-Methyl-H4SPT
(R)-(Homo)2-citrate <=> (-)-threo-Iso(homo)2-citrate
(R)-(Homo)2-citrate <=> cis-(Homo)2-aconitate + H2O
cis-(Homo)2-aconitate + H2O <=> (-)-threo-Iso(homo)2-citrate
(R)-(Homo)3-citrate <=> (-)-threo-Iso(homo)3-citrate
(R)-(Homo)3-citrate <=> cis-(Homo)3-aconitate + H2O
cis-(Homo)3-aconitate + H2O <=> (-)-threo-Iso(homo)3-citrate
7-Oxoheptanoic acid <=> 7-Mercaptoheptanoic acid
Versiconol acetate + H2O <=> Versiconol + Acetate
Versiconol acetate + NADP+ <=> Versiconal hemiacetal acetate + NADPH + H+
Versiconol + NADP+ <=> Versiconal + NADPH + H+
Versiconal hemiacetal acetate + H2O <=> Versiconal + Acetate
Versiconal <=> Versicolorin B + H2O
S-Adenosyl-L-methionine + Dihydrodemethylsterigmatocystin <=> S-Adenosyl-L-homocysteine + Dihydrosterigmatocystin
S-Adenosyl-L-methionine <=> S-Adenosyl-L-homocysteine
Terpendole E <=> Terpendole G
Terpendole G <=> Terpendole B
2-Amino-2-deoxy-D-gluconate + Protein N(pi)-phospho-L-histidine <=> D-Glucosaminate-6-phosphate + Protein histidine
D-Glucosaminate-6-phosphate <=> 2-Dehydro-3-deoxy-6-phospho-D-gluconate + Ammonia
beta-Paxitriol <=> Paxilline
(2E,6E)-Farnesol + NAD+ <=> 2-trans,6-trans-Farnesal + NADH + H+
L-Enduracididine + 2-Oxoglutarate + Oxygen <=> (3S)-3-Hydroxy-L-enduracididine + Succinate + CO2
(3S,5S)-Carbapenam-3-carboxylic acid + 2-Oxoglutarate + Oxygen <=> (5R)-Carbapen-2-em-3-carboxylate + Succinate + CO2 + H2O
Kanamycin A + NADP+ <=> 2'-Dehydrokanamycin A + NADPH + H+
(S)-2-Chloropropanoate + NADP+ <=> 2-Chloroacrylate + NADPH + H+
Hydrogen sulfide + NAD+ <=> Sulfur + NADH + H+
GDP-beta-L-colitose + NAD+ <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADH + H+
GDP-beta-L-colitose + NADP+ <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADPH + H+
3alpha-Hydroxysteroid + NAD+ <=> 3-Oxosteroid + NADH + H+
3alpha-Hydroxysteroid + NADP+ <=> 3-Oxosteroid + NADPH + H+
UDP-kanosamine + 2'-Deamino-2'-hydroxyneamine <=> UDP + Kanamycin A
UDP-kanosamine + Neamine <=> UDP + Kanamycin B
UDP-kanosamine + Paromamine <=> UDP + Kanamycin C
UDP-kanosamine + 2'-Deamino-2'-hydroxyparomamine <=> UDP + Kanamycin X
S-Methyl-L-methionine + L-Selenocysteine <=> L-Methionine + Se-Methyl-L-selenocysteine
S-Adenosyl-L-methionine + Phenylpyruvate <=> S-Adenosyl-L-homocysteine + (3S)-2-Oxo-3-phenylbutanoate
UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
UDP-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glc-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
UDP-N-acetyl-D-galactosamine + N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol <=> UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
UDP-alpha-D-galactose + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol <=> UDP + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
S-Adenosyl-L-methionine + 7-(Hydroxymethyl)bacteriochlorophyllide c + H2O <=> 7-(Dihydroxymethyl)bacteriochlorophyllide c + 5'-Deoxyadenosine + L-Methionine
Hydrogen sulfide + NADP+ <=> Sulfur + NADPH + H+
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + L-Serine <=> CMP + 2,3-Bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine
NDP + H2O <=> Nucleoside 5'-phosphate + Orthophosphate
Nucleoside triphosphate + 2 H2O <=> Nucleoside 5'-phosphate + 2 Orthophosphate
2 Caldariellaquinol + Oxygen + n H+ <=> 2 Caldariellaquinone + 2 H2O + n H+
L-Asparagine + 2-Oxoglutarate + Oxygen <=> (2S,3S)-3-Hydroxyasparagine + Succinate + CO2
S-Adenosyl-L-methionine + Benzoate <=> S-Adenosyl-L-homocysteine + Methyl benzoate
S-Adenosyl-L-methionine + Salicylate <=> S-Adenosyl-L-homocysteine + Methyl salicylate
S-Adenosyl-L-methionine + Gibberellin A9 <=> S-Adenosyl-L-homocysteine + Methyl gibberellin A9
S-Adenosyl-L-methionine + Gibberellin A4 <=> S-Adenosyl-L-homocysteine + Methyl gibberellin A4
S-Adenosyl-L-methionine + Anthranilate <=> S-Adenosyl-L-homocysteine + O-Methyl anthranilate
S-Adenosyl-L-methionine + Indole-3-acetate <=> S-Adenosyl-L-homocysteine + Methyl (indol-3-yl)acetate
ATP + 3-Dimethylallyl-4-hydroxybenzoate + 3-Amino-4,7-dihydroxycoumarin <=> AMP + Diphosphate + 8-Demethylnovobiocic acid
S-Adenosyl-L-methionine + 8-Demethylnovobiocic acid <=> S-Adenosyl-L-homocysteine + Novobiocic acid
S-Adenosyl-L-methionine + L-Histidine-[translation elongation factor 2] <=> 5'-Methylthioadenosine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine
Dimethylallyl diphosphate + Brevianamide F <=> Diphosphate + Deoxybrevianamide E
Dimethylallyl diphosphate + 12alpha,13alpha-Dihydroxyfumitremorgin C <=> Diphosphate + Fumitremorgin B
dTDP-4-oxo-5-C-methyl-L-rhamnose + NADH + H+ <=> dTDP-5-dimethyl-L-lyxose + NAD+
GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate <=> GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate
O-Acetyl-L-serine + Hydroxyurea <=> O-Ureido-L-serine + Acetate
ATP + GTP <=> 2 Diphosphate + Cyclic GMP-AMP
L-Threonine + ATP + HCO3- + H+ <=> L-Threonylcarbamoyladenylate + Diphosphate + H2O
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + 1D-myo-Inositol 3-phosphate <=> CMP + 1-Archaetidyl-1D-myo-inositol 3-phosphate
UDP-N-acetyl-D-galactosamine + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
N(omega)-Hydroxyarginine + H2O <=> L-Ornithine + Hydroxyurea
2-Heptyl-4(1H)-quinolone + NADH + H+ + Oxygen <=> 2-Heptyl-3-hydroxy-quinolone + NAD+ + H2O
2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate <=> 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O
O-Ureido-D-serine + ATP + H2O <=> Cycloserine + CO2 + Ammonia + ADP + Orthophosphate
S-Adenosyl-L-methionine + Emodin <=> S-Adenosyl-L-homocysteine + Questin
Acetyl-CoA + Benzyl alcohol <=> CoA + Benzyl acetate
Acetyl-CoA + Cinnamyl alcohol <=> CoA + Cinnamyl acetate
5'-Oxoaverantin <=> (1'S,5'S)-Averufin + H2O
(1'S,5'S)-Averufin + NADPH + H+ + Oxygen <=> 1'-Hydroxyversicolorone + NADP+ + H2O
1'-Hydroxyversicolorone + NADPH + H+ + Oxygen <=> Versiconal hemiacetal acetate + NADP+ + H2O
Versicolorone + NADPH + H+ + Oxygen <=> Versiconol acetate + NADP+ + H2O
Versicolorin B + Oxygen + NADPH + H+ <=> Versicolorin A + NADP+ + 2 H2O
Versicolorin B <=> Dihydrodemethylsterigmatocystin
Versicolorin A <=> 6-Demethylsterigmatocystin
Dihydro-O-methylsterigmatocystin <=> Aflatoxin G2
O-Methylsterigmatocystin <=> Aflatoxin G1
Palmitoyl-CoA + [Protein]-L-cysteine <=> S-Palmitoylprotein + CoA
Malonyl-CoA + (S)-1-Pyrroline-5-carboxylate + H2O <=> CoA + (2S,5S)-trans-Carboxymethylproline + CO2
Maltose 6'-phosphate + H2O <=> Maltose + Orthophosphate
(S)-(2,4-Dichlorophenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Pyruvate + Succinate + CO2
O-Ureido-L-serine <=> O-Ureido-D-serine
S-Adenosyl-L-methionine + gamma-Tocotrienol <=> S-Adenosyl-L-homocysteine + alpha-Tocotrienol
S-Adenosyl-L-methionine + delta-Tocotrienol <=> S-Adenosyl-L-homocysteine + beta-Tocotrienol
trans,trans-Farnesyl diphosphate + H2O <=> Kunzeaol + Diphosphate
6-Tuliposide A <=> Tulipalin A + D-Glucose
2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine <=> Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine
ATP + Agmatine + [tRNA(Ile2)]-cytidine34 + H2O <=> [tRNA(Ile2)]-2-agmatinylcytidine34 + AMP + 2 Orthophosphate
S-Adenosyl-L-methionine + Adenine in rRNA <=> S-Adenosyl-L-homocysteine + N1-Methyladenine in rRNA
S-Adenosyl-L-methionine + 7-[(3S)-3-Amino-3-carboxypropyl]-4-demethylwyosine in tRNA(Phe) <=> S-Adenosyl-L-homocysteine + 7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe)
L-Phenylalanine + 2-Oxo acid <=> Phenylpyruvate + L-Amino acid
Phenylpyruvate + Acetyl-CoA + H2O <=> 2-Benzylmalic acid + CoA
2-Benzylmalic acid <=> 3-Benzylmalic acid
3-Benzylmalic acid + NAD+ <=> 2-Oxo-4-phenylbutyric acid + CO2 + NADH + H+
2-Oxo-4-phenylbutyric acid + L-Amino acid <=> L-Homophenylalanine + 2-Oxo acid
meso-2,3-Butanediol + NAD+ <=> (S)-Acetoin + NADH + H+
meso-2,3-Butanediol + NAD+ <=> (R)-Acetoin + NADH + H+
L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2
3,4-Dehydrolycopene <=> Torulene
Geranyl diphosphate <=> (-)-Bornyl diphosphate
Hydrogen sulfide + Polysulfide(n) + NADP+ <=> Polysulfide(n+1) + NADPH + H+
Acetyl-CoA + GDP-4-amino-4,6-dideoxy-alpha-D-mannose <=> CoA + GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose
2 NADH + 2 H+ + Oxygen <=> 2 NAD+ + 2 H2O
2 NADPH + 2 H+ + Oxygen <=> 2 NADP+ + 2 H2O
D-Glucose 6-phosphate + NAD+ <=> 3-Dehydro-D-glucose 6-phosphate + NADH + H+
D-Glucose 6-phosphate + NAD+ <=> D-Glucono-1,5-lactone 6-phosphate + NADH + H+
2-Amino-5-chlorophenol + Oxygen <=> 2-Amino-5-chloromuconate 6-semialdehyde
7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + 2-Oxoglutarate + Oxygen <=> 7-(2-Hydroxy-3-amino-3-carboxypropyl)wyosine in tRNA(Phe) + Succinate + CO2
S-Adenosyl-L-methionine + L-Histidine <=> S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine
S-Adenosyl-L-methionine + Nalpha-Methylhistidine <=> S-Adenosyl-L-homocysteine + N,N-Dimethylhistidine
NDP-glucose + D-Glucose <=> alpha,alpha-Trehalose + NDP
3-Methylbutanoyl-CoA + S-Adenosyl-L-methionine <=> CoA + 5'-Methylthioadenosine + N-Isovaleryl-L-homoserine lactone
(S)-2-(4-Chloro-2-methylphenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 4-Chloro-2-methylphenol + Pyruvate + Succinate + CO2
(R)-2-Hydroxyacid + NADP+ <=> 2-Oxo acid + NADPH + H+
p-Coumaroyl-CoA + S-Adenosyl-L-methionine <=> CoA + 5'-Methylthioadenosine + N-(4-Coumaroyl)-L-homoserine lactone
Protodioscin + H2O <=> 26-Deglucoprotodioscin + D-Glucose
ATP + H2O + Tungstate <=> ADP + Orthophosphate + Tungstate
L-Galactonate <=> 2-Dehydro-3-deoxy-L-galactonate + H2O
Geranylgeranyl diphosphate + H2O <=> (E,E)-Geranyllinalool + Diphosphate
Carbon disulfide + H2O <=> Carbonyl sulfide + Hydrogen sulfide
Carbonyl sulfide + H2O <=> CO2 + Hydrogen sulfide
dTDP-D-fucose <=> dTDP-alpha-D-fucofuranose
GTP + RNA 3'-terminal-phosphate <=> GMP + Diphosphate + RNA terminal-2',3'-cyclic-phosphate
Carbon disulfide + 2 H2O <=> CO2 + 2 Hydrogen sulfide
Mecoprop-P + 2-Oxoglutarate + Oxygen <=> 4-Chloro-2-methylphenol + Pyruvate + Succinate + CO2
Carbamoyl phosphate + ATP + H2O <=> Diphosphate + O-Carbamoyladenylate + Orthophosphate
(R)-(2,4-Dichlorophenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Pyruvate + Succinate + CO2
O-Carbamoyladenylate + Tobramycin <=> AMP + Nebramycin 5'
O-Carbamoyladenylate + Kanamycin A <=> AMP + 6''-O-Carbamoylkanamycin A
Aclacinomycin T + H2O <=> 15-Demethylaclacinomycin T + Methanol
7-Methylguanosine 5'-phosphate + H2O <=> N7-Methylguanosine + Orthophosphate
Kanosamine 6-phosphate + H2O <=> Kanosamine + Orthophosphate
ATP + 1-Diphosinositol pentakisphosphate <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Long-chain aldehyde + [Protein]-L-cysteine + NADP+ <=> [Protein]-S-(long-chain-acyl)-L-cysteine + NADPH + H+
2-Dehydro-3-deoxy-L-galactonate <=> Pyruvate + L-Glyceraldehyde
N1-Methylguanine in tRNA(Phe) + Pyruvate + S-Adenosyl-L-methionine <=> 4-Demethylwyosine in tRNA(Phe) + L-Methionine + 5'-Deoxyadenosine + CO2 + H2O
S-Substituted N-acetyl-L-cysteine + H2O <=> S-Substituted L-cysteine + Acetate
N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
D-Ribose 1,5-bisphosphate <=> D-Ribulose 1,5-bisphosphate
ATP + (2S,5S)-trans-Carboxymethylproline <=> AMP + Diphosphate + (3S,5S)-Carbapenam-3-carboxylic acid
9-cis-beta-Carotene + Oxygen <=> 9-cis-10'-Apo-beta-carotenal + beta-Ionone
9-cis-10'-Apo-beta-carotenal + 2 Oxygen <=> Carlactone + (2E,4E,6E)-7-Hydroxy-4-methylhepta-2,4,6-trienal
beta-Carotene + Oxygen <=> all-trans-10'-Apo-beta-carotenal + beta-Ionone
all-trans-10'-Apo-beta-carotenal + Oxygen <=> 13-Apo-beta-carotenone + (2E,4E,6E)-4-Methylocta-2,4,6-trienedial
(R)-5-Phosphomevalonate + ATP <=> Isopentenyl phosphate + ADP + Orthophosphate + CO2
L-Glyceraldehyde + NADPH + H+ <=> Glycerol + NADP+
(S)-5-Amino-3-oxohexanoic acid + Acetyl-CoA <=> L-3-Aminobutyryl-CoA + Acetoacetate
L-Galactonate + NAD+ <=> D-Galacturonate + NADH + H+
beta-Paxitriol <=> Penitrem D
beta-Paxitriol <=> Janthitrem C
12-Demethyl-11,12-dehydropaspaline <=> Terpendole B
Terpendole B <=> 13-Desoxyterpendole I
dTDP-6-deoxy-D-allose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-allose + NADPH + H+
Secondary alcohol + Coenzyme F420 <=> Ketone + Reduced coenzyme F420
(9Z)-Octadecenoic acid + Oxygen <=> (8E,10S)-10-Hydroperoxyoctadeca-8-enoate
Linoleate + Oxygen <=> (8E,10S,12Z)-10-Hydroperoxyoctadeca-8,12-dienoate
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> (8E,10S,12Z,15Z)-10-Hydroperoxyoctadeca-8,12,15-trienoate
4-O-(beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + H2O <=> 4-O-(beta-L-Arabinofuranosyl)-(2S,4S)-4-hydroxyproline + beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranose
Avenacoside B + H2O <=> 26-Desgluco-avenacoside B + D-Glucose
Dioscin + 3 H2O <=> D-Glucose + 2 L-Rhamnose + Diosgenin
Dioscin + 2 H2O <=> 2 L-Rhamnose + Diosgenin 3-O-beta-D-glucopyranoside
Chorismate + H2O <=> (4R,5R)-4,5-Dihydroxycyclohexa-1(6),2-diene-1-carboxylate + Pyruvate
trans,trans-Farnesyl diphosphate <=> alpha-Copaene + Diphosphate
Copalyl diphosphate <=> Miltiradiene + Diphosphate
7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine <=> 7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-homocysteine
7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine + CO2 <=> Wybutosine in tRNA(Phe) + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + 6-Hydroxytryprostatin B <=> S-Adenosyl-L-homocysteine + Tryprostatin A
3-Oxodecanoate + Anthraniloyl-CoA <=> CoA + 2-Heptyl-4(1H)-quinolone + CO2 + H2O
Octanoyl-CoA + L-Cysteinyl-protein <=> S-Octanoyl-L-cysteinyl-protein + CoA
4-Hydroxy-2,5-dimethylfuran-3(2H)-one + NADP+ <=> 4-Hydroxy-5-methyl-2-methylenefuran-3(2H)-one + NADPH + H+
UDP-glucose + Vancomycin aglycone <=> UDP + Desvancosaminyl-vancomycin
dTDP-L-epivancosamine + Desvancosaminyl-vancomycin <=> dTDP + Chloroorienticin B
UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein] <=> UDP + 3-O-[N-Acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein]
Chorismate <=> 3-Hydroxybenzoate + Pyruvate
trans,trans-Farnesyl diphosphate <=> (+)-beta-Chamigrene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Thujopsene + Diphosphate
Acetyl-CoA + Itaconate <=> Acetate + Itaconyl-CoA
2 Reduced coenzyme F420 + Oxygen <=> 2 Coenzyme F420 + 2 H2O
D-Galactono-1,5-lactone + H2O <=> D-Galactonate
(S)-Reticuline + S-Adenosyl-L-methionine <=> (S)-Laudanine + S-Adenosyl-L-homocysteine
(R)-Reticuline + S-Adenosyl-L-methionine <=> (-)-Laudanidine + S-Adenosyl-L-homocysteine
UDP-glucose + Ginsenoside Rd <=> UDP + Ginsenoside Rb1
Nicotinate D-ribonucleotide + Phenol <=> Nicotinate + Phenyl 5-phospho-alpha-D-ribofuranoside + H+
UDP-D-xylose + Kaempferol <=> UDP + Kaempferol 3-O-beta-D-xyloside
O-Phospho-L-serine + Thiocarboxy-[sulfur-carrier protein] <=> [Sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + Orthophosphate
S-Adenosyl-L-methionine + 4-Demethylwyosine in tRNA(Phe) <=> 5'-Methylthioadenosine + 7-[(3S)-3-Amino-3-carboxypropyl]-4-demethylwyosine in tRNA(Phe)
L-Malyl-CoA + H2O <=> (S)-Malate + CoA
FAD + [Protein]-L-threonine <=> [Protein]-FMN-L-Threonine + AMP
Acetyl-CoA + Oxalate <=> Acetate + Oxalyl-CoA
D-Glyceraldehyde + NADP+ + H2O <=> D-Glycerate + NADPH + H+
2-Dehydro-3-deoxy-D-galactonate <=> Pyruvate + D-Glyceraldehyde
Mycothiol S-conjugate + H2O <=> S-Substituted N-acetyl-L-cysteine + 1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol
D-Galactose <=> alpha-D-Galactose
3-O-[N-Acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-D-galactosamine <=> 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP
N-Acyl-aromatic-L-amino acid + H2O <=> Aromatic amino acid + Carboxylate
alpha-D-Galactose 1-phosphate + H2O <=> D-Galactose + Orthophosphate
delta-Tocotrienol <=> 6-Geranylgeranyl-2-methylbenzene-1,4-diol
gamma-Tocotrienol <=> 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol
NAD+ <=> Cyclic ADP-ribose + Nicotinamide + H+
Cyclic ADP-ribose + H2O <=> ADP-ribose
NADP+ <=> 2'-Phospho-cyclic ADP-ribose + Nicotinamide + H+
2'-Phospho-cyclic ADP-ribose + Nicotinate + H+ <=> Nicotinic acid adenine dinucleotide phosphate
NAD+ + Histone N6-acetyl-L-lysine + H2O <=> Nicotinamide + Histone-L-lysine + O-Acetyl-ADP-ribose + H+
NAD+ + Protein N6-acetyl-L-lysine + H2O <=> Nicotinamide + Protein lysine + O-Acetyl-ADP-ribose + H+
alpha-NADH + H+ + Oxygen <=> NAD+ + Hydrogen peroxide
alpha-NADPH + H+ + Oxygen <=> NADP+ + Hydrogen peroxide
(Z)-Phenylacetaldehyde oxime + NADPH + Oxygen + H+ <=> Mandelonitrile + NADP+ + 2 H2O
Mandelonitrile + UDP-glucose <=> Prunasin + UDP
Prunasin + UDP-glucose <=> Amygdalin + UDP
Succinyl-CoA + (R)-2-Methylmalate <=> Succinate + (3R)-Citramalyl-CoA
Succinyl-CoA + (R)-Malate <=> Succinate + (R)-Malyl-CoA
(E)-4-(Trimethylammonio)but-2-enoyl-CoA + L-Carnitine <=> (E)-4-(Trimethylammonio)but-2-enoate + L-Carnitinyl-CoA
4-Trimethylammoniobutanoyl-CoA + L-Carnitine <=> 4-Trimethylammoniobutanoate + L-Carnitinyl-CoA
2-Thio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-methionine <=> 2-Methylthio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-homocysteine
L-Threonylcarbamoyladenylate + tRNA adenine <=> AMP + N6-L-Threonylcarbamoyladenine in tRNA
2-Thio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-methionine <=> 2-Methylthio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-homocysteine
[Ribosomal protein S12]-3-thioaspartate + S-Adenosyl-L-methionine <=> [Ribosomal protein S12]-3-methylthioaspartate + S-Adenosyl-L-homocysteine
3'-Phosphoadenylyl sulfate + Desulfo-A47934 <=> Adenosine 3',5'-bisphosphate + A47934
CTP + Phytol <=> CDP + Phytyl phosphate
Fumarate + Coenzyme M + Coenzyme B <=> Succinate + Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide
L-Tryptophan + L-Proline + 2 ATP <=> Brevianamide F + 2 AMP + 2 Diphosphate
dTDP-beta-L-evernosamine + NADPH + H+ + Oxygen <=> dTDP-N-hydroxy-beta-L-evernosamine + NADP+ + H2O
dTDP-N-hydroxy-beta-L-evernosamine + NADPH + H+ + Oxygen <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + NADP+ + 2 H2O
UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + NADPH + H+
Chorismate <=> 3-[(1-Carboxyvinyl)oxy]benzoate + H2O
S-Adenosyl-L-methionine + 3-[(1-Carboxyvinyl)oxy]benzoate + H2O <=> 6-Amino-6-deoxyfutalosine + L-Methionine + HCO3-
6-Amino-6-deoxyfutalosine + H2O <=> Dehypoxanthine futalosine + Adenine
(E)-Phenylacetaldoxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
(E)-4-Hydroxyphenylacetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate <=> Glycerone phosphate + L-Aspartate 4-semialdehyde
(3R)-Citramalyl-CoA <=> Acetyl-CoA + Pyruvate
L-Carnitinyl-CoA <=> (E)-4-(Trimethylammonio)but-2-enoyl-CoA + H2O
UDP-2-acetamido-2,6-dideoxy-beta-L-talose <=> UDP-N-acetyl-beta-L-fucosamine
ATP + Citrate + L-Glutamate <=> ADP + Orthophosphate + beta-Citryl-L-glutamate
ATP + N-Acetyl-L-aspartate + L-Glutamate <=> ADP + Orthophosphate + N-Acetylaspartylglutamate
2 ATP + N-Acetyl-L-aspartate + 2 L-Glutamate <=> 2 ADP + 2 Orthophosphate + N-Acetylaspartylglutamylglutamate
S-Adenosyl-L-methionine + (+/-)-Pavine <=> S-Adenosyl-L-homocysteine + N-Methylpavine
Anthraniloyl-CoA + Methanol <=> CoA + O-Methyl anthranilate
NAD+ + Glycine + [Protein]-L-cysteine <=> ADP-5-ethyl-4-methylthiazole-2-carboxylate + Nicotinamide + [Protein]-dehydroalanine + 3 H2O
Pyridoxal phosphate + L-Histidine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine
N-Acetylaspartylglutamate + H2O <=> N-Acetyl-L-aspartate + L-Glutamate
N-Acetylaspartylglutamylglutamate + H2O <=> N-Acetylaspartylglutamate + L-Glutamate
L-Fucono-1,5-lactone + H2O <=> L-Fuconate
2-Dehydro-3-deoxy-L-fuconate + NAD+ <=> 2,4-Diketo-3-deoxy-L-fuconate + NADH + H+
2,4-Diketo-3-deoxy-L-fuconate + H2O <=> (S)-Lactate + Pyruvate
ATP + N-Acetylaspartylglutamate + L-Glutamate <=> ADP + Orthophosphate + N-Acetylaspartylglutamylglutamate
6-Amino-6-deoxyfutalosine + H2O <=> Futalosine + Ammonia
6-Oxocyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA
(S)-2-Phenyloxirane <=> Phenylacetaldehyde
Kanosamine 6-phosphate + 2-Oxoglutarate <=> 3-Dehydro-D-glucose 6-phosphate + L-Glutamate
L-Lysine + 8-Amino-7-oxononanoate <=> L-2-Aminoadipate 6-semialdehyde + 7,8-Diaminononanoate
Hexadecanoyl-[acp] + CoA <=> Palmitoyl-CoA + Acyl-carrier protein
5-O-Caffeoylshikimic acid + H2O <=> Caffeate + Shikimate
Propane + NADH + H+ + Oxygen <=> Propan-2-ol + NAD+ + H2O
Propan-2-ol + NAD+ <=> Acetone + NADH + H+
Acetone + NADPH + H+ + Oxygen <=> Methyl acetate + NADP+ + H2O
Methyl acetate + H2O <=> Acetate + Methanol
Acetyl-CoA + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CoA + CO2
Geranylgeranyl diphosphate + Homogentisate <=> Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2
S-Adenosyl-L-methionine + 2-Methyl-6-solanyl-1,4-benzoquinol <=> S-Adenosyl-L-homocysteine + Plastoquinol-9
S-Adenosyl-L-methionine + 6-Geranylgeranyl-2-methylbenzene-1,4-diol <=> S-Adenosyl-L-homocysteine + 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol
ADP-5-ethyl-4-methylthiazole-2-carboxylate + H2O <=> 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate + AMP
4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate <=> Thiamin monophosphate + Diphosphate + CO2
cis-Dec-3-enoyl-[acp] <=> n-7 Unsaturated acyl-[acyl-carrier protein]
(S)-Lactaldehyde + NAD+ <=> Methylglyoxal + NADH + H+
2 S-Adenosyl-L-methionine + Adenine in rRNA <=> 2 S-Adenosyl-L-homocysteine + N6-Dimethyladenine in rRNA
Propane-1,2-diol + NAD+ <=> Hydroxyacetone + NADH + H+
Methylglyoxal + NADH + H+ <=> Hydroxyacetone + NAD+
(2S)-2,3-Dihydroxypropane-1-sulfonate + NAD+ <=> (2S)-3-Sulfolactaldehyde + NADH + H+
2 3-Amino-4-hydroxybenzoate + Acetylcysteine + 2 Oxygen <=> Grixazone B + 4 H2O + CO2
3-Methyl-L-tyrosine + Hydrogen peroxide <=> 3-Hydroxy-5-methyl-L-tyrosine + H2O
(2-Amino-1-hydroxyethyl)phosphonate + Oxygen <=> Glycine + Orthophosphate
L-Isoleucine + 2-Oxoglutarate + Oxygen <=> (4S)-4-Hydroxy-L-isoleucine + Succinate + CO2
2-Aminoethylphosphonate + 2-Oxoglutarate + Oxygen <=> (2-Amino-1-hydroxyethyl)phosphonate + Succinate + CO2
5-Methyl-1-naphthoate + NADPH + H+ + Oxygen <=> 3-Hydroxy-5-methyl-1-naphthoate + NADP+ + H2O
trans,trans-Farnesyl diphosphate <=> alpha-Longipinene + Diphosphate
Miltiradiene <=> Abieta-8,11,13-triene
L-Phenylalanine + Tetrahydrobiopterin + Oxygen <=> 3-Hydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin
(R)-2-Methylpyrrolidine + NADP+ <=> 2-Methyl-1-pyrroline + NADPH + H+
(S)-3-Chloro-beta-tyrosyl-[pcp] + FADH2 + Oxygen <=> (S)-3-Chloro-4,5-dihydroxy-beta-phenylalanyl-[pcp] + FAD + H2O
trans,trans-Farnesyl diphosphate <=> (-)-exo-alpha-Bergamotene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-alpha-Santalene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Santalene + Diphosphate
OA-6129 A + 2-Oxoglutarate + Oxygen <=> OA-6129 B2 + Succinate + CO2
(5R)-Carbapen-2-em-3-carboxylate + L-Cysteine <=> C20817 + CO2
C20817 <=> C20818
C20818 <=> C20819
C20819 <=> 2,3-Dihydrothienamycin
2,3-Dihydrothienamycin + 2-Oxoglutarate + Oxygen <=> Thienamycin + Succinate + CO2 + H2O
Epithienamycin F + 2-Oxoglutarate + Oxygen <=> Epithienamycin E + Succinate + CO2 + H2O
Epithienamycin E + 2-Oxoglutarate + Oxygen <=> MM 4550 + Succinate + CO2
C20819 <=> 8-Dehydroxythienamycin
8-Dehydroxythienamycin <=> Thienamycin
Acetyl-CoA + Thienamycin <=> CoA + N-Acetylthienamycin
Acetyl-CoA + Deacetylepithienamycin F <=> CoA + Epithienamycin F
CoA + H2O <=> Pantetheine 4'-phosphate + Adenosine 3',5'-bisphosphate
Pantetheine 4'-phosphate + H2O <=> Pantetheine + Orthophosphate
C20821 + Pantetheine <=> OA-6129 A
OA-6129 B2 <=> OA-6129 B1
3'-Phosphoadenylyl sulfate + OA-6129 B1 <=> Adenosine 3',5'-bisphosphate + OA-6129 C
OA-6129 C + H2O <=> Deacetylepithienamycin F + Pantothenate
C20818 <=> C20822
C20822 <=> C20823
C20823 <=> C20819
C20822 <=> Northienamycin
all-trans-Polyprenyl diphosphate + 1,4-Dihydroxy-2-naphthoate <=> Demethylmenaquinol + Diphosphate + CO2
4-Hydroxybutanoic acid + ATP + CoA <=> 4-Hydroxybutyryl-CoA + ADP + Orthophosphate
3-Hydroxyisovaleryl-CoA <=> 3-Hydroxyisovalerate
6-Deoxy-6-sulfo-D-fructose 1-phosphate <=> Glycerone phosphate + (2S)-3-Sulfolactaldehyde
all-trans-Pentaprenyl diphosphate + H2O <=> Ophiobolin F + Diphosphate
Geranylgeranyl diphosphate + H2O <=> Cyclooctat-9-en-7-ol + Diphosphate
alpha-L-Fucopyranose <=> beta-L-Fucopyranose
6-Sulfo-beta-D-quinovose <=> 6-Deoxy-6-sulfo-D-fructose
Tobramycin + Carbamoyl phosphate + ATP + H2O <=> Nebramycin 5' + AMP + Diphosphate + Orthophosphate
Kanamycin A + Carbamoyl phosphate + ATP + H2O <=> 6''-O-Carbamoylkanamycin A + AMP + Diphosphate + Orthophosphate
ATP + 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + CoA <=> AMP + Diphosphate + 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA
ATP + Delta4-Dafachronic acid + CoA <=> AMP + Diphosphate + (25S)-3-Oxocholest-4-en-26-oyl-CoA
ATP + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoate + CoA <=> AMP + Diphosphate + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
ATP + L-Glutamate + Aniline <=> ADP + Orthophosphate + N5-Phenyl-L-glutamine
2-Amino-2-deoxy-D-gluconate <=> (2Z,4S,5R)-2-Amino-4,5,6-trihydroxyhex-2-enoate + H2O
(2Z,4S,5R)-2-Amino-4,5,6-trihydroxyhex-2-enoate <=> (4S,5R)-4,5,6-Trihydroxy-2-iminohexanoate
(4S,5R)-4,5,6-Trihydroxy-2-iminohexanoate + H2O <=> 2-Dehydro-3-deoxy-D-gluconate + Ammonia
Deoxynucleoside 5'-phosphate + H2O <=> Deoxynucleoside + Orthophosphate
5-Methylbarbiturate + H2O <=> 3-Oxo-3-ureidoisobutyrate
3-Oxo-3-ureidoisobutyrate + H2O <=> Methylmalonate + Urea
(R)-Mevalonate + ATP <=> (R)-Mevalonate 3-phosphate + ADP
(R)-Mevalonate 3-phosphate + ATP <=> (R)-Mevalonate 3,5-bisphosphate + ADP
(R)-Mevalonate 3,5-bisphosphate <=> Isopentenyl phosphate + CO2 + Orthophosphate
4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O
3-Hexenal + NADH + H+ <=> 3-Hexenol + NAD+
Levan + H2O <=> Levan + Levanbiose
UDP-N-acetyl-alpha-D-glucosamine + NAD+ <=> UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+
(S)-2-Hydroxyacid + NADP+ <=> 2-Oxo acid + NADPH + H+
L-Arabinose + NADP+ <=> L-Arabinono-1,4-lactone + NADPH + H+
L-Rhamnose + NADP+ <=> L-Rhamnono-1,4-lactone + NADPH + H+
L-Ornithine + NADPH + H+ + Oxygen <=> N5-Hydroxy-L-ornithine + NADP+ + H2O
L-Ornithine + NADH + H+ + Oxygen <=> N5-Hydroxy-L-ornithine + NAD+ + H2O
3alpha-Hydroxy-3,5-dihydromonacolin L acid <=> Monacolin L acid + H2O
Formate + Coenzyme F420 <=> CO2 + Reduced coenzyme F420
Dihydrosanguinarine + NAD+ <=> Sanguinarine + NADH + H+
Dihydrosanguinarine + NADP+ <=> Sanguinarine + NADPH + H+
Dihydrochelirubine + NAD+ <=> Chelirubine + NADH + H+
Dihydrochelirubine + NADP+ <=> Chelirubine + NADPH + H+
1-Alkyl-2-acylglycerol + UDP-alpha-D-galactose <=> Galactosyl-1-alkyl-2-acylglycerol + UDP
3'-Phosphoadenylyl sulfate + Galactosyl-1-alkyl-2-acylglycerol <=> Adenosine 3',5'-bisphosphate + Seminolipid
Protein glutamine + S-Adenosyl-L-methionine <=> Protein N5-methyl-L-glutamine + S-Adenosyl-L-homocysteine
Diglucosyldiacylglycerol + UDP-glucose <=> Triglucosyldiacylglycerol + UDP
Mannobiose + H2O <=> 2 D-Mannose
Mannobiose <=> 4-O-beta-D-Mannopyranosyl-D-glucopyranose
1,4-beta-D-Mannooligosaccharide(n) + (n-2) Orthophosphate <=> Mannobiose + (n-2) D-Mannose 1-phosphate
S-Adenosyl-L-methionine + m7G(5')pppRm-mRNA <=> S-Adenosyl-L-homocysteine + 5'-(N7-Methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(2'-O-methyl-ribonucleotide)-[mRNA]
n Nucleoside triphosphate <=> 5'-Triphospho-[mRNA](n) + (n-1) Diphosphate
5'-Triphospho-[mRNA] + H2O <=> (5')ppPur-mRNA + Orthophosphate
m7G(5')pppR-mRNA + H2O <=> N7-Methylguanosine 5'-diphosphate + 5'-Phospho-[mRNA]
5'-Triphospho-[mRNA] + H2O <=> 5'-Phospho-[mRNA] + Diphosphate
D-Psicose <=> D-Fructose
D-Tagatose <=> D-Sorbose
alpha-L-Rhamnose <=> beta-L-Rhamnose
ATP + 3-(Methylthio)propanoate + CoA <=> AMP + Diphosphate + 3-(Methylthio)propanoyl-CoA
ATP + (R)-Pantoate + beta-Alanine <=> ADP + Orthophosphate + Pantothenate
ADP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Orthophosphate + DNA(n+m)
GTP + DNA(n) + 5'-Phospho-DNA(m) <=> GMP + Diphosphate + DNA(n+m)
S-Adenosyl-L-methionine + 3'-Hydroxyflavone <=> S-Adenosyl-L-homocysteine + 3'-Methoxyflavone
Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+
Very-long-chain (3R)-3-hydroxyacyl-CoA <=> Very-long-chain trans-2,3-dehydroacyl-CoA + H2O
Very-long-chain acyl-CoA + NADP+ <=> Very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+
beta-D-Mannosyl-1,4-N-acetyl-D-glucosamine + Orthophosphate <=> N-Acetyl-D-glucosamine + D-Mannose 1-phosphate
Cellobionate + Orthophosphate <=> D-Glucose 1-phosphate + D-Gluconic acid
dTDP-L-vancosamine + Desvancosaminyl-vancomycin <=> dTDP + Vancomycin
UDP-glucose + 7-Deoxyloganetate <=> UDP + 7-Deoxyloganate
UDP-glucose + 7-Deoxyloganetin <=> UDP + Deoxyloganin
AMP + Orthophosphate <=> Adenine + D-Ribose 1,5-bisphosphate
CMP + Orthophosphate <=> Cytosine + D-Ribose 1,5-bisphosphate
UMP + Orthophosphate <=> Uracil + D-Ribose 1,5-bisphosphate
O-Acetyl-L-serine + Isoxazolin-5-one <=> 3-(5-Oxoisoxazolin-2-yl)-L-alanine + Acetate
O-Acetyl-L-serine + Isoxazolin-5-one <=> 3-(5-Oxoisoxazolin-4-yl)-L-alanine + Acetate
D-Galacturonate + NAD+ <=> D-Galactaro-1,5-lactone + NADH + H+
D-Glucuronate + NAD+ <=> D-Glucaro-1,5-lactone + NADH + H+
Zeaxanthin + Oxygen <=> beta-Citraurin + (3S)-3-Hydroxycyclocitral
beta-Citraurin + Oxygen <=> Crocetin dialdehyde + (3S)-3-Hydroxycyclocitral
(2S,3S)-3-Methylphenylalanine + 2-Oxoglutarate <=> (3S)-2-Oxo-3-phenylbutanoate + L-Glutamate
D-Galactaro-1,5-lactone <=> D-Galactaro-1,4-lactone
D-Galactaro-1,4-lactone <=> 5-Dehydro-4-deoxy-D-glucarate
L-Gulonate + NAD+ <=> D-Fructuronate + NADH + H+
Phosphatidylglycerol + alpha-Kojibiosyldiacylglycerol <=> 1,2-Diacyl-sn-glycerol + Glycerophosphoglycoglycerolipid
UDP-glucose + 1,2-Diacyl-sn-glycerol <=> UDP + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol
L-Allothreonine + NADP+ <=> L-2-Amino-3-oxobutanoic acid + NADPH + H+
L-Allothreonine + NADP+ <=> Aminoacetone + CO2 + NADPH + H+
5-Hydroxymethyl-2-furaldehyde + Oxygen <=> Furan-2,5-dicarbaldehyde + Hydrogen peroxide
Furan-2,5-dicarbaldehyde + H2O <=> 5-(Dihydroxymethyl)furan-2-carbaldehyde
5-(Dihydroxymethyl)furan-2-carbaldehyde + Oxygen <=> 5-Formyl-2-furoate + Hydrogen peroxide
5-Formyl-2-furoate + H2O <=> 5-(Dihydroxymethyl)furan-2-carboxylate
5-(Dihydroxymethyl)furan-2-carboxylate + Oxygen <=> 2,5-Furandicarboxylate + Hydrogen peroxide
5-Hydroxymethyl-2-furaldehyde + 3 Oxygen + 2 H2O <=> 2,5-Furandicarboxylate + 3 Hydrogen peroxide
D-Glyceraldehyde 3-phosphate + NAD+ + H2O <=> 3-Phospho-D-glycerate + NADH + H+
3,6-Anhydro-alpha-L-galactopyranose + NAD+ + H2O <=> 3,6-Anhydro-L-galactonate + NADH + H+
3,6-Anhydro-alpha-L-galactopyranose + NADP+ + H2O <=> 3,6-Anhydro-L-galactonate + NADPH + H+
Glycerophosphoglycoglycerolipid <=> Lipoteichoic acid
UDP-alpha-D-galactose + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol <=> UDP + Galactosylglucosyldiacylglycerol
4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 5-Dehydro-4-deoxy-D-glucuronate + N-Acetyl-D-galactosamine 6-sulfate
3'-Phosphoadenylyl sulfate + Dermatan 4-sulfate <=> Adenosine 3',5'-bisphosphate + Dermatan 4,6-sulfate
3'-Phosphoadenylyl sulfate + Chondroitin 4-sulfate <=> Adenosine 3',5'-bisphosphate + Chondroitin 4,6-sulfate
Chondroitin 4-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate
Dermatan 4-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate
Chondroitin 6-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate
3'-Phosphoadenylyl sulfate + Dermatan <=> Adenosine 3',5'-bisphosphate + Dermatan 4-sulfate
dTDP-6-deoxy-D-allose + Mycinamicin VII <=> Mycinamicin VI + dTDP
Mycinamicin VIII + NADPH + Oxygen + H+ <=> Mycinamicin VII + NADP+ + H2O
dTDP-D-desosamine + Protomycinolide IV <=> Mycinamicin VIII + dTDP
Mycinamicin IV + NADPH + Oxygen + H+ <=> Mycinamicin V + NADP+ + H2O
Mycinamicin V + NADPH + Oxygen + H+ <=> Mycinamicin II + NADP+ + H2O
Mycinamicin IV + NADPH + Oxygen + H+ <=> Mycinamicin I + NADP+ + H2O
S-Adenosyl-L-methionine + Nocardicin G <=> 5'-Methylthioadenosine + Isonocardicin C
Isonocardicin C <=> Nocardicin C
N-Acetyl-L-2-amino-6-oxopimelate <=> C20911
C20911 <=> C20912
C20912 <=> C20913
C20913 <=> C20914 + CO2
C20914 + L-Threonine <=> C20915
C20915 <=> C20916
C20916 <=> Tabtoxin
Tabtoxin + H2O <=> Tabtoxinine-beta-lactam + L-Threonine
ATP + Tabtoxinine-beta-lactam + L-Threonine <=> ADP + Orthophosphate + Tabtoxin
Acetyl-CoA + Tabtoxinine-beta-lactam <=> CoA + N1-Acetyl-tabtoxinine-beta-lactam
Tabtoxinine-beta-lactam <=> Tabtoxinine-delta-lactam
Tabtoxin <=> Isotabtoxin
Geranylgeranyl diphosphate <=> Cembrene C + Diphosphate
Geranylgeranyl diphosphate + H2O <=> (R)-Nephthenol + Diphosphate
Geranylgeranyl diphosphate <=> Neocembrene + Diphosphate
Geranylgeranyl diphosphate + H2O <=> (1S,4E,8E,12E)-2,2,5,9,13-Pentamethylcyclopentadeca-4,8,12-trien-1-ol + Diphosphate
3,6-Anhydro-L-galactonate <=> 2-Dehydro-3-deoxy-L-galactonate
ATP + UDP-N-acetylmuramate + L-Alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate
ATP + Tyramine + L-Glutamate <=> ADP + Orthophosphate + gamma-Glutamyltyramine
Nocardicin G <=> Nocardicin E
Succinyl-CoA + Mesaconate <=> Succinate + 2-Methylfumaryl-CoA
Hexadecenoyl-[acyl-carrier protein] + KDO2-lipid IVA <=> (9Z)-Hexadec-9-enoyl-KDO2-lipid IV(A) + Acyl-carrier protein
beta-D-Glucose 6-phosphate + NAD+ <=> D-Glucono-1,5-lactone 6-phosphate + NADH + H+
(S)-Ureidoglycine + Glyoxylate <=> Glycine + Oxalureate
3 ATP <=> pppA2'p5'A2'p5'A + 2 Diphosphate
n ATP <=> 2-5A + (n-1) Diphosphate
Reactive Blue 5 + 2 Hydrogen peroxide <=> Phthalate + 2,2'-Disulfonyl azobenzene + 3-[(4-Amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H2O
(R)-2,3-Dihydroxy-3-methylbutanoate + NAD+ <=> (S)-2-Acetolactate + NADH + H+
L-Dihydroanticapsin + NAD+ <=> L-Anticapsin + NADH + H+
(R)-Ipsdienol + NAD+ <=> Ipsdienone + NADH + H+
(R)-Ipsdienol + NADP+ <=> Ipsdienone + NADPH + H+
Xanthine + 2-Oxoglutarate + Oxygen <=> Urate + Succinate + CO2
Arsenate ion + Thioredoxin <=> Arsenite + Thioredoxin disulfide + H2O
1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 5-phosphate + Orthophosphate
L-Glutamate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-L-glutamate + ADP + Orthophosphate
LysW-L-glutamate + ATP <=> LysW-L-glutamyl 5-phosphate + ADP
LysW-L-glutamyl 5-phosphate + NADPH + H+ <=> LysW-L-glutamate 5-semialdehyde + NADP+ + Orthophosphate
LysW-L-glutamate 5-semialdehyde + L-Glutamate <=> LysW-L-ornithine + 2-Oxoglutarate
LysW-L-ornithine + H2O <=> L-Ornithine + alpha-Aminoadipate carrier protein LysW
Prephenate <=> 3-[(4R)-4-Hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2
(5-Formylfuran-3-yl)methyl phosphate + Orthophosphate + 2 H2O <=> 2 D-Glyceraldehyde 3-phosphate
3-(Methylthio)acryloyl-CoA + 2 H2O <=> Acetaldehyde + Methanethiol + CoA + CO2
alpha-D-Sedoheptulopyranose 7-phosphate <=> 2-epi-5-epi-Valiolone + Orthophosphate
L-Alanyl-D-glutamate <=> L-Alanyl-L-glutamate
(4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione <=> 3-Hydroxy-5-phosphooxypentane-2,4-dione
ATP + Fumarate + L-2,3-Diaminopropanoate <=> AMP + Diphosphate + N3-Fumaroyl-L-2,3-diaminopropanoate
ATP + N(beta)-Epoxysuccinamoyl-DAP + L-Valine <=> ADP + Orthophosphate + N(beta)-Epoxysuccinamoyl-DAP-Val
ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Valine <=> ADP + Orthophosphate + Dapdiamide A
ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Isoleucine <=> ADP + Orthophosphate + Dapdiamide B
ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Leucine <=> ADP + Orthophosphate + Dapdiamide C
3-(Methylthio)acryloyl-CoA + H2O <=> 3-Hydroxy-3-(methylthio)propanoyl-CoA
3-Hydroxy-3-(methylthio)propanoyl-CoA <=> 3-Oxopropionyl-CoA + Methanethiol
3-Oxopropionyl-CoA + H2O <=> 3-Oxopropanoate + CoA
ATP + HCO3- <=> ADP + Carboxyphosphate
Ammonia + Carboxyphosphate <=> Carbamate + Orthophosphate
1D-myo-Inositol 1,3,4-trisphosphate + H2O <=> D-myo-Inositol 1,3-bisphosphate + Orthophosphate
ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate
1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + 1,2-Diacyl-sn-glycerol
ATP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
dTDP-L-rhamnose + 8-Demethyltetracenomycin C <=> dTDP + 8-Demethyl-8-alpha-L-rhamnosyltetracenomycin C
S-Adenosyl-L-methionine + 8-Demethyl-8-alpha-L-rhamnosyltetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C
S-Adenosyl-L-methionine + 8-Demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)tetracenomycin C
S-Adenosyl-L-methionine + 8-Demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin C
S-Adenosyl-L-methionine + 8-Demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + Elloramycin A
10 Malonyl-CoA <=> Tetracenomycin F2 + 10 CoA + 10 CO2 + 2 H2O
S-Adenosyl-L-methionine + 3-Hydroxy-5-methyl-1-naphthoate <=> S-Adenosyl-L-homocysteine + 3-Methoxy-5-methyl-1-naphthoate
S-Adenosyl-L-methionine + 2,7-Dihydroxy-5-methyl-1-naphthoate <=> S-Adenosyl-L-homocysteine + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoate
S-Adenosyl-L-methionine + L-Tyrosine <=> S-Adenosyl-L-homocysteine + 3-Methyl-L-tyrosine
Dimethylallyl diphosphate + 5,10-Dihydrophenazine-1-carboxylate <=> Diphosphate + 9-(Dimethylallyl)-5,10-dihydrophenazine-1-carboxylate
Dimethylallyl diphosphate + L-Tyrosine <=> Diphosphate + 4-O-Dimethylallyl-L-tyrosine
Geranyl diphosphate + Flaviolin <=> 3-Linalylflaviolin + Diphosphate
ATP + 6-Deoxy-6-sulfo-D-fructose <=> ADP + 6-Deoxy-6-sulfo-D-fructose 1-phosphate
3'-Phosphoadenylyl sulfate + alpha,alpha-Trehalose <=> Adenosine 3',5'-bisphosphate + 2-Sulfotrehalose
alpha-D-Ribose 1,2-cyclic phosphate 5-phosphate + H2O <=> D-Ribose 2,5-bisphosphate
D-Ribose 2,5-bisphosphate + H2O <=> D-Ribose 5-phosphate + Orthophosphate
3-Sulfinopropanoyl-CoA + H2O <=> Propanoyl-CoA + Sulfite
[N-(6-Aminohexanoyl)]n(n) + H2O <=> [N-(6-Aminohexanoyl)]n(n-1) + 6-Aminohexanoate
[N-(6-Aminohexanoyl)]n(n) + H2O <=> [N-(6-Aminohexanoyl)]n(n-x) + [N-(6-Aminohexanoyl)]n(x)
6-Aminohexanoate cyclic oligomer + H2O <=> [N-(6-Aminohexanoyl)]n
[N-(6-Aminohexanoyl)]n <=> N-(6-Aminohexanoyl)-6-aminohexanoate
5-Valerolactone + H2O <=> 5-Hydroxypentanoate
5-Hydroxypentanoate + NAD+ <=> 5-Oxopentanoate + NADH + H+
5-Oxopentanoate + NADP+ + H2O <=> Glutarate + NADPH + H+
Juvenile hormone I + H2O <=> Juvenile hormone I acid + Methanol
L-Serine + NADP+ <=> Aminoacetaldehyde + CO2 + NADPH + H+
L-Serine + NAD+ <=> 2-Aminomalonate semialdehyde + NADH + H+
L-Serine + NAD+ <=> Aminoacetaldehyde + CO2 + NADH + H+
Sucrose 6'-phosphate + Orthophosphate <=> D-Glucose 1-phosphate + beta-D-Fructose 6-phosphate
UDP-glucose + beta-D-Glucosyl crocetin <=> UDP + beta-D-Gentiobiosyl crocetin
UDP-glucose + Bis(beta-D-glucosyl) crocetin <=> UDP + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester
UDP-glucose + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester <=> UDP + Crocin
(S)-2-Aminobutanoate + 2-Oxoglutarate <=> 2-Oxobutanoate + L-Glutamate
L-Alanine + 2-Oxobutanoate <=> Pyruvate + (S)-2-Aminobutanoate
ATP + L-Glutamate + (S)-2-Aminobutanoate <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-2-aminobutyrate
ATP + gamma-L-Glutamyl-L-2-aminobutyrate + Glycine <=> ADP + Orthophosphate + Ophthalmate
L-Rhamnose + NAD+ <=> L-Rhamnono-1,4-lactone + NADH + H+
2-Oxobutanoate + Thiamin diphosphate <=> 2-(alpha-Hydroxypropyl)thiamine diphosphate + CO2
2-(alpha-Hydroxypropyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> Enzyme N6-(S-propyldihydrolipoyl)lysine + Thiamin diphosphate
Propanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + Enzyme N6-(S-propyldihydrolipoyl)lysine
Cholesterol + Oxygen + NADH + H+ <=> 7-Dehydrocholesterol + NAD+ + 2 H2O
Cholesterol + Oxygen + NADPH + H+ <=> 7-Dehydrocholesterol + NADP+ + 2 H2O
Hercynine + gamma-L-Glutamyl-L-cysteine + Oxygen <=> gamma-L-Glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O
Hercynine + L-Cysteine + Oxygen <=> S-(Hercyn-2-yl)-L-cysteine S-oxide + H2O
L-Histidine + L-Cysteine + Oxygen <=> S-(L-Histidin-5-yl)-L-cysteine S-oxide + H2O
Iminoarginine + H2O <=> 5-Guanidino-2-oxopentanoate + Ammonia
5,6,7,8-Tetrahydromonapterin + NADP+ <=> 7,8-Dihydromonapterin + NADPH + H+
S-Adenosyl-L-methionine + dTDP-4-oxo-6-deoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-4-oxo-5-C-methyl-L-rhamnose
gamma-L-Glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O <=> S-(Hercyn-2-yl)-L-cysteine S-oxide + L-Glutamate
2-Aminomuconate semialdehyde <=> Picolinic acid + H2O
N-Acetylmuramate + ATP <=> N-Acetylmuramic acid alpha-1-phosphate + ADP
N-Acetylmuramic acid alpha-1-phosphate + UTP <=> UDP-N-acetylmuramate + Diphosphate
(R)-5,6-Dihydrothymine + NAD+ <=> Thymine + NADH + H+
(S)-Methylmalonate semialdehyde <=> (R)-Methylmalonate semialdehyde
2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate <=> 5-Hydroxymethylcytosine in DNA
5-Methylcytosine in DNA + 2-Oxoglutarate + Oxygen <=> 5-Hydroxymethylcytosine in DNA + Succinate + CO2
5-Guanidino-2-oxopentanoate + NADH + H+ + Ammonia <=> L-Arginine + NAD+ + H2O
5-Guanidino-2-oxopentanoate + NADPH + H+ + Ammonia <=> L-Arginine + NADP+ + H2O
L-Arginine <=> N(omega)-Hydroxyarginine
dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose <=> dTDP-3,4-dioxo-2,6-dideoxy-D-glucose
2-Dehydro-3-deoxy-L-galactonate + NAD+ <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate + NADH + H+
Sulfoquinovose + NAD+ <=> 6-Deoxy-6-sulfo-D-glucono-1,5-lactone + NADH + H+
7,8-Dihydroneopterin + Oxygen <=> 7,8-Dihydroxanthopterin + Formate + Glycolaldehyde
(5-Formylfuran-3-yl)methyl phosphate + L-Alanine <=> [5-(Aminomethyl)furan-3-yl]methyl phosphate + Pyruvate
[5-(Aminomethyl)furan-3-yl]methyl phosphate + ATP <=> [5-(Aminomethyl)furan-3-yl]methyl diphosphate + ADP
[5-(Aminomethyl)furan-3-yl]methyl diphosphate + gamma-Glutamyltyramine <=> (4-{4-[2-(gamma-L-Glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + Diphosphate
S-Adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-L-mannose <=> S-Adenosyl-L-homocysteine + dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose
dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose <=> dTDP-L-oleandrose
2 S-Adenosyl-L-methionine + dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose <=> 2 S-Adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose
dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose
dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-megosamine
(S)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide
5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + H2O <=> 6-Hydroxypseudooxynicotine
(R)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + NADPH + H+ <=> dTDP-4-oxo-2,6-dideoxy-D-allose + NADP+
all-trans-8'-Apo-beta-carotenal + Oxygen <=> 13-Apo-beta-carotenone + 2,6-Dimethyldeca-2,4,6,8-tetraenedial
UMP + 2-Oxoglutarate + Oxygen <=> 5'-Dehydrouridine + Succinate + CO2 + Orthophosphate
2-Phytyl-1,4-naphthoquinone + NADPH + H+ <=> Demethylphylloquinol + NADP+
Phosphatidylglycerol + Phosphatidylethanolamine <=> Cardiolipin + Ethanolamine
S-Methyl-L-methionine + L-Homocysteine <=> 2 L-Methionine
L-Anticapsin + L-Alanine + ATP <=> Bacilysin + Orthophosphate + ADP
3-[(4R)-4-Hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate <=> 3-[(1E,4R)-4-Hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate
3-[(1E,4R)-4-Hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate <=> (3E)-3-[(1R,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate
(3E)-3-[(1R,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + NADH + H+ <=> 3-[(1R,2S,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + NAD+
3-[(1R,2S,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-Phenylalanine <=> L-Dihydroanticapsin + Phenylpyruvate
Terpentetriene <=> Terpentecin
trans-Cinnamate <=> Styrene + CO2
Ferulate <=> 4-Vinylguaiacol + CO2
2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one <=> Dihydroneopterin phosphate + H2O
7,8-Dihydroneopterin <=> 7,8-Dihydromonapterin
(S)-Malate <=> (S)-Lactate + CO2
L-Altarate <=> 5-Dehydro-4-deoxy-D-glucarate + H2O
(R)-2-Hydroxyisocaproyl-CoA <=> Isocaprenoyl-CoA + H2O
D-Galactarate <=> (2S,3R)-2,3-Dihydroxy-5-oxohexanedioate + H2O
L-Isoleucine <=> D-allo-Isoleucine
2-epi-5-epi-Valiolone <=> 5-epi-Valiolone
3-D-Glucosyl-1,2-diacylglycerol <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol
2-epi-5-epi-Valiolone 7-phosphate <=> 5-epi-Valiolone 7-phosphate
7,8-Dihydroneopterin 3'-triphosphate <=> 7,8-Dihydromonapterin 3'-triphosphate
D-Glucaro-1,4-lactone <=> 5-Dehydro-4-deoxy-D-glucarate
ATP + L-allo-Isoleucine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-allo-Isoleucyl-[peptidyl-carrier protein]
ATP + L-Arginine + L-Amino acid <=> ADP + Orthophosphate + L-Arginyl-L-amino acid
Geranyl diphosphate + 2-O,3-Dimethylflaviolin <=> Diphosphate + 6-Linalyl-2-O,3-dimethylflaviolin
Geranyl diphosphate + 2-O,3-Dimethylflaviolin <=> Diphosphate + 7-O-Geranyl-2-O,3-dimethylflaviolin
S-Adenosylmethioninamine + Norspermidine <=> 5'-Methylthioadenosine + Norspermine + H+
S-Adenosylmethioninamine + Norspermine <=> 5'-Methylthioadenosine + Caldopentamine + H+
ATP + Protein-L-arginine <=> ADP + Protein N(omega)-phospho-L-arginine
2,6-Dichloro-p-benzoquinone + NADH + H+ <=> 2,6-Dichlorohydroquinone + NAD+
2,5-Dichloro-p-benzoquinone + NADH + H+ <=> 2,5-Dichlorohydroquinone + NAD+
5-Chloro-2-hydroxy-p-benzoquinone + NADH + H+ <=> 5-Chloro-1,2,4-trihydroxybenzene + NAD+
5'-Deoxyadenosine + H2O <=> 5'-Deoxyinosine + Ammonia
Protein N(omega)-phospho-L-arginine + H2O <=> Protein-L-arginine + Orthophosphate
24-Methylenecholesterol + NADPH + H+ <=> 24-epi-Campesterol + NADP+
24-epi-Campesterol + NADPH + H+ + Oxygen <=> Brassicasterol + NADP+ + 2 H2O
2-Iminobutanoate + H2O <=> 2-Oxobutanoate + Ammonia
2-Iminopropanoate + H2O <=> Pyruvate + Ammonia
Dehydroalanine <=> 2-Iminopropanoate
2-Aminobut-2-enoate <=> 2-Iminobutanoate
5-Phospho-alpha-D-ribose 1-diphosphate + 4-Hydroxybenzoate <=> 4-(beta-D-Ribofuranosyl)phenol 5'-phosphate + CO2 + Diphosphate
L-allo-Isoleucyl-[peptidyl-carrier protein] + Peptidyl-carrier protein <=> Peptidyl-carrier protein + L-allo-Isoleucyl-[peptidyl-carrier protein]
NADH + H2O <=> AMP + NMNH
7-Chloro-L-tryptophan + Oxygen <=> Monodechloroaminopyrrolnitrin + CO2 + 2 H2O
Monodechloroaminopyrrolnitrin + FADH2 + Cl- + Oxygen + H+ <=> Aminopyrrolnitrin + FAD + 2 H2O
Adenosylhopane + H2O <=> Ribosylhopane + Adenine
Ribosylhopane <=> Bacteriohopanetetrol
Bacteriohopanetetrol + UDP-N-acetyl-alpha-D-glucosamine <=> Bacteriohopanetetrol-acetylglucosamine + UDP
Bacteriohopanetetrol-acetylglucosamine + H2O <=> Bacteriohopanetetrol-glucosamine + Acetate
Bacteriohopanetetrol-glucosamine <=> Bacteriohopanetetrol cyclitol ether
Ribosylhopane + L-Glutamate <=> Aminobacteriohopanetriol + 2-Oxoglutarate
L-Tryptophan + Oxygen <=> IPA imine + Hydrogen peroxide
2 IPA imine <=> Chromopyrrolate
Chromopyrrolate + 2 Oxygen + 2 NADH + 3 H+ <=> K-252c + 2 CO2 + 3 H2O + 2 NAD+
K-252c + dTDP-L-ristosamine <=> Holyrine A + dTDP
Holyrine A <=> O-Demethyl-N-demethyl-staurosporine
Monacolin J acid + (S)-2-Methylbutanoyl-[acp] <=> Lovastatin acid + Acyl-carrier protein
2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate <=> beta-D-Glucose 1-phosphate + Glycerol
1,2-beta-D-Glucan(n) + (n-2) Orthophosphate <=> Sophorose + (n-2) D-Glucose 1-phosphate
O-Demethyl-N-demethyl-staurosporine <=> 3'-Demethylstaurosporine
2 IPA imine <=> Protodeoxyviolaceinic acid
Protodeoxyviolaceinic acid + Oxygen + NADPH + H+ <=> Deoxyviolaceinic acid + NADP+ + H2O
Deoxyviolaceinic acid + Oxygen <=> Deoxyviolacein + CO2 + H2O
Protodeoxyviolaceinic acid + NADPH + Oxygen + H+ <=> Protoviolaceinic acid + NADP+ + H2O
Protoviolaceinic acid + Oxygen + NADPH + H+ <=> Violaceinic acid + NADP+ + H2O
Violaceinic acid + Oxygen <=> Violacein + CO2 + H2O
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose
dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-ristosamine
1,3-alpha-D-Glucan(n) + (n-2) Orthophosphate <=> Nigerose + (n-2) beta-D-Glucose 1-phosphate
Pyruvate + trans-2-Octenal <=> (S)-3-Acetyloctanal + CO2
ATP + (R)-Lipoate + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + AMP + Diphosphate
Isolithocholate + NAD+ <=> 3-Oxo-5beta-cholanate + NADH + H+
Lithocholic acid + NADP+ <=> 3-Oxo-5beta-cholanate + NADPH + H+
Isolithocholate + NADP+ <=> 3-Oxo-5beta-cholanate + NADPH + H+
3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
Aurachin B + H2O <=> 3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
Aurachin B + NAD+ + H2O <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
4-Methyl-5-nitrocatechol + NADH + Oxygen + H+ <=> 2-Hydroxy-5-methylquinone + NAD+ + Nitrite + H2O
1,3,7-Trimethyluric acid + NADH + H+ + Oxygen <=> 1,3,7-Trimethyl-5-hydroxyisourate + NAD+ + H2O
2 S-Adenosylmethioninamine + Spermidine <=> 2 5'-Methylthioadenosine + N4-Bis(aminopropyl)spermidine
Protoasukamycin + NADH + H+ + Oxygen <=> 4-Hydroxyprotoasukamycin + NAD+ + H2O
Asperlicin C + NADH + H+ + Oxygen <=> Asperlicin E + NAD+ + H2O
Asperlicin C + NADPH + H+ + Oxygen <=> Asperlicin E + NADP+ + H2O
Protodeoxyviolaceinic acid + NADH + H+ + Oxygen <=> Protoviolaceinic acid + NAD+ + H2O
S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + N4-Aminopropylspermidine
S-Adenosylmethioninamine + N4-Aminopropylspermidine <=> 5'-Methylthioadenosine + N4-Bis(aminopropyl)spermidine
Dibenzothiophene + Reduced FMN + Oxygen <=> Dibenzothiophene-5-oxide + FMN + H2O
Dibenzothiophene-5-oxide + Reduced FMN + Oxygen <=> Dibenzothiophene-5,5-dioxide + FMN + H2O
Dibenzothiophene + 2 Reduced FMN + 2 Oxygen <=> Dibenzothiophene-5,5-dioxide + 2 FMN + 2 H2O
Dibenzothiophene-5,5-dioxide + Reduced FMN + Oxygen + NADH <=> 2'-Hydroxybiphenyl-2-sulfinate + FMN + H2O + NAD+ + H+
Peptide diphthine methyl ester + H2O <=> Peptide diphthine + Methanol
Protein N(pi)-phospho-L-histidine + 2-O-(alpha-D-Mannosyl)-D-glycerate <=> Protein histidine + 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate
Protein N(pi)-phospho-L-histidine + Chitobiose <=> Protein histidine + N,N'-Diacetylchitobiose 6'-phosphate
Protein N(pi)-phospho-L-histidine + D-Galactose <=> Protein histidine + D-Galactose 6-phosphate
Protein N(pi)-phospho-L-histidine + Cellobiose <=> Protein histidine + 6-Phospho-beta-D-glucosyl-(1,4)-D-glucose
N-Methylmyosmine + H2O <=> Pseudooxynicotine
Pseudooxynicotine + H2O <=> 3-Succinoylpyridine + Methylamine
Pseudouridine 5'-phosphate + H2O <=> Pseudouridine + Orthophosphate
Isatin + H2O <=> Isatinate
Glycerone phosphate + Acetyl-CoA <=> 3-Hydroxy-5-phosphooxypentane-2,4-dione + CoA
ATP + (S)-4,5-Dihydroxypentane-2,3-dione <=> ADP + (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
ATP + Acarbose <=> ADP + Acarbose 7IV-phosphate
ATP + 2-epi-5-epi-Valiolone <=> ADP + 2-epi-5-epi-Valiolone 7-phosphate
Dihydromonacolin L-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Dihydromonacolin L acid
Nucleoside 3',5'-bisphosphate + H2O <=> Nucleoside 5'-phosphate + Orthophosphate
2,4-Dinitroanisole + H2O <=> Methanol + 2,4-Dinitrophenol
L-Alanyl-gamma-D-glutamyl-L-lysine + H2O <=> L-Alanyl-D-glutamate + L-Lysine
S-Adenosyl-L-methionine + 7-Demethylmitomycin A <=> S-Adenosyl-L-homocysteine + Mitomycin A
S-Adenosyl-L-methionine + 7-Demethylmitomycin B <=> S-Adenosyl-L-homocysteine + Mitomycin B
S-Adenosyl-L-methionine + (4E,8E)-Sphinga-4,8-dienine ceramide <=> S-Adenosyl-L-homocysteine + 9-Methyl-(4E,8E)-sphinga-4,8-dienine ceramide
4-Hydroxy-3-methylbenzaldehyde + NADP+ + H2O <=> 4-Hydroxy-3-methylbenzoate + NADPH + H+
4-Hydroxy-3-methylbenzoate <=> 4-Hydroxyisophthalate
4-Hydroxyisophthalate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NAD+ + CO2
4-Hydroxyisophthalate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NADP+ + CO2
2 Sinapoyl-CoA + Spermidine <=> 2 CoA + N1,N8-Bis(sinapoyl)spermidine
2 p-Coumaroyl-CoA + Spermidine <=> 2 CoA + N1,N8-Bis(4-coumaroyl)spermidine
Palmitoleoyl-CoA + [Wnt]-L-serine <=> CoA + [Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine
[Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine + H2O <=> [Wnt]-L-serine + (9Z)-Hexadecenoic acid
5'-Triphospho-[mRNA] + GDP <=> Diphosphate + G(5')pppPur-mRNA
Phosphatidylethanolamine + KDO2-lipid IVA <=> 1,2-Diacyl-sn-glycerol + PEtN-KDO2-lipid IV(A)
Dihydrocaffeoyl-CoA + Caffeate <=> 3,4-Dihydroxyphenylpropanoate + Caffeoyl-CoA
ATP + Prokaryotic ubiquitin-like protein + Protein lysine <=> ADP + Orthophosphate + Pupylated protein
Pupylated protein + H2O <=> Prokaryotic ubiquitin-like protein + Protein lysine
[Prokaryotic ubiquitin-like protein]-L-glutamine + H2O <=> Prokaryotic ubiquitin-like protein + Ammonia
Dihydroanhydropodorhizol + 2-Oxoglutarate + Oxygen <=> Deoxypodophyllotoxin + Succinate + CO2 + H2O
2-Dehydro-3,6-dideoxy-6-sulfo-D-gluconate <=> (2S)-3-Sulfolactaldehyde + Pyruvate
6-Deoxy-6-sulfo-D-gluconate <=> 2-Dehydro-3,6-dideoxy-6-sulfo-D-gluconate + H2O
6-Tuliposide B <=> Tulipalin B + D-Glucose
S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine
S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine
S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine
2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine
2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine
S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N5-methyl-L-arginine
Palmitoylphosphatidylcholine + Hexa-acyl lipid A in lipopolysaccharide <=> 2-Acyl-sn-glycero-3-phosphocholine + Hepta-acyl lipid A in lipopolysaccharide
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate + Archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate <=> UDP + Archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy-beta-D-glucuronsyl)-N-acetyl-alpha-D-glucosaminyl phosphate
Dimethylallyl phosphate + Reduced FMN <=> Prenylated FMNH2 + Orthophosphate
Epoxypheophorbide a + H2O <=> Red chlorophyll catabolite
GTP + Gentamicin C <=> GDP + Gentamicin C 2''-phosphate
S-Adenosyl-L-methionine + Pluviatolide <=> S-Adenosyl-L-homocysteine + Bursehernin
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NAD+ + 2 H2O <=> L-2-Aminoadipate + NADH + H+
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADP+ + 2 H2O <=> L-2-Aminoadipate + NADPH + H+
5-epi-Valiolone <=> Valienone + H2O
Valienone + ATP <=> Valienone 7-phosphate + ADP
Valienone 7-phosphate <=> 1-epi-Valienol 7-phosphate
Valienone 7-phosphate <=> Validone 7-phosphate
1-epi-Valienol 1-phosphate + Nucleoside triphosphate <=> NDP-1-epi-valienol + Diphosphate
Validone 7-phosphate <=> Validamine 7-phosphate
Validamine 7-phosphate + NDP-1-epi-valienol <=> Validoxylamine A 7'-phosphate + NDP
Validoxylamine A 7'-phosphate + H2O <=> Validoxylamine A + Orthophosphate
Validoxylamine A + UDP-glucose <=> Validamycin A + UDP
6-Deoxy-6-sulfo-D-glucono-1,5-lactone + H2O <=> 6-Deoxy-6-sulfo-D-gluconate
5-epi-Valiolone 7-phosphate + NADH + H+ <=> 5-epi-Valiolol 7-phosphate + NAD+
5-epi-Valiolol 7-phosphate <=> 1-epi-Valienol 7-phosphate
1-epi-Valienol 7-phosphate <=> 1,7-Diphospho-1-epi-valienol
1,7-Diphospho-1-epi-valienol + Nucleoside triphosphate <=> NDP-1-epi-valienol 7-phosphate + Diphosphate
NDP-1-epi-valienol 7-phosphate + dTDP-4-amino-4,6-dideoxy-D-glucose <=> dTDP-acarviose-7-phosphate
dTDP-acarviose-7-phosphate <=> Acarbose 7IV-phosphate
1-epi-Valienol 7-phosphate <=> 1-epi-Valienol 1-phosphate
NDP-1-epi-valienol + 2-Amino-1,5-anhydro-2-deoxyglucitol <=> Salbostatin 6'-phosphate + NDP
Salbostatin 6'-phosphate + H2O <=> Salbostatin + Orthophosphate
2-Amino-5-epi-valiolone <=> 2-Aminovalienone
5-epi-Valiolone <=> 2-Keto-5-epi-valiolone
2-Keto-5-epi-valiolone <=> 2-Amino-5-epi-valiolone
Cetoniacytone B <=> Cetoniacytone A
1-alpha-D-[(1->4)-alpha-D-Glucosyl](n-1)-alpha-D-glucopyranoside + H2O <=> alpha,alpha-Trehalose + Maltodextrin
Maleylpyruvate + H2O <=> Maleic acid + Pyruvate
Protein N(pi)-phospho-L-histidine + H2O <=> Protein histidine + Orthophosphate
Protein N(tau)-phospho-L-histidine + H2O <=> Protein histidine + Orthophosphate
Starch <=> Cyclomaltodextrin
Starch + n H2O <=> (n+1) Maltodextrin
Maltodextrin + H2O <=> Maltose
2-Methylcitrate <=> 2-Methyl-trans-aconitate + H2O
2-Methyl-trans-aconitate <=> (Z)-But-2-ene-1,2,3-tricarboxylate
Ribostamycin + NAD+ <=> 3''-Oxoribostamycin + NADH + H+
3''-Oxoribostamycin + NADPH + H+ <=> Xylostasin + NADP+
Kanamycin X + Oxygen <=> 6'-Oxokanamycin X + Hydrogen peroxide
Kanamycin C + Oxygen <=> 6'-Oxokanamycin C + Hydrogen peroxide
Kanamycin A + 2-Oxoglutarate <=> 6'-Oxokanamycin X + L-Glutamate
Kanamycin B + 2-Oxoglutarate <=> 6'-Oxokanamycin C + L-Glutamate
UDP-glucose + 2'-Deamino-2'-hydroxyneamine <=> UDP + Kanamycin D
UDP-glucose + Neamine <=> UDP + 3''-Deamino-3''-hydroxykanamycin B
Lividamine + Oxygen <=> 6'-Oxolividamine + Hydrogen peroxide
4'-Oxolividamine + NADPH + H+ <=> Lividamine + NADP+
4'-Oxonebramine + NADPH + H+ <=> Nebramine + NADP+
UDP-kanosamine + Nebramine <=> UDP + Tobramycin
Kanamycin B + Carbamoyl phosphate + ATP + H2O <=> Nebramycin factor 4 + AMP + Diphosphate + Orthophosphate
5-Phospho-alpha-D-ribose 1-diphosphate + Paromamine <=> Diphosphate + 5''-Phosphoribosylparomamine
5''-Phosphoribosylparomamine + H2O <=> 5-Ribosylparomamine + Orthophosphate
UDP-N-acetyl-alpha-D-glucosamine + 5-Ribosylparomamine <=> UDP + 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II
2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II + H2O <=> 6'''-Deamino-6'''-hydroxyparomomycin II + Acetate
6'''-Deamino-6'''-hydroxyparomomycin II + Oxygen <=> 6'''-Deamino-6'''-oxoparomomycin II + Hydrogen peroxide
Paromomycin II + 2-Oxoglutarate <=> 6'''-Deamino-6'''-oxoparomomycin II + L-Glutamate
Paromomycin II <=> Paromomycin
Paromomycin II <=> 5'''-epi-Lividomycin B
5'''-epi-Lividomycin B <=> Lividomycin B
UDP-D-xylose + Paromamine <=> UDP + Gentamicin A2
Gentamicin A2 + NAD+ <=> 3''-Oxogentamicin A2 + NADH + H+
3''-Oxogentamicin A2 + L-Glutamate <=> 3''-Amino-3''-deoxygentamicin A2 + 2-Oxoglutarate
S-Adenosyl-L-methionine + 3''-Amino-3''-deoxygentamicin A2 <=> S-Adenosyl-L-homocysteine + Gentamicin A
Gentamicin X2 + FAD <=> 6'-Oxogentamicin X2 + FADH2
Antibiotic G-418 + FAD <=> 6'-Oxo-G418 + FADH2
6'-Oxogentamicin X2 + L-Glutamate <=> Antibiotic JI-20A + 2-Oxoglutarate
6'-Oxo-G418 + L-Glutamate <=> Antibiotic JI-20Ba + 2-Oxoglutarate
6'-Oxo-G418 + L-Glutamate <=> Antibiotic JI-20B + 2-Oxoglutarate
Gentamicin C2 <=> Gentamicin C2a
Antibiotic JI-20B <=> Antibiotic JI-20Ba
Antibiotic JI-20A <=> Gentamicin C1a
Antibiotic JI-20Ba <=> Gentamicin C2a
Antibiotic JI-20B <=> Gentamicin C2
Acarbose 7IV-phosphate <=> Acarbose
UDP-glucose + D-Glucose <=> alpha,alpha-Trehalose + UDP
Cellulose + H2O <=> Cellulose + Cellodextrin
Cellodextrin <=> Cellobiose
Dextran <=> Isomaltose
beta-D-Glucose 1-phosphate <=> D-Glucose 6-phosphate
Levan <=> Levanbiose
4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> Diphosphate + Thiamin monophosphate + CO2
N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-Amino-5-aminomethyl-2-methylpyrimidine + Formate
Thiamine <=> N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
Pentalen-13-al <=> 1-Deoxypentalenate
Thiamin diphosphate + ADP <=> Thiamin triphosphate + AMP
dTTP + H2O <=> dTMP + Diphosphate
2 Ubiquinol + Oxygen + 4 H+ <=> 2 Ubiquinone + 2 H2O + 4 H+
Sedoheptulose 7-phosphate <=> Demethyl-4-deoxygadusol + Orthophosphate + H2O
Sedoheptulose 7-phosphate <=> 2-epi-Valiolone + Orthophosphate
L-Tryptophan <=> 3-Indoleacrylate + Ammonia
Fe-coproporphyrin III + 2 H+ <=> Coproporphyrin III + Fe2+
D-Erythrulose 1-phosphate <=> Erythrulose 1-phosphate
Erythrulose 1-phosphate <=> D-Erythrulose 4-phosphate
D-Erythrulose 4-phosphate <=> D-Erythrose 4-phosphate
2-Hydroxyisobutanoyl-CoA <=> (S)-3-Hydroxybutanoyl-CoA
2 Ubiquinol + Oxygen + n H+ <=> 2 Ubiquinone + 2 H2O + n H+
(2S,3R)-2-Hydroxy-3-(indol-3-yl)butanoate + NAD+ <=> (R)-3-(Indol-3-yl)-2-oxobutyrate + NADH + H+
(R)-2-Hydroxyglutarate + NAD+ <=> 2-Oxoglutarate + NADH + H+
2-Methylpropane-1,2-diol + NAD+ <=> 2-Hydroxy-2-methylpropanal + NADH + H+
2-Dehydro-3-deoxy-L-rhamnonate + NAD+ <=> 2,4-Diketo-3-deoxy-L-fuconate + NADH + H+
Validamycin A + 2-Oxoglutarate + Oxygen <=> Validamycin B + Succinate + CO2
D-Erythritol 1-phosphate + NADP+ <=> D-Erythrulose 1-phosphate + NADPH + H+
D-Threitol + NAD+ <=> D-Erythrulose + NADH + H+
1-Butanol + Ferricytochrome c <=> Butanal + Ferrocytochrome c + H+
DNA 6-methylaminopurine + 2-Oxoglutarate + Oxygen <=> DNA adenine + Formaldehyde + Succinate + CO2
5-Methylphenazine-1-carboxylate + NADH + Oxygen <=> Pyocyanine + NAD+ + CO2 + H2O
Resorcinol + NADH + H+ + Oxygen <=> Benzene-1,2,4-triol + NAD+ + H2O
Resorcinol + FADH2 + Oxygen <=> Benzene-1,2,4-triol + FAD + H2O
2-Hydroxy-2-methylpropanal + NAD+ + H2O <=> 2-Hydroxy-2-methylpropanoate + NADH + H+
Glyoxal + H2O + Oxygen <=> Glyoxylate + Hydrogen peroxide
Methylglyoxal + H2O + Oxygen <=> Pyruvate + Hydrogen peroxide
2,6-Dihydroxybenzoate <=> Resorcinol + CO2
RCH2NHR' + H2O + Oxygen <=> Aldehyde + R'NH2 + Hydrogen peroxide
3-(1-Carboxyvinyloxy)anthranilate <=> 3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate
3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate <=> 3,4-Dihydro-7-hydroxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate
3,4-Dihydro-7-hydroxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate <=> 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid
3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid <=> 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA
L-Tyrosine <=> (S)-beta-Tyrosine
ATP + (S)-beta-Tyrosine + Peptidyl-carrier protein <=> AMP + Diphosphate + (S)-beta-Tyrosyl-[pcp]
(S)-beta-Tyrosyl-[pcp] + FADH2 + Cl- + Oxygen + H+ <=> (S)-3-Chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
(S)-beta-Tyrosyl-[pcp] <=> 3-(4-Hydroxyphenyl)-3-oxopropanoyl-[pcp]
ATP + 6-Methylsalicylate + CoA <=> AMP + Diphosphate + 6-Methylsalicylyl-CoA
S-Adenosyl-L-methionine + 6-Methylsalicylyl-CoA <=> S-Adenosyl-L-homocysteine + 3,6-Dimethylsalicylyl-CoA
(8S)-3',8-Cyclo-7,8-dihydroguanosine 5'-triphosphate + H2O <=> Precursor Z + Diphosphate
Protoviolaceinic acid + Oxygen + NADH + H+ <=> Violaceinic acid + NAD+ + H2O
Protodeoxyviolaceinic acid + Oxygen + NADH + H+ <=> Deoxyviolaceinic acid + NAD+ + H2O
Mandelonitrile + Oxygen <=> Benzoyl cyanide + Hydrogen peroxide
(2E,6E)-Farnesol + Oxygen <=> 2-trans,6-trans-Farnesal + Hydrogen peroxide
Aurachin C + NADH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ + H2O
Aurachin C + NADPH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP+ + H2O
Aurachin C + NADH + H+ + Oxygen <=> Aurachin C epoxide + NAD+ + H2O
Aurachin C + NADPH + H+ + Oxygen <=> Aurachin C epoxide + NADP+ + H2O
Aurachin C epoxide <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
3,6,7,8-Tetrahydroxy-2-naphthoate <=> 3-Hydroxy-6,7,8-trimethoxy-2-naphthoate
3-Hydroxy-6,7,8-trimethoxy-2-naphthoate <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate
3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate + CoA <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
Azatyrosine <=> (R)-2-Aza-beta-tyrosine
ATP + (R)-2-Aza-beta-tyrosine + Peptidyl-carrier protein <=> AMP + Diphosphate + (R)-2-Aza-beta-tyrosyl-[pcp]
(R)-2-Aza-beta-tyrosyl-[pcp] + FADH2 + Cl- + Oxygen + H+ <=> (R)-2-Aza-3-chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
3-Deoxy-D-manno-octulosonate + Oxygen <=> 8-Dehydro-3-deoxy-D-manno-octulosonate + Hydrogen peroxide
8-Amino-3,8-dideoxy-D-manno-octulosonate + 2-Oxoglutarate <=> 8-Dehydro-3-deoxy-D-manno-octulosonate + L-Glutamate
CTP + 8-Amino-3,8-dideoxy-D-manno-octulosonate <=> Diphosphate + CMP-8-amino-3,8-dideoxy-beta-D-manno-octulosonate
1,2-beta-Oligomannan(n) + Orthophosphate <=> 1,2-beta-Oligomannan(n-1) + D-Mannose 1-phosphate
beta-1,2-Mannobiose + Orthophosphate <=> D-Mannose + D-Mannose 1-phosphate
Dolichyl phosphate D-mannose + [Protein]-L-threonine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein]
ATP + 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] <=> ADP + 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-(6-phospho)mannosyl]-L-threonyl-[protein]
Squalene + FAD + H2O <=> Hydroxysqualene + FADH2
GTP + Valienol 1-phosphate <=> Diphosphate + GDP-valienol
2-Methylpropanamine + FADH2 + Oxygen <=> N-(2-Methylpropanyl)hydroxylamine + FAD + H2O
2-Methylpropanamine + Reduced FMN + Oxygen <=> N-(2-Methylpropanyl)hydroxylamine + FMN + H2O
ATP + Validone <=> ADP + Validone 7-phosphate
2-Phosphinomethylmalate <=> 3-Phosphinomethylmalate
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia
Presqualene diphosphate + H2O <=> Hydroxysqualene + Diphosphate
2-(Glutathion-S-yl)-2-methylbut-3-en-1-ol <=> (3R)-3,4-Epoxy-3-methylbut-1-ene + Glutathione
S-Adenosyl-L-methionine + Orsellinate-[acp] <=> S-Adenosyl-L-homocysteine + 2-Methoxyorsellinate-[acp]
2-Methoxyorsellinate-[acp] + Iodide <=> 5-Iodo-2-methoxyorsellinate-[acp]
5-Iodo-2-methoxyorsellinate-[acp] <=> 3-Hydroxy-5-iodo-2-methoxyorsellinate-[acp]
S-Adenosyl-L-methionine + 3-Hydroxy-5-iodo-2-methoxyorsellinate-[acp] <=> S-Adenosyl-L-homocysteine + 5-Iodo-2,3-dimethoxyorsellinate-[acp]
dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Calicheamicinone <=> dTDP + Calicheamicin T0
dTDP-4-deoxy-4-thio-alpha-D-digitoxose + Calicheamicin T0 <=> dTDP + 4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin T0
4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin T0 + 5-Iodo-2,3-dimethoxyorsellinate-[acp] <=> Calicheamicin PsAg + Acyl-carrier protein
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin PsAg <=> dTDP + Calicheamicin alpha1(I)
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin alpha3(I) <=> dTDP + Calicheamicin gamma(1)I
dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin alpha1(I) <=> dTDP + Calicheamicin gamma(1)I
dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin PsAg <=> dTDP + Calicheamicin alpha3(I)
3-Hydroxy-4-methylanthranilyl-[aryl-carrier protein] + NADH + H+ + Oxygen <=> 3,5-Dihydroxy-4-methylanthranilyl-[aryl-carrier protein] + NAD+ + H2O
[F-actin]-L-methionine + NADPH + Oxygen + H+ <=> [F-actin]-L-methionine-(R)-S-oxide + NADP+ + H2O
(2S,3R)-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+
(2S,3S)-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+
D-Mannose 1-phosphate <=> NDP-D-mannose
NDP-D-mannose <=> NDP-4-oxo-6-deoxy-D-mannose
NDP-4-oxo-6-deoxy-D-mannose <=> NDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose
NDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose <=> NDP-2-amino-4-oxo-2,6-dideoxy-D-galactose
NDP-2-amino-4-oxo-2,6-dideoxy-D-galactose <=> NDP-2-amino-2,6-dideoxy-D-galactose
NDP-2-amino-2,6-dideoxy-D-galactose <=> NDP-2-methylamino-2,6-dideoxy-D-galactose
3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] <=> 1,3,5,7,9,11,13-Pentadecaheptaene + CO2 + Acyl-carrier protein
Phosphoenolpyruvate + D-Mannose 6-phosphate + H2O <=> 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate + Orthophosphate
3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate + H2O <=> 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate + Orthophosphate
CTP + 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate <=> Diphosphate + CMP-3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate
(E)-4-Hydroxyphenylacetaldehyde oxime <=> (Z)-4-Hydroxyphenylacetaldehyde oxime
(-)-Jasmonic acid + NADPH + H+ + Oxygen <=> trans-12-Hydroxyjasmonic acid + NADP+ + H2O
tert-Butyl alcohol + NADPH + H+ + Oxygen <=> 2-Methylpropane-1,2-diol + NADP+ + H2O
Butane + NADH + H+ + Oxygen <=> 1-Butanol + NAD+ + H2O
Tetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxytetracycline + NADP+ + H2O
S-Adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose <=> S-Adenosyl-L-homocysteine + dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-D-glucose
S-Adenosyl-L-methionine + dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-D-glucose <=> S-Adenosyl-L-homocysteine + dTDP-D-forosamine
EDTA + Reduced FMN + Oxygen <=> Ethylenediaminetriacetic acid + Glyoxylate + FMN + H2O
Ethylenediaminetriacetic acid + Reduced FMN + Oxygen <=> Ethylenediamine-N,N'-diacetic acid + Glyoxylate + FMN + H2O
EDTA + 2 Reduced FMN + 2 Oxygen <=> Ethylenediamine-N,N'-diacetic acid + 2 Glyoxylate + 2 FMN + 2 H2O
Dimethyl sulfone + Reduced FMN + Oxygen <=> Methanesulfinic acid + Formaldehyde + FMN + H2O
ATP + L-Erythrulose <=> ADP + Erythrulose 1-phosphate
ATP + D-Erythrulose <=> ADP + D-Erythrulose 4-phosphate
Isocaproyl-CoA + (R)-2-Hydroxyisocaproate <=> Isocaproate + (R)-2-Hydroxyisocaproyl-CoA
2-Amino-2-deoxyisochorismate + H2O <=> (5S,6S)-6-Amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate + Pyruvate
dTDP-4-oxo-5-C-methyl-L-rhamnose <=> dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose
dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose <=> dTDP-4-dimethylamino-4,6-dideoxy-5-C-methyl-D-allose
dTDP-4-oxo-alpha-D-xylose <=> dTDP-3-methyl-4-oxo-alpha-D-ribopyranose
dTDP-3-methyl-4-oxo-alpha-D-ribopyranose <=> dTDP-madurosamine
S-Adenosyl-L-methionine + dTDP-L-rhamnose <=> S-Adenosyl-L-homocysteine + dTDP-3-O-methyl-beta-L-rhamnose
dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-deoxy-4-thio-alpha-D-digitoxose
dTDP-glucose + 2 NAD+ + H2O <=> dTDP-D-glucuronate + 2 NADH + 2 H+
dTDP-D-glucuronate + NAD+ <=> dTDP-4-oxo-alpha-D-xylose + CO2 + NADH + H+
dTDP-4-oxo-alpha-D-xylose <=> dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + H2O
dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + NADPH + H+ <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + NADP+
dTDP-4-amino-2,4-dideoxy-beta-L-xylose + 2-Oxoglutarate <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + L-Glutamate
S-Adenosyl-L-methionine + dTDP-4-amino-2,4-dideoxy-beta-L-xylose <=> S-Adenosyl-L-homocysteine + dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose
tert-Amyl alcohol + NADPH + H+ + Oxygen <=> Isoprenyl alcohol + NADP+ + 2 H2O
Tetracycline + FADH2 + Cl- + Oxygen + H+ <=> Chlortetracycline + FAD + 2 H2O
Acetyl-CoA + 2-Aminoethylphosphonate <=> 2-Acetamidoethylphosphonate + CoA
2-Acetamidoethylphosphonate <=> N-Ethylacetamide
Bialaphos <=> L-Phosphinothricin
S-Adenosyl-L-methionine + Bacteriochlorophyllide c + H2O <=> 7-(Hydroxymethyl)bacteriochlorophyllide c + 5'-Deoxyadenosine + L-Methionine
2 Glyphosate + Oxygen <=> 2 1-Aminomethylphosphonic acid + 2 Glyoxylate
(1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + Oxygen <=> (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1,6-dicarboxylate + Hydrogen peroxide
(1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1,6-dicarboxylate + Oxygen <=> (5aS)-5,5a-Dihydrophenazine-1,6-dicarboxylate + Hydrogen peroxide
(1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate + Oxygen <=> (10aS)-10,10a-Dihydrophenazine-1-carboxylate + Hydrogen peroxide
(1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate + Oxygen <=> 5,10-Dihydrophenazine-1-carboxylate + Hydrogen peroxide
2 (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + 2 H2O
Juglone + H2O <=> Naphthalene-1,2,4,8-tetrol
2 Naphthalene-1,2,4,8-tetrol + Oxygen <=> 2 3,5-Dihydroxy-1,4-naphthoquinone + 2 H2O
GDP-valienol + Validamine 7-phosphate <=> Validoxylamine A 7'-phosphate + GDP
Valienone 7-phosphate <=> Valienol 7-phosphate
Valienol 7-phosphate <=> Valienol 1-phosphate
(2R,3S,4S)-Leucoanthocyanidin + NADP+ <=> (2R,3R)-Dihydroflavonol + NADPH + H+
1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + Hydrogen peroxide <=> Veratraldehyde + o-Methoxyphenol + Glycolaldehyde + H2O
2 (3,4-Dimethoxyphenyl)methanol + Hydrogen peroxide <=> 2 (3,4-Dimethoxyphenyl)methanol radical + 2 H2O
1-(4-Hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + Hydrogen peroxide <=> 4-Hydroxy-3-methoxy-benzaldehyde + o-Methoxyphenol + Glycolaldehyde + H2O
1,2-Dihydro-beta-NAD + H+ + Oxygen <=> NAD+ + Hydrogen peroxide
1,6-Dihydro-beta-NAD + H+ + Oxygen <=> NAD+ + Hydrogen peroxide
Bacteriochlorophyllide d <=> 3-Vinyl bacteriochlorophyllide d + H2O
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine
8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine
12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + H2O <=> 8-Ethyl-12-methylbacteriochlorophyllide d
8,12-Diethyl-3-vinylbacteriochlorophyllide d + H2O <=> 8,12-Diethylbacteriochlorophyllide d
12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + H2O <=> 12-Ethyl-8-propylbacteriochlorophyllide d
12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H2O <=> 12-Ethyl-8-isobutylbacteriochlorophyllide d
Geranylgeranyl diphosphate + Bacteriochlorophyllide a <=> Geranylgeranyl bacteriochlorophyllide a + Diphosphate
ATP + Malonyl-[acyl-carrier protein] + L-Glutamine + H2O <=> AMP + Diphosphate + Malonamoyl-[acyl-carrier protein] + L-Glutamate
Bacteriochlorophyllide b + Geranylgeranyl diphosphate <=> Geranylgeranyl bacteriochlorophyllide b + Diphosphate
S-Adenosyl-L-methionine + 4-Amino-anhydrotetracycline <=> S-Adenosyl-L-homocysteine + 4-Methylamino-4-de(dimethylamino)anhydrotetracycline
S-Adenosyl-L-methionine + 4-Methylamino-4-de(dimethylamino)anhydrotetracycline <=> S-Adenosyl-L-homocysteine + Anhydrotetracycline
Fe-coproporphyrin III + 2 Hydrogen peroxide <=> Heme + 2 CO2 + 4 H2O
[Sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine <=> [Sulfur-carrier protein]-Gly-Gly-L-Cys
[Sulfur-carrier protein]-Gly-Gly-L-Cys + H2O <=> L-Cysteine + Sulfur-carrier protein
Oxytetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxyoxytetracycline + NADP+ + H2O
Chlortetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxy-7-chlortetracycline + NADP+ + H2O
1-Acyl-sn-glycerol 3-phosphate + H2O <=> 1-Acylglycerol + Orthophosphate
L-Cysteine + [Protein]-L-cysteine <=> L-Alanine + [Protein]-S-sulfanyl-L-cysteine
[Enzyme]-S-sulfanylcysteine + [Protein]-L-cysteine <=> [Enzyme]-cysteine + [Protein]-S-sulfanyl-L-cysteine
ADP-glucose + D-Glucose 1-phosphate <=> ADP + alpha-Maltose 1-phosphate
2-Aminomuconate + H2O <=> 2-Hydroxymuconate + Ammonia
S-Adenosyl-L-methionine + Phenazine-1-carboxylate + H+ <=> S-Adenosyl-L-homocysteine + 5-Methylphenazine-1-carboxylate
S-Adenosyl-L-methionine + N-Demethylindolmycin <=> S-Adenosyl-L-homocysteine + Indolmycin
ADP + alpha-D-Ribose 1-phosphate <=> AMP + D-Ribose 1,5-bisphosphate
ATP + Erythritol <=> ADP + D-Erythritol 1-phosphate
ATP + 17-(4-Hydroxyphenyl)heptadecanoate <=> Diphosphate + 17-(4-Hydroxyphenyl)heptadecanoyl adenylate
ATP + 19-(4-Hydroxyphenyl)nonadecanoate <=> Diphosphate + 19-(4-Hydroxyphenyl)nonadecanoyl adenylate
Lithocholoyl-CoA + Cholic acid <=> Lithocholic acid + Choloyl-CoA
Poly(ethylene terephthalate)(n) + H2O <=> Poly(ethylene terephthalate)(n-1) + 4-(2-Hydroxyethoxycarbonyl)benzoate
4-(2-Hydroxyethoxycarbonyl)benzoate + H2O <=> Terephthalate + Ethylene glycol
(2-Aminobenzoyl)acetyl-CoA + H2O <=> (2-Aminobenzoyl)acetate + CoA
Sulfoquinovosyldiacylglycerol + H2O <=> 6-Sulfo-alpha-D-quinovose + 1,2-Diacyl-sn-glycerol
beta-1,2-Mannotriose + H2O <=> beta-1,2-Mannobiose + alpha-D-Mannose
S-Adenosyl-L-methionine + (-)-5'-Demethylyatein <=> S-Adenosyl-L-homocysteine + Dihydroanhydropodorhizol
S-Adenosyl-L-methionine + Methanethiol <=> S-Adenosyl-L-homocysteine + Dimethyl sulfide
Feruloyl-CoA + 2-Oxoglutarate + Oxygen <=> 6-Hydroxyferuloyl-CoA + Succinate + CO2
6-Hydroxyferuloyl-CoA <=> Scopoletin + CoA
Geranyl diphosphate + H2O <=> Geranyl phosphate + Orthophosphate
Geranyl phosphate + H2O <=> Geraniol + Orthophosphate
ATP + D-Ribose 5-phosphate <=> Diphosphate + ADP-ribose
ATP + 3-Hydroxy-4-methylanthranilate <=> Diphosphate + (3-Hydroxy-4-methylanthranilyl)adenylate
CDP-glycerol + N-Acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol <=> CMP + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia
L-Glutaminyl-peptide + H2O <=> L-Glutamyl-protein + Ammonia
N5-Phenyl-L-glutamine + H2O <=> L-Glutamate + Aniline
Protein Nomega-(1-hydroxy-2-oxopropyl)-L-arginine + H2O <=> Protein-L-arginine + Lactate
Protein N6-(1-hydroxy-2-oxopropyl)-L-lysine + H2O <=> Protein lysine + Lactate
Protein S-(1-hydroxy-2-oxopropyl)-L-cysteine + H2O <=> [Protein]-L-cysteine + Lactate
7alpha,12alpha-Dihydroxy-3-oxochol-4-en-24-oyl-CoA <=> 12alpha-Hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O
7alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA <=> 3-Oxochola-4,6-dien-24-oyl-CoA + H2O
2 (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate + H2O
(1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate <=> (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + H2O
(1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + Oxygen <=> (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate + Hydrogen peroxide + CO2
(1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate <=> (1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate
(1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate + Oxygen <=> 5,10-Dihydrophenazine + Hydrogen peroxide + CO2
5,10-Dihydrophenazine + Oxygen <=> Phenazine + Hydrogen peroxide
(5aS)-5,5a-Dihydrophenazine-1,6-dicarboxylate <=> 5,10-Dihydrophenazine-1,6-dicarboxylate
5,10-Dihydrophenazine-1,6-dicarboxylate + Oxygen <=> Phenazine-1,6-dicarboxylic acid + Hydrogen peroxide
(10aS)-10,10a-Dihydrophenazine-1-carboxylate <=> 5,10-Dihydrophenazine-1-carboxylate
5,10-Dihydrophenazine-1-carboxylate + Oxygen <=> Phenazine-1-carboxylate + Hydrogen peroxide
Phenazine-1-carboxylate + NADH + Oxygen + H+ <=> 1-Hydroxyphenazine + NAD+ + CO2 + H2O
Molybdoenzyme molybdenum cofactor + GTP <=> Guanylyl molybdenum cofactor + Diphosphate
Molybdoenzyme molybdenum cofactor + CTP <=> Cytidylyl molybdenum cofactor + Diphosphate
Tetrachlorohydroquinone + NAD+ <=> Chloranil + NADH + H+
Anthraniloyl-CoA + L-Cysteinyl-protein <=> S-Anthraniloyl-L-cysteinyl-protein + CoA
S-Anthraniloyl-L-cysteinyl-protein + Malonyl-CoA <=> (2-Aminobenzoyl)acetyl-CoA + CO2 + S-Anthraniloyl-L-cysteinyl-protein
Anthraniloyl-CoA + Malonyl-CoA <=> (2-Aminobenzoyl)acetyl-CoA + CoA + CO2
S-Octanoyl-L-cysteinyl-protein + (2-Aminobenzoyl)acetate <=> 1-(2-Aminophenyl)decane-1,3-dione + CO2 + L-Cysteinyl-protein
1-(2-Aminophenyl)decane-1,3-dione <=> 2-Heptyl-4(1H)-quinolone + H2O
Ribonucleoside triphosphate + Formate <=> Deoxynucleoside triphosphate + CO2 + H2O
Pyruvate + (R)-2-Hydroxyglutarate <=> (R)-Lactate + 2-Oxoglutarate
L-Proline + 2-Oxoglutarate + Oxygen <=> cis-4-Hydroxy-L-proline + Succinate + CO2
S-Adenosyl-L-methionine + (S)-Reticuline <=> S-Adenosyl-L-homocysteine + (S)-Tembetarine
UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + alpha-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
GDP-L-fucose + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> GDP + alpha-L-Fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R
Geranyl diphosphate + Umbelliferone <=> Diphosphate + 8-Geranylumbelliferone
Geranyl diphosphate + Esculetin <=> Diphosphate + 8-Geranylesculetin
L-Arginine + H2O + Oxygen <=> 5-Guanidino-2-oxopentanoate + Ammonia + Hydrogen peroxide
3-Aminobutanoyl-CoA + 2-Oxoglutarate <=> Acetoacetyl-CoA + L-Glutamate
ATP + 4-Hydroxybenzoate <=> Diphosphate + 4-Hydroxybenzoyl-adenylate
Dimethylallyl diphosphate + 2-Acylphloroglucinol <=> Diphosphate + 2-Acyl-4-prenylphloroglucinol
Dimethylallyl diphosphate + 2-Acyl-4-prenylphloroglucinol <=> Diphosphate + 2-Acyl-4,6-bisprenylphloroglucinol
Dimethylallyl diphosphate + 2-Acyl-4,6-bisprenylphloroglucinol <=> Diphosphate + 2-Acyl-4,6,6-trisprenylcyclohexa-2,4-dien-1-one
CDP-glycerol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> CMP + 4-O-Di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Oxamate + H2O <=> Oxalate + Ammonia
Alditol + Oxygen <=> Aldose + Hydrogen peroxide
3',5'-Cyclic AMP + H2O <=> 3',5'-Cyclic IMP + Ammonia
D-Sorbitol + Oxygen <=> alpha-D-Glucose + Hydrogen peroxide
Jasmonoyl-L-amino acid + H2O <=> (-)-Jasmonic acid + L-Amino acid
D-Tagatose 6-phosphate <=> D-Fructose 6-phosphate
D-Tagaturonate <=> D-Fructuronate
cis-3-Hydroxy-L-proline <=> 1-Pyrroline-2-carboxylate + H2O
Sirohydrochlorin + Nickel(2+) <=> Nickel-sirohydrochlorin + 2 H+
15,17(3)-Seco-F430-17(3)-acid + ATP <=> Coenzyme F430 + ADP + Orthophosphate
(-)-Betonicine <=> Turicine
Stachydrine <=> D-Proline betaine
ATP + L-Carnitine + CoA <=> AMP + Diphosphate + L-Carnitinyl-CoA
GTP + Formate <=> dGTP + CO2 + H2O
ATP + Formate <=> dATP + CO2 + H2O
UTP + Formate <=> dUTP + CO2 + H2O
CTP + Formate <=> dCTP + CO2 + H2O
Galactitol + NAD+ <=> L-Tagatose + NADH + H+
D-Altritol + NAD+ <=> D-Tagatose + NADH + H+
(Z)-2-Methylbutanal oxime <=> 2-Methylbutanenitrile + H2O
(Z)-2-Methylpropanal oxime <=> Isobutyronitrile + H2O
L-N,N-Dihydroxypolyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime + CO2 + H2O
1-aci-Nitro-omega-(methylthio)alkane + Glutathione <=> (E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O
Phenol + FADH2 + Oxygen <=> Catechol + FAD + H2O
N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate + NAD+ + H2O <=> 2-Oxoglutarate + L-2,3-Diaminopropanoate + NADH + H+
2-(Glutathione-S-yl)-hydroquinone + Glutathione <=> Glutathione disulfide + Hydroquinone
2-Methyl-3-n-amyl-dihydropyrrole + FAD <=> 2-Methyl-3-n-amyl-pyrrole + FADH2
4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Methyl-3-n-amyl-pyrrole + ATP <=> Prodigiosin + ADP + Orthophosphate
4-Keto-2-undecylpyrroline + NADPH + H+ <=> 2-Undecylpyrrole + NADP+ + H2O
Dodecanoic acid + Malonyl-CoA + Glycine <=> 4-Keto-2-undecylpyrroline + 2 H2O + 2 CO2 + CoA
Pyrrole-2-carbonyl-[pcp] + Acyl-carrier protein <=> Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Peptidyl-carrier protein
4-Keto-2-undecylpyrroline + NADH + H+ <=> 2-Undecylpyrrole + NAD+ + H2O
Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Malonyl-CoA + L-Serine <=> 4-Hydroxy-2,2'-bipyrrole-5-methanol + CoA + Acyl-carrier protein + 2 CO2 + H2O
4-Hydroxy-2,2'-bipyrrole-5-methanol + NADP+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADPH + H+
4-Hydroxy-2,2'-bipyrrole-5-methanol + NAD+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADH + H+
4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + S-Adenosyl-L-methionine <=> 4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + S-Adenosyl-L-homocysteine
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]
(S)-3-Acetyloctanal + Amino acid <=> 2-Methyl-3-n-amyl-dihydropyrrole + 2-Oxo acid
4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Undecylpyrrole + ATP <=> Undecylprodigiosin + ADP + Orthophosphate
(2S)-3-Sulfolactaldehyde + NAD+ + H2O <=> (S)-3-Sulfolactate + NADH + H+
(2S)-3-Sulfolactaldehyde + NADP+ + H2O <=> (S)-3-Sulfolactate + NADPH + H+
L-2-Aminoadipate 6-semialdehyde + NADP+ + AMP + Diphosphate <=> L-2-Aminoadipate + NADPH + H+ + ATP
1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate
Deacetylisoipecoside + S-Adenosyl-L-methionine <=> 6-O-Methyldeacetylisoipecoside + S-Adenosyl-L-homocysteine
6-O-Methyldeacetylisoipecoside + H2O <=> D-Glucose + 6-O-Methyl-N-deacetylisoipecoside aglycon
6-O-Methyl-N-deacetylisoipecoside aglycon <=> Protoemetine
Protoemetine + Dopamine <=> 7'-O-Dmethylcephaeline + H2O
7'-O-Dmethylcephaeline + S-Adenosyl-L-methionine <=> Cephaeline + S-Adenosyl-L-homocysteine
Cephaeline + S-Adenosyl-L-methionine <=> Emetine + S-Adenosyl-L-homocysteine
(13S,14R)-1,13-Dihydroxy-N-methylcanadine + Acetyl-CoA <=> (13S,14R)-1-Hydroxy-13-O-acetyl-N-methylcanadine + CoA
(13S,14R)-1,8-Dihydroxy-13-O-acetyl-N-methylcanadine <=> 4'-O-Desmethyl-3-O-acetylpapaveroxine + H+
4'-O-Desmethyl-3-O-acetylpapaveroxine + S-Adenosyl-L-methionine <=> 3-O-Acetylpapaveroxine + S-Adenosyl-L-homocysteine
3-O-Acetylpapaveroxine + H2O <=> Papaveroxine + Acetate
4'-O-Desmethyl-3-O-acetylpapaveroxine + H2O <=> 4'-O-Desmethylpapaveroxine + Acetate
4'-O-Desmethylpapaveroxine <=> Narcotoline hemiacetal
Narcotoline hemiacetal + NAD+ <=> Narcotoline + NADH + H+
2 S-Adenosyl-L-methionine + 3-(Aminomethyl)indole <=> 2 S-Adenosyl-L-homocysteine + Gramine
S-Adenosyl-L-methionine + 3-(Aminomethyl)indole <=> S-Adenosyl-L-homocysteine + (1H-Indol-3-yl)-N-methylmethanamine
S-Adenosyl-L-methionine + (1H-Indol-3-yl)-N-methylmethanamine <=> S-Adenosyl-L-homocysteine + Gramine
Acetyl-CoA + (3S)-3,6-Diaminohexanoate <=> CoA + (3S)-6-Acetamido-3-aminohexanoate
GDP-mannose + 1-Phosphatidyl-D-myo-inositol <=> GDP + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol
GDP-mannose + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol <=> GDP + 2,6-Di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
GDP-mannose + 2-O-(6-O-Acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol <=> GDP + 2-O-(6-O-Acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
O-Phospho-L-serine + L-Glutamate <=> N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate + Orthophosphate
ATP + 3-Dehydro-L-erythronate <=> ADP + 3-Dehydro-4-phospho-L-erythronate
ATP + 3-Dehydro-L-threonate <=> ADP + 3-Dehydro-4-phospho-D-erythronate
Acetyl-CoA + H2O + 3-Phosphonopyruvate <=> (R)-2-(Phosphonomethyl)malate + CoA
7-(Dihydroxymethyl)bacteriochlorophyllide c <=> Bacteriochlorophyllide e + H2O
2 S-Adenosyl-L-methionine + Bacteriochlorophyllide c + H2O <=> Bacteriochlorophyllide e + 2 5'-Deoxyadenosine + 2 L-Methionine
UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminide <=> UDP + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-R
CMP-N-acetylneuraminate + beta-D-Galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R <=> CMP + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
3-Dehydro-4-phospho-L-erythronate <=> Glycerone phosphate + CO2
3-Dehydro-4-phospho-D-erythronate <=> Glycerone phosphate + CO2
Dihydroneopterin phosphate <=> 6-(Hydroxymethyl)-7,8-dihydropterin + Glycolaldehyde phosphate
7,8-Dihydroneopterin 3'-triphosphate <=> 6-(Hydroxymethyl)-7,8-dihydropterin + Glycolaldehyde triphosphate
Fructoselysine <=> Psicoselysine
2-Dehydro-L-erythronate <=> 3-Dehydro-L-erythronate
2-Dehydro-D-erythronate <=> 3-Dehydro-L-threonate
ATP + L-Isoleucine + Acetoacetyl-CoA <=> AMP + Diphosphate + Tenuazonic acid + CoA
4-Phospho-D-threonate + NAD+ <=> Glycerone phosphate + NADH + CO2 + H+
4-Phospho-D-erythronate + NAD+ <=> Glycerone phosphate + CO2 + NADH + H+
Indole-3-acetate + NADH + H+ + Oxygen <=> (2-Hydroxy-1H-indol-3-yl)acetate + NAD+ + H2O
(S)-Norreticuline + S-Adenosyl-L-methionine <=> (S)-Norlaudanine + S-Adenosyl-L-homocysteine
Indole-3-acetaldoxime N-oxide + Glutathione <=> S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + H2O
1-aci-Nitro-2-phenylethane + Glutathione <=> S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + H2O
(S)-Norlaudanine + S-Adenosyl-L-methionine <=> (S)-Tetrahydropapaverine + S-Adenosyl-L-homocysteine
Hydroxylaminobenzene + 2 NADP+ + H2O <=> Nitrobenzene + 2 NADPH + 2 H+
(S)-Tetrahydropapaverine + 2 Oxygen <=> Papaverine + 2 Hydrogen peroxide
trans-Aconitate <=> Itaconate + CO2
Itaconate <=> 2-Hydroxyparaconate
Norcraugsodine + NADPH + H+ <=> Norbelladine + NADP+
Noroxopluviine <=> Caranine
Caranine <=> Lycorine
(4aR,10bS)-Noroxomaritidine <=> (4aR,10bS)-Normaritidine
(4aR,10bS)-Noroxomaritidine <=> Elwesine
(4aS,10bR)-Noroxomaritidine <=> Maritinamine
(4aS,10bR)-Noroxomaritidine <=> (-)-8-Demethylmaritidine
(-)-8-Demethylmaritidine <=> Vittatine
Vittatine <=> Haemanthamine
6-Lactoyl-5,6,7,8-tetrahydropterin <=> 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin
6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+
Tetrahydrobiopterin + NADP+ <=> 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADPH + H+
Tetrahydrobiopterin + NADP+ <=> 7,8-Dihydrobiopterin + NADPH + H+
6-Lactoyl-5,6,7,8-tetrahydropterin <=> Sepiapterin
Dihydrobiopterin <=> 7,8-Dihydrobiopterin
2,5-Dioxopentanoate + NAD+ + H2O <=> 2-Oxoglutarate + NADH + H+
3,4-Didehydroadipyl-CoA <=> 5-Carboxy-2-pentenoyl-CoA
2,4,6/3,5-Pentahydroxycyclohexanone + NAD+ <=> 3-Dehydro-scyllo-inosose + NADH + H+
3-Dehydro-scyllo-inosose + H2O <=> 5-Dehydro-L-gluconate
5-Dehydro-L-gluconate <=> D-Tagaturonate
Propanoyl-CoA + Succinate <=> Succinyl-CoA + Propanoate
(2R,3S)-2-Alkyl-3-hydroxyalkanoate + NADP+ <=> (R)-2-Alkyl-3-oxoalkanoate + NADPH + H+
(2R,3S)-2-Alkyl-3-hydroxyalkanoate + ATP <=> cis-3-Alkyl-4-alkyloxetan-2-one + AMP + Diphosphate
(3R,4R)-3-[(1S)-1-Hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP+ <=> (3R,4R)-3-Alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH + H+
2 S-Adenosyl-L-methionine + 8-Amino-8-demethylriboflavin <=> 2 S-Adenosyl-L-homocysteine + Roseoflavin
S-Adenosyl-L-methionine + 8-Amino-8-demethylriboflavin <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(methylamino)riboflavin
S-Adenosyl-L-methionine + 8-Demethyl-8-(methylamino)riboflavin <=> S-Adenosyl-L-homocysteine + Roseoflavin
Acyl-CoA + 2,6-Di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol <=> CoA + 2-O-(6-O-Acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
Acyl-CoA + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol <=> CoA + 2-O-(6-O-Acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol
ADP-glucose + D-Glucose 6-phosphate <=> ADP + alpha,alpha'-Trehalose 6-phosphate
ATP + D-Threonate <=> ADP + 4-Phospho-D-threonate
N-Acetylmuramic acid 6-phosphate + H2O <=> N-Acetylmuramate + Orthophosphate
RNA terminal-2',3'-cyclic-phosphate + H2O <=> RNA 2'-terminal-phosphate
(+)-Kolavenyl diphosphate + H2O <=> (+)-Kolavelool + Diphosphate
Cyclobis-1,6-alpha-nigerosyl + 2 H2O <=> 2 Isomaltose
Cyclobis-1,6-alpha-nigerosyl + H2O <=> alpha-Isomaltosyl-1,3-isomaltose
alpha-Isomaltosyl-1,3-isomaltose + H2O <=> 2 Isomaltose
Isomaltose + H2O <=> beta-D-Glucose + D-Glucose
(E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O <=> (E)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-omega-(methylsulfanyl)alkane-1-imine + L-Glutamate
S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + H2O <=> (E)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethane-1-imine + L-Glutamate
(Glutathione-S-yl)(1H-indol-3-yl)acetonitrile + H2O <=> (L-Cysteinylglycine-S-yl)(1H-indol-3-yl)acetonitrile + L-Glutamate
S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + H2O <=> (Z)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-2-phenylethane-1-imine + L-Glutamate
3'-Phosphoadenylyl sulfate + 12-Hydroxyjasmonate <=> Adenosine 3',5'-bisphosphate + 12-Sulfooxyjasmonate
3 S-Adenosyl-L-methionine + Ornithine lipid <=> 3 S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid
S-Adenosyl-L-methionine + Ornithine lipid <=> S-Adenosyl-L-homocysteine + N-Methylornithine lipid
S-Adenosyl-L-methionine + N-Methylornithine lipid <=> S-Adenosyl-L-homocysteine + N,N-Dimethylornithine lipid
S-Adenosyl-L-methionine + N,N-Dimethylornithine lipid <=> S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] <=> Lyso-ornithine lipid + Acyl-carrier protein
ATP + D-Erythronate <=> ADP + 4-Phospho-D-erythronate
omega-(Methylthio)alkyl-glucosinolate + NADPH + H+ + Oxygen <=> omega-(Methylsulfinyl)alkyl-glucosinolate + NADP+ + H2O
Dimethylamine + NADPH + H+ + Oxygen <=> Methylamine + Formaldehyde + NADP+ + H2O
Hydroxyproline <=> (S)-1-Pyrroline-5-carboxylate + H2O
ent-8alpha-Hydroxylabd-13-en-15-yl diphosphate <=> Geranylgeranyl diphosphate + H2O
Peregrinol diphosphate <=> Geranylgeranyl diphosphate + H2O
trans,trans-Farnesyl diphosphate + H2O <=> (+)-Isoafricanol + Diphosphate
Geranylgeranyl diphosphate <=> (-)-Spiroviolene + Diphosphate
Geranylgeranyl diphosphate <=> Tsukubadiene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (2S,3R,6S,9S)-(-)-Protoillud-7-ene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (3S)-(+)-Asterisca-2(9),6-diene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-alpha-Amorphene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-Corvol ether B + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Eremophilene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (1R,4R,5S)-(-)-Guaia-6,10(14)-diene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-(1E,4E,6S,7R)-Germacra-1(10),4-dien-6-ol + Diphosphate
Geranylgeranyl diphosphate + H2O <=> (3E,7E)-Dolabella-3,7-dien-18-ol + Diphosphate
Geranylgeranyl diphosphate <=> (3E,7E)-Dolathalia-3,7,11-triene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 7-epi-alpha-Eudesmol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 4-epi-Cubebol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-Corvol ether A + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-Juneol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> tau-Cadinol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (2E,6E)-Hedycaryol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-Cubebol + Diphosphate
all-trans-Pentaprenyl diphosphate + H2O <=> Sesterfisherol + Diphosphate
Geranyl diphosphate <=> beta-Thujene + Diphosphate
all-trans-Pentaprenyl diphosphate <=> Stellata-2,6,19-triene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Guaia-4,6-diene + Diphosphate
Geranylgeranyl diphosphate <=> Pseudolaratriene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Selina-4(15),7(11)-diene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-(2S,3R,9R)-Pristinol + Diphosphate
Copalyl diphosphate + H2O <=> Nezukol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 5-Hydroxy-alpha-gurjunene + Diphosphate
ent-Copalyl diphosphate <=> ent-Atiserene + Diphosphate
ent-8alpha-Hydroxylabd-13-en-15-yl diphosphate <=> ent-13-epi-Manoyl oxide + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (2Z,6E)-Hedycaryol + Diphosphate
all-trans-Pentaprenyl diphosphate <=> beta-Geranylfarnesene + Diphosphate
all-trans-Hexaprenyl diphosphate <=> beta-Hexaprene + Diphosphate
all-trans-Heptaprenyl diphosphate <=> beta-Heptaprene + Diphosphate
Peregrinol diphosphate <=> (13R)-9,13-Epoxylabd-14-ene + Diphosphate
Copal-8-ol diphosphate <=> Manoyl oxide + Diphosphate
Geranylgeranyl diphosphate <=> Cycloaraneosene + Diphosphate
(13E)-Labda-7,13-dien-15-yl diphosphate <=> Labda-7,13(16),14-triene + Diphosphate
Copalyl diphosphate <=> (12E)-Labda-8(17),12,14-triene + Diphosphate
Glutathione <=> Cys-Gly + 5-Oxoproline
epsilon-(gamma-L-Glutamyl)-L-lysine <=> L-Lysine + 5-Oxoproline
S-(Hercyn-2-yl)-L-cysteine S-oxide + H2O <=> 2-(Hydroxysulfanyl)hercynine + Pyruvate + Ammonia
Linalool <=> Geraniol
(3S,22S)-2,3:22,23-Diepoxy-2,3,22,23-tetrahydrosqualene <=> Pre-alpha-onocerin
Pre-alpha-onocerin <=> alpha-Onocerin
Geranylgeranyl diphosphate <=> (-)-Kolavenyl diphosphate
Geranylgeranyl diphosphate <=> (+)-Kolavenyl diphosphate
Geranylgeranyl diphosphate <=> (13E)-Labda-7,13-dien-15-yl diphosphate
ATP + 4-Hydroxybenzoate + Acyl-carrier protein <=> AMP + Diphosphate + 4-Hydroxybenzoyl-[acp]
4-Hydroxybenzoyl-adenylate + Acyl-carrier protein <=> AMP + 4-Hydroxybenzoyl-[acp]
Reduced coenzyme F420 + Methanophenazine <=> Coenzyme F420 + Dihydromethanophenazine
L-Carnitine + NADH + H+ + Oxygen <=> (3R)-3-Hydroxy-4-oxobutanoate + Trimethylamine + NAD+ + H2O
2 4-Sulfanylbutanoate + NAD+ <=> 4,4'-Disulfanediyldibutanoate + NADH + H+
(4R)-4,2'-Dihydroxyisoflavan + NADP+ <=> (3R)-2'-Hydroxyisoflavanone + NADPH + H+
[Sulfatase]-L-cysteine + Oxygen + 2 Thiol <=> [Sulfatase]-3-oxo-L-alanine + Hydrogen sulfide + Oxidized thiol-containing reductant + H2O
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-R <=> UDP + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-R
3'-Phosphoadenylyl sulfate + 7-Methylthioheptyl-desulfoglucosinolate <=> Adenosine 3',5'-bisphosphate + 7-Methylthioheptyl glucosinolate
3'-Phosphoadenylyl sulfate + 8-Methylthiooctyl-desulfoglucosinolate <=> Adenosine 3',5'-bisphosphate + 8-Methylthiooctyl glucosinolate
Chitobiose + H2O <=> N-Acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + Acetate
Carmofur <=> 5-FU
ATP + 5-Fluorouridine monophosphate <=> ADP + 5-Fluorouridine diphosphate
ATP + 5-Fluorodeoxyuridine monophosphate <=> ADP + 5-Fluorodeoxyuridine diphosphate
5-Fluorodeoxyuridine diphosphate + Thioredoxin disulfide + H2O <=> 5-Fluorouridine diphosphate + Thioredoxin
ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate
ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate
5-Fluorodeoxyuridine triphosphate + H2O <=> 5-Fluorodeoxyuridine monophosphate + Diphosphate
Ethylene oxide + Coenzyme M <=> 2-Hydroxyethyl-CoM
2-Hydroxyethyl-CoM <=> Acetyl-CoA
Chloroethylene oxide + Coenzyme M <=> 2-Chloro-2-hydroxyethyl-CoM
2-Chloro-2-hydroxyethyl-CoM <=> Acetyl-CoA
Vinyl chloride + NADH + H+ + Oxygen <=> Chloroethylene oxide + NAD+ + H2O
Acetyl-CoA + Hydrazine <=> CoA + Acetylhydrazine
Acetylhydrazine + H2O <=> Hydrazine + Acetate
Isoniazid + Hydrogen peroxide <=> Isonicotinoyl radical + Diimine + 2 H2O
Isonicotinoyl radical + NAD+ <=> Isonicotinoyl-NAD adduct
Isonicotinoyl radical + NADP+ <=> Isonicotinoyl-NADP adduct
L-Carnitine + NADPH + H+ + Oxygen <=> (3R)-3-Hydroxy-4-oxobutanoate + Trimethylamine + NADP+ + H2O
3,4-Dihydroxy-L-phenylalanine + Oxygen + H2O <=> 3,4-Dihydroxyphenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide
L-Tyrosine + Oxygen + H2O <=> 4-Hydroxyphenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide
L-Phenylalanine + Oxygen + H2O <=> Phenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide
Geranylgeranyl diphosphate <=> Rhizathalene A + Diphosphate
Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide <=> Pyridinium-3,5-bisthiocarboxylate mononucleotide + Nickel(2+)
ATP + 17-(4-Hydroxyphenyl)heptadecanoate + Acyl-carrier protein <=> AMP + Diphosphate + 17-(4-Hydroxyphenyl)heptadecanoyl-[acp]
17-(4-Hydroxyphenyl)heptadecanoyl adenylate + Acyl-carrier protein <=> AMP + 17-(4-Hydroxyphenyl)heptadecanoyl-[acp]
ATP + 19-(4-Hydroxyphenyl)nonadecanoate + Acyl-carrier protein <=> AMP + Diphosphate + 19-(4-Hydroxyphenyl)nonadecanoyl-[acp]
19-(4-Hydroxyphenyl)nonadecanoyl adenylate + Acyl-carrier protein <=> AMP + 19-(4-Hydroxyphenyl)nonadecanoyl-[acp]
ATP + L-Firefly luciferin + CoA <=> AMP + Diphosphate + L-Firefly luciferyl-CoA
[(3S,4R)-4-Alkanoyl-5-oxooxolan-3-yl]methyl phosphate + NADP+ <=> (4-Alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate + NADPH + H+
1-(4-Methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O <=> 2-({[(4-Methoxyphenyl)methyl](methyl)amino}methyl)-2-methylpropane-1,3-diol
4-Hydroxy-L-tryptophan <=> 4-Hydroxytryptamine + CO2
ATP + 4-Hydroxytryptamine <=> ADP + Norbaeocystin
2 S-Adenosyl-L-methionine + Norbaeocystin <=> 2 S-Adenosyl-L-homocysteine + Psilocybin
S-Adenosyl-L-methionine + Norbaeocystin <=> S-Adenosyl-L-homocysteine + Baeocystin
S-Adenosyl-L-methionine + Baeocystin <=> S-Adenosyl-L-homocysteine + Psilocybin
GDP-mannose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> GDP + alpha-D-Mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP-glucose + Mogrol <=> Mogroside IE + UDP
Dimethylallyl diphosphate + 3 Isopentenyl diphosphate <=> 3 Diphosphate + Nerylneryl diphosphate
ATP + L-Glutamine + H2O <=> AMP + Orthophosphate + N5-Phospho-L-glutamine
Oleuropein + H2O <=> Oleuropein aglycone + D-Glucose
Ubiquinone + NADH + 6 H+ <=> Ubiquinol + NAD+ + 5 H+
S-Sulfanylglutathione + Oxygen <=> S-Sulfinatoglutathione
S-Sulfinatoglutathione + H2O <=> Glutathione + Sulfite
Ornithine lipid + 2-Oxoglutarate + Oxygen <=> 2-Hydroxyornithine lipid + Succinate + CO2
ATP + (-)-Jasmonic acid + L-Amino acid <=> AMP + Diphosphate + Jasmonoyl-L-amino acid
S-Adenosyl-L-methionine + Adenine in U6 snRNA <=> S-Adenosyl-L-homocysteine + N6-Methyladenine in U6 snRNA
S-Adenosyl-L-methionine + (+)-Kolavelool <=> S-Adenosyl-L-homocysteine + (+)-O-Methylkolavelool
Sesamin + Tetrahydrofolate <=> (+)-Demethylpiperitol + 5,10-Methylenetetrahydrofolate
(+)-Demethylpiperitol + Tetrahydrofolate <=> (+)-Didemethylpinoresinol + 5,10-Methylenetetrahydrofolate
Acetyl-CoA + Ethanol <=> CoA + Ethyl acetate
2 Acyl-CoA + H2O <=> (R)-2-Alkyl-3-oxoalkanoate + 2 CoA
2-O-(alpha-D-Glucopyranosyl)-D-glycerate + Orthophosphate <=> D-Glucose 1-phosphate + D-Glycerate
FMN + Oxygen <=> 8-Demethyl-8-formylriboflavin 5'-phosphate + H2O
ATP + Rifampicin + H2O <=> AMP + 21-Phosphorifampicin + Orthophosphate
UDP-L-rhamnose + alpha-D-Galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl]n <=> UDP + [(1->2)-alpha-L-Rhamnosyl-(1->4)-alpha-D-galacturonosyl]n
(2R,3S,4S)-Leucoanthocyanidin + 2-Oxoglutarate + Oxygen <=> (4S)- 2,3-Dehydroflavan-3,4-diol + Succinate + CO2 + H2O
(4S)- 2,3-Dehydroflavan-3,4-diol + H+ <=> Anthocyanidin with a 3-hydroxy group + H2O
(2R,3S,4S)-Leucoanthocyanidin + 2-Oxoglutarate + Oxygen + H+ <=> Anthocyanidin with a 3-hydroxy group + Succinate + CO2 + 2 H2O
(S)-Lactate + Oxygen <=> Pyruvate + Hydrogen peroxide
cis-1,4-Polyisoprene + n Oxygen <=> n (4Z,8Z)-4,8-Dimethyl-12-oxotrideca-4,8-dienal
Siroheme <=> 12,18-Didecarboxysiroheme + 2 CO2
12,18-Didecarboxysiroheme <=> Fe-coproporphyrin III
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine <=> Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine
Lutein <=> meso-Zeaxanthin
3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> Hapalindole H
3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> 12-epi-Hapalindole U
3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> 12-epi-Fischerindole U
S-Adenosyl-L-methionine + Adenine in mRNA <=> S-Adenosyl-L-homocysteine + N6-Methyladenine in mRNA
GDP-6-deoxy-alpha-D-altrose + Sordaricin <=> 4'-O-Demethylsordarin + GDP
4-Hydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3-Bromo-4-hydroxybenzoate + NADP+ + 2 H2O
3-Bromo-4-hydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 2,4-Dibromophenol + NADP+ + CO2 + 2 H2O
Deamino-NAD+ + HCO3- <=> AMP + Pyridinium-3,5-biscarboxylic acid mononucleotide
3,4-Dihydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3-Bromo-4,5-dihydroxybenzoate + NADP+ + 2 H2O
3-Bromo-4,5-dihydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3,5-Dibromobenzene-1,2-diol + NADP+ + CO2 + 2 H2O
Pyrrole-2-carbonyl-[pcp] + FADH2 + Cl- + Oxygen <=> 5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Cl- + Oxygen <=> 4,5-Dichloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
N-(4-Oxoglutaryl)-L-cysteinylglycine + H2O <=> 2-Oxoglutarate + Cys-Gly
cis-3-[2,2-Dichloro-1-(4-chlorophenyl)vinyl]-6-chlorocyclohexa-3,5-diene-1,2-diol + NAD+ <=> 1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene + NADH + H+
NAD+ + Glycine + Hydrogen sulfide <=> Nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
Pyrrole-2-carbonyl-[pcp] + FADH2 + Bromide + Oxygen <=> 5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Bromide + Oxygen <=> 4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Bromide + Oxygen <=> 3,4,5-Tribromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 5-Chloro-L-tryptophan + FAD + 2 H2O
L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6-Chloro-L-tryptophan + FAD + 2 H2O
D-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6-Chloro-D-tryptophan + FAD + 2 H2O
7-Chloro-L-tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6,7-Dichloro-L-tryptophan + FAD + 2 H2O
Anthranilate + N,N-Dimethyl-1,4-phenylenediamine + 2 NAD+ <=> Methyl red + 2 NADH + 2 H+
UDP-glucose + (E)-omega-(Methylthio)alkyl-thiohydroximate <=> UDP + Aliphatic desulfoglucosinolate
Kaempferol 3-O-glucoside + UDP-L-rhamnose <=> Kaempferol-3-O-rutinoside + UDP
Afzelin + UDP-glucose <=> Kaempferol 3-O-rhamnoside-7-O-glucoside + UDP
2-Methylquinolin-4-ol + trans,trans-Farnesyl diphosphate <=> Aurachin D + Diphosphate
Aurachin D + NADPH + H+ + Oxygen <=> Aurachin C + NADP+ + H2O
Aurachin B + NADPH + H+ + Oxygen <=> Aurachin B epoxide + NADP+ + H2O
Aurachin B + NADH + H+ + Oxygen <=> Aurachin B epoxide + NAD+ + H2O
Aurachin B epoxide <=> Aurachin A
L-Methionine + Indolepyruvate <=> 4-Methylthio-2-oxobutanoic acid + L-Tryptophan
ATP + L-Proline <=> Diphosphate + (L-Prolyl)adenylate
(L-Prolyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Prolyl-[pcp]
ATP + Pyridinium-3,5-biscarboxylic acid mononucleotide <=> Diphosphate + 5-Carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate
5-Carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate + [Protein]-L-cysteine <=> AMP + [Protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine
[Protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [Protein]-dehydroalanine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide
[Protein]-L-cysteine + Pyridinium-3,5-biscarboxylic acid mononucleotide + ATP <=> [Protein]-dehydroalanine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide + AMP + Diphosphate
ATP + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide <=> Diphosphate + 1-(5-O-Phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate
1-(5-O-Phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate + [Protein]-L-cysteine <=> AMP + [Protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine
[Protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [Protein]-dehydroalanine + Pyridinium-3,5-bisthiocarboxylate mononucleotide
[Protein]-L-cysteine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide + ATP <=> [Protein]-dehydroalanine + Pyridinium-3,5-biscarboxylic acid mononucleotide + AMP + Diphosphate
(2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 4-[(E)-2-Isocyanoethenyl]phenol + Succinate + 2 CO2 + H2O
(2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> (2E)-3-(4-Hydroxyphenyl)-2-isocyanoprop-2-enoate + Succinate + CO2 + H2O
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 3-[(Z)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 3-[(E)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O
Acetyl-CoA + L-Glutamate 5-semialdehyde <=> CoA + N-Acetyl-L-glutamate 5-semialdehyde
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] <=> Ornithine lipid + Acyl-carrier protein
2 2-Acetylphloroglucinol <=> 2,4-Diacetylphloroglucinol + Phloroglucinol
UDP-glucose + Phloretin <=> UDP + Phlorizin
Geranyl diphosphate + 3-[(Z)-2-Isocyanoethenyl]-1H-indole <=> 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + Diphosphate
Dihydrochanoclavine-I aldehyde + NADP+ <=> Chanoclavine-I aldehyde + NADPH + H+
Dihydrochanoclavine-I aldehyde + H+ <=> 6,8-Dimethyl-6,7-didehydroergoline + H2O
O-Phospho-L-serine + Thiosulfate <=> S-Sulfo-L-cysteine + Orthophosphate
Festuclavine <=> Fumigaclavine B
Chanoclavine-I aldehyde + H+ <=> 6,8-Dimethyl-6,7,8,9-tetradehydroergoline + H2O
2-O-(alpha-D-Mannosyl)-D-glycerate + H2O <=> D-Mannose + D-Glycerate
[SoxY protein]-S-sulfosulfanyl-L-cysteine + H2O <=> [SoxY protein]-S-sulfanyl-L-cysteine + Sulfate
[SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + H2O <=> [SoxY protein]-S-disulfanyl-L-cysteine + Sulfate
(R)-S-Adenosyl-L-methionine + H2O <=> Adenosine + L-Methionine
ATP + [SAMP]-Gly-Gly <=> Diphosphate + [SAMP]-Gly-Gly-AMP
UDP-glucuronate + Archaeal dolichyl alpha-D-glucosyl phosphate <=> UDP + Archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate
Cannabigerolate + Oxygen <=> Delta9-Tetrahydrocannabinolate + Hydrogen peroxide
Delta9-Tetrahydrocannabinolate <=> Dronabinol + CO2
Cannabidiolic acid <=> Cannabidiol + CO2
4-Dimethylallyl-L-abrine <=> Chanoclavine-I
3-Oxocholan-24-oyl-CoA + NAD+ <=> 3-Oxochol-4-en-24-oyl-CoA + NADH + H+
3-Oxochol-4-en-24-oyl-CoA + NAD+ <=> 3-Oxochola-4,6-dien-24-oyl-CoA + NADH + H+
12alpha-Hydroxy-3-oxocholan-24-oyl-CoA + NAD+ <=> 12alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
12alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+ <=> 12alpha-Hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + NADH + H+
7alpha,12alpha-Dihydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7alpha,12alpha-Dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
7alpha-Hydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
7beta-Hydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7beta-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
Dihydro-4-coumaroyl-CoA + NADP+ <=> p-Coumaroyl-CoA + NADPH + H+
Dihydroferuloyl-CoA + NADP+ <=> Feruloyl-CoA + NADPH + H+
8-Amino-8-demethylriboflavin 5'-phosphate + H2O <=> 8-Amino-8-demethylriboflavin + Orthophosphate
1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3-phosphate + Orthophosphate
1-O-(2-Acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + H2O <=> 1-O-[2-(Acetylamino)-2-deoxy-alpha-D-glucopyranosyl]-D-myo-Inositol + Orthophosphate
Coniferyl alcohol <=> (+)-Pinoresinol
Deoxypodophyllotoxin <=> Podophyllotoxin
6alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Costunolide + H2O
Crocetin dialdehyde <=> Crocetin
(3S)-3-Hydroxycyclocitral <=> Picrocrocin
Picrocrocin <=> Safranal
17-O-Acetylnorajmaline + S-Adenosyl-L-methionine <=> 17-O-Acetylajmaline + S-Adenosyl-L-homocysteine
(9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid + H2O <=> 9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid
9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid + NADPH + H+ <=> 9-Hydroxy-12-oxo-15(Z)-octadecenoic acid + NADP+
Psilocybin <=> Psilocin
Coniferyl alcohol <=> (-)-Pinoresinol
L-Galactonate + NAD+ <=> D-Tagaturonate + NADH + H+
5-Aminosalicylate + Oxygen <=> (2Z,4E)-4-Amino-6-oxohepta-2,4-dienedioate
ATP + Medium-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Medium-chain acyl-[acyl-carrier protein]
(-)-Bornane-2,5-dione + Reduced FMN + Oxygen <=> (-)-5-Oxo-1,2-campholide + FMN + H2O
L-Tyrosine + D-Ribulose 5-phosphate <=> (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O
L-Tryptophan + D-Ribulose 5-phosphate <=> (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O
N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + Ammonia <=> 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + H2O
L-Galactono-1,5-lactone + H2O <=> L-Galactonate
L-Galactose + NADP+ <=> L-Galactono-1,5-lactone + NADPH + H+
S-Adenosyl-L-methionine + 1,6-Didemethyltoxoflavin <=> S-Adenosyl-L-homocysteine + Reumycin
S-Adenosyl-L-methionine + Reumycin <=> S-Adenosyl-L-homocysteine + Toxoflavine
Octanoyl-CoA + 2-O-[alpha-D-Glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate <=> CoA + 2-O-[6-O-Octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate
UDP-glucose + 2-Acylphloroglucinol <=> UDP + 2-Acylphloroglucinol 1-O-beta-D-glucoside
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine <=> 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine <=> 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine
Hapalindole U + 2-Oxoglutarate + Oxygen + Cl- <=> Hapalindole G + Succinate + CO2 + H2O
12-epi-Fischerindole U + 2-Oxoglutarate + Oxygen + Cl- <=> 12-epi-Fischerindole G + Succinate + CO2 + H2O
L-Threonyl-[L-threonyl-carrier protein] + 2-Oxoglutarate + Oxygen + Cl- <=> 4-Chloro-L-threonyl-[L-threonyl-carrier protein] + Succinate + CO2 + H2O
beta-Carotene <=> Echinenone
Echinenone <=> Canthaxanthin
Ammonia + HCO3- <=> Carbamate + H2O
Palmitoylphosphatidylcholine + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate <=> 2-Acyl-sn-glycero-3-phosphocholine + Lipid IVB
L-Cysteine-S-conjugate + H2O <=> Thiol + Ammonia + Pyruvate
Octadecanoyl-[acyl-carrier protein] + H. pylori KDO2-lipid IVA <=> Stearoyl-KDO2-lipid IVA + Acyl-carrier protein
Tetradecanoyl-[acp] + (9Z)-Hexadec-9-enoyl-KDO2-lipid IV(A) <=> Palmitoleoyl-myristoyl-KDO2-lipid A + Acyl-carrier protein
2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate + H2O <=> Deacyl-lipid IVA + (R)-3-Hydroxymyristic acid
Palmitoylphosphatidylcholine + Deacyl-lipid IVA <=> 2-Acyl-sn-glycero-3-phosphocholine + Deacyl-lipid IVB
Palmitoylphosphatidylcholine + Lipid IIA <=> 2-Acyl-sn-glycero-3-phosphocholine + Lipid IIB
DIMBOA-glucoside + H2O <=> DIMBOA + D-Glucose
DIBOA-glucoside + H2O <=> DIBOA + D-Glucose
Oxaloacetate + 2 Sodium cation <=> Pyruvate + CO2 + 2 Sodium cation
Naringenin + S-Adenosyl-L-methionine <=> Isosakuranetin + S-Adenosyl-L-homocysteine
Cadaverine + 2-Oxoglutarate <=> 5-Aminopentanal + L-Glutamate
5-Aminopentanal + NAD+ + H2O <=> 5-Aminopentanoate + NADH + H+
Glutarate + 2-Oxoglutarate + Oxygen <=> (S)-2-Hydroxyglutarate + Succinate + CO2
D-Glucosamine 6-phosphate <=> D-Galactosamine 6-phosphate
D-Galactosamine 6-phosphate <=> alpha-D-Galactosamine 1-phosphate
Scopoletin + 2-Oxoglutarate + Oxygen <=> Fraxetin + Succinate + CO2
L-Tyrosinal + NADP+ + AMP + Diphosphate <=> L-Tyrosine + NADPH + H+ + ATP
Meromycolyl-[acyl-carrier protein] + NAD+ <=> trans-Delta2-Meromycolyl-[acyl-carrier protein] + NADH + H+
Staphylopine + NADP+ + H2O <=> (2S)-2-Amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + Pyruvate + NADPH + H+
Acyl-[acyl-carrier protein] + Orthophosphate <=> Acyl phosphate + Acyl-carrier protein
Acyl phosphate + sn-Glycerol 3-phosphate <=> 1-Acyl-sn-glycerol 3-phosphate + Orthophosphate
Acetyl-CoA + alpha-D-Galactosamine 1-phosphate <=> CoA + N-Acetyl-alpha-D-galactosamine 1-phosphate
2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate <=> D-Glucose 1-phosphate + Glycerol
ATP + 5-Amino-1-(beta-D-ribosyl)imidazole <=> ADP + Aminoimidazole ribotide
ATP + Cytidine 5'-diphosphoramidate <=> ADP + Cytidine 3'-phospho-5'-diphosphoramidate
CTP + N5-Phospho-L-glutamine <=> Diphosphate + N5-(Cytidine 5'-diphosphoramidyl)-L-glutamine
D-Xylono-1,4-lactone 5-phosphate + H2O <=> 5-Phospho-D-xylonate
L-Arabino-1,4-lactone 5-phosphate + H2O <=> 5-Phospho-L-arabinate
2-O-(alpha-D-Glucopyranosyl)-D-glycerate + H2O <=> D-Glucose + D-Glycerate
N5-(Cytidine 5'-diphosphoramidyl)-L-glutamine + H2O <=> Cytidine 5'-diphosphoramidate + L-Glutamate
(R)-3-(3,4-Dihydroxyphenyl)lactate + NADP+ <=> 3-(3,4-Dihydroxyphenyl)pyruvate + NADPH + H+
1,4-Dihydroxy-2-naphthoate <=> 2-Carboxy-1,4-naphthoquinone
Phytyl diphosphate + 2-Carboxy-1,4-naphthoquinone <=> 2-Phytyl-1,4-naphthoquinone + Diphosphate + CO2
(R)-(Indol-3-yl)lactate + NAD+ <=> Indolepyruvate + NADH + H+
cis-3-Alkyl-4-alkyloxetan-2-one <=> cis-Alkene + CO2
ent-Copalyl diphosphate <=> Dolabradiene + Diphosphate
trans,trans-Farnesyl diphosphate + 2 H2O <=> 7-epi-ent-Eudesmane-5,11-diol + Diphosphate
trans,trans-Farnesyl diphosphate <=> alpha-Selinene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-5-Epieremophilene + Diphosphate
Narcotoline + S-Adenosyl-L-methionine <=> alpha-Narcotine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + Nocamycin E <=> S-Adenosyl-L-homocysteine + Nocamycin I
S-Adenosyl-L-methionine + Xanthohumol <=> S-Adenosyl-L-homocysteine + 4-O-Methylxanthohumol
Isopyridoxal + NAD+ + H2O <=> 3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADH + H+
6alpha,8beta-Dihydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Eupatolide + H2O
Geranylgeranyl diphosphate <=> beta-Pinacene + Diphosphate
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate + H2O <=> AMP + Diphosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
ATP + UDP-N-acetylmuramoyl-L-alanine + L-Glutamate <=> ADP + Orthophosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate
8alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate <=> 8-epi-Inunolide + H2O
Prephytoene diphosphate + NADPH + H+ <=> Lycopaoctaene + Diphosphate + NADP+
2 Geranylgeranyl diphosphate + NADPH + H+ <=> Lycopaoctaene + 2 Diphosphate + NADP+
Dimethylallyl diphosphate + Lycopene + H2O <=> Dihydroisopentenyldehydrorhodopin + Diphosphate
Dimethylallyl diphosphate + Isopentenyldehydrorhodopin + H2O <=> Dihydrobisanhydrobacterioruberin + Diphosphate
Long-chain acyl-CoA + alpha,alpha-Trehalose <=> 2-(Long-chain-fatty acyl)-trehalose + CoA
Mycolipenoyl-CoA + 2-(Long-chain-fatty acyl)-trehalose <=> 2-(Long-chain-fatty acyl)-3-mycolipenoyl-trehalose + CoA
Medium-chain 3-oxoacyl-[acyl-carrier protein] + Glycerone phosphate <=> 2-Oxo-3-(phosphooxy)propyl 3-oxoalkanoate + Acyl-carrier protein
UDP-glucose + 2'-Hydroxy-beta-oxodihydrochalcone <=> UDP + 3'-(beta-D-Glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone
5-Methyl-H4SPT + Coenzyme M + 2 Sodium cation(side 1) <=> Tetrahydrosarcinapterin + 2-(Methylthio)ethanesulfonate + 2 Sodium cation(side 2)
Dolichol + NADP+ <=> Polyprenol + NADPH + H+
ATP + Malonate + CoA <=> AMP + Diphosphate + Malonyl-CoA
Isoeugenol + Oxygen <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetaldehyde
Indole-3-acetate <=> Skatole + CO2
D-Ornithine <=> Putrescine + CO2
D-Lysine <=> Cadaverine + CO2
p-Coumaroyl-CoA + 2-Oxoglutarate + Oxygen <=> 2,4-Dihydroxycinnamoyl-CoA + Succinate + CO2
(4R)-4,2'-Dihydroxyisoflavan <=> Pterocarpan + H2O
ATP + L-2,3-Diaminopropanoate + Citrate <=> AMP + Diphosphate + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate
2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate <=> 2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO2
2,4-Dihydroxycinnamoyl-CoA <=> Umbelliferone + CoA
ATP + 2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + L-2,3-Diaminopropanoate <=> AMP + Diphosphate + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate
ATP + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-Oxoglutarate <=> AMP + Diphosphate + Staphyloferrin B
L-Histidine <=> D-Histidine
6-Sulfo-alpha-D-quinovose <=> 6-Sulfo-beta-D-quinovose
Protein lysine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3S)-3-hydroxy-L-lysine + Succinate + CO2
Dimethyl sulfide + NADH + H+ + Oxygen <=> Dimethyl sulfoxide + NAD+ + H2O
Dimethyl sulfoxide + NADH + H+ + Oxygen <=> Dimethyl sulfone + NAD+ + H2O
Long-chain acyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Long-chain fatty acid
Cyanuric acid + H2O <=> 1-Carboxybiuret
1-Carboxybiuret + H2O <=> Urea-1,3-dicarboxylate + Ammonia
Urea-1,3-dicarboxylate <=> Urea-1-carboxylate + CO2
1-Carboxybiuret <=> Biuret + CO2
S-Adenosyl-L-methionine + Demethylluteothin <=> S-Adenosyl-L-homocysteine + Luteothin
2 GDP-mannose + Bis(myo-inositol) 1,3'-phosphate <=> 2 GDP + 2-O-(beta-D-Mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate
GDP-mannose + Bis(myo-inositol) 1,3'-phosphate <=> GDP + 2-O-(beta-D-Mannosyl)-bis(myo-inositol) 1,3'-phosphate
GDP-mannose + 2-O-(beta-D-Mannosyl)-bis(myo-inositol) 1,3'-phosphate <=> GDP + 2-O-(beta-D-Mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate
S-Adenosyl-L-methionine + D-Histidine <=> (2S)-2-Amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + 5'-Methylthioadenosine
ADP + L-Serine <=> AMP + O-Phospho-L-serine
(2E,5S,6E,8E,10E)-1-Aminododeca-2,6,8,10-tetraen-5-ol + Pyruvate <=> (2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + L-Alanine
ATP + L-Serine <=> ADP + O-Phospho-L-serine
Cyclic di-3',5'-adenylate + H2O <=> 5'-O-Phosphonoadenylyl-(3'->5')-adenosine
5'-O-Phosphonoadenylyl-(3'->5')-adenosine + H2O <=> 2 AMP
3-O-Acetylpapaveroxine + H2O <=> Narcotine hemiacetal + Acetate
3 3'-(Hydroxy)phthioceranyl-2'-palmitoyl(stearoyl)-2-O-sulfo-alpha,alpha-trehalose <=> 3,6,6'-Tris-(hydroxy)phthioceranyl-2-palmitoyl(stearoyl)-2'-sulfo-alpha,alpha-trehalose + 2 2'-Palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose
Sucrose + Dextran <=> D-Fructose + (1->6)-alpha-D-Glucan containing a (1->3)-alpha-D-glucose branch
N3-Fumaroyl-L-2,3-diaminopropanoate + L-Glutamine + ATP + H2O <=> 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Glutamate + AMP + Diphosphate
D-Ornithine + Citrate + ATP <=> N5-Citryl-D-ornithine + AMP + Diphosphate
N5-Citryl-D-ornithine + Citrate + ATP <=> Staphyloferrin A + AMP + Diphosphate
Propanoyl-CoA + Oxygen <=> Propenoyl-CoA + Hydrogen peroxide
3beta-Hydroxy-4,4-dimethylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + NAD+ + H2O
3beta-Hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4beta-formyl-4alpha-methylsteroid + NAD+ + 2 H2O
3beta-Hydroxy-4beta-formyl-4alpha-methylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD+ + H2O
3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD+ <=> 4alpha-Methyl-3-oxosteroid + NADH + CO2 + H+
3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP+ <=> 4alpha-Methyl-3-oxosteroid + NADPH + CO2 + H+
Geranylgeranyl diphosphate <=> Hydropyrene + Diphosphate
Geranylgeranyl diphosphate + H2O <=> Hydropyrenol + Diphosphate
Geranylgeranyl diphosphate <=> Isoelisabethatriene + Diphosphate
3beta-Hydroxysteroid-4alpha-carboxylate + NAD+ <=> 3-Oxosteroid + NADH + CO2 + H+
3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + NAD+ <=> Cycloeucalenone + NADH + CO2 + H+
3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate + NAD+ <=> Episterone + NADH + CO2 + H+
4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + NAD+ <=> Avenastenone + NADH + CO2 + H+
UDP-glucose + Protopanaxadiol <=> UDP + Ginsenoside C-K
UDP-glucose + Protopanaxadiol <=> UDP + (20S)-Ginsenoside Rh2
UDP-glucose + Ginsenoside C-K <=> UDP + Ginsenoside F2
UDP-glucose + (20S)-Ginsenoside Rh2 <=> UDP + Ginsenoside Rg3
UDP-glucose + Ginsenoside F2 <=> UDP + Ginsenoside Rd
UDP-glucose + Ginsenoside F1 <=> UDP + Ginsenoside Rg1
UDP-glucose + Protopanaxatriol <=> UDP + Ginsenoside Rh1
UDP-glucose + Oleanolic acid <=> UDP + Oleanolate 3-O-beta-D-glucoside
3''-O-Acetyl-ADP-D-ribose + H2O <=> ADP-ribose + Acetate
O-Acetyl-ADP-ribose + H2O <=> ADP-ribose + Acetate
2,4-Diacetylphloroglucinol + H2O <=> 2-Acetylphloroglucinol + Acetate
ATP + Octadecanoic acid <=> Diphosphate + (Stearoyl)adenylate
(Stearoyl)adenylate + Peptidyl-carrier protein <=> AMP + Stearoyl-[(hydroxy)phthioceranic acid synthase]
ATP + Octadecanoic acid + Peptidyl-carrier protein <=> AMP + Diphosphate + Stearoyl-[(hydroxy)phthioceranic acid synthase]
ATP + Hexadecanoic acid <=> Diphosphate + (Palmitoyl)adenylate
(Palmitoyl)adenylate + Peptidyl-carrier protein <=> AMP + Palmitoyl-[(hydroxy)phthioceranic acid synthase]
ATP + Hexadecanoic acid + Peptidyl-carrier protein <=> AMP + Diphosphate + Palmitoyl-[(hydroxy)phthioceranic acid synthase]
Cycloeucalenone + NADPH + H+ <=> Cycloeucalenol + NADP+
Episterone + NADPH + H+ <=> Episterol + NADP+
Avenastenone + NADPH + H+ <=> Delta7-Avenasterol + NADP+
3beta-Hydroxysteroid + NADP+ <=> 3-Oxosteroid + NADPH + H+
4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> Zymosterone + NADPH + H+ + CO2
Zymosterone + NADPH + H+ <=> Zymosterol + NADP+
3beta-Hydroxysteroid-4alpha-carboxylate + NADP+ <=> 3-Oxosteroid + CO2 + NADPH + H+
L-Lysine + 2-Oxoglutarate + Oxygen + Cl- + H+ <=> 4-Chloro-L-lysine + Succinate + CO2 + H2O
2-Amino-4-chloro-4-pentenoic acid <=> L-Propargylglycine + Cl- + H+
L-Propargylglycine + L-Glutamate <=> gamma-L-Glutamyl-L-propargylglycine
gamma-L-Glutamyl-L-propargylglycine + 2-Oxoglutarate + Oxygen <=> L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + Succinate + CO2
L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + H2O <=> L-beta-Ethynylserine + L-Glutamate
Cyclo(L-Trp-L-Phe) + S-Adenosyl-L-methionine <=> N-Methyl-cyclo(L-Trp-L-Phe) + S-Adenosyl-L-homocysteine
2 N-Methyl-cyclo(L-Trp-L-Phe) <=> (-)-Ditryptophenaline
Anthranilate + L-Tryptophan + L-Alanine + 3 ATP <=> Fumiquinazoline F + 3 AMP + 3 Diphosphate + H2O
Fumiquinazoline F-indoline-2',3'-diol + L-Alanine + ATP <=> Fumiquinazoline A + AMP + Diphosphate + H2O
Fumiquinazoline A + Oxygen <=> Fumiquinazoline C + Hydrogen peroxide
Fumiquinazoline C <=> Fumiquinazoline D
[Glycine cleavage system H]-N6-octanoyl-L-lysine + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine
Lipoylprotein + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + Enzyme N6-(lipoyl)lysine
Octanoyl-[acp] + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + Acyl-carrier protein
Octanoyl-[acp] + Glycine cleavage system H <=> [Glycine cleavage system H]-N6-octanoyl-L-lysine + Acyl-carrier protein
ATP + Octanoic acid + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + AMP + Diphosphate
Octanoyl-[acp] + CoA <=> Octanoyl-CoA + Acyl-carrier protein
Octanoyl-CoA + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + CoA
Dihydrolipoylprotein + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + Enzyme N6-(dihydrolipoyl)lysine
ATP + (R)-Lipoate + Glycine cleavage system H <=> Lipoylprotein + AMP + Diphosphate
ATP + Dihydrolipoate <=> Dihydrolipoyl-AMP + Diphosphate
Dihydrolipoyl-AMP + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP + 2 H+
L-Tryptophan + L-Histidine <=> Histidyltryptophyldiketopiperazine
Histidyltryptophyldiketopiperazine + Dimethylallyl diphosphate <=> Roquefortine D + Diphosphate
Histidyltryptophyldiketopiperazine <=> Dehydrohistidyltryptophyldiketopiperazine
Dehydrohistidyltryptophyldiketopiperazine + Dimethylallyl diphosphate <=> Roquefortine C + Diphosphate
Roquefortine D <=> Roquefortine C
Glandicoline B + S-Adenosyl-L-methionine <=> Meleagrin + S-Adenosyl-L-homocysteine
N1-Hydroxy-roquefortine C + S-Adenosyl-L-methionine <=> Roquefortine F + S-Adenosyl-L-homocysteine
ATP + (R)-Lipoate + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP + Diphosphate
Lipoyl-AMP + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP
Hydroxymethylphosphonate + Oxygen <=> Formate + Orthophosphate
Methylphosphonate + 2-Oxoglutarate + Oxygen <=> Hydroxymethylphosphonate + Succinate + CO2
Cyclohexane-1-carbonyl-CoA + NADP+ <=> Cyclohex-1-ene-1-carbonyl-CoA + NADPH + H+
Fe-coproporphyrin III + Hydrogen peroxide <=> Harderoheme III + CO2 + 2 H2O
Harderoheme III + Hydrogen peroxide <=> Heme + CO2 + 2 H2O
trans,trans-Farnesyl diphosphate + H2O <=> Valerianol + Diphosphate
2 Methanethiol + NAD+ <=> Dimethyl disulfide + NADH + H+
S-Adenosyl-L-methionine + Cycloartenol <=> S-Adenosyl-L-homocysteine + Cyclolaudenol
Protein N6,N6,N6-trimethyl-L-lysine + 2 2-Oxoglutarate + 2 Oxygen <=> Protein N6-methyl-L-lysine + 2 Succinate + 2 Formaldehyde + 2 CO2
Protein N6,N6,N6-trimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein N6,N6-dimethyl-L-lysine + Succinate + Formaldehyde + CO2
Stearoyl-CoA + 2-Sulfotrehalose <=> 2-O-Sulfo-2'-stearoyl-alpha,alpha-trehalose + CoA
Palmitoyl-CoA + 2-Sulfotrehalose <=> 2-O-Sulfo-2'-palmitoyl-alpha,alpha-trehalose + CoA
UDP-glucose + Enterochelin <=> UDP + Monoglucosyl-enterobactin
UDP-glucose + Monoglucosyl-enterobactin <=> UDP + Diglucosyl-enterobactin
UDP-glucose + Diglucosyl-enterobactin <=> UDP + Triglucosyl-enterobactin
GDP-mannose + Very-long-chain inositol phospho-(2'R)-2'-hydroxyphytoceramide <=> Very-long-chain mannosylinositol phospho-(2'R)-2'-hydroxyphytoceramide + GDP
Enterochelin + H2O <=> N-(2,3-Dihydroxybenzoyl)-L-serine trimer
Triglucosyl-enterobactin + H2O <=> Triglucosyl-(2,3-dihydroxybenzoylserine)3
Diglucosyl-enterobactin + H2O <=> Diglucosyl-(2,3-dihydroxybenzoylserine)3
Monoglucosyl-enterobactin + H2O <=> Monoglucosyl-(2,3-dihydroxybenzoylserine)3
N-Acyl-L-glutamine + H2O <=> L-Glutamine + Carboxylate
Bilirubin + Oxidised coenzyme F420-(gamma-Glu)n <=> Biliverdin + Reduced coenzyme F420-(gamma-Glu)n
(+)-cis,cis-Nepetalactol + NAD+ <=> (+)-cis,cis-Nepetalactone + NADH + H+
cis-trans-Nepetalactol + NAD+ <=> Nepetalactone cis-trans-form + NADH + H+
ATP + Isophthalate + CoA <=> AMP + Diphosphate + Isophthalyl-CoA
Isophthalyl-CoA <=> Benzoyl-CoA + CO2
(R)-Phenyllactyl-CoA <=> (E)-Cinnamoyl-CoA + H2O
(R)-3-(4-Hydroxyphenyl)lactoyl-CoA <=> p-Coumaroyl-CoA + H2O
(R)-3-(Indol-3-yl)lactoyl-CoA <=> 3-(Indol-3-yl)acryloyl-CoA + H2O
Pre-sodorifen diphosphate <=> Sodorifen + Diphosphate
4-Amino-4-deoxychorismate <=> 4-Amino-4-deoxyprephenate
p-Coumaroyl-CoA + (R)-3-(4-Hydroxyphenyl)lactate <=> 4-Coumarate + (R)-3-(4-Hydroxyphenyl)lactoyl-CoA
3-(Indol-3-yl)acryloyl-CoA + (R)-(Indol-3-yl)lactate <=> 3-Indoleacrylate + (R)-3-(Indol-3-yl)lactoyl-CoA
ATP + Marinolic acid <=> AMP + Diphosphate + Marinoloyl-CoA
ATP + Pseudomonic acid <=> AMP + Diphosphate + Pseudomonoyl-CoA
Long-chain acyl-CoA + Sterol <=> CoA + Long-chain 3-hydroxysterol ester
2-Hydroxyethylphosphonate + CTP <=> Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Diphosphate
Cytidine 5'-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + H2O <=> (S)-2-Hydroxypropylphosphonate + CMP
Indole-3-acetate + 2-Oxoglutarate + Oxygen <=> 2-Oxoindole-3-acetate + Succinate + CO2
D-Apiofuranose + NAD+ <=> D-Apionolactone + NADH + H+
D-Apionate + NAD+ <=> 3-Oxoisoapionate + NADH + H+
Phenylacetic acid <=> Toluene + CO2
L-Arginine + L-Lysine <=> L-Ornithine + Homoarginine
L-Glutamine + 4-Methylthio-2-oxobutanoic acid <=> 2-Oxoglutaramate + L-Methionine
2 Oxygen + Ubiquinol <=> 2 Superoxide + Ubiquinone + 2 H+
7-Deoxycylindrospermopsin + 2-Oxoglutarate + Oxygen <=> Cylindrospermopsin + Succinate + CO2
7-Deoxycylindrospermopsin + 2-Oxoglutarate + Oxygen <=> 7-epi-Cylindrospermopsin + Succinate + CO2
Stachydrine + NADH + H+ + Oxygen <=> N-Methyl-L-proline + Formaldehyde + NAD+ + H2O
Stachydrine + NADPH + H+ + Oxygen <=> N-Methyl-L-proline + Formaldehyde + NADP+ + H2O
(Indol-3-yl)acetyl-L-aspartate + H2O <=> Indole-3-acetate + L-Aspartate
R-S-Cysteinylglycine + H2O <=> L-Cysteine-S-conjugate + Glycine
Ethyl acetate + H2O <=> Acetate + Ethanol
Isoamyl acetate + H2O <=> 3-Methylbutanol + Acetate
(6E)-8-Oxogeranial + NADH + H+ <=> (S)-8-Oxocitronellyl enol + NAD+
(6E)-8-Oxogeranial + NADPH + H+ <=> (S)-8-Oxocitronellyl enol + NADP+
(S)-8-Oxocitronellyl enol <=> cis-trans-Nepetalactol
(S)-8-Oxocitronellyl enol <=> (+)-cis,cis-Nepetalactol
(+)-(1S,2S)-Pseudoephedrine + NAD+ <=> (S)-2-(Methylamino)-1-phenylpropan-1-one + NADH + H+
4-Amino-4-deoxyprephenate + NAD+ <=> 3-(4-Aminophenyl)pyruvate + NADH + CO2 + H+
S-Adenosyl-L-methionine + trans,trans-Farnesyl diphosphate <=> S-Adenosyl-L-homocysteine + Pre-sodorifen diphosphate
Sucrose + 1,3-alpha-D-Glucan(n) <=> D-Fructose + 1,3-alpha-D-Glucan(n+1)
Sucrose + Dextran <=> D-Fructose + (1->6)-alpha-D-Glucan containing a (1->2)-alpha-D-glucose branch
GDP-mannose + 1,2-beta-Oligomannan(n) <=> GDP + 1,2-beta-Oligomannan(n+1)
ATP + Amicoumacin A <=> ADP + Amicoumacin A 2-phosphate
Amicoumacin A 2-phosphate + H2O <=> Amicoumacin A + Orthophosphate
8-Oxo-GTP + H2O <=> 8-Oxo-GDP + Orthophosphate
8-Oxo-dGTP + H2O <=> 8-Oxo-dGDP + Orthophosphate
1-Acyl-sn-glycero-3-phosphoserine + H2O <=> Glycerophosphoserine + Fatty acid
Dibenzothiophene-5,5-dioxide + FMN-N5-peroxide <=> 2'-Hydroxybiphenyl-2-sulfinate + FMN-N5-oxide
FMN-N5-oxide + NADH <=> FMN + H2O + NAD+ + H+
L-Phenylalanine + Tetrahydropteridine + Oxygen <=> L-Tyrosine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
L-Tyrosine + Tetrahydropteridine + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
L-Tryptophan + Tetrahydropteridine + Oxygen <=> 5-Hydroxy-L-tryptophan + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
L-Phenylalanine + Tetrahydropteridine + Oxygen <=> 3-Hydroxy-L-phenylalanine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
Uracil + Reduced FMN + Oxygen + NADH <=> Ureidoacrylate + H2O + FMN + NAD+ + H+
Uracil + FMN-N5-peroxide <=> Ureidoacrylate + FMN-N5-oxide
Thymine + Reduced FMN + Oxygen + NADH <=> Methylureidoacrylate + H2O + FMN + NAD+ + H+
Thymine + FMN-N5-peroxide <=> Methylureidoacrylate + FMN-N5-oxide
5,10-Methylenetetrahydrofolate + tRNA containing uridine at position 54 + NADH + H+ <=> Tetrahydrofolate + tRNA containing ribothymidine at position 54 + NAD+
Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-D-glucose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose
UDP-2-acetamido-2,6-dideoxy-beta-L-mannose <=> UDP-2-acetamido-2,6-dideoxy-beta-L-glucose
UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose <=> UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-galactose
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NADP+
UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + D-Alanine <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucopyranose + H2O
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucopyranose <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose + H2O <=> 2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + UDP
Ephedrine + NAD+ <=> (S)-2-(Methylamino)-1-phenylpropan-1-one + NADH + H+
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + Acetyl-CoA <=> UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idose + CoA
5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + CTP <=> CMP-5-N-acetyl-7-N-(D-alanyl)-legionaminic acid + Diphosphate
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idose <=> UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-gulose
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-gulose + H2O <=> 2,4-Diacetamido-2,4,6-trideoxy-beta-L-gulose + UDP
2,4-Diacetamido-2,4,6-trideoxy-beta-L-gulose + Phosphoenolpyruvate + H2O <=> 5,7-Diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid + Orthophosphate
Feruloyl-CoA + H2O <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA
2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> 5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + Orthophosphate
CTP + 5,7-Diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid <=> CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid + Diphosphate
[Sulfatase]-L-serine + S-Adenosyl-L-methionine <=> [Sulfatase]-3-oxo-L-alanine + 5'-Deoxyadenosine + L-Methionine
Thioredoxin + ROOH <=> Thioredoxin disulfide + H2O + ROH
ATP + L-Arginine <=> Diphosphate + (L-Arginyl)adenylate
L-Arginine + Peptidyl-carrier protein + ATP <=> L-Arginyl-[pcp] + AMP + Diphosphate
(L-Arginyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Arginyl-[pcp]
ATP + 3,4-Dihydroxybenzoate + Aryl-carrier protein <=> AMP + Diphosphate + 3,4-Dihydroxybenzoyl-[aryl-carrier protein]
ATP + 3,4-Dihydroxybenzoate <=> Diphosphate + (3,4-Dihydroxybenzoyl)adenylate
(3,4-Dihydroxybenzoyl)adenylate + Aryl-carrier protein <=> AMP + 3,4-Dihydroxybenzoyl-[aryl-carrier protein]
2 Glutathione + ROOH <=> Glutathione disulfide + H2O + ROH
NADH + ROOH + H+ <=> NAD+ + H2O + ROH
Selenophosphoric acid + Geranyl diphosphate + tRNA containing 5-[(methylamino)methyl]-2-thiouridylate + H2O <=> 5-Methylaminomethyl-2-selenouridine in tRNA + (2E)-3,7-Dimethylocta-2,6-diene-1-thiol + Diphosphate + Orthophosphate
Geranyl diphosphate + tRNA containing 5-[(methylamino)methyl]-2-thiouridylate <=> 5-Methylaminomethyl-2-(S-geranyl)thiouridine in tRNA + Diphosphate
Selenophosphoric acid + 5-Methylaminomethyl-2-(S-geranyl)thiouridine in tRNA <=> 5-Methylaminomethyl-2-(Se-phospho)selenouridine in tRNA + (2E)-3,7-Dimethylocta-2,6-diene-1-thiol
5-Methylaminomethyl-2-(Se-phospho)selenouridine in tRNA + H2O <=> 5-Methylaminomethyl-2-selenouridine in tRNA + Orthophosphate
UDP-N-acetyl-beta-L-fucosamine <=> UDP-2,6-dideoxy-2-acetamidino-beta-L-galactose
(2R)-2-Hydroxy fatty acid + Oxygen <=> Fatty acid + H2O + CO2
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate <=> UDP-2,3-dideoxy-2-acetamido-3-acetamidino-alpha-D-mannuronic acid
NADPH + H2O <=> NADH + Orthophosphate
S-Inosyl-L-homocysteine + H2O <=> Inosine + L-Homocysteine
XTP + H2O <=> XDP + Orthophosphate
UDP-N-acetyl-D-galactosaminuronic acid + ATP + L-Glutamine + H2O <=> UDP-2-acetamido-2-deoxy-alpha-D-galacturonamide + AMP + L-Glutamate + Diphosphate
1-Alkyl-sn-glycerol + Tetrahydropteridine + Oxygen <=> 1-Hydroxyalkyl-sn-glycerol + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
ADP + D-Glucosamine <=> AMP + D-Glucosamine 6-phosphate
8-Oxo-GDP + H2O <=> 8-Oxo-GMP + Orthophosphate
Spermidine + Citrate + ATP <=> N-Citryl-spermidine + AMP + Diphosphate
N-Citryl-spermidine + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine + Aryl-carrier protein
N-Citryl-spermidine + Spermidine + ATP <=> N8,N'8-Citryl-bis(spermidine) + AMP + Diphosphate
N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine + Spermidine + ATP <=> N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + AMP + Diphosphate
N8,N'8-Citryl-bis(spermidine) + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + Aryl-carrier protein
N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> Petrobactin + Aryl-carrier protein
[Protein]-N6-[(R)-dihydrolipoyl]-L-lysine + ROOH <=> Protein N6-(lipoyl)lysine + H2O + ROH
Enzyme N6-(dihydrolipoyl)lysine + ROOH <=> Enzyme N6-(lipoyl)lysine + H2O + ROH
UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-mannose + NADP+
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate <=> UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + 2-Oxoglutarate
GDP-glucose + D-Mannose 1-phosphate <=> D-Glucose 1-phosphate + GDP-mannose
GTP + Dephospho-CoA <=> GDP + CoA
3-Oxoisoapionate <=> L-Erythrulose + CO2
3-Oxoisoapionate 4-phosphate <=> Erythrulose 1-phosphate + CO2
L-Tyrosine + Hydrogen peroxide <=> 3,4-Dihydroxy-L-phenylalanine + H2O
5-Deoxy-D-ribulose 1-phosphate <=> Glycerone phosphate + Acetaldehyde
S-Methyl-5-thio-D-ribulose 1-phosphate <=> Glycerone phosphate + (2-Methylthio)acetaldehyde
[(1R)-1-Hydroxy-2-(trimethylamino)ethyl]phosphonate + Oxygen <=> Betaine + Orthophosphate
[2-(Trimethylamino)ethyl]phosphonate + 2-Oxoglutarate + Oxygen <=> [(1R)-1-Hydroxy-2-(trimethylamino)ethyl]phosphonate + Succinate + CO2
ATP + 3-Oxoisoapionate <=> ADP + 3-Oxoisoapionate 4-phosphate
3,5,6-Trichloropyridin-2-ol + FADH2 + Oxygen <=> 3,6-Dichloropyridine-2,5-dione + Cl- + FAD + H2O
3,6-Dichloropyridine-2,5-diol + FADH2 + Oxygen <=> 6-Chloro-3-hydroxypyridine-2,5-dione + Cl- + FAD + H2O
6-Chloropyridine-2,3,5-triol + FADH2 + Oxygen <=> 3,6-Dihydroxypyridine-2,5-dione + Cl- + FAD + H2O
trans-2,3-Dehydroacyl-CoA + NADP+ <=> (2E,4Z)-2,4-Dienoyl-CoA + NADPH + H+
5'-Deoxyadenosine + H2O <=> 5-Deoxy-D-ribose + Adenine
4-Hydroxy-3-methoxy-benzaldehyde + L-Alanine <=> Vanillylamine + Pyruvate
Methylureidoacrylate + H2O <=> Methylaminoacrylate + CO2 + Ammonia
Methylureidoacrylate + H2O <=> Methylaminoacrylate + Carbamate
Ureidoacrylate + H2O <=> Aminoacrylate + CO2 + Ammonia
(6E)-8-Methylnon-6-enoyl-CoA + Vanillylamine <=> Capsaicin + CoA
8-Methyl-6-nonenoic acid <=> (6E)-8-Methylnon-6-enoyl-CoA
(3E)-3-Enoyl-CoA + NADP+ <=> (2E,4E)-2,4-Dienoyl-CoA + NADPH + H+
(3E)-3-Enoyl-CoA + NADP+ <=> (2E,4Z)-2,4-Dienoyl-CoA + NADPH + H+
S-Adenosyl-L-methionine + 3,3'-Di-O-methyl-4alpha-mannobiose <=> S-Adenosyl-L-homocysteine + 1,3,3'-Tri-O-methyl-4alpha-mannobiose
ADP + Polyphosphate <=> AMP + Polyphosphate
1,2-beta-D-Glucan + H2O <=> Sophorose + 1,2-beta-D-Glucan
N4-Acetylcytidine + H2O <=> Cytidine + Acetate
CMP-N-acetylneuraminate + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R <=> CMP + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-R
Neryl diphosphate + Isopentenyl diphosphate <=> Diphosphate + 2-cis,6-cis-Farnesyl diphosphate
2-cis,6-cis-Farnesyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Nerylneryl diphosphate
ATP + Salicylate <=> (Salicyl)adenylate + Diphosphate
(Salicyl)adenylate + CoA <=> AMP + 2-Hydroxybenzoyl-CoA
ATP + Salicylate + CoA <=> AMP + Diphosphate + 2-Hydroxybenzoyl-CoA
D-Xylose + NADP+ <=> D-Xylono-1,4-lactone + NADPH + H+
7,8-Dihydrobiopterin + NADP+ <=> Biopterin + NADPH + H+
Protein-L-arginine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3R)-3-hydroxy-L-arginine + Succinate + CO2
Phosphoenolpyruvate + GTP <=> Enolpyruvoyl-2-diphospho-5'-guanosine + Diphosphate
3-Phospho-D-glycerate + GTP <=> 3-(D-Glyceryl)-diphospho-5'-guanosine + Diphosphate
Enolpyruvoyl-2-diphospho-5'-guanosine + 7,8-Didemethyl-8-hydroxy-5-deazariboflavin <=> GMP + Dehydro coenzyme F420-0
3-(D-Glyceryl)-diphospho-5'-guanosine + 7,8-Didemethyl-8-hydroxy-5-deazariboflavin <=> GMP + 3PG-factor 420-0
L-Isoleucine + 2-Oxoglutarate + Oxygen <=> 3(1)-Hydroxy-L-isoleucine + Succinate + CO2
3(1)-Hydroxy-L-isoleucine + 2-Oxoglutarate + Oxygen <=> (4S)-31,4-Dihydroxy-L-isoleucine + Succinate + CO2
S-Adenosyl-L-methionine + 3-Demethylubiquinol <=> S-Adenosyl-L-homocysteine + Ubiquinol
2-Polyprenyl-6-methoxyphenol + Oxygen <=> 2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + H2O
1-Phospho-alpha-D-galacturonate + H2O <=> D-Galacturonate + Orthophosphate
3-Sulfanylpropanoate + Oxygen <=> 3-Sulfinopropanoate
L-Glutamate + 2-Oxoglutarate + Oxygen <=> (3R)-3-Hydroxy-L-glutamate + Succinate + CO2
beta-D-Mannose <=> beta-D-Glucose
D-Apiose <=> Apulose
S-Adenosyl-L-methionine + (2R)-2-Hydroxy-4-(methylsulfanyl)butanoate <=> S-Adenosyl-L-homocysteine + (2R)-4-(Dimethylsulfaniumyl)-2-hydroxybutanoate
S-Adenosyl-L-methionine + 2-Heptyl-4-hydroxyquinoline-N-oxide <=> S-Adenosyl-L-homocysteine + 2-Heptyl-1-methoxyquinolin-4(1H)-one
Apulose 4-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Xylulose 5-phosphate + Glycerone phosphate
Tuberculosinyl diphosphate + Adenosine <=> 1-Tuberculosinyladenosine + Diphosphate
D-Apionolactone + H2O <=> D-Apionate
Chitobiose + H2O <=> beta-D-Glucosaminyl-(1->4)-N-acetyl-D-glucosamine + Acetate
Neryl diphosphate + H2O <=> Nerol + Diphosphate
3-Oxo-Delta1-steroid + H2O <=> 1-Hydroxy-3-oxo-steroid
Hydroxyheme I <=> Heme A + H2O
3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + Oxygen + H2O <=> 5-[(4-Hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + Ammonia + Hydrogen peroxide
3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + Oxygen <=> 5-[(4-Hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + Hydrogen peroxide
5-[(4-Hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O <=> 5-[(4-Hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + Ammonia
L-Kynurenine + 2-Oxoglutarate <=> 4-Hydroxy-2-quinolinecarboxylic acid + L-Glutamate + H2O
Mercaptopyruvate + [Protein]-L-cysteine <=> Pyruvate + [Protein]-S-sulfanyl-L-cysteine
[Protein]-S-sulfanyl-L-cysteine + Thioredoxin <=> Hydrogen sulfide + [Protein]-L-cysteine + Thioredoxin disulfide
[Glycine cleavage system H]-N6-octanoyl-L-lysine <=> Dihydrolipoylprotein
L-Kynurenine + Glyoxylate <=> 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O
3-Hydroxy-L-kynurenine + Glyoxylate <=> Xanthurenic acid + Glycine + H2O
3-Hydroxy-L-kynurenine + Glyoxylate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + Glycine
ATP + D-Ribulose <=> ADP + D-Ribulose 1-phosphate
D-Ribulose 1-phosphate <=> Glycerone phosphate + Glycolaldehyde
12,18-Didecarboxysiroheme <=> Dihydro-heme d1
sn-Glycerol 1-phosphate + all-trans-Heptaprenyl diphosphate <=> Heptaprenylglyceryl phosphate + Diphosphate
Heptaprenylglyceryl phosphate + H2O <=> Heptaprenylglycerol + Orthophosphate
Allantoate + Orthophosphate <=> (S)-Ureidoglycine + Carbamoyl phosphate
Bacterioruberin <=> Bisanhydrobacterioruberin + 2 H2O
Bacterioruberin <=> Monoanhydrobacterioruberin + H2O
Monoanhydrobacterioruberin <=> Bisanhydrobacterioruberin + H2O
Levoglucosan + NAD+ <=> 3-Dehydrolevoglucosan + NADH + H+
S-Methyl-5-thio-D-ribulose 1-phosphate <=> S-Methyl-1-thio-D-xylulose 5-phosphate
S-Methyl-5-thio-D-ribulose 1-phosphate <=> S-methyl-1-thio-D-ribulose 5-phosphate
Coenzyme F420-0 + FMN <=> Dehydro coenzyme F420-0 + Reduced FMN
ATP + Glycine <=> Diphosphate + Glycyl-AMP
Glycyl-AMP + Peptidyl-carrier protein <=> AMP + Glycyl-[peptidyl-carrier protein]
ATP + Glycine + Peptidyl-carrier protein <=> AMP + Diphosphate + Glycyl-[peptidyl-carrier protein]
C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-L-tyrosine + S-Adenosyl-L-methionine <=> C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + CO2 + 5'-Deoxyadenosine + L-Methionine
ATP + L-Alanine <=> Diphosphate + (L-Alanyl)adenylate
(L-Alanyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Alanyl-[peptidyl-carrier protein]
ATP + L-Alanine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Alanyl-[peptidyl-carrier protein]
ATP + L-Glutamate <=> Diphosphate + (L-Glutamyl)adenylate
(L-Glutamyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Glutamyl-[peptidyl-carrier protein]
ATP + L-Glutamate + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Glutamyl-[peptidyl-carrier protein]
6-Deoxy-6-sulfo-D-fructose + D-Glyceraldehyde 3-phosphate <=> (2S)-3-Sulfolactaldehyde + beta-D-Fructose 6-phosphate
3-Methylbutanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 5-Methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2
2-Methylpropanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 4-Methyl-3-oxopentanoyl-[acyl-carrier-protein] + CoA + CO2
(S)-2-Methylbutanoyl-CoA + Malonyl-[acyl-carrier protein] <=> (4S)-4-Methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2
Lauroyl-CoA + Malonyl-[acyl-carrier protein] <=> 3-Oxotetradecanoyl-[acp] + CoA + CO2
p-Coumaroyl-CoA + 5-Hydroxyanthranilate <=> Avenanthramide A + CoA
Caffeoyl-CoA + 5-Hydroxyanthranilate <=> Avenanthramide C + CoA
ATP + Levoglucosan + H2O <=> ADP + D-Glucose 6-phosphate
GTP + Polyphosphate <=> GDP + Polyphosphate
4-O-Methyl-D-glucopyranuronate ester + H2O <=> 4-O-Methyl-D-glucuronic acid + Alcohol
Cyclic 2,3-bisphospho-D-glycerate + H2O <=> 2,3-Bisphosphoglycerate
S-Methyl-1-thio-D-xylulose 5-phosphate <=> Methanethiol
1'-Hydroxy-gamma-carotene <=> 1'-Hydroxy-1',2'-dihydro-beta,psi-caroten-4'-one
1'-Hydroxy-1',2'-dihydro-beta,psi-caroten-4'-one + S-Adenosyl-L-methionine <=> Thiothece-474 + S-Adenosyl-L-homocysteine
CO2 + Hydrogen <=> Formate
ATP + 1,6-Anhydro-N-acetyl-beta-muramate + H2O <=> ADP + N-Acetylmuramic acid 6-phosphate
Reduced FMN + Oxygen <=> FMN-N5-peroxide
L-Serine <=> Ethanolamine + CO2
L-Tryptophan <=> Indole + Dehydroalanine
L-Tyrosine <=> Phenol + Dehydroalanine
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NAD+
L-Lyxonate <=> 2-Dehydro-3-deoxy-L-arabinonate + H2O
(2S)-2,3-Dihydroxypropane-1-sulfonate <=> 3-Oxopropane-1-sulfonate + H2O
2-Hydroxyethanesulfonate <=> Acetaldehyde + Sulfite
(2S)-2,3-Dihydroxypropane-1-sulfonate <=> Hydroxyacetone + Sulfite
ATP + L-Cysteine <=> Diphosphate + (L-Cysteinyl)adenylate
(L-Cysteinyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Cysteinyl-protein
ATP + L-Cysteine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Cysteinyl-protein
Aceneuramate <=> N-Acetyl-D-mannosamine + Pyruvate
N-Acetyl-alpha-neuraminate <=> Aceneuramate
Aceneuramate <=> N-Acetyl-beta-neuraminate
Fatty acid + Oxygen <=> (2R)-2-Hydroperoxyfatty acid
ATP + L-Threonine <=> Diphosphate + (L-Threonyl)adenylate
(L-Threonyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Threonyl-[L-threonyl-carrier protein]
ATP + L-Threonine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Threonyl-[L-threonyl-carrier protein]
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 2(R)-HPOT
(2,3-Dihydroxybenzoyl)adenylate + Aryl-carrier protein <=> AMP + 2,3-Dihydroxybenzoyl-[aryl-carrier protein]
ATP + 2,3-Dihydroxybenzoate + Aryl-carrier protein <=> AMP + Diphosphate + 2,3-Dihydroxybenzoyl-[aryl-carrier protein]
Alkyl sulfate + 2-Oxoglutarate + Oxygen <=> Aldehyde + Succinate + CO2 + Sulfate
ATP + L-Serine <=> Diphosphate + (L-Seryl)adenylate
(L-Seryl)adenylate + Peptidyl-carrier protein <=> AMP + L-Seryl-[peptidyl-carrier protein]
ATP + L-Serine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Seryl-[peptidyl-carrier protein]
ATP + L-Tryptophan <=> Diphosphate + (L-Tryptophyl)adenylate
(L-Tryptophyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Tryptophyl-[peptidyl-carrier protein]
ATP + L-Tryptophan + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Tryptophyl-[peptidyl-carrier protein]
D-Glyceraldehyde 3-phosphate + Arsenate ion + NAD+ <=> 1-Arsono-3-phospho-D-glycerate + NADH
ATP + dGMP + L-Aspartate <=> ADP + Orthophosphate + N6-Succino-2-amino-2'-deoxyadenylate
Betaine + Co(I) corrinoid protein <=> N,N-Dimethylglycine + Methyl-Co(III) corrinoid protein
ATP + 3-Amino-5-hydroxybenzoate + Acyl-carrier protein <=> 3-Amino-5-hydroxybenzoyl-[acyl-carrier protein] + AMP + Diphosphate
10-Formyltetrahydrofolate + GDP-4-amino-4,6-dideoxy-alpha-D-mannose <=> Tetrahydrofolate + GDP-N-formyl-alpha-D-perosamine
(3R)-3-Hydroxyacyl-CoA + Poly[(R)-3-hydroxyalkanoate]n(n) <=> CoA + Poly[(R)-3-hydroxyalkanoate]n(n+1)
ATP + Apulose <=> ADP + Apulose 4-phosphate
ATP + Fatty acid <=> ADP + Acyl phosphate
3'-Phosphoadenylyl sulfate + omega-Hydroxy-beta-dihydromenaquinone-9 <=> Adenosine 3',5'-bisphosphate + omega-Sulfo-beta-dihydromenaquinone-9
1-Phosphatidyl-D-myo-inositol + H2O <=> 2-Acyl-sn-glycero-3-phospho-1D-myo-inositol + Fatty acid
Phosphatidate + H2O <=> 2-Acyl-sn-glycerol 3-phosphate + Fatty acid
2-Butyloctyl sulfate + H2O <=> 2-Butyloctan-1-ol + Sulfate
2-Hydroxy-3-methyl-fatty-acyl-CoA <=> 2-Methyl-branched fatty aldehyde + Formyl-CoA
(2R)-2-Hydroxy-long-chain fatty acyl-CoA <=> Long-chain fatty aldehyde + Formyl-CoA
C-terminal [Mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + H2O <=> C-terminal [Mycofactocin precursor peptide]-glycine + 3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one
3-Oxoisoapionate 4-phosphate + H2O <=> Glycolate + 3-Phospho-D-glycerate
(3R)-3-Hydroxyacyl-[acyl-carrier protein] + UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine <=> UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + Acyl-carrier protein
(Salicyl)adenylate + Peptidyl-carrier protein <=> AMP + Salicyl-[peptidyl-carrier protein]
ATP + Salicylate + Peptidyl-carrier protein <=> AMP + Diphosphate + Salicyl-[peptidyl-carrier protein]
n CDP-glycerol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n CMP + 4-O-{Poly[(2R)-glycerophospho]-(2R)-glycerophospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
ATP + D-Arabinose <=> ADP + alpha-D-Arabinopyranose 1-phosphate
GTP + alpha-D-Arabinopyranose 1-phosphate <=> Diphosphate + GDP-D-arabinopyranose
3-Epihydroxy-2'-deoxymugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxymugineic acid + Succinate + CO2
Agroclavine + NADPH + H+ + Oxygen <=> Elymoclavine + NADP+ + H2O
Paspalic acid <=> Lysergic acid
Lysergic acid <=> Ergotamine
11-Carbonyl-2beta,20beta-dihydroxycucurbitadienol <=> Cucurbitacin D
11-Carbonyl-2beta,20beta-dihydroxycucurbitadienol <=> Cucurbitacin I
19,25-Dihydroxycucurbitadienol <=> Deacetylcucurbitacin C
Coumarin + NADH + H+ <=> Dihydrocoumarin + NAD+
Osthenol <=> (+)-Columbianetin
Cucurbitacin D + Acetyl-CoA <=> Cucurbitacin B + CoA
Cucurbitacin I + Acetyl-CoA <=> Cucurbitacin E + CoA
S-Adenosyl-L-methionine + Esculetin <=> S-Adenosyl-L-homocysteine + Isoscopoletin
S-Adenosyl-L-methionine + Isoscopoletin <=> S-Adenosyl-L-homocysteine + Scoparone
S-Adenosyl-L-methionine + Esculetin <=> S-Adenosyl-L-homocysteine + Scopoletin
Deacetylcucurbitacin C + Acetyl-CoA <=> Cucurbitacin C + CoA
22,26-Dihydroxycholesterol + 2-Oxoglutarate + Oxygen <=> 16alpha,22,26-Trihydroxycholesterol + Succinate + CO2
Solanidine <=> Solanine
Tomatidine <=> Tomatine
N6-Succino-2-amino-2'-deoxyadenylate <=> dZMP + Fumarate
dZMP + ATP <=> dZDP + ADP
dZDP + ATP <=> dZTP + ADP
S-Adenosyl-L-methionine + 5-Hydroxybenzimidazole <=> S-Adenosyl-L-homocysteine + 5-Methoxybenzimidazole
5-Methoxybenzimidazole <=> 5-Methoxy-6-methylbenzimidazole
5-Methoxy-6-methylbenzimidazole <=> Dimethylbenzimidazole
Bergamottin <=> Epoxybergamottin
Xanthotoxin + NADPH + Oxygen + H+ <=> 5-Hydroxyxanthotoxin + NADP+ + H2O
Scopoletin + NADPH + Oxygen + H+ <=> Fraxetin + NADP+ + H2O
Esculetin + NADPH + Oxygen + H+ <=> 6,7,8-Trihydroxycoumarin + NADP+ + H2O
Caffeoyl-CoA <=> Esculetin
Bergaptol + Geranyl diphosphate <=> Bergamottin + Diphosphate
Bergapten <=> Bergamottin
Epoxybergamottin <=> 6',7'-Dihydroxybergamottin
(2E)-3-(4-Hydroxyphenyl)-2-isocyanoprop-2-enoate <=> Paerucumarin
3-Dehydroshikimate + NADP+ <=> 3,5-Dehydroshikimate + NADPH + H+
3,5-Dehydroshikimate <=> Gallate
Xanthotoxol <=> 5,8-Dihydroxypsoralen
Bergaptol <=> 5,8-Dihydroxypsoralen
5,8-Dihydroxypsoralen <=> 8-Hydroxybergapten
5,8-Dihydroxypsoralen <=> 5-Hydroxyxanthotoxin
Bergapten <=> 8-Hydroxybergapten
8-Hydroxybergapten <=> Isopimpinellin
Psoralen <=> 5,8-Dihydroxypsoralen
(R)-5-Phosphomevalonate <=> trans-Anhydromevalonate phosphate + H2O
trans-Anhydromevalonate phosphate <=> Isopentenyl phosphate + CO2
Dimethylallyl diphosphate + H2O <=> Dimethylallyl phosphate + Orthophosphate
Prenol + ATP <=> Dimethylallyl phosphate + ADP
L-Aspartate + NADPH + H+ + Oxygen <=> N-Hydroxy-L-aspartate + NADP+ + H2O
N-Hydroxy-L-aspartate + NADPH + H+ + Oxygen <=> N,N-Dihydroxy-L-aspartate + NADP+ + H2O
N,N-Dihydroxy-L-aspartate <=> (2S)-2-Nitrosobutanedioate + H2O
(2S)-2-Nitrosobutanedioate + NADPH + H+ + Oxygen <=> (2S)-2-Nitrobutanedioate + NADP+ + H2O
3-Amino-4-hydroxybenzoate + NADPH + H+ + Oxygen <=> 3-Amino-2,4-dihydroxybenzoate + NADP+ + H2O
N5-Hydroxy-L-ornithine <=> (3S)-1,2-Diazinane-3-carboxylate + H2O
(E)-Alk-1-en-1-SO-peroxol <=> (Z)-Alkanethial oxide
1-Methylpyrrolinium + 2 Malonyl-CoA + H2O <=> 4-(1-Methyl-2-pyrrolidinyl)-3-oxobutanoate + 2 CoA + 2 CO2 + H+
Phenyllactate + UDP-glucose <=> Phenyllactylglucose + UDP
(3R)-3-Hydroxyacyl-[acyl-carrier protein] + UDP-N-acetyl-alpha-D-glucosamine <=> Acyl-carrier protein + UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine
N(omega)-Methyl-L-arginine + NADH + H+ + Oxygen <=> N(delta)-Hydroxy-N(omega)-methyl-L-arginine + NAD+ + H2O
N(delta)-Hydroxy-N(omega)-methyl-L-arginine + NADH + H+ + Oxygen <=> N(delta),N'(omega)-Dihydroxy-N(omega)-methyl-L-arginine + NAD+ + H2O
N(delta),N'(omega)-Dihydroxy-N(omega)-methyl-L-arginine + Oxygen <=> N(delta)-Hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + H2O
UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O <=> UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + Acetate
Inulobiose <=> alpha-D-Fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride + H2O
S-Adenosyl-L-methionine + 3-Amino-2,4-dihydroxybenzoate <=> S-Adenosyl-L-homocysteine + 3-Amino-2-hydroxy-4-methoxybenzoate
S-Adenosyl-L-methionine + L-Arginine <=> S-Adenosyl-L-homocysteine + N(omega)-Methyl-L-arginine
L-Carnitine + Co(I) corrinoid protein <=> Methyl-Co(III) corrinoid protein + L-Norcarnitine
(3R)-3-Hydroxyacyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose <=> Acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-{[(3R)-3-hydroxyacyl]amino}-alpha-D-glucopyranose
Acetyl-CoA + 6-Diazo-5-oxo-L-norleucine <=> CoA + N-Acetyl-6-diazo-5-oxo-L-norleucine
7,8-Diaminononanoate + CO2 <=> 8-Amino-7-(carboxyamino)nonanoate
8-Amino-7-(carboxyamino)nonanoate + ATP <=> Dethiobiotin + ADP + Orthophosphate
8-Amino-7-oxononanoate + Protein lysine + CO2 <=> 8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate
UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose + 2-Oxoglutarate <=> UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + L-Glutamate
Chorismate + Ammonia <=> 2-Amino-2-deoxyisochorismate + H2O
2-Amino-2-deoxyisochorismate + Ammonia <=> 4-Amino-4-deoxychorismate + Ammonia
Chorismate + 2 L-Glutamine + H2O <=> 4-Amino-4-deoxychorismate + 2 L-Glutamate + Ammonia
ATP + D-Tagatopyranose 1-phosphate <=> ADP + D-Tagatose 1,6-bisphosphate
R-S-Glutathione + H2O <=> [Gamma-glutamyl-L-cysteine]-S-conjugate + Glycine
N-Methyl carbamate ester + H2O <=> Alcohol + Methylamine + CO2
ATP + 3-Amino-2-hydroxy-4-methoxybenzoate + Nitrite <=> AMP + Diphosphate + Cremeomycin + H2O
S-Methyl-1-thio-D-xylulose 5-phosphate + Glutathione <=> 1-Deoxy-D-xylulose 5-phosphate + S-(Methylsulfanyl)glutathione
(2S)-2-Nitrobutanedioate <=> Fumarate + Nitrite
(8S)-8-Amino-7-oxononanoate + Protein lysine + CO2 <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate
(8S)-8-Amino-7-oxononanoate + Protein lysine + NADPH + H+ <=> [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + H2O + NADP+
[Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + CO2 + H2O + NADP+ <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate + NADPH + H+
(8S)-8-Amino-7-oxononanoate + Protein lysine + NADH + H+ <=> [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + H2O + NAD+
[Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + CO2 + H2O + NAD+ <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate + NADH + H+
Littorine <=> Hyoscyamine aldehyde
UMP + H2O <=> Uracil + D-Ribose 5-phosphate
dTMP + H2O <=> Thymine + 2-Deoxy-D-ribose 1-phosphate
L-Tryptophan <=> 3-(Aminomethyl)indole
2'-Deoxyinosine 5'-phosphate + H2O <=> Deoxyinosine + Orthophosphate
Hypotaurine + NADPH + H+ + Oxygen <=> Taurine + NADP+ + H2O
3'-Phosphoadenylyl sulfate + Lactosylceramide <=> Adenosine 3',5'-bisphosphate + Lactosylceramide sulfate
Lactosylceramide sulfate + H2O <=> Lactosylceramide + Sulfate
UDP-N-acetyl-D-galactosamine + Lactosylceramide sulfate <=> UDP + Gangliotriaosylceramide-II3 sulfate
Gangliotriaosylceramide-II3 sulfate + H2O <=> Lactosylceramide sulfate + N-Acetyl-D-galactosamine
(2R)-2-Hydroxy-4-(methylsulfanyl)butanoate + NAD+ <=> 4-Methylthio-2-oxobutanoic acid + NADH + H+
Benzylmalonyl-CoA + Oxygen <=> (E)-Cinnamoyl-CoA + CO2 + Hydrogen peroxide
Sarcosine + Tetrahydrofolate + Oxygen <=> Glycine + 5,10-Methylenetetrahydrofolate + Hydrogen peroxide
ATP + Indole-3-acetate + CoA <=> AMP + Diphosphate + S-2-(Indol-3-yl)acetyl-CoA
Glucosylceramide + H2O <=> N-Acylsphingosine + beta-D-Glucose
Galactosylceramide + H2O <=> N-Acylsphingosine + beta-D-Galactose
alpha-L-Arabinopyranose + NAD+ <=> L-Arabinono-1,4-lactone + NADH + H+
alpha-L-Arabinopyranose + NADP+ <=> L-Arabinono-1,4-lactone + NADPH + H+
N-Acetyl-D-glucosamine + Oxygen <=> N-Acetyl-D-glucosamino-1,5-lactone + Hydrogen peroxide
N-Acetyl-D-glucosamino-1,5-lactone + H2O <=> N-Acetyl-D-glucosaminate
N-Acetyl-D-galactosamine + Oxygen + H2O <=> N-acetyl-D-galactosaminate + Hydrogen peroxide
N-Acetyl-D-galactosamine + Oxygen <=> N-Acetyl-D-galactosamino-1,5-lactone + Hydrogen peroxide
N-Acetyl-D-galactosamino-1,5-lactone + H2O <=> N-acetyl-D-galactosaminate
Acetyl-CoA + N-Terminal-L-methionyl-[tubulin] <=> N-Terminal-Nalpha-acetyl-L-methionyl-[tubulin] + CoA
beta-D-Glucosyl-(1->4)-D-galactose + Orthophosphate <=> D-Glucose 1-phosphate + D-Galactose
ATP + NAD+ <=> ADP + 3'-NADP+
Phenylsuccinate + Succinyl-CoA <=> 2-Phenylsuccinyl-CoA + Succinate
Phenylsuccinate + Succinyl-CoA <=> 3-Phenylsuccinyl-CoA + Succinate
2-alpha-D-Glucosyl-D-glucose + H2O <=> beta-D-Glucose + D-Glucose
2 alpha-Isomaltosyl-(1->4)-maltotriose <=> alpha-Isomaltosyl-(1->3)-alpha-isomaltosyl-(1->4)-maltotriose + Maltotriose
alpha-Isomaltosyl-(1->3)-alpha-isomaltosyl-(1->4)-maltotriose <=> Cyclobis-1,6-alpha-nigerosyl + Maltotriose
alpha-D-Xylose <=> alpha-D-Xylulofuranose
Adenine + NAD+ + H2O <=> 8-Hydroxyadenine + NADH + H+
8-Hydroxyadenine + NAD+ + H2O <=> 2,8-Dihydroxyadenine + NADH + H+
Adenine + H2O + Oxygen <=> 8-Hydroxyadenine + Hydrogen peroxide
8-Hydroxyadenine + H2O + Oxygen <=> 2,8-Dihydroxyadenine + Hydrogen peroxide
beta-L-Arabinopyranose <=> L-Ribulose
8-[(1R,2R)-3-Oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate + NADP+ <=> (9R,13R)-12-Oxo-phytodienoic acid + NADPH + H+
2 p-Coumaroylagmatine <=> Hordatine A
2 Feruloylagmatine <=> Hordatine B
UDP-glucose + Protopanaxatriol <=> UDP + Ginsenoside F1
6-Sulfo-beta-D-quinovose <=> 6-Sulfo-D-rhamnose
D-Glucose + NADP+ <=> 6-Dehydro-D-glucose + NADPH + H+
UTP <=> 3',5'-Cyclic UMP + Diphosphate
Methyl-Co(III) corrinoid protein + 5,6,7,8-Tetrahydromethanopterin <=> 5-Methyl-5,6,7,8-tetrahydromethanopterin + Co(I) corrinoid protein
6-Deoxy-6-sulfo-D-fructose + D-Glyceraldehyde 3-phosphate <=> D-Xylulose 5-phosphate + 4-Deoxy-4-sulfo-D-erythrose
4-Deoxy-4-sulfo-D-erythrulose + D-Glyceraldehyde 3-phosphate <=> D-Xylulose 5-phosphate + Sulfoacetaldehyde
Solabiose + Orthophosphate <=> D-Galactose + D-Glucose 1-phosphate
all-trans-Pentaprenyl diphosphate + sn-Glycerol 1-phosphate <=> sn-3-O-(Farnesylgeranyl)glycerol 1-phosphate + Diphosphate
all-trans-Pentaprenyl diphosphate + sn-3-O-(Farnesylgeranyl)glycerol 1-phosphate <=> 2,3-Bis-O-(geranylfarnesyl)-sn-glycerol 1-phosphate + Diphosphate
4-Deoxy-4-sulfo-D-erythrose <=> 4-Deoxy-4-sulfo-D-erythrulose
2-Hydroxyethanesulfonate + NAD+ <=> Sulfoacetaldehyde + NADH + H+
D-Glucoside + Ferricytochrome c <=> 3-Dehydro-D-glucoside + Ferrocytochrome c
2-Oxoadipate + Oxygen <=> (R)-2-Hydroxyglutarate + CO2
(3R)-3-[(Carboxylmethyl)amino]fatty acid + 2-Oxoglutarate + Oxygen <=> (3R)-3-{[Carboxy(hydroxy)methyl]amino}fatty acid + Succinate + CO2
(3R)-3-{[Carboxy(hydroxy)methyl]amino}fatty acid + 2-Oxoglutarate + Oxygen <=> (3R)-3-Isocyanyl-fatty acid + Succinate + 2 CO2 + 2 H2O
(3R)-3-[(Carboxylmethyl)amino]fatty acid + 2 2-Oxoglutarate + 2 Oxygen <=> (3R)-3-Isocyanyl-fatty acid + 2 Succinate + 3 CO2 + 2 H2O
Protein histidine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3S)-3-hydroxy-L-histidine + Succinate + CO2
Betaine + NADH + H+ + Oxygen <=> N,N-Dimethylglycine + NAD+ + Formaldehyde + H2O
Sulfoquinovose + Reduced FMN + Oxygen <=> 6-Dehydro-D-glucose + FMN + Sulfite + H2O
Secondary-alkyl amine + NAD+ + H2O <=> Ketone + NADH + Ammonia + H+
Secondary-alkyl amine + NADP+ + H2O <=> Ketone + NADPH + Ammonia + H+
Iminoaspartate + H2O <=> Oxaloacetate + Ammonia
N-(1-Deoxy-D-fructos-1-yl)amine + Oxygen <=> 2-[(3S,4R,5R)-3,4,5,6-Tetrahydroxy-2-oxohexylidene]amine + Hydrogen peroxide
2-[(3S,4R,5R)-3,4,5,6-Tetrahydroxy-2-oxohexylidene]amine + H2O <=> D-Glucosone + Amine
N-(1-Deoxy-D-fructos-1-yl)amine + Oxygen + H2O <=> D-Glucosone + Amine + Hydrogen peroxide
N-(1-Deoxy-D-fructos-1-yl)amine + Oxygen + H2O <=> (1-Deoxy-D-fructos-1-yl)amine + Aldehyde + Hydrogen peroxide
Sulfoacetate + CoA + ATP <=> Sulfoacetyl-CoA + AMP + Diphosphate
L-Tyrosine + NADPH + Oxygen + H+ <=> 3,4-Dihydroxy-L-phenylalanine + NADP+ + H2O
3,4-Dihydroxy-L-phenylalanine + NADPH + Oxygen + H+ <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + NADP+ + 2 H2O
Carminate + Oxygen <=> 3'-Dehydrocarminate + Hydrogen peroxide
D-Lysine <=> 6-Amino-2-oxohexanoate
Glutarate + Succinyl-CoA <=> Glutaryl-CoA + Succinate
(R)-2-Hydroxyglutarate <=> 2-Oxoglutarate
L-2-Aminoadipate 6-semialdehyde <=> L-2-Aminoadipate
(3R)-3-[(Carboxylmethyl)amino]fatty acid + Acyl-carrier protein <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + Glycine + H2O
Androstan-3alpha,17beta-diol + NAD+ <=> Androsterone + NADH + H+
5(S)-HETE + NADP+ <=> 5-OxoETE + NADPH + H+
11alpha-Hydroxy-9,15-dioxoprostanoate + NAD+ <=> (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADH + H+
11alpha-Hydroxy-9,15-dioxoprostanoate + NADP+ <=> (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+
2 Glutathione + 12(S)-HPETE <=> Glutathione disulfide + 12(S)-HETE + H2O
12(R)-HPETE <=> 12-OxoETE + H2O
12(S)-HPETE <=> 12-OxoETE + H2O
Poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl] + H2O <=> Heparosan D-glucuronate + Acetate
3'-Phosphoadenylyl sulfate + Heparosan D-glucuronate <=> Adenosine 3',5'-bisphosphate + Heparosan-N-sulfate D-glucuronate
3'-Phosphoadenylyl sulfate + Heparan sulfate containing L-iduronate 2-sulfate <=> Adenosine 3',5'-bisphosphate + 3-O-Sulfated heparan sulfate containing L-iduronate 2-sulfate
Daidzin + H2O <=> Daidzein + beta-D-Glucose
Genistin + H2O <=> Genistein + beta-D-Glucose
Puerarin <=> Daidzein + 1,5-Anhydro-D-erythro-hex-1-en-3-ulose
Daidzein + NADPH + H+ <=> (R)-Dihydrodaidzein + NADP+
(R)-Dihydrodaidzein <=> (S)-Dihydrodaidzein
(S)-Dihydrodaidzein + NADPH + H+ <=> (3S,4R)-Tetrahydrodaidzein + NADP+
(3S,4R)-Tetrahydrodaidzein <=> Equol
(R)-Dihydrodaidzein <=> O-Desmethylangolensin
Genistein <=> Dihydrogenistein
Dihydrogenistein <=> 6'-Hydroxy-O-desmethylangolensin
Rutin + H2O <=> Isoquercitrin + beta-L-Rhamnose
Naringin + H2O <=> Naringenin 7-O-beta-D-glucoside + beta-L-Rhamnose
Isoquercitrin + H2O <=> Quercetin + beta-D-Glucose
Apigenin <=> Naringenin
Quercetin <=> Taxifolin
Kaempferol <=> Dihydrokaempferol
Luteolin <=> Eriodictyol
Taxifolin + NADH + H+ <=> 2-Hydroxy-1-(2,4,6-trihydroxyphenyl)-3-(3,4-dihydroxyphenyl)propan-1-one + NAD+
Dihydrokaempferol + NADH + H+ <=> 2-Hydroxy-1-(2,4,6-trihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one + NAD+
Eriodictyol + NADH + H+ <=> 3-Hydroxyphloretin + NAD+
Naringenin + NADH + H+ <=> Phloretin + NAD+
Naringenin <=> 5,7,8-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
5,7,8-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one <=> (2E,4E)-2,4-Dihydroxy-4-[6-(4-hydroxyphenyl)-2,4-dioxodihydro-2H-pyran-3(4H)-ylidene]but-2-enoate
(2E,4E)-2,4-Dihydroxy-4-[6-(4-hydroxyphenyl)-2,4-dioxodihydro-2H-pyran-3(4H)-ylidene]but-2-enoate + H2O <=> 5-(4-Hydroxyphenyl)-3-oxovalero-delta-lactone + Oxaloacetate
5-(4-Hydroxyphenyl)-3-oxovalero-delta-lactone + H2O <=> 5-Hydroxy-5-(4-hydroxyphenyl)-3-oxopentanoate
5-Hydroxy-5-(4-hydroxyphenyl)-3-oxopentanoate <=> 4-Hydroxy-4-(4-hydroxyphenyl)-butan-2-one + CO2
4-Hydroxy-4-(4-hydroxyphenyl)-butan-2-one <=> 4-Hydroxycinnamoylmethane + H2O
Adenine in double-stranded RNA + H2O <=> Hypoxanthine in double-stranded RNA + Ammonia
Naringenin 7-O-beta-D-glucoside + H2O <=> Naringenin + beta-D-Glucose
3-Hydroxyphloretin + H2O <=> 3,4-Dihydroxyphenylpropanoate + Phloroglucinol
Taxifolin <=> Alphitonin
Dihydrokaempferol <=> Maesopsin
Alphitonin + 2 H2O <=> 3,4-Dihydroxyphenylacetate + Phloroglucinol + CO2 + 2 H+
Maesopsin <=> 4-Hydroxyphenylacetate + Phloroglucinol
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose <=> UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-galactose
UDP-N-acetyl-D-galactosaminuronic acid <=> UDP-2-acetamido-2-deoxy-L-altruronic acid
alpha-D-Ribose 1-phosphate + ATP <=> D-Ribose 1,5-bisphosphate + ADP
D-Ribulose 1,5-bisphosphate + H2O <=> D-Ribulose 1-phosphate + Orthophosphate
(-)-5-Oxo-1,2-campholide <=> [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetate
(-)-3-exo-Hydroxycamphor + NAD+ <=> (-)-Bornane-2,5-dione + NADH + H+
(+)-6-endo-Hydroxycamphor <=> Bornane-2,6-dione
(+)-6-exo-Hydroxycamphor <=> Bornane-2,6-dione
D-Glutamate + Acetyl-CoA <=> N-Acetyl-D-glutamate + CoA
N-Acetyl-D-glutamate <=> N-Acetyl-L-glutamate
N-Acetyl-L-glutamate <=> L-Glutamate
Geranylgeranyl diphosphate <=> (-)-Cyatha-3,12-diene + Diphosphate
Geranylgeranyl diphosphate + H2O <=> Neoverrucosan-5beta-ol + Diphosphate
Geranylgeranyl diphosphate + H2O <=> Verrucosan-2beta-ol + Diphosphate
Geranylgeranyl diphosphate <=> (R)-Axinyssene + Diphosphate
Geranylgeranyl diphosphate <=> Lydicene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-exo-beta-Bergamotene + Diphosphate
beta-L-Fucopyranose + NADP+ <=> L-Fucono-1,5-lactone + NADPH + H+
Fumagillol + NADP+ <=> 5-Dehydrofumagillol + NADPH + H+
S-Adenosyl-L-methionine <=> L-Homoserine lactone + 5'-Methylthioadenosine
5-Hydroxymethylcytosine in DNA + 2-Oxoglutarate + Oxygen <=> 5-Formylcytosine in DNA + Succinate + CO2 + H2O
5-Formylcytosine in DNA + 2-Oxoglutarate + Oxygen <=> 5-Carboxycytosine in DNA + Succinate + CO2
Cyclopeptine + 2-Oxoglutarate + Oxygen <=> Dehydrocyclopeptine + Succinate + CO2 + H2O
Dehydrocyclopeptine + 2-Oxoglutarate + Oxygen <=> (-)-Cyclopenine + Succinate + CO2
Canavanine <=> Vinylglycine + N-Hydroxyguanidine
Vinylglycine <=> (2E)-2-Aminobut-2-enoate
(2E)-2-Aminobut-2-enoate + H2O <=> L-Homoserine
Canavanine + H2O <=> L-Homoserine + N-Hydroxyguanidine
L-Mimosine <=> 3-Hydroxy-4H-pyrid-4-one + Dehydroalanine
(5R)-Hydroxy-(+)-exo-beta-bergamotene + Oxygen <=> (3S)-3-[2-Methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + H2O
N-(Sulfonatooxy)alkanimidothioate <=> Nitrile + Sulfate + Sulfur
5-Dehydro-6-demethoxyfumagillol + 2-Oxoglutarate + Oxygen <=> 5-Dehydro-6-demethoxy-6-hydroxyfumagillol + Succinate + CO2
S-Adenosyl-L-methionine + 5-Dehydro-6-demethoxy-6-hydroxyfumagillol <=> S-Adenosyl-L-homocysteine + 5-Dehydrofumagillol
1,2-beta-D-Glucan + D-Glucoside <=> 1,2-beta-D-Glucan + beta-D-Glucosyl-(1->2)-D-glucoside
3-O-beta-D-Glucosyl-beta-D-glucuronoside + Orthophosphate <=> beta-D-Glucuronoside + D-Glucose 1-phosphate
Palatinose + H2O <=> alpha-D-Glucose + D-Fructose
Isopentenyl diphosphate + H2O <=> Isopentenyl phosphate + Orthophosphate
3-Ketosucrose + H2O <=> 3-Dehydro-D-glucopyranose + beta-D-Fructose
N-(Sulfonatooxy)alkenimidothioic acid <=> Epithionitrile + Sulfate
Phenyl-N-(sulfonatooxy)methanimidothioate <=> Benzyl thiocyanate + Sulfate
N-(Sulfonatooxy)prop-2-enimidothioate <=> Prop-2-enylthiocyanate + Sulfate
N-(Sulfonatooxy)prop-2-enimidothioate <=> 2-(Thiiran-2-yl)acetonitrile + Sulfate
Propanoate + NAD+ <=> Acrylic acid + NADH + H+
sym-Homospermidine + Oxygen + H+ <=> N-(4-Aminobutylpyrrolinium) ion + Hydrogen peroxide + Ammonia
N-(4-Aminobutylpyrrolinium) ion + Oxygen + H2O <=> N-(4-Oxobutylpyrrolinium) ion + Ammonia + Hydrogen peroxide
N-(4-Oxobutylpyrrolinium) ion <=> 1-Formylpyrrolizidine + H+
sym-Homospermidine + 2 Oxygen + H2O <=> 1-Formylpyrrolizidine + 2 Hydrogen peroxide + 2 Ammonia
2,6-Dichloro-p-benzoquinone + H2O <=> 2-Chloro-6-hydroxy-1,4-benzoquinone + Cl-
2,4,6-Trichlorophenol + FADH2 + Oxygen <=> 2-Chloro-6-hydroxy-1,4-benzoquinone + 2 Cl- + FAD
L-Fucose <=> beta-L-Fucopyranose
Fumagillol + Dodecapentaenoyl-[acyl-carrier protein] <=> Prefumagillin + Acyl-carrier protein
Prefumagillin <=> Fumagillin
L-Glutamate 5-semialdehyde + NADP+ + H2O <=> L-Glutamate + NADPH + H+
Oleanolic acid <=> Echinocystic acid
Echinocystic acid <=> Quillaic acid
Quillaic acid <=> Quillaic acid 3-O-beta-D-glucuronide
Quillaic acid 3-O-beta-D-glucuronide + UDP-alpha-D-galactose <=> Quillaic acid 3-O-beta-D-galactosyl-1,2-beta-D-glucuronide + UDP
Quillaic acid 3-O-beta-D-galactosyl-1,2-beta-D-glucuronide + UDP-D-xylose <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide + UDP
Quillaic acid 3-O-beta-D-galactosyl-1,2-beta-D-glucuronide + UDP-L-rhamnose <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide + UDP
Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside
Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside
Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside + UDP-L-rhamnose <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP
Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside + UDP-L-rhamnose <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP
Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP-D-xylose <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP
Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP-D-xylose <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP
Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide 28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-(beta-D-glucosyl-1,3)-alpha-L-rhamnosyl-1,2-(alpha-L-rhamnosyl-1,3)-4-O-acetyl-beta-D-fucoside
2-Oxoadipate + Thiamin diphosphate <=> 4-Carboxy-1-hydroxybutyryl-ThPP + CO2
4-Carboxy-1-hydroxybutyryl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine + Thiamin diphosphate
r1p_c <-> r1p_h
r5p_e <-> r5p_p
r5p_c <-> r5p_h
h_e + raffin_e <-> h_c + raffin_c
raffin_e <-> raffin_p
retn_c <-> retn_n
rbl__L_c <-> rbl__L_x
rb15bp_c <-> rb15bp_x
rbt_c <-> rbt_e
retinal_c <-> retinal_e
retinal_h <-> retinal_s
retn_c <-> retn_e
retn_c <-> retn_r
retinol_e <-> retinol_c
h_p + rfamp_p <-> h_c + rfamp_e
bhb_p <-> bhb_e
bhb_p <-> bhb_c
h_e + ribflv_e <-> h_c + ribflv_c
rib__D_e <-> rib__D_c
h_e + rib__D_e <-> h_c + rib__D_c
rib__D_e <-> rib__D_p
rmn_e <-> rmn_c
Rtotal2crn_c <-> Rtotal2crn_m
Rtotal3crn_c <-> Rtotal3crn_m
Rtotalcrn_c <-> Rtotalcrn_m
ru5p__L_c <-> ru5p__L_x
h_e + rbt_e <-> rbt_c + h_c
Rtotal_c <-> Rtotal_r
Rtotal_c <-> Rtotal_g
pi_h + ru5p__D_c <-> pi_c + ru5p__D_h
saccrp__L_c <-> saccrp__L_m
saccrp__L_c <-> saccrp__L_e
salcn_e <-> salcn_p
salc_e <-> salc_c
salcn_p <-> salcn_c
sarcs_e <-> sarcs_c
sarcs_c <-> sarcs_m
sarcs_c <-> sarcs_x
sbt__D_e <-> sbt__D_c
sbt__L_e <-> sbt__L_c
h_e + sbt__D_e <-> h_c + sbt__D_c
sbt__D_e <-> sbt__D_p
seasmet_c <-> seasmet_n
selmeth_e <-> selmeth_c
na1_e + selmeth_e <-> na1_c + selmeth_c
ser__L_e + na1_e + ala__L_c <-> ser__L_c + na1_c + ala__L_e
asn__L_c + ser__L_e + na1_e <-> ser__L_c + asn__L_e + na1_c
cl_e + 2.0 na1_e + ser__L_e <-> cl_c + 2.0 na1_c + ser__L_c
na1_e + ser__L_e + cl_e <-> na1_c + ser__L_c + cl_c
cys__L_c + ser__L_e + na1_e <-> ser__L_c + na1_c + cys__L_e
gln__L_c + ser__D_e <-> gln__L_e + ser__D_c
gly_c + ser__D_e <-> gly_e + ser__D_c
ser__L_e + gln__L_c + na1_e <-> ser__L_c + na1_c + gln__L_e
gln__L_c + ser__L_e <-> ser__L_c + gln__L_e
gly_c + ser__L_e <-> ser__L_c + gly_e
lys__L_c + na1_e + ser__L_e <-> ser__L_c + lys__L_e + na1_c
ser__L_e + thr__L_c + na1_e <-> ser__L_c + na1_c + thr__L_e
ser__L_e + 2.0 na1_e + h_c <-> ser__L_c + h_e + 2.0 na1_c
ser__L_c <-> ser__L_h
ser__L_c <-> ser__L_p
slfcys_c <-> slfcys_e
h_p + sheme_e <-> h_c + sheme_p
skm_e <-> skm_p
sl__L_c <-> sl__L_e
2.0 hco3_c + so4_e <-> so4_c + 2.0 hco3_e
oxa_c + 2.0 so4_e <-> 2.0 so4_c + oxa_e
spc_cho_c <-> spc_cho_e
sphgn_e <-> sphgn_c
sphgn_c <-> sphgn_g
sphgn_c <-> sphgn_n
sphgn_r <-> sphgn_c
h_e + spmd_e <-> h_c + spmd_c
h_p + spmd_p <-> h_c + spmd_c
h_c + spmd_c <-> h_m + spmd_m
h_c + sprm_e <-> sprm_c + h_e
sprm_e <-> sprm_c
Ssq23epx_r <-> Ssq23epx_c
sql_c <-> sql_e
sql_c <-> sql_r
srb__L_e <-> srb__L_c
h_e + srtn_e <-> h_c + srtn_c
srtn_e + 2.0 na1_e + 2.0 k_c <-> 2.0 na1_c + 2.0 k_e + srtn_c
srtn_e <-> srtn_c
stcoa_c <-> stcoa_x
subeac_x <-> subeac_c
subeac_c <-> subeac_e
sucbz_h <-> sucbz_x
succ_e <-> succ_c
succ_p <-> succ_c
3.0 h_e + succ_e <-> 3.0 h_c + succ_c
3.0 h_p + succ_p <-> 3.0 h_c + succ_c
h_e + succ_e <-> h_c + succ_c
h_e + succ_c <-> h_c + succ_e
succ_c + h_p <-> h_c + succ_p
succ_e + 2.0 na1_e <-> succ_c + 2.0 na1_c
succ_e + 3.0 na1_e <-> succ_c + 3.0 na1_c
succ_e <-> succ_p
succ_c + pi_m <-> pi_c + succ_m
succ_m <-> succ_c
succ_c <-> succ_x
h_p + succ_p <-> h_c + succ_c
mal__L_c + succ_e <-> mal__L_e + succ_c
h_e + sucr_e <-> h_c + sucr_c
sucr_e <-> sucr_p
sucsal_c <-> sucsal_e
sucsal_m <-> sucsal_c
sucr_p <-> sucr_c
sulfac_e <-> sulfac_p
T4hcinnm_c + oh1_e <-> oh1_c + T4hcinnm_e
T4hcinnm_e <-> T4hcinnm_p
T4hcinnm_m <-> T4hcinnm_c
T4hcinnm_p <-> T4hcinnm_c
tag__D_e <-> tag__D_c
tag__D_e <-> tag__D_p
tartr__D_e <-> tartr__D_c
tartr__L_e <-> tartr__L_c
tartr__L_e <-> tartr__L_p
tartr__L_p <-> tartr__L_c
3.0 h_p + tartr__D_p <-> 3.0 h_c + tartr__D_c
cl_e + 2.0 na1_e + taur_e <-> cl_c + 2.0 na1_c + taur_c
h_e + taur_e <-> h_c + taur_c
taur_c <-> taur_e
taur_e + 2.0 na1_e <-> taur_c + 2.0 na1_c
taur_c + na1_c <-> taur_x + na1_x
cl_c + 2.0 na1_c + taur_c <-> cl_x + 2.0 na1_x + taur_x
taur_e <-> taur_p
taxol_e <-> taxol_c
tcb_e <-> tcb_p
h_p + tcb_p <-> h_c + tcb_c
hco3_c + tchola_e <-> hco3_e + tchola_c
tchola_e + 2.0 na1_e <-> tchola_c + 2.0 na1_c
tchola_e <-> tchola_c
tchola_x <-> tchola_c
tcynt_c <-> tcynt_e
tcynt_e <-> tcynt_p
tcynt_m <-> tcynt_c
tcynt_p <-> tcynt_c
tdchola_e <-> tdchola_c
tdchola_x <-> tdchola_c
ttdcrn_c <-> ttdcrn_e
tega_e <-> tega_c
tgua_e <-> tgua_c
thbpt_c <-> thbpt_e
thbpt_c <-> thbpt_m
oh1_c + thf_e <-> thf_c + oh1_e
h2o_c + thf_e <-> h2o_e + thf_c
thf_c <-> thf_l
thf_c <-> thf_m
h_c + thf_c <-> h_m + thf_m
na1_e + thymd_e <-> na1_c + thymd_c
2.0 na1_e + thymd_e <-> 2.0 na1_c + thymd_c
thymd_e <-> thymd_p
oh1_c + thmmp_e <-> thmmp_c + oh1_e
h2o_c + thmmp_e <-> h2o_e + thmmp_c
thmmp_c + oh1_m <-> oh1_c + thmmp_m
h2o_m + thmmp_c <-> h2o_c + thmmp_m
thmmp_e <-> thmmp_c
thmtp_c <-> thmtp_h
thmpp_c <-> thmpp_m
thmpp_c <-> thmpp_h
2.0 oh1_m + thmpp_c <-> thmpp_m + 2.0 oh1_c
2.0 h2o_m + thmpp_c <-> 2.0 h2o_c + thmpp_m
thmtp_c + 3.0 oh1_e <-> 3.0 oh1_c + thmtp_e
3.0 h2o_e + thmtp_c <-> 3.0 h2o_c + thmtp_e
h_e + thym_e <-> h_c + thym_c
thp2c_c <-> thp2c_x
thr__L_e + na1_e + ala__L_c <-> ala__L_e + na1_c + thr__L_c
asn__L_c + na1_e + thr__L_e <-> asn__L_e + na1_c + thr__L_c
cl_e + 2.0 na1_e + thr__L_e <-> cl_c + 2.0 na1_c + thr__L_c
na1_e + thr__L_e + cys__L_c <-> cys__L_e + na1_c + thr__L_c
gln__L_c + na1_e + thr__L_e <-> thr__L_c + na1_c + gln__L_e
gln__L_c + thr__L_e <-> gln__L_e + thr__L_c
gly_c + thr__L_e <-> gly_e + thr__L_c
na1_c + thr__L_c <-> na1_h + thr__L_h
na1_c + thr__L_c <-> na1_m + thr__L_m
phe__L_c + thr__L_e <-> phe__L_e + thr__L_c
thrp_e <-> thrp_p
ser__L_c + na1_e + thr__L_e <-> ser__L_e + na1_c + thr__L_c
na1_e + thr__L_e <-> na1_c + thr__L_c
na1_p + thr__L_p <-> na1_c + thr__L_c
thymd_e <-> thymd_c
thymd_l <-> thymd_c
thymd_c <-> thymd_m
thym_e <-> thym_c
thym_c + h_p <-> h_c + thym_p
thym_c + h_e <-> h_c + thym_e
h_p + thym_p <-> h_c + thym_c
thym_e <-> thym_p
tmao_e <-> tmao_p
h_e + tma_e <-> tma_c + h_c
tma_e <-> tma_p
tmlys_c <-> tmlys_e
tmlys_r <-> tmlys_c
tmlys_c <-> tmlys_m
tolbutamide_e <-> tolbutamide_c
h_p + tol_p <-> h_c + tol_c
h_p + tol_c <-> h_c + tol_e
h_p + tol_p <-> h_c + tol_e
h_p + tol_c <-> h_c + tol_p
tol_e <-> tol_p
tol_p <-> tol_c
g3p_c + pi_m <-> g3p_m + pi_c
trdox_c <-> trdox_x
trdrd_c <-> trdrd_x
tre6p_e <-> tre6p_c
tre_e <-> tre_c
h_e + tre_e <-> h_c + tre_c
h_c + tre_c <-> h_v + tre_v
cl_e + 2.0 na1_e + trp__L_e <-> cl_c + 2.0 na1_c + trp__L_c
na1_e + cl_e + trp__L_e <-> na1_c + cl_c + trp__L_c
trp__L_e <-> trp__L_c
trp__L_e + na1_e <-> trp__L_c + na1_c
trp__L_e <-> trp__L_p
trp__L_c <-> trp__L_p
h_c + trypta_c <-> h_e + trypta_e
na1_c + ttdcrn_c <-> na1_e + ttdcrn_e
ttdcrn_c <-> ttdcrn_m
h_p + ttrcyc_p <-> h_c + ttrcyc_c
h_p + ttrcyc_c <-> h_c + ttrcyc_e
h_p + ttrcyc_c <-> h_c + ttrcyc_p
h_e + ttrcyc_c <-> h_c + ttrcyc_e
h_p + ttrcyc_p <-> h_c + ttrcyc_e
txa2_e <-> txa2_c
txa2_c <-> txa2_r
tym_c <-> tym_e
h_c + tym_c <-> h_e + tym_e
tym_e <-> tym_p
cl_e + 2.0 na1_e + tyr__L_e <-> cl_c + 2.0 na1_c + tyr__L_c
na1_e + cl_e + tyr__L_e <-> na1_c + cl_c + tyr__L_c
phe__L_c + tyr__L_e <-> phe__L_e + tyr__L_c
tyrp_e <-> tyrp_p
tyr__L_e <-> tyr__L_c
tyr__L_e + na1_e <-> tyr__L_c + na1_c
tyr__L_c + h_v <-> h_c + tyr__L_v
tyr__L_e <-> tyr__L_p
tyr__L_c <-> tyr__L_p
uacgam_e <-> uacgam_p
hco3_c + HC02194_e <-> hco3_e + HC02194_c
2.0 na1_e + HC02194_e <-> 2.0 na1_c + HC02194_c
udcpp_e <-> udcpp_c
udcpp_p <-> udcpp_c
udcpp_w <-> udcpp_c
udpacgal_e <-> udpacgal_p
udpacgal_c <-> udpacgal_l
udparab_c <-> udparab_g
udpgal_c <-> udpgal_g
udpgal_c <-> udpgal_n
udpgal_c <-> udpgal_r
udpgal_e <-> udpgal_p
ump_g + udpgal_c <-> ump_c + udpgal_g
udpgal_c <-> udpgal_x
udpgal_c + ump_h <-> udpgal_h + ump_c
udpglcur_r + ump_c <-> udpglcur_c + ump_r
udpglcur_g + ump_c <-> udpglcur_c + ump_g
udpglcur_e <-> udpglcur_p
udpglcur_e <-> udpglcur_c
udpg_c + ump_r <-> udpg_r + ump_c
udpg_c + ump_g <-> udpg_g + ump_c
udpg_e <-> udpg_p
udpg_c <-> udpg_x
udp_h + udpg_c <-> udp_c + udpg_h
udpsq_h <-> udpsq_c
ump_r + udpxyl_c <-> ump_c + udpxyl_r
ump_g + udpxyl_c <-> ump_c + udpxyl_g
udp_h <-> udp_c
udp_c <-> udp_l
udp_c <-> udp_m
udp_c <-> udp_n
ump_r + udpacgal_c <-> ump_c + udpacgal_r
ump_g + udpacgal_c <-> ump_c + udpacgal_g
ump_g + uacgam_c <-> ump_c + uacgam_g
4hbz_p + h_p <-> 4hbz_c + h_c
h_e + ump_e <-> h_c + ump_c
uppg3_h <-> uppg3_c
urate_c <-> urate_e
h_e + urate_e <-> h_c + urate_c
urate_e <-> urate_p
h_c + urate_c <-> h_m + urate_m
urate_p + h_p <-> urate_c + h_c
urate_x <-> urate_c
ura_c <-> ura_p
urcan_c <-> urcan_e
2.0 h_e + urea_e <-> 2.0 h_c + urea_c
2.0 h_p + urea_p <-> 2.0 h_c + urea_c
na1_e + urea_e <-> na1_c + urea_c
h_e + urea_e <-> h_c + urea_c
na1_c + urea_c <-> na1_m + urea_m
uri_e <-> uri_c
na1_e + uri_e <-> na1_c + uri_c
uri_e + 2.0 na1_e <-> uri_c + 2.0 na1_c
uri_e <-> uri_p
utp_c <-> utp_h
2.0 h_c + utp_c + ump_m <-> ump_c + 2.0 h_m + utp_m
utp_c <-> utp_m
utp_c <-> utp_n
uri_l <-> uri_c
uri_c <-> uri_m
uri_c <-> uri_n
cl_e + 2.0 na1_e + val__L_e <-> cl_c + 2.0 na1_c + val__L_c
na1_e + cl_e + val__L_e <-> na1_c + cl_c + val__L_c
leu__L_c + val__L_e <-> leu__L_e + val__L_c
phe__L_c + val__L_e <-> phe__L_e + val__L_c
h_c + val__L_c <-> h_m + val__L_m
h_e + val__L_e <-> h_c + val__L_c
h_p + val__L_p <-> h_c + val__L_c
h_p + val__L_c <-> val__L_p + h_c
na1_h + val__L_h <-> na1_c + val__L_c
na1_m + val__L_m <-> na1_c + val__L_c
h_c + val__L_c <-> h_h + val__L_h
h_p + vanlt_p <-> h_c + vanlt_c
vanln_e <-> vanln_p
vanlt_e <-> vanlt_p
phllqne_c <-> phllqne_e
h_p + vanln_p <-> vanln_c + h_c
xan_e <-> xan_c
ura_e + xan_e <-> ura_c + xan_c
xan_e <-> xan_p
xan_p <-> xan_c
xan_c <-> xan_x
xmp_e <-> xmp_p
xmp_e <-> xmp_c
xol25oh_c <-> xol25oh_e
xol25oh_r <-> xol25oh_c
xtsn_e <-> xtsn_p
xtsn_e <-> xtsn_c
xylt_e <-> xylt_c
xylu__D_c <-> xylu__D_e
xylu__L_c <-> xylu__L_e
h_p + xylu__L_p <-> h_c + xylu__L_c
xylu__L_e <-> xylu__L_p
xyl__D_e <-> xyl__D_c
xyl__D_e <-> xyl__D_p
xyl__D_l <-> xyl__D_c
pi_h + xu5p__D_c <-> pi_c + xu5p__D_h
gtocophe_e <-> gtocophe_c
zymst_e <-> zymst_c
dxyl5p_c <-> dxyl5p_h
orot_c <-> orot_m
pac_c <-> pac_e
q10h2_m <-> q10h2_c
q10_c <-> q10_m
gdp_m + gtp_c <-> gdp_c + gtp_m
adn_c + ins_e <-> adn_e + ins_c
amp_x + atp_c <-> amp_c + atp_x
citr__L_c <-> citr__L_e
dump_m <-> dump_c
akg_c + succ_m <-> akg_m + succ_c
fum_c + mal__L_m <-> fum_m + mal__L_c
so4_m + succ_c <-> so4_c + succ_m
so3_m + succ_c <-> so3_c + succ_m
orot_e <-> orot_c
r5p_c <-> r5p_r
ru5p__D_c <-> ru5p__D_r
udpg_c <-> udpg_r
uacgam_c + ump_r <-> uacgam_r + ump_c
atp_c + pi_m <-> atp_m + pi_c
atp_c + adp_l <-> adp_c + atp_l
fad_e <-> fad_c
pydx5p_e <-> pydx5p_c
akg_e + na1_e <-> akg_c + na1_c
ac_e + na1_e <-> ac_c + na1_c
gthrd_c + pi_m <-> gthrd_m + pi_c
cmp_c <-> cmp_r
utp_c <-> utp_e
ala_B_c <-> ala_B_e
ptrc_m <-> ptrc_c
acgam_c <-> acgam_r
acgam_l <-> acgam_r
glu__L_m + pro__L_c <-> glu__L_c + pro__L_m
thym_c <-> thym_m
3pg_m <-> 3pg_c
acetone_m <-> acetone_e
taur_c <-> taur_x
hdca_l <-> hdca_r
creat_c <-> creat_e
citr__L_c + orn_e <-> citr__L_e + orn_c
citr__L_c + orn_m <-> citr__L_m + orn_c
dgmp_m <-> dgmp_c
mev__R_c <-> mev__R_x
bilirub_c + na1_c <-> bilirub_r + na1_r
bilirub_e + na1_e <-> bilirub_c + na1_c
fol_c <-> fol_m
fol_e <-> fol_c
acmana_r <-> acmana_e
cholate_c <-> cholate_r
ptth_m <-> ptth_c
56dthm_m <-> 56dthm_c
lanost_r <-> lanost_x
C02528_c <-> C02528_r
HC01231_c <-> HC01231_m
na1_e + tchola_e <-> na1_c + tchola_c
dcholcoa_r <-> dcholcoa_c
dcholcoa_x <-> dcholcoa_c
C02470_c <-> C02470_e
dad_2_e + na1_e <-> dad_2_c + na1_c
dcyt_e + na1_e <-> dcyt_c + na1_c
dgsn_e + na1_e <-> dgsn_c + na1_c
chsterol_l <-> chsterol_r
his__L_l <-> his__L_c
tyr__L_c <-> tyr__L_m
atp_c <-> atp_e
dtmp_c <-> dtmp_m
asp__L_e + na1_e <-> asp__L_c + na1_c
akg_c + icit_x <-> akg_x + icit_c
2obut_c + h_c <-> 2obut_m + h_m
cdpchol_c <-> cdpchol_r
fad_c + fadh2_m <-> fad_m + fadh2_c
ppcoa_c <-> ppcoa_x
lnlccoa_c <-> lnlccoa_r
lnlnca_l <-> lnlnca_r
lnlnca_c <-> lnlnca_l
crn_m + ppcoa_c <-> crn_c + ppcoa_m
btcoa_m + crn_c <-> btcoa_c + crn_m
fald_e <-> fald_c
dhap_c <-> dhap_x
trdrd_c <-> trdrd_m
2obut_m + h_c <-> 2obut_c + h_m
h_c + phe__L_m <-> h_m + phe__L_c
acac_c + pyr_m <-> acac_m + pyr_c
C02528_e + 2.0 na1_e <-> C02528_c + 2.0 na1_c
2.0 na1_e + tdchola_e <-> 2.0 na1_c + tdchola_c
HC02192_e + 2.0 na1_e <-> HC02192_c + 2.0 na1_c
HC02193_e + 2.0 na1_e <-> HC02193_c + 2.0 na1_c
HC02195_e + 2.0 na1_e <-> HC02195_c + 2.0 na1_c
HC02196_e + 2.0 na1_e <-> HC02196_c + 2.0 na1_c
bilirub_e <-> bilirub_c
na1_e + cl_e + taur_e <-> na1_c + cl_c + taur_c
gln__L_c + gly_e <-> gln__L_e + gly_c
gly_e + met__L_c <-> gly_c + met__L_e
gly_e + trp__L_c <-> gly_c + trp__L_e
gly_e + phe__L_c <-> gly_c + phe__L_e
gly_e + tyr__L_c <-> gly_c + tyr__L_e
gly_e + leu__L_c <-> gly_c + leu__L_e
gly_e + pro__L_c <-> gly_c + pro__L_e
asn__L_c + gly_e <-> asn__L_e + gly_c
gly_e + val__L_c <-> gly_c + val__L_e
gly_e + hom__L_c <-> gly_c + hom__L_e
gly_e + ile__L_c <-> gly_c + ile__L_e
ala__L_e + ser__L_c <-> ala__L_c + ser__L_e
ala__L_e + met__L_c <-> ala__L_c + met__L_e
ala__L_e + trp__L_c <-> ala__L_c + trp__L_e
ala__L_e + phe__L_c <-> ala__L_c + phe__L_e
ala__L_e + tyr__L_c <-> ala__L_c + tyr__L_e
ala__L_e + cys__L_c <-> ala__L_c + cys__L_e
ala__L_e + leu__L_c <-> ala__L_c + leu__L_e
ala__L_e + pro__L_c <-> ala__L_c + pro__L_e
ala__L_e + asn__L_c <-> ala__L_c + asn__L_e
ala__L_e + val__L_c <-> ala__L_c + val__L_e
ala__L_e + thr__L_c <-> ala__L_c + thr__L_e
ala__L_e + hom__L_c <-> ala__L_c + hom__L_e
ala__L_e + ile__L_c <-> ala__L_c + ile__L_e
gln__L_e + met__L_c <-> gln__L_c + met__L_e
gln__L_e + trp__L_c <-> gln__L_c + trp__L_e
gln__L_e + phe__L_c <-> gln__L_c + phe__L_e
gln__L_e + tyr__L_c <-> gln__L_c + tyr__L_e
gln__L_e + leu__L_c <-> gln__L_c + leu__L_e
gln__L_e + pro__L_c <-> gln__L_c + pro__L_e
asn__L_c + gln__L_e <-> asn__L_e + gln__L_c
gln__L_e + val__L_c <-> gln__L_c + val__L_e
gln__L_e + hom__L_c <-> gln__L_c + hom__L_e
gln__L_e + ile__L_c <-> gln__L_c + ile__L_e
met__L_c + ser__L_e <-> met__L_e + ser__L_c
ser__L_e + trp__L_c <-> ser__L_c + trp__L_e
phe__L_c + ser__L_e <-> phe__L_e + ser__L_c
ser__L_e + tyr__L_c <-> ser__L_c + tyr__L_e
cys__L_c + ser__L_e <-> cys__L_e + ser__L_c
leu__L_c + ser__L_e <-> leu__L_e + ser__L_c
pro__L_c + ser__L_e <-> pro__L_e + ser__L_c
asn__L_c + ser__L_e <-> asn__L_e + ser__L_c
ser__L_e + val__L_c <-> ser__L_c + val__L_e
ser__L_e + thr__L_c <-> ser__L_c + thr__L_e
hom__L_c + ser__L_e <-> hom__L_e + ser__L_c
ile__L_c + ser__L_e <-> ile__L_e + ser__L_c
met__L_e + trp__L_c <-> met__L_c + trp__L_e
met__L_e + phe__L_c <-> met__L_c + phe__L_e
met__L_e + tyr__L_c <-> met__L_c + tyr__L_e
cys__L_c + met__L_e <-> cys__L_e + met__L_c
met__L_e + pro__L_c <-> met__L_c + pro__L_e
asn__L_c + met__L_e <-> asn__L_e + met__L_c
met__L_e + val__L_c <-> met__L_c + val__L_e
met__L_e + thr__L_c <-> met__L_c + thr__L_e
hom__L_c + met__L_e <-> hom__L_e + met__L_c
ile__L_c + met__L_e <-> ile__L_e + met__L_c
phe__L_c + trp__L_e <-> phe__L_e + trp__L_c
trp__L_e + tyr__L_c <-> trp__L_c + tyr__L_e
cys__L_c + trp__L_e <-> cys__L_e + trp__L_c
leu__L_c + trp__L_e <-> leu__L_e + trp__L_c
pro__L_c + trp__L_e <-> pro__L_e + trp__L_c
asn__L_c + trp__L_e <-> asn__L_e + trp__L_c
trp__L_e + val__L_c <-> trp__L_c + val__L_e
thr__L_c + trp__L_e <-> thr__L_e + trp__L_c
hom__L_c + trp__L_e <-> hom__L_e + trp__L_c
ile__L_c + trp__L_e <-> ile__L_e + trp__L_c
phe__L_e + pro__L_c <-> phe__L_c + pro__L_e
hom__L_c + phe__L_e <-> hom__L_e + phe__L_c
cys__L_c + tyr__L_e <-> cys__L_e + tyr__L_c
leu__L_c + tyr__L_e <-> leu__L_e + tyr__L_c
pro__L_c + tyr__L_e <-> pro__L_e + tyr__L_c
asn__L_c + tyr__L_e <-> asn__L_e + tyr__L_c
tyr__L_e + val__L_c <-> tyr__L_c + val__L_e
thr__L_c + tyr__L_e <-> thr__L_e + tyr__L_c
hom__L_c + tyr__L_e <-> hom__L_e + tyr__L_c
ile__L_c + tyr__L_e <-> ile__L_e + tyr__L_c
cys__L_e + leu__L_c <-> cys__L_c + leu__L_e
cys__L_e + pro__L_c <-> cys__L_c + pro__L_e
asn__L_c + cys__L_e <-> asn__L_e + cys__L_c
cys__L_e + val__L_c <-> cys__L_c + val__L_e
cys__L_e + thr__L_c <-> cys__L_c + thr__L_e
cys__L_e + hom__L_c <-> cys__L_c + hom__L_e
cys__L_e + ile__L_c <-> cys__L_c + ile__L_e
leu__L_e + pro__L_c <-> leu__L_c + pro__L_e
asn__L_c + leu__L_e <-> asn__L_e + leu__L_c
leu__L_e + thr__L_c <-> leu__L_c + thr__L_e
hom__L_c + leu__L_e <-> hom__L_e + leu__L_c
asn__L_c + pro__L_e <-> asn__L_e + pro__L_c
pro__L_e + val__L_c <-> pro__L_c + val__L_e
pro__L_e + thr__L_c <-> pro__L_c + thr__L_e
hom__L_c + pro__L_e <-> hom__L_e + pro__L_c
ile__L_c + pro__L_e <-> ile__L_e + pro__L_c
asn__L_e + val__L_c <-> asn__L_c + val__L_e
asn__L_e + thr__L_c <-> asn__L_c + thr__L_e
asn__L_e + hom__L_c <-> asn__L_c + hom__L_e
asn__L_e + ile__L_c <-> asn__L_c + ile__L_e
thr__L_c + val__L_e <-> thr__L_e + val__L_c
hom__L_c + val__L_e <-> hom__L_e + val__L_c
ile__L_c + val__L_e <-> ile__L_e + val__L_c
hom__L_c + thr__L_e <-> hom__L_e + thr__L_c
ile__L_c + thr__L_e <-> ile__L_e + thr__L_c
hom__L_e + ile__L_c <-> hom__L_c + ile__L_e
lys__L_e + orn_c <-> lys__L_c + orn_e
his__L_c + lys__L_e <-> his__L_e + lys__L_c
citr__L_c + lys__L_e <-> citr__L_e + lys__L_c
arg__L_e + his__L_c <-> arg__L_c + his__L_e
arg__L_e + citr__L_c <-> arg__L_c + citr__L_e
his__L_c + orn_e <-> his__L_e + orn_c
citr__L_c + his__L_e <-> citr__L_e + his__L_c
ala__L_c + gly_e + na1_e <-> ala__L_e + gly_c + na1_c
gln__L_c + gly_e + na1_e <-> gln__L_e + gly_c + na1_c
gly_e + na1_e + ser__L_c <-> gly_c + na1_c + ser__L_e
gly_e + met__L_c + na1_e <-> gly_c + met__L_e + na1_c
gly_e + na1_e + trp__L_c <-> gly_c + na1_c + trp__L_e
gly_e + na1_e + phe__L_c <-> gly_c + na1_c + phe__L_e
gly_e + na1_e + tyr__L_c <-> gly_c + na1_c + tyr__L_e
cys__L_c + gly_e + na1_e <-> cys__L_e + gly_c + na1_c
gly_e + leu__L_c + na1_e <-> gly_c + leu__L_e + na1_c
gly_e + na1_e + pro__L_c <-> gly_c + na1_c + pro__L_e
asn__L_c + gly_e + na1_e <-> asn__L_e + gly_c + na1_c
gly_e + na1_e + val__L_c <-> gly_c + na1_c + val__L_e
gly_e + na1_e + thr__L_c <-> gly_c + na1_c + thr__L_e
gly_e + hom__L_c + na1_e <-> gly_c + hom__L_e + na1_c
gly_e + ile__L_c + na1_e <-> gly_c + ile__L_e + na1_c
ala__L_e + gly_c + na1_e <-> ala__L_c + gly_e + na1_c
ala__L_e + met__L_c + na1_e <-> ala__L_c + met__L_e + na1_c
ala__L_e + na1_e + trp__L_c <-> ala__L_c + na1_c + trp__L_e
ala__L_e + na1_e + phe__L_c <-> ala__L_c + na1_c + phe__L_e
ala__L_e + na1_e + tyr__L_c <-> ala__L_c + na1_c + tyr__L_e
ala__L_e + leu__L_c + na1_e <-> ala__L_c + leu__L_e + na1_c
ala__L_e + na1_e + pro__L_c <-> ala__L_c + na1_c + pro__L_e
ala__L_e + na1_e + val__L_c <-> ala__L_c + na1_c + val__L_e
ala__L_e + hom__L_c + na1_e <-> ala__L_c + hom__L_e + na1_c
ala__L_e + ile__L_c + na1_e <-> ala__L_c + ile__L_e + na1_c
gln__L_e + gly_c + na1_e <-> gln__L_c + gly_e + na1_c
gln__L_e + met__L_c + na1_e <-> gln__L_c + met__L_e + na1_c
gln__L_e + na1_e + trp__L_c <-> gln__L_c + na1_c + trp__L_e
gln__L_e + na1_e + phe__L_c <-> gln__L_c + na1_c + phe__L_e
gln__L_e + na1_e + tyr__L_c <-> gln__L_c + na1_c + tyr__L_e
gln__L_e + leu__L_c + na1_e <-> gln__L_c + leu__L_e + na1_c
gln__L_e + na1_e + pro__L_c <-> gln__L_c + na1_c + pro__L_e
gln__L_e + na1_e + val__L_c <-> gln__L_c + na1_c + val__L_e
gln__L_e + hom__L_c + na1_e <-> gln__L_c + hom__L_e + na1_c
gln__L_e + ile__L_c + na1_e <-> gln__L_c + ile__L_e + na1_c
gly_c + na1_e + ser__L_e <-> gly_e + na1_c + ser__L_c
met__L_c + na1_e + ser__L_e <-> met__L_e + na1_c + ser__L_c
na1_e + ser__L_e + trp__L_c <-> na1_c + ser__L_c + trp__L_e
na1_e + phe__L_c + ser__L_e <-> na1_c + phe__L_e + ser__L_c
na1_e + ser__L_e + tyr__L_c <-> na1_c + ser__L_c + tyr__L_e
leu__L_c + na1_e + ser__L_e <-> leu__L_e + na1_c + ser__L_c
na1_e + pro__L_c + ser__L_e <-> na1_c + pro__L_e + ser__L_c
na1_e + ser__L_e + val__L_c <-> na1_c + ser__L_c + val__L_e
hom__L_c + na1_e + ser__L_e <-> hom__L_e + na1_c + ser__L_c
ile__L_c + na1_e + ser__L_e <-> ile__L_e + na1_c + ser__L_c
gly_c + met__L_e + na1_e <-> gly_e + met__L_c + na1_c
ala__L_c + met__L_e + na1_e <-> ala__L_e + met__L_c + na1_c
gln__L_c + met__L_e + na1_e <-> gln__L_e + met__L_c + na1_c
met__L_e + na1_e + ser__L_c <-> met__L_c + na1_c + ser__L_e
met__L_e + na1_e + trp__L_c <-> met__L_c + na1_c + trp__L_e
met__L_e + na1_e + phe__L_c <-> met__L_c + na1_c + phe__L_e
met__L_e + na1_e + tyr__L_c <-> met__L_c + na1_c + tyr__L_e
cys__L_c + met__L_e + na1_e <-> cys__L_e + met__L_c + na1_c
leu__L_c + met__L_e + na1_e <-> leu__L_e + met__L_c + na1_c
met__L_e + na1_e + pro__L_c <-> met__L_c + na1_c + pro__L_e
asn__L_c + met__L_e + na1_e <-> asn__L_e + met__L_c + na1_c
met__L_e + na1_e + val__L_c <-> met__L_c + na1_c + val__L_e
met__L_e + na1_e + thr__L_c <-> met__L_c + na1_c + thr__L_e
hom__L_c + met__L_e + na1_e <-> hom__L_e + met__L_c + na1_c
ile__L_c + met__L_e + na1_e <-> ile__L_e + met__L_c + na1_c
gly_c + na1_e + trp__L_e <-> gly_e + na1_c + trp__L_c
ala__L_c + na1_e + trp__L_e <-> ala__L_e + na1_c + trp__L_c
gln__L_c + na1_e + trp__L_e <-> gln__L_e + na1_c + trp__L_c
na1_e + ser__L_c + trp__L_e <-> na1_c + ser__L_e + trp__L_c
met__L_c + na1_e + trp__L_e <-> met__L_e + na1_c + trp__L_c
na1_e + phe__L_c + trp__L_e <-> na1_c + phe__L_e + trp__L_c
na1_e + trp__L_e + tyr__L_c <-> na1_c + trp__L_c + tyr__L_e
cys__L_c + na1_e + trp__L_e <-> cys__L_e + na1_c + trp__L_c
leu__L_c + na1_e + trp__L_e <-> leu__L_e + na1_c + trp__L_c
na1_e + pro__L_c + trp__L_e <-> na1_c + pro__L_e + trp__L_c
asn__L_c + na1_e + trp__L_e <-> asn__L_e + na1_c + trp__L_c
na1_e + trp__L_e + val__L_c <-> na1_c + trp__L_c + val__L_e
na1_e + thr__L_c + trp__L_e <-> na1_c + thr__L_e + trp__L_c
hom__L_c + na1_e + trp__L_e <-> hom__L_e + na1_c + trp__L_c
ile__L_c + na1_e + trp__L_e <-> ile__L_e + na1_c + trp__L_c
gly_c + na1_e + phe__L_e <-> gly_e + na1_c + phe__L_c
ala__L_c + na1_e + phe__L_e <-> ala__L_e + na1_c + phe__L_c
gln__L_c + na1_e + phe__L_e <-> gln__L_e + na1_c + phe__L_c
na1_e + phe__L_e + ser__L_c <-> na1_c + phe__L_c + ser__L_e
met__L_c + na1_e + phe__L_e <-> met__L_e + na1_c + phe__L_c
na1_e + phe__L_e + trp__L_c <-> na1_c + phe__L_c + trp__L_e
na1_e + phe__L_e + tyr__L_c <-> na1_c + phe__L_c + tyr__L_e
cys__L_c + na1_e + phe__L_e <-> cys__L_e + na1_c + phe__L_c
leu__L_c + na1_e + phe__L_e <-> leu__L_e + na1_c + phe__L_c
na1_e + phe__L_e + pro__L_c <-> na1_c + phe__L_c + pro__L_e
asn__L_c + na1_e + phe__L_e <-> asn__L_e + na1_c + phe__L_c
na1_e + phe__L_e + val__L_c <-> na1_c + phe__L_c + val__L_e
na1_e + phe__L_e + thr__L_c <-> na1_c + phe__L_c + thr__L_e
hom__L_c + na1_e + phe__L_e <-> hom__L_e + na1_c + phe__L_c
ile__L_c + na1_e + phe__L_e <-> ile__L_e + na1_c + phe__L_c
gly_c + na1_e + tyr__L_e <-> gly_e + na1_c + tyr__L_c
ala__L_c + na1_e + tyr__L_e <-> ala__L_e + na1_c + tyr__L_c
gln__L_c + na1_e + tyr__L_e <-> gln__L_e + na1_c + tyr__L_c
na1_e + ser__L_c + tyr__L_e <-> na1_c + ser__L_e + tyr__L_c
met__L_c + na1_e + tyr__L_e <-> met__L_e + na1_c + tyr__L_c
na1_e + trp__L_c + tyr__L_e <-> na1_c + trp__L_e + tyr__L_c
na1_e + phe__L_c + tyr__L_e <-> na1_c + phe__L_e + tyr__L_c
cys__L_c + na1_e + tyr__L_e <-> cys__L_e + na1_c + tyr__L_c
leu__L_c + na1_e + tyr__L_e <-> leu__L_e + na1_c + tyr__L_c
na1_e + pro__L_c + tyr__L_e <-> na1_c + pro__L_e + tyr__L_c
asn__L_c + na1_e + tyr__L_e <-> asn__L_e + na1_c + tyr__L_c
na1_e + tyr__L_e + val__L_c <-> na1_c + tyr__L_c + val__L_e
na1_e + thr__L_c + tyr__L_e <-> na1_c + thr__L_e + tyr__L_c
hom__L_c + na1_e + tyr__L_e <-> hom__L_e + na1_c + tyr__L_c
ile__L_c + na1_e + tyr__L_e <-> ile__L_e + na1_c + tyr__L_c
cys__L_e + gly_c + na1_e <-> cys__L_c + gly_e + na1_c
cys__L_e + met__L_c + na1_e <-> cys__L_c + met__L_e + na1_c
cys__L_e + na1_e + trp__L_c <-> cys__L_c + na1_c + trp__L_e
cys__L_e + na1_e + phe__L_c <-> cys__L_c + na1_c + phe__L_e
cys__L_e + na1_e + tyr__L_c <-> cys__L_c + na1_c + tyr__L_e
cys__L_e + leu__L_c + na1_e <-> cys__L_c + leu__L_e + na1_c
cys__L_e + na1_e + pro__L_c <-> cys__L_c + na1_c + pro__L_e
cys__L_e + na1_e + val__L_c <-> cys__L_c + na1_c + val__L_e
cys__L_e + hom__L_c + na1_e <-> cys__L_c + hom__L_e + na1_c
cys__L_e + ile__L_c + na1_e <-> cys__L_c + ile__L_e + na1_c
gly_c + leu__L_e + na1_e <-> gly_e + leu__L_c + na1_c
ala__L_c + leu__L_e + na1_e <-> ala__L_e + leu__L_c + na1_c
gln__L_c + leu__L_e + na1_e <-> gln__L_e + leu__L_c + na1_c
leu__L_e + na1_e + ser__L_c <-> leu__L_c + na1_c + ser__L_e
leu__L_e + met__L_c + na1_e <-> leu__L_c + met__L_e + na1_c
leu__L_e + na1_e + trp__L_c <-> leu__L_c + na1_c + trp__L_e
leu__L_e + na1_e + phe__L_c <-> leu__L_c + na1_c + phe__L_e
leu__L_e + na1_e + tyr__L_c <-> leu__L_c + na1_c + tyr__L_e
cys__L_c + leu__L_e + na1_e <-> cys__L_e + leu__L_c + na1_c
leu__L_e + na1_e + pro__L_c <-> leu__L_c + na1_c + pro__L_e
asn__L_c + leu__L_e + na1_e <-> asn__L_e + leu__L_c + na1_c
leu__L_e + na1_e + val__L_c <-> leu__L_c + na1_c + val__L_e
leu__L_e + na1_e + thr__L_c <-> leu__L_c + na1_c + thr__L_e
hom__L_c + leu__L_e + na1_e <-> hom__L_e + leu__L_c + na1_c
ile__L_c + leu__L_e + na1_e <-> ile__L_e + leu__L_c + na1_c
gly_c + na1_e + pro__L_e <-> gly_e + na1_c + pro__L_c
ala__L_c + na1_e + pro__L_e <-> ala__L_e + na1_c + pro__L_c
gln__L_c + na1_e + pro__L_e <-> gln__L_e + na1_c + pro__L_c
na1_e + pro__L_e + ser__L_c <-> na1_c + pro__L_c + ser__L_e
met__L_c + na1_e + pro__L_e <-> met__L_e + na1_c + pro__L_c
na1_e + pro__L_e + trp__L_c <-> na1_c + pro__L_c + trp__L_e
na1_e + phe__L_c + pro__L_e <-> na1_c + phe__L_e + pro__L_c
na1_e + pro__L_e + tyr__L_c <-> na1_c + pro__L_c + tyr__L_e
cys__L_c + na1_e + pro__L_e <-> cys__L_e + na1_c + pro__L_c
leu__L_c + na1_e + pro__L_e <-> leu__L_e + na1_c + pro__L_c
asn__L_c + na1_e + pro__L_e <-> asn__L_e + na1_c + pro__L_c
na1_e + pro__L_e + val__L_c <-> na1_c + pro__L_c + val__L_e
na1_e + pro__L_e + thr__L_c <-> na1_c + pro__L_c + thr__L_e
hom__L_c + na1_e + pro__L_e <-> hom__L_e + na1_c + pro__L_c
ile__L_c + na1_e + pro__L_e <-> ile__L_e + na1_c + pro__L_c
asn__L_e + gly_c + na1_e <-> asn__L_c + gly_e + na1_c
asn__L_e + met__L_c + na1_e <-> asn__L_c + met__L_e + na1_c
asn__L_e + na1_e + trp__L_c <-> asn__L_c + na1_c + trp__L_e
asn__L_e + na1_e + phe__L_c <-> asn__L_c + na1_c + phe__L_e
asn__L_e + na1_e + tyr__L_c <-> asn__L_c + na1_c + tyr__L_e
asn__L_e + leu__L_c + na1_e <-> asn__L_c + leu__L_e + na1_c
asn__L_e + na1_e + pro__L_c <-> asn__L_c + na1_c + pro__L_e
asn__L_e + na1_e + val__L_c <-> asn__L_c + na1_c + val__L_e
asn__L_e + hom__L_c + na1_e <-> asn__L_c + hom__L_e + na1_c
asn__L_e + ile__L_c + na1_e <-> asn__L_c + ile__L_e + na1_c
gly_c + na1_e + val__L_e <-> gly_e + na1_c + val__L_c
ala__L_c + na1_e + val__L_e <-> ala__L_e + na1_c + val__L_c
gln__L_c + na1_e + val__L_e <-> gln__L_e + na1_c + val__L_c
na1_e + ser__L_c + val__L_e <-> na1_c + ser__L_e + val__L_c
met__L_c + na1_e + val__L_e <-> met__L_e + na1_c + val__L_c
na1_e + trp__L_c + val__L_e <-> na1_c + trp__L_e + val__L_c
na1_e + phe__L_c + val__L_e <-> na1_c + phe__L_e + val__L_c
na1_e + tyr__L_c + val__L_e <-> na1_c + tyr__L_e + val__L_c
cys__L_c + na1_e + val__L_e <-> cys__L_e + na1_c + val__L_c
leu__L_c + na1_e + val__L_e <-> leu__L_e + na1_c + val__L_c
na1_e + pro__L_c + val__L_e <-> na1_c + pro__L_e + val__L_c
asn__L_c + na1_e + val__L_e <-> asn__L_e + na1_c + val__L_c
na1_e + thr__L_c + val__L_e <-> na1_c + thr__L_e + val__L_c
hom__L_c + na1_e + val__L_e <-> hom__L_e + na1_c + val__L_c
ile__L_c + na1_e + val__L_e <-> ile__L_e + na1_c + val__L_c
gly_c + na1_e + thr__L_e <-> gly_e + na1_c + thr__L_c
met__L_c + na1_e + thr__L_e <-> met__L_e + na1_c + thr__L_c
na1_e + thr__L_e + trp__L_c <-> na1_c + thr__L_c + trp__L_e
na1_e + phe__L_c + thr__L_e <-> na1_c + phe__L_e + thr__L_c
na1_e + thr__L_e + tyr__L_c <-> na1_c + thr__L_c + tyr__L_e
leu__L_c + na1_e + thr__L_e <-> leu__L_e + na1_c + thr__L_c
na1_e + pro__L_c + thr__L_e <-> na1_c + pro__L_e + thr__L_c
na1_e + thr__L_e + val__L_c <-> na1_c + thr__L_c + val__L_e
hom__L_c + na1_e + thr__L_e <-> hom__L_e + na1_c + thr__L_c
ile__L_c + na1_e + thr__L_e <-> ile__L_e + na1_c + thr__L_c
gly_c + hom__L_e + na1_e <-> gly_e + hom__L_c + na1_c
ala__L_c + hom__L_e + na1_e <-> ala__L_e + hom__L_c + na1_c
gln__L_c + hom__L_e + na1_e <-> gln__L_e + hom__L_c + na1_c
hom__L_e + na1_e + ser__L_c <-> hom__L_c + na1_c + ser__L_e
hom__L_e + met__L_c + na1_e <-> hom__L_c + met__L_e + na1_c
hom__L_e + na1_e + trp__L_c <-> hom__L_c + na1_c + trp__L_e
hom__L_e + na1_e + phe__L_c <-> hom__L_c + na1_c + phe__L_e
hom__L_e + na1_e + tyr__L_c <-> hom__L_c + na1_c + tyr__L_e
cys__L_c + hom__L_e + na1_e <-> cys__L_e + hom__L_c + na1_c
hom__L_e + leu__L_c + na1_e <-> hom__L_c + leu__L_e + na1_c
hom__L_e + na1_e + pro__L_c <-> hom__L_c + na1_c + pro__L_e
asn__L_c + hom__L_e + na1_e <-> asn__L_e + hom__L_c + na1_c
hom__L_e + na1_e + val__L_c <-> hom__L_c + na1_c + val__L_e
hom__L_e + na1_e + thr__L_c <-> hom__L_c + na1_c + thr__L_e
hom__L_e + ile__L_c + na1_e <-> hom__L_c + ile__L_e + na1_c
gly_c + ile__L_e + na1_e <-> gly_e + ile__L_c + na1_c
ala__L_c + ile__L_e + na1_e <-> ala__L_e + ile__L_c + na1_c
gln__L_c + ile__L_e + na1_e <-> gln__L_e + ile__L_c + na1_c
ile__L_e + na1_e + ser__L_c <-> ile__L_c + na1_c + ser__L_e
ile__L_e + met__L_c + na1_e <-> ile__L_c + met__L_e + na1_c
ile__L_e + na1_e + trp__L_c <-> ile__L_c + na1_c + trp__L_e
ile__L_e + na1_e + phe__L_c <-> ile__L_c + na1_c + phe__L_e
ile__L_e + na1_e + tyr__L_c <-> ile__L_c + na1_c + tyr__L_e
cys__L_c + ile__L_e + na1_e <-> cys__L_e + ile__L_c + na1_c
ile__L_e + leu__L_c + na1_e <-> ile__L_c + leu__L_e + na1_c
ile__L_e + na1_e + pro__L_c <-> ile__L_c + na1_c + pro__L_e
asn__L_c + ile__L_e + na1_e <-> asn__L_e + ile__L_c + na1_c
ile__L_e + na1_e + val__L_c <-> ile__L_c + na1_c + val__L_e
ile__L_e + na1_e + thr__L_c <-> ile__L_c + na1_c + thr__L_e
hom__L_c + ile__L_e + na1_e <-> hom__L_e + ile__L_c + na1_c
gly_e + lys__L_c + na1_e <-> gly_c + lys__L_e + na1_c
arg__L_c + gly_e + na1_e <-> arg__L_e + gly_c + na1_c
gly_e + na1_e + orn_c <-> gly_c + na1_c + orn_e
gly_e + his__L_c + na1_e <-> gly_c + his__L_e + na1_c
citr__L_c + gly_e + na1_e <-> citr__L_e + gly_c + na1_c
ala__L_e + lys__L_c + na1_e <-> ala__L_c + lys__L_e + na1_c
ala__L_e + arg__L_c + na1_e <-> ala__L_c + arg__L_e + na1_c
ala__L_e + na1_e + orn_c <-> ala__L_c + na1_c + orn_e
ala__L_e + his__L_c + na1_e <-> ala__L_c + his__L_e + na1_c
ala__L_e + citr__L_c + na1_e <-> ala__L_c + citr__L_e + na1_c
gln__L_e + lys__L_c + na1_e <-> gln__L_c + lys__L_e + na1_c
arg__L_c + gln__L_e + na1_e <-> arg__L_e + gln__L_c + na1_c
gln__L_e + na1_e + orn_c <-> gln__L_c + na1_c + orn_e
gln__L_e + his__L_c + na1_e <-> gln__L_c + his__L_e + na1_c
citr__L_c + gln__L_e + na1_e <-> citr__L_e + gln__L_c + na1_c
arg__L_c + na1_e + ser__L_e <-> arg__L_e + na1_c + ser__L_c
na1_e + orn_c + ser__L_e <-> na1_c + orn_e + ser__L_c
his__L_c + na1_e + ser__L_e <-> his__L_e + na1_c + ser__L_c
citr__L_c + na1_e + ser__L_e <-> citr__L_e + na1_c + ser__L_c
lys__L_c + met__L_e + na1_e <-> lys__L_e + met__L_c + na1_c
arg__L_c + met__L_e + na1_e <-> arg__L_e + met__L_c + na1_c
met__L_e + na1_e + orn_c <-> met__L_c + na1_c + orn_e
his__L_c + met__L_e + na1_e <-> his__L_e + met__L_c + na1_c
citr__L_c + met__L_e + na1_e <-> citr__L_e + met__L_c + na1_c
lys__L_c + na1_e + trp__L_e <-> lys__L_e + na1_c + trp__L_c
arg__L_c + na1_e + trp__L_e <-> arg__L_e + na1_c + trp__L_c
na1_e + orn_c + trp__L_e <-> na1_c + orn_e + trp__L_c
his__L_c + na1_e + trp__L_e <-> his__L_e + na1_c + trp__L_c
citr__L_c + na1_e + trp__L_e <-> citr__L_e + na1_c + trp__L_c
lys__L_c + na1_e + phe__L_e <-> lys__L_e + na1_c + phe__L_c
arg__L_c + na1_e + phe__L_e <-> arg__L_e + na1_c + phe__L_c
na1_e + orn_c + phe__L_e <-> na1_c + orn_e + phe__L_c
his__L_c + na1_e + phe__L_e <-> his__L_e + na1_c + phe__L_c
citr__L_c + na1_e + phe__L_e <-> citr__L_e + na1_c + phe__L_c
lys__L_c + na1_e + tyr__L_e <-> lys__L_e + na1_c + tyr__L_c
arg__L_c + na1_e + tyr__L_e <-> arg__L_e + na1_c + tyr__L_c
na1_e + orn_c + tyr__L_e <-> na1_c + orn_e + tyr__L_c
his__L_c + na1_e + tyr__L_e <-> his__L_e + na1_c + tyr__L_c
citr__L_c + na1_e + tyr__L_e <-> citr__L_e + na1_c + tyr__L_c
cys__L_e + lys__L_c + na1_e <-> cys__L_c + lys__L_e + na1_c
arg__L_c + cys__L_e + na1_e <-> arg__L_e + cys__L_c + na1_c
cys__L_e + na1_e + orn_c <-> cys__L_c + na1_c + orn_e
cys__L_e + his__L_c + na1_e <-> cys__L_c + his__L_e + na1_c
citr__L_c + cys__L_e + na1_e <-> citr__L_e + cys__L_c + na1_c
leu__L_e + lys__L_c + na1_e <-> leu__L_c + lys__L_e + na1_c
arg__L_c + leu__L_e + na1_e <-> arg__L_e + leu__L_c + na1_c
leu__L_e + na1_e + orn_c <-> leu__L_c + na1_c + orn_e
his__L_c + leu__L_e + na1_e <-> his__L_e + leu__L_c + na1_c
citr__L_c + leu__L_e + na1_e <-> citr__L_e + leu__L_c + na1_c
lys__L_c + na1_e + pro__L_e <-> lys__L_e + na1_c + pro__L_c
arg__L_c + na1_e + pro__L_e <-> arg__L_e + na1_c + pro__L_c
na1_e + orn_c + pro__L_e <-> na1_c + orn_e + pro__L_c
his__L_c + na1_e + pro__L_e <-> his__L_e + na1_c + pro__L_c
citr__L_c + na1_e + pro__L_e <-> citr__L_e + na1_c + pro__L_c
asn__L_e + lys__L_c + na1_e <-> asn__L_c + lys__L_e + na1_c
arg__L_c + asn__L_e + na1_e <-> arg__L_e + asn__L_c + na1_c
asn__L_e + na1_e + orn_c <-> asn__L_c + na1_c + orn_e
asn__L_e + his__L_c + na1_e <-> asn__L_c + his__L_e + na1_c
asn__L_e + citr__L_c + na1_e <-> asn__L_c + citr__L_e + na1_c
lys__L_c + na1_e + val__L_e <-> lys__L_e + na1_c + val__L_c
arg__L_c + na1_e + val__L_e <-> arg__L_e + na1_c + val__L_c
na1_e + orn_c + val__L_e <-> na1_c + orn_e + val__L_c
his__L_c + na1_e + val__L_e <-> his__L_e + na1_c + val__L_c
citr__L_c + na1_e + val__L_e <-> citr__L_e + na1_c + val__L_c
lys__L_c + na1_e + thr__L_e <-> lys__L_e + na1_c + thr__L_c
arg__L_c + na1_e + thr__L_e <-> arg__L_e + na1_c + thr__L_c
na1_e + orn_c + thr__L_e <-> na1_c + orn_e + thr__L_c
his__L_c + na1_e + thr__L_e <-> his__L_e + na1_c + thr__L_c
citr__L_c + na1_e + thr__L_e <-> citr__L_e + na1_c + thr__L_c
hom__L_e + lys__L_c + na1_e <-> hom__L_c + lys__L_e + na1_c
arg__L_c + hom__L_e + na1_e <-> arg__L_e + hom__L_c + na1_c
hom__L_e + na1_e + orn_c <-> hom__L_c + na1_c + orn_e
his__L_c + hom__L_e + na1_e <-> his__L_e + hom__L_c + na1_c
citr__L_c + hom__L_e + na1_e <-> citr__L_e + hom__L_c + na1_c
ile__L_e + lys__L_c + na1_e <-> ile__L_c + lys__L_e + na1_c
arg__L_c + ile__L_e + na1_e <-> arg__L_e + ile__L_c + na1_c
ile__L_e + na1_e + orn_c <-> ile__L_c + na1_c + orn_e
his__L_c + ile__L_e + na1_e <-> his__L_e + ile__L_c + na1_c
citr__L_c + ile__L_e + na1_e <-> citr__L_e + ile__L_c + na1_c
gly_c + lys__L_e <-> gly_e + lys__L_c
ala__L_c + lys__L_e <-> ala__L_e + lys__L_c
gln__L_c + lys__L_e <-> gln__L_e + lys__L_c
lys__L_e + ser__L_c <-> lys__L_c + ser__L_e
lys__L_e + met__L_c <-> lys__L_c + met__L_e
lys__L_e + trp__L_c <-> lys__L_c + trp__L_e
lys__L_e + phe__L_c <-> lys__L_c + phe__L_e
lys__L_e + tyr__L_c <-> lys__L_c + tyr__L_e
cys__L_c + lys__L_e <-> cys__L_e + lys__L_c
leu__L_c + lys__L_e <-> leu__L_e + lys__L_c
lys__L_e + pro__L_c <-> lys__L_c + pro__L_e
asn__L_c + lys__L_e <-> asn__L_e + lys__L_c
lys__L_e + val__L_c <-> lys__L_c + val__L_e
lys__L_e + thr__L_c <-> lys__L_c + thr__L_e
hom__L_c + lys__L_e <-> hom__L_e + lys__L_c
ile__L_c + lys__L_e <-> ile__L_e + lys__L_c
arg__L_e + gly_c <-> arg__L_c + gly_e
ala__L_c + arg__L_e <-> ala__L_e + arg__L_c
arg__L_e + gln__L_c <-> arg__L_c + gln__L_e
arg__L_e + ser__L_c <-> arg__L_c + ser__L_e
arg__L_e + met__L_c <-> arg__L_c + met__L_e
arg__L_e + trp__L_c <-> arg__L_c + trp__L_e
arg__L_e + phe__L_c <-> arg__L_c + phe__L_e
arg__L_e + tyr__L_c <-> arg__L_c + tyr__L_e
arg__L_e + cys__L_c <-> arg__L_c + cys__L_e
arg__L_e + leu__L_c <-> arg__L_c + leu__L_e
arg__L_e + pro__L_c <-> arg__L_c + pro__L_e
arg__L_e + asn__L_c <-> arg__L_c + asn__L_e
arg__L_e + val__L_c <-> arg__L_c + val__L_e
arg__L_e + thr__L_c <-> arg__L_c + thr__L_e
arg__L_e + hom__L_c <-> arg__L_c + hom__L_e
arg__L_e + ile__L_c <-> arg__L_c + ile__L_e
gly_c + orn_e <-> gly_e + orn_c
gln__L_c + orn_e <-> gln__L_e + orn_c
orn_e + ser__L_c <-> orn_c + ser__L_e
met__L_c + orn_e <-> met__L_e + orn_c
orn_e + trp__L_c <-> orn_c + trp__L_e
orn_e + phe__L_c <-> orn_c + phe__L_e
orn_e + tyr__L_c <-> orn_c + tyr__L_e
cys__L_c + orn_e <-> cys__L_e + orn_c
orn_e + pro__L_c <-> orn_c + pro__L_e
asn__L_c + orn_e <-> asn__L_e + orn_c
orn_e + val__L_c <-> orn_c + val__L_e
orn_e + thr__L_c <-> orn_c + thr__L_e
hom__L_c + orn_e <-> hom__L_e + orn_c
ile__L_c + orn_e <-> ile__L_e + orn_c
gly_c + his__L_e <-> gly_e + his__L_c
ala__L_c + his__L_e <-> ala__L_e + his__L_c
gln__L_c + his__L_e <-> gln__L_e + his__L_c
his__L_e + ser__L_c <-> his__L_c + ser__L_e
his__L_e + met__L_c <-> his__L_c + met__L_e
his__L_e + trp__L_c <-> his__L_c + trp__L_e
his__L_e + phe__L_c <-> his__L_c + phe__L_e
his__L_e + tyr__L_c <-> his__L_c + tyr__L_e
cys__L_c + his__L_e <-> cys__L_e + his__L_c
his__L_e + leu__L_c <-> his__L_c + leu__L_e
his__L_e + pro__L_c <-> his__L_c + pro__L_e
asn__L_c + his__L_e <-> asn__L_e + his__L_c
his__L_e + val__L_c <-> his__L_c + val__L_e
his__L_e + thr__L_c <-> his__L_c + thr__L_e
his__L_e + hom__L_c <-> his__L_c + hom__L_e
his__L_e + ile__L_c <-> his__L_c + ile__L_e
citr__L_e + gly_c <-> citr__L_c + gly_e
ala__L_c + citr__L_e <-> ala__L_e + citr__L_c
citr__L_e + gln__L_c <-> citr__L_c + gln__L_e
citr__L_e + ser__L_c <-> citr__L_c + ser__L_e
citr__L_e + met__L_c <-> citr__L_c + met__L_e
citr__L_e + trp__L_c <-> citr__L_c + trp__L_e
citr__L_e + phe__L_c <-> citr__L_c + phe__L_e
citr__L_e + tyr__L_c <-> citr__L_c + tyr__L_e
citr__L_e + cys__L_c <-> citr__L_c + cys__L_e
citr__L_e + leu__L_c <-> citr__L_c + leu__L_e
citr__L_e + pro__L_c <-> citr__L_c + pro__L_e
asn__L_c + citr__L_e <-> asn__L_e + citr__L_c
citr__L_e + val__L_c <-> citr__L_c + val__L_e
citr__L_e + thr__L_c <-> citr__L_c + thr__L_e
citr__L_e + hom__L_c <-> citr__L_c + hom__L_e
citr__L_e + ile__L_c <-> citr__L_c + ile__L_e
acac_c + pyr_e <-> acac_e + pyr_c
ac_e + acac_c <-> ac_c + acac_e
acac_c + for_e <-> acac_e + for_c
acac_c + lac__L_e <-> acac_e + lac__L_c
acac_c + retn_e <-> acac_e + retn_c
2hb_e + acac_c <-> 2hb_c + acac_e
2hb_c + pyr_e <-> 2hb_e + pyr_c
2hb_c + ac_e <-> 2hb_e + ac_c
2hb_c + for_e <-> 2hb_e + for_c
2hb_c + lac__L_e <-> 2hb_e + lac__L_c
2hb_c + retn_e <-> 2hb_e + retn_c
akg_c + pyr_e <-> akg_e + pyr_c
ac_c + pyr_e <-> ac_e + pyr_c
for_c + pyr_e <-> for_e + pyr_c
lac__L_c + pyr_e <-> lac__L_e + pyr_c
pyr_e + retn_c <-> pyr_c + retn_e
bhb_c + pyr_e <-> bhb_e + pyr_c
ac_c + akg_e <-> ac_e + akg_c
akg_e + for_c <-> akg_c + for_e
acac_c + akg_e <-> acac_e + akg_c
akg_e + lac__L_c <-> akg_c + lac__L_e
akg_e + retn_c <-> akg_c + retn_e
akg_e + bhb_c <-> akg_c + bhb_e
2hb_c + akg_e <-> 2hb_e + akg_c
ac_e + for_c <-> ac_c + for_e
ac_e + lac__L_c <-> ac_c + lac__L_e
ac_e + retn_c <-> ac_c + retn_e
ac_e + bhb_c <-> ac_c + bhb_e
for_e + lac__L_c <-> for_c + lac__L_e
for_e + retn_c <-> for_c + retn_e
bhb_c + for_e <-> bhb_e + for_c
acac_e + bhb_c <-> acac_c + bhb_e
lac__L_e + retn_c <-> lac__L_c + retn_e
bhb_c + lac__L_e <-> bhb_e + lac__L_c
bhb_c + retn_e <-> bhb_e + retn_c
2hb_c + bhb_e <-> 2hb_e + bhb_c
cholate_e + gthrd_c + hco3_c <-> cholate_c + gthrd_e + hco3_e
gthrd_c + hco3_c + tchola_e <-> gthrd_e + hco3_e + tchola_c
gthrd_c + hco3_c + tdchola_e <-> gthrd_e + hco3_e + tdchola_c
HC02191_e + gthrd_c + hco3_c <-> HC02191_c + gthrd_e + hco3_e
HC02192_e + gthrd_c + hco3_c <-> HC02192_c + gthrd_e + hco3_e
HC02193_e + gthrd_c + hco3_c <-> HC02193_c + gthrd_e + hco3_e
HC02194_e + gthrd_c + hco3_c <-> HC02194_c + gthrd_e + hco3_e
HC02195_e + gthrd_c + hco3_c <-> HC02195_c + gthrd_e + hco3_e
HC02196_e + gthrd_c + hco3_c <-> HC02196_c + gthrd_e + hco3_e
HC02197_e + gthrd_c + hco3_c <-> HC02197_c + gthrd_e + hco3_e
bilirub_e + gthrd_c + hco3_c <-> bilirub_c + gthrd_e + hco3_e
gthrd_c + hco3_c + leuktrC4_e <-> gthrd_e + hco3_e + leuktrC4_c
HC02180_e + gthrd_c + hco3_c <-> HC02180_c + gthrd_e + hco3_e
gthrd_c + hco3_c + hista_e <-> gthrd_e + hco3_e + hista_c
gthrd_c + hco3_c + nrpphr_e <-> gthrd_e + hco3_e + nrpphr_c
gthrd_c + hco3_c + srtn_e <-> gthrd_e + hco3_e + srtn_c
ach_e + gthrd_c + hco3_c <-> ach_c + gthrd_e + hco3_e
dopa_e + gthrd_c + hco3_c <-> dopa_c + gthrd_e + hco3_e
gthrd_c + hco3_c + leuktrA4_e <-> gthrd_e + hco3_e + leuktrA4_c
HC02202_e + gthrd_c + hco3_c <-> HC02202_c + gthrd_e + hco3_e
HC02203_e + gthrd_c + hco3_c <-> HC02203_c + gthrd_e + hco3_e
HC02204_e + gthrd_c + hco3_c <-> HC02204_c + gthrd_e + hco3_e
HC02205_e + gthrd_c + hco3_c <-> HC02205_c + gthrd_e + hco3_e
HC02206_e + gthrd_c + hco3_c <-> HC02206_c + gthrd_e + hco3_e
HC02207_e + gthrd_c + hco3_c <-> HC02207_c + gthrd_e + hco3_e
HC02208_e + gthrd_c + hco3_c <-> HC02208_c + gthrd_e + hco3_e
HC02210_e + gthrd_c + hco3_c <-> HC02210_c + gthrd_e + hco3_e
HC02213_e + gthrd_c + hco3_c <-> HC02213_c + gthrd_e + hco3_e
HC02214_e + gthrd_c + hco3_c <-> HC02214_c + gthrd_e + hco3_e
HC02216_e + gthrd_c + hco3_c <-> HC02216_c + gthrd_e + hco3_e
HC02217_e + gthrd_c + hco3_c <-> HC02217_c + gthrd_e + hco3_e
ach_e <-> ach_c
leuktrC4_e <-> leuktrC4_c
dheas_e <-> dheas_c
HC02202_e <-> HC02202_c
HC02203_e <-> HC02203_c
HC02204_e <-> HC02204_c
HC02205_e <-> HC02205_c
HC02206_e <-> HC02206_c
HC02207_e <-> HC02207_c
HC02208_e <-> HC02208_c
HC02210_e <-> HC02210_c
HC02213_e <-> HC02213_c
HC02214_e <-> HC02214_c
HC02216_e <-> HC02216_c
HC02217_e <-> HC02217_c
cit_m + oxa_c <-> cit_c + oxa_m
icit_m + succ_c <-> icit_c + succ_m
icit_m + oxa_c <-> icit_c + oxa_m
akg_m + cit_c + h_c <-> akg_c + cit_m + h_m
cit_c + h_c + succ_m <-> cit_m + h_m + succ_c
cit_c + h_c + oxa_m <-> cit_m + h_m + oxa_c
akg_m + h_c + icit_c <-> akg_c + h_m + icit_m
h_c + icit_c + succ_m <-> h_m + icit_m + succ_c
h_c + icit_c + mal__L_m <-> h_m + icit_m + mal__L_c
h_c + icit_c + oxa_m <-> h_m + icit_m + oxa_c
icit_m + pep_c <-> icit_c + pep_m
arg__L_c + h_c + lys__L_m <-> arg__L_m + h_m + lys__L_c
h_c + lys__L_m + orn_c <-> h_m + lys__L_c + orn_m
h_c + his__L_c + lys__L_m <-> h_m + his__L_m + lys__L_c
citr__L_c + h_c + lys__L_m <-> citr__L_m + h_m + lys__L_c
arg__L_m + h_c + lys__L_c <-> arg__L_c + h_m + lys__L_m
arg__L_m + h_c + orn_c <-> arg__L_c + h_m + orn_m
arg__L_m + h_c + his__L_c <-> arg__L_c + h_m + his__L_m
arg__L_m + citr__L_c + h_c <-> arg__L_c + citr__L_m + h_m
h_c + lys__L_c + orn_m <-> h_m + lys__L_m + orn_c
arg__L_c + h_c + orn_m <-> arg__L_m + h_m + orn_c
h_c + his__L_c + orn_m <-> h_m + his__L_m + orn_c
h_c + his__L_m + lys__L_c <-> h_m + his__L_c + lys__L_m
arg__L_c + h_c + his__L_m <-> arg__L_m + h_m + his__L_c
h_c + his__L_m + orn_c <-> h_m + his__L_c + orn_m
citr__L_c + h_c + his__L_m <-> citr__L_m + h_m + his__L_c
citr__L_m + h_c + lys__L_c <-> citr__L_c + h_m + lys__L_m
arg__L_c + citr__L_m + h_c <-> arg__L_m + citr__L_c + h_m
h_c + orn_c + citr__L_m <-> h_m + orn_m + citr__L_c
citr__L_m + h_c + his__L_c <-> citr__L_c + h_m + his__L_m
h_c + his__L_m <-> h_m + his__L_c
akg_c + pi_m <-> akg_m + pi_c
oxa_c + pi_m <-> oxa_m + pi_c
adp_m + dgdp_c <-> adp_c + dgdp_m
crn_m + c4crn_c <-> crn_c + c4crn_m
hco3_c + so4_e <-> hco3_e + so4_c
duri_e + na1_e <-> duri_c + na1_c
din_e + na1_e <-> din_c + na1_c
crn_r + hdca_c <-> crn_c + hdca_r
crn_r + ocdcea_c <-> crn_c + ocdcea_r
crn_r + lnlc_c <-> crn_c + lnlc_r
crn_c + lnlnca_r <-> crn_r + lnlnca_c
udpglcur_c <-> udpglcur_r
akg_m + gthrd_c <-> akg_c + gthrd_m
asn__L_e <-> asn__L_c
hom__L_e <-> hom__L_c
hom__L_m <-> hom__L_c
L2aadp6sa_c + L2aadp_m <-> L2aadp6sa_m + L2aadp_c