5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing
(6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide hydro-lyase (ATP-hydrolysing, NADH-forming)
2-Oxoglutarate + Ammonia <=> 4-Oxoglutaramate + H2O
acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
protoheme,NADPH---hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
citrate oxaloacetate-lyase (forming acetate from the pro-S carboxymethyl group of citrate)
2-Oxoglutarate + Thiamin diphosphate <=> 3-Carboxy-1-hydroxypropyl-ThPP + CO2
Ascorbate + Oxygen + H2O <=> Threonate + Oxalate
Aminoacyl-L-methionine + H2O <=> L-Methionine
L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Acetaldehyde + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate
Anthranilate,NADH:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)
anthranilate,NADPH:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)
GDP-mannose + Mannan(n) <=> GDP + Mannan(n+1)
L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating)
uracil hydro-lyase (adding D-ribose 5-phosphate
CMP-N-acetylneuraminate <=> Colominic acid(non-reducing N- or O-acylneuraminyl residue)
Palmitoyl-CoA + Acceptor <=> trans-Hexadec-2-enoyl-CoA + Reduced acceptor
benzoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
4-Hydroxybenzoate + Acceptor + H2O <=> 4-Hydroxybenzaldehyde + Reduced acceptor + Oxygen
4-Hydroxybenzoate + Acetate + NADH + H+ <=> 4-Coumarate + 2 H2O + NAD+
Fatty acid,reduced rubredoxin:oxygen oxidoreductase (omega-hydroxylating)
fatty acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)
Hydroxypyruvate + CO2 <=> Dihydroxyfumarate
Hydrogen cyanide + Acetaldehyde + Ammonia <=> alpha-Aminopropiononitrile + H2O
Benzoate + Acetate + NADH + H+ <=> trans-Cinnamate + 2 H2O + NAD+
D-Glutamate + Peptide <=> D-Glutamyl-peptide
D-xylulose 5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate
Succinate semialdehyde + Hydrogen cyanide + Ammonia <=> gamma-Amino-gamma-cyanobutanoate + H2O
4-Methyl-2-oxopentanoate + CO2 <=> (2S)-2-Isopropyl-3-oxosuccinate
pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)
2-oxoglutarate:[dihydrolipoyllysine-residue succinyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)
3-methyl-2-oxobutanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)
4-methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)
Nicotinate + Glycine + ATP <=> Nicotinurate + AMP + Diphosphate
5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming)
Phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate hydrolysing, 2-carboxy-2-oxoethyl-forming)
ADP-ribose + H2O <=> alpha-D-Ribose 1-phosphate + AMP
Pyridoxine <=> 1-Deoxy-D-xylulose + 4-Hydroxy-L-threonine
2-Oxoadipate + Ammonia + NAD+ <=> 2-Aminomuconate + NADH + H+ + H2O
2-Oxoadipate + Ammonia + NADP+ <=> 2-Aminomuconate + NADPH + H+ + H2O
D-Galacturonate + NAD+ + H2O <=> D-Galactarate + NADH + H+
D-Galacturonate <=> D-Galacturonolactone + H2O
adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate -forming)
Xanthine + H2O <=> 5-Ureido-4-imidazole carboxylate
Histamine + Acetyl-CoA <=> 4-(beta-Acetylaminoethyl)imidazole + CoA
Ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)
Stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)
trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
Prostaglandin H2 + NADPH + H+ <=> Prostaglandin F2alpha + NADP+
Indole + Oxygen + NADPH + H+ <=> Indoxyl + H2O + NADP+
19-oxoandrostenedione,NADPH---hemoprotein reductase:oxygen oxidoreductase (aromatizing, formate-forming)
Estrone + H+ + Oxygen + NADH <=> 2-Hydroxyestrone + NAD+ + H2O
Estrone + H+ + Oxygen + NADPH <=> 2-Hydroxyestrone + NADP+ + H2O
Estrone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxyestrone + NADP+ + H2O
L-Cysteate + NADH + H+ <=> 3-Sulfino-L-alanine + H2O + NAD+
naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
(S)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating)
(S)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating)
(S)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7-hydroxylating)
(R)-Pantoate + NAD+ <=> (R)-4-Dehydropantoate + NADH + H+
Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
Homogentisate + Oxygen + NADPH <=> Gentisate aldehyde + CO2 + NADP+ + H+ + H2O
Homogentisate + Oxygen <=> Gentisate aldehyde + CO2 + H2O
Methylglyoxal + NADPH + H+ <=> Hydroxyacetone + NADP+
Prostaglandin E2 <=> Prostaglandin A2 + H2O
N-Dimethyl-2-aminoethylphosphonate + Activated methyl group <=> N-Trimethyl-2-aminoethylphosphonate
3-Sulfino-L-alanine + NAD+ + H2O <=> 3-Sulfinylpyruvate + Ammonia + NADH + H+
2,5-Dihydroxybenzoate + Hydrogen peroxide <=> Gentisate aldehyde + Oxygen + H2O
2-Keto-D-gluconic acid <=> 2-Dehydro-D-glucono-1,5-lactone + H2O
2-Methylpropanoyl-CoA <=> Branched chain fatty acid
2-Phospho-D-glycerate + ATP <=> 2,3-Bisphospho-D-glycerate + ADP
3-Hydroxyanthranilate <=> 2-Aminophenol + CO2
2 3-Hydroxyanthranilate + 4 Oxygen <=> Cinnavalininate + 2 Superoxide + 2 Hydrogen peroxide + 2 H+
3-Hydroxyanthranilate + S-Adenosyl-L-methionine <=> 3-Methoxyanthranilate + S-Adenosyl-L-homocysteine
N-Acetyl-D-mannosamine + Orthophosphate <=> N-Acetyl-D-mannosamine 6-phosphate + H2O
D-Glyceraldehyde 3-phosphate + Pyruvate <=> 5-(2-Hydroxyethyl)-4-methylthiazole
L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate
Cholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 22(R)-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
sn-Glycero-3-phosphocholine + Carboxylate <=> 2-Acyl-sn-glycero-3-phosphocholine + H2O
1-Acyl-sn-glycerol 3-phosphate + NADP+ <=> Acylglycerone phosphate + NADPH + H+
2-Hydroxymuconate semialdehyde + CO2 <=> 3-Carboxy-2-hydroxymuconate semialdehyde
alpha,alpha-Trehalose + Protein N(pi)-phospho-L-histidine <=> alpha,alpha'-Trehalose 6-phosphate + Protein histidine
Cholic acid <=> 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + H2O
Prostaglandin D2 <=> Prostaglandin J2 + H2O
D-Serine + Amino acid(Arg-) <=> D-Lombricine + Ornithine
(R)-Acetoin + NADP+ <=> Diacetyl + NADPH + H+
Hydrofluoric acid + Glycolate <=> Fluoroacetate + H2O
Nicotine + CO2 + H+ <=> 1-Methylpyrrolinium + Nicotinate
Retinoate + UDP-glucuronate <=> all-trans-Retinoyl-beta-glucuronide + UDP
Tryptophan + Dimethylallyl diphosphate <=> Dimethylallyltryptophan + Diphosphate
S-Adenosyl-L-methionine + DNA adenine <=> S-Adenosyl-L-homocysteine + DNA 6-methylaminopurine
Sphinganine + FAD <=> FADH2 + Sphingosine
4-Pyridoxate + Acceptor <=> 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate + Reduced acceptor
formononetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Pregnan-21-al + NADPH + H+ <=> Pregnan-21-ol + NADP+
UDP-L-arabinofuranose + Arabinan <=> Arabinan + UDP
19-oxotestosterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (aromatizing, formate-forming)
Estradiol-17beta + H+ + Oxygen + NADH <=> 2-Hydroxyestradiol + NAD+ + H2O
Estradiol-17beta + H+ + Oxygen + NADPH <=> Estriol + NADP+ + H2O
Estradiol-17beta + H+ + Oxygen + NADPH <=> 2-Hydroxyestradiol + NADP+ + H2O
Indole-3-acetate + Oxygen <=> 3-Methyldioxyindole + CO2
Indole-3-acetate + Oxygen <=> 2-Formaminobenzoylacetate
dihydrokaempferol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
O-Acetyl-L-serine acetate-lyase (adding N6-substituted adenine)
3-Hydroxypropionyl-CoA + Orthophosphate + ADP <=> 3-Hydroxypropanoate + CoA + ATP
3-Hydroxypropanoate + CoA <=> 3-Hydroxypropionyl-CoA + H2O
Hydroxymethylbilane <=> Uroporphyrinogen I + H2O
(S)-2-Methylbutanoyl-CoA <=> Branched chain fatty acid
2 Monodehydroascorbate <=> Dehydroascorbate + Ascorbate
Uroporphyrinogen III + Acceptor <=> Uroporphyrin III + 6 H+ + Reduced acceptor
2 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Thyroxine + Dehydroalanine + 2 H2O
Sorbitol 6-phosphate + NADP+ <=> Sorbose 1-phosphate + NADPH + H+
5-Amino-2-oxopentanoic acid <=> 1-Pyrroline-2-carboxylate + H2O
5-Amino-2-oxopentanoic acid + Urea <=> 5-Guanidino-2-oxopentanoate + H2O
L-Galactono-1,4-lactone + Acceptor <=> D-Galacturonolactone + Reduced acceptor
18-Hydroxycorticosterone + Reduced adrenal ferredoxin + Oxygen <=> Aldosterone + Oxidized adrenal ferredoxin + 2 H2O
2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate
2-Hydroxy-3-oxopropanoate + Pyruvate <=> 2-Dehydro-3-deoxy-D-glucarate
4-Trimethylammoniobutanal + Glycine <=> (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
7-Dehydrocholesterol + hn <=> Vitamin D3
L-Glutamate 5-semialdehyde <=> (S)-1-Pyrroline-5-carboxylate + H2O
3-Carboxy-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + Thiamin diphosphate
stearoyl-[acyl-carrier protein],reduced-ferredoxin:oxygen oxidoreductase (9,10 cis-dehydrogenating)
(S)-Methylmalonate semialdehyde + CoA + NAD+ <=> (R)-Methylmalonyl-CoA + NADH + H+
Dehydroepiandrosterone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxydehydroepiandrosterone + NADP+ + H2O
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)
4-(2-Aminophenyl)-2,4-dioxobutanoate <=> 4-Hydroxy-2-quinolinecarboxylic acid + H2O
(6aR,11aR)-3,9-dihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6a-hydroxylating)
Lactosylceramide + N-Acetylneuraminate <=> GM3 + H2O
3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 Oxidized adrenal ferredoxin
UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase
UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase
Prostaglandin I2 + H2O <=> 6-Keto-prostaglandin F1alpha
PQQH2 + Propynoate <=> 2-Propynal + PQQ + H2O
Hydroiodic acid + 3-Iodo-L-tyrosine <=> Iodine + L-Tyrosine
Butanal + NADH + H+ <=> 1-Butanol + NAD+
Butanal + NADPH + H+ <=> 1-Butanol + NADP+
Gallate + Methanol <=> 3-O-Methylgallate + H2O
loganin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ring-cleaving)
7-deoxyloganin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7alpha-hydroxylating)
Tropate + Tropine <=> L-Hyoscyamine + H2O
O3-Acetyl-L-serine acetate-lyase (adding hydrogen sulfide)
flavonoid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Stachyose + H2O <=> Raffinose + D-Galactose
Vicianose + Mandelonitrile <=> Vicianin + H2O
L-Dopachrome + 3,4-Dihydroxy-L-phenylalanine <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + Dopaquinone
L-Dopachrome <=> 5,6-Dihydroxyindole + CO2
Mesaconate + H2O <=> L-threo-3-Methylmalate
Mesaconate + CoA <=> 2-Methylfumaryl-CoA + H2O
Morphine + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O <=> Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen
Desmosterol + Acceptor <=> 7-Dehydrodesmosterol + Reduced acceptor
Desmosterol + S-Adenosyl-L-methionine <=> 24-Methylenecholesterol + S-Adenosyl-L-homocysteine
Aminoacetone + CO2 <=> L-2-Amino-3-oxobutanoic acid
(S)-Mandelate + NAD+ <=> alpha-Oxo-benzeneacetic acid + NADH + H+
Monoamide of a dicarboxylic acid amidohydrolase
linoleoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (6,7 cis-dehydrogenating)
carotenoid beta-end group lyase (decyclizing)
(S)-scoulerine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase [(S)-cheilanthifoline-forming]
(S)-N-methylcanadine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-hydroxylating)
Leukotriene B4 + NAD+ <=> 12-Keto-leukotriene B4 + H+ + NADH
Leukotriene B4 + NADP+ <=> 12-Keto-leukotriene B4 + H+ + NADPH
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating)
Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine
ATP + Ubiquitin + Protein lysine <=> AMP + Diphosphate + Protein N-ubiquityllysine
2-Methylmaleate + H2O <=> D-threo-3-Methylmalate
Pantothenate + 2 Reduced acceptor <=> Pantothenol + 2 Acceptor + H2O
Glutaconyl-1-CoA + H2O <=> 2-Hydroxyglutaryl-CoA
N-Methyltyramine + S-Adenosyl-L-methionine <=> Hordenine + S-Adenosyl-L-homocysteine
3-Iodo-L-tyrosine + 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Triiodothyronine + Dehydroalanine + 2 H2O
Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Xanthurenic acid + S-Adenosyl-L-methionine <=> 8-Methoxykynurenate + S-Adenosyl-L-homocysteine
Hydroiodic acid + 3,5-Diiodo-L-tyrosine <=> 3-Iodo-L-tyrosine + Iodine
Aryl dialkyl phosphate + H2O <=> Dialkyl phosphate + Phenol
(R)-2-Methylmalate + CO2 <=> Parapyruvate + H2O
Galactosylceramide + UDP-alpha-D-galactose <=> Digalactosylceramide + UDP
N-Formiminoglycine <=> Imidazolone + H2O
2-Dehydro-D-glucose + Oxygen <=> 2-Dehydro-D-glucono-1,5-lactone + Hydrogen peroxide
2-Deoxy-D-gluconate + NAD+ <=> 3-Dehydro-2-deoxy-D-gluconate + NADH + H+
3-Phosphonopyruvate + L-Glutamate <=> 2-Amino-3-phosphonopropanoate + 2-Oxoglutarate
Imidazole-4-acetate:5-phosphoribosyl-diphosphate ligase (ADP- and pyrophosphate- forming)
3-Dehydrosphinganine + FAD <=> 3-Ketosphingosine + FADH2
3-Methylbutanoyl-CoA <=> Branched chain fatty acid
fatty acid,reduced-flaboprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Transferrin[Fe(II)]2 <=> Apotransferrin + 2 Fe2+
2-Oxohept-3-enedioate + H2O <=> 4-Hydroxy-2-oxo-heptanedioate
2-Oxohept-3-enedioate + H2O <=> 2,4-Dihydroxyhept-2-enedioate
5-Acetamidopentanoate + NADH + H+ + CO2 <=> 6-Acetamido-2-oxohexanoate + NAD+ + H2O
Transferrin[Fe(III)]2 <=> Apotransferrin + 2 Fe3+
(S)-4-Hydroxymandelate + Acceptor <=> 4-Hydroxyphenylglyoxylate + Reduced acceptor
3-Hydroxy-L-kynurenine <=> 3-Hydroxykynurenamine + CO2
6-Amino-2-oxohexanoate <=> Delta1-Piperideine-2-carboxylate + H2O
N-Formimino-L-aspartate <=> 4-Imidazolone-5-acetate + H2O
gamma-Oxalocrotonate + H2O <=> 4-Hydroxy-2-oxopentanoate + CO2
(S)-3-Methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)
2-Aminoethylphosphonate + Hydrogen peroxide <=> Ethanolamine + Orthophosphate
n (R)-3-Hydroxybutanoyl-CoA <=> Poly-beta-hydroxybutyrate + n CoA
4-Chlorocatechol + Oxygen <=> 3-Chloro-cis,cis-muconate
L-threo-3-Methylaspartate + 2-Oxoglutarate <=> Methyloxaloacetate + L-Glutamate
4-Imidazolone-5-propanoate + H2O <=> Formylisoglutamine
4-Imidazolone-5-propanoate + H2O <=> 4-Oxoglutaramate + Formate + Ammonia
Quinolinate + H2O <=> 2-Amino-3-carboxymuconate semialdehyde
(Z)-4-Hydroxyphenylacetaldehyde oxime <=> 4-Hydroxyphenylacetonitrile + H2O
N6,N6,N6-Trimethyl-L-lysine + 2 Protein <=> Protein N6,N6,N6-trimethyl-L-lysine + 2 H2O
Benzylpenicilloic acid <=> Penicillin G + H2O
5'-Phosphoribosylglycinamide + 5,10-Methenyltetrahydrofolate + H2O <=> 5'-Phosphoribosyl-N-formylglycinamide + Tetrahydrofolate
Lathosterol + CO2 + 4 H2O + 3 NADP+ <=> Methostenol + 3 Oxygen + 3 NADPH + 3 H+
L-2-Amino-6-oxoheptanedioate <=> 2,3,4,5-Tetrahydrodipicolinate + H2O
trans-5-O-(4-coumaroyl)-D-quinate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
1-Alkyl-sn-glycero-3-phosphate + NADP+ <=> O-Alkylglycerone phosphate + NADPH + H+
linalool,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
2-Dehydro-3-deoxy-D-xylonate + NAD+ <=> 5-Hydroxy-2,4-dioxopentanoate + NADH
4-Carboxy-4-hydroxy-2-oxoadipate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate + H2O
(S)-tetrahydrocolumbamine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming)
protein N6-(4-Aminobutyl)-L-lysine, hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)
L-1-Pyrroline-3-hydroxy-5-carboxylate + H2O <=> L-4-Hydroxyglutamate semialdehyde
1-Pyrroline-4-hydroxy-2-carboxylate + H2O <=> 2-Oxo-4-hydroxy-5-aminovalerate
1-Pyrroline-4-hydroxy-2-carboxylate <=> Pyrrole-2-carboxylate + H2O
N-hydroxy-L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
N6-Acetyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Acetyl-L-2-amino-6-oxopimelate + L-Glutamate
1-(5-Phosphoribosyl)imidazole-4-acetate + H2O <=> (1-Ribosylimidazole)-4-acetate + Orthophosphate
4-Carboxy-2-hydroxymuconate semialdehyde + H2O <=> 4-Methylene-2-oxoglutarate + Formate
2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <=> cis-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid
1-Phosphatidyl-1D-myo-inositol 3-phosphate + 2 ATP <=> Phosphatidylinositol-3,4,5-trisphosphate + 2 ADP
(4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + H2O <=> L-Xylonate + CO2
Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + FAD <=> (24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + FADH2
Biotin:apo-[acetyl-CoA:carbondioxide ligase (ADP-forming)] ligase (AMP-forming)
UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase
ATP:dephopho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] phopshotransferase
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA + FAD <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + FADH2
3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate <=> 5-Pyridoxolactone + H2O
N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H2O <=> alpha-Ribazole + Orthophosphate
Biotin:apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming)
20-OH-Leukotriene B4 <=> 20-COOH-Leukotriene B4
7,8-Dihydroneopterin + Orthophosphate <=> Dihydroneopterin phosphate + H2O
7,8-Dihydroneopterin + Acceptor <=> Neopterin + Reduced acceptor
CMP-N-acetylneuraminate + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GD2
N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> GA2 + N-Acetylneuraminate
1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + UDP-alpha-D-galactose <=> Ceramidepentasaccharide + UDP
1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + UDP-N-acetyl-D-galactosamine <=> Ceramidepentasaccharide + UDP
1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + GDP-L-fucose <=> Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + GDP
CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GD1b
D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + N-Acetylneuraminate <=> N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O
UDP-N-acetyl-D-glucosamine:glycoprotein (N-acetyl-D-glucosamine to alpha-D-mannosyl-1,6-(R1)-beta-D-mannosyl-R2) beta-1,2-N-acetyl-D-glucosaminyltransferase
CMP-N-acetylneuraminate + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide
CMP-N-acetylneuraminate + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GT1b
7-Dehydrodesmosterol + Reduced acceptor <=> 5alpha-Cholesta-7,24-dien-3beta-ol + Acceptor
24,25-Dihydrolanosterol + NADPH <=> 4alpha-Methylcholesta-8-en-3beta-ol + NADP+
Aminoacyl-tRNA + Phosphatidylglycerol <=> Aminoacyl-phosphatidylglycerol + tRNA
(S)-cheilanthifoline,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming)
Stylopine + S-Adenosyl-L-methionine <=> (S)-cis-N-Methylstylopine + S-Adenosyl-L-homocysteine
(S)-N-methylcoclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-O phenol-coupling)
(R)-reticuline,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-C phenol-coupling)
protopine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating)
(S)-cis-N-Methylstylopine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-hydroxylating)
6-Hydroxyprotopine <=> Dihydrosanguinarine + 2 H2O
dihydrosanguinarine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (10-hydroxylating)
dihydrochelirubine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
S-Adenosyl-L-methionine + Histone L-arginine <=> S-Adenosyl-L-homocysteine + Histone N(omega)-methyl-L-arginine
S-Adenosyl-L-methionine + [Myeline basic protein] L-arginine <=> S-Adenosyl-L-homocysteine + [Myeline basic protein] N(omega)-methyl-L-arginine
5-Aminoimidazole + CO2 <=> 5-Amino-4-imidazole carboxylate
7alpha-Hydroxytestosterone + Acceptor <=> 7alpha-Hydroxyandrost-4-ene-3,17-dione + Reduced acceptor
Desmosterol + S-Adenosyl-L-methionine <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + S-Adenosyl-L-homocysteine
2-Hydroxyestradiol + S-Adenosyl-L-methionine <=> 2-Methoxy-17beta-estradiol + S-Adenosyl-L-homocysteine
salutaridinol 7-O-acetate acetate-lyase (thebaine forming)
L-Selenomethionine <=> Selenohomocysteine + Activated methyl group
4-Hydroxyphenylacetyl-CoA + Glycine <=> p-Hydroxyphenylacetylglycine + CoA
(4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + H2O <=> L-Lyxonate + CO2
5-Cholestene + Oxygen + NADPH + H+ <=> 5,6beta-Epoxy-5beta-cholestane + NADP+ + H2O
5-Cholestene + NADPH + Oxygen + H+ <=> 5,6alpha-Epoxy-5alpha-cholestane + NADP+ + H2O
5,6beta-Epoxy-5beta-cholestane + H2O <=> 5alpha-Cholestan-5alpha,6beta-diol
5,6alpha-Epoxy-5alpha-cholestane + H2O <=> 5alpha-Cholestan-5alpha,6beta-diol
Phytyl diphosphate + Chlorophyllide <=> Bacteriopheophytin + Magnesium cation + Diphosphate
all-trans-zeta-Carotene + 2 Oxygen + 2 Reduced acceptor <=> Lycopene + 4 H2O + 2 Acceptor
beta-Zeacarotene + Oxygen + Reduced acceptor <=> gamma-Carotene + 2 H2O + Acceptor
3alpha,7alpha,26-Trihydroxy-5beta-cholestane + NAD+ <=> 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + NADH + H+
3alpha,7alpha-Dihydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + H2O + 2 Oxidized adrenal ferredoxin
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane + H2O + 2 Oxidized adrenal ferredoxin
7alpha-hydroxycholest-4-en-3-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating)
5-Ureido-4-imidazole carboxylate + H2O <=> 5-Amino-4-imidazole carboxylate + Ammonia + CO2
S-Glutathionyl-L-cysteine + Sulfate <=> S-Sulfo-L-cysteine + Glutathione
3-Sulfinylpyruvate + H2O <=> Sulfite + Pyruvate
Biocytin + 2 Peptide <=> Holo-[carboxylase] + 2 H2O
delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine + Oxygen <=> Isopenicillin N + 2 H2O
Imidazol-5-yl-pyruvate <=> Imidazole-4-acetaldehyde + CO2
Hydantoin-5-propionate + H2O <=> N-Carbamyl-L-glutamate
Imidazol-5-yl-pyruvate + NADH + H+ <=> Imidazole lactate + NAD+
Ergothioneine <=> Thiourocanic acid + Trimethylamine
Formylisoglutamine + H2O <=> Isoglutamine
5,6-Dihydroxyindole + CO2 <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
Indole-5,6-quinone + Oxygen <=> Eumelanin + H2O
2-Hydroxyhepta-2,4-dienedioate + H2O <=> 4-Hydroxy-2-oxo-heptanedioate
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate + NADPH + H+ <=> 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate + NADP+
4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate <=> 6-Hydroxykynurenate + H2O
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + NAD+ + H2O <=> 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate + NADH + H+
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + NADP+ + H2O <=> 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate + NADPH + H+
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + CO2 <=> 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate
CMP-2-aminoethylphosphonate + N-Acylsphingosine <=> Ceramide 2-aminoethylphosphonate + CMP
L-Selenocysteine <=> Selenocysteine seleninic acid
Pentosan + H2O <=> Pentosan + L-Arabinose
R + Se-Adenosylselenomethionine <=> CH3-R + Se-Adenosyl-L-selenohomocysteine
3'-Phosphoadenylylselenate + NADPH <=> Adenosine 3',5'-bisphosphate + Selenite + NADP+ + H+
N-Hydroxy-amino acid + Acceptor <=> 2-Oxoacid oxime + Reduced acceptor
R-S-Cysteinylglycine + H2O <=> S-Substituted L-cysteine + Glycine
Uroporphyrinogen I + Reduced acceptor <=> Uroporphyrin I + Acceptor + 6 H+
Coproporphyrinogen I + Acceptor <=> Coproporphyrin I + Reduced acceptor + 6 H+
Cobyrinate + 1-Aminopropan-2-ol + 6 Ammonia <=> Cobinamide + 7 H2O
2-Hexaprenylphenol + Oxygen + NADPH <=> 2-Hexaprenyl-6-hydroxyphenol + NADP+ + H2O
2-Hexaprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Hexaprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine
2-Octaprenylphenol + Oxygen + NADPH + H+ <=> 2-Octaprenyl-6-hydroxyphenol + NADP+ + H2O
cis-2-Hydroxycinnamate <=> Coumarin + H2O
(alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol + Dolichyl phosphate D-mannose <=> (alpha-D-Mannosyl)9-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol + Dolichyl phosphate
(3Z)-Phycocyanobilin + Acceptor <=> (3Z)-Phytochromobilin + Reduced acceptor + 2 H+
Leukotriene D4 + H2O <=> Leukotriene E4 + Glycine
Prostaglandin J2 <=> Delta-12-Prostaglandin J2
6-Keto-prostaglandin F1alpha + Acceptor <=> 6-Keto-prostaglandin E1 + Reduced acceptor
Thromboxane B2 + Acceptor <=> 11-Dehydro-thromboxane B2 + Reduced acceptor
2-Propylmalate + CoA <=> 2-Oxopentanoic acid + Acetyl-CoA + H2O
Parapyruvate + Ammonia <=> 4-Hydroxy-4-methylglutamate + H2O
Parapyruvate <=> 4-Methylene-2-oxoglutarate + H2O
4-Methylene-2-oxoglutarate + Ammonia <=> 4-Methyl-L-glutamate + H2O
Trigalactosyl-diacylglycerol + UDP <=> Digalactosyl-diacylglycerol + UDP-alpha-D-galactose
4-Hydroxy-L-threonine <=> 3-Aminopropane-1,2-diol + CO2
Ceramidepentasaccharide + GDP-L-fucose <=> Type A glycolipid + GDP
Gal-alpha1->3(Fuc-alpha1->2)Gal-beta1->3GlcNAc-beta1->3LacCer + UDP <=> Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + UDP-alpha-D-galactose
Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + UDP-N-acetyl-D-galactosamine <=> Type A glycolipid + UDP
UDP-alpha-D-galactose + GD2 <=> UDP + GD1b
UDP-alpha-D-galactose + GA2 <=> UDP + GA1
CMP-N-acetylneuraminate + GT1a <=> CMP + GQ1
CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1
CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b
GT1b + H2O <=> GD1b + N-Acetylneuraminate
Poly-beta-hydroxybutyrate + H2O <=> Poly[(R)-3-hydroxybutanoate]x + (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate
3-Butyn-1-al + NAD+ + H2O <=> 3-Butynoate + NADH + H+
3-Butyn-1-al + PQQ + H2O <=> 3-Butynoate + PQQH2
3-Butyn-1-al + PQQH2 <=> 3-Butyn-1-ol + PQQ
2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine + 2 S-Adenosyl-L-methionine <=> 6-(3'-Triphosphoryl-1'-methylglyceryl)-7-methyl-7,8-dihydrobiopterin + 2 S-Adenosyl-L-homocysteine + H2O
Anabasine + CO2 <=> Piperideine + Nicotinate
Piperideine + Acetoacetyl-CoA + H2O <=> Pelletierine + CoA + CO2
Piperideine + Pelletierine <=> L-(+)-Anaferine
2-aminobenzenesulfonate, NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)
acyl-CoA:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)
acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)
acyl-CoA:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing)
n ATP + Calmodulin + n Ubiquitin <=> n AMP + n Diphosphate + (Ubiquitin)n-calmodulin
Leukotriene E4 + L-Glutamate <=> Leukotriene F4 + H2O
(S)-coclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-O phenol-coupling)
(R)-N-methylcoclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-O phenol-coupling)
Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine <=> Precorrin 5 + S-Adenosyl-L-methionine + H2O
Adenosyl cobinamide + ATP <=> Adenosyl cobinamide phosphate + ADP
Cobamide coenzyme + GMP <=> Adenosine-GDP-cobinamide + alpha-Ribazole
Hydrogenobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Hydrogenobyrinate a,c diamide + 2 Orthophosphate + 2 L-Glutamate + 2 ADP
Adenosyl cobyrinate a,c diamide + 4 L-Glutamine + 4 ATP + 4 H2O <=> Adenosyl cobyrinate hexaamide + 4 L-Glutamate + 4 Orthophosphate + 4 ADP
Deacetylcephalosporin C + Succinate + CO2 <=> Deacetoxycephalosporin C + 2-Oxoglutarate + Oxygen
Deacetylcephalosporin C + Carbamoyl phosphate <=> O-Carbamoyl-deacetylcephalosporin C + Orthophosphate
trans-3-Chloroallyl aldehyde + H2O <=> trans-3-Chloroacrylic acid + 2 H+
cis-3-Chloroallyl aldehyde + H2O <=> cis-3-Chloroacrylic acid + 2 H+
Hydroquinone + Oxygen <=> cis,cis-4-Hydroxymuconic semialdehyde
2,3-Dihydroxy-p-cumate + Oxygen <=> 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate
1,2,3-Trihydroxybenzene + NADP+ + H2O <=> Resorcinol + Oxygen + NADPH + H+
2,2-Bis(4'-chlorophenyl)ethanol + H2O <=> Bis(4'-chlorophenyl)acetate + 4 H+
4-Chlorobenzoate <=> 4-Chlorobenzaldehyde + H2O
1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Reduced acceptor + 2 H+ <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethane + Acceptor
1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene + Oxygen <=> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate
2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + Oxygen <=> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate
DDT + Reduced acceptor + Oxygen <=> cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + Acceptor
4-Chlorobiphenyl + Oxygen + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NADP+
4-Nitrocatechol + Oxygen + 3 H+ <=> Benzene-1,2,4-triol + Nitrite + H2O
Hydrochloric acid + Hydroquinone + Glutathione disulfide <=> Chlorohydroquinone + 2 Glutathione
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + H+ <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Cl-
2,5-Dichlorohydroquinone + 2 Glutathione <=> Chlorohydroquinone + Glutathione disulfide + Hydrochloric acid
4-Aminobenzenesulfonate + 4-Aminobenzoate <=> 4-Carboxy-4'-sulfoazobenzene + 4 H+
4-Sulfocatechol + Oxygen <=> 3-Sulfomuconate
4-Aminobenzenesulfonate + Oxygen + 2 H+ <=> 4-Sulfocatechol + Ammonia
3,4-Dihydroxybenzoate + Ammonia <=> 4-Aminobenzoate + Oxygen + 2 H+
Toluene-4-sulfonate + Oxygen + NADH + H+ <=> 4-Sulfobenzyl alcohol + NAD+ + H2O
Toluate + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD+
Toluate + Oxygen + NADPH + H+ <=> cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+
(4E)-2-Oxohexenoic acid + H2O <=> 4-Hydroxy-2-oxohexanoic acid
O-Carbamoyl-deacetylcephalosporin C + 2-Oxoglutarate + Oxygen <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + Succinate + CO2
Cephamycin C + S-Adenosyl-L-homocysteine <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + S-Adenosyl-L-methionine
Nucleoside + Deoxynucleoside 5'-phosphate <=> Deoxynucleoside + Nucleoside 3'-phosphate
n-tetradecanoyl-CoA, NADPH2:O2 oxidoreductase [11-(E) desaturating]
n-tetradecanoyl-CoA, NADH:O2 oxidoreductase [11-(Z) desaturating]
n UDP-N-acetyl-alpha-D-glucosamine + n UDP-glucuronate <=> Hyaluronate + 2n UDP
N-Methylputrescine + Oxygen + H2O <=> 4-Methylaminobutanal + Hydrogen peroxide + Ammonia
4-Methylaminobutanal <=> 1-Methylpyrrolinium + H2O
4-Chloroacetophenone <=> 4-Chlorobenzaldehyde + CO2
Parathion + 3 Reduced acceptor <=> Aminoparathion + 3 Acceptor + 2 H2O
3-Methylbenzyl alcohol + NAD+ <=> 3-Methylbenzaldehyde + NADH + H+
2-Methylbenzyl alcohol + NAD+ <=> 2-Methylbenzaldehyde + NADH + H+
Fluoren-9-ol + NAD+ <=> Fluoren-9-one + NADH + H+
Fluoren-9-ol + NADP+ <=> Fluoren-9-one + NADPH + H+
Ethylene oxide + CoA + NAD+ <=> Acetyl-CoA + NADH + H+
2-Chloromaleylacetate + NADH <=> 2-Maleylacetate + NAD+ + Cl-
2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate + H2O <=> Salicylate + 2-Hydroxy-2,4-pentadienoate
2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate + H2O <=> 2-Hydroxymuconate + Catechol
6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate + H2O <=> 2-(4'-Chlorophenyl)-3,3-dichloropropenoate + 2-Hydroxy-3-chloropenta-2,4-dienoate
2,4,5-Trichloro-2,5-cyclohexadiene-1-ol + H2O <=> 2,5-Dichloro-2,5-cyclohexadiene-1,4-diol + Hydrochloric acid
Bis(4'-chlorophenyl)methane + CO2 <=> Bis(4'-chlorophenyl)acetate
2-Deoxy-5-keto-D-gluconic acid 6-phosphate Dihydroxyacetone phosphate-lyase
3-Chloro-cis,cis-muconate <=> Protoanemonin + Hydrochloric acid + CO2
3-Chloro-cis,cis-muconate <=> cis-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid
trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid <=> 2,5-Dichloro-cis,cis-muconate
2,4-Dichloro-cis,cis-muconate <=> trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid
cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NAD+ <=> 2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADH + H+
cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADP+ <=> 2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADPH + H+
1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + 2 H+ + 2 e- <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethane
3-Vinylcatechol + Oxygen <=> 2-Hydroxy-6-oxoocta-2,4,7-trienoate
3,5-Dichlorocatechol + Oxygen <=> 2,4-Dichloro-cis,cis-muconate
2,6-Dichlorohydroquinone + Oxygen + H2O <=> 2-Chloromaleylacetate + Hydrochloric acid
3,6-Dichlorocatechol + Oxygen <=> 2,5-Dichloro-cis,cis-muconate
3,4-Dihydroxyfluorene + Oxygen <=> 2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid
2,2',3-Trihydroxybiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate
1,2-Dihydroxyfluorene + Oxygen <=> 2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid
2,2',3-Trihydroxydiphenylether + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate
2'-Aminobiphenyl-2,3-diol + Oxygen <=> 2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate
3-Ethylcatechol + Oxygen <=> 2-Hydroxy-6-oxo-octa-2,4-dienoate + H+
Styrene + Oxygen + NADH + H+ <=> Styrene-cis-2,3-dihydrodiol + NAD+
2,4,5-Trichlorophenoxyacetic acid + Oxygen + NADH + H+ <=> 2,4,5-Trichlorophenol + Glyoxylate + NAD+ + H2O
2,4-Dichlorophenoxyacetate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Glyoxylate + Succinate + CO2
Parathion + H2O <=> Diethylthiophosphoric acid + 4-Nitrophenol
Fluorene + Oxygen + NADH + H+ <=> (+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene + NAD+
Ethylbenzene + Oxygen + NADH + H+ <=> (S)-1-Phenylethanol + NAD+ + H2O
(S)-1-Phenylethanol + Oxygen + NADH + H+ <=> Acetophenone + NAD+ + 2 H2O
2 Acetophenone + Oxygen <=> 2 2-Hydroxyacetophenone
o-Toluate + Oxygen + NADH + H+ <=> 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+
2 Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 Dihydrocoumarin + 2 NAD+
2 Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 3-Hydroxy-1-indanone + 2 NAD+
2 Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 Dihydrocoumarin + 2 NADP+
2 Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 3-Hydroxy-1-indanone + 2 NADP+
Dibenzofuran + Oxygen + NADH + H+ <=> 2,2',3-Trihydroxybiphenyl + NAD+
Fluoren-9-one + Oxygen + 2 NADH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NAD+
Fluoren-9-one + Oxygen + 2 NADPH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NADP+
2 2-Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 3-Isochromanone + 2 NAD+
2 2-Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 3-Isochromanone + 2 NADP+
Dibenzo-p-dioxin + Oxygen + NADH + H+ <=> 2,2',3-Trihydroxydiphenylether + NAD+
Ethylbenzene + Oxygen + NADH + H+ <=> cis-1,2-Dihydro-3-ethylcatechol + NAD+
Ethylene + Oxygen + NADH + H+ <=> Ethylene oxide + NAD+ + H2O
2,6-Dichlorohydroquinone + H2O <=> 6-Chlorobenzene-1,2,4-triol + Hydrochloric acid
2,5-Dichlorohydroquinone + FADH2 + Oxygen <=> 5-Chloro-2-hydroxy-p-benzoquinone + FAD + H2O + Cl-
2,4,5-Trichlorophenol + FADH2 + Oxygen <=> 2,5-Dichloro-p-benzoquinone + FAD + H2O + Cl-
2,6-Dichlorophenol + Oxygen + NADH + H+ <=> 2,6-Dichlorohydroquinone + NAD+ + H2O
2-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> Homogentisate + NAD+ + H2O
2-Succinylbenzoate <=> Spirodilactone + H2O
2-Succinylbenzoyl-CoA <=> Spirodilactone + CoA
D-Glyceraldehyde 3-phosphate + L-Arginine <=> L-N2-(2-Carboxyethyl)arginine + Orthophosphate
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + NADH + H+ + Oxygen <=> cis-3-[2,2-Dichloro-1-(4-chlorophenyl)vinyl]-6-chlorocyclohexa-3,5-diene-1,2-diol + NAD+
1-Chloro-2,2-bis(4'-chlorophenyl)ethane + H2O <=> 2,2-Bis(4'-chlorophenyl)ethanol + Hydrochloric acid
2,2-Bis(4'-chlorophenyl)ethanol <=> unsym-Bis(4'-chlorophenyl)ethylene + H2O
Bis(4'-chlorophenyl)acetate <=> 2,2-Bis(4'-chlorophenyl)ethanol + H2O
Hydroquinone + Nitrite + 7 H+ + 6 e- <=> 4-Hydroxyaniline + 3 H2O
1,2,4-Trichlorobenzene + Hydrochloric acid <=> 1,3,4,6-Tetrachloro-1,4-cyclohexadiene
2,4,5-Trichloro-2,5-cyclohexadiene-1-ol <=> 2,5-Dichlorophenol + Hydrochloric acid
Aminoparathion + H2O <=> Diethylthiophosphoric acid + 4-Hydroxyaniline
Diethylthiophosphoric acid + H2O <=> Diethylphosphoric acid + Hydrogen sulfide
phenylacetate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating)
DDT + Oxygen <=> cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane
4-Chlorophenoxyacetate + 2-Oxoglutarate + Oxygen <=> 4-Chlorophenol + Glyoxylate + Succinate + CO2
Ethylbenzene + H2O <=> 1-Phenylethanol + 2 H+
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Cl-
Vinyl chloride + 2 H+ <=> Ethylene + Hydrochloric acid
Tetrachloroethene + 2 H+ <=> Trichloroethene + Hydrochloric acid
Trichloroethene + 2 H+ <=> trans-1,2-Dichloroethene + Hydrochloric acid
Trichloroethene + 2 H+ <=> cis-1,2-Dichloroethene + Hydrochloric acid
trans-1,2-Dichloroethene + 2 H+ <=> Vinyl chloride + Hydrochloric acid
cis-1,2-Dichloroethene + 2 H+ <=> Vinyl chloride + Hydrochloric acid
5-Chloro-2-hydroxymuconic semialdehyde + H+ <=> 2-Hydroxymuconate semialdehyde + Cl-
2,4-Dichlorophenoxyacetate + H+ + 2 e- <=> 4-Chlorophenoxyacetate + Cl-
Benzoylacetyl-CoA + CoA <=> Benzoyl-CoA + Acetyl-CoA
Lactoyl-CoA + Acetate <=> (S)-Lactate + Acetyl-CoA
Acetyl-CoA + Acrylic acid <=> Acetate + Propenoyl-CoA
cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + H2O <=> 2-Chloromaleylacetate
D-Glucose 1-phosphate + Nucleoside triphosphate + Amino group donor + Activated methyl group <=> NDP-N-methyl-L-glucosamine + Orthophosphate
Streptomycin 6-phosphate + NADH + H+ <=> Dihydrostreptomycin 6-phosphate + NAD+
Erythromycin + Oxygen <=> Erythromycin E + H2O
beta-1,2,3,4,5,6-Hexachlorocyclohexane <=> delta-3,4,5,6-Tetrachlorocyclohexene + 2 Cl-
delta-3,4,5,6-Tetrachlorocyclohexene <=> 5,6-Dichloro-1,3-cyclohexadiene + 2 Cl-
5,6-Dichloro-1,3-cyclohexadiene <=> Chlorobenzene + Cl- + H+
5,6-Dichloro-1,3-cyclohexadiene <=> Benzene + 2 Cl-
3-(2-Hydroxyphenyl)propanoate + ATP + CoA + FAD + NAD+ <=> Salicylate + AMP + Diphosphate + FADH2 + Acetyl-CoA + NADH + H+
2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid + H2O <=> 2-Formyl-1-indanone + Pyruvate
2 Indanone + 2 CO2 <=> 2 2-Formyl-1-indanone + Oxygen
Fluorene + Oxygen + 2 H+ <=> 3,4-Dihydroxyfluorene
Fluorene + Oxygen + 2 H+ <=> 1,2-Dihydroxyfluorene
3,4-Dihydroxy-3,4-dihydro-9-fluorenone <=> 4-Hydroxy-9-fluorenone + H2O
2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid + H2O <=> 1-Formyl-2-indanone + Pyruvate
1-Formyl-2-indanone + H2O <=> 2-Indanone + CO2 + 2 H+ + 2 e-
2-Amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 H2O <=> 1,4-Cyclohexanedione + Ammonia + CO2 + CoA
N1-Amidinostreptamine 6-phosphate + L-Arginine <=> Streptidine 6-phosphate + L-Ornithine
Paraoxon + H2O <=> Diethylphosphoric acid + 4-Nitrophenol
D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose
Acrylic acid + Ammonia <=> Acrylamide + H2O
Chorismate + Ammonia <=> 4-Amino-4-deoxychorismate + H2O
Farnesyl diphosphate:Isopentenyl diphosphate farnesyl cistransferase
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 10-55 isopentenyl units)
2 Atrazine + Oxygen <=> 2 Deisopropylatrazine + 2 Acetone
2 Atrazine + Oxygen <=> 2 Deethylatrazine + 2 Acetaldehyde
2 Deisopropylatrazine + Oxygen <=> 2 Deisopropyldeethylatrazine + 2 Acetaldehyde
2 Deethylatrazine + Oxygen <=> 2 Deisopropyldeethylatrazine + 2 Acetone
Deisopropyldeethylatrazine + H2O <=> 2-Chloro-4-hydroxy-6-amino-1,3,5-triazine + Ammonia
Deisopropylatrazine + H2O <=> Deisopropylhydroxyatrazine + Hydrochloric acid
2-Hydroxycyclohexane-1-carboxyl-CoA + NAD+ <=> 2-Ketocyclohexane-1-carboxyl-CoA + NADH + H+
2,6-Dihydroxycyclohexane-1-carboxyl-CoA + Acceptor <=> 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA + Reduced acceptor
Anthraniloyl-CoA + 2 H+ <=> Benzoyl-CoA + Ammonia
3-Oxopimeloyl-CoA + CoA <=> Glutaryl-CoA + Acetyl-CoA
Benzoylsuccinyl-CoA + CoA <=> Benzoyl-CoA + Succinyl-CoA
Benzylsuccinate + Succinyl-CoA <=> Benzylsuccinyl-CoA + Succinate
2-Ketocyclohexane-1-carboxyl-CoA + H2O <=> 6-Carboxyhexanoyl-CoA
Crotonoyl-CoA + H2O <=> 3-Hydroxybutanoyl-CoA
E-Phenylitaconyl-CoA + H2O <=> (Hydroxymethylphenyl)succinyl-CoA
Cyclohex-1-ene-1-carboxyl-CoA + H2O <=> 2-Hydroxycyclohexane-1-carboxyl-CoA
6-Carboxyhex-2-enoyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2,6-Dihydroxycyclohexane-1-carboxyl-CoA
Phenolic phosphate + CO2 + H2O <=> 4-Hydroxybenzoate + Orthophosphate
all-trans-Octaprenyl diphosphate + Diphosphate <=> all-trans-Heptaprenyl diphosphate + Isopentenyl diphosphate
all-trans-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + Diphosphate
all-trans-Pentaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + Diphosphate
Cyclohexane-1-carboxyl-CoA + Acceptor <=> Cyclohex-1-ene-1-carboxyl-CoA + Reduced acceptor
Cyclohexane-1-carboxylate + CoA + ATP <=> Cyclohexane-1-carboxyl-CoA + AMP + Diphosphate
Benzoate + NADH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
Benzoate + NADPH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NADP+
lanosterol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving)
cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O <=> 1-Hydroxy-2-naphthaldehyde + Pyruvate
1-Hydroxy-2-naphthaldehyde + NAD+ + H2O <=> 1-Hydroxy-2-naphthoate + NADH + H+
Phenanthrene-3,4-diol + Oxygen <=> 2-Hydroxy-2H-benzo[h]chromene-2-carboxylate
acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming)
Phenanthrene + Oxygen + NADH + H+ <=> 1-Phenanthrol + H2O + NAD+
1-Phenanthrol + CH3-R <=> 1-Methoxyphenanthrene + R
Phenanthrene-9,10-oxide + H2O <=> trans-9(S),10(S)-Dihydrodiolphenanthrene
2,4,6/3,5-Pentahydroxycyclohexanone <=> D-2,3-Diketo 4-deoxy-epi-inositol + H2O
2-Methylbenzaldehyde + NADP+ + H2O <=> o-Toluate + NADPH + H+
3-Methylbenzaldehyde + NADP+ + H2O <=> m-Methylbenzoate + NADPH + H+
m-Methylbenzoate + NADH + Oxygen + H+ <=> 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+
ATP + NAD+ <=> 3'-Keto-3'-deoxy-ATP + NADH + H+
3'-Keto-3'-deoxy-ATP <=> 3'-Keto-3'-deoxy-AMP + Diphosphate
3'-Amino-3'-deoxy-AMP + L-Tyrosine <=> N6,N6,O-Tridemethylpuromycin-5'-phosphate
N6,N6,O-Tridemethylpuromycin-5'-phosphate + Acetyl-CoA <=> N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + CoA
N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine
N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-O-demethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine
N-Acetyl-O-demethylpuromycin + S-Adenosyl-L-methionine <=> N-Acetylpuromycin + S-Adenosyl-L-homocysteine
N-Acetylpuromycin + H2O <=> Puromycin + Acetate
(S)-3-Sulfolactate + NADP+ <=> 3-Sulfopyruvate + NADPH + H+
Adenosine + Oxygen <=> 5'-Dehydroadenosine + Hydrogen peroxide
5'-Dehydroadenosine + Oxygen + H2O <=> 9-Riburonosyladenine + Hydrogen peroxide
(E)-4-hydroxyphenylacetaldehyde oxime,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase
obtusifoliol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving)
(S)-N-methylcoclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine
Cobalt-precorrin 5 + S-Adenosyl-L-methionine + H2O <=> Cobalt-precorrin 6 + S-Adenosyl-L-homocysteine + Acetaldehyde
Cobalt-dihydro-precorrin 6 + 2 S-Adenosyl-L-methionine <=> Cobalt-precorrin 8 + 2 S-Adenosyl-L-homocysteine + CO2
10-deoxysarpagine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (10-hydroxylating)
Geissoschizine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Polyneuridine aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
7-deoxyloganate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7alpha-hydroxylating)
loganate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ring-cleaving)
3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + 2 H+ <=> Deoxycholic acid
Glycolaldehyde + 2-Oxobutanoate + Alanine <=> Pyridoxine
Phenanthrene + NADH + H+ + Oxygen <=> (+)-cis-3,4-Dihydrophenanthrene-3,4-diol + NAD+
Dialdehyde + H+ <=> 4,21-Dehydrocorynantheine aldehyde + H2O
Cathenamine + NADPH + H+ <=> Ajmalicine + NADP+
Cathenamine + NADPH + H+ <=> Tetrahydroalstonine + NADP+
Ajmalicine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Serpentine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O + 2 H+
tabersonine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (16-hydroxylating)
16-Methoxytabersonine + H2O <=> 16-Methoxy-2,3-dihydro-3-hydroxytabersonine
Vindoline + Catharanthine <=> 3',4'-Anhydrovinblastine
Tabersonine + NADPH + H+ + Oxygen <=> Lochnericine + NADP+ + H2O
Minovincinine + Acetyl-CoA <=> Echitovenine + CoA
19-epi-Cathenamine + NADPH + H+ <=> 19-epi-Ajmalicine + NADP+
vinorine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (21alpha-hydroxylating)
Norajmaline + S-Adenosyl-L-methionine <=> Ajmaline + S-Adenosyl-L-homocysteine
Protoemetine + Tryptamine <=> Deoxytubulosine
10-Deoxygeniposidic acid <=> Geniposidic acid
UDP-N-acetyl-D-glucosamine + G00025 <=> UDP + G00209
UDP-N-acetyl-D-glucosamine + Galactosylgloboside <=> UDP + G00102
UDP-D-galactose + G00102 <=> UDP + G00103
CMP-N-acetylneuraminate + G00393 <=> CMP + G00251
CMP-N-acetylneuraminate + G00837 <=> CMP + G00251
UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen
UDP-D-galactose + Tn antigen <=> UDP + T antigen
UDP-N-acetyl-D-glucosamine + Tn antigen <=> UDP + G00028
UDP-N-acetyl-D-glucosamine + Tn antigen <=> UDP + G00031
CMP-N-acetylneuraminate + Tn antigen <=> CMP + Sialyl-Tn antigen
UDP-N-acetyl-D-glucosamine + T antigen <=> UDP + G00025
CMP-N-acetylneuraminate + T antigen <=> CMP + G00026
CMP-N-acetylneuraminate + G00026 <=> CMP + G00027
UDP-N-acetyl-D-glucosamine + G00028 <=> UDP + G00029
UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143
Dolichyl phosphate D-mannose + G00145 <=> Dolichyl phosphate + G00146
Dolichyl phosphate D-mannose + G00148 <=> Dolichyl phosphate + G00149
Phosphatidylethanolamine + G00140 <=> 1,2-Diacyl-sn-glycerol + G00141
Phosphatidylethanolamine + G00141 <=> 1,2-Diacyl-sn-glycerol + G00151
UDP-D-xylose + [Protein]-L-serine <=> UDP + G00154
UDP-D-galactose + G00154 <=> UDP + G00155
UDP-D-galactose + G00155 <=> UDP + G00156
UDP-D-glucuronate + G00156 <=> UDP + G00157
UDP-N-acetyl-D-galactosamine + G00157 <=> UDP + G00158
UDP-N-acetyl-D-glucosamine + G00157 <=> UDP + G00162
UDP-D-glucuronate + G00158 <=> UDP + G00159
UDP-N-acetyl-D-galactosamine + G00159 <=> UDP + G00160
UDP-D-glucuronate + G00160 <=> UDP + G00180
UDP-N-acetyl-D-galactosamine + G00180 <=> UDP + G00161
UDP-D-glucuronate + G00162 <=> UDP + G00163
UDP-N-acetyl-D-glucosamine + G00163 <=> UDP + G00164
CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + GM3
UDP-N-acetyl-D-galactosamine + Lactosylceramide <=> UDP + GA2
UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + GM2
CMP-N-acetylneuraminate + GM3 <=> CMP + GD3
CMP-N-acetylneuraminate + GM1 <=> CMP + GD1a
CMP-N-acetylneuraminate + GD1a <=> CMP + GT1a
GDP-L-fucose + GM1 <=> GDP + Fucosyl-GM1
CMP-N-acetylneuraminate + GD1a <=> CMP + GT1aalpha
UDP-N-acetyl-D-galactosamine + GD3 <=> UDP + GD2
CMP-N-acetylneuraminate + GD3 <=> CMP + GT3
CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1b
CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1balpha
UDP-N-acetyl-D-galactosamine + GT3 <=> UDP + GT2
CMP-N-acetylneuraminate + GT1c <=> CMP + GQ1c
CMP-N-acetylneuraminate + GQ1c <=> CMP + GP1c
CMP-N-acetylneuraminate + GA1 <=> CMP + GM1b
CMP-N-acetylneuraminate + GM1b <=> CMP + GD1c
CMP-N-acetylneuraminate + GM1b <=> CMP + GD1a
UDP-D-galactose + Lactosylceramide <=> UDP + Globotriaosylceramide
H2O + Globotriaosylceramide <=> D-Galactose + Lactosylceramide
UDP-N-acetyl-D-galactosamine + Globotriaosylceramide <=> UDP + Globoside
H2O + Globoside <=> N-Acetyl-D-galactosamine + Globotriaosylceramide
UDP-D-galactose + Globoside <=> UDP + Galactosylgloboside
UDP-N-acetyl-D-galactosamine + Globoside <=> UDP + Forssman antigen, IV3GalNAca-Gb4Cer
H2O + Forssman antigen, IV3GalNAca-Gb4Cer <=> N-Acetyl-D-galactosamine + Globoside
CMP-N-acetylneuraminate + Galactosylgloboside <=> CMP + Monosialylgalactosylgloboside
GDP-L-fucose + Galactosylgloboside <=> GDP + Globo-H
UDP-N-acetyl-D-glucosamine + N-Acetyl-D-glucosaminyldiphosphodolichol <=> UDP + N,N'-Chitobiosyldiphosphodolichol
UDP-N-acetyl-D-glucosamine + Lactosylceramide <=> UDP + Lc3Cer
GDP-D-mannose + N,N'-Chitobiosyldiphosphodolichol <=> GDP + G00003
UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + nLc7Cer
UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + nLc5Cer
Protein asparagine + G00008 <=> Dolichyl diphosphate + G00009
UDP-D-galactose + Lc3Cer <=> UDP + Paragloboside
UDP-D-galactose + Paragloboside <=> UDP + nLc5Cer
UDP-N-acetyl-D-glucosamine + G00012 <=> UDP + G00013
UDP-N-acetyl-D-glucosamine + G00014 <=> UDP + G00015
UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G00019
UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G00020
UDP-N-acetyl-D-glucosamine + G00020 <=> UDP + G00021
UDP-N-acetyl-D-glucosamine + G00021 <=> UDP + G00022
CMP-N-acetylneuraminate + GT1a <=> CMP + GQ1b
GT1b + N-Acetylneuraminate <=> GQ1b + H2O
CMP-N-acetylneuraminate + GD1a <=> CMP + GT1b
GA2 + H2O <=> Lactosylceramide + N-Acetyl-D-galactosamine
CMP-N-acetylneuraminate + GA1 <=> CMP + GM1
GM2 + H2O <=> GM3 + N-Acetyl-D-galactosamine
CMP-N-acetylneuraminate + GM1 <=> CMP + GD1b
UDP-D-galactose + Lc3Cer <=> UDP + Lc4Cer
CMP-N-acetylneuraminate + GA2 <=> CMP + GM2
CMP-N-acetylneuraminate + GM2 <=> CMP + GD2
UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + G00176
UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + G00174
UDP-N-acetyl-D-glucosamine + G00172 <=> UDP + G07376
1,3-beta-D-Glucan(n) + Orthophosphate <=> 1,3-beta-D-Glucan(n-1) + D-Glucose 1-phosphate
1,3-beta-D-Glucan(n) + UDP-D-glucose <=> 1,3-beta-D-Glucan(n+1) + UDP
UDP-D-galactose + G00077 <=> UDP + iso-nLc8Cer
GDP-L-fucose + Paragloboside <=> GDP + IV2Fuc-nLc4Cer
GDP-L-fucose + Paragloboside <=> GDP + III3Fuc-nLc4Cer
CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-3-paragloboside
GDP-L-fucose + nLc5Cer <=> GDP + Type II B antigen
UDP-D-galactose + IV2Fuc-nLc4Cer <=> UDP + Type II B antigen
GDP-L-fucose + G00057 <=> GDP + Type IIIH glycolipid
CMP-N-acetylneuraminate + Sialyl-3-paragloboside <=> CMP + 3',8'-LD1
UDP-D-galactose + nLc5Cer <=> UDP + nLc6Cer
GDP-L-fucose + nLc6Cer <=> GDP + VI2Fuc-nLc6
CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI3NeuAc-nLc6Cer
GDP-L-fucose + nLc6Cer <=> GDP + V3Fuc-nLc6Cer
beta-D-Mannosylphosphodecaprenol + 1,6-alpha-D-Mannosyloligosaccharide <=> Decaprenol phosphate + 1,6-alpha-D-Mannosyl-1,6-alpha-D-mannosyloligosaccharide
UDP-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
3-Deoxyoctulosonyl-lipopolysaccharide + H2O <=> 3-Deoxy-D-manno-octulosonate + Lipopolysaccharide
UDP-D-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
5-Hydroxyisourate + H+ + H2O <=> (R)(-)-Allantoin + CO2
5-Hydroxyisourate + H+ + H2O <=> (S)-Allantoin + CO2
n UDP-N-acetyl-D-glucosamine + n UDP-D-glucuronate <=> Hyaluronic acid + 2n UDP
Raffinose + H2O <=> D-Galactose + Sucrose
Galactinol + Sucrose <=> myo-Inositol + Raffinose
beta-D-Mannosylphosphodecaprenol + 1,6-alpha-D-Mannosyloligosaccharide(n) <=> Decaprenol phosphate + 1,6-alpha-D-Mannosyloligosaccharide(n+1)
GDP-L-fucose + Sialyl-3-paragloboside <=> GDP + IV3NeuAc,III3Fuc-nLc4Cer
GDP-L-fucose + VI2Fuc-nLc6 <=> GDP + G00081
1,4-beta-D-Glucan(n+1) + H2O <=> 1,4-beta-D-Glucan(n) + beta-D-Glucose
1,3-beta-D-Glucan(n+1) + H2O <=> 1,3-beta-D-Glucan(n) + alpha-D-Glucose
Isomaltose + H2O <=> alpha-D-Glucose + D-Glucose
beta-1,4-Poly-N-acetyl-D-glucosamine(n+1) + H2O <=> N-Acetyl-D-glucosamine + beta-1,4-Poly-N-acetyl-D-glucosamine(n)
beta-1,4-Poly-N-acetyl-D-glucosamine(n+2) + H2O <=> Chitobiose + beta-1,4-Poly-N-acetyl-D-glucosamine(n)
Xylan(n) + UDP-D-xylose <=> Xylan(n+1) + UDP
GDP-L-fucose + iso-nLc8Cer <=> GDP + Monofucosyllactoisooctaosylceramide
GDP-L-fucose + Monofucosyllactoisooctaosylceramide <=> GDP + G00079
Sucrose + H2O <=> D-Fructose + D-Glucose
Sucrose + H2O <=> beta-D-Fructose + alpha-D-Glucose
Melibiose + H2O <=> D-Galactose + D-Glucose
Galactinol + H2O <=> myo-Inositol + D-Galactose
Galabiosylceramide + H2O <=> Galactosylceramide + D-Galactose
GDP-L-fucose + IV2Fuc-nLc4Cer <=> GDP + III3,IV2Fuc-nLc4Cer
Manninotriose + H2O <=> D-Galactose + Melibiose
UDP-D-galactose + nLc7Cer <=> UDP + nLc8Cer
Lactose + H2O <=> alpha-D-Glucose + D-Galactose
Lactosylceramide + H2O <=> Glucosylceramide + D-Galactose
Raffinose + H2O <=> Melibiose + D-Fructose
Stachyose + H2O <=> Manninotriose + D-Fructose
Sucrose 6'-phosphate + H2O <=> beta-D-Fructose + alpha-D-Glucose 6-phosphate
Cellotriose + H2O <=> Cellobiose + D-Glucose
Cellotetraose + H2O <=> Cellotriose + D-Glucose
Cellopentaose + H2O <=> Cellotetraose + D-Glucose
Celloheptaose + H2O <=> Cellohexaose + D-Glucose
Cellohexaose + H2O <=> Cellopentaose + D-Glucose
Lactose 6'-phosphate + H2O <=> beta-D-Glucose + D-Galactose 6-phosphate
G10518 + H2O <=> D-Glucose + D-Glucose 6-phosphate
H2O + Trehalose 6-phosphate <=> D-Glucose + D-Glucose 6-phosphate
Lactose + H2O <=> D-Glucose + D-Galactose
H2O + Maltose 6'-phosphate <=> D-Glucose + D-Glucose 6-phosphate
G10523 + H2O <=> 6-Deoxy-L-galactose + Methyl beta-D-galactoside
(R)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating)
alpha-Amino acid + H2O + Oxygen <=> 2-Oxo acid + Ammonia + Hydrogen peroxide
alpha-Amino acid <=> 2-Oxo acid + Ammonia
alpha-Amino acid <=> 2,3-Ene acid + Ammonia
T antigen + H2O <=> G10607 + [Protein]-L-serine
Chitobiose + H2O <=> 2 N-Acetyl-D-glucosamine
Epimelibiose + H2O <=> D-Mannose + D-Galactose
G10530 + H2O <=> N,6-O-Disulfo-D-glucosamine + D-Glucuronate
3-Ketolactose + H2O <=> 3-Keto-beta-D-galactose + beta-D-Glucose
N-Acetyllactosamine + UDP-D-galactose <=> Linear B type 2 trisaccharide + UDP
Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O
1,6-alpha-D-Mannosyloligosaccharide(n+1) + H2O <=> D-Mannose + G10542(n)
CMP-N-acetylneuraminate + Lc4Cer <=> CMP + 3'-isoLM1
GDP-L-fucose + Lc4Cer <=> GDP + Fuc-Lc4Cer
GDP-L-fucose + Lc4Cer <=> GDP + IV2Fuc-Lc4Cer
G10544 + H2O <=> Starch + N-Acylsphingosine
Starch + H2O <=> 1,4-alpha-D-Glucan + alpha-D-Glucose
Cyclomaltodextrin + H2O <=> 1,4-alpha-D-Glucan
Bis-D-fructose 2',1:2,1'-dianhydride + H2O <=> Inulobiose
GDP-L-fucose + Type IA glycolipid <=> GDP + G00043
GDP-L-fucose + IV2Fuc-Lc4Cer <=> GDP + IV2Fuc,III4Fuc-Lc4Cer
GDP-L-fucose + Type IB glycolipid <=> GDP + G00040
GDP-L-fucose + 3'-isoLM1 <=> GDP + Fuc-3'-isoLM1
UDP-N-acetyl-D-galactosamine + IV2Fuc-Lc4Cer <=> UDP + Type IA glycolipid
UDP-D-galactose + IV2Fuc-Lc4Cer <=> UDP + Type IB glycolipid
UDP-D-galactose + Lc4Cer <=> UDP + G00038
G10551 + UDP-N-acetyl-D-glucosamine <=> G10550 + UDP
G10552 + UDP-N-acetyl-D-glucosamine <=> G10553 + UDP
G10556 + UDP-N-acetyl-D-glucosamine <=> G10555 + UDP
Chitosan(n+m) + H2O <=> Chitosan(n) + Chitosan(m)
G10555 + G10557(n) <=> di-trans,poly-cis-Undecaprenyl diphosphate + G10557(n+1)
G10553 + G10554(n) <=> di-trans,poly-cis-Undecaprenyl diphosphate + G10554(n+1)
(R,R)-Tartaric acid + NAD+ <=> 2-Hydroxy-3-oxosuccinate + NADH + H+
Starch + Orthophosphate <=> 1,4-alpha-D-Glucan + D-Glucose 1-phosphate
UDP-N-acetyl-D-galactosamine + IV2Fuc-nLc4Cer <=> UDP + Type II A antigen
UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + G00077
UDP-D-galactose + VI2Fuc-nLc6 <=> UDP + G00083
UDP-N-acetyl-D-galactosamine + G00074 <=> UDP + Type IIIAb
UDP-D-galactose + G00072 <=> UDP + G00073
UDP-N-acetyl-D-galactosamine + VI2Fuc-nLc6 <=> UDP + G00072
UDP-N-acetyl-D-galactosamine + Type IIIH glycolipid <=> UDP + Type IIIA glycolipid
UDP-D-galactose + Type II A antigen <=> UDP + G00057
Starch(n+1) + H2O <=> alpha-D-Glucose + Starch(n)
1,4-beta-D-Glucan(n+2) + H2O <=> 1,4-beta-D-Glucan(n) + Cellobiose
Pectic acid(n+1) + H2O <=> D-Galacturonate + Pectic acid(n)
D-Xylose + Xylan(n) <=> Xylan(n+1) + H2O
1,3-beta-D-Glucan(n+1) + H2O <=> D-Glucose + 1,3-beta-D-Glucan(n)
Starch(n+m) + H2O <=> Starch(n) + Starch(m)
Sucrose 6'-phosphate + H2O <=> Sucrose + Orthophosphate
UDP-D-galactose + myo-Inositol <=> UDP + Galactinol
CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-6-paragloboside
CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI6NeuAc-nLc6Cer
GDP-L-fucose + V3Fuc-nLc6Cer <=> GDP + V3Fuc,III3Fuc-nLc6Cer
D-Glucosamine + Chitosan(n) <=> Chitosan(n+1) + H2O
UDP-D-glucose + alpha-D-Glucose 6-phosphate <=> UDP + Trehalose 6-phosphate
Trehalose 6-phosphate + H2O <=> Trehalose + Orthophosphate
Trehalose + Protein N(pi)-phospho-L-histidine <=> Trehalose 6-phosphate + Protein histidine
GDP-L-fucose + nLc6Cer <=> GDP + III3Fuc-nLc6Cer
CMP-N-acetylneuraminate + V3Fuc-nLc6Cer <=> CMP + G00091
Galactosylceramide + UDP-D-galactose <=> Galabiosylceramide + UDP
Protein N(pi)-phospho-L-histidine + Maltose <=> Protein histidine + Maltose 6'-phosphate
Protein N(pi)-phospho-L-histidine + Lactose <=> Protein histidine + Lactose 6'-phosphate
Pectic acid(n+2) + H2O <=> G02614 + Pectic acid(n)
Pectic acid(n+2) <=> G10113 + Pectic acid(n)
beta-1,4-Poly-N-acetyl-D-glucosamine + n H2O <=> Chitosan + n Acetate
Hyaluronic acid <=> n Hyaluronan-derived disaccharide
Cellobiose + Oxygen <=> G10590 + Hydrogen peroxide
Cellobiose + Acceptor <=> G10590 + Reduced acceptor
Cellobiose + Quinone <=> G10590 + Hydroquinone
Pectin + n H2O <=> n Methanol + Pectic acid
Acetyl-CoA + Maltose <=> CoA + Acetyl-maltose
GM1 + N-Acetylneuraminate <=> GD1a + H2O
2 I-Urobilinogen + Oxygen <=> 2 Urobilin + 2 H2O
2 L-Urobilinogen + Oxygen <=> 2 L-Urobilin + 2 H2O
D-Urobilinogen + 2 H+ <=> I-Urobilinogen
I-Urobilinogen + 4 H+ <=> L-Urobilinogen
Dolichyl phosphate D-mannose + G00006 <=> Dolichyl phosphate + G10595
Dolichyl phosphate D-mannose + G10595 <=> Dolichyl phosphate + G10596
Dolichyl phosphate D-mannose + G10596 <=> Dolichyl phosphate + G10597
Dolichyl phosphate D-mannose + G10597 <=> Dolichyl phosphate + G00007
magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)
magnesium-protoporphyrin-IX 13-monomethyl ester,S-adenosyl-L-methionine:H2O oxidoreductase (hydroxylating)
Divinylprotochlorophyllide + 2 H+ <=> Protochlorophyllide
CMP-N-acetylneuraminate + G04854 <=> CMP + G04461
CMP-N-acetylneuraminate + G04461 <=> CMP + G04135
UDP-D-glucose + N-Acylsphingosine <=> UDP + Glucosylceramide
Glucosylceramide + UDP-D-galactose <=> Lactosylceramide + UDP
UDP-D-galactose + N-Acylsphingosine <=> UDP + Galactosylceramide
n UDP-D-galacturonate <=> n UDP + Pectin
3'-Phosphoadenylyl sulfate + Galactosylceramide <=> Adenosine 3',5'-bisphosphate + Sulfatide
Sulfatide + H2O <=> Galactosylceramide + Sulfate
H2O + 3'-LM1-NeuGc <=> N-Acylsphingosine + nLc4
3-Deoxy-D-manno-octulosonyl-lipid IV(A) + CMP-3-deoxy-D-manno-octulosonate <=> Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) + CMP
Divinyl chlorophyllide a <=> Divinylchlorophyll a
ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
ent-Kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
ent-kaur-16-en-19-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene forming)
taxa-4(20),11-dien-5alpha-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (13alpha-hydroxylating)
taxa-4(20),11-dien-5alpha-yl acetate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (10beta-hydroxylating)
10beta,14beta-Dihydroxytaxa-4(20),11-dien-5alpha-yl acetate <=> 10-Deacetyl-2-debenzoylbaccatin III
Gibberellin A14 <=> Gibberellin A37 open lactone
Gibberellin A37 open lactone <=> Gibberellin A36
Gibberellin A36 <=> Gibberellin A4 + CO2
Gibberellin A12 aldehyde <=> Gibberellin A53 aldehyde
Gibberellin A15 open lactone <=> Gibberellin A44 diacid
Gibberellin A15 open lactone <=> Gibberellin A37 open lactone
Gibberellin A24 + 2-Oxoglutarate + Oxygen <=> Gibberellin A36 + Succinate + CO2
Gibberellin A14 aldehyde <=> Gibberellin A14
Gibberellin A53 aldehyde <=> Gibberellin A53
Gibberellin A12 aldehyde <=> Gibberellin A14 aldehyde
Gibberellin A9 <=> 2,3-Dehydro-gibberellin A9
2,3-Dehydro-gibberellin A9 <=> Gibberellin A7
abieta-7,13-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating)
abietinol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating)
O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate + NDP-N-methyl-L-glucosamine <=> Dihydrostreptomycin 6-phosphate + NDP
2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA + Acceptor <=> 4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA + Reduced acceptor
4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA + H2O <=> 3-Isopropenylpimelyl-CoA
dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+ <=> dTDP-L-olivose + NADP+
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose <=> Maltol + dTDP
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units)
5 Methylmalonyl-CoA + 2 Malonyl-CoA + (2S)-Ethylmalonyl-CoA + 7 NADPH + 7 H+ <=> 8 CoA + Tylactone + 8 CO2 + 3 H2O + 7 NADP+
5-O-beta-D-Mycaminosyltylactone + 2 NADPH + 2 Oxygen + 2 H+ <=> 20-Oxo-5-O-beta-mycaminosyltylactone + 2 NADP+ + 3 H2O
Malonyl-CoA + 6 Methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 8,8a-Deoxyoleandolide + 7 CoA + 7 CO2 + H2O + 6 NADP+
8,8a-Deoxyoleandolide + 2 NADPH + 2 H+ + 2 Oxygen <=> Oleandolide + 2 NADP+ + 3 H2O
Oleandolide + dTDP-L-olivose <=> L-Olivosyl-oleandolide + dTDP
L-Oleandrosyl-oleandolide + dTDP-D-desosamine <=> Oleandomycin + dTDP
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2a'' aglycone + NADP+ + H2O
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''1a'' aglycone + NADP+ + H2O
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2b'' aglycone + NADP+ + H2O
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''1b'' aglycone + NADP+ + H2O
5-Oxoavermectin ''2a'' aglycone + NADPH + H+ <=> Avermectin B2a aglycone + NADP+
5-Oxoavermectin ''1a'' aglycone + NADPH + H+ <=> Avermectin B1a aglycone + NADP+
5-Oxoavermectin ''2b'' aglycone + NADPH + H+ <=> Avermectin B2b aglycone + NADP+
5-Oxoavermectin ''1b'' aglycone + NADPH + H+ <=> Avermectin B1b aglycone + NADP+
Avermectin B2a aglycone + S-Adenosyl-L-methionine <=> Avermectin A2a aglycone + S-Adenosyl-L-homocysteine
Avermectin B1a aglycone + S-Adenosyl-L-methionine <=> Avermectin A1a aglycone + S-Adenosyl-L-homocysteine
Avermectin B2b aglycone + S-Adenosyl-L-methionine <=> Avermectin A2b aglycone + S-Adenosyl-L-homocysteine
Avermectin B1b aglycone + S-Adenosyl-L-methionine <=> Avermectin A1b aglycone + S-Adenosyl-L-homocysteine
2-Methylbutanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+
2-Methylbutanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1a'' aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+
2-Methylpropanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+
2-Methylpropanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1b'' aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+
Avermectin B2a aglycone + dTDP-L-oleandrose <=> Avermectin B2a monosaccharide + dTDP
Avermectin B2a monosaccharide + dTDP-L-oleandrose <=> Avermectin B2a + dTDP
Avermectin A2a aglycone + dTDP-L-oleandrose <=> Avermectin A2a monosaccharide + dTDP
Avermectin A2a monosaccharide + dTDP-L-oleandrose <=> Avermectin A2a + dTDP
Avermectin B1a aglycone + dTDP-L-oleandrose <=> Avermectin B1a monosaccharide + dTDP
Avermectin B1a monosaccharide + dTDP-L-oleandrose <=> Avermectin B1a + dTDP
Avermectin A1a aglycone + dTDP-L-oleandrose <=> Avermectin A1a monosaccharide + dTDP
Avermectin A1a monosaccharide + dTDP-L-oleandrose <=> Avermectin A1a + dTDP
Avermectin B2b aglycone + dTDP-L-oleandrose <=> Avermectin B2b monosaccharide + dTDP
Avermectin B2b monosaccharide + dTDP-L-oleandrose <=> Avermectin B2b + dTDP
Avermectin A2b aglycone + dTDP-L-oleandrose <=> Avermectin A2b monosaccharide + dTDP
Avermectin A2b monosaccharide + dTDP-L-oleandrose <=> Avermectin A2b + dTDP
Avermectin B1b aglycone + dTDP-L-oleandrose <=> Avermectin B1b monosaccharide + dTDP
Avermectin B1b monosaccharide + dTDP-L-oleandrose <=> Avermectin B1b + dTDP
Avermectin A1b aglycone + dTDP-L-oleandrose <=> Avermectin A1b monosaccharide + dTDP
Avermectin A1b monosaccharide + dTDP-L-oleandrose <=> Avermectin A1b + dTDP
beta-Amyrin + Oxygen <=> Soyasapogenol B
Erythromycin C + dTDP-L-megosamine <=> Megalomicin A + dTDP
Acetyl-CoA + 2 Malonyl-CoA <=> Triacetate lactone + 3 CoA + 2 CO2
apigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
kaempferol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Delphinidin 3-O-glucoside <=> Petunidin 3-O-glucoside
Delphinidin 3-O-glucoside <=> Malvidin 3-O-glucoside
Adenosyl cobinamide + GTP <=> Adenosyl cobinamide phosphate + GDP
formononetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)
biochanin A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)
Coniferyl aldehyde + NADPH + H+ + Oxygen <=> 5-Hydroxyconiferaldehyde + NADP+ + H2O
Coniferyl alcohol + NADPH + H+ + Oxygen <=> 5-Hydroxyconiferyl alcohol + NADP+ + H2O
4-Hydroxycinnamyl aldehyde <=> Caffeic aldehyde
trans-5-O-(4-coumaroyl)-D-shikimate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Kanosamine 6-phosphate <=> Aminofructose 6-phosphate
phosphoenolpyruvate:imino-D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate hydrolysing, 2-carboxy-2-oxoethyl-forming)
AminoDHQ <=> 5-Amino-5-deoxy-3-dehydroshikimate + H2O
Proansamycin X <=> 34a-Deoxy-rifamycin W
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+ <=> (R)(-)-Allantoin + CO2
daidzein,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)
genistein,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)
cis-1,2-Cyclohexanediol + NAD+ <=> 2-Hydroxycyclohexan-1-one + NADH
NADPH + 2-Hydroxycyclohexan-1-one + H+ + Oxygen <=> NADP+ + 1-Oxa-2-oxo-3-hydroxycycloheptane + H2O
4-Hydroxyphenylglyoxylate + L-Tyrosine <=> L-4-Hydroxyphenylglycine + 3-(4-Hydroxyphenyl)pyruvate
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + S-Adenosyl-L-methionine <=> dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose + S-Adenosyl-L-homocysteine
dTDP-L-4-oxovancosamine + NADPH + H+ <=> dTDP-L-epivancosamine + NADP+
Acetyl-CoA + 7 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 7 CO2 + 7 CoA
Butanoyl-CoA + 7 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-octadecanoyl-[acp] + 7 CO2 + 7 CoA
Malonamoyl-CoA + 8 Malonyl-CoA + Acyl-carrier protein <=> 18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + 8 CO2 + 9 CoA
18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + NADPH + H+ <=> C-9 Reduced nonaketamide + NADP+
10 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] + 10 CO2 + 10 CoA
Propanoyl-CoA + 9 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-henicosanoyl-[acp] + 9 CO2 + 9 CoA
Butanoyl-CoA + 9 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-docosanoyl-[acp] + 9 CO2 + 9 CoA
Urdamycinone B + dTDP-beta-L-rhodinose <=> 100-1 + dTDP
104-2 + dTDP-beta-L-rhodinose + dTDP-D-olivose <=> 124-1 + 2 dTDP
Urdamycinone F + 2 dTDP-beta-L-rhodinose + dTDP-D-olivose <=> Urdamycin F + 3 dTDP
Aquayamycin + dTDP-beta-L-rhodinose <=> 100-2 + dTDP
100-2 + dTDP-beta-L-rhodinose <=> Urdamycin G + dTDP
Rhodomycin D + H2O <=> 10-Carboxy-13-deoxycarminomycin + Methanol
10-Carboxy-13-deoxycarminomycin <=> 13-Deoxycarminomycin + CO2
6-Deoxydihydrokalafungin + Oxygen <=> Dihydrokalafungin + H2O
Tetracenomycin F1 <=> Tetracenomycin F1 methylester
Tetracenomycin F1 <=> Decarboxytetracenomycin F1
Tetracenomycin D3 <=> Tetracenomycin D3 methylester
Premithramycin A2' + dTDP-D-mycarose <=> Premithramycin A3' + dTDP
Retronecine + 2 L-Isoleucine <=> Senecionine
1-Methylpyrrolinium + Benzoate <=> Cocaine
Ecgonine methyl ester + H2O <=> Ecgonine + Methanol
Pseudoecgonine + ATP + CoA <=> Pseudoecgonyl-CoA + AMP
L-Tyrosine + Peptidyl-carrier protein + ATP <=> L-Tyrosyl-[pcp] + AMP + Diphosphate
L-Tyrosyl-[pcp] + Oxygen <=> beta-Hydroxy-L-tyrosyl-[pcp] + H2O
Coumermic acid + 2 dTDP-5-dimethyl-L-lyxose + 2 S-Adenosyl-L-methionine <=> Coumermycin D + 2 dTDP + 2 S-Adenosyl-L-homocysteine
Coumermycin D + 2 Pyrrole-2-carbonyl-[pcp] <=> Coumermycin A1
Chlorobiocic acid + dTDP-5-dimethyl-L-lyxose <=> Novclobiocin 105 + dTDP
Novclobiocin 105 + S-Adenosyl-L-methionine <=> Novclobiocin 104 + S-Adenosyl-L-homocysteine
Novclobiocin 104 + Pyrrole-2-carbonyl-[pcp] <=> Clorobiocin
3-Amino-4,7-dihydroxy-8-chlorocoumarin + 3-Dimethylallyl-4-hydroxybenzoate <=> Chlorobiocic acid
3-Methylpyrrole-2,4-dicarboxylic acid + 3-Amino-4,7-dihydroxycoumarin + ATP <=> 5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + AMP + Diphosphate
5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + 3-Amino-4,7-dihydroxycoumarin + ATP + 2 S-Adenosyl-L-methionine <=> Coumermic acid + AMP + Diphosphate + 2 S-Adenosyl-L-homocysteine
Nicotinate + 3,6-Dihydropyridine <=> Anatabine + CO2
Apigenin + 2 NADPH + 2 H+ + Oxygen <=> 2-Hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O
Pelargonidin 3-O-glucoside <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside
Pelargonidin 3-O-glucoside + UDP-L-rhamnose <=> Pelargonidin 3-O-rutinoside + UDP
Chrysanthemin + UDP-L-rhamnose <=> Cyanidin 3-O-rutinoside + UDP
2-Aminomalonate semialdehyde <=> Aminoacetaldehyde + CO2
Hydroquinone + NADPH + H+ + Oxygen <=> Benzene-1,2,4-triol + NADP+ + H2O
4-Hydroxyaniline + H2O <=> p-Benzoquinone + Ammonia
2-Hydroxy-1,4-benzoquinone <=> p-Benzoquinone + H2O
2-Chloro-3-oxoadipate <=> Chloroacetic acid + Succinate
3-Hexaprenyl-4-hydroxybenzoate + Oxygen <=> 3-Hexaprenyl-4,5-dihydroxybenzoate + H2O
3-Hexaprenyl-4-hydroxy-5-methoxybenzoate <=> 2-Hexaprenyl-6-methoxyphenol + CO2
Tetrabromobisphenol A <=> Tribromobisphenol A + Hydrobromic acid
Tribromobisphenol A <=> Dibromobisphenol A + Hydrobromic acid
Dibromobisphenol A <=> Monobromobisphenol A + Hydrobromic acid
Monobromobisphenol A <=> Bisphenol A + Hydrobromic acid
2 Bisphenol A <=> 4-Methyl-2,4-bis-(p-hydroxyphenyl)pent-1-ene
Bisphenol A + NADH + H+ + Oxygen <=> 1,2-Bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O
Bisphenol A + NADH + H+ + Oxygen <=> 2,2-Bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O
1,2-Bis(4-hydroxyphenyl)-2-propanol <=> 4,4'-Dihydroxy-alpha-methylstilbene + H2O
4,4'-Dihydroxy-alpha-methylstilbene + Oxygen <=> 4-Hydroxybenzaldehyde + 4'-Hydroxyacetophenone
2,2-Bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + Oxygen <=> 2,3-Bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O
2,3-Bis(4-hydroxyphenyl)-1,2-propanediol <=> 4-Hydroxyphenacyl alcohol + 4-Hydroxybenzoate
4-Ethylphenol + NADPH + H+ + Oxygen <=> 1-(4'-Hydroxyphenyl)ethanol + NADP+ + H2O
1-(4'-Hydroxyphenyl)ethanol + NAD+ <=> 4'-Hydroxyacetophenone + NADH + H+
UDP-N-acetyl-D-galactosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-D-galactosaminuronic acid + 2 NADH + 2 H+
2-Naphthoic acid <=> 5,6,7,8-Tetrahydro-2-naphthoic acid
5,6,7,8-Tetrahydro-2-naphthoic acid <=> Decahydro-2-naphthoic acid
5,6,7,8-Tetrahydro-2-naphthoic acid <=> cis-2-Carboxycyclohexyl-acetic acid
2-Naphthoic acid + FADH2 + Oxygen <=> 1-Hydroxy-2-naphthoate + FAD + H2O
2-Methylnaphthalene + Fumarate <=> 2-Naphtylmethylsuccinic acid
2-Naphtylmethylsuccinic acid + Succinyl-CoA <=> Naphthyl-2-methyl-succinyl-CoA + Succinate
Naphthyl-2-methyl-succinyl-CoA <=> Naphthyl-2-methylene-succinyl-CoA + 2 H+
Naphthyl-2-methylene-succinyl-CoA + H2O <=> Naphthyl-2-hydroxymethyl-succinyl CoA
Naphthyl-2-hydroxymethyl-succinyl CoA <=> Naphthyl-2-oxomethyl-succinyl-CoA + 2 H+
Naphthyl-2-oxomethyl-succinyl-CoA + CoA <=> 2-Naphthoyl-CoA + Succinyl-CoA
1,2-Dihydroxy-8-methylnaphthalene + Oxygen <=> 2-Hydroxy-8-methylchromene-2-carboxylate
2-Hydroxy-3-methylbenzalpyruvate + H2O <=> 3-Methylsalicylaldehyde + Pyruvate
3-Methylsalicylaldehyde + NAD+ + H2O <=> 3-Methylsalicylate + NADH + H+
1-Methylnaphthalene + Oxygen + NADH + H+ <=> 1-Hydroxymethylnaphthalene + NAD+ + H2O
1-Naphthaldehyde + NAD+ + H2O <=> 1-Naphthoic acid + NADH + H+
1-Naphthoic acid + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+
1,2-Dihydroxy-8-carboxynaphthalene + Oxygen <=> 2-Carboxy-2-hydroxy-8-carboxychromene
2-Hydroxy-3-carboxybenzalpyruvate + H2O <=> 3-Formylsalicylic acid + Pyruvate
3-Formylsalicylic acid + Oxygen + H2O <=> 2-Hydroxyisophthalic acid + Hydrogen peroxide
2-Hydroxyisophthalic acid <=> Salicylate + CO2
2-Methylnaphthalene + Oxygen + NADH + H+ <=> (2-Naphthyl)methanol + NAD+ + H2O
2-Naphthaldehyde + NAD+ + H2O <=> 2-Naphthoic acid + NADH + H+
1,2-Dihydroxy-7-hydroxymethylnaphthalene + Oxygen <=> 2-Hydroxy-7-hydroxymethylchromene-2-carboxylate
2-Hydroxy-4-hydroxymethylbenzalpyruvate + H2O <=> 4-Hydroxymethylsalicylaldehyde + Pyruvate
4-Hydroxymethylsalicylaldehyde + NAD+ + H2O <=> 4-Hydroxymethylsalicylate + NADH + H+
N-Cyclohexylformamide + H2O <=> Cyclohexylamine + Formate
Adipyl-CoA + FAD <=> 5-Carboxy-2-pentenoyl-CoA + FADH2
Adipate + CoA + ATP <=> Adipyl-CoA + AMP + Diphosphate
Cyclohexane + Oxygen + NADH + H+ <=> Cyclohexanol + NAD+ + H2O
carotenoid psi-end group lyase (decyclizing)
Cyromazine + H2O <=> N-Cyclopropylammeline + Ammonia
N-Cyclopropylammeline + H2O <=> N-Cyclopropylammelide + Ammonia
N-Cyclopropylammelide + H2O <=> Cyanuric acid + Cyclopropylamine
ATP + Lombricine <=> ADP + N-Phospholombricine
Rifamycin W-hemiacetal <=> Demethyl-desacetyl-rifamycin S
Rifamycin Z <=> Demethyl-desacetyl-rifamycin S
Demethyl-desacetyl-rifamycin S <=> 27-O-Demethyl-25-O-desacetylrifamycin SV
Acetyl-CoA + 27-O-Demethyl-25-O-desacetylrifamycin SV <=> CoA + 27-O-Demethylrifamycin SV
naphthalene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Naphthalene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
1,2-Dihydronaphthalene-1,2-diol, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
beta-Naphthol, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
1-nitronaphthalene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19(S)-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 14,15-EET + NADP+ + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 11,12-EET + NADP+ + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 8,9-EET + NADP+ + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 5,6-EET + NADP+ + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 16(R)-HETE + NADP+ + H2O
Linoleate + Oxygen + NADPH + H+ <=> 9(10)-EpOME + NADP+ + H2O
Linoleate + Oxygen + NADPH + H+ <=> 12(13)-EpOME + NADP+ + H2O
GDP-4-keto-6-L-deoxygalactose + NADPH + H+ <=> GDP-L-fucose + NADP+
bromobenzene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Delta-12-Prostaglandin J2 <=> 15-Deoxy-Delta12,14-PGJ2 + H2O
4-bromophenol, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Benzpyrene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
benzo[a]pyrene-7,8-diol, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
9-hydroxybenzo[a]pyrene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
1,1-dichloroethylene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
2,2-Dichloroacetaldehyde + H2O <=> 2,2-Dichloro-1,1-ethanediol
Chloroacetyl chloride + H2O <=> Chloroacetic acid
2-(S-Glutathionyl)acetyl chloride + H2O <=> 2-S-Glutathionyl acetate
trichloroethene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
trichloroethanol, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
1,2-dibromoethane,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
S-(Formylmethyl)glutathione <=> Thiodiacetic acid sulfoxide
Glutathione episulfonium ion + H2O <=> S-(2-Hydroxyethyl)glutathione
Glutathione episulfonium ion <=> S-[2-(N7-Guanyl)ethyl]-N-acetyl-L-cysteine
2-(S-Glutathionyl)acetyl glutathione + H2O <=> 2-S-Glutathionyl acetate + Glutathione
Dolichyl phosphate D-mannose + G00149 <=> Dolichyl phosphate + G00140
G02047 + 2 UDP-N-acetyl-D-glucosamine <=> G06302 + 2 UDP
N,N-Dihydroxy-L-tyrosine <=> (E)-4-Hydroxyphenylacetaldehyde oxime + CO2 + H2O
ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)
2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (cyclizing)
4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (cyclizing)
liquiritigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (licodione-forming)
abscisate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8'-hydroxylating)
lithocholate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6beta-hydroxylating)
5beta-cholestane-3alpha,7alpha-diol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating)
taurochenodeoxycholate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
lithocholate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
S-Adenosyl-L-methionine + [Cytochrome c]-arginine <=> S-Adenosyl-L-homocysteine + [Cytochrome c]-N(omega)-methylarginine
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)
D-ribulose 5-phosphate formate-lyase (L-3,4-dihydroxybutan-2-one 4-phosphate-forming)
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)
sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming)
flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
3'-hydroxyflavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5'-hydroxylating)
isoflavone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)
Phosphatidylcholine + L-Serine <=> Phosphatidylserine + Choline
1-(1-Alkenyl)-sn-glycero-3-phosphate + Acyl-CoA <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + CoA
2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + H2O <=> 1-Alkenyl-2-acylglycerol + Orthophosphate
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + Ethanolamine
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + Choline <=> Plasmenylcholine + Ethanolamine
1-Alkyl-2-acylglycerol + CDP-choline <=> 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + CMP
2 Phosphatidylglycerol <=> Cardiolipin + Glycerol
4-Methylthio-2-oxobutanoic acid + L-Glutamate <=> L-Methionine + 2-Oxoglutarate
Acetyl-CoA + Pyruvate + H2O <=> (R)-2-Methylmalate + CoA
(7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + Hydrogen peroxide <=> (7R)-7-(4-Carboxybutanamido)cephalosporanate + CO2 + H2O
indole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating)
2-Amino-3-oxo-4-phosphonooxybutyrate <=> 3-Amino-2-oxopropyl phosphate + CO2
ferroheme o:acceptor C-81-oxidoreductase (heme a-forming)
Digalacturonate + H2O <=> 2 D-Galacturonate
gamma-L-Glutamylputrescine + H2O + Oxygen <=> gamma-Glutamyl-gamma-aminobutyraldehyde + Ammonia + Hydrogen peroxide
Phosphocreatine <=> Creatinine + Orthophosphate
indolin-2-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating)
3-hydroxyindolin-2-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming)
2-hydroxy-2H-1,4-benzoxazin-3(4H)-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Ferulate + NADPH + H+ + Oxygen <=> 5-Hydroxyferulic acid methyl ester + NADP+ + H2O
D-ribulose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase
Campestanol + Oxygen + Reduced acceptor <=> 6alpha-Hydroxycampestanol + H2O + Acceptor
Cycloartenol + S-Adenosyl-L-methionine <=> 24-Methylidenecycloartanol + S-Adenosyl-L-homocysteine
4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+ <=> 4alpha-Methylfecosterol + NADP+
Isofucosterol + NADPH + H+ <=> beta-Sitosterol + NADP+
24-Methylenecholesterol + NADPH + H+ <=> Campesterol + NADP+
4alpha-Methylzymosterol-4-carboxylate + NADP+ <=> 3-Keto-4-methylzymosterol + NADPH + H+ + CO2
Zymosterol + NADPH + H+ <=> 5alpha-Cholest-8-en-3beta-ol + NADP+
14-Demethyllanosterol + NADPH + H+ <=> 4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+
7-Dehydrodesmosterol + NADPH + H+ <=> 7-Dehydrocholesterol + NADP+
alpha-carotene,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
zeinoxanthin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating)
Hydroxyspheroidene + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> Hydroxyspheroidenone + 3 H2O + 4 Oxidized ferredoxin
Hydroxychlorobactene glucoside <=> Hydroxychlorobactene glucoside ester
1'-Hydroxy-gamma-carotene glucoside <=> 1'-Hydroxy-gamma-carotene glucoside ester
(2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside) <=> (3R,2'S)-Myxol 2'-(2,4-di-O-methyl-alpha-L-fucoside)
(2'S)-Deoxymyxol 2'-alpha-L-fucoside <=> (3R,2'S)-Myxol 2'-alpha-L-fucoside
beta-carotene,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
beta-cryptoxanthin,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
echinenone,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
canthaxanthin,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
3'-hydroxyechinenone,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
3-hydroxyechinenone,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
phoenicoxanthin,reduced ferredoxin [iron-sulfur] cluster:oxygen 3'-oxidoreductase
3-Methyl-2-oxobutanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxypropyl-ThPP + CO2
2-Methyl-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + Thiamin diphosphate
4-Methyl-2-oxopentanoate + Thiamin diphosphate <=> 3-Methyl-1-hydroxybutyl-ThPP + CO2
3-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
(S)-3-Methyl-2-oxopentanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxybutyl-ThPP + CO2
2-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
UDP-N-acetyl-D-galactosamine + Sda antigen - related compound <=> UDP + Sda antigen
UDP-N-acetyl-D-galactosamine + G00388 <=> UDP + G05309
UDP-N-acetyl-D-galactosamine + G05309 <=> UDP + G00704
UDP-N-acetyl-D-galactosamine + G00025 <=> UDP + G13023
UDP-N-acetyl-D-galactosamine + G01977 <=> UDP + G13024
UDP-N-acetyl-D-galactosamine + G01941 <=> UDP + G13025
UDP-D-galactose + G00025 <=> UDP + G11136
UDP-N-acetyl-D-glucosamine + G13027 <=> UDP + G13026
Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + G13027
UDP-N-acetyl-D-glucosamine + G13026 <=> UDP + G13028
UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G10818
UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G13030
UDP-N-acetyl-D-glucosamine + G10818 <=> UDP + G13029
UDP-N-acetyl-D-glucosamine + G13030 <=> UDP + G13029
UDP-D-galactose + G00031 <=> UDP + G00032
3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming)
2 ATP + HCO3- + Ammonia <=> 2 ADP + Orthophosphate + Carbamoyl phosphate
L-amino acid:L-amino acid ligase (ADP-forming)
UDP-glucuronate + NAD+ <=> UDP-L-Ara4O + CO2 + NADH + H+
UDP-L-Ara4O + L-Glutamate <=> UDP-L-Ara4N + 2-Oxoglutarate
10-Formyltetrahydrofolate + UDP-L-Ara4N <=> Tetrahydrofolate + UDP-L-Ara4FN
Toluene-4-sulfonate + Oxygen <=> 4-Cresol + Sulfate
3-Cresol + Oxygen + NADH + H+ <=> 3-Hydroxybenzyl alcohol + NAD+ + H2O
Vanillate + Cob(I)alamin <=> 3,4-Dihydroxybenzoate + Methylcobalamin
Protein N(pi)-phospho-L-histidine + Ascorbate <=> Protein histidine + L-Ascorbate 6-phosphate
L-Ascorbate 6-phosphate + H2O <=> 3-Dehydro-L-gulonate 6-phosphate
Ascorbate + 2 Ferricytochrome c <=> Dehydroascorbate + 2 Ferrocytochrome c + 2 H+
L-Galactono-1,4-lactone + H2O <=> L-Galactonate
1,2-Dihydroxynaphthalene-6-sulfonate + Oxygen <=> (Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate
(Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate + 2 H2O <=> 5-Sulfosalicylate + Pyruvate
5-Sulfosalicylate + Oxygen <=> 2,5-Dihydroxybenzoate + Sulfate
Anthracene + Oxygen + 2 H+ + 2 e- <=> Anthracene-9,10-dihydrodiol
Anthracene-9,10-dihydrodiol <=> 9,10-Dihydroxyanthracene + 2 H+
9,10-Dihydroxyanthracene <=> Anthraquinone + 2 H+
3-Hydroxy-2-naphthoate + Oxygen <=> 3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate
4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid + 2 H2O <=> 3-Hydroxy-2-naphthoate + Pyruvate
Phenylboronic acid + Oxygen <=> Phenol + Boric acid
1,2-Anthracenediol + Oxygen <=> 4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid
1,2-Anthracenediol + Oxygen <=> 3-(2-Carboxyvinyl)naphthalene-2-carboxylic acid
trans-9(S),10(S)-Dihydrodiolphenanthrene <=> 9-Hydroxyphenanthrene + H2O
Liquiritigenin + NADPH + H+ + Oxygen <=> 6,7,4'-Trihydroxyflavanone + NADP+ + H2O
7,4'-Dihydroxyflavone + 2 NADPH + 2 H+ + Oxygen <=> 2,7,4'-Trihydroxyisoflavanone + 2 NADP+ + H2O
6,7,4'-trihydroxyflavanone, [reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration)
o-Nitrobenzoate + 2 NADPH + 2 H+ <=> o-Hydroxylaminobenzoate + 2 NADP+ + H2O
o-Hydroxylaminobenzoate + 2 H+ <=> Anthranilate + H2O
Medicarpin + NADPH + H+ <=> (-)-Vestitol + NADP+
calycosin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming)
pseudobaptigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)
Malonyl-CoA + Palmitoyl-CoA <=> 3-Oxostearoyl-CoA + CoA + CO2
3-Hydroxyoctadecanoyl-CoA <=> (2E)-Octadecenoyl-CoA + H2O
Hexadecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxostearoyl-[acp] + Acyl-carrier protein + CO2
3-Oxostearoyl-[acp] + NADPH + H+ <=> (R)-3-Hydroxyoctadecanoyl-[acp] + NADP+
(R)-3-Hydroxyoctadecanoyl-[acp] <=> (2E)-Octadecenoyl-[acp] + H2O
[protein]-N6-(octanoyl)-L-lysine:an [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster sulfurtransferase
ATP + (R)-Lipoate <=> Diphosphate + Lipoyl-AMP
Lipoyl-AMP + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + AMP
biochanin A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
liquiritigenin, [reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration)
naringenin, [reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration)
3,5-Dibromo-4-hydroxybenzamide + H2O <=> 3,5-Dibromo-4-hydroxybenzoate + Ammonia
22alpha-hydroxy-campesterol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating)
22alpha-hydroxy-campest-4-en-3-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating)
22alpha-hydroxy-5alpha-campestan-3-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating)
3-epi-6-deoxocathasterone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating)
4-Chloroaniline + Oxygen + 2 H+ <=> 4-Chlorocatechol + Ammonia
2,4-Dichloroaniline + 2 H+ <=> 4-Chloroaniline + Hydrochloric acid
Fluoren-9-one + Oxygen + H+ + NADH <=> 1-Hydro-1,1a-dihydroxy-9-fluorenone + NAD+
1-Hydro-1,1a-dihydroxy-9-fluorenone + H2O <=> 2,3-Dihydroxy-2'-carboxybiphenyl + 2 H+
2,3-Dihydroxy-2'-carboxybiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate
2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O <=> Phthalate + 2-Hydroxy-2,4-pentadienoate
(+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene <=> 3,4-Dihydroxyfluorene + 2 H+
G13074 + H2O <=> G01391 + N-Acetyl-D-glucosamine
G13073 + H2O <=> G01391 + N-Acetyl-D-glucosamine 6-sulfate
Heparan sulfate + H2O <=> Heparan sulfate + G13034
G13035 + H2O <=> G13036 + L-Iduronic acid
G13038 + H2O <=> G13039 + N-Acetyl-D-glucosamine
Dermatan sulfate + H2O <=> Dermatan sulfate + G13041
G13042 + H2O <=> G12336 + L-Iduronic acid
G13043 + H2O <=> DWA-2 + N-Acetylgalactosamine
G12336 + H2O <=> DWA-2 + N-Acetylgalactosamine 4-sulfate
Cyclopropanecarboxylate + CoA + ATP <=> Cyclopropanecarboxyl-CoA + ADP + Orthophosphate
Dihydrophloroglucinol + H2O <=> 3-Hydroxy-5-oxohexanoate
3-Hydroxy-5-oxohexanoyl-CoA + CoA <=> (S)-3-Hydroxybutanoyl-CoA + Acetyl-CoA
Terephthalate + H2O <=> Benzoate + Carbonic acid
Thiobenzamide + Oxygen + NADPH + H+ <=> Thiobenzamide S-oxide + NADP+ + H2O
Thiobenzamide S-oxide + NADPH + H+ + Oxygen <=> Thiobenzamide S,S-dioxide + NADP+ + H2O
alpha-carotene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating)
alpha-cryptoxanthin,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid
Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid
(9Z,12Z,15Z)-Octadecatrienoic acid + Reduced acceptor + Oxygen <=> Stearidonic acid + Acceptor + 2 H2O
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 9(S)-HPOT
9(S)-HPOT <=> 9-Oxononanoic acid + 3,6-Nonadienal
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 13(S)-HPOT
13(S)-HPOT <=> 12-Oxo-9(Z)-dodecenoic acid + 3-Hexenal
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) + UDP-glucose <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + UDP
2-Naphthoyl-CoA + H2O <=> 2-Naphthoic acid + CoA
Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=> Pelargonidin 3-O-3'',6''-O-dimalonylglucoside + CoA
Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=> Cyanidin 3-O-3'',6''-O-dimalonylglucoside + CoA
Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + Malonyl-CoA <=> Delphinidin 3-O-3'',6''-O-dimalonylglucoside + CoA
ATP + 8-[(1R,2R)-3-Oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate + CoA <=> AMP + Diphosphate + OPC8-CoA
OPC8-CoA + FAD <=> trans-2-Enoyl-OPC8-CoA + FADH2
3-Hydroxy-OPC8-CoA <=> trans-2-Enoyl-OPC8-CoA + H2O
3-Hydroxy-OPC8-CoA + NAD+ <=> 3-Oxo-OPC8-CoA + NADH + H+
OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA
OPC6-CoA + FAD <=> trans-2-Enoyl-OPC6-CoA + FADH2
3-Hydroxy-OPC6-CoA <=> trans-2-Enoyl-OPC6-CoA + H2O
3-Hydroxy-OPC6-CoA + NAD+ <=> 3-Oxo-OPC6-CoA + NADH + H+
OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA
OPC4-CoA + FAD <=> trans-2-Enoyl-OPC4-CoA + FADH2
3-Hydroxy-OPC4-CoA <=> trans-2-Enoyl-OPC4-CoA + H2O
3-Hydroxy-OPC4-CoA + NAD+ <=> 3-Oxo-OPC4-CoA + NADH + H+
(+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA
(+)-7-Isojasmonic acid CoA + H2O <=> CoA + (+)-7-Isojasmonic acid
Delphinidin 3-O-glucoside + UDP-L-rhamnose <=> Tulipanin + UDP
S-Adenosyl-L-methionine + 7-Methylxanthine <=> S-Adenosyl-L-homocysteine + 1,7-Dimethylxanthine
alpha-linolenoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (6,7 cis-dehydrogenating)
(R,S)-Nicotine + Acceptor + H2O <=> (R)-6-Hydroxynicotine + Reduced acceptor
2,6-Dihydroxypseudooxynicotine <=> 2,6-Dihydroxy-N-methylmyosmine + H2O
2 2,3,6-Trihydroxypyridine + 2 Oxygen <=> Blue pigment + 2 Hydrogen peroxide
2,3,6-Trihydroxypyridine + Oxygen + H+ <=> Maleamate + 2 H+ + CO2
1,7-Dimethylxanthine + NADH + H+ + Oxygen <=> 1-Methylxanthine + NAD+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADPH + H+ + Oxygen <=> 1-Methylxanthine + NADP+ + Formaldehyde + H2O
Theobromine + NADH + H+ + Oxygen <=> 3-Methylxanthine + NAD+ + Formaldehyde + H2O
Theobromine + NADPH + H+ + Oxygen <=> 3-Methylxanthine + NADP+ + Formaldehyde + H2O
Caffeine + NADH + H+ + Oxygen <=> Theophylline + NAD+ + Formaldehyde + H2O
Caffeine + NADPH + H+ + Oxygen <=> Theophylline + NADP+ + Formaldehyde + H2O
1,3,7-Trimethyluric acid + Oxygen + 2 H2O <=> 3,6,8-Trimethylallantoin + CO2 + Hydrogen peroxide
3,6,8-Trimethylallantoin + 2 H2O <=> N,N'-Dimethylurea + N-Methylurea + Glyoxylate
2,6-Dihydroxynicotinate + H2O + Oxygen <=> Maleamate + CO2 + Formate
(S)-2-(Hydroxymethyl)glutarate <=> 2-Methyleneglutarate + H2O
liquiritigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Naringenin chalcone + Dimethylallyl diphosphate <=> Desmethylxanthohumol + Diphosphate
Naringenin chalcone + UDP-glucose <=> Phlorizin chalcone + UDP
Trinitrotoluene + 2 NADPH + 2 H+ <=> 4-Hydroxylamino-2,6-dinitrotoluene + 2 NADP+ + H2O
4-Hydroxylamino-2,6-dinitrotoluene + 2 NADPH + 2 H+ <=> 2,4-Dihydroxylamino-6-nitrotoluene + 2 NADP+ + H2O
2,4-Dihydroxylamino-6-nitrotoluene + NADPH + H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + NADP+ + H2O
Trinitrotoluene + 2 NADH + 2 H+ <=> 4-Hydroxylamino-2,6-dinitrotoluene + 2 NAD+ + H2O
4-Hydroxylamino-2,6-dinitrotoluene + NADH + H+ <=> 4-Amino-2,6-dinitrotoluene + NAD+ + H2O
4-Hydroxylamino-2,6-dinitrotoluene + NADPH + H+ <=> 4-Amino-2,6-dinitrotoluene + NADP+ + H2O
4 4-Hydroxylamino-2,6-dinitrotoluene + Oxygen <=> 2 2,2',6,6'-Tetranitro-4,4'-azoxytoluene + 4 H2O
Eriodictyol chalcone <=> Homoeriodictyol chalcone
garbanzol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
2 4-Hydroxylamino-2,6-dinitrotoluene + 2 2-Hydroxylamino-4,6-dinitrotoluene + Oxygen <=> 2 2,4',6,6'-Tetranitro-2',4-azoxytoluene + 4 H2O
4 2-Hydroxylamino-4,6-dinitrotoluene + Oxygen <=> 2 4,4',6,6'-Tetranitro-2,2'-azoxytoluene + 4 H2O
Trinitrotoluene + 2 NADH + 2 H+ <=> 2-Hydroxylamino-4,6-dinitrotoluene + 2 NAD+ + H2O
2-Hydroxylamino-4,6-dinitrotoluene + NADH + H+ <=> 2-Amino-4,6-dinitrotoluene + NAD+ + H2O
2-Amino-4,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,6-Diamino-4-nitrotoluene + 3 NAD+ + 2 H2O
2-Amino-4,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diamino-6-nitrotoluene + 3 NAD+ + 2 H2O
4-Amino-2,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diamino-6-nitrotoluene + 3 NAD+ + 2 H2O
4-Amino-2,6-dinitrotoluene + 2 NADH + 2 H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + 2 NAD+ + H2O
Ectoine + 2-Oxoglutarate + Oxygen <=> 5-Hydroxyectoine + Succinate + CO2
5,10-Methylenetetrahydromethanopterin + NADP+ <=> 5,10-Methenyltetrahydromethanopterin + NADPH
Formylmethanofuran + H2O <=> Formate + Methanofuran
Isopentenyladenosine-5'-triphosphate + H2O <=> Isopentenyladenosine-5'-diphosphate + Orthophosphate
Isopentenyladenosine-5'-diphosphate + H2O <=> N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + Orthophosphate
trans-Zeatin riboside triphosphate + H2O <=> trans-Zeatin riboside diphosphate + Orthophosphate
trans-Zeatin riboside diphosphate + H2O <=> trans-Zeatin riboside monophosphate + Orthophosphate
trans-Zeatin riboside monophosphate <=> Dihydrozeatin riboside monophosphate
trans-Zeatin riboside <=> Dihydrozeatin riboside
N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + H2O <=> Isopentenyl adenosine + Orthophosphate
trans-Zeatin riboside monophosphate + H2O <=> trans-Zeatin riboside + Orthophosphate
Dihydrozeatin riboside monophosphate + H2O <=> Dihydrozeatin riboside + Orthophosphate
Isopentenyl adenosine + H2O <=> N6-(Delta2-Isopentenyl)-adenine + D-Ribose
trans-Zeatin riboside + H2O <=> Zeatin + D-Ribose
Dihydrozeatin riboside + H2O <=> Dihydrozeatin + D-Ribose
Zeatin + UDP-glucose <=> trans-Zeatin-7-beta-D-glucoside + UDP
Dihydrozeatin + UDP-glucose <=> Dihydrozeatin-O-glucoside + UDP
tRNA containing 6-isopentenyladenosine <=> cis-Prenyl-tRNA
cis-Prenyl-tRNA <=> cis-Zeatin riboside monophosphate
cis-Zeatin riboside monophosphate + H2O <=> cis-Zeatin riboside + Orthophosphate
cis-Zeatin riboside + H2O <=> cis-Zeatin + D-Ribose
Nerol + NADP+ <=> cis-Citral + NADPH + H+
beta-Citronellol + NADP+ <=> (R)-(+)-Citronellal + NADPH + H+
(-)-Citronellol + NADP+ <=> (S)-(-)-Citronellal + NADPH + H+
(R)-(+)-Citronellal + NAD+ + H2O <=> Citronellate + NADH + H+
Citronellyl-CoA + Acceptor <=> Geranoyl-CoA + Reduced acceptor
5-Methylhex-4-enoyl-CoA + FAD <=> (2E)-5-Methylhexa-2,4-dienoyl-CoA + FADH2
(S)-(-)-Citronellal + NAD+ + H2O <=> Citronellate + NADH + H+
Geranic acid + CoA <=> trans-Geranyl-CoA + H2O
Fluorobenzene + NADH + Oxygen + H+ <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+
Fluorobenzene + NADH + H+ + Oxygen <=> 1-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+
4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+ <=> 4-Fluorocatechol + NADH + H+
1-Fluorocyclohexadiene-cis,cis-1,2-diol <=> Catechol + Hydrofluoric acid
Phosphatidylethanolamine + G00149 <=> 1,2-Diacyl-sn-glycerol + G13044
Fructoselysine 6-phosphate + H2O <=> L-Lysine + D-Glucose 6-phosphate
Kaempferol-3-O-galactoside + UDP-glucose <=> Kaempferol 3-O-beta-D-glucosylgalactoside + UDP
3-Dehydroecdysone + NADH + H+ <=> 3-Epiecdysone + NAD+
3-Dehydroecdysone + NADH + H+ <=> Ecdysone + NAD+
methyl (2E,6E)-farnesoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
(10S)-Juvenile hormone III diol + H2O <=> (10S)-Juvenile hormone III acid diol + Methanol
S-adenosyl-L-methionine:juvenile hormone III acid O-methyltransferase
Juvenile hormone III acid + H2O <=> (10S)-Juvenile hormone III acid diol
Juvenile hormone III + H2O <=> (10S)-Juvenile hormone III diol
(10S)-Juvenile hormone III diol + ATP <=> (10S)-Juvenile hormone III diol phosphate + ADP
Juvenile hormone III <=> 12-trans-Hydroxy juvenile hormone III
L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
hexadecanoyl-[acyl-carrier protein],reduced-ferredoxin:oxygen oxidoreductase (9,10 cis-dehydrogenating)
S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O <=> Indolylmethylthiohydroximate + Pyruvate + Ammonia
amino phenylpropanoyl-CoA:Baccatin III amino phenylpropanoyl-13-O-transferase
(9Z,12Z,15Z)-Octadecatrienoyl-CoA + H2O <=> CoA + (9Z,12Z,15Z)-Octadecatrienoic acid
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + H2O <=> CoA + (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid
gamma-Linolenoyl-CoA + H2O <=> CoA + (6Z,9Z,12Z)-Octadecatrienoic acid
8,11,14-Eicosatrienoyl-CoA + H2O <=> CoA + Dihomo-gamma-linolenate
Arachidonyl-CoA + H2O <=> CoA + Arachidonate
Docosanoyl-CoA + H2O <=> CoA + Docosanoic acid
Tetracosanoyl-CoA + H2O <=> CoA + Tetracosanoic acid
Icosenoyl-CoA + H2O <=> CoA + Icosenoic acid
Docosenoyl-CoA + H2O <=> CoA + Erucic acid
Tetracosenoyl-CoA + H2O <=> CoA + (15Z)-Tetracosenoic acid
(7Z,10Z,13Z,16Z,19Z)-Docosapentaenoyl-CoA + H2O <=> CoA + (7Z,10Z,13Z,16Z,19Z)-Docosapentaenoic acid
(11Z,14Z)-Icosadienoyl-CoA + H2O <=> CoA + Icosadienoic acid
(7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + H2O <=> CoA + Adrenic acid
(11Z,14Z,17Z)-Icosatrienoyl-CoA + H2O <=> CoA + Icosatrienoic acid
D-Allothreonine <=> Glycine + Acetaldehyde
2-Hydroxyglutarate + NAD+ <=> 2-Oxoglutarate + NADH + H+
3-Phosphonopyruvate + H2O <=> Pyruvate + Orthophosphate
ATP + 2-Oxoglutarate + HCO3- <=> ADP + Orthophosphate + Oxalosuccinate
Androstenedione + NADPH + H+ + Oxygen <=> Testololactone + NADP+ + H2O
17alpha-Hydroxyprogesterone + NADPH + H+ + Oxygen <=> Androstenedione + Acetate + NADP+ + H2O
2-Oxoglutarate + Acetyl-CoA <=> trans-Homoaconitate + CoA
Tegafur + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-FU + Succinic aldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O
Azathioprine <=> 6-Mercaptopurine + 1-Methyl-4-nitroimidazole
6-Thioinosine-5'-monophosphate + ATP <=> 6-Mercaptopurine ribonucleoside 5'-diphosphate + ADP
6-Mercaptopurine ribonucleoside 5'-diphosphate + ATP <=> 6-Mercaptopurine ribonucleoside triphosphate + ADP
Isonicotinic acid + Glycine <=> Isonicotinylglycine
Isoniazid + Pyruvate <=> Isoniazid pyruvate + H2O
Isoniazid + 2-Oxoglutarate <=> Isoniazid alpha-ketoglutaric acid + H2O
Irinotecan + H2O <=> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid
Irinotecan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> NPC + Glutaral + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
NPC + H2O <=> SN-38 + 4-Amino-1-piperidinecarboxylic acid
SN-38 + UDP-glucuronate <=> SN38 glucuronide + UDP
UDP-glucuronate + Codeine <=> UDP + Codeine-6-glucuronide
Morphine + UDP-glucuronate <=> Morphine-3-glucuronide + UDP
Morphine + UDP-glucuronate <=> Morphine-6-glucuronide + UDP
Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Norcodeine + Formaldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O
Morphine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Normorphine + Formaldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O
Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O
N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O
Tamoxifen + NADPH + Oxygen + H+ <=> alpha-Hydroxytamoxifen + NADP+ + H2O
(13Z,16Z)-Docosadienoyl-CoA + H2O <=> CoA + (13Z,16Z)-Docosadienoic acid
N-Desmethyltamoxifen + NADPH + H+ + Oxygen <=> alpha-Hydroxy-N-desmethyltamoxifen + H2O + NADP+
Cyclophosphamide + NADPH + H+ + Oxygen <=> 4-Hydroxycyclophosphamide + NADP+ + H2O
Cyclophosphamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
Aldophosphamide <=> Phosphoramide mustard + Acrolein
Ifosfamide + NADPH + H+ + Oxygen <=> 4-Hydroxyifosfamide + NADP+ + H2O
Ifosfamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
Ifosfamide <=> 2-Dechloroethylifosfamide + Chloroacetaldehyde
Aldoifosfamide <=> Isophosphoramide mustard + Acrolein
Lidocaine + NADPH + Oxygen + H+ <=> 3-Hydroxylidocaine + NADP+ + H2O
Felbamate + NADPH + H+ + Oxygen <=> p-Hydroxyfelbamate + NADP+ + H2O
Felbamate + NADPH + H+ + Oxygen <=> 2-Hydroxyfelbamate + NADP+ + H2O
Felbamate + H2O <=> 2-Phenyl-1,3-propanediol monocarbamate + CO2 + Ammonia
3-Carbamoyl-2-phenylpropionaldehyde <=> Atropaldehyde + CO2 + Ammonia
5-Phenyl-1,3-oxazinane-2,4-dione + H2O <=> 3-Carbamoyl-2-phenylpropionic acid
Carbamazepine + NADPH + H+ + Oxygen <=> Carbamazepine-10,11-epoxide + NADP+ + H2O
Carbamazepine + NADPH + H+ + Oxygen <=> 3-Hydroxycarbamazepine + NADP+ + H2O
Carbamazepine-10,11-epoxide + H2O <=> Dihydroxycarbazepine
7-Mercaptoheptanoic acid + L-Threonine + ATP <=> 7-Mercaptoheptanoylthreonine + ADP + Orthophosphate
Valproic acid <=> 2-n-Propyl-4-pentenoic acid
Valproic acid + NADPH + H+ + Oxygen <=> 4-Hydroxyvalproic acid + NADP+ + H2O
Valproic acid + NADPH + H+ + Oxygen <=> 5-Hydroxyvalproic acid + NADP+ + H2O
Valproic acid + NADPH + H+ + Oxygen <=> 3-Hydroxyvalproic acid + NADP+ + H2O
2-Oxosuberate <=> 7-Oxoheptanoic acid + CO2
2-n-Propyl-4-pentenoic acid <=> 2-Propyl-2,4-pentadienoic acid
4-Hydroxyvalproic acid <=> 2-n-Propyl-4-oxopentanoic acid
acetyl-CoA:2-oxoadipate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
acetyl-CoA:2-oxopimelate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
2-n-Propyl-4-oxopentanoic acid <=> 2-Propylsuccinic acid
5-Hydroxyvalproic acid <=> 2-Propylglutaric acid
3-Hydroxyvalproic acid <=> 3-Oxovalproic acid
Valproic acid <=> 2-n-Propyl-2-pentenoic acid
Valproic acid <=> 2-n-Propyl-3-pentenoic acid
2-n-Propyl-2-pentenoic acid <=> 3-Hydroxyvalproic acid
Trypanothione + Dehydroascorbate <=> Trypanothione disulfide + Ascorbate
Trypanothione + Tryparedoxin disulfide <=> Trypanothione disulfide + Tryparedoxin
D-Galactosamine 6-phosphate + H2O <=> D-Tagatose 6-phosphate + Ammonia
1-Hydroxyalkyl-sn-glycerol <=> Aldehyde + Glycerol
9-cis-Retinol + NADP+ <=> 9-cis-Retinal + NADPH + H+
all-trans-retinyl ester acylhydrolase, 11-cis-retinol forming
Retinoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> all-trans-18-Hydroxyretinoic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Retinoate + NADPH + H+ + Oxygen <=> all-trans-5,6-Epoxyretinoic acid + NADP+ + H2O
Retinoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> all-trans-4-Hydroxyretinoic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Geranyl diphosphate <=> Car-3-ene + Diphosphate
DNA 2,6-diamino-5-formamido-3,4-dihydro-4-oxopyrimidine <=> DNA containing guanine + H2O
Xanthine + 2 S-Adenosyl-L-methionine <=> Theophylline + 2 S-Adenosyl-L-homocysteine
L-Histidine + 3-Methylbutanoic acid <=> Dolichotheline
Piperideine + trans-Cinnamate <=> (-)-Sedamine
Piperideine + trans-Cinnamate + Benzoyl-CoA <=> Lobelanine + CoA
1-Methylpyrrolinium <=> Ecgonine methyl ester
Ecgonine methyl ester + Benzoyl-CoA <=> Cocaine + CoA
Tyramine + 3,4-Dihydroxybenzaldehyde <=> Norcraugsodine + H2O
4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N-Demethylnarwedine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
N-Demethylnarwedine + NADPH <=> Norgalanthamine + NADP+
Dopamine + 4-Hydroxydihydrocinnamaldehyde <=> (S)-Autumnaline
(S)-Autumnaline + NADPH + Oxygen + H+ <=> Isoandrocymbine + NADP+ + 2 H2O
N-Formyldemecolcine + H2O <=> Demecolcine + Formate
Deacetylcolchicine + Acetyl-CoA <=> Colchicine + CoA
Floramultine + S-Adenosyl-L-methionine <=> Kreysigine + S-Adenosyl-L-homocysteine
(S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine <=> Tubocurarine
N-Acetylanthranilate + L-Aspartate <=> Peganine
gamma-Coniceine + NADPH + H+ <=> Coniine + NADP+
17alpha-Hydroxypregnenolone,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating, acetate-releasing)
17alpha-hydroxyprogesterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating, acetate-releasing)
[Thyroglobulin]-L-tyrosine + Iodine <=> [Thyroglobulin]-3-iodo-L-tyrosine + Hydroiodic acid
[Thyroglobulin]-3-iodo-L-tyrosine + Iodine <=> [Thyroglobulin]-3,5-diiodo-L-tyrosine + Hydroiodic acid
[Thyroglobulin]-3,5-diiodo-L-tyrosine + [Thyroglobulin]-3-iodo-L-tyrosine + Hydrogen peroxide <=> Thyroglobulin triiodothyronine + Thyroglobulin dehydroalanine + 2 H2O
2 [Thyroglobulin]-3,5-diiodo-L-tyrosine + Hydrogen peroxide <=> [Thyroglobulin]-L-thyroxine + Thyroglobulin dehydroalanine + 2 H2O
D-Fructose 1-phosphate + H2O <=> D-Fructose + Orthophosphate
(R)-lactate hydro-lyase (adding N-acetyl-D-glucosamine 6-phosphate
Choline + NAD+ <=> Betaine aldehyde + NADH + H+
Choline + NADP+ <=> Betaine aldehyde + NADPH + H+
Cyclic dehypoxanthine futalosine <=> 1,4-Dihydroxy-6-naphthoate
Indole-3-acetaldoxime N-oxide + L-Cysteine <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O
L-Aspartate 4-semialdehyde + Glycerone phosphate <=> 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O
L-valine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
4-methylthiobutanaldoxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (adding cysteine)
7alpha,26-Dihydroxy-4-cholesten-3-one + 2 Oxygen + 2 NADPH + 2 H+ <=> 7alpha-Hydroxy-3-oxo-4-cholestenoate + 2 NADP+ + 3 H2O
Cholest-5-ene-3beta,26-diol + 2 Oxygen + 2 NADPH + 2 H+ <=> 3beta-Hydroxy-5-cholestenoate + 2 NADP+ + 3 H2O
3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha-Dihydroxy-5beta-cholestanate + H2O + 2 Oxidized adrenal ferredoxin
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + H2O + 2 Oxidized adrenal ferredoxin
p-Coumaroyl-CoA + CoA + NAD+ + H2O <=> 4-Hydroxybenzoyl-CoA + Acetyl-CoA + NADH + H+
4-Hydroxy-3-polyprenylbenzoate + Oxygen <=> 3,4-Dihydroxy-5-polyprenylbenzoate + H2O
geraniol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + 3'-Hydroxy-N-methyl-(S)-coclaurine
p-Coumaroyl-CoA + Malonyl-CoA + Hexanoyl-CoA + H2O <=> 1-(4-Hydroxyphenyl)-1-decene-3,5-dione + 3 CoA + 2 CO2
Feruloyl-CoA + Malonyl-CoA + Hexanoyl-CoA + H2O <=> 1-Dehydro-[6]-gingerdione + 3 CoA + 2 CO2
p-coumaroyl-CoA:p-coumaroyl-diketide-CoA C-coumaroyltransferase (thioester-hydrolysing and decarboxylating)
feruloyl-CoA:p-Coumaroyl-diketide-CoA C-feruloyltransferase (thioester-hydrolysing and decarboxylating)
p-coumaroyl-CoA:feruloyl-diketide-CoA C-coumaroyltransferase (thioester-hydrolysing and decarboxylating)
cinnamoyl-CoA,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
cyclo-Dopa-glucuronylglucoside + Betalamic acid <=> Amaranthin + H2O
cyclo-Dopa 5-O-glucoside + Betalamic acid <=> Betanin + H2O
2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + Betalamic acid <=> Betanidin + H2O
L-Tyrosine + Betalamic acid <=> Portulacaxanthin II + H2O
3,4-Dihydroxy-L-phenylalanine + Betalamic acid <=> Dopaxanthin + H2O
3-Methoxytyramine + Betalamic acid <=> 3-Methoxytyramine-betaxanthin + H2O
2-Descarboxy-cyclo-dopa + Betalamic acid <=> 2-Descarboxy-betanidin + H2O
Dopamine + Betalamic acid <=> Miraxanthin-V + H2O
Dopaquinone + L-Cysteine <=> Cysteinyldopa
Phosphonoacetaldehyde + NADPH + H+ <=> 2-Hydroxyethylphosphonate + NADP+
acetyl-CoA:phosphinopyruvate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
Phosphonoformyl-CMP + 3-Phospho-D-glycerate <=> 1-Carboxyvinyl carboxyphosphonate + CMP + Orthophosphate
sophoraflavanone-B,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)
(+)-pulegone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (9-hydroxylating)
butyryl-[acyl-carrier protein]:S-adenosyl-L-methionine butyryltranserase (lactone-forming, methylthioadenosine-releasing)
acyl-[acyl-carrier protein]:S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing)
C-13(2)-Carboxypyropheophorbide a <=> Pyropheophorbide a + CO2
3 p-Coumaroyl-CoA + Spermidine <=> N1,N5,N10-Tricoumaroyl spermidine + 3 CoA
N1,N5,N10-Tricoumaroyl spermidine <=> N1,N5,N10-Tricaffeoyl spermidine
N1,N5,N10-Tricaffeoyl spermidine <=> N1,N5,N10-Triferuloyl spermidine
N1,N5,N10-Triferuloyl spermidine <=> N1,N5,N10-Tri(hydroxyferuloyl) spermidine
N1,N5,N10-Tri(hydroxyferuloyl) spermidine + S-Adenosyl-L-methionine <=> N1,N5-Di(hydroxyferuloyl)-N10-sinapoyl spermidine + S-Adenosyl-L-homocysteine
primary fluorescent chlorophyll catabolite:ferredoxin oxidoreductase
Acyl-CoA + Monolysocardiolipin <=> CoA + Cardiolipin
geranylhydroquinone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3''-hydroxylating)
3 Cadaverine + 4 Pyruvate <=> 17-Oxosparteine + 4 L-Alanine + 3 H2O
Bacteriochlorophyllide a <=> Bacteriochlorophyllide b
Reduced FMN + Oxygen <=> Dimethylbenzimidazole + D-Erythrose 4-phosphate + H2O
Benzoate + Pyruvate <=> Pyruvophenone + CO2
2-Methylpropanoyl-CoA + 3 Malonyl-CoA <=> 8-Methyl-6-nonenoic acid
Tetrahydrofolate + Formaldehyde <=> 5,10-Methylenetetrahydrofolate + H2O
Acetyl-CoA + 5,6,7,8-Tetrahydromethanopterin <=> CoA + 5-Methyl-5,6,7,8-tetrahydromethanopterin + CO
4-Hydroxyphenyl-4-hydroxybenzoate + H2O <=> 4-Hydroxybenzoate + Hydroquinone
geranylgeraniol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating)
1,2,3,4-Tetrachlorobenzene + Oxygen + NADH + H+ <=> cis-Chlorobenzene dihydrodiol + NAD+
1,2,3,4-Tetrachlorobenzene + Oxygen + NADPH + H+ <=> cis-Chlorobenzene dihydrodiol + NADP+
cis-Chlorobenzene dihydrodiol + NAD+ <=> Tetrachlorocatechol + NADH + H+
cis-Chlorobenzene dihydrodiol + NADP+ <=> Tetrachlorocatechol + NADPH + H+
Trichloroethene + NADH + H+ + Oxygen <=> TCE epoxide + NAD+ + H2O
1,1,1-Trichloroethane + NADH + H+ + Oxygen <=> Trichloroethanol + NAD+ + H2O
1,1,1-Trichloroethane <=> 1,1-Dichloroethane + Hydrochloric acid
1,1-Dichloroethane <=> Chloroethane + Hydrochloric acid
Trichloroacetate + 2 H2O <=> Oxalate + 3 Hydrochloric acid
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-9,10-dihydrodiol + NAD+
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-7,8-dihydrodiol + NAD+
Pyrene + Oxygen <=> cis-4,5-Dihydroxy-4,5-dihydropyrene
4,5-Dihydroxypyrene + Oxygen <=> Phenanthrene-4,5-dicarboxylate
Phenanthrene-4,5-dicarboxylate <=> Phenanthrene-4-carboxylate + CO2
Phenanthrene-4-carboxylate + Oxygen + NADH + H+ <=> cis-3,4-Phenanthrenedihydrodiol-4-carboxylate + NAD+
cis-3,4-Phenanthrenedihydrodiol-4-carboxylate <=> Phenanthrene-3,4-diol + CO2
Pyrene + Oxygen <=> Pyrene-4,5-oxide + H2O
Pyrene-4,5-oxide + H2O <=> trans-4,5-Dihydroxy-4,5-dihydropyrene
Pyrene + Oxygen <=> Pyrene-1,2-oxide + H2O
1-Hydroxypyrene + Oxygen <=> 1-Hydroxypyrene-6,7-oxide + H2O
1-Hydroxypyrene + Oxygen <=> 1-Hydroxypyrene-7,8-oxide + H2O
1-Hydroxypyrene + S-Adenosyl-L-methionine <=> 1-Methoxypyrene + S-Adenosyl-L-homocysteine
1-Methoxypyrene + Oxygen <=> 1-Methoxypyrene-6,7-oxide + H2O
1-Hydroxy-6-methoxypyrene + CH3-R <=> 1,6-Dimethoxypyrene + R
Benzo[a]pyrene-cis-7,8-dihydrodiol + Oxygen <=> cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate
Benzo[a]pyrene-cis-9,10-dihydrodiol + NAD+ <=> 9,10-Dihydroxybenzo[a]pyrene + NADH + H+
cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate <=> 10-Oxabenzo[def]chrysen-9-one + Formate
C-9 Reduced nonaketamide <=> Nonaketamide monocyclic intermediate + 2 H2O
Nonaketamide monocyclic intermediate <=> Nonaketamide tricyclic intermediate
5a,11a-Dehydrochlortetracycline + NADPH + H+ <=> Chlortetracycline + NADP+
Nonaketamide tricyclic intermediate <=> Pretetramid
2,4-Dichlorotoluene + NADH + Oxygen + H+ <=> 4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-4,5-dihydrodiol + NAD+
4,5-Dihydroxybenzo[a]pyrene + Oxygen <=> 4,5-Chrysenedicarboxylate
4,5-Chrysenedicarboxylate <=> 4-Chrysenecarboxylate + CO2
4,5-Chrysenedicarboxylate <=> 5-Chrysenecarboxylate + CO2
Benzo[a]pyrene + NADH + H+ + Oxygen <=> Benzo[a]pyrene-cis-11,12-dihydrodiol + NAD+
Benzo[a]pyrene + Oxygen <=> Benzo[a]pyrene-11,12-epoxide
Benzo[a]pyrene-11,12-epoxide + H2O <=> Benzo[a]pyrene-trans-11,12-dihydrodiol
4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 4,6-Dichloro-3-methylcatechol + NADH + H+
4,6-Dichloro-3-methylcatechol + Oxygen <=> 3,5-Dichloro-2-methylmuconate
Pyrene-4,5-dione + NADH + H+ <=> 4,5-Dihydroxypyrene + NAD+
4-Methyl-3-oxoadipate-enol-lactone + H2O <=> 4-Methyl-3-oxoadipate
Phthalate + Oxygen + NADH + H+ <=> Phthalate 3,4-cis-dihydrodiol + NAD+
Phthalate 3,4-cis-dihydrodiol + NAD+ <=> 3,4-Dihydroxyphthalate + NADH + H+
2-Amino-4-nitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diaminotoluene + 3 NAD+ + 2 H2O
2,4-Dinitrotoluene + 3 NADH + 3 H+ <=> 2-Amino-4-nitrotoluene + 3 NAD+ + 2 H2O
2,4-Dinitrotoluene + 3 NADH + 3 H+ <=> 4-Amino-2-nitrotoluene + 3 NAD+ + 2 H2O
4-Amino-2-nitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diaminotoluene + 3 NAD+ + 2 H2O
2-Hydroxy-5-methylquinone + NADH + H+ <=> 2,4,5-Trihydroxytoluene + NAD+
2,4,5-Trihydroxytoluene + Oxygen <=> cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate
cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate + H2O <=> (S)-Methylmalonate semialdehyde + Pyruvate
2-Amino-4-nitrotoluene + 3 NADPH + 3 H+ <=> 2,4-Diaminotoluene + 3 NADP+ + 2 H2O
2,4-Dinitrotoluene + 3 NADPH + 3 H+ <=> 2-Amino-4-nitrotoluene + 3 NADP+ + 2 H2O
2,4-Dinitrotoluene + 3 NADPH + 3 H+ <=> 4-Amino-2-nitrotoluene + 3 NADP+ + 2 H2O
4-Amino-2-nitrotoluene + 3 NADPH + 3 H+ <=> 2,4-Diaminotoluene + 3 NADP+ + 2 H2O
(2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesylcistransferase (adding 7 isopentenyl units)
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 3 isopentenyl units)
geranylgeranyl-diphosphate:isopentenyl-diphosphate transferase (adding 2 isopentenyl units)
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 4 isopentenyl units)
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 5 isopentenyl units)
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 7 isopentenyl units)
geranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 7 isopentenyl units)
geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 5 isopentenyl units)
8 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 8 CO2 + 8 CoA
3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] <=> 7,9,12-Octaketide intermediate 1
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,9,12-Decaketide intermediate 1
3,5,7,9,11,13,15,17,19-Nonaoxo-henicosanoyl-[acp] <=> 7,9,12-Decaketide intermediate 4
7,9,12-Octaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Octaketide intermediate 2 + NADP+
7,9,12-Decaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Decaketide intermediate 2 + NADP+
7,9,12-Decaketide intermediate 4 + NADPH + H+ <=> 7,9,12-Decaketide intermediate 5 + NADP+
7,9,12-Octaketide intermediate 2 <=> 7,9,12-Octaketide intermediate 3 + 2 H2O
7,9,12-Decaketide intermediate 2 <=> 7,9,12-Decaketide intermediate 3 + 2 H2O
7,9,12-Decaketide intermediate 5 <=> 7,9,12-Decaketide intermediate 6 + 2 H2O
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,12-Decaketide intermediate 1 + H2O
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 9,14-Decaketide intermediate 1 + 2 H2O
4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate <=> 2-Pyrone-4,6-dicarboxylate + Methanol
4-Aminocatechol + H2O <=> Benzene-1,2,4-triol + Ammonia
Aminohydroquinone + H2O <=> Benzene-1,2,4-triol + Ammonia
UDP-alpha-D-xylose:[protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine 3-alpha-D-xylosyltransferase (configuration-retaining)
UDP-D-galactose + G13053 <=> UDP + G13054
UDP-N-acetyl-D-glucosamine + [Protein]-L-serine <=> UDP + G12573
7,9,12-Octaketide intermediate 3 <=> Octaketide bicyclic intermediate + H2O
Octaketide bicyclic intermediate + NADPH + H+ <=> (S)-Chiral alcohol + NADP+
Octaketide bicyclic intermediate + NADPH + H+ <=> (R)-Chiral alcohol + NADP+
Dihydrokalafungin + NADH + H+ <=> Dihydrokalafungin dihydroquinone form + NAD+
6-Deoxydihydrokalafungin + Reduced FMN + Oxygen <=> Dihydrokalafungin + FMN + H2O
UDP-D-glucose + [Protein]-L-serine <=> UDP + G13051
Methyl-Co(III) corrinoid protein + CoA + CO2 + Reduced ferredoxin <=> Acetyl-CoA + Co(I) corrinoid protein + H2O + Oxidized ferredoxin
UDP-D-galactose + G10770 <=> UDP + G13057
G13057 + H2O <=> N-Acetyl-D-glucosamine + G13058
7,9,12-Decaketide intermediate 3 <=> Deoxynogalonate
7,9,12-Decaketide intermediate 6 <=> 12-Deoxyaklanonic acid
15-Demethoxy-epsilon-rhodomycin + Oxygen + 2 Glutathione <=> beta-Rhodomycin + CO2 + H2O + Glutathione disulfide
7,9,12-Decaketide intermediate 3 <=> UWM6
2,3-Dehydro-UWM6 + L-Isoleucine <=> Jadomycin A + CO2 + H2O
7,12-Decaketide intermediate 1 <=> Decaketide tricyclic intermediate
9,14-Decaketide intermediate 1 <=> Tetracenomycin F2 + Acyl-carrier protein
Selenite + 4 Glutathione + 2 H+ <=> Selenodiglutathione + Glutathione disulfide + 3 H2O
Selenodiglutathione + Glutathione <=> Glutathioselenol + Glutathione disulfide
thiocarboxylated molybdopterin synthase:cyclic pyranopterin phosphate sulfurtransferase
L-isoleucine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin Q1 + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin M1 + H2O + NADP+
Aflatoxin M1 + Oxygen + NADPH + H+ <=> Aflatoxin-M1-8,9-epoxide + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin B1-endo-8,9-epoxide + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin B1-exo-8,9-epoxide + H2O + NADP+
Aflatoxin B1 diol <=> Aflatoxin B1 dialdehyde
Aflatoxin B1 dialdehyde <=> 1,2,3,4-Tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal
Aflatoxin B1 dialdehyde <=> alpha-(1,2-Dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene + H2O + NADP+
trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> (1aalpha,2beta,3alpha,11calpha)-1a,2,3,11c-Tetrahydro-6,11-dimethylbenzo[6,7]phenanthro[3,4-b]oxirene-2,3-diol + H2O + NADP+
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP+
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + Oxygen + NADPH + H+ <=> 1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + Oxygen + NADPH + H+ <=> alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide + UDP
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> NNAL-N-glucuronide + UDP
4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone <=> 4-(Nitrosoamino)-1-(3-pyridinyl)-1-butanone + Formaldehyde
alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol <=> alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol + Formaldehyde
4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone <=> 4-Oxo-1-(3-pyridyl)-1-butanone + N-Nitrosomethanamine
1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol <=> 5-(3-Pyridyl)-2-hydroxytetrahydrofuran + N-Nitrosomethanamine
4-(Nitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O <=> 4-Hydroxy-1-(3-pyridinyl)-1-butanone + Nitrogen + H2O
alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol + H2O <=> 1-(3-Pyridinyl)-1,4-butanediol + Nitrogen + H2O
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7-Hydroxymethyl-12-methylbenz[a]anthracene + H2O + NADP+
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O + NADP+
D-Glucuronate + NAD+ + H2O <=> D-Glucarate + NADH + H+
(9Z)-Octadecenoic acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)
6-Hydroxypseudooxynicotine + 2 H2O <=> 6-Hydroxy-3-succinoylpyridine + Methylamine
4-(6-hydroxypyridin-3-yl)-4-oxobutanoate,NADH:oxygen oxidoreductase (3-hydroxylating, succinate semialdehyde releasing)
(3Z)-phycoerythrobilin:ferredoxin oxidoreductase (from biliverdin IXalpha)
substrate:hydrogen peroxide oxidoreductase (RH-hydroxylating or -epoxidising)
Angiotensin II + H2O <=> Angiotensin (1-7) + L-Phenylalanine
2 Ascorbate + Hydrogen peroxide <=> 2 Monodehydroascorbate + 2 H2O
(+)-germacrene-A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
5-epiaristolochene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (1- and 3-hydroxylating)
germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
N,N-Dihydroxy-L-phenylalanine <=> (E)-Phenylacetaldoxime + CO2 + H2O
N-hydroxy-L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
N,N-Dihydroxy-L-tryptophan <=> Indole-3-acetaldehyde oxime + CO2 + H2O
Cobyrinate + L-Glutamine + ATP + H2O <=> Cobyrinate c-monamide + L-Glutamate + ADP + Orthophosphate
Cobyrinate c-monamide + L-Glutamine + ATP + H2O <=> Cob(II)yrinate a,c diamide + L-Glutamate + ADP + Orthophosphate
pratensein,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming)
beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (24-hydroxylating)
sophoradiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (24-hydroxylating)
dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 2 isopentenyl units)
geranylgeranyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 7 isopentenyl units)
(2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 9-11 isopentenyl units)
CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)2-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase [(2->8) glycosidic bond-forming]
Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP
CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)3-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase [(2->4) glycosidic bond-forming]
4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate:lipid IVA 4-amino-4-deoxy-beta-L-arabinopyranosyltransferase
4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate:KDO2-lipid IVA 4-amino-4-deoxy-beta-L-arabinopyranosyltransferase
4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate:KDO2-lipid A 4-amino-4-deoxy-alpha-L-arabinopyranosyltransferase
Nitric oxide + Azide <=> Nitrous oxide + Nitrogen
Nitric oxide + Ammonia <=> Nitrous oxide + H2O
beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
all-trans-retinyl ester acylhydrolase, 13-cis retinol forming
2,3-didehydroadipoyl-CoA:acetyl-CoA C-didehydroadipoyltransferase (double bond migration)
Phenylacetyl-CoA + H2O <=> Phenylacetic acid + CoA
phosphoenolpyruvate:2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose transferase (phosphate-hydrolysing, 2,7-acetylamino-transfering, 2-carboxy-2-oxoethyl-forming)
Protein C-terminal S-farnesyl-L-cysteine methyl ester <=> Farnesylcysteine
N-Demethyl-desepoxymaytansinol + 2-Methylpropanoyl-CoA <=> N-Demethyl-desepoxyansamitocin P-3 + CoA
N-Demethyl-desepoxyansamitocin P-3 <=> N-Demethylansamitocin P-3
(+)-linalool,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
(-)-linalool,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
eugenol:NADP+ oxidoreductase (coniferyl ester reducing)
eugenol:NADP+ oxidoreductase (coniferyl acetate reducing)
uracil,FMNH2:oxygen oxidoreductase (uracil hydroxylating, ring-opening)
thymine,FMNH2:oxygen oxidoreductase (thymine hydroxylating, ring-opening)
7,8-dihydroneopterin 3'-triphosphate acetaldehyde-lyase (6-carboxy-5,6,7,8-tetrahydropterin and triphosphate-forming)
(2E,6E)-farnesyl diphosphate diphosphate-lyase (cyclizing, beta-sesquiphellandrene-forming)
(Z)-3-Ureidoacrylate peracid + NADH + H+ <=> Ureidoacrylate + NAD+ + H2O
Aminoacrylate + H2O <=> 3-Oxopropanoate + Ammonia
[methyl-Co(III) corrinoid protein]:coenzyme M methyltransferase
L-Lysine + (2R,3R)-3-Methylornithine + ATP <=> (2R,3R)-3-Methylornithinyl-N6-lysine + Products of ATP breakdown
(2R,3R)-3-Methylornithinyl-N6-lysine + NAD+ + H2O <=> (2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine + Ammonia + NADH + H+
(2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine <=> L-Pyrrolysine + H2O
amorpha-4,11-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
N-hydroxy-L-isoleucine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
N,N-Dihydroxy-L-isoleucine <=> (E)-2-Methylbutanal oxime + CO2 + H2O
(E)-2-Methylbutanal oxime <=> (Z)-2-Methylbutanal oxime
N-hydroxy-L-valine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
N,N-Dihydroxy-L-valine <=> (E)-2-Methylpropanal oxime + CO2 + H2O
(E)-2-Methylpropanal oxime <=> (Z)-2-Methylpropanal oxime
(Z)-2-Methylbutanal oxime + NADPH + H+ + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + NADP+ + 2 H2O
(Z)-2-Methylpropanal oxime + NADPH + H+ + Oxygen <=> Acetone cyanohydrin + NADP+ + 2 H2O
flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3',5'-dihydroxylating)
1,8-cineole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-exo-hydroxylating)
Abietinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abieta-7,13-dien-18,18-diol + [Oxidized NADPH---hemoprotein reductase] + H2O
Abieta-7,13-dien-18,18-diol <=> Abietal + H2O
L-Hydroxyarginine <=> Guanidine + (S)-1-Pyrroline-5-carboxylate + H2O
D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase
D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase (glutamine-hydrolyzing)
2,4-Dichloro-2,5-dihydro-5-oxofuran-2-acetate <=> cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid
L-Arginine + Oxygen + NADH + H+ <=> N(omega)-Hydroxyarginine + NAD+ + H2O
2 N(omega)-Hydroxyarginine + NADH + H+ + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + NAD+ + 2 H2O
4-Nitro-6-oxohepta-2,4-dienedioate <=> 2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + Nitrite
acyl-[acyl-carrier protein],reduced-flavodoxin:oxygen oxidoreductase (pimeloyl-[acyl-carrier protein] forming)
beta-Citronellol + NAD+ <=> (R)-(+)-Citronellal + NADH + H+
(-)-Citronellol + NAD+ <=> (S)-(-)-Citronellal + NADH + H+
G00164 + UDP-D-glucuronate <=> G00165 + UDP
G00165 + UDP-N-acetyl-D-glucosamine <=> G13062 + UDP
Sulfite + 3 NADH + 3 H+ <=> Hydrogen sulfide + 3 NAD+ + 3 H2O
L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing
Thiosulfate + Menaquinol <=> HSO3- + Hydrogen sulfide + Menaquinone
Thiosulfate + 5 H2O + 8 Ferricytochrome c <=> 2 Sulfate + 8 Ferrocytochrome c + 10 H+
octanoyl-CoA:malonyl-[acyl-carrier protein] C-heptanoyltransferase (decarboxylating, CoA-forming)
S-Adenosyl-L-methionine + C30 Botryococcene <=> S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene <=> S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene
S-Adenosyl-L-methionine + C30 Botryococcene <=> S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene
S-Adenosyl-L-methionine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene <=> S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene
Dimethyl sulfone + 2 Reduced FMN + 2 Oxygen <=> Methanesulfonic acid + Formaldehyde + 2 FMN + 2 H2O
5-phospho-alpha-D-ribose 1,2-cyclic phosphate 2-phosphohydrolase (alpha-D-ribose 1,5-bisphosphate-forming)
(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (trans-2-enoyl-[acyl-carrier protein]-forming)
2-Oxoglutaryl-CoA + H2O <=> 2-Oxoglutarate + CoA
S-(5-Hydroxy-2-furoyl)-CoA + H2O <=> 2-Oxoglutaryl-CoA
Furfural + H2O + Oxygen <=> 2-Furoate + Hydrogen peroxide
2,5-Furandicarboxylate <=> 2-Furoate + CO2
5-Hydroxymethyl-2-furaldehyde + H2O + Oxygen <=> 5-Hydroxymethyl-2-furoate + Hydrogen peroxide
Furfural + NADH + H+ <=> Furfuryl alcohol + NAD+
5-Hydroxymethyl-2-furaldehyde + NADH + H+ <=> 5-Hydroxymethylfurfuryl alcohol + NAD+
Acetyl-CoA + Tetrahydrosarcinapterin <=> CoA + 5-Methyl-H4SPT + CO
norsolorinic acid anthrone:oxygen 9-oxidoreductase (norsolorinic acid-forming)
malonyl-CoA:hexanoate malonyltransferase (norsolorinic acid anthrone-forming)
Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
Iminoglycine + H2O <=> Glyoxylate + Ammonia
Coniferyl alcohol + Acetyl-CoA <=> Coniferyl acetate + CoA
4-Coumaryl alcohol + Acetyl-CoA <=> Coumaryl acetate + CoA
Sporulenol <=> Tetraprenyl-beta-curcumene + H2O
Formaldehyde + Mycothiol <=> S-(Hydroxymethyl)mycothiol
S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine-[translation elongation factor 2] methyltransferase
11-oxo-beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (30-hydroxylating)
30-hydroxy-11-oxo-beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (30-hydroxylating)
glycyrrhetaldehyde,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (30-hydroxylating)
(1'S)-averantin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5'-hydroxylating)
8-O-methylsterigmatocystin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (aflatoxin-B forming)
8-O-methyldihydrosterigmatocystin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (aflatoxin-B forming)
tryprostatin B,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxytryprostatin B-forming)
GTP 7,8-8,9-dihydrolase (cyclizing, formate-releasing, diphosphate-releasing)
Geranylgeranyl diphosphate + Indoleglycerol phosphate <=> 3-Geranylgeranylindole + D-Glyceraldehyde 3-phosphate + Diphosphate
12-Demethyl-11,12-dehydropaspaline + Oxygen + NADPH + H+ <=> beta-PC-M6 + NADP+ + H2O
beta-PC-M6 + Oxygen + NADPH + H+ <=> 13-Desoxypaxilline + NADP+ + 2 H2O
Paxilline + 2 Dimethylallyl diphosphate <=> 21,22-Diprenylpaxilline + 2 Diphosphate
13-Desoxypaxilline + NADPH + Oxygen + H+ <=> Paspalicine + NADP+ + 2 H2O
Paspalicine + Oxygen + NADPH + H+ <=> Paspalinine + NADP+ + H2O
20,21-Diprenylterpendole I + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitriol + 3 NADP+ + 4 H2O
Lolitrem E + NADPH + Oxygen + H+ <=> Lolitrem B + NADP+ + 2 H2O
Terpendole I + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole I + 2 Diphosphate
Terpendole E + 4 NADPH + 4 Oxygen + 4 H+ <=> 13-Desoxyterpendole I + Formate + 4 NADP+ + 5 H2O
12-Demethyl-11,12-dehydropaspaline + 3 Oxygen + 3 NADPH + 3 H+ <=> Terpendole I + 3 NADP+ + 3 H2O
Terpendole J + NADPH + Oxygen + H+ <=> Terpendole C + NADP+ + 2 H2O
Terpendole C + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole C + 2 Diphosphate
Terpendole J + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole J + 2 Diphosphate
7-Oxoheptanoic acid <=> 7-Mercaptoheptanoic acid
2-Amino-2-deoxy-D-gluconate + Protein N(pi)-phospho-L-histidine <=> D-Glucosaminate-6-phosphate + Protein histidine
S-Sulfo-L-cysteine + Glutaredoxin <=> L-Cysteine + Sulfite + Glutaredoxin disulfide
fumitremorgin C,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha,13alpha-dihydroxyfumitremorgin C-forming)
tryprostatin A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
NDP + H2O <=> Nucleoside 5'-phosphate + Orthophosphate
nucleoside triphosphate phosphohydrolase (nucleoside monophosphoate-forming)
S-adenosyl-L-methionine:L-histidine-[translation elongation factor 2] 2-[(3S)-3-amino-3-carboxypropyl]transferase
(1'S,5'S)-Averufin + NADPH + H+ + Oxygen <=> 1'-Hydroxyversicolorone + NADP+ + H2O
1'-Hydroxyversicolorone + NADPH + H+ + Oxygen <=> Versiconal hemiacetal acetate + NADP+ + H2O
Versicolorone + NADPH + H+ + Oxygen <=> Versiconol acetate + NADP+ + H2O
Versicolorin B + Oxygen + NADPH + H+ <=> Versicolorin A + NADP+ + 2 H2O
(S)-2-Acetolactate + Acceptor <=> Diacetyl + CO2 + Reduced acceptor
dammarenediol-II,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12beta-hydroxylating)
Carbamoyl phosphate + ATP + H2O <=> Diphosphate + O-Carbamoyladenylate + Orthophosphate
kanamycin A:carbamoyl phosphate ligase (AMP,phosphate-forming)
tRNA(Phe)-N1-methylguanine,pyruvate acetaldehyde-lyase [tRNA(Phe)-4-demethylwyosine-forming, decarboxylating, dehydrating]
protopanaxadiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
(2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-beta-chamigrene-forming)
(2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-thujopsene-forming)
D-Galactono-1,5-lactone + H2O <=> D-Galactonate
NAD+ + Histone N6-acetyl-L-lysine + H2O <=> Nicotinamide + Histone-L-lysine + O-Acetyl-ADP-ribose + H+
NAD+ + Protein N6-acetyl-L-lysine + H2O <=> Nicotinamide + Protein lysine + O-Acetyl-ADP-ribose + H+
Prunasin + UDP-glucose <=> Amygdalin + UDP
tRNA containing 6-isopentenyladenosine + Sulfur donor + S-Adenosyl-L-methionine <=> 2-Thio-N6-dimethylallyladenine in tRNA + L-Methionine + 5'-Deoxyadenosine
2-Thio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-methionine <=> 2-Methylthio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-homocysteine
N6-L-Threonylcarbamoyladenine in tRNA + Sulfur donor + S-Adenosyl-L-methionine <=> 2-Thio-N6-L-threonylcarbamoyladenine in tRNA + L-Methionine + 5'-Deoxyadenosine
2-Thio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-methionine <=> 2-Methylthio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-homocysteine
[Ribosomal protein S12]-L-aspartate + Sulfur donor + S-Adenosyl-L-methionine <=> [Ribosomal protein S12]-3-thioaspartate + L-Methionine + 5'-Deoxyadenosine
fumarate CoM:CoB oxidoreductase (succinate forming)
L-Tryptophan + L-Proline + 2 ATP <=> Brevianamide F + 2 AMP + 2 Diphosphate
Pyridoxal phosphate + L-Histidine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine
N-Acetylaspartylglutamate + H2O <=> N-Acetyl-L-aspartate + L-Glutamate
N-Acetylaspartylglutamylglutamate + H2O <=> N-Acetylaspartylglutamate + L-Glutamate
L-Fucono-1,5-lactone + H2O <=> L-Fuconate
2-Dehydro-3-deoxy-L-fuconate + NAD+ <=> 2,4-Diketo-3-deoxy-L-fuconate + NADH + H+
2,4-Diketo-3-deoxy-L-fuconate + H2O <=> (S)-Lactate + Pyruvate
20,21-Diprenylterpendole J + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitrem E + 3 NADP+ + 4 H2O
20,21-Diprenylterpendole C + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitrem B + 3 NADP+ + 4 H2O
5-O-Caffeoylshikimic acid + H2O <=> Caffeate + Shikimate
ADP-5-ethyl-4-methylthiazole-2-carboxylate + H2O <=> 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate + AMP
cis-Dec-3-enoyl-[acp] <=> n-7 Unsaturated acyl-[acyl-carrier protein]
(S)-Lactaldehyde + NAD+ <=> Methylglyoxal + NADH + H+
phylloquinone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxyphylloquinone forming)
(2E,6E)-farnesyl diphosphate lyase (cyclizing, (-)-exo-alpha-bergamotene-forming)
(2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-alpha-santalene-forming)
(2E,6E)-farnesyl diphosphate lyase (cyclizing, (-)-beta-santalene-forming)
(5R)-Carbapen-2-em-3-carboxylate + L-Cysteine <=> C20817 + CO2
2-Amino-2-deoxy-D-gluconate <=> (2Z,4S,5R)-2-Amino-4,5,6-trihydroxyhex-2-enoate + H2O
(4S,5R)-4,5,6-Trihydroxy-2-iminohexanoate + H2O <=> 2-Dehydro-3-deoxy-D-gluconate + Ammonia
2-methyl-3-oxo-3-ureidopropanoate amidohydrolase (urea- and methylmalonate-forming)
dihydromonacolin L acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating)
monacolin L acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
docosahexaenoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (22-hydroxydocosahexaenoate forming)
G00711 + H2O <=> G10008 + N-Acetyl-D-glucosamine
5-Hydroxymethyl-2-furaldehyde + Oxygen <=> Furan-2,5-dicarbaldehyde + Hydrogen peroxide
Furan-2,5-dicarbaldehyde + H2O <=> 5-(Dihydroxymethyl)furan-2-carbaldehyde
5-(Dihydroxymethyl)furan-2-carbaldehyde + Oxygen <=> 5-Formyl-2-furoate + Hydrogen peroxide
5-Formyl-2-furoate + H2O <=> 5-(Dihydroxymethyl)furan-2-carboxylate
5-(Dihydroxymethyl)furan-2-carboxylate + Oxygen <=> 2,5-Furandicarboxylate + Hydrogen peroxide
5 ATP + 3 L-4-Hydroxyphenylglycine + L-Arginine + L-Serine + H2O <=> 5 AMP + 5 Diphosphate + Nocardicin G + L-4-Hydroxyphenylglycyl-L-arginine
Tabtoxin + H2O <=> Tabtoxinine-beta-lactam + L-Threonine
Hyaluronic acid + H2O <=> Hyaluronic acid + G00526
Hydroxylamine + 2 Ferricytochrome c <=> Nitroxyl + 2 Ferrocytochrome c + 2 H+
Nitroxyl + 2 Ferrocytochrome c + Oxygen + H+ <=> Nitrite + 2 Ferricytochrome c + H2O
beta-Amyrin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Erythrodiol + [Oxidized NADPH---hemoprotein reductase] + H2O
Erythrodiol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Oleanolic aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Oleanolic aldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Oleanolic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (28-hydroxylating)
icosanoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (5,6 cis-dehydrogenating)
(5-Formylfuran-3-yl)methyl phosphate + Orthophosphate + 2 H2O <=> 2 D-Glyceraldehyde 3-phosphate
Ammonia + Carboxyphosphate <=> Carbamate + Orthophosphate
Benzoyl-CoA + Reduced acceptor <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Acceptor
malonyl-CoA C-acyl transferase (1,3,6,8-tetrahydroxynaphthalene forming)
5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase (D-ribose 2,5-bisphosphate-forming)
L-Serine + NAD+ <=> 2-Aminomalonate semialdehyde + NADH + H+
2-Oxobutanoate + Thiamin diphosphate <=> 2-(alpha-Hydroxypropyl)thiamine diphosphate + CO2
2-(alpha-Hydroxypropyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> Enzyme N6-(S-propyldihydrolipoyl)lysine + Thiamin diphosphate
oleoyl-CoA,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)
linoleoyl-CoA,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)
(4R)-4-hydroxysphinganine ceramide,ferrocytochrome-b5:oxygen oxidoreductase (fatty acyl 2-hydroxylating)
dihydroceramide,ferrocytochrome-b5:oxygen oxidoreductase (fatty acyl 2-hydroxylating)
(11Z)-hexadec-11-enoyl-CoA,reduced acceptor:oxygen 10,13-allylic oxidase (10E,12E-forming)
(4E)-sphing-4-enine ceramide,ferrocytochrome b5:oxygen oxidoreductase (8,9-trans dehydrogenating)
(4E,8E)-sphinga-4,8-dienine ceramide,ferrocytochrome b5:oxygen oxidoreductase (10,11-trans-dehydrogenating)
(4R)-4-hydroxysphinganine ceramide,ferrocytochrome b5:oxygen oxidoreductase (8,9-trans-dehydrogenating)
(4R)-4-hydroxysphinganine ceramide,ferrocytochrome b5:oxygen oxidoreductase (8,9-cis-dehydrogenating)
D-Arginine + Acceptor <=> Iminoarginine + Reduced acceptor
Iminoarginine + H2O <=> 5-Guanidino-2-oxopentanoate + Ammonia
2-Aminomuconate semialdehyde <=> Picolinic acid + H2O
(S)-Methylmalonate semialdehyde <=> (R)-Methylmalonate semialdehyde
palmitoleoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (12,13 cis-dehydrogenating)
(S)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide
5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + H2O <=> 6-Hydroxypseudooxynicotine
(R)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide
dodecanoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7-hydroxylating)
(3E)-3-[(1R,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + NADH + H+ <=> 3-[(1R,2S,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + NAD+
3-[(1R,2S,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-Phenylalanine <=> L-Dihydroanticapsin + Phenylpyruvate
2,6-Dichloro-p-benzoquinone + NADH + H+ <=> 2,6-Dichlorohydroquinone + NAD+
2,5-Dichloro-p-benzoquinone + NADH + H+ <=> 2,5-Dichlorohydroquinone + NAD+
5-Chloro-2-hydroxy-p-benzoquinone + NADH + H+ <=> 5-Chloro-1,2,4-trihydroxybenzene + NAD+
24-Methylenecholesterol + NADPH + H+ <=> 24-epi-Campesterol + NADP+
7-Chloro-L-tryptophan + Oxygen <=> Monodechloroaminopyrrolnitrin + CO2 + 2 H2O
Monodechloroaminopyrrolnitrin + FADH2 + Cl- + Oxygen + H+ <=> Aminopyrrolnitrin + FAD + 2 H2O
Aminopyrrolnitrin + 2 NADPH + 2 Oxygen + 2 H+ <=> Pyrrolnitrin + 2 NADP+ + 2 H2O
palmitoyl-[acyl-carrier protein],reduced-ferredoxin:oxygen oxidoreductase (4,5 cis-dehydrogenating)
palmitoyl-[acyl-carrier protein],reduced-ferredoxin:oxygen oxidoreductase (6,7 cis-dehydrogenating)
Diploptene + S-Adenosyl-L-methionine + Reduced acceptor <=> Adenosylhopane + L-Methionine + Acceptor
Adenosylhopane + H2O <=> Ribosylhopane + Adenine
Bacteriohopanetetrol + UDP-N-acetyl-alpha-D-glucosamine <=> Bacteriohopanetetrol-acetylglucosamine + UDP
Bacteriohopanetetrol-acetylglucosamine + H2O <=> Bacteriohopanetetrol-glucosamine + Acetate
Bacteriohopanetetrol-glucosamine <=> Bacteriohopanetetrol cyclitol ether
Ribosylhopane + L-Glutamate <=> Aminobacteriohopanetriol + 2-Oxoglutarate
L-Tryptophan + Oxygen <=> IPA imine + Hydrogen peroxide
Chromopyrrolate + 2 Oxygen + 2 NADH + 3 H+ <=> K-252c + 2 CO2 + 3 H2O + 2 NAD+
K-252c + dTDP-L-ristosamine <=> Holyrine A + dTDP
malonyl-CoA:acetyl-CoA malonyltransferase (5-methyl-1-naphthoic acid forming)
malonyl-CoA:acetyl-CoA malonyltransferase (2-hydroxy-5-methyl-1-naphthoic acid forming)
3-(Methylthio)propanoyl-CoA + FAD <=> 3-(Methylthio)acryloyl-CoA + FADH2
2 IPA imine <=> Protodeoxyviolaceinic acid
Deoxyviolaceinic acid + Oxygen <=> Deoxyviolacein + CO2 + H2O
Violaceinic acid + Oxygen <=> Violacein + CO2 + H2O
3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
Aurachin B + H2O <=> 3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
S-adenosyl 3-(methylsulfanyl)propylamine:spermidine 3-aminopropyltransferase [N4-bis(aminopropyl)spermidine synthesizing]
S-adenosyl 3-(methylsulfanyl)propylamine:spermidine 3-aminopropyltransferase (N4-aminopropylspermidine synthesizing)
S-adenosyl 3-(methylsulfanyl)propylamine:N4-aminopropylspermidine 3-aminopropyltransferase [N4-bis(aminopropyl)spermidine synthesizing]
Dibenzothiophene + Reduced FMN + Oxygen <=> Dibenzothiophene-5-oxide + FMN + H2O
Dibenzothiophene-5-oxide + Reduced FMN + Oxygen <=> Dibenzothiophene-5,5-dioxide + FMN + H2O
S-adenosyl-L-methionine:2-[(3S)-3-carboxy-3-aminopropyl]-L-histidine-[translation elongation factor 2] methyltransferase (diphthine methyl ester-[translation elongation factor 2]-forming)
(R,S)-Nicotine + Oxygen <=> N-Methylmyosmine + Hydrogen peroxide
N-Methylmyosmine + H2O <=> Pseudooxynicotine
Pseudooxynicotine + H2O <=> 3-Succinoylpyridine + Methylamine
3-Succinoylpyridine + H2O + Acceptor <=> 6-Hydroxy-3-succinoylpyridine + Reduced acceptor
L-Alanyl-gamma-D-glutamyl-L-lysine + H2O <=> L-Alanyl-D-glutamate + L-Lysine
4-Hydroxyisophthalate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NAD+ + CO2
4-Hydroxyisophthalate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NADP+ + CO2
[prokaryotic ubiquitin-like protein]:[protein]-L-lysine ligase (ADP-forming)
(-)-bursehernin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5'-hydroxylating)
(-)-deoxypodophyllotoxin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
(-)-matairesinol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming)
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine:lipid A in lipopolysaccharide palmitoyltransferase
Pheophorbide a + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Epoxypheophorbide a + 2 Oxidized ferredoxin + H2O
Epoxypheophorbide a + H2O <=> Red chlorophyll catabolite
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NAD+ + 2 H2O <=> L-2-Aminoadipate + NADH + H+
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADP+ + 2 H2O <=> L-2-Aminoadipate + NADPH + H+
Valienone 7-phosphate <=> 1-epi-Valienol 7-phosphate
Valienone 7-phosphate <=> Validone 7-phosphate
1-epi-Valienol 1-phosphate + Nucleoside triphosphate <=> NDP-1-epi-valienol + Diphosphate
Validone 7-phosphate <=> Validamine 7-phosphate
Validamine 7-phosphate + NDP-1-epi-valienol <=> Validoxylamine A 7'-phosphate + NDP
Validoxylamine A 7'-phosphate + H2O <=> Validoxylamine A + Orthophosphate
Validoxylamine A + UDP-glucose <=> Validamycin A + UDP
5-epi-Valiolone 7-phosphate + NADH + H+ <=> 5-epi-Valiolol 7-phosphate + NAD+
5-epi-Valiolol 7-phosphate <=> 1-epi-Valienol 7-phosphate
1,7-Diphospho-1-epi-valienol + Nucleoside triphosphate <=> NDP-1-epi-valienol 7-phosphate + Diphosphate
NDP-1-epi-valienol 7-phosphate + dTDP-4-amino-4,6-dideoxy-D-glucose <=> dTDP-acarviose-7-phosphate
1-epi-Valienol 7-phosphate <=> 1-epi-Valienol 1-phosphate
NDP-1-epi-valienol + 2-Amino-1,5-anhydro-2-deoxyglucitol <=> Salbostatin 6'-phosphate + NDP
Salbostatin 6'-phosphate + H2O <=> Salbostatin + Orthophosphate
Paromamine + S-Adenosyl-L-methionine + Reduced acceptor <=> 4'-Oxolividamine + L-Methionine + 5'-Deoxyadenosine + Acceptor + H2O
Neamine + S-Adenosyl-L-methionine + Reduced acceptor <=> 4'-Oxonebramine + L-Methionine + 5'-Deoxyadenosine + Acceptor + H2O
Paromomycin II <=> 5'''-epi-Lividomycin B
Gentamicin X2 + FAD <=> 6'-Oxogentamicin X2 + FADH2
Antibiotic G-418 + FAD <=> 6'-Oxo-G418 + FADH2
Antibiotic JI-20B <=> Antibiotic JI-20Ba
Cellulose + H2O <=> Cellulose + Cellodextrin
4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> Diphosphate + Thiamin monophosphate + CO2
G13056 + H2O <=> N-Acetyl-D-glucosamine + G10665
G05477 + H2O <=> G10920 + N-Acetyl-D-glucosamine
UDP-D-galactose + Lactosylceramide <=> UDP + iGb3-Cer
UDP-N-acetyl-D-galactosamine + iGb3-Cer <=> UDP + iGb4-Cer
UDP-N-acetyl-D-galactosamine + iGb4-Cer <=> UDP + G02977
ubiquinol:oxygen oxidoreductase (electrogenic, non H+-transporting)
(25S)-26-Hydroxycholest-4-en-3-one + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> (25S)-26-Oxocholest-4-en-3-one + 2 Oxidized ferredoxin + 2 H2O
(25S)-26-Oxocholest-4-en-3-one + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Delta4-Dafachronic acid + 2 Oxidized ferredoxin + H2O
cholest-4-en-3-one,[reduced ferredoxin]:oxygen oxidoreductase [(25S)-3-oxocholest-4-en-26-oate forming]
(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate lyase (cyclic pyranopterin phosphate-forming)
UDP-D-galactose + Paragloboside <=> UDP + IV4Gala-nLc4-Cer
UDP-D-galactose + Globoside <=> UDP + IV4-alpha-Gal-Gb4Cer
UDP-D-galactose + NORint <=> UDP + NOR2 antigen
UDP-N-acetyl-D-galactosamine + Paragloboside <=> UDP + PX2
UDP-N-acetyl-D-galactosamine + IV4-alpha-Gal-Gb4Cer <=> UDP + NORint
3,6,8-Trihydroxy-2-naphthoate + Reduced acceptor + Oxygen <=> 3,6,7,8-Tetrahydroxy-2-naphthoate + Acceptor + H2O
3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate + CoA <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
(S)-scoulerine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase [(S)-nandinine-forming]
UDP-N-acetyl-D-glucosamine + G13027 <=> UDP + G13087
Acetyl-CoA + 3 Malonyl-CoA + Acyl-carrier protein <=> Orsellinate-[acp] + 4 CoA + 3 CO2 + H2O
2-Methoxyorsellinate-[acp] + Iodide <=> 5-Iodo-2-methoxyorsellinate-[acp]
4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin T0 + 5-Iodo-2,3-dimethoxyorsellinate-[acp] <=> Calicheamicin PsAg + Acyl-carrier protein
8 Malonyl-CoA + 7 NADPH + 7 H+ + Acyl-carrier protein <=> 3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] + 8 CoA + 8 CO2 + 6 H2O + 7 NADP+
3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] <=> 1,3,5,7,9,11,13-Pentadecaheptaene + CO2 + Acyl-carrier protein
(E)-4-Hydroxyphenylacetaldehyde oxime <=> (Z)-4-Hydroxyphenylacetaldehyde oxime
malonyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, methylating, 2-methylbutanoate-forming)
Calcidiol + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Calcitriol + 2 Oxidized ferredoxin + H2O
2 Glyphosate + Oxygen <=> 2 1-Aminomethylphosphonic acid + 2 Glyoxylate
2 (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + 2 H2O
Valienone 7-phosphate <=> Valienol 7-phosphate
Valienol 7-phosphate <=> Valienol 1-phosphate
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + H2O <=> 8-Ethyl-12-methylbacteriochlorophyllide d
8,12-Diethyl-3-vinylbacteriochlorophyllide d + H2O <=> 8,12-Diethylbacteriochlorophyllide d
12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + H2O <=> 12-Ethyl-8-propylbacteriochlorophyllide d
12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H2O <=> 12-Ethyl-8-isobutylbacteriochlorophyllide d
Fe-coproporphyrin III:hydrogen peroxide oxidoreductase (decarboxylating)
[Sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine <=> [Sulfur-carrier protein]-Gly-Gly-L-Cys
ATP + 17-(4-Hydroxyphenyl)heptadecanoate <=> Diphosphate + 17-(4-Hydroxyphenyl)heptadecanoyl adenylate
ATP + 19-(4-Hydroxyphenyl)nonadecanoate <=> Diphosphate + 19-(4-Hydroxyphenyl)nonadecanoyl adenylate
6-Hydroxyferuloyl-CoA <=> Scopoletin + CoA
2 (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate + H2O
(1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate <=> (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + H2O
(1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + Oxygen <=> (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate + Hydrogen peroxide + CO2
(1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate + Oxygen <=> 5,10-Dihydrophenazine + Hydrogen peroxide + CO2
5,10-Dihydrophenazine + Oxygen <=> Phenazine + Hydrogen peroxide
5,10-Dihydrophenazine-1,6-dicarboxylate + Oxygen <=> Phenazine-1,6-dicarboxylic acid + Hydrogen peroxide
5,10-Dihydrophenazine-1-carboxylate + Oxygen <=> Phenazine-1-carboxylate + Hydrogen peroxide
Phenazine-1-carboxylate + NADH + Oxygen + H+ <=> 1-Hydroxyphenazine + NAD+ + CO2 + H2O
protoheme,reduced ferredoxin:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
S-adenosyl-L-methionine:cobalt-factor III 17-methyltransferase (ring contracting)
(E)-2-methylbutanal oxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
(E)-2-methylpropanal oxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
ATP + 4-Hydroxybenzoate <=> Diphosphate + 4-Hydroxybenzoyl-adenylate
Ni-sirohydrochlorin a,c-diamide reductive cyclo-ligase (ADP-forming)
(Z)-2-Methylbutanal oxime <=> 2-Methylbutanenitrile + H2O
2-Methylbutanenitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + [Oxidized NADPH---hemoprotein reductase] + H2O
(Z)-2-Methylpropanal oxime <=> Isobutyronitrile + H2O
Isobutyronitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Acetone cyanohydrin + [Oxidized NADPH---hemoprotein reductase] + H2O
acyl-CoA,reduced acceptor:oxygen oxidoreductase (15,16 cis-dehydrogenating)
acyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase [omega(9-4),omega(9-5) cis-dehydrogenating]
L-Polyhomomethionine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> L-N-Hydroxypolyhomomethionine + [Oxidized NADPH---hemoprotein reductase] + H2O
L-N-Hydroxypolyhomomethionine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> L-N,N-Dihydroxypolyhomomethionine + [Oxidized NADPH---hemoprotein reductase] + H2O
L-N,N-Dihydroxypolyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime + CO2 + H2O
(E)-omega-(methylthio)alkananaldoxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
omega-(Methylthio)-(E)-alkanal oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 1-aci-Nitro-omega-(methylthio)alkane + [Oxidized NADPH---hemoprotein reductase] + H2O
1-aci-Nitro-omega-(methylthio)alkane + Glutathione <=> (E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O
ent-sandaracopimaradien-3beta-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (oryzalexin E forming)
ent-sandaracopimaradien-3beta-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (oryzalexin D forming)
chitin, hydrogen-donor:oxygen oxidoreductase (N-acetyl-beta-D-glucosaminyl C1-hydroxylating/C4-dehdrogenating)
4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Methyl-3-n-amyl-pyrrole + ATP <=> Prodigiosin + ADP + Orthophosphate
Dodecanoic acid + Malonyl-CoA + Glycine <=> 4-Keto-2-undecylpyrroline + 2 H2O + 2 CO2 + CoA
Pyrrole-2-carbonyl-[pcp] + Acyl-carrier protein <=> Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Peptidyl-carrier protein
Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Malonyl-CoA + L-Serine <=> 4-Hydroxy-2,2'-bipyrrole-5-methanol + CoA + Acyl-carrier protein + 2 CO2 + H2O
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]
(S)-3-Acetyloctanal + Amino acid <=> 2-Methyl-3-n-amyl-dihydropyrrole + 2-Oxo acid
4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Undecylpyrrole + ATP <=> Undecylprodigiosin + ADP + Orthophosphate
1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate
Protoemetine + Dopamine <=> 7'-O-Dmethylcephaeline + H2O
(S)-N-methylcanadine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (1-hydroxylating)
(S)-1-hydroxy-N-methylcanadine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (13-hydroxylating)
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
(13S,14R)-1,8-Dihydroxy-13-O-acetyl-N-methylcanadine <=> 4'-O-Desmethyl-3-O-acetylpapaveroxine + H+
7-(Dihydroxymethyl)bacteriochlorophyllide c <=> Bacteriochlorophyllide e + H2O
2 L-Arginine + 2 Reduced flavodoxin + 2 Oxygen <=> 2 N(omega)-Hydroxyarginine + 2 Oxidized flavodoxin + 2 H2O
2 N(omega)-Hydroxyarginine + Reduced flavodoxin + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + Oxidized flavodoxin + 2 H2O
(E)-phenylacetaldehyde oxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
phenylacetonitrile,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase [(R)-mandelonitrile-forming]
(E)-indol-3-ylacetaldoxime,[reduced NADPH---hemoprotein reductase],glutathione:oxygen oxidoreductase (oxime-hydroxylating)
Indole-3-acetaldehyde oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Indole-3-acetaldoxime N-oxide + [Oxidized NADPH---hemoprotein reductase] + H2O
Indole-3-acetaldoxime N-oxide + Glutathione <=> S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + H2O
(E)-phenylacetaldehyde oxime,[reduced NADPH---hemoprotein reductase],glutathione:oxygen oxidoreductase (oxime-hydroxylating)
(E)-Phenylacetaldoxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 1-aci-Nitro-2-phenylethane + [Oxidized NADPH---hemoprotein reductase] + H2O
1-aci-Nitro-2-phenylethane + Glutathione <=> S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + H2O
(S)-Norlaudanine + S-Adenosyl-L-methionine <=> (S)-Tetrahydropapaverine + S-Adenosyl-L-homocysteine
cellulose, hydrogen-donor:oxygen oxidoreductase (D-glucosyl C1-hydroxylating)
cellulose, hydrogen-donor:oxygen oxidoreductase (D-glucosyl 4-dehydrogenating)
Norcraugsodine + NADPH + H+ <=> Norbelladine + NADP+
2,4,6/3,5-Pentahydroxycyclohexanone + NAD+ <=> 3-Dehydro-scyllo-inosose + NADH + H+
3-Dehydro-scyllo-inosose + H2O <=> 5-Dehydro-L-gluconate
jasmonoyl-L-amino acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
12-hydroxyjasmonoyl-L-amino acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
12-Hydroxyjasmonoyl-L-amino acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Oxojasmonoyl-L-amino acid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
12-Oxojasmonoyl-L-amino acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Hydroxy-12-oxojasmonoyl-L-amino acid + [Oxidized NADPH---hemoprotein reductase] + H2O
16-methoxytabersonine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating)
tabersonine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating)
2-(cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile, [reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (camalexin-forming)
2-(L-Cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (R)-Dihydrocamalexate + Hydrogen cyanide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(R)-Dihydrocamalexate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Camalexin + CO2 + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
S-(Hercyn-2-yl)-L-cysteine S-oxide + H2O <=> 2-(Hydroxysulfanyl)hercynine + Pyruvate + Ammonia
2-(Hydroxysulfanyl)hercynine + Reduced acceptor <=> Ergothioneine + Acceptor + H2O
4-Hydroxybenzoyl-adenylate + Acyl-carrier protein <=> AMP + 4-Hydroxybenzoyl-[acp]
4 Manganese(2+) + Oxygen + 4 H+ <=> 4 Manganese(3+) + 2 H2O
4 Manganese(3+) + Oxygen + 6 H2O <=> 4 Mn(IV)O2 + 12 H+
2 Ubiquinol <=> 2 Ubiquinone + 4 H+ + 4 e-
Hepatotoxins + Glutathione <=> R-S-Glutathione
Isonicotinoyl radical + NAD+ <=> Isonicotinoyl-NAD adduct
Isonicotinoyl radical + NADP+ <=> Isonicotinoyl-NADP adduct
fatty acid carboxy-lyase (light-dependent, alkane-forming)
17-(4-Hydroxyphenyl)heptadecanoyl adenylate + Acyl-carrier protein <=> AMP + 17-(4-Hydroxyphenyl)heptadecanoyl-[acp]
19-(4-Hydroxyphenyl)nonadecanoyl adenylate + Acyl-carrier protein <=> AMP + 19-(4-Hydroxyphenyl)nonadecanoyl-[acp]
1-(4-Methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O <=> 2-({[(4-Methoxyphenyl)methyl](methyl)amino}methyl)-2-methylpropane-1,3-diol
dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 3 isopentenyl units)
S-Sulfanylglutathione + Oxygen <=> S-Sulfinatoglutathione
S-Sulfinatoglutathione + H2O <=> Glutathione + Sulfite
ornithine lipid,2-oxoglutarate:oxygen oxidoreductase (ester-linked acyl 2-hydroxylase)
ferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11-hydroxyferruginol forming)
S-adenosyl-L-methionine:adenine in U6 snRNA methyltransferase
FMN + Oxygen <=> 8-Demethyl-8-formylriboflavin 5'-phosphate + H2O
8-Demethyl-8-formylriboflavin 5'-phosphate + H2O + Acceptor <=> 8-Carboxy-8-demethylriboflavin 5'-phosphate + Reduced acceptor
L-Glutamate + 8-Carboxy-8-demethylriboflavin 5'-phosphate + H2O + 2 Acceptor <=> 2-Oxoglutarate + 8-Amino-8-demethylriboflavin 5'-phosphate + CO2 + 2 Reduced acceptor
ferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (salviol forming)
beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (maniladiol forming)
beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (daturadiol forming)
ferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (sugiol forming)
11-hydroxysugiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11,20-dihydroxysugiol forming)
9beta-pimara7,15-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (9beta-pimara-7,15-diene-3beta-ol forming)
ent-cassa-12,15-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ent-3beta-hydroxycassa-12,15-dien-2-one forming)
ent-Cassa-12,15-diene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-dien-2beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Cassa-12,15-dien-2beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ent-Cassa-12,15-dien-2-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-3beta-Hydroxycassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Cassa-12,15-dien-2beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-diene-2beta,3beta-diol + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Cassa-12,15-diene-2beta,3beta-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-3beta-Hydroxycassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
11-hydroxyferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11,20-dihydroxyferruginol forming)
sugiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11-hydroxysugiol forming)
11-hydroxyferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11-Hydroxysugiol forming)
(2R,3S,4S)-Leucoanthocyanidin + 2-Oxoglutarate + Oxygen <=> (4S)- 2,3-Dehydroflavan-3,4-diol + Succinate + CO2 + H2O
(4S)- 2,3-Dehydroflavan-3,4-diol + H+ <=> Anthocyanidin with a 3-hydroxy group + H2O
GDP-D-mannose + Triacylated phosphatidyl-myo-inositol dimannoside <=> GDP + Triacylated phosphatidyl-myo-inositol trimannoside
GDP-D-mannose + Tetraacylated phosphatidyl-myo-inositol dimannoside <=> GDP + Tetraacylated phosphatidyl-myo-inositol trimannoside
beta-D-Mannosylphosphodecaprenol + Triacylated phosphatidyl-myo-inositol tetramannoside <=> Decaprenol phosphate + Triacylated phosphatidyl-myo-inositol pentamannoside
beta-D-Mannosylphosphodecaprenol + Tetraacylated phosphatidyl-myo-inositol tetramannoside <=> Decaprenol phosphate + Tetraacylated phosphatidyl-myo-inositol pentamannoside
cucurbitadienol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11-oxocucurbitadienol forming)
Cucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Hydroxycucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + H2O
11-Hydroxycucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Oxocucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
drimenol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (drimendiol forming)
4-Hydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3-Bromo-4-hydroxybenzoate + NADP+ + 2 H2O
3-Bromo-4-hydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 2,4-Dibromophenol + NADP+ + CO2 + 2 H2O
3,4-Dihydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3-Bromo-4,5-dihydroxybenzoate + NADP+ + 2 H2O
3-Bromo-4,5-dihydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3,5-Dibromobenzene-1,2-diol + NADP+ + CO2 + 2 H2O
Pyrrole-2-carbonyl-[pcp] + FADH2 + Cl- + Oxygen <=> 5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Cl- + Oxygen <=> 4,5-Dichloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
cis-3-[2,2-Dichloro-1-(4-chlorophenyl)vinyl]-6-chlorocyclohexa-3,5-diene-1,2-diol + NAD+ <=> 1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene + NADH + H+
Pyrrole-2-carbonyl-[pcp] + FADH2 + Bromide + Oxygen <=> 5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Bromide + Oxygen <=> 4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Bromide + Oxygen <=> 3,4,5-Tribromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
Stearoyl-CoA + NADPH + H+ + Oxygen <=> Oleoyl-CoA + NADP+ + 2 H2O
Anthraniloyl-CoA + 2 Malonyl-CoA <=> 2-Methylquinolin-4-ol + 3 CO2 + 3 CoA
2-Methylquinolin-4-ol + trans,trans-Farnesyl diphosphate <=> Aurachin D + Diphosphate
ATP + L-Proline <=> Diphosphate + (L-Prolyl)adenylate
(L-Prolyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Prolyl-[pcp]
ent-isokaurene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ent-isokaurene-2beta,3beta-diol forming)
ATP + Pyridinium-3,5-biscarboxylic acid mononucleotide <=> Diphosphate + 5-Carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate
5-Carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate + [Protein]-L-cysteine <=> AMP + [Protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine
[Protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [Protein]-dehydroalanine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide
ATP + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide <=> Diphosphate + 1-(5-O-Phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate
1-(5-O-Phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate + [Protein]-L-cysteine <=> AMP + [Protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine
[Protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [Protein]-dehydroalanine + Pyridinium-3,5-bisthiocarboxylate mononucleotide
albendazole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (sulfoxide-forming)
fenbendazole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (sulfoxide-forming)
albendazole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
fenbendazole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4'-hydroxylating)
long-chain fatty acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)
UDP-alpha-D-galactofuranose + Rhamnosyl-N-acetyl-glucosaminyl-decaprenyl diphosphate <=> UDP + Glycolipid 3
UDP-alpha-D-galactofuranose + Glycolipid 3 <=> UDP + Glycolipid 4
UDP-alpha-D-galactofuranose + Glycolipid 4 <=> UDP + Glycolipid 5
Dihydrochanoclavine-I aldehyde + H+ <=> 6,8-Dimethyl-6,7-didehydroergoline + H2O
Chanoclavine-I aldehyde + H+ <=> 6,8-Dimethyl-6,7,8,9-tetradehydroergoline + H2O
Delta9-Tetrahydrocannabinolate <=> Dronabinol + CO2
Cannabidiolic acid <=> Cannabidiol + CO2
carotenoid beta-ring:acceptor oxidoreductase/methyltranferase (phi-ring forming)
carotenoid beta-ring:acceptor oxidoreductase/methyltranferase (chi-ring forming)
sterol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving)
14alpha-Methylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 14alpha-Hydroxymethylsteroid + [Oxidized NADPH---hemoprotein reductase] + H2O
14alpha-Hydroxymethylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 14alpha-Formylsteroid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
14alpha-Formylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Delta14-Steroid + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O
abieta-7,13-dien-18-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating)
Abietal + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abietate + [Oxidized NADPH---hemoprotein reductase] + H2O
1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3-phosphate + Orthophosphate
germacra-1(10),4,11(13)-trien-12-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
germacra-1(10),4,11(13)-trien-12-al,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
6alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Costunolide + H2O
4-Cresol + 2 Oxidized azurin + H2O <=> p-Hydroxybenzyl alcohol + 2 Reduced azurin + 2 H+
p-Hydroxybenzyl alcohol + 2 Oxidized azurin <=> 4-Hydroxybenzaldehyde + 2 Reduced azurin + 2 H+
17-O-Acetylnorajmaline + S-Adenosyl-L-methionine <=> 17-O-Acetylajmaline + S-Adenosyl-L-homocysteine
(9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid + H2O <=> 9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid
9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid + NADPH + H+ <=> 9-Hydroxy-12-oxo-15(Z)-octadecenoic acid + NADP+
N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + Ammonia <=> 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + H2O
(+)-pinoresinol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (cyclizing)
(+)-piperitol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (cyclizing)
(11Z,14Z)-icosadienoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (8,9 cis-dehydrogenating)
cis-trans-Nepetalactol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Iridotrial + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate:lipid IVB 4-amino-4-deoxy-L-arabinopyranosyltransferase
KDO2-lipid-A,2-oxoglutarate:oxygen oxidoreductase (ester-linked acyl 2-hydroxylase)
flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating)
fraxetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5-hydroxylating)
dolabradiene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3beta-hydroxy-15,16-epoxydolabrene-forming)
15,16-epoxydolabrene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3beta-hydroxy-15,16-epoxydolabrene-forming)
(S)-beta-macrocarpene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (zealexin A1-forming)
(+)-cis,trans-nepetalactol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
indole-3-carbonyl nitrile,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
very-long-chain acyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (omega9,omega8-cis-dehydrogenating)
7-deoxyloganetic alcohol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8beta-hydroxylating)
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
6alpha,8beta-Dihydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Eupatolide + H2O
germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8alpha-hydroxylating)
8alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate <=> 8-epi-Inunolide + H2O
flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (flavone-forming)
liquiritigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7,4'-dihydroxyflavone-forming)
naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (apigenin-forming)
eriodictyol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (luteolin-forming)
Tetrahydroalstonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Alstonine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O + 2 H+
G13087 + UDP-N-acetyl-D-galactosamine <=> O-mannose core M3 + UDP
O-mannose core M3 + ATP <=> Phospho-core M3 + ADP
Phospho-core M3 + CDP-ribitol <=> G13093 + CMP
G13095 + UDP-D-glucuronate <=> G13096 + UDP
G13097 + UDP-D-glucuronate <=> G13098 + UDP
o-Methoxyphenol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Catechol + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O
2,4-Dihydroxycinnamoyl-CoA <=> Umbelliferone + CoA
G10558 + UDP-N-acetyl-D-glucosamine <=> G13127 + UDP
sterol,reduced ferredoxin:oxygen oxidoreductase (14-methyl cleaving)
14alpha-Methylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 14alpha-Hydroxymethylsteroid + 2 Oxidized ferredoxin + H2O
14alpha-Hydroxymethylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 14alpha-Formylsteroid + 2 Oxidized ferredoxin + 2 H2O
14alpha-Formylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Delta14-Steroid + Formate + 2 Oxidized ferredoxin + H2O
lanosterol,reduced ferredoxin:oxygen oxidoreductase (14-methyl cleaving)
Luteothin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> (7R)-7-Hydroxyluteothin + 2 Oxidized ferredoxin + H2O
(7R)-7-Hydroxyluteothin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Aureothin + 2 Oxidized ferredoxin + 2 H2O
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, NADH)
Urea-1,3-dicarboxylate <=> Urea-1-carboxylate + CO2
G00146 + Dolichyl phosphate D-mannose <=> G13128 + Dolichyl phosphate
G13128 + Phosphatidylethanolamine <=> G00148 + 1,2-Diacyl-sn-glycerol
N3-Fumaroyl-L-2,3-diaminopropanoate + L-Glutamine + ATP + H2O <=> 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Glutamate + ADP + Orthophosphate
D-Ornithine + Citrate + ATP <=> N5-Citryl-D-ornithine + AMP + Diphosphate
N5-Citryl-D-ornithine + Citrate + ATP <=> Staphyloferrin A + AMP + Diphosphate
Squalene + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (S)-2,3-Epoxysqualene + 2 Ferricytochrome b5 + H2O
beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (16alpha-hydroxylating)
(S)-methylmalonyl-CoA:palmitoyl-[(hydroxy)phthioceranic acid synthase] methylmalonyltransferase (phthioceranyl-[(hydroxy)phthioceranic acid synthase]-forming)
2-Amino-4-chloro-4-pentenoic acid <=> L-Propargylglycine + Cl- + H+
L-Propargylglycine + L-Glutamate <=> gamma-L-Glutamyl-L-propargylglycine
L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + H2O <=> L-beta-Ethynylserine + L-Glutamate
L-Tryptophan + L-Phenylalanine <=> Cyclo(L-Trp-L-Phe)
(9Z,12Z)-octadeca-9,12-dienoyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (15,16 cis-dehydrogenating)
Anthranilate + L-Tryptophan + L-Alanine + 3 ATP <=> Fumiquinazoline F + 3 AMP + 3 Diphosphate + H2O
Fumiquinazoline F + 3 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Fumiquinazoline F-indoline-2',3'-diol + 3 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Fumiquinazoline F-indoline-2',3'-diol + L-Alanine + ATP <=> Fumiquinazoline A + AMP + Diphosphate + H2O
Fumiquinazoline A + Oxygen <=> Fumiquinazoline C + Hydrogen peroxide
[lipoyl-carrier protein E2]-N6-(octanoyl)-L-lysine:[Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster sulfurtransferase
[glycine cleavage system H]-N6-octanoyl-L-lysine:[Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster sulfurtransferase
[glycine cleavage system H]-N6-octanoyl-L-lysine:[lipoyl-carrier protein E2]-L-lysine octanoyltransferase
[glycine cleavage system H]-N6-lipoyl-L-lysine:[lipoyl-carrier protein]-L-lysine lipoyltransferase
[lipoyl-carrier protein E2]-L-lysine:octanoate ligase (AMP-forming)
[glycine cleavage system H]-N6-[(R)-dihydrolipoyl]-L-lysine:[Lipoyl-carrier protein E2]-L-lysine dihydrolipoyltransferase
[glycine cleavage system H]-L-lysine:(R)-lipoate ligase (AMP-forming)
ATP + Dihydrolipoate <=> Dihydrolipoyl-AMP + Diphosphate
Dihydrolipoyl-AMP + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP + 2 H+
L-Tryptophan + L-Histidine <=> Histidyltryptophyldiketopiperazine
Histidyltryptophyldiketopiperazine + Dimethylallyl diphosphate <=> Roquefortine D + Diphosphate
Dehydrohistidyltryptophyldiketopiperazine + Dimethylallyl diphosphate <=> Roquefortine C + Diphosphate
Roquefortine C + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Glandicoline A + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Glandicoline A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glandicoline B + [Oxidized NADPH---hemoprotein reductase] + H2O
Glandicoline B + S-Adenosyl-L-methionine <=> Meleagrin + S-Adenosyl-L-homocysteine
Roquefortine C + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N1-Hydroxy-roquefortine C + [Oxidized NADPH---hemoprotein reductase] + H2O
N1-Hydroxy-roquefortine C + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Roquefortine L + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Roquefortine L + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glandicoline B + [Oxidized NADPH---hemoprotein reductase] + H2O
N1-Hydroxy-roquefortine C + S-Adenosyl-L-methionine <=> Roquefortine F + S-Adenosyl-L-homocysteine
Roquefortine F + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Neoxaline + [Oxidized NADPH---hemoprotein reductase] + H2O
[lipoyl-carrier protein E2]-L-lysine:(R)-lipoate ligase (AMP-forming)
Lipoyl-AMP + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP
Fe-coproporphyrin III + Hydrogen peroxide <=> Harderoheme III + CO2 + 2 H2O
Harderoheme III + Hydrogen peroxide <=> Heme + CO2 + 2 H2O
Bilirubin + Oxidised coenzyme F420-(gamma-Glu)n <=> Biliverdin + Reduced coenzyme F420-(gamma-Glu)n
UDP-D-glucuronate + T antigen <=> UDP + Glucuronylated core 1 glycans (linear)
2-Hydroxyethylphosphonate + CTP <=> Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Diphosphate
Cytidine 5'-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + H2O <=> (S)-2-Hydroxypropylphosphonate + CMP
Indole-3-acetate + 2-Oxoglutarate + Oxygen <=> 2-Oxoindole-3-acetate + Succinate + CO2
(2E,6E)-farnesyl diphosphate 10-C-methyltransferase (cyclyzing, pre-sodorifen diphosphate producing)
Dibenzothiophene-5,5-dioxide + FMN-N5-peroxide <=> 2'-Hydroxybiphenyl-2-sulfinate + FMN-N5-oxide
FMN-N5-oxide + NADH <=> FMN + H2O + NAD+ + H+
Uracil + FMN-N5-peroxide <=> Ureidoacrylate + FMN-N5-oxide
Thymine + FMN-N5-peroxide <=> Methylureidoacrylate + FMN-N5-oxide
Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-D-glucose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose
chenodeoxycholate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating)
UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+
UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + D-Alanine <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose + H2O
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose + H2O <=> 2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + UDP
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + Acetyl-CoA <=> UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idose + CoA
5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + CTP <=> CMP-5-N-acetyl-7-N-(D-alanyl)-legionaminic acid + Diphosphate
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-gulose + H2O <=> 2,4-Diacetamido-2,4,6-trideoxy-beta-L-gulose + UDP
2,4-Diacetamido-2,4,6-trideoxy-beta-L-gulose + Phosphoenolpyruvate + H2O <=> 5,7-Diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid + Orthophosphate
2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> 5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + Orthophosphate
CTP + 5,7-Diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid <=> CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid + Diphosphate
ATP + L-Arginine <=> Diphosphate + (L-Arginyl)adenylate
(L-Arginyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Arginyl-[pcp]
ATP + 3,4-Dihydroxybenzoate + Aryl-carrier protein <=> AMP + Diphosphate + 3,4-Dihydroxybenzoyl-[aryl-carrier protein]
ATP + 3,4-Dihydroxybenzoate <=> Diphosphate + (3,4-Dihydroxybenzoyl)adenylate
(3,4-Dihydroxybenzoyl)adenylate + Aryl-carrier protein <=> AMP + 3,4-Dihydroxybenzoyl-[aryl-carrier protein]
2-hydroxy fatty acid:oxygen oxidoreductase (CO2,H2O-forming)
UDP-N-acetyl-D-galactosaminuronic acid + ATP + L-Glutamine + H2O <=> UDP-2-acetamido-2-deoxy-alpha-D-galacturonamide + AMP + L-Glutamate + Diphosphate
Spermidine + Citrate + ATP <=> N-Citryl-spermidine + AMP + Diphosphate
N-Citryl-spermidine + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine + Aryl-carrier protein
N-Citryl-spermidine + Spermidine + ATP <=> N8,N'8-Citryl-bis(spermidine) + AMP + Diphosphate
N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine + Spermidine + ATP <=> N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + AMP + Diphosphate
N8,N'8-Citryl-bis(spermidine) + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + Aryl-carrier protein
N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> Petrobactin + Aryl-carrier protein
UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-mannose + NADP+
Protoporphyrinogen IX + 3 Acceptor <=> Protoporphyrin + 3 Reduced acceptor
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate <=> UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + 2-Oxoglutarate
Methylureidoacrylate + H2O <=> Methylaminoacrylate + Carbamate
thiocyanate:cytochrome c oxidoreductase (cyanate and sulfur-forming)
exo (1->2)-beta-D-glucooligosaccharide sophorohydrolase (non-reducing end)
UDP-alpha-D-xylose:[EGF-like domain protein]-3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine 3-alpha-D-xylosyltransferase (configuration-retaining)
Neryl diphosphate + Isopentenyl diphosphate <=> Diphosphate + (2Z,6Z)-Farnesyl diphosphate
(2Z,6Z)-Farnesyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Nerylneryl diphosphate
abieta-8,11,13-triene,[reduced NADPH---hemoprotein reductase]:oxygen 12-oxidoreductase (ferruginol-forming)
2-Polyprenyl-6-methoxyphenol + Oxygen <=> 2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + H2O
Tryptamine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Serotonin + [Oxidized NADPH---hemoprotein reductase] + H2O
3 Malonyl-CoA + 5 Methylmalonyl-CoA + 7 NADPH + 7 H+ <=> Protomycinolide IV + 8 CoA + 8 CO2 + 4 H2O + 7 NADP+
3-Oxo-Delta1-steroid + H2O <=> 1-Hydroxy-3-oxo-steroid
1-Hydroxy-3-oxo-steroid + Acceptor <=> Steroid 1,3-dione + Reduced acceptor
Heme I + Acceptor + H2O <=> Hydroxyheme I + Reduced acceptor
3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + Oxygen <=> 5-[(4-Hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + Hydrogen peroxide
5-[(4-Hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O <=> 5-[(4-Hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + Ammonia
Mercaptopyruvate + [Protein]-L-cysteine <=> Pyruvate + [Protein]-S-sulfanyl-L-cysteine
[Protein]-S-sulfanyl-L-cysteine + Thioredoxin <=> Hydrogen sulfide + [Protein]-L-cysteine + Thioredoxin disulfide
[Glycine cleavage system H]-N6-octanoyl-L-lysine <=> Dihydrolipoylprotein
3-Hydroxy-L-kynurenine + Glyoxylate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + Glycine
Dihydro-heme d1 + Acceptor <=> Heme d1 + Reduced acceptor
sn-Glycerol 1-phosphate + all-trans-Heptaprenyl diphosphate <=> Heptaprenylglyceryl phosphate + Diphosphate
Heptaprenylglyceryl phosphate + H2O <=> Heptaprenylglycerol + Orthophosphate
Heptaprenylglycerol + 2 Acetyl-CoA <=> Diacetylheptaprenylglycerol + 2 CoA
Phosphatidylethanolamine + G13044 <=> 1,2-Diacyl-sn-glycerol + G13152
Allantoate + Orthophosphate <=> (S)-Ureidoglycine + Carbamoyl phosphate
CMP-N-acetylneuraminate + T antigen <=> CMP + G10794
UDP-N-acetyl-D-glucosamine + T antigen <=> UDP + G13153
Nopaline + H2O + Acceptor <=> L-Arginine + 2-Oxoglutarate + Reduced acceptor
Octopine + H2O + Acceptor <=> L-Arginine + Pyruvate + Reduced acceptor
Bacterioruberin <=> Monoanhydrobacterioruberin + H2O
Monoanhydrobacterioruberin <=> Bisanhydrobacterioruberin + H2O
ultra-long-chain fatty acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)
decanoyl-[acyl-carrier protein],reduced ferredoxin:oxygen oxidoreductase (9,10-dehydrogenating)
Decanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Dec-9-enoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O
Dec-9-enoyl-[acyl-carrier protein] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Dec-9-ynoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O
Coenzyme F420-0 + FMN <=> Dehydro coenzyme F420-0 + Reduced FMN
ATP + Glycine <=> Diphosphate + Glycyl-AMP
Glycyl-AMP + Peptidyl-carrier protein <=> AMP + Glycyl-[peptidyl-carrier protein]
C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-L-tyrosine L-tyrosine-carboxylyase
ATP + L-Alanine <=> Diphosphate + (L-Alanyl)adenylate
(L-Alanyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Alanyl-[peptidyl-carrier protein]
ATP + L-Glutamate <=> Diphosphate + (L-Glutamyl)adenylate
(L-Glutamyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Glutamyl-[peptidyl-carrier protein]
C-terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one lyase (C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol-forming)
S-Methyl-1-thio-D-xylulose 5-phosphate + Reduced acceptor <=> Methanethiol + 1-Deoxy-D-xylulose 5-phosphate + Acceptor
Reduced FMN + Oxygen <=> FMN-N5-peroxide
L-Tryptophan <=> Indole + Dehydroalanine
ATP + L-Cysteine <=> Diphosphate + (L-Cysteinyl)adenylate
(L-Cysteinyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Cysteinyl-protein
fatty acid:oxygen 2-oxidoreductase [(2R)-2-hydroperoxyfatty acid-forming]
ATP + L-Threonine <=> Diphosphate + (L-Threonyl)adenylate
(L-Threonyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Threonyl-[L-threonyl-carrier protein]
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 2(R)-HPOT
(2,3-Dihydroxybenzoyl)adenylate + Aryl-carrier protein <=> AMP + 2,3-Dihydroxybenzoyl-[aryl-carrier protein]
primary alkyl sulfate ester, 2-oxoglutarate:oxygen oxidoreductase (sulfate-hydrolyzing)
ATP + L-Serine <=> Diphosphate + (L-Seryl)adenylate
(L-Seryl)adenylate + Peptidyl-carrier protein <=> AMP + L-Seryl-[peptidyl-carrier protein]
ATP + L-Tryptophan <=> Diphosphate + (L-Tryptophyl)adenylate
(L-Tryptophyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Tryptophyl-[peptidyl-carrier protein]
glycine betaine:[Co(I) glycine betaine-specific corrinoid protein] Co-methyltransferase
S-adenosyl-L-methionine:[methyl coenzyme M reductase]-L-arginine C-5-(S)-methyltransferase
3-amino-5-hydroxybenzoate:[acyl carrier protein] ligase (AMP-forming)
primary alkyl sulfate ester sulfohydrolase
branched primary-alkyl sulfate ester sulfohydrolase
2-hydroxy-3-methyl fatty-CoA formyl-CoA lyase (2-methyl branched fatty aldehyde-forming)
(2R)-2-Hydroxy-long-chain fatty acyl-CoA <=> Long-chain fatty aldehyde + Formyl-CoA
C-terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one hydrolyase
(Salicyl)adenylate + Peptidyl-carrier protein <=> AMP + Salicyl-[peptidyl-carrier protein]