Polyphosphate + n H2O <=> (n+1) Oligophosphate
16 ATP + 16 H2O + 8 Reduced ferredoxin <=> 8 e- + 16 Orthophosphate + 16 ADP + 8 Oxidized ferredoxin
Diphosphate + H2O <=> 2 Orthophosphate
Urea-1-carboxylate + H2O <=> 2 CO2 + 2 Ammonia
2-Acetolactate + CO2 <=> 2 Pyruvate
Parapyruvate <=> 2 Pyruvate
2 Hydrogen peroxide <=> Oxygen + 2 H2O
alpha,alpha-Trehalose + H2O <=> 2 D-Glucose
2 Manganese(2+) + Hydrogen peroxide + 2 H+ <=> 2 Manganese(3+) + 2 H2O
2 GTP <=> Diphosphate + P1,P4-Bis(5'-guanosyl) tetraphosphate
2 Glyoxylate <=> 2-Hydroxy-3-oxopropanoate + CO2
Pyruvate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + CO2
2 Sucrose <=> D-Glucose + 1F-beta-D-Fructosylsucrose
Hydrogen peroxide + 2 Ferrocytochrome c <=> 2 Ferricytochrome c + 2 H2O
2 Putrescine <=> sym-Homospermidine + Ammonia
2 Reduced ferredoxin + 2 H+ <=> Hydrogen + 2 Oxidized ferredoxin
2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin + 2 H+
Chitobiose + H2O <=> 2 N-Acetyl-D-glucosamine
2 Hydroxylamine + 2 NAD+ <=> Hyponitrite + 2 NADH + 2 H+
D-Ribulose 1,5-bisphosphate + CO2 + H2O <=> 2 3-Phospho-D-glycerate
Ethylnitronate + Oxygen + Reduced FMN <=> Acetaldehyde + Nitrite + FMN + H2O
Cellobiose + H2O <=> 2 beta-D-Glucose
Benzoin <=> 2 Benzaldehyde
Maltose + H2O <=> 2 D-Glucose
2 Thiosulfate + 2 Ferricytochrome c <=> Tetrathionate + 2 Ferrocytochrome c
Oxygen + 2 L-Tyrosine <=> 2 3,4-Dihydroxy-L-phenylalanine
beta-Carotene + Oxygen <=> 2 Retinal
Thiamine + Oxygen <=> Hydrogen peroxide + Thiamine aldehyde
Cyclobutadipyrimidine <=> 2 Pyrimidine 5'-deoxynucleotide
2 5-Aminolevulinate <=> Porphobilinogen + 2 H2O
2 Propanal <=> 4-Hydroxyhexan-3-one
2 Raffinose <=> Lychnose + Sucrose
2 Long-chain alcohol + Oxygen <=> 2 Long-chain aldehyde + 2 H2O
2 3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> 2 4-Hydroxyphenylacetate + 2 CO2
1,2-Bis(4-hydroxy-3-methoxyphenyl)ethylene + Oxygen <=> 2 4-Hydroxy-3-methoxy-benzaldehyde
2 Columbamine + Oxygen <=> 2 Berberine + 2 H2O
Oxygen + 2 3,4-Dihydroxy-L-phenylalanine <=> 2 Dopaquinone + 2 H2O
Oxygen + 6-Hydroxynicotinate + Reduced acceptor <=> 2,5-Dihydroxypyridine + CO2 + Acceptor + H2O
(R)-3-((R)-3-Hydroxybutanoyloxy)butanoate + H2O <=> 2 (R)-3-Hydroxybutanoate
2 1-O-Galloyl-beta-D-glucose <=> D-Glucose + 1-O,6-O-Digalloyl-beta-D-glucose
Hydrogen peroxide + Alkane + Hydrochloric acid <=> RCl + 2 H2O
Digallate + H2O <=> 2 Gallate
Lecanoric acid + H2O <=> 2 Orsellinate
2 Inosine + Oxygen <=> 2 5'-Oxoinosine + 2 H2O
Dinucleotide + H2O <=> 2 Mononucleotide
Oxygen + 2 R'C(R)SH <=> R'C(R)S-S(R)CR' + Hydrogen peroxide
Oxygen + 2 Catechol <=> 2 o-Benzoquinone + 2 H2O
N-(6-Aminohexanoyl)-6-aminohexanoate + H2O <=> 2 6-Aminohexanoate
Oxygen + 2 Sulochrin <=> 2 (+)-Bisdechlorogeodin + 2 H2O
Oxygen + 2 Sulochrin <=> 2 (-)-Bisdechlorogeodin + 2 H2O
2 Bilirubin-glucuronoside <=> Bilirubin + Bilirubin beta-diglucuronide
2 1-O-Sinapoyl-beta-D-glucose <=> 1,2-Bis-O-sinapoyl-beta-D-glucose + D-Glucose
2 6,7-Dimethyl-8-(D-ribityl)lumazine <=> Riboflavin + 5-Amino-6-(1-D-ribitylamino)uracil
2 e- + 2 H+ <=> Hydrogen
Oxygen + 2 Ascorbate <=> 2 Dehydroascorbate + 2 H2O
Hydantoin-5-propionate + Hydrogen peroxide <=> 4-Imidazolone-5-propanoate + Oxygen + H2O
2 D-Urobilinogen + Oxygen <=> 2 D-Urobilin + 2 H2O
Thiamine aldehyde + Oxygen + H2O <=> Hydrogen peroxide + Thiamine acetic acid
Prostaglandin H2 + Acceptor + H2O <=> Prostaglandin G2 + Reduced acceptor
4 2-Aminophenol + 3 Oxygen <=> 2 2-Aminophenoxazin-3-one + 6 H2O
3 S-Adenosyl-L-methionine <=> 3 5'-Methylthioadenosine + Nicotianamine
4 ATP + 2 Phosphorylase b <=> 4 ADP + Phosphorylase a
Phosphorylase a + 4 H2O <=> 2 Phosphorylase b + 4 Orthophosphate
Oxygen + 4 Fe2+ + 4 H+ <=> 4 Fe3+ + 2 H2O
4 Catechol + 3 Oxygen <=> 6 H2O + 2 Dibenzo[1,4]dioxin-2,3-dione
Oxygen + 4 Ferrocytochrome c + 4 H+ <=> 4 Ferricytochrome c + 2 H2O
Oxygen + 4 Ferrocytochrome c2 <=> 4 Ferricytochrome c2 + 2 H2O
Oxygen + 4 Benzenediol <=> 4 Semiquinone + 2 H2O
4 Porphobilinogen + H2O <=> Hydroxymethylbilane + 4 Ammonia
ATP + 2 H2O <=> AMP + 2 Orthophosphate
ATP + H2O <=> ADP + Orthophosphate
ATP + H2O <=> AMP + Diphosphate
ATP + H2O <=> ITP + Ammonia
ATP <=> 3',5'-Cyclic AMP + Diphosphate
Hydrogen peroxide + NADH + H+ <=> NAD+ + 2 H2O
NAD+ + 2 CoA <=> CoA-disulfide + NADH + H+
NAD+ + 2 Fe2+ <=> NADH + H+ + 2 Fe3+
2 L-Glutamate + NAD+ <=> L-Glutamine + 2-Oxoglutarate + NADH + H+
2 Glutathione + NAD+ <=> Glutathione disulfide + NADH + H+
NAD+ + 2 Ascorbate <=> NADH + 2 Monodehydroascorbate + H+
Cob(II)alamin <=> Aquacob(III)alamin
NAD+ + 2 Cob(I)alamin <=> NADH + H+ + 2 Cob(II)alamin
NADH + 2 Ferricytochrome b5 <=> NAD+ + 2 Ferrocytochrome b5 + H+
NADH + 2 Ferrileghemoglobin <=> NAD+ + 2 Ferroleghemoglobin + H+
NAD+ + H2O <=> Nicotinamide + ADP-ribose
NAD+ + H2O <=> AMP + Nicotinamide D-ribonucleotide
ATP + NAD+ <=> ADP + NADP+
ATP + NADH <=> ADP + NADPH
NADPH + 2 Ferricytochrome <=> NADP+ + 2 Ferrocytochrome + H+
NADPH + 2 Ferricytochrome c2 <=> NADP+ + 2 Ferrocytochrome c2 + H+
NADPH + 2 Ferrileghemoglobin <=> NADP+ + 2 Ferroleghemoglobin + H+
NADPH + 2 N(omega)-Hydroxyarginine + 2 Oxygen + H+ <=> NADP+ + 2 Nitric oxide + 2 L-Citrulline + 2 H2O
NADPH + NAD+ <=> NADP+ + NADH
Hydrogen peroxide + NADPH + H+ <=> NADP+ + 2 H2O
2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+
2 Glutathione + NADP+ <=> Glutathione disulfide + NADPH + H+
NADP+ + H2O <=> Orthophosphate + NAD+
NADP+ + Nicotinate <=> Nicotinamide + Nicotinic acid adenine dinucleotide phosphate
Oxygen + 2 Glutathione <=> Glutathione disulfide + Hydrogen peroxide
ADP + H2O <=> AMP + Orthophosphate
ADP + H2O <=> IDP + Ammonia
ATP + ADP <=> ADP + ATP
P1,P4-Bis(5'-adenosyl)tetraphosphate + H2O <=> 2 ADP
ADP + ATP <=> Orthophosphate + P1,P4-Bis(5'-adenosyl)tetraphosphate
ATP + AMP <=> 2 ADP
Adenosine tetraphosphate + H2O <=> ATP + Orthophosphate
ATP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> ADP + Orthophosphate + NADH
ATP + Dephospho-CoA <=> ADP + CoA
Urea + H2O <=> CO2 + 2 Ammonia
Carbonic acid <=> CO2 + H2O
Formate + NADP+ <=> CO2 + NADPH + H+
Peptide + H2O <=> L-Proline + Peptide
ATP + Nicotinamide D-ribonucleotide <=> Diphosphate + NAD+
Triphosphate + H2O <=> Diphosphate + Orthophosphate
2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP
2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ADP <=> 5-Hydroxymethyldeoxycytidylate + ATP
ATP + Ammonia <=> ADP + Phosphoramidate
Ammonia + NAD+ + H2O <=> Hydroxylamine + NADH + H+
alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+
alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+
Ammonia + Oxygen + Ubiquinol <=> Hydroxylamine + H2O + Ubiquinone
2 ATP + Ammonia + CO2 + H2O <=> 2 ADP + Orthophosphate + Carbamoyl phosphate
ATP + Ammonia + HCO3- <=> ADP + Carbamoyl phosphate + H2O
Hydrogen cyanide + 2 H2O <=> Ammonia + Formate
Hydrazine + 2 e- + 2 H+ <=> 2 Ammonia
UDP + H2O <=> UMP + Orthophosphate
ATP + UDP <=> ADP + UTP
UTP + AMP <=> UDP + ADP
ATP + UMP <=> ADP + UDP
UTP + H2O <=> UDP + Orthophosphate
FAD + H2O <=> AMP + FMN
ATP + FMN <=> Diphosphate + FAD
ATP + Protein <=> ADP + Phosphoprotein
Phosphoprotein + H2O <=> Protein + Orthophosphate
Protein <=> L-Alanyl-tRNA
Protein <=> L-Leucyl-tRNA
L-Arginyl-tRNA(Arg) <=> Protein-L-arginine
Protein <=> L-Valyl-tRNA(Val)
Protein <=> L-Glutamyl-tRNA(Glu)
Protein <=> L-Isoleucyl-tRNA(Ile)
Protein <=> Selenomethionyl-tRNA(Met)
Pyridoxal phosphate + H2O <=> Pyridoxal + Orthophosphate
ATP + Pyridoxal <=> ADP + Pyridoxal phosphate
S-Adenosyl-L-methionine + H2O <=> 5'-Methylthioadenosine + L-Homoserine
Orthophosphate + Diphosphate + S-Adenosyl-L-methionine <=> ATP + L-Methionine + H2O
S-Adenosyl-L-methionine + H+ <=> S-Adenosylmethioninamine + CO2
S-Adenosyl-L-methionine <=> 1-Aminocyclopropane-1-carboxylate + 5'-Methylthioadenosine
S-Adenosyl-L-methionine <=> 5'-Methylthioadenosine + Homoserine lactone
AMP + H2O <=> IMP + Ammonia
AMP + H2O <=> Adenine + D-Ribose 5-phosphate
AMP + H2O <=> Adenosine + Orthophosphate
P1,P4-Bis(5'-adenosyl)tetraphosphate + H2O <=> ATP + AMP
ATP + Adenosine <=> ADP + AMP
P1,P3-Bis(5'-adenosyl) triphosphate + H2O <=> ADP + AMP
Adenosine 3',5'-bisphosphate + H2O <=> AMP + Orthophosphate
ATP + Deamino-NAD+ + Ammonia <=> AMP + Diphosphate + NAD+
AMP + Diphosphate <=> Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate
3',5'-Cyclic AMP + H2O <=> AMP
S-Adenosyl-L-homocysteine + H2O <=> Adenosine + L-Homocysteine
S-Adenosyl-L-homocysteine + H2O <=> S-Inosyl-L-homocysteine + Ammonia
S-Adenosyl-L-homocysteine + H2O <=> S-Ribosyl-L-homocysteine + Adenine
2,3-Diaminopropanoate + H2O <=> Pyruvate + 2 Ammonia
(S)-Lactate + 2 Ferricytochrome c <=> Pyruvate + 2 Ferrocytochrome c + 2 H+
(R)-Lactate + 2 Ferricytochrome c <=> Pyruvate + 2 Ferrocytochrome c + 2 H+
(R)-Lactate + 2 Ferricytochrome c-553 <=> Pyruvate + 2 Ferrocytochrome c-553 + 2 H+
ATP + Pyruvate + H2O <=> AMP + Phosphoenolpyruvate + Orthophosphate
ATP + Pyruvate <=> ADP + Phosphoenolpyruvate
Methylglyoxal + NAD+ + H2O <=> Pyruvate + NADH + H+
Methylglyoxal + NADP+ + H2O <=> Pyruvate + NADPH + H+
ATP + Pyruvate + Orthophosphate <=> AMP + Phosphoenolpyruvate + Diphosphate
Pyruvate + Orthophosphate + Oxygen <=> Acetyl phosphate + Hydrogen peroxide + CO2
Phosphoenolpyruvate + H2O <=> Pyruvate + Orthophosphate
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
Pyruvate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H+
Pyruvate + CoA + Oxygen <=> Hydrogen peroxide + Acetyl-CoA + CO2
Acetyl-CoA + Formate <=> CoA + Pyruvate
O-Carbamoyl-L-serine + H2O <=> Pyruvate + 2 Ammonia + CO2
(S)-Malate + NAD+ <=> Pyruvate + CO2 + NADH + H+
(R)-Malate + NAD+ <=> Pyruvate + CO2 + NADH + H+
(S)-Malate + NADP+ <=> Pyruvate + CO2 + NADPH + H+
Oxaloacetate <=> Pyruvate + CO2
Acetylenedicarboxylate + H2O <=> Pyruvate + CO2
Pyruvate + CO2 <=> 2-Hydroxyethylenedicarboxylate
L-Serine <=> Pyruvate + Ammonia
D-Serine <=> Pyruvate + Ammonia
Serine <=> Pyruvate + Ammonia
Pyruvate <=> Acetaldehyde + CO2
(S)-2-Acetolactate + CO2 <=> 2 Pyruvate
Acetyl-CoA + H2O <=> CoA + Acetate
Acetaldehyde + CoA + NAD+ <=> Acetyl-CoA + NADH + H+
ATP + Acetate + CoA <=> ADP + Acetyl-CoA + Orthophosphate
Acetyl-CoA + Orthophosphate <=> CoA + Acetyl phosphate
Malonyl-CoA <=> Acetyl-CoA + CO2
ATP + Acetate + CoA <=> AMP + Diphosphate + Acetyl-CoA
Acetyl adenylate + CoA <=> AMP + Acetyl-CoA
(3S)-Citramalyl-CoA <=> Acetyl-CoA + Pyruvate
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
ATP + L-Glutamate <=> ADP + L-Glutamyl 5-phosphate
L-Glutamate + NAD+ + H2O <=> 2-Oxoglutarate + Ammonia + NADH + H+
L-Glutamate 5-semialdehyde + NAD+ + H2O <=> L-Glutamate + NADH + H+
L-Glutamate + NADP+ + H2O <=> 2-Oxoglutarate + Ammonia + NADPH + H+
L-Glutamate + Oxygen + H2O <=> 2-Oxoglutarate + Ammonia + Hydrogen peroxide
ATP + 5-Oxoproline + 2 H2O <=> ADP + Orthophosphate + L-Glutamate
ATP + L-Glutamate + Ammonia <=> ADP + Orthophosphate + L-Glutamine
L-Glutamate + Ammonia + CO2 <=> N-Carbamyl-L-glutamate + H2O
L-Glutamine + H2O <=> L-Glutamate + Ammonia
ATP + Deamino-NAD+ + L-Glutamine + H2O <=> AMP + Diphosphate + NAD+ + L-Glutamate
L-Alanine + 2-Oxoglutarate <=> Pyruvate + L-Glutamate
Acetyl-CoA + L-Glutamate <=> CoA + N-Acetyl-L-glutamate
L-Glutamate <=> D-Glutamate
L-Glutamate <=> 4-Aminobutanoate + CO2
L-threo-3-Methylaspartate <=> L-Glutamate
L-Glutamate <=> Poly-gamma-D-glutamate
2,5-Dioxopentanoate + NADP+ + H2O <=> 2-Oxoglutarate + NADPH + H+
2-Oxoglutarate + CoA + NADP+ <=> Succinyl-CoA + CO2 + NADPH + H+
Isocitrate + NADP+ <=> 2-Oxoglutarate + CO2 + NADPH + H+
Oxalosuccinate <=> 2-Oxoglutarate + CO2
2-Oxoglutaramate + H2O <=> 2-Oxoglutarate + Ammonia
2-Oxoglutarate + Ammonia <=> 4-Oxoglutaramate + H2O
Acetyl-CoA + H2O + 2-Oxoglutarate <=> (R)-2-Hydroxybutane-1,2,4-tricarboxylate + CoA
2-Oxoglutarate <=> Succinate semialdehyde + CO2
Oxalate + Oxygen <=> Hydrogen peroxide + 2 CO2
Hydrogen peroxide + 2 Glutathione <=> Glutathione disulfide + 2 H2O
2 Superoxide + 2 H+ <=> Hydrogen peroxide + Oxygen
Pyridoxamine phosphate + H2O + Oxygen <=> Pyridoxal phosphate + Ammonia + Hydrogen peroxide
Pyridoxine phosphate + Oxygen <=> Hydrogen peroxide + Pyridoxal phosphate
D-Glutamate + H2O + Oxygen <=> 2-Oxoglutarate + Ammonia + Hydrogen peroxide
Acceptor + 2 Nitric oxide + 2 H2O <=> Reduced acceptor + 2 Nitrite
Acceptor + NADPH + H+ <=> Reduced acceptor + NADP+
Acceptor + Ammonia + H2O + 2 Orthophosphate + 2 ADP <=> Hydroxylamine + Reduced acceptor + 2 ATP + 2 H2O
Acceptor + Ammonia + H2O <=> Hydroxylamine + Reduced acceptor
UDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + 2 H+
UDP-glucose + H2O <=> UMP + D-Glucose 1-phosphate
UTP + D-Glucose 1-phosphate <=> Diphosphate + UDP-glucose
UDP-glucose <=> UDP-alpha-D-galactose
UDP-glucose + Amylose <=> UDP + Amylose
UDP-glucose <=> UDP-4-dehydro-6-deoxy-D-glucose + H2O
2 Nitric oxide + 2 Ferrocytochrome c + 2 H+ <=> Nitrous oxide + 2 Ferricytochrome c + H2O
Trithionate + HO- + Acceptor + 2 H2O <=> Reduced acceptor + 3 HSO3-
(R)-Lactate + Acceptor <=> Pyruvate + Reduced acceptor
(S)-2-Hydroxyglutarate + Acceptor <=> 2-Oxoglutarate + Reduced acceptor
ATP + D-Glucose <=> ADP + D-Glucose 6-phosphate
D-Glucose + NAD+ <=> D-Glucono-1,5-lactone + NADH + H+
D-Glucose + NADP+ <=> D-Glucono-1,4-lactone + NADPH + H+
D-Glucose + Oxygen <=> 2-Dehydro-D-glucose + Hydrogen peroxide
D-Glucose 6-phosphate + H2O <=> D-Glucose + Orthophosphate
D-Glucose 1-phosphate + H2O <=> D-Glucose + Orthophosphate
D-Glucose + Quinone <=> D-Glucono-1,5-lactone + Hydroquinone
Cellobiose + H2O <=> 2 D-Glucose
D-Glucose <=> D-Fructose
1,3-beta-D-Glucan + H2O <=> D-Glucose + 1,3-beta-D-Glucan
Protoporphyrin + Fe2+ <=> Heme + 2 H+
Heme + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Biliverdin + CO + Fe2+ + 3 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Heme <=> Cytochrome a
Heme <=> Catalase
Heme <=> Peroxidase
ATP + Acetate <=> ADP + Acetyl phosphate
ATP + Acetate <=> Diphosphate + Acetyl adenylate
Acetyl phosphate + H2O <=> Acetate + Orthophosphate
Phosphonoacetate + H2O <=> Acetate + Orthophosphate
(S)-Lactate + Oxygen <=> Acetate + CO2 + H2O
Diphosphate + Acetate <=> Orthophosphate + Acetyl phosphate
Acetamide + H2O <=> Acetate + Ammonia
Acetyl adenylate + H2O <=> AMP + Acetate
Acetylpyruvate + H2O <=> Acetate + Pyruvate
(S)-2-Methylmalate <=> Acetate + Pyruvate
Acetaldehyde + Acceptor + H2O <=> Acetate + Reduced acceptor
6-Acetyl-D-glucose + H2O <=> D-Glucose + Acetate
GDP + H2O <=> GMP + Orthophosphate
NDP + H2O <=> Nucleotide + Orthophosphate
ATP + GDP <=> ADP + GTP
ATP + NDP <=> ADP + Nucleoside triphosphate
ATP + GMP <=> ADP + GDP
Nucleoside triphosphate + AMP <=> NDP + ADP
ATP + Nucleoside phosphate <=> ADP + NDP
GTP + H2O <=> GDP + Orthophosphate
Guanosine 3',5'-bis(diphosphate) + H2O <=> GDP + Diphosphate
GDP-glucose + H2O <=> GDP + D-Glucose
Oxaloacetate + H2O <=> Oxalate + Acetate
(R,R)-Tartaric acid <=> Oxaloacetate + H2O
(S,S)-Tartaric acid <=> Oxaloacetate + H2O
ATP + Oxaloacetate <=> ADP + Phosphoenolpyruvate + CO2
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+
(S)-Malate + NADP+ <=> Oxaloacetate + NADPH + H+
ATP + Pyruvate + HCO3- <=> ADP + Orthophosphate + Oxaloacetate
Orthophosphate + Oxaloacetate <=> H2O + Phosphoenolpyruvate + CO2
Diphosphate + Oxaloacetate <=> Orthophosphate + Phosphoenolpyruvate + CO2
erythro-3-Hydroxy-Ls-aspartate <=> Oxaloacetate + Ammonia
2-Oxosuccinamate + H2O <=> Oxaloacetate + Ammonia
4-Carboxy-4-hydroxy-2-oxoadipate <=> Oxaloacetate + Pyruvate
Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate
ATP + Citrate + CoA <=> ADP + Orthophosphate + Acetyl-CoA + Oxaloacetate
Malonyl-CoA + Pyruvate <=> Acetyl-CoA + Oxaloacetate
(3S)-Citryl-CoA <=> Acetyl-CoA + Oxaloacetate
L-Aspartate + 2-Oxoglutarate <=> Oxaloacetate + L-Glutamate
L-Aspartate + H2O + Oxygen <=> Oxaloacetate + Ammonia + Hydrogen peroxide
D-Aspartate + H2O + Oxygen <=> Oxaloacetate + Ammonia + Hydrogen peroxide
(S)-Malate + Oxygen <=> Oxaloacetate + Hydrogen peroxide
(S)-Malate + Quinone <=> Oxaloacetate + Hydroquinone
Citrate <=> Acetate + Oxaloacetate
Oxaloacetate <=> 2-Hydroxyethylenedicarboxylate
Glycine + H2O + 2 Ferricytochrome c <=> Glyoxylate + Ammonia + 2 Ferrocytochrome c + 2 H+
Glycine + H2O + NAD+ <=> Glyoxylate + Ammonia + NADH + H+
Glycine + H2O + Oxygen <=> Glyoxylate + Ammonia + Hydrogen peroxide
S-Adenosyl-L-methionine + Glycine <=> S-Adenosyl-L-homocysteine + Sarcosine
N-(Carboxymethyl)-D-alanine + NAD+ + H2O <=> Glycine + Pyruvate + NADH + H+
L-Alanine + Glyoxylate <=> Pyruvate + Glycine
Acetyl-CoA + Glycine <=> CoA + L-2-Amino-3-oxobutanoic acid
Glycine + 2-Oxoglutarate <=> Glyoxylate + L-Glutamate
Glycine + Oxaloacetate <=> Glyoxylate + L-Aspartate
Glycine + 2 Acceptor <=> Cyanide ion + CO2 + 2 Reduced acceptor + H+
dATP + DNA <=> Diphosphate + DNA
dGTP + DNA <=> Diphosphate + DNA
dCTP + DNA <=> Diphosphate + DNA
dTTP + DNA <=> Diphosphate + DNA
Deoxynucleoside triphosphate + DNA(n) <=> Diphosphate + DNA(n+1)
S-Adenosyl-L-methionine + DNA <=> S-Adenosyl-L-homocysteine + DNA 5-methylcytosine
ATP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Diphosphate + DNA(n+m)
NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m)
Acyl-CoA + H2O <=> CoA + Carboxylate
Acyl-CoA + NAD+ <=> trans-2,3-Dehydroacyl-CoA + NADH + H+
Acyl-CoA + NADP+ <=> 2,3-Dehydroacyl-CoA + NADPH + H+
Acyl-CoA + NADP+ <=> cis-2,3-Dehydroacyl-CoA + NADPH + H+
Acyl-CoA + Oxygen <=> trans-2,3-Dehydroacyl-CoA + Hydrogen peroxide
ATP + Medium-chain fatty acid + CoA <=> AMP + Diphosphate + Medium-chain acyl-CoA
ATP + Long-chain fatty acid + CoA <=> AMP + Diphosphate + Long-chain acyl-CoA
Acyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoacyl-CoA
Acyl-CoA + Electron-transferring flavoprotein <=> 2,3-Dehydroacyl-CoA + Reduced electron-transferring flavoprotein
Acyl-CoA + Acetate <=> Fatty acid anion + Acetyl-CoA
GTP + Carboxylate + CoA <=> GDP + Orthophosphate + Acyl-CoA
Acyl-CoA + Glycine <=> CoA + N-Acylglycine
L-Alanine + NAD+ + H2O <=> Pyruvate + Ammonia + NADH + H+
L-Aspartate <=> L-Alanine + CO2
Alanopine + NAD+ + H2O <=> L-Alanine + Pyruvate + NADH + H+
D-Alanine + Acetyl-CoA <=> 2-Amino-4-oxopentanoic acid + CoA
L-Alanine + Oxaloacetate <=> Pyruvate + L-Aspartate
L-Alanine <=> D-Alanine
Succinate + NAD+ <=> Fumarate + NADH + H+
ATP + Succinate + CoA <=> ADP + Orthophosphate + Succinyl-CoA
Succinyl-CoA + (S)-Malate <=> Succinate + L-Malyl-CoA
Succinyl-CoA + H2O <=> CoA + Succinate
Succinate + FAD <=> FADH2 + Fumarate
(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate <=> Pyruvate + Succinate
Succinyl-CoA + Acetoacetate <=> Succinate + Acetoacetyl-CoA
N-Succinyl-L-glutamate + H2O <=> L-Glutamate + Succinate
Succinate + Acceptor <=> Fumarate + Reduced acceptor
UDP-N-acetyl-alpha-D-glucosamine + H2O <=> N-Acetyl-D-mannosamine + UDP
UTP + N-Acetyl-alpha-D-glucosamine 1-phosphate <=> Diphosphate + UDP-N-acetyl-alpha-D-glucosamine
UDP-N-acetyl-alpha-D-glucosamine + Protein asparagine <=> UDP + 4-N-(N-Acetyl-D-glucosaminyl)-protein
UDP-N-acetyl-alpha-D-glucosamine <=> UDP-N-acetyl-D-galactosamine
UDP-N-acetyl-alpha-D-glucosamine <=> UDP-N-acetyl-D-mannosamine
UDP-N-acetyl-alpha-D-glucosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + 2 NADH + 2 H+
UDP-N-acetyl-alpha-D-glucosamine <=> Glycolipid
UDP-N-acetyl-alpha-D-glucosamine <=> Mucopolysaccharide
GTP + H2O <=> 7,8-Dihydroneopterin 3'-triphosphate + Formate
GTP + 3 H2O <=> Formate + 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + Diphosphate
GTP + H2O <=> GMP + Diphosphate
GTP + H2O <=> Formamidopyrimidine nucleoside triphosphate
ATP + GTP <=> AMP + Guanosine 3'-diphosphate 5'-triphosphate
GTP + Pyruvate <=> GDP + Phosphoenolpyruvate
GTP + Oxaloacetate <=> GDP + Phosphoenolpyruvate + CO2
GTP + Succinate + CoA <=> GDP + Orthophosphate + Succinyl-CoA
GTP <=> 3',5'-Cyclic GMP + Diphosphate
ATP + RNA <=> Diphosphate + RNA
ATP + RNA <=> AMP + Diphosphate + RNA(circular)
RNA + Orthophosphate <=> RNA + ADP
RNA + Orthophosphate <=> RNA + UDP
RNA + Orthophosphate <=> RNA + GDP
RNA + Orthophosphate <=> RNA + CDP
GTP + RNA <=> Diphosphate + RNA
CTP + RNA <=> Diphosphate + RNA
UTP + RNA <=> Diphosphate + RNA
Nucleoside triphosphate + RNA <=> Diphosphate + RNA
L-Lysine + NAD+ <=> Delta1-Piperideine-2-carboxylate + Ammonia + NADH + H+
L-Lysine + NAD+ + H2O <=> L-2-Aminoadipate 6-semialdehyde + NADH + Ammonia + H+
L-Lysine + Oxygen + H2O <=> 6-Amino-2-oxohexanoate + Ammonia + Hydrogen peroxide
L-Lysine + Oxygen + NADPH + H+ <=> N6-Hydroxy-L-lysine + NADP+ + H2O
L-Lysine + Oxygen <=> 5-Aminopentanamide + CO2 + H2O
meso-2,6-Diaminoheptanedioate <=> L-Lysine + CO2
D-Lysopine + NADP+ + H2O <=> L-Lysine + Pyruvate + NADPH + H+
L-Lysine + Pyruvate <=> L-2-Aminoadipate 6-semialdehyde + L-Alanine
L-Lysine + Acetyl-CoA <=> N6-Acetyl-L-lysine + CoA
L-Lysine + 2-Oxoglutarate <=> L-2-Aminoadipate 6-semialdehyde + L-Glutamate
N6-Acetyl-L-lysine + H2O <=> Acetate + L-Lysine
L-Lysine <=> L-Pipecolate
L-Lysine <=> D-Lysine
L-Lysine <=> (3S)-3,6-Diaminohexanoate
L-Lysine <=> Cadaverine + CO2
L-Lysine 1,6-lactam + H2O <=> L-Lysine
Glycolate + NADP+ <=> Glyoxylate + NADPH + H+
Glyoxylate + Oxygen + H2O <=> Oxalate + Hydrogen peroxide
Glyoxylate + CoA + NADP+ <=> Oxalyl-CoA + NADPH + H+
(S)-Ureidoglycolate + H2O <=> Glyoxylate + 2 Ammonia + CO2
4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate
(4R)-4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate
(S)-Malate + CoA <=> Acetyl-CoA + H2O + Glyoxylate
L-Malyl-CoA <=> Acetyl-CoA + Glyoxylate
2-Hydroxy-3-oxoadipate + CO2 <=> 2-Oxoglutarate + Glyoxylate
Glycolate + Oxygen <=> Glyoxylate + Hydrogen peroxide
Glycolate + Acceptor <=> Glyoxylate + Reduced acceptor
3-Oxalomalate <=> Oxaloacetate + Glyoxylate
erythro-3-Hydroxy-Ls-aspartate <=> Glycine + Glyoxylate
Isocitrate <=> Succinate + Glyoxylate
ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate
L-Aspartate + Oxygen <=> Iminoaspartate + Hydrogen peroxide
ATP + L-Aspartate + Ammonia <=> ADP + Orthophosphate + L-Asparagine
ATP + L-Aspartate + Ammonia <=> AMP + Diphosphate + L-Asparagine
N-Carbamoyl-L-aspartate + H2O <=> L-Aspartate + CO2 + Ammonia
L-Asparagine + H2O <=> L-Aspartate + Ammonia
3-Cyano-L-alanine + 2 H2O <=> L-Aspartate + Ammonia
Acetyl-CoA + L-Aspartate <=> CoA + N-Acetyl-L-aspartate
N-Acetyl-L-aspartate + H2O <=> Acetate + L-Aspartate
L-Aspartate <=> beta-Alanine + CO2
L-Aspartate <=> Fumarate + Ammonia
L-Aspartate <=> D-Aspartate
L-Aspartate + 2-Oxo acid <=> alpha-Amino acid + Oxaloacetate
Glutathione + H2O <=> Cys-Gly + L-Glutamate
ATP + gamma-L-Glutamyl-L-cysteine + Glycine <=> ADP + Orthophosphate + Glutathione
S-Succinylglutathione + H2O <=> Glutathione + Succinate
UDP-alpha-D-galactose + 2 NAD+ + H2O <=> UDP-D-galacturonate + 2 NADH + 2 H+
UTP + alpha-D-Galactose 1-phosphate <=> Diphosphate + UDP-alpha-D-galactose
UDP-alpha-D-galactose + D-Glucose <=> UDP + Lactose
UDP-alpha-D-galactose + UDP-N-acetyl-alpha-D-glucosamine <=> UMP + UDP-N-acetyl-6-(alpha-D-galactose-1-phospho)-alpha-D-glucosamine
UDP-alpha-D-galactose <=> UDP-alpha-D-galactofuranose
UDP-alpha-D-galactose + Galactan <=> Galactan + UDP
3'-Phosphoadenylyl sulfate + H2O <=> Sulfate + Adenosine 3',5'-bisphosphate
3'-Phosphoadenylyl sulfate + H2O <=> Adenylyl sulfate + Orthophosphate
ATP + Adenylyl sulfate <=> ADP + 3'-Phosphoadenylyl sulfate
CMP + H2O <=> Cytosine + D-Ribose 5-phosphate
CMP + H2O <=> Cytidine + Orthophosphate
ATP + CMP <=> ADP + CDP
ATP + Cytidine <=> ADP + CMP
CDP + H2O <=> CMP + Orthophosphate
CTP + H2O <=> CMP + Diphosphate
UTP + Cytidine <=> UDP + CMP
GTP + Cytidine <=> GDP + CMP
ATP + Formate <=> ADP + Formyl phosphate
Formate + NAD+ <=> H+ + CO2 + NADH
Formyl-CoA + H2O <=> CoA + Formate
Oxalate <=> Formate + CO2
Formamide + H2O <=> Formate + Ammonia
N-Formyl-L-glutamate + H2O <=> Formate + L-Glutamate
N-Formyl-L-aspartate + H2O <=> Formate + L-Aspartate
S-Formylglutathione + H2O <=> Formate + Glutathione
Sulfite + H2O + 2 Ferricytochrome c <=> Sulfate + 2 Ferrocytochrome c + 2 H+
ATP + Sulfate <=> Diphosphate + Adenylyl sulfate
ADP + Sulfate <=> Orthophosphate + Adenylyl sulfate
Adenylyl sulfate + H2O <=> AMP + Sulfate
L-Serine O-sulfate + H2O <=> Pyruvate + Ammonia + Sulfate
Sulfite + Oxygen + H2O <=> Sulfate + Hydrogen peroxide
D-Glucose 6-sulfate + H2O <=> D-Glucose + Sulfate
3'-Phosphoadenylyl sulfate + Estradiol-17beta <=> Adenosine 3',5'-bisphosphate + Estradiol-17beta 3-sulfate
3'-Phosphoadenylyl sulfate + 2-Methoxyestrone <=> Adenosine 3',5'-bisphosphate + 2-Methoxyestrone 3-sulfate
3'-Phosphoadenylyl sulfate + 2-Methoxy-17beta-estradiol <=> Adenosine 3',5'-bisphosphate + 2-Methoxyestradiol-17beta 3-sulfate
Aldehyde + NAD+ + H2O <=> Carboxylate + NADH + H+
Acyl phosphate + H2O <=> Carboxylate + Orthophosphate
Nitrile + 2 H2O <=> Carboxylate + Ammonia
5'-Acylphosphoadenosine + H2O <=> AMP + Carboxylate
3-Acylpyruvate + H2O <=> Carboxylate + Pyruvate
Aldehyde + Acceptor + H2O <=> Carboxylate + Reduced acceptor
N6-Acyl-L-lysine + H2O <=> Carboxylate + L-Lysine
N-Acyl-L-aspartate + H2O <=> Carboxylate + L-Aspartate
S-Acylglutathione + H2O <=> Carboxylate + Glutathione
FMN + H2O <=> Riboflavin + Orthophosphate
ATP + Riboflavin <=> ADP + FMN
D-Glucose 1-phosphate + Riboflavin <=> D-Glucose + FMN
L-Arginine + H2O <=> L-Ornithine + Urea
L-Arginine + H2O <=> L-Citrulline + Ammonia
ATP + L-Arginine <=> ADP + L-Arginine phosphate
NAD+ + Protein-L-arginine <=> Nicotinamide + Protein-omega-N-(ADP-D-ribosyl)-L-arginine
2 L-Arginine + 4 Oxygen + 3 NADPH + 3 H+ <=> 2 Nitric oxide + 2 L-Citrulline + 3 NADP+ + 4 H2O
L-Arginine + Oxygen + NADPH + H+ <=> N(omega)-Hydroxyarginine + NADP+ + H2O
L-Arginine + Oxygen <=> 4-Guanidinobutanamide + CO2 + H2O
Octopine + NAD+ + H2O <=> L-Arginine + Pyruvate + NADH + H+
Nopaline + NADP+ + H2O <=> L-Arginine + 2-Oxoglutarate + NADPH + H+
L-Arginine + Glycine <=> L-Ornithine + Guanidinoacetate
L-Arginine <=> Agmatine + CO2
L-Arginine <=> D-Arginine
CTP + H2O <=> UTP + Ammonia
CTP + H2O <=> CDP + Orthophosphate
ATP + CDP <=> ADP + CTP
ATP + UTP + Ammonia <=> ADP + Orthophosphate + CTP
CTP + Pyruvate <=> CDP + Phosphoenolpyruvate
ATP + UTP + L-Glutamine + H2O <=> ADP + Orthophosphate + CTP + L-Glutamate
CTP <=> 3',5'-Cyclic CMP + Diphosphate
2 ATP + L-Glutamine + HCO3- + H2O <=> 2 ADP + Orthophosphate + L-Glutamate + Carbamoyl phosphate
L-Glutamine + Pyruvate <=> 2-Oxoglutaramate + L-Alanine
Acyl-CoA + L-Glutamine <=> CoA + N-Acyl-L-glutamine
ATP + L-Aspartate + L-Glutamine + H2O <=> AMP + Diphosphate + L-Asparagine + L-Glutamate
L-Glutamine <=> D-Glutamine
L-Serine + NAD+ + H2O <=> Hydroxypyruvate + Ammonia + NADH + H+
O-Phospho-L-serine + H2O <=> L-Serine + Orthophosphate
Diphosphate + L-Serine <=> Orthophosphate + O-Phospho-L-serine
L-Serine + Pyruvate <=> Hydroxypyruvate + L-Alanine
L-Serine + Acetyl-CoA <=> O-Acetyl-L-serine + CoA
L-Serine + Glyoxylate <=> Hydroxypyruvate + Glycine
L-Serine <=> D-Serine
L-Serine <=> Dehydroalanine + H2O
S-Adenosyl-L-methionine + tRNA containing uridine at position 54 <=> S-Adenosyl-L-homocysteine + tRNA containing ribothymidine at position 54
S-Adenosyl-L-methionine + tRNA cytosine <=> S-Adenosyl-L-homocysteine + tRNA containing 5-methylcytosine
S-Adenosyl-L-methionine + tRNA adenine <=> S-Adenosyl-L-homocysteine + tRNA containing N1-methyladenine
S-Adenosyl-L-methionine + tRNA guanine <=> S-Adenosyl-L-homocysteine + tRNA containing N1-methylguanine
S-Adenosyl-L-methionine + tRNA guanine <=> S-Adenosyl-L-homocysteine + tRNA containing N2-methylguanine
S-Adenosyl-L-methionine + tRNA adenine <=> S-Adenosyl-L-homocysteine + tRNA containing N6-methyladenine
S-Adenosyl-L-methionine + tRNA guanine <=> S-Adenosyl-L-homocysteine + tRNA containing N7-methylguanine
S-Adenosyl-L-methionine + tRNA containing 5-(aminomethyl)-2-thiouridine <=> S-Adenosyl-L-homocysteine + tRNA containing 5-[(methylamino)methyl]-2-thiouridylate
Methanol + Hydrogen peroxide <=> Formaldehyde + 2 H2O
Dichloromethane + H2O <=> Formaldehyde + 2 Hydrochloric acid
Formaldehyde + NAD+ + H2O <=> Formate + NADH + H+
Methanol + NAD+ <=> Formaldehyde + NADH + H+
Methylamine + H2O + 2 Amicyanin <=> Formaldehyde + Ammonia + 2 Reduced amicyanin + 2 H+
Methanol + Oxygen <=> Formaldehyde + Hydrogen peroxide
N-Methyl-L-glutamate + Acceptor + H2O <=> L-Glutamate + Formaldehyde + Reduced acceptor
Sarcosine + H2O + Oxygen <=> Glycine + Formaldehyde + Hydrogen peroxide
Sarcosine + Electron-transferring flavoprotein + H2O <=> Glycine + Formaldehyde + Reduced electron-transferring flavoprotein
N6-Methyl-L-lysine + H2O + Oxygen <=> L-Lysine + Formaldehyde + Hydrogen peroxide
2 Formaldehyde + H2O <=> Formate + Methanol
Thiamin diphosphate + H2O <=> Thiamin monophosphate + Orthophosphate
ATP + Thiamin diphosphate <=> ADP + Thiamin triphosphate
ATP + Thiamin monophosphate <=> ADP + Thiamin diphosphate
Thiamin triphosphate + H2O <=> Thiamin diphosphate + Orthophosphate
ATP + Thiamine <=> AMP + Thiamin diphosphate
2-Oxoglutarate + Thiamin diphosphate <=> 3-Carboxy-1-hydroxypropyl-ThPP + CO2
Primary alcohol + NAD+ <=> Aldehyde + NADH + H+
Secondary alcohol + NAD+ <=> Ketone + NADH + H+
Primary alcohol + NADP+ <=> Aldehyde + NADPH + H+
Orthophosphoric monoester + H2O <=> Alcohol + Orthophosphate
Acetyl-CoA + Alcohol <=> CoA + Acetic ester
Acetic ester + H2O <=> Alcohol + Acetate
Alcohol + 3'-Phosphoadenylyl sulfate <=> Alkyl sulfate + Adenosine 3',5'-bisphosphate
Ester + H2O <=> Alcohol + Carboxylate
Aldehyde + NAD+ + H2O <=> Fatty acid + NADH + H+
Aldehyde + NADP+ + H2O <=> Carboxylate + NADPH + H+
Aldehyde + Oxygen + H2O <=> Carboxylate + Hydrogen peroxide
2-Oxo acid <=> Aldehyde + CO2
Primary alcohol + Oxygen <=> Aldehyde + Hydrogen peroxide
Aldehyde + Acceptor + H2O <=> Fatty acid + Reduced acceptor
Primary alcohol + Acceptor <=> Aldehyde + Reduced acceptor
L-Galactono-1,4-lactone + 2 Ferricytochrome c <=> Ascorbate + 2 Ferrocytochrome c + 2 H+
L-Galactono-1,4-lactone + Oxygen <=> Ascorbate + Hydrogen peroxide
Ascorbate + Hydrogen peroxide <=> Dehydroascorbate + 2 H2O
2 Ascorbate + Acceptor <=> 2 Monodehydroascorbate + Reduced acceptor
Ascorbate + Oxygen + H2O <=> Threonate + Oxalate
Ascorbate <=> L-xylo-Hexulonolactone
L-Methionine + H2O + Oxygen <=> 4-Methylthio-2-oxobutanoic acid + Ammonia + Hydrogen peroxide
S-Adenosyl-L-methionine + L-Methionine <=> S-Adenosyl-L-homocysteine + S-Methyl-L-methionine
S-Adenosyl-L-methionine + L-Homocysteine <=> S-Adenosyl-L-homocysteine + L-Methionine
O-Acetyl-L-homoserine + Methanethiol <=> L-Methionine + Acetate
L-Methionine + Glyoxylate <=> 4-Methylthio-2-oxobutanoic acid + Glycine
N-Formylmethionine + H2O <=> Formate + L-Methionine
L-Methionine + H2O <=> Methanethiol + Ammonia + 2-Oxobutanoate
L-Methionine <=> D-Methionine
L-Methionine <=> 3-Methylthiopropanamine + CO2
Aminoacyl-L-methionine + H2O <=> L-Methionine
2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O
UTP + Pyruvate <=> UDP + Phosphoenolpyruvate
Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + Orthophosphate
Phosphoenolpyruvate <=> 3-Phosphonopyruvate
UTP + H2O <=> UMP + Diphosphate
2 Benzoyl-CoA + L-Ornithine <=> 2 CoA + N2,N5-Dibenzoyl-L-ornithine
L-Citrulline + H2O <=> L-Ornithine + CO2 + Ammonia
N5-(L-1-Carboxyethyl)-L-ornithine + NADP+ + H2O <=> L-Ornithine + Pyruvate + NADPH + H+
L-Ornithine + 2-Oxoglutarate <=> L-Glutamate 5-semialdehyde + L-Glutamate
L-Ornithine + 2-Oxoglutarate <=> Delta1-Pyrroline-5-carboxylate + L-Glutamate + H2O
N-Acetylornithine + H2O <=> Acetate + L-Ornithine
L-Ornithine <=> Putrescine + CO2
L-Ornithine <=> L-Proline + Ammonia
L-Ornithine <=> D-Ornithine
L-Tryptophan + H2O <=> Indole + Pyruvate + Ammonia
L-Serine + Indole <=> L-Tryptophan + H2O
L-Tryptophan + NAD+ + H2O <=> Indolepyruvate + Ammonia + NADH + H+
L-Tryptophan + NADP+ + H2O <=> Indolepyruvate + Ammonia + NADPH + H+
L-Tryptophan + H2O + Oxygen <=> Indolepyruvate + Ammonia + Hydrogen peroxide
L-Tryptophan + Oxygen <=> L-Formylkynurenine
L-Tryptophan + Oxygen <=> (Indol-3-yl)acetamide + CO2 + H2O
L-Tryptophan + Oxygen <=> (Indol-3-yl)glycolaldehyde + Ammonia + CO2
L-Tryptophanamide + H2O <=> L-Tryptophan + Ammonia
S-Adenosyl-L-methionine + L-Tryptophan <=> S-Adenosyl-L-homocysteine + Abrine
L-Tryptophan + 2-Oxoglutarate <=> Indolepyruvate + L-Glutamate
L-Tryptophan <=> Tryptamine + CO2
ATP + L-Phenylalanine + H2O <=> AMP + Diphosphate + D-Phenylalanine
L-Phenylalanine + H2O + NAD+ <=> Phenylpyruvate + Ammonia + NADH + H+
L-Phenylalanine + H2O + Oxygen <=> Phenylpyruvate + Ammonia + Hydrogen peroxide
L-Phenylalanine + Oxygen <=> 2-Phenylacetamide + CO2 + H2O
L-Arogenate <=> L-Phenylalanine + H2O + CO2
L-Phenylalanine + Pyruvate <=> Phenylpyruvate + L-Alanine
Acetyl-CoA + L-Phenylalanine <=> CoA + N-Acetyl-L-phenylalanine
L-Phenylalanine + 2-Oxoglutarate <=> Phenylpyruvate + L-Glutamate
L-Aspartate + Phenylpyruvate <=> Oxaloacetate + L-Phenylalanine
L-Phenylalanine <=> trans-Cinnamate + Ammonia
L-Phenylalanine + Oxygen <=> 2-Phenylacetamide + CO2
L-Phenylalanine <=> Phenethylamine + CO2
Hydrogen + NAD+ <=> NADH + H+
2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+
(R)-Lactate + NAD+ <=> Pyruvate + NADH + H+
3-Oxopropanoate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
3-Oxopropanoate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H+
(S)-1-Pyrroline-5-carboxylate + NAD+ + 2 H2O <=> L-Glutamate + NADH + H+
(S)-1-Pyrroline-5-carboxylate + NADP+ + 2 H2O <=> L-Glutamate + NADPH + H+
Isocitrate + NAD+ <=> 2-Oxoglutarate + CO2 + NADH + H+
Acetaldehyde + NAD+ + H2O <=> Acetate + NADH + H+
Acetaldehyde + NADP+ + H2O <=> Acetate + NADPH + H+
Succinate semialdehyde + NAD+ + H2O <=> Succinate + NADH + H+
Succinate semialdehyde + NADP+ + H2O <=> Succinate + NADPH + H+
N6-(L-1,3-Dicarboxypropyl)-L-lysine + NAD+ + H2O <=> L-Lysine + 2-Oxoglutarate + NADH + H+
N6-(L-1,3-Dicarboxypropyl)-L-lysine + NADP+ + H2O <=> L-Lysine + 2-Oxoglutarate + NADPH + H+
Glycolate + NAD+ <=> Glyoxylate + NADH + H+
ITP + H2O <=> IDP + Orthophosphate
ITP + H2O <=> IMP + Diphosphate
ATP + IDP <=> ADP + ITP
Inosine 5'-tetraphosphate + H2O <=> ITP + Orthophosphate
ITP + Pyruvate <=> IDP + Phosphoenolpyruvate
ITP + D-Glucose <=> IDP + D-Glucose 6-phosphate
ITP + Oxaloacetate <=> IDP + Phosphoenolpyruvate + CO2
ITP + Succinate + CoA <=> IDP + Orthophosphate + Succinyl-CoA
L-Tyrosine + H2O <=> Phenol + Pyruvate + Ammonia
L-Tyrosine + H2O + Oxygen <=> 3-(4-Hydroxyphenyl)pyruvate + Ammonia + Hydrogen peroxide
L-Tyrosine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-tyrosine + [Oxidized NADPH---hemoprotein reductase] + H2O
L-Tyrosine + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + H2O
L-Arogenate + NAD+ <=> L-Tyrosine + CO2 + NADH + H+
L-Arogenate + NADP+ <=> L-Tyrosine + CO2 + NADPH + H+
L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
ATP + L-Tyrosine + L-Arginine <=> AMP + Diphosphate + Kyotorphin
L-Tyrosine <=> Tyramine + CO2
L-Tyrosine <=> 4-Coumarate + Ammonia
L-Tyrosine <=> 3-Amino-3-(4-hydroxyphenyl)propanoate
3-Oxopropanoate + CoA + NADP+ <=> Malonyl-CoA + NADPH + H+
ATP + Acetyl-CoA + HCO3- <=> ADP + Orthophosphate + Malonyl-CoA
Acetyl-CoA + Malonate <=> Acetate + Malonyl-CoA
Malonyl-CoA + NADPH + H+ <=> 3-Oxopropionyl-CoA + NADP+ + H2O
Ethanol + NADP+ <=> Acetaldehyde + NADPH + H+
Phosphonoacetaldehyde + H2O <=> Acetaldehyde + Orthophosphate
Ethanolamine phosphate + H2O <=> Acetaldehyde + Ammonia + Orthophosphate
Ethanolamine <=> Acetaldehyde + Ammonia
Acetaldehyde + Pyruvate <=> 4-Hydroxy-2-oxopentanoate
L-Threonine <=> Glycine + Acetaldehyde
(S)-Lactate <=> Formate + Acetaldehyde
Ethanol + NAD+ <=> Acetaldehyde + NADH + H+
Acetaldehyde + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate
ATP + D-Fructose 6-phosphate <=> ADP + D-Fructose 1,6-bisphosphate
D-Mannitol 1-phosphate + NAD+ <=> D-Fructose 6-phosphate + NADH + H+
ATP + D-Fructose <=> ADP + D-Fructose 6-phosphate
D-Fructose 6-phosphate + Orthophosphate <=> Acetyl phosphate + D-Erythrose 4-phosphate + H2O
D-Fructose 1,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate
beta-D-Fructose 2,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate
Diphosphate + D-Fructose 6-phosphate <=> Orthophosphate + D-Fructose 1,6-bisphosphate
D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia
UDP-glucose + D-Fructose 6-phosphate <=> UDP + Sucrose 6'-phosphate
CTP + D-Fructose 6-phosphate <=> CDP + D-Fructose 1,6-bisphosphate
L-Glutamine + D-Fructose 6-phosphate <=> L-Glutamate + D-Glucosamine 6-phosphate
UTP + D-Fructose 6-phosphate <=> UDP + D-Fructose 1,6-bisphosphate
ITP + D-Fructose 6-phosphate <=> IDP + D-Fructose 1,6-bisphosphate
D-Glucose 6-phosphate <=> D-Fructose 6-phosphate
D-Mannose 6-phosphate <=> D-Fructose 6-phosphate
ATP + Urea + HCO3- <=> ADP + Orthophosphate + Urea-1-carboxylate
Guanidinoacetate + H2O <=> Glycine + Urea
(S)-Ureidoglycolate <=> Glyoxylate + Urea
N-Amidino-L-aspartate + H2O <=> L-Aspartate + Urea
Urea <=> Cyanamide + H2O
L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia
Nitric oxide + H2O + Ferricytochrome c <=> Nitrite + Ferrocytochrome c + H+
Nitric oxide + H2O + Ferricytochrome c2 <=> Nitrite + Ferrocytochrome c2 + H+
Nitric oxide + H2O + Oxidized azurin <=> Nitrite + Reduced azurin + H+
Ammonia + 3 NAD+ + 2 H2O <=> Nitrite + 3 NADH + 3 H+
Ammonia + 3 NADP+ + 2 H2O <=> Nitrite + 3 NADPH + 3 H+
Ammonia + 2 H2O + 6 Oxidized ferredoxin <=> Nitrite + 6 Reduced ferredoxin + 6 H+
Nitrite + H2O + 2 Oxidized ferredoxin <=> Nitrate + 2 Reduced ferredoxin
Nitrate + 2 Ferrocytochrome b <=> Nitrite + H2O + 2 Ferricytochrome b
Nitrite + H2O <=> Hydroxylamine + Oxygen
Nitrite + NAD+ + H2O <=> Nitrate + NADH + H+
Nitrite + NADP+ + H2O <=> Nitrate + NADPH + H+
Nitrite + Acceptor + H2O <=> Nitrate + Reduced acceptor
Nitrite + Acetaldehyde + Hydrogen peroxide <=> Nitroethane + Oxygen + H2O
2 Nitrite + Oxygen <=> 2 Nitrate
Sucrose + H2O <=> D-Fructose + D-Glucose
Sucrose + H2O <=> beta-D-Fructose + alpha-D-Glucose
Sucrose + Orthophosphate <=> D-Fructose + D-Glucose 1-phosphate
Sugar phosphate + H2O <=> Sugar + Orthophosphate
Sucrose 6'-phosphate + H2O <=> Sucrose + Orthophosphate
UDP-glucose + D-Fructose <=> UDP + Sucrose
Sucrose + FAD <=> 3-Ketosucrose + FADH2
Sucrose + Acceptor <=> 3-Ketosucrose + Reduced acceptor
UDP-alpha-D-galactose + Sucrose <=> UDP + 6F-alpha-D-Galactosylsucrose
Sucrose <=> Palatinose
Sucrose + Protein N(pi)-phospho-L-histidine <=> Sucrose 6-phosphate + Protein histidine
cis-1,2-Dihydrobenzene-1,2-diol + NAD+ <=> Catechol + NADH + H+
(1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ <=> Catechol + NADH + CO2 + H+
trans-1,2-Dihydrobenzene-1,2-diol + NADP+ <=> Catechol + NADPH + H+
Phenol + Oxygen + NADPH + H+ <=> Catechol + NADP+ + H2O
Catechol + Oxygen <=> 2-Hydroxymuconate semialdehyde
Catechol + Oxygen <=> cis,cis-Muconate
Salicylate + Oxygen + NADH + H+ <=> Catechol + CO2 + NAD+ + H2O
2,3-Dihydroxybenzoate <=> Catechol + CO2
3,4-Dihydroxybenzoate <=> Catechol + CO2
Anthranilate + Oxygen + NADH + H+ <=> Catechol + Ammonia + CO2 + NAD+
Anthranilate + Oxygen + NADPH + H+ <=> Catechol + Ammonia + CO2 + NADP+
S-Adenosyl-L-methionine + Catechol <=> S-Adenosyl-L-homocysteine + o-Methoxyphenol
2-Nitrophenol + Oxygen + 2 NADPH + 2 H+ <=> Catechol + Nitrite + 2 NADP+ + H2O
Succinyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoadipyl-CoA
Succinyl-CoA + Glycine <=> 5-Aminolevulinate + CoA + CO2
Succinyl-CoA + L-Arginine <=> CoA + N2-Succinyl-L-arginine
(R)-Methylmalonyl-CoA <=> Succinyl-CoA
Sorbitol 6-phosphate + NADP+ <=> D-Glucose 6-phosphate + NADPH + H+
D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+
UDP-glucose + D-Glucose 6-phosphate <=> UDP + alpha,alpha'-Trehalose 6-phosphate
H2O + alpha,alpha'-Trehalose 6-phosphate <=> D-Glucose + D-Glucose 6-phosphate
H2O + Maltose 6'-phosphate <=> D-Glucose + D-Glucose 6-phosphate
6-Phospho-beta-D-glucosyl-(1,4)-D-glucose + H2O <=> D-Glucose + D-Glucose 6-phosphate
sn-Glycerol 3-phosphate + H2O <=> Glycerol + Orthophosphate
sn-Glycerol 3-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+
sn-Glycerol 3-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+
sn-Glycerol 3-phosphate + NADP+ <=> D-Glyceraldehyde 3-phosphate + NADPH + H+
sn-Glycerol 3-phosphate + Oxygen <=> Glycerone phosphate + Hydrogen peroxide
ATP + Glycerol <=> ADP + sn-Glycerol 3-phosphate
sn-Glycerol 3-phosphate + FAD <=> Glycerone phosphate + FADH2
sn-Glycerol 3-phosphate + Quinone <=> Glycerone phosphate + Hydroquinone
sn-Glycerol 3-phosphate + D-Glucose <=> Glycerol + D-Glucose 6-phosphate
sn-Glycerol 3-phosphate + Acyl-CoA <=> 1-Acyl-sn-glycerol 3-phosphate + CoA
UDP-alpha-D-galactose + sn-Glycerol 3-phosphate <=> UDP + 2-(alpha-D-Galactosyl)-sn-glycerol 3-phosphate
UDP-alpha-D-galactose + sn-Glycerol 3-phosphate <=> UDP + alpha-D-Galactosyl-(1,1')-sn-glycerol 3-phosphate
CDP-glycerol + H2O <=> CMP + sn-Glycerol 3-phosphate
CTP + sn-Glycerol 3-phosphate <=> Diphosphate + CDP-glycerol
Glycerophosphodiester + H2O <=> Alcohol + sn-Glycerol 3-phosphate
Hydrogen sulfide + 3 NADP+ + 3 H2O <=> Sulfite + 3 NADPH + 3 H+
Hydrogen sulfide + 6 Oxidized ferredoxin + 3 H2O <=> Sulfite + 6 Reduced ferredoxin + 6 H+
Sulfite + Acceptor + AMP <=> Adenylyl sulfate + Reduced acceptor
Hydrogen sulfide + Protein disulfide + 2 Acceptor + 3 H2O <=> Sulfite + Protein dithiol + 2 Reduced acceptor + 2 H+
3-Sulfino-L-alanine <=> L-Alanine + Sulfur dioxide
Sulfite + Sulfur <=> Thiosulfate
Mannitol + 2 Ferricytochrome c <=> D-Fructose + 2 Ferrocytochrome c + 2 H+
ATP + D-Fructose <=> ADP + D-Fructose 1-phosphate
ATP + D-Fructose <=> ADP + beta-D-Fructose 6-phosphate
Mannitol + NAD+ <=> D-Fructose + NADH + H+
Mannitol + NADP+ <=> D-Fructose + NADPH + H+
D-Fructose + NADP+ <=> 5-Dehydro-D-fructose + NADPH + H+
beta-D-Fructose 2-phosphate + H2O <=> D-Fructose + Orthophosphate
D-Fructose + Ubiquinone <=> 5-Dehydro-D-fructose + Ubiquinol
D-Fructose + D-Glucose <=> D-Glucono-1,5-lactone + D-Sorbitol
D-Sorbitol + NAD+ <=> D-Fructose + NADH + H+
ITP + D-Fructose <=> IDP + D-Fructose 6-phosphate
D-Mannose <=> D-Fructose
alpha-D-Glucose <=> D-Fructose
Fructan(n+1) + H2O <=> D-Fructose + Fructan(n)
GDP-mannose + H2O + 2 NAD+ <=> GDP-D-mannuronate + 2 NADH + 2 H+
GDP-mannose + H2O <=> GMP + D-Mannose 1-phosphate
GDP + D-Mannose 1-phosphate <=> Orthophosphate + GDP-mannose
GTP + D-Mannose 1-phosphate <=> Diphosphate + GDP-mannose
GDP-mannose + Mannan(n) <=> GDP + Mannan(n+1)
GDP-mannose <=> GDP-4-dehydro-6-deoxy-D-mannose + H2O
GDP-mannose <=> GDP-L-galactose
GDP-mannose + 1,4-beta-D-Mannan <=> GDP + 1,4-beta-D-Mannan
L-Serine + Hydrogen sulfide <=> L-Cysteine + H2O
2 L-Cysteine + NAD+ <=> L-Cystine + H+ + NADH
L-Cysteine + Oxygen <=> 3-Sulfino-L-alanine
ATP + L-Glutamate + L-Cysteine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteine
L-Cysteine + 2-Oxoglutarate <=> Mercaptopyruvate + L-Glutamate
L-Cysteine + 2-Oxoglutarate <=> Mercaptopyruvate + Glutamate
O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate
Cys-Gly + H2O <=> L-Cysteine + Glycine
L-Cysteine + Glutathione + NADP+ <=> S-Glutathionyl-L-cysteine + NADPH
L-Cysteine + Sulfite <=> Hydrogen sulfide + L-Cysteate
L-Cysteine <=> D-Cysteine
3-Aminopropanal + NAD+ + H2O <=> beta-Alanine + NADH + H+
3-Ureidopropionate + H2O <=> beta-Alanine + CO2 + Ammonia
beta-Alanopine + NAD+ + H2O <=> beta-Alanine + Pyruvate + NADH + H+
L-Alanine + 3-Oxopropanoate <=> Pyruvate + beta-Alanine
beta-Alanine + 2-Oxoglutarate <=> 3-Oxopropanoate + L-Glutamate
N-Acetyl-beta-alanine + H2O <=> Acetate + beta-Alanine
ATP + L-Lysine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-L-lysine
beta-Alanyl-L-lysine + H2O <=> beta-Alanine + L-Lysine
ATP + L-Arginine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-L-arginine
3-Guanidinopropanoate + H2O <=> beta-Alanine + Urea
beta-Alanine <=> beta-Alanyl-CoA
beta-Alanine <=> Quinolinate
beta-Alanine <=> beta-Nitropropanoate
beta-Alanine + Ammonia <=> 3-Aminopropiononitrile + 2 H2O
Propanoyl-CoA + 6 (S)-Methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 6-Deoxyerythronolide B + 7 CoA + 6 CO2 + H2O + 6 NADP+
Propanoyl-CoA + NADP+ <=> Propenoyl-CoA + NADPH + H+
ATP + Propanoate + CoA <=> ADP + Orthophosphate + Propanoyl-CoA
Propanoyl-CoA + Orthophosphate <=> Propanoyl phosphate + CoA
2-Methyl-3-oxopropanoate + CoA + NAD+ <=> Propanoyl-CoA + CO2 + NADH + H+
(S)-Methylmalonyl-CoA <=> Propanoyl-CoA + CO2
ATP + Propanoate + CoA <=> AMP + Diphosphate + Propanoyl-CoA
Propionyladenylate + CoA <=> AMP + Propanoyl-CoA
Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA
Acetyl-CoA + Propanoate <=> Acetate + Propanoyl-CoA
(S)-Methylmalonyl-CoA + Pyruvate <=> Propanoyl-CoA + Oxaloacetate
2-Methylcitrate + CoA <=> Propanoyl-CoA + Oxaloacetate + H2O
2-Hydroxyglutarate + CoA <=> Propanoyl-CoA + H2O + Glyoxylate
Propanoyl-CoA + Glyoxylate <=> L-erythro-3-Methylmalyl-CoA
(S)-Methylmalonate semialdehyde + CoA + NAD+ <=> Propanoyl-CoA + CO2 + NADH + H+
Tetrahydrofolate + NAD+ <=> Dihydrofolate + NADH + H+
Tetrahydrofolate + 2 NAD+ <=> Folate + 2 NADH + 2 H+
Tetrahydrofolate + NADP+ <=> Dihydrofolate + NADPH + H+
Tetrahydrofolate + 2 NADP+ <=> Folate + 2 NADPH + 2 H+
10-Formyltetrahydrofolate + NADP+ + H2O <=> Tetrahydrofolate + CO2 + NADPH + H+
ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate
Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate
10-Formyltetrahydrofolate + H2O <=> Formate + Tetrahydrofolate
5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine
5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine
D-Glucose 1-phosphate + H2O <=> alpha-D-Glucose + Orthophosphate
ATP + D-Glucose 1-phosphate <=> Diphosphate + ADP-glucose
ATP + D-Glucose 1-phosphate <=> ADP + alpha-D-Glucose 1,6-bisphosphate
ADP-glucose + H2O <=> AMP + D-Glucose 1-phosphate
Cellobiose + Orthophosphate <=> D-Glucose 1-phosphate + D-Glucose
Laminaribiose + Orthophosphate <=> D-Glucose + D-Glucose 1-phosphate
GTP + D-Glucose 1-phosphate <=> Diphosphate + GDP-glucose
UDP-glucose + alpha-D-Galactose 1-phosphate <=> D-Glucose 1-phosphate + UDP-alpha-D-galactose
CTP + D-Glucose 1-phosphate <=> Diphosphate + CDP-glucose
2 D-Glucose 1-phosphate + H2O <=> Maltose + 2 Orthophosphate
D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate
2 D-Glucose 1-phosphate <=> alpha-D-Glucose 1,6-bisphosphate + D-Glucose
IDP + H2O <=> IMP + Orthophosphate
ITP + Cytidine <=> IDP + CMP
UMP + H2O <=> Uridine + Orthophosphate
ATP + Uridine <=> ADP + UMP
Orotidine 5'-phosphate <=> UMP + CO2
UMP + Diphosphate <=> Uracil + 5-Phospho-alpha-D-ribose 1-diphosphate
UTP + Uridine <=> UDP + UMP
GTP + Uridine <=> GDP + UMP
P1,P4-Bis(5'-uridyl) tetraphosphate + H2O <=> UTP + UMP
ITP + Uridine <=> IDP + UMP
Uracil 5-carboxylate <=> Uracil + CO2
Cytosine + H2O <=> Uracil + Ammonia
5,6-Dihydrouracil + Oxygen <=> Uracil + Hydrogen peroxide
Uracil + Acceptor + H2O <=> Barbiturate + Reduced acceptor
5,6-Dihydrouracil + NAD+ <=> Uracil + NADH + H+
5,6-Dihydrouracil + NADP+ <=> Uracil + NADPH + H+
Anthranilate + Oxygen + NADPH + H+ <=> 2,3-Dihydroxybenzoate + Ammonia + NADP+
ATP + Anthranilate + CoA <=> AMP + Diphosphate + Anthraniloyl-CoA
2,3-Dihydroxyindole + Oxygen <=> Anthranilate + CO2
S-Adenosyl-L-methionine + Anthranilate <=> S-Adenosyl-L-homocysteine + N-Methylanthranilate
Chorismate + Ammonia <=> Anthranilate + Pyruvate + H2O
Chorismate + L-Glutamine <=> Anthranilate + Pyruvate + L-Glutamate
L-Kynurenine + H2O <=> Anthranilate + L-Alanine
Formylanthranilate + H2O <=> Formate + Anthranilate
Malonyl-CoA + Anthranilate <=> CoA + N-Malonylanthranilate
Anthranilate <=> Aniline + CO2
Anthranilate <=> 2-Formaminobenzoylacetate
2-Oxobutanoate + Orthophosphate + Oxygen <=> Propanoyl phosphate + CO2 + Hydrogen peroxide
2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+
Methyloxaloacetate <=> 2-Oxobutanoate + CO2
L-Threonine <=> 2-Oxobutanoate + Ammonia
1-Aminocyclopropane-1-carboxylate + H2O <=> 2-Oxobutanoate + Ammonia
(R)-2-Ethylmalate + CoA <=> Acetyl-CoA + H2O + 2-Oxobutanoate
O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia
2-Hydroxybutanoic acid + NAD+ <=> 2-Oxobutanoate + NADH + H+
L-Cystathionine + H2O <=> L-Cysteine + Ammonia + 2-Oxobutanoate
Dolichyl phosphate + H2O <=> Dolichol + Orthophosphate
Dolichyl diphosphate + H2O <=> Dolichyl phosphate + Orthophosphate
UDP-glucose + Dolichyl phosphate <=> UDP + Dolichyl beta-D-glucosyl phosphate
Dolichyl beta-D-glucosyl phosphate + H2O <=> Dolichyl phosphate + D-Glucose
UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol
UDP-N-acetyl-alpha-D-glucosamine + Archaeal dolichyl phosphate <=> UDP + Archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate
GDP-mannose + Dolichyl phosphate <=> GDP + Dolichyl phosphate D-mannose
Glycerone phosphate + H2O <=> Glycerone + Orthophosphate
ATP + Glycerone <=> ADP + Glycerone phosphate
Phosphoenolpyruvate + Glycerone <=> Pyruvate + Glycerone phosphate
Acyl-CoA + Glycerone phosphate <=> CoA + Acylglycerone phosphate
Erythrulose 1-phosphate <=> Glycerone phosphate + Formaldehyde
D-Glyceraldehyde 3-phosphate <=> Glycerone phosphate
Glycerone phosphate <=> Methylglyoxal + Orthophosphate
CTP + Dolichol <=> CDP + Dolichyl phosphate
PQQ + Acetaldehyde + H2O <=> PQQH2 + Acetate
ATP + Choline <=> ADP + Choline phosphate
Choline + Oxygen <=> Betaine aldehyde + Hydrogen peroxide
Acetyl-CoA + Choline <=> CoA + Acetylcholine
Choline + Acceptor <=> Betaine aldehyde + Reduced acceptor
Acetylcholine + H2O <=> Choline + Acetate
3'-Phosphoadenylyl sulfate + Choline <=> Adenosine 3',5'-bisphosphate + Choline sulfate
Choline sulfate + H2O <=> Choline + Sulfate
Acylcholine + H2O <=> Choline + Carboxylate
sn-Glycero-3-phosphocholine + H2O <=> Choline + sn-Glycerol 3-phosphate
3-Chloro-D-alanine + H2O <=> Pyruvate + Hydrochloric acid + Ammonia
Cl- + Pyruvate + Ammonia <=> 3-Chloro-L-alanine + H2O
2-Chlorobenzoate + Oxygen + NADH <=> Cl- + Catechol + NAD+ + CO2
Glycerol + NAD+ <=> Glycerone + NADH + H+
Glycerol + NAD+ <=> D-Glyceraldehyde + NADH + H+
Glycerol + NADP+ <=> Glycerone + NADPH + H+
Glycerol + NADP+ <=> D-Glyceraldehyde + NADPH + H+
Glycerol 2-phosphate + H2O <=> Glycerol + Orthophosphate
Diphosphate + Glycerol <=> Orthophosphate + sn-Glycerol 1-phosphate
Glycerol + Acceptor <=> Glycerone + Reduced acceptor
Glycerol <=> 3-Hydroxypropanal + H2O
ATP + D-Ribose 5-phosphate <=> AMP + 5-Phospho-alpha-D-ribose 1-diphosphate
ATP + D-Ribose 5-phosphate <=> ADP + D-Ribose 1,5-bisphosphate
ATP + D-Ribose <=> ADP + D-Ribose 5-phosphate
ADP + D-Ribose 5-phosphate <=> Orthophosphate + ADP-ribose
ATP + D-Ribose 5-phosphate + Ammonia <=> ADP + Orthophosphate + 5-Phosphoribosylamine
ADP-ribose + H2O <=> AMP + D-Ribose 5-phosphate
Uracil + D-Ribose 5-phosphate <=> Pseudouridine 5'-phosphate + H2O
D-Ribose 5-phosphate <=> D-Ribulose 5-phosphate
alpha-D-Ribose 1-phosphate <=> D-Ribose 5-phosphate
D-Glyceraldehyde 3-phosphate + NADP+ + H2O <=> 3-Phospho-D-glycerate + NADPH + H+
ATP + D-Glyceraldehyde <=> ADP + D-Glyceraldehyde 3-phosphate
D-Glyceraldehyde 3-phosphate + Orthophosphate + NAD+ <=> 3-Phospho-D-glyceroyl phosphate + NADH + H+
D-Glyceraldehyde 3-phosphate + Orthophosphate + NADP+ <=> 3-Phospho-D-glyceroyl phosphate + NADPH + H+
2-Dehydro-3-deoxy-6-phospho-D-galactonate <=> Pyruvate + D-Glyceraldehyde 3-phosphate
2-Deoxy-D-ribose 5-phosphate <=> D-Glyceraldehyde 3-phosphate + Acetaldehyde
D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Xylulose 5-phosphate
D-Fructose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate
D-Tagatose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate
beta-D-Fructose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate
1-(5-Phospho-D-ribosyl)-ATP + Diphosphate <=> ATP + 5-Phospho-alpha-D-ribose 1-diphosphate
5-Phosphoribosylamine + Diphosphate + L-Glutamate <=> L-Glutamine + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O
N-(5-Phospho-D-ribosyl)anthranilate + Diphosphate <=> Anthranilate + 5-Phospho-alpha-D-ribose 1-diphosphate
ATP + Biotin <=> Diphosphate + Biotinyl-5'-AMP
ATP + Biotin + CoA <=> AMP + Diphosphate + Biotinyl-CoA
Biotin amide + H2O <=> Biotin + Ammonia
Biocytin + H2O <=> Biotin + L-Lysine
Dethiobiotin + Sulfur donor + 2 S-Adenosyl-L-methionine + 2 e- + 2 H+ <=> Biotin + 2 L-Methionine + 2 5'-Deoxyadenosine
D-Ribose + NADP+ + H2O <=> D-Ribonate + NADPH + H+
Uridine + H2O <=> Uracil + D-Ribose
D-Ribose <=> D-Ribulose
(S)-Malate <=> Fumarate + H2O
N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP
3-Fumarylpyruvate + H2O <=> Fumarate + Pyruvate
N-(L-Arginino)succinate <=> Fumarate + L-Arginine
Maleic acid <=> Fumarate
L-Leucine + H2O + NAD+ <=> 4-Methyl-2-oxopentanoate + Ammonia + NADH + H+
Acetyl-CoA + L-Leucine <=> CoA + N-Acetyl-L-leucine
L-Leucine + 2-Oxoglutarate <=> 4-Methyl-2-oxopentanoate + L-Glutamate
L-Leucine <=> (3R)-beta-Leucine
ATP + alpha-D-Galactose <=> ADP + alpha-D-Galactose 1-phosphate
D-Galactose + NADH + H+ <=> Galactitol + NAD+
D-Galactose + NAD+ <=> D-Galactono-1,4-lactone + NADH + H+
D-Galactose + NADPH + H+ <=> Galactitol + NADP+
D-Galactose + NADP+ <=> D-Galactono-1,5-lactone + NADPH + H+
D-Galactose + NADP+ <=> D-Galactono-1,4-lactone + NADPH + H+
D-Galactose + Oxygen + H2O <=> D-Galactonate + Hydrogen peroxide
D-Galactose + Oxygen <=> D-galacto-Hexodialdose + Hydrogen peroxide
Lactose + H2O <=> D-Glucose + D-Galactose
Melibiose + H2O <=> D-Galactose + D-Glucose
Raffinose + H2O <=> D-Galactose + Sucrose
3-beta-D-Galactosyl-sn-glycerol + H2O <=> D-Galactose + Glycerol
Galactan + H2O <=> D-Galactose + Galactan
2 Ferricytochrome c + Nitrite + H2O <=> Nitrate + 2 Ferrocytochrome c + 2 H+
Dehydroascorbate + 2 Glutathione <=> Glutathione disulfide + Ascorbate
Cystine + 2 Glutathione <=> Glutathione disulfide + 2 Cysteine
Homocystine + 2 Glutathione <=> Glutathione disulfide + 2 Homocysteine
CoA + Glutathione disulfide <=> CoA-glutathione + Glutathione
L-Cystine + 2 Glutathione <=> Glutathione disulfide + 2 L-Cysteine
CMP-N-acetylneuraminate + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> CMP-N-glycoloylneuraminate + 2 Ferricytochrome b5 + H2O
CTP + N-Acetylneuraminate <=> Diphosphate + CMP-N-acetylneuraminate
CMP-N-acetylneuraminate <=> Colominic acid(non-reducing N- or O-acylneuraminyl residue)
CMP-N-acetylneuraminate <=> Glycolipid
ATP + (R)-5-Diphosphomevalonate <=> ADP + Orthophosphate + Isopentenyl diphosphate + CO2
Dimethylallyl diphosphate + tRNA adenine <=> Diphosphate + tRNA containing 6-isopentenyladenosine
Isopentenyl diphosphate <=> Dimethylallyl diphosphate
IMP + H2O <=> Inosine + Orthophosphate
IMP + H2O <=> 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
IMP + H2O <=> Hypoxanthine + D-Ribose 5-phosphate
IMP + NAD+ + H2O <=> Xanthosine 5'-phosphate + NADH + H+
ATP + Inosine <=> ADP + IMP
IMP + Diphosphate <=> Hypoxanthine + 5-Phospho-alpha-D-ribose 1-diphosphate
IMP + Ammonia + NADP+ <=> GMP + NADPH + H+
GTP + IMP + L-Aspartate <=> GDP + Orthophosphate + N6-(1,2-Dicarboxyethyl)-AMP
ATP + dADP <=> ADP + dATP
dATP + Pyruvate <=> dADP + Phosphoenolpyruvate
dATP + D-Glucose <=> dADP + D-Glucose 6-phosphate
dATP + D-Fructose <=> dADP + D-Fructose 6-phosphate
Methane + Oxygen + NADH + H+ <=> Methanol + NAD+ + H2O
Methane + Oxygen + NADPH + H+ <=> Methanol + NADP+ + H2O
Oxaloacetate 4-methyl ester + H2O <=> Oxaloacetate + Methanol
Monomethyl sulfate + H2O <=> Methanol + Sulfate
Methanol + 2 Ferricytochrome cL <=> Formaldehyde + 2 Ferrocytochrome cL + 2 H+
Pyridoxamine phosphate + Pyruvate <=> Pyridoxal phosphate + D-Alanine
D-Alanine + 2-Oxoglutarate <=> Pyruvate + D-Glutamate
D-Alanine + L-Glutamine <=> Ammonia + gamma-L-Glutamyl-D-alanine
ATP + 2 D-Alanine <=> ADP + Orthophosphate + D-Alanyl-D-alanine
Putrescine + Oxygen + H2O <=> 4-Aminobutyraldehyde + Ammonia + Hydrogen peroxide
N-Carbamoylputrescine + H2O <=> Putrescine + CO2 + Ammonia
S-Adenosyl-L-methionine + Putrescine <=> S-Adenosyl-L-homocysteine + N-Methylputrescine
Acetyl-CoA + Putrescine <=> CoA + N-Acetylputrescine
Putrescine + 2-Oxoglutarate <=> 4-Aminobutyraldehyde + L-Glutamate
N-Acetylputrescine + H2O <=> Acetate + Putrescine
Agmatine + H2O <=> Putrescine + Urea
L-Histidinol + 2 NAD+ + H2O <=> L-Histidine + 2 NADH + 2 H+
L-Histidine + S-Adenosyl-L-methionine <=> N(pi)-Methyl-L-histidine + S-Adenosyl-L-homocysteine
Acetyl-CoA + L-Histidine <=> CoA + N-Acetyl-L-histidine
L-Histidine + 2-Oxoglutarate <=> Imidazol-5-yl-pyruvate + L-Glutamate
L-Histidinal + H2O + NAD+ <=> L-Histidine + NADH + H+
ATP + L-Histidine + beta-Alanine <=> ADP + Orthophosphate + Carnosine
Carnosine + H2O <=> beta-Alanine + L-Histidine
L-Histidine <=> Histamine + CO2
L-Histidine <=> Urocanate + Ammonia
L-Histidine + 3 S-Adenosyl-L-methionine + H+ <=> Hercynine + 3 S-Adenosyl-L-homocysteine
Butanoyl-CoA + NAD+ <=> Crotonoyl-CoA + NADH + H+
Butanal + CoA + NAD+ <=> Butanoyl-CoA + NADH + H+
Butanal + CoA + NADP+ <=> Butanoyl-CoA + NADPH + H+
Butanoyl-CoA + Orthophosphate <=> CoA + Butanoylphosphate
Butanoyl-CoA + FAD <=> FADH2 + Crotonoyl-CoA
ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
Short-chain acyl-CoA + Electron-transferring flavoprotein <=> Short-chain trans-2,3-dehydroacyl-CoA + Reduced electron-transferring flavoprotein
Butanoyl-CoA + Acetate <=> Butanoic acid + Acetyl-CoA
3-Ethylmalate + CoA <=> Butanoyl-CoA + H2O + Glyoxylate
2-Methylpropanoyl-CoA <=> Butanoyl-CoA
myo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+
myo-Inositol + Oxygen <=> D-Glucuronate + H2O
Inositol 1-phosphate + H2O <=> myo-Inositol + Orthophosphate
myo-Inositol 4-phosphate + H2O <=> myo-Inositol + Orthophosphate
1D-myo-Inositol 3-phosphate + H2O <=> myo-Inositol + Orthophosphate
S-Adenosyl-L-methionine + myo-Inositol <=> S-Adenosyl-L-homocysteine + D-Bornesitol
S-Adenosyl-L-methionine + myo-Inositol <=> S-Adenosyl-L-homocysteine + L-Bornesitol
S-Adenosyl-L-methionine + myo-Inositol <=> S-Adenosyl-L-homocysteine + 4-O-Methyl-myo-inositol
UDP-alpha-D-galactose + myo-Inositol <=> UDP + alpha-D-Galactosyl-(1->3)-1D-myo-inositol
sn-Glycero-3-phospho-1-inositol + H2O <=> myo-Inositol + sn-Glycerol 3-phosphate
alpha-D-Galactosyl-(1->3)-1D-myo-inositol + H2O <=> myo-Inositol + D-Galactose
2 Reduced ferredoxin + NADP+ + H+ <=> 2 Oxidized ferredoxin + NADPH
2 Reduced ferredoxin + Acetyl-CoA + CO2 + 2 H+ <=> 2 Oxidized ferredoxin + Pyruvate + CoA
2 Reduced ferredoxin + Succinyl-CoA + CO2 + 2 H+ <=> 2 Oxidized ferredoxin + 2-Oxoglutarate + CoA
2 Oxidized ferredoxin + 2-Oxobutanoate + CoA <=> 2 Reduced ferredoxin + Propanoyl-CoA + CO2 + 2 H+
N-Acetyl-D-glucosamine + H2O <=> D-Glucosamine + Acetate
ATP + N-Acetyl-D-glucosamine <=> ADP + N-Acetyl-D-glucosamine 6-phosphate
N-Acetyl-alpha-D-glucosamine + NAD+ + H2O <=> N-Acetyl-D-glucosaminate + NADH + H+
N-Acetyl-D-glucosamine + Oxygen + H2O <=> N-Acetyl-D-glucosaminate + Hydrogen peroxide
Acetyl-CoA + D-Glucosamine <=> CoA + N-Acetyl-D-glucosamine
UDP-alpha-D-galactose + N-Acetyl-D-glucosamine <=> UDP + N-Acetyllactosamine
Chitin + H2O <=> N-Acetyl-D-glucosamine + Chitin
N-Acetyl-D-glucosamine <=> N-Acetyl-D-mannosamine
2,3-Dihydroxy-3-methylbutanoate <=> 3-Methyl-2-oxobutanoic acid + H2O
3-Methyl-2-oxobutanoic acid + CoA + NAD+ <=> 2-Methylpropanoyl-CoA + CO2 + NADH + H+
(R)-3,3-Dimethylmalate + NAD+ <=> 3-Methyl-2-oxobutanoic acid + CO2 + NADH + H+
L-Valine + NADP+ + H2O <=> 3-Methyl-2-oxobutanoic acid + Ammonia + NADPH + H+
alpha-Isopropylmalate + CoA <=> Acetyl-CoA + 3-Methyl-2-oxobutanoic acid + H2O
L-Valine + 2-Oxoglutarate <=> 3-Methyl-2-oxobutanoic acid + L-Glutamate
L-Valine + Pyruvate <=> 3-Methyl-2-oxobutanoic acid + L-Alanine
2-Dehydropantoate <=> 3-Methyl-2-oxobutanoic acid + Formaldehyde
5,10-Methylenetetrahydrofolate + 2 Reduced ferredoxin + 2 H+ <=> 5-Methyltetrahydrofolate + 2 Oxidized ferredoxin
5,10-Methylenetetrahydrofolate + NAD+ <=> 5,10-Methenyltetrahydrofolate + NADH
5,10-Methylenetetrahydrofolate + NADP+ <=> 5,10-Methenyltetrahydrofolate + NADPH
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+
5,10-Methylenetetrahydrofolate + D-Alanine + H2O <=> Tetrahydrofolate + 2-Methylserine
5,10-Methylenetetrahydrofolate + 3-Methyl-2-oxobutanoic acid + H2O <=> Tetrahydrofolate + 2-Dehydropantoate
GMP + H2O <=> Guanosine + Orthophosphate
ATP + Guanosine <=> ADP + GMP
GMP + Diphosphate <=> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate
ATP + Xanthosine 5'-phosphate + Ammonia <=> AMP + Diphosphate + GMP
ATP + Xanthosine 5'-phosphate + L-Glutamine + H2O <=> AMP + Diphosphate + GMP + L-Glutamate
P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O <=> GTP + GMP
GDP-glucose + H2O <=> GMP + D-Glucose 1-phosphate
3',5'-Cyclic GMP + H2O <=> GMP
Thiol + S-Adenosyl-L-methionine <=> Methyl thioether + S-Adenosyl-L-homocysteine
3'-Phosphoadenylyl sulfate + Thiol <=> Adenosine 3',5'-bisphosphate + S-Alkyl thiosulfate
Thioglucoside + H2O <=> Thiol + Sugar
4-Hydroxybenzoate <=> Phenol + CO2
S-Adenosyl-L-methionine + Phenol <=> S-Adenosyl-L-homocysteine + Anisole
UDP-glucose + Phenol <=> UDP + Aryl beta-D-glucoside
Phenol + Acetate <=> Phenyl acetate + H2O
3'-Phosphoadenylyl sulfate + Phenol <=> Adenosine 3',5'-bisphosphate + Aryl sulfate
Aryl sulfate + H2O <=> Phenol + Sulfate
Adenine + H2O <=> Hypoxanthine + Ammonia
Adenosine + H2O <=> Adenine + D-Ribose
L-Proline + NAD+ <=> 1-Pyrroline-2-carboxylate + NADH + H+
L-Proline + NAD+ <=> (S)-1-Pyrroline-5-carboxylate + NADH + H+
L-Proline + NADP+ <=> 1-Pyrroline-2-carboxylate + NADPH + H+
L-Proline + NADP+ <=> (S)-1-Pyrroline-5-carboxylate + NADPH + H+
L-Proline + 2-Oxoglutarate + Oxygen <=> Hydroxyproline + Succinate + CO2
L-Proline + Quinone <=> (S)-1-Pyrroline-5-carboxylate + Hydroquinone
L-Proline <=> D-Proline
ATP + (S)-Malate + CoA <=> ADP + Orthophosphate + L-Malyl-CoA
(S)-Malate + FAD <=> Oxaloacetate + FADH2
L-Amino acid + NAD+ + H2O <=> 2-Oxo acid + Ammonia + NADH + H+
L-Amino acid + H2O + Oxygen <=> 2-Oxo acid + Ammonia + Hydrogen peroxide
L-Amino acid + Oxygen + NADPH <=> N-Hydroxy-amino acid + NADP+ + H2O
L-Alanine + 2-Oxo acid <=> Pyruvate + L-Amino acid
Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid
N-Acyl-L-amino acid + H2O <=> Carboxylate + L-Amino acid
N-Methyl-L-amino acid + H2O + Oxygen <=> L-Amino acid + Formaldehyde + Hydrogen peroxide
L-Amino acid <=> D-Amino acid
N4-(Acetyl-beta-D-glucosaminyl)asparagine + H2O <=> N-Acetyl-D-glucosamine + L-Asparagine
L-Asparagine <=> 3-Cyano-L-alanine + H2O
Nicotinamide + H2O <=> Nicotinate + Ammonia
S-Adenosyl-L-methionine + Nicotinamide + H+ <=> S-Adenosyl-L-homocysteine + 1-Methylnicotinamide
Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide + D-Ribose 5-phosphate
Nicotinamide D-ribonucleotide + Diphosphate <=> Nicotinamide + 5-Phospho-alpha-D-ribose 1-diphosphate
Nicotinamide-beta-riboside + H2O <=> Nicotinamide + D-Ribose
Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid
Hexadecanal + CoA + NAD+ <=> Palmitoyl-CoA + NADH + H+
Palmitoyl-CoA + NADP+ <=> trans-Hexadec-2-enoyl-CoA + NADPH + H+
Palmitoyl-CoA + FAD <=> trans-Hexadec-2-enoyl-CoA + FADH2
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
Palmitoyl-CoA + L-Serine <=> 3-Dehydrosphinganine + CoA + CO2
Palmitoyl-CoA + Acceptor <=> trans-Hexadec-2-enoyl-CoA + Reduced acceptor
L-Homocysteine + H2O <=> Hydrogen sulfide + Ammonia + 2-Oxobutanoate
L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
O-Acetyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Acetate
O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate
L-Serine + L-Homocysteine <=> Cystathionine + H2O
L-Serine + L-Homocysteine <=> L-Cystathionine + H2O
S-Ribosyl-L-homocysteine <=> (S)-4,5-Dihydroxypentane-2,3-dione + L-Homocysteine
L-Homocystine + 2 Glutathione <=> 2 L-Homocysteine + Glutathione disulfide
4-Hydroxybenzaldehyde + NAD+ + H2O <=> 4-Hydroxybenzoate + NADH + H+
4-Hydroxybenzaldehyde + NADP+ + H2O <=> 4-Hydroxybenzoate + NADPH + H+
Benzoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Hydroxybenzoate + [Oxidized NADPH---hemoprotein reductase] + H2O
4-Hydroxybenzoate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + NAD+ + H2O
4-Hydroxybenzoate + Oxygen + NADH + H+ <=> Hydroquinone + CO2 + NAD+ + H2O
4-Hydroxybenzoate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + NADP+ + H2O
4-Hydroxybenzoate + Oxygen + NADPH + H+ <=> Hydroquinone + CO2 + NADP+ + H2O
ATP + 4-Hydroxybenzoate + CoA <=> AMP + Diphosphate + 4-Hydroxybenzoyl-CoA
4-Hydroxybenzoyl-CoA + H2O <=> 4-Hydroxybenzoate + CoA
4-Hydroxybenzoate + Pyruvate <=> Chorismate
4-Hydroxybenzoate + Acceptor + H2O <=> 4-Hydroxybenzaldehyde + Reduced acceptor + Oxygen
UDP-glucose + 4-Hydroxybenzoate <=> UDP + 4-(beta-D-Glucosyloxy)benzoate
4-Hydroxyphenacyl alcohol + Oxygen <=> 4-Hydroxybenzoate + Formate
4-Methoxybenzoate + Reduced acceptor + Oxygen <=> 4-Hydroxybenzoate + Formaldehyde + Acceptor + H2O
4-Chlorobenzoate + H2O <=> 4-Hydroxybenzoate + Cl- + H+
4-Hydroxybenzoate + Acetate + NADH + H+ <=> 4-Coumarate + 2 H2O + NAD+
Phosphatidylcholine + 2 H2O <=> sn-Glycero-3-phosphocholine + 2 Fatty acid
Phosphatidylcholine + H2O <=> Phosphatidate + Choline
Phosphatidylcholine + H2O <=> 1,2-Diacyl-sn-glycerol + Choline phosphate
Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Carboxylate
Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + Carboxylate
Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid
Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + Fatty acid
Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Arachidonate
Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine
Acyl-CoA + 2-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine
S-Adenosyl-L-methionine + Phosphatidyl-N-dimethylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidylcholine
CDP-choline + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylcholine
ATP + Citrate + CoA <=> ADP + Orthophosphate + (3S)-Citryl-CoA
Acetyl-CoA + Citrate <=> Acetate + (3S)-Citryl-CoA
Citrate <=> Isocitrate
Citrate <=> cis-Aconitate + H2O
ATP + D-Mannose <=> ADP + D-Mannose 6-phosphate
ITP + D-Mannose <=> IDP + D-Mannose 6-phosphate
Dolichyl phosphate D-mannose + H2O <=> Dolichyl phosphate + D-Mannose
Epimelibiose + H2O <=> D-Mannose + D-Galactose
dATP + D-Mannose <=> dADP + D-Mannose 6-phosphate
G10542 + H2O <=> D-Mannose + G10542
1,4-beta-D-Mannan + (n-1) H2O <=> n D-Mannose
Glycolaldehyde + NAD+ + H2O <=> Glycolate + NADH + H+
2-Phosphoglycolate + H2O <=> Glycolate + Orthophosphate
Glycolate + Pyruvate <=> 5-Hydroxy-2,4-dioxopentanoate + H2O
Carboxymethyloxysuccinate <=> Fumarate + Glycolate
2-Oxoaldehyde + NAD+ + H2O <=> 2-Oxo acid + NADH + H+
2-Oxoaldehyde + NADP+ + H2O <=> 2-Oxo acid + NADPH + H+
2-Oxo acid + L-Glutamate <=> alpha-Amino acid + 2-Oxoglutarate
D-Amino acid + H2O + Oxygen <=> 2-Oxo acid + Ammonia + Hydrogen peroxide
(S)-2-Hydroxyacid + Oxygen <=> 2-Oxo acid + Hydrogen peroxide
alpha-Amino acid + H2O + Acceptor <=> 2-Oxo acid + Ammonia + Reduced acceptor
L-Ornithine + 2-Oxo acid <=> L-Glutamate 5-semialdehyde + L-Amino acid
D-Amino acid + Pyruvate <=> 2-Oxo acid + D-Alanine
L-Asparagine + 2-Oxo acid <=> 2-Oxosuccinamate + L-Amino acid
Fatty acid + Oxygen + 2 Reduced rubredoxin + 2 H+ <=> omega-Hydroxy fatty acid + 2 Oxidized rubredoxin + H2O
Fatty acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> omega-Hydroxy fatty acid + [Oxidized NADPH---hemoprotein reductase] + H2O
S-Adenosyl-L-methionine + Fatty acid <=> S-Adenosyl-L-homocysteine + Fatty acid methyl ester
Glycerol + Fatty acid <=> Triacylglycerol
1-Acylglycerol + H2O <=> Glycerol + Fatty acid
2-Acylglycerol + H2O <=> Glycerol + Fatty acid
ATP + Propanoate <=> ADP + Propanoyl phosphate
ATP + Propanoate <=> Diphosphate + Propionyladenylate
(2R,3S)-2,3-Dimethylmalate <=> Propanoate + Pyruvate
ATP + Acetoacetate + CoA <=> AMP + Diphosphate + Acetoacetyl-CoA
Acetoacetyl-CoA + H2O <=> Acetoacetate + CoA
Acetoacetyl-CoA + Acetate <=> Acetoacetate + Acetyl-CoA
(S)-3-Hydroxy-3-methylglutaryl-CoA <=> Acetyl-CoA + Acetoacetate
(R)-3-Hydroxybutanoate + NAD+ <=> Acetoacetate + NADH + H+
Acetoacetate + Fumarate <=> 4-Fumarylacetoacetate + H2O
Butanoyl-CoA + Acetoacetate <=> Butanoic acid + Acetoacetyl-CoA
Acetoacetate <=> Acetone + CO2
Acetoacetate <=> 3-Butynoate + H2O
Acyl-CoA + 2-Acylglycerol <=> CoA + Diacylglycerol
Triacylglycerol + H2O <=> Diacylglycerol + Carboxylate
Phenyllactate + NAD+ <=> Phenylpyruvate + NADH + H+
Phenyllactate + NADP+ <=> Phenylpyruvate + NADPH + H+
Phenylpyruvate + Oxygen <=> 2-Hydroxyphenylacetate + CO2
Prephenate <=> Phenylpyruvate + H2O + CO2
D-Phenylalanine + H2O + Quinone <=> Phenylpyruvate + Ammonia + Hydroquinone
L-Glutamine + Phenylpyruvate <=> 2-Oxoglutaramate + L-Phenylalanine
L-Tryptophan + Phenylpyruvate <=> Indolepyruvate + L-Phenylalanine
Phenylpyruvate <=> Phenylacetaldehyde + CO2
Phenylpyruvate <=> 2-Hydroxy-3-phenylpropenoate
UTP + D-Glucuronate 1-phosphate <=> Diphosphate + UDP-glucuronate
UDP-glucuronate + ROH <=> UDP + beta-D-Glucuronoside
UDP-glucuronate <=> UDP-D-xylose + CO2
UDP-glucuronate <=> UDP-D-galacturonate
UDP-glucuronate <=> UDP-apiose + CO2
UDP-glucuronate <=> UDP-L-iduronate
D-Glycerate + NAD+ <=> Hydroxypyruvate + NADH + H+
Hydroxypyruvate + CO2 <=> Dihydroxyfumarate
D-Glycerate + NADP+ <=> Hydroxypyruvate + NADPH + H+
Hydroxypyruvate <=> Glycolaldehyde + CO2
Hydroxypyruvate <=> 2-Hydroxy-3-oxopropanoate
ATP + Carbamate <=> ADP + Carbamoyl phosphate
Carbamoyl phosphate + L-Lysine <=> Orthophosphate + L-Homocitrulline
Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate
Carbamoyl phosphate + L-Ornithine <=> Orthophosphate + L-Citrulline
Carbamoyl phosphate + Putrescine <=> Orthophosphate + N-Carbamoylputrescine
Carbamoyl phosphate <=> Cyclic amidine
5'-Methylthioadenosine + H2O <=> Adenine + 5-Methylthio-D-ribose
5'-Methylthioadenosine + Orthophosphate <=> Adenine + S-Methyl-5-thio-D-ribose 1-phosphate
Acyl-[acyl-carrier protein] + NAD+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+
Acyl-[acyl-carrier protein] + NADP+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADPH + H+
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
ATP + Long-chain fatty acid + [Protein]-L-cysteine <=> AMP + Diphosphate + [Protein]-S-(long-chain-acyl)-L-cysteine
Formamide <=> Hydrogen cyanide + H2O
Cyanohydrin <=> Cyanide ion + Aldehyde
Hydrogen cyanide + Acetaldehyde + Ammonia <=> alpha-Aminopropiononitrile + H2O
5-Methylcytosine + H2O <=> Thymine + Ammonia
Thymine + 2-Oxoglutarate + Oxygen <=> 5-Hydroxymethyluracil + Succinate + CO2
Thymine + Acceptor + H2O <=> 5-Methylbarbiturate + Reduced acceptor
5,6-Dihydrothymine + NAD+ <=> Thymine + NADH + H+
(R)-5,6-Dihydrothymine + NADP+ <=> Thymine + NADPH + H+
Agmatine + H2O <=> N-Carbamoylputrescine + Ammonia
ATP + Agmatine <=> ADP + Phosphoagmatine
Agmatine + Urea <=> Arcaine + H2O
Benzaldehyde + NAD+ + H2O <=> Benzoate + NADH + H+
Benzaldehyde + NADP+ + H2O <=> Benzoate + NADPH + H+
Benzoyl phosphate + H2O <=> Benzoate + Orthophosphate
ATP + Benzoate + CoA <=> AMP + Diphosphate + Benzoyl-CoA
5'-Benzoylphosphoadenosine + H2O <=> AMP + Benzoate
Hippurate + H2O <=> Benzoate + Glycine
Benzoylagmatine + H2O <=> Benzoate + Agmatine
Benzoate + Acetate + NADH + H+ <=> trans-Cinnamate + 2 H2O + NAD+
Benzoate <=> 3-Hydroxybenzoate
D-Xylose + NAD+ <=> D-Xylonolactone + NADH + H+
D-Xylose + NADP+ <=> D-Xylonolactone + NADPH + H+
Xylitol + NADP+ <=> D-Xylose + NADPH + H+
D-Xylose <=> D-Xylulose
D-Xylose + 1,4-beta-D-Xylan <=> 1,4-beta-D-Xylan + H2O
L-Valine + H2O + NAD+ <=> 3-Methyl-2-oxobutanoic acid + Ammonia + NADH + H+
L-Valine <=> 2-Methylpropanamine + CO2
D-Xylulose 5-phosphate + Formaldehyde <=> D-Glyceraldehyde 3-phosphate + Glycerone
ATP + Cellobiose <=> ADP + 6-Phospho-beta-D-glucosyl-(1,4)-D-glucose
Cellobiose + Oxygen <=> Cellobiono-1,5-lactone + Hydrogen peroxide
Cellobiose + Acceptor <=> Cellobiono-1,5-lactone + Reduced acceptor
Cellotriose + H2O <=> Cellobiose + D-Glucose
Cellobiose <=> 4-O-beta-D-Glucopyranosyl-D-mannose
(S)-Lactaldehyde + NAD+ + H2O <=> (S)-Lactate + NADH + H+
(S)-Lactate + Oxaloacetate <=> (S)-Malate + Pyruvate
(R)-2-O-Sulfolactate + H2O <=> (R)-Lactate + Sulfate
Lactoyl-CoA + Propanoate <=> (S)-Lactate + Propanoyl-CoA
(S)-Lactate <=> (R)-Lactate
Cholesterol + NAD+ <=> 7-Dehydrocholesterol + NADH + H+
Cholesterol + Oxygen + NADPH + H+ <=> Cholesterol-5alpha,6alpha-epoxide + NADP+ + H2O
Cholesterol + Oxygen + NADPH + H+ <=> Cholesterol-5beta,6beta-epoxide + NADP+ + H2O
Cholesterol + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 20alpha-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
Cholesterol + NADP+ <=> 7-Dehydrocholesterol + NADPH + H+
Cholesterol + NADP+ <=> Desmosterol + H+ + NADPH
Cholesterol + Oxygen <=> Cholest-4-en-3-one + Hydrogen peroxide
Cholesteryl-beta-D-glucoside + H2O <=> Cholesterol + D-Glucose
Acyl-CoA + Cholesterol <=> CoA + Cholesterol ester
Cholesterol ester + H2O <=> Cholesterol + Fatty acid
Cholesterol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 7alpha-Hydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
L-Threonine + NAD+ <=> L-2-Amino-3-oxobutanoic acid + NADH + H+
O-Phospho-L-homoserine + H2O <=> L-Threonine + Orthophosphate
L-Threonine <=> D-Threonine
ATP + Ethanolamine <=> ADP + Ethanolamine phosphate
Ethanolamine + H2O + Oxygen <=> Glycolaldehyde + Ammonia + Hydrogen peroxide
sn-Glycero-3-phosphoethanolamine + H2O <=> Ethanolamine + sn-Glycerol 3-phosphate
UTP + alpha-D-Xylose 1-phosphate <=> Diphosphate + UDP-D-xylose
UDP-D-xylose + Dolichyl phosphate <=> UDP + Dolichyl D-xylosyl phosphate
UDP-L-arabinose <=> UDP-D-xylose
UDP-D-xylose <=> Pentosan + UDP
ATP + D-Glucuronate <=> ADP + D-Glucuronate 1-phosphate
H2O + beta-D-Glucuronoside <=> D-Glucuronate + Alcohol
alpha-D-Glucuronoside + H2O <=> Alcohol + D-Glucuronate
L-Gulonate + NADP+ <=> D-Glucuronate + NADPH + H+
D-Glucuronate <=> D-Fructuronate
D-Glucuronolactone + H2O <=> D-Glucuronate
D-Glucurono-6,2-lactone + H2O <=> D-Glucuronate
L-Asparagine + Hydroxylamine <=> Ammonia + beta-L-Aspartylhydroxamate
Aromatic aldehyde + NAD+ + H2O <=> Aromatic acid + NADH + H+
Aromatic primary alcohol + NAD+ <=> Aromatic aldehyde + NADH + H+
Aromatic primary alcohol + NADP+ <=> Aromatic aldehyde + NADPH + H+
Aromatic aldehyde + Oxygen + H2O <=> Aromatic acid + Hydrogen peroxide
Aromatic aldehyde + AMP + Diphosphate + NADP+ <=> Aromatic acid + NADPH + ATP + H+
Aromatic primary alcohol + Oxygen <=> Aromatic aldehyde + Hydrogen peroxide
ATP + Cob(I)alamin <=> Triphosphate + Cobamide coenzyme
N-Acylsphingosine + H2O <=> Carboxylate + Sphingosine
N-Acylsphingosine + H2O <=> Fatty acid + Sphingosine
ATP + N-Acylsphingosine <=> ADP + Ceramide 1-phosphate
Acyl-CoA + Sphingosine <=> CoA + N-Acylsphingosine
UDP-glucose + N-Acylsphingosine <=> UDP + Glucosylceramide
Glucosylceramide + H2O <=> D-Glucose + N-Acylsphingosine
UDP-alpha-D-galactose + N-Acylsphingosine <=> UDP + Galactosylceramide
Glycosyl-N-acylsphingosine + H2O <=> Sugar + N-Acylsphingosine
CDP-ethanolamine + N-Acylsphingosine <=> CMP + Ceramide phosphoethanolamine
ATP + 2,3-Dihydroxybenzoate <=> Diphosphate + (2,3-Dihydroxybenzoyl)adenylate
(2S,3S)-2,3-Dihydro-2,3-dihydroxybenzoate + NAD+ <=> 2,3-Dihydroxybenzoate + NADH + H+
2,3-Dihydroxybenzoate + Oxygen <=> 2-Carboxy-cis,cis-muconate
2,3-Dihydroxybenzoate + Oxygen <=> 3-Carboxy-2-hydroxymuconate semialdehyde
3-Hydroxybenzoate + Reduced acceptor + Oxygen <=> 2,3-Dihydroxybenzoate + Acceptor + H2O
3-Phospho-D-glycerate + H2O <=> D-Glycerate + Orthophosphate
ATP + 3-Phospho-D-glycerate <=> ADP + 3-Phospho-D-glyceroyl phosphate
3-Phospho-D-glycerate + NAD+ <=> 3-Phosphonooxypyruvate + NADH + H+
ATP + D-Glycerate <=> ADP + 3-Phospho-D-glycerate
3-Phospho-D-glyceroyl phosphate + H2O <=> 3-Phospho-D-glycerate + Orthophosphate
2,3-Bisphospho-D-glycerate + Protein histidine <=> 3-Phospho-D-glycerate + Protein N(tau)-phospho-L-histidine
GTP + 3-Phospho-D-glycerate <=> GDP + 3-Phospho-D-glyceroyl phosphate
2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate
D-Glucono-1,5-lactone + H2O <=> D-Gluconic acid
beta-D-Glucose + NAD+ <=> D-Glucono-1,5-lactone + NADH + H+
beta-D-Glucose + NADP+ <=> D-Glucono-1,5-lactone + NADPH + H+
beta-D-Glucose + Oxygen <=> D-Glucono-1,5-lactone + Hydrogen peroxide
ATP + D-Ribulose 5-phosphate <=> ADP + D-Ribulose 1,5-bisphosphate
D-Ribitol 5-phosphate + NAD+ <=> D-Ribulose 5-phosphate + NADH + H+
D-Ribitol 5-phosphate + NADP+ <=> D-Ribulose 5-phosphate + NADPH + H+
ATP + D-Ribulose <=> ADP + D-Ribulose 5-phosphate
6-Phospho-D-gluconate + NADP+ <=> D-Ribulose 5-phosphate + CO2 + NADPH + H+
D-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate
D-Arabinose 5-phosphate <=> D-Ribulose 5-phosphate
Nucleoside triphosphate + H2O <=> Nucleotide + Diphosphate
Isoflurophate + H2O <=> Diisopropyl phosphate + Hydrofluoric acid
UDP-alpha-D-galactose + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + alpha-D-Galactosyl-diphosphoundecaprenol
UDP-N-acetyl-D-galactosamine <=> Glycolipid
D-Gluconic acid <=> 2-Dehydro-3-deoxy-D-gluconate + H2O
D-Altronate <=> 2-Dehydro-3-deoxy-D-gluconate + H2O
ATP + 2-Dehydro-3-deoxy-D-gluconate <=> ADP + 2-Dehydro-3-deoxy-6-phospho-D-gluconate
2-Dehydro-3-deoxy-D-gluconate + NAD+ <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate + NADH + H+
2-Dehydro-3-deoxy-D-gluconate + NADP+ <=> (4S,5S)-4,5-Dihydroxy-2,6-dioxohexanoate + NADPH + H+
2-Amino-2-deoxy-D-gluconate <=> 2-Dehydro-3-deoxy-D-gluconate + Ammonia
ATP + dAMP <=> ADP + dADP
dATP + Cytidine <=> dADP + CMP
dATP + Uridine <=> dADP + UMP
Acetone + NADPH + H+ <=> Propan-2-ol + NADP+
Acetone cyanohydrin <=> Hydrogen cyanide + Acetone
Maltose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate
Acetyl-CoA + Maltose <=> CoA + Acetyl-maltose
Maltose <=> alpha,alpha-Trehalose
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
Succinyl-CoA + Oxalate <=> Succinate + Oxalyl-CoA
Adenosine + H2O <=> Inosine + Ammonia
Adenosine + Orthophosphate <=> Adenine + alpha-D-Ribose 1-phosphate
3'-AMP + H2O <=> Adenosine + Orthophosphate
N-Carbamoylsarcosine + H2O <=> Sarcosine + CO2 + Ammonia
N,N-Dimethylglycine + H2O + Oxygen <=> Sarcosine + Formaldehyde + Hydrogen peroxide
N,N-Dimethylglycine + Tetrahydrofolate + Electron-transferring flavoprotein <=> Sarcosine + 5,10-Methylenetetrahydrofolate + Reduced electron-transferring flavoprotein
Creatine + H2O <=> Sarcosine + Urea
ATP + Thymidine <=> ADP + dTMP
ADP + Thymidine <=> AMP + dTMP
dTMP + H2O <=> Thymidine + Orthophosphate
Thymidine + Orthophosphate <=> Thymine + 2-Deoxy-D-ribose 1-phosphate
AMP + Thymidine <=> Adenosine + dTMP
ATP + D-Arabinose <=> ADP + D-Arabinose 5-phosphate
D-Arabinose + NAD+ <=> D-Arabinono-1,4-lactone + NADH + H+
D-Arabinose + NADP+ <=> D-Arabinono-1,4-lactone + NADPH + H+
3-Deoxy-D-manno-octulosonate <=> Pyruvate + D-Arabinose
D-Arabinose <=> D-Ribulose
D-Glutamate + Peptide <=> D-Glutamyl-peptide
D-Glutamine + H2O <=> D-Glutamate + Ammonia
Pyridoxamine phosphate + 2-Oxoglutarate <=> Pyridoxal phosphate + D-Glutamate
N-Acyl-D-glutamate + H2O <=> Carboxylate + D-Glutamate
D-Phenylalanine + 2-Oxoglutarate <=> Phenylpyruvate + D-Glutamate
D-Glutamate <=> 5-Oxo-D-proline + H2O
N-Methyl-L-alanine + H2O + NADP+ <=> Pyruvate + Methylamine + NADPH + H+
ATP + L-Glutamate + Methylamine <=> ADP + Orthophosphate + N5-Methyl-L-glutamine
Methylamine + L-Glutamate <=> Ammonia + N-Methyl-L-glutamate
N-Methyl-2-oxoglutaramate + H2O <=> Methylamine + 2-Oxoglutarate
Dimethylamine + H2O + Electron-transferring flavoprotein <=> Methylamine + Formaldehyde + Reduced electron-transferring flavoprotein
Methylguanidine + H2O <=> Methylamine + Urea
Arachidonate + 2 Oxygen <=> Prostaglandin G2
Arachidonate + Oxygen <=> 15(S)-HPETE
Arachidonate + Oxygen <=> 8(R)-HPETE
Arachidonate + Oxygen <=> 5(S)-HPETE
Arachidonate + Oxygen <=> 12(S)-HPETE
ATP + Arachidonate + CoA <=> AMP + Diphosphate + Arachidonyl-CoA
Arachidonate + Reduced acceptor + 2 Oxygen <=> Prostaglandin H2 + Acceptor + H2O
ATP + beta-D-Glucose <=> ADP + beta-D-Glucose 6-phosphate
alpha-D-Glucose <=> beta-D-Glucose
3-Oxopropanoate + NAD+ + H2O <=> Malonate + NADH + H+
3-Oxopropanoate + NADP+ + H2O <=> Malonate + NADPH + H+
3-Hydroxypropanoate + NAD+ <=> 3-Oxopropanoate + NADH + H+
3-Oxopropanoate + Nitrite + Hydrogen peroxide <=> 3-aci-Nitropropanoate + Oxygen + H2O
3-Oxopropanoate <=> Propynoate + H2O
p-Coumaroyl-CoA + 3 Malonyl-CoA <=> Naringenin chalcone + 4 CoA + 3 CO2
3 Malonyl-CoA + p-Coumaroyl-CoA <=> 4 CoA + Resveratrol + 4 CO2
4-Hydroxycinnamyl aldehyde + CoA + NADP+ <=> p-Coumaroyl-CoA + NADPH + H+
ATP + 4-Coumarate + CoA <=> AMP + Diphosphate + p-Coumaroyl-CoA
p-Coumaroyl-CoA + Agmatine <=> p-Coumaroylagmatine + CoA
Adenylyl sulfate + ATP <=> Sulfate + P1,P4-Bis(5'-adenosyl)tetraphosphate
Adenylyl sulfate + Ammonia <=> Adenosine 5'-phosphoramidate + Sulfate
Acetyl phosphate + L-Lysine <=> Orthophosphate + N6-Acetyl-L-lysine
D-Xylulose 5-phosphate + Orthophosphate <=> Acetyl phosphate + D-Glyceraldehyde 3-phosphate + H2O
Acyl-carrier protein + H2O <=> Pantetheine 4'-phosphate + Apo-[acyl-carrier-protein]
Acetyl-CoA + Acyl-carrier protein <=> CoA + Acetyl-[acyl-carrier protein]
CoA + Apo-[acyl-carrier-protein] <=> Adenosine 3',5'-bisphosphate + Acyl-carrier protein
Malonyl-CoA + Acyl-carrier protein <=> CoA + Malonyl-[acyl-carrier protein]
3-Dehydroshikimate <=> 3,4-Dihydroxybenzoate + H2O
3-Hydroxybenzoate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + NADP+ + H2O
3,4-Dihydroxybenzoate + Oxygen + NADH + H+ <=> Benzene-1,2,4-triol + CO2 + NAD+ + H2O
3,4-Dihydroxybenzoate + Oxygen + NADPH + H+ <=> Benzene-1,2,4-triol + CO2 + NADP+ + H2O
3,4-Dihydroxybenzoate + Oxygen <=> 3-Carboxy-cis,cis-muconate
3,4-Dihydroxybenzoate + Oxygen <=> 4-Carboxy-2-hydroxymuconate semialdehyde
(3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ <=> 3,4-Dihydroxybenzoate + CO2 + NADH + H+
3,4-Dihydroxyphthalate <=> 3,4-Dihydroxybenzoate + CO2
4,5-Dihydroxyphthalate <=> 3,4-Dihydroxybenzoate + CO2
4-Sulfobenzoate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + Sulfite + NAD+
3,4-Dihydroxybenzoate <=> Gallate
ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate
Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Ribose 5-phosphate + D-Xylulose 5-phosphate
4-Hydroxybutanoic acid + NAD+ <=> Succinate semialdehyde + NADH + H+
4-Hydroxy-2-oxo-heptanedioate <=> Succinate semialdehyde + Pyruvate
Succinate semialdehyde + Pyruvate <=> 2,4-Dihydroxyhept-2-enedioate
4-Aminobutanoate + 2-Oxoglutarate <=> Succinate semialdehyde + L-Glutamate
2-(Acetamidomethylene)succinate + 2 H2O <=> Acetate + Succinate semialdehyde + Ammonia + CO2
Succinate semialdehyde + Hydrogen cyanide + Ammonia <=> gamma-Amino-gamma-cyanobutanoate + H2O
4-Methyl-2-oxopentanoate + CoA + NAD+ <=> 3-Methylbutanoyl-CoA + CO2 + NADH + H+
4-Methyl-2-oxopentanoate + CO2 <=> (2S)-2-Isopropyl-3-oxosuccinate
ATP + 10-Formyltetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + (6R)-10-Formyltetrahydropteroyldiglutamate
5,10-Methenyltetrahydrofolate + H2O <=> 10-Formyltetrahydrofolate + H+
Dimethylallyl diphosphate + L-Tryptophan <=> Diphosphate + 4-(3-Methylbut-2-enyl)-L-tryptophan
Dimethylallyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Geranyl diphosphate
Dimethylallyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Neryl diphosphate
3-Phospho-D-glyceroyl phosphate + D-Glucose 1-phosphate <=> 3-Phospho-D-glycerate + alpha-D-Glucose 1,6-bisphosphate
3-Phospho-D-glyceroyl phosphate <=> 2,3-Bisphospho-D-glycerate
dCMP + H2O <=> dUMP + Ammonia
dCMP + H2O <=> Deoxycytidine + Orthophosphate
ATP + dCMP <=> ADP + dCDP
ATP + Deoxycytidine <=> ADP + dCMP
dCDP + H2O <=> dCMP + Orthophosphate
dCTP + H2O <=> dCMP + Diphosphate
5,10-Methylenetetrahydrofolate + H2O + dCMP <=> Tetrahydrofolate + 5-Hydroxymethyldeoxycytidylate
5,10-Methylenetetrahydrofolate + dCMP <=> Dihydrofolate + Deoxy-5-methylcytidylate
Guanine + H2O <=> Xanthine + Ammonia
Guanosine + H2O <=> Guanine + D-Ribose
Lactose + H2O <=> alpha-D-Glucose + D-Galactose
Lactose + Acceptor <=> 3-Ketolactose + Reduced acceptor
Hypotaurine + NAD+ + H2O <=> Taurine + NADH + H+
L-Cysteate <=> Taurine + CO2
Tauropine + NAD+ + H2O <=> Taurine + Pyruvate + NADH + H+
Taurine + 2-Oxoglutarate <=> Sulfoacetaldehyde + L-Glutamate
Taurine + H2O + 2 Ferricytochrome c <=> Sulfoacetaldehyde + Ammonia + 2 Ferrocytochrome c + 2 H+
Taurine + L-Arginine <=> Taurocyamine + L-Ornithine
(5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine
ATP + Butanoic acid <=> ADP + Butanoylphosphate
Butanoic acid + NAD+ <=> 2-Butenoate + NADH + H+
5'-Butyrylphosphoinosine + H2O <=> IMP + Butanoic acid
L-Sorbose + NADP+ <=> 5-Dehydro-D-fructose + NADPH + H+
L-Sorbose + Oxygen <=> 5-Dehydro-D-fructose + Hydrogen peroxide
L-Sorbose + Acceptor <=> 5-Dehydro-D-fructose + Reduced acceptor
D-Sorbitol + Acceptor <=> L-Sorbose + Reduced acceptor
Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+
Pyruvate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2
2-Oxoglutarate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2
3-Methyl-2-oxobutanoic acid + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2
4-Methyl-2-oxopentanoate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine + CO2
Hexadecanoic acid + 2 Hydrogen peroxide <=> Pentadecanal + CO2 + 3 H2O
Hexadecanal + NAD+ + H2O <=> Hexadecanoic acid + NADH + H+
Hexadecanoic acid + Protein <=> Palmitoyl-protein + H2O
Hexadecanoyl-[acp] + H2O <=> Acyl-carrier protein + Hexadecanoic acid
Pyridoxal + NAD+ <=> 4-Pyridoxolactone + NADH + H+
Pyridoxine + NADP+ <=> Pyridoxal + NADPH + H+
Pyridoxal + Oxygen + H2O <=> 4-Pyridoxate + Hydrogen peroxide
Pyridoxamine + H2O + Oxygen <=> Pyridoxal + Ammonia + Hydrogen peroxide
Pyridoxine + Oxygen <=> Pyridoxal + Hydrogen peroxide
Pyridoxamine + Pyruvate <=> Pyridoxal + L-Alanine
Pyridoxamine + Oxaloacetate <=> Pyridoxal + L-Aspartate
5-O-(1-Carboxyvinyl)-3-phosphoshikimate <=> Chorismate + Orthophosphate
Chorismate <=> Prephenate
Chorismate + L-Glutamine <=> 4-Amino-4-deoxychorismate + L-Glutamate
Chorismate <=> Isochorismate
Isomaltose + H2O <=> alpha-D-Glucose + D-Glucose
Nicotinate + NADP+ + H2O <=> 6-Hydroxynicotinate + NADPH + H+
S-Adenosyl-L-methionine + Nicotinate <=> S-Adenosyl-L-homocysteine + N-Methylnicotinate
UDP-glucose + Nicotinate <=> UDP + N-Glucosylnicotinate
Nicotinate + Glycine + ATP <=> Nicotinurate + AMP + Diphosphate
Nicotinate D-ribonucleotide + Diphosphate + ADP + Orthophosphate <=> Nicotinate + 5-Phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + H+
Nicotinate <=> 2-Methyleneglutarate
Prephenate + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + CO2 + NADH + H+
Prephenate + NADP+ <=> 3-(4-Hydroxyphenyl)pyruvate + CO2 + NADPH + H+
Oxaloacetate + L-Arogenate <=> L-Aspartate + Prephenate
Riboflavin + H2O <=> Ribitol + Lumichrome
Dimethylbenzimidazole <=> Riboflavin
(R)-Lactaldehyde + NAD+ + H2O <=> (R)-Lactate + NADH + H+
(R)-S-Lactoylglutathione + H2O <=> Glutathione + (R)-Lactate
ATP + D-Gluconic acid <=> ADP + 6-Phospho-D-gluconate
D-Gluconic acid + NAD+ <=> 5-Dehydro-D-gluconate + NADH + H+
D-Gluconic acid + NADP+ <=> 2-Keto-D-gluconic acid + NADPH + H+
D-Gluconic acid + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+
D-Gluconic acid + FAD <=> 2-Keto-D-gluconic acid + FADH2
D-Gluconic acid + Acceptor <=> 2-Keto-D-gluconic acid + Reduced acceptor
D-Glycerate + NAD+ <=> 2-Hydroxy-3-oxopropanoate + NADH + H+
D-Glycerate + NADP+ <=> 2-Hydroxy-3-oxopropanoate + NADPH + H+
2-Phospho-D-glycerate + H2O <=> D-Glycerate + Orthophosphate
D-Glycerate + NAD+ + CO2 <=> 2-Hydroxy-3-oxosuccinate + NADH + H+
D-Glycerate + NADP+ + CO2 <=> 2-Hydroxy-3-oxosuccinate + NADPH + H+
(R,R)-Tartaric acid <=> D-Glycerate + CO2
D-Glyceraldehyde + NAD+ + H2O <=> D-Glycerate + NADH + H+
ATP + L-Arabinose <=> ADP + beta-L-Arabinose 1-phosphate
L-Arabinose + NAD+ <=> L-Arabinono-1,4-lactone + NADH + H+
L-Arabitol + NAD+ <=> L-Arabinose + NADH + H+
L-Arabitol + NADP+ <=> L-Arabinose + NADPH + H+
beta-L-Arabinoside + H2O <=> Alcohol + L-Arabinose
L-Arabinose <=> L-Ribulose
Arabinan + H2O <=> Arabinan + L-Arabinose
Benzyl alcohol + NAD+ <=> Benzaldehyde + NADH + H+
alpha-Oxo-benzeneacetic acid <=> Benzaldehyde + CO2
L-threo-3-Phenylserine <=> Glycine + Benzaldehyde
Mandelonitrile <=> Hydrogen cyanide + Benzaldehyde
Hypoxanthine + NAD+ + H2O <=> Xanthine + NADH + H+
Hypoxanthine + Oxygen + H2O <=> Xanthine + Hydrogen peroxide
Inosine + H2O <=> Hypoxanthine + D-Ribose
ATP + L-Homoserine <=> ADP + O-Phospho-L-homoserine
L-Homoserine + NAD+ <=> L-Aspartate 4-semialdehyde + NADH + H+
L-Homoserine + NADP+ <=> L-Aspartate 4-semialdehyde + NADPH + H+
Acetyl-CoA + L-Homoserine <=> CoA + O-Acetyl-L-homoserine
Succinyl-CoA + L-Homoserine <=> CoA + O-Succinyl-L-homoserine
(3S)-3-Hydroxyacyl-CoA + NAD+ <=> 3-Oxoacyl-CoA + NADH + H+
(3R)-3-Hydroxyacyl-CoA + NADP+ <=> 3-Oxoacyl-CoA + NADPH + H+
Succinyl-CoA + 3-Oxo acid <=> Succinate + 3-Oxoacyl-CoA
Ethylene glycol + NAD+ <=> Glycolaldehyde + NADH + H+
2-Dehydro-3-deoxy-D-xylonate <=> Pyruvate + Glycolaldehyde
2-Dehydro-3-deoxy-L-arabinonate <=> Pyruvate + Glycolaldehyde
L-Xylulose 1-phosphate <=> Glycerone phosphate + Glycolaldehyde
ATP + alpha-D-Glucose <=> ADP + alpha-D-Glucose 6-phosphate
D-Sorbitol + NADP+ <=> alpha-D-Glucose + NADPH + H+
alpha-D-Glucose 6-phosphate + H2O <=> alpha-D-Glucose + Orthophosphate
Starch + H2O <=> D-Glucose + Starch
Dextrin + H2O <=> D-Glucose + Dextrin
Dihydrobiopterin + NADH + H+ <=> Tetrahydrobiopterin + NAD+
Dihydrobiopterin + NADPH + H+ <=> Tetrahydrobiopterin + NADP+
Tetrahydrobiopterin + L-Phenylalanine + Oxygen <=> Dihydrobiopterin + L-Tyrosine + H2O
CDP-diacylglycerol + H2O <=> CMP + Phosphatidate
Arachidonyl-CoA + CDP-acylglycerol <=> CoA + CDP-diacylglycerol
CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol
CDP-diacylglycerol + L-Serine <=> CMP + Phosphatidylserine
CDP-diacylglycerol + sn-Glycerol 3-phosphate <=> CMP + Phosphatidylglycerophosphate
CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol
N-Acetylneuraminate + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> N-Glycoloyl-neuraminate + 2 Ferricytochrome b5 + H2O
N-Acetylneuraminate + Orthophosphate <=> N-Acetyl-D-mannosamine + Phosphoenolpyruvate + H2O
N-Acetylneuraminate 9-phosphate + H2O <=> N-Acetylneuraminate + Orthophosphate
Acetyl-CoA + N-Acetylneuraminate <=> CoA + N-Acetyl-4-O-acetylneuraminate
Acetyl-CoA + N-Acetylneuraminate <=> CoA + N-Acetyl-7-O-acetylneuraminate
Acetyl-CoA + N-Acetylneuraminate <=> CoA + N-Acetyl-9-O-acetylneuraminate
N-Acetyl-O-acetylneuraminate + H2O <=> N-Acetylneuraminate + Acetate
N-Acetylneuraminate <=> N-Acetyl-D-mannosamine + Pyruvate
Tetrahydrobiopterin + 2 NADP+ <=> Biopterin + 2 NADPH + 2 H+
Tetrahydrobiopterin + NADP+ <=> 6-Lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+
Tetrahydrobiopterin + L-Tryptophan + Oxygen <=> 5-Hydroxy-L-tryptophan + Dihydrobiopterin + H2O
Tetrahydrobiopterin + L-Tyrosine + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + Dihydrobiopterin + H2O
D-Mannitol 1-phosphate + NADP+ <=> D-Mannose 6-phosphate + NADPH + H+
D-Mannose 6-phosphate <=> D-Mannose 1-phosphate
D-Mannose 6-phosphate <=> beta-D-Fructose 6-phosphate
Amylose + Orthophosphate <=> Amylose + D-Glucose 1-phosphate
Sucrose + Amylose <=> D-Fructose + Amylose
Maltodextrin <=> 1-alpha-D-[(1->4)-alpha-D-Glucosyl](n-1)-alpha-D-glucopyranoside
D-Erythrose 4-phosphate + NAD+ + H2O <=> 4-Phospho-D-erythronate + NADH + H+
Phosphoenolpyruvate + D-Erythrose 4-phosphate + H2O <=> 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + Orthophosphate
Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + beta-D-Fructose 6-phosphate
Sedoheptulose 1,7-bisphosphate <=> Glycerone phosphate + D-Erythrose 4-phosphate
beta-D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Xylulose 5-phosphate
Androstenedione + Reduced acceptor + Oxygen <=> Testololactone + Acceptor + H2O
5alpha-Androstane-3,17-dione + Acceptor <=> Androstenedione + Reduced acceptor
5beta-Androstane-3,17-dione + NADP+ <=> H+ + NADPH + Androstenedione
Testosterone + NAD+ <=> Androstenedione + NADH + H+
Dehydroepiandrosterone + NAD+ <=> Androstenedione + NADH + H+
Testosterone + NADP+ <=> Androstenedione + NADPH + H+
Androstenedione + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Hydroxyandrost-4-ene-3,17-dione + [Oxidized NADPH---hemoprotein reductase] + H2O
Androstenedione + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha-Hydroxyandrost-4-ene-3,17-dione + [Oxidized NADPH---hemoprotein reductase] + H2O
ATP + Sedoheptulose 7-phosphate <=> ADP + Sedoheptulose 1,7-bisphosphate
ATP + Sedoheptulose <=> ADP + Sedoheptulose 7-phosphate
Sedoheptulose 1,7-bisphosphate + H2O <=> Sedoheptulose 7-phosphate + Orthophosphate
Acetyl-CoA + Hydrogen sulfide <=> CoA + Thioacetate
Methanethiol + Oxygen + H2O <=> Hydrogen sulfide + Formaldehyde + Hydrogen peroxide
RCH2NH2 + H2O + Oxygen <=> Aldehyde + Ammonia + Hydrogen peroxide
RCH2NH2 + H2O + Acceptor <=> Aldehyde + Ammonia + Reduced acceptor
dGTP + H2O <=> dGMP + Diphosphate
dGTP + H2O <=> Deoxyguanosine + Triphosphate
ATP + dGDP <=> ADP + dGTP
dGTP + Pyruvate <=> dGDP + Phosphoenolpyruvate
ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA
4-Aminobenzoate <=> Aniline + CO2
3'-Phosphoadenylyl sulfate + Aniline <=> Adenosine 3',5'-bisphosphate + Benzenamine sulfate
Anilide + H2O <=> Carboxylate + Aniline
Inosine + Orthophosphate <=> Hypoxanthine + alpha-D-Ribose 1-phosphate
(S)-Dihydroorotate + NADP+ <=> Orotate + NADPH + H+
(S)-Dihydroorotate + Fumarate <=> Orotate + Succinate
(S)-Dihydroorotate + Quinone <=> Orotate + Hydroquinone
(S)-Dihydroorotate + NAD+ <=> Orotate + H+ + NADH
Orotidine 5'-phosphate + Diphosphate <=> Orotate + 5-Phospho-alpha-D-ribose 1-diphosphate
Quinate + NAD+ <=> 3-Dehydroquinate + NADH + H+
Quinate + PQQ <=> PQQH2 + 3-Dehydroquinate
D-Cysteine + H2O <=> Hydrogen sulfide + Ammonia + Pyruvate
Thiosulfate + 2 Glutathione + H+ <=> Sulfite + Glutathione disulfide + Hydrogen sulfide
Uridine + Orthophosphate <=> Uracil + alpha-D-Ribose 1-phosphate
3'-UMP + H2O <=> Uridine + Orthophosphate
Cytidine + H2O <=> Uridine + Ammonia
Deoxyuridine + 2-Oxoglutarate + Oxygen <=> Uridine + Succinate + CO2
dGTP + Uridine <=> dGDP + UMP
ATP + Creatine <=> ADP + Phosphocreatine
Phosphocreatine + H2O <=> Creatine + Orthophosphate
S-Adenosyl-L-methionine + Guanidinoacetate <=> S-Adenosyl-L-homocysteine + Creatine
Creatinine + H2O <=> Creatine
ADP-ribose + H2O <=> alpha-D-Ribose 1-phosphate + AMP
N(omega)-(ADP-D-ribosyl)-L-arginine + H2O <=> L-Arginine + ADP-ribose
gamma-Amino-gamma-cyanobutanoate + 2 H2O <=> Glutamate + Ammonia
ATP + Kanamycin A <=> ADP + Kanamycin A 3'-phosphate
Acetyl-CoA + Kanamycin B <=> CoA + N6'-Acetylkanamycin-B
CTP + Choline phosphate <=> Diphosphate + CDP-choline
CDP-choline + N-Acylsphingosine <=> CMP + Sphingomyelin
Ribitol + 2 Ferricytochrome c <=> D-Ribulose + 2 Ferrocytochrome c + 2 H+
Ribitol + NAD+ <=> D-Ribulose + NADH + H+
Xylitol + NAD+ <=> D-Xylulose + NADH + H+
D-Xylulose <=> D-Lyxose
Isocitrate + NADP+ <=> Oxalosuccinate + NADPH + H+
Isocitrate <=> cis-Aconitate + H2O
ATP + L-Xylulose <=> ADP + L-Xylulose 5-phosphate
ATP + L-Xylulose <=> ADP + L-Xylulose 1-phosphate
L-Arabitol + NAD+ <=> L-Xylulose + NADH + H+
Xylitol + NADP+ <=> L-Xylulose + NADPH + H+
3-Dehydro-L-gulonate <=> L-Xylulose + CO2
L-Xylulose <=> L-Lyxose
Oxalyl-CoA <=> Formyl-CoA + CO2
ATP + Pyridoxine <=> ADP + Pyridoxine phosphate
Pyridoxine + Oxygen <=> Isopyridoxal + Hydrogen peroxide
Pyridoxine + Orthophosphate <=> Pyridoxine phosphate + H2O
UDP-glucose + Pyridoxine <=> UDP + 5'-O-beta-D-Glucosylpyridoxine
Pyridoxine <=> 1-Deoxy-D-xylulose + 4-Hydroxy-L-threonine
Spermidine + Oxygen + H2O <=> 1,3-Diaminopropane + 4-Aminobutyraldehyde + Hydrogen peroxide
Spermidine + Acceptor + H2O <=> 1,3-Diaminopropane + 4-Aminobutyraldehyde + Reduced acceptor
ATP + Glutathione + Spermidine <=> ADP + Orthophosphate + Glutathionylspermidine
Glutathionylspermidine + H2O <=> Glutathione + Spermidine
Putrescine + Spermidine <=> sym-Homospermidine + 1,3-Diaminopropane
S-Adenosylmethioninamine + Putrescine <=> 5'-Methylthioadenosine + Spermidine
(S)-Carnitine + NAD+ <=> 3-Dehydrocarnitine + NADH + H+
L-Carnitinamide + H2O <=> L-Carnitine + Ammonia + H+
Palmitoyl-CoA + L-Carnitine <=> CoA + L-Palmitoylcarnitine
O-Acylcarnitine + H2O <=> Fatty acid + L-Carnitine
Sphingosine + ATP <=> Sphingosine 1-phosphate + ADP
UDP-alpha-D-galactose + Sphingosine <=> UDP + Psychosine
CDP-choline + Sphingosine <=> CMP + Sphingosyl-phosphocholine
Trithionate + H2O <=> Thiosulfate + Sulfate
Thiosulfate + Cyanide ion <=> Sulfite + Thiocyanate
2-Oxoadipate + NADH + H+ <=> 2-Hydroxyadipate + NAD+
2-Oxoadipate + CoA + NAD+ <=> Glutaryl-CoA + CO2 + NADH + H+
Homoisocitrate + NAD+ <=> 2-Oxoadipate + CO2 + NADH + H+
Oxaloglutarate <=> 2-Oxoadipate + CO2
2-Oxoadipate + Ammonia + NAD+ <=> 2-Aminomuconate + NADH + H+ + H2O
2-Oxoadipate + Ammonia + NADP+ <=> 2-Aminomuconate + NADPH + H+ + H2O
L-2-Aminoadipate + 2-Oxoglutarate <=> 2-Oxoadipate + L-Glutamate
2-Oxoadipate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine + CO2
Caffeic aldehyde + CoA + NADP+ <=> Caffeoyl-CoA + NADPH + H+
S-Adenosyl-L-methionine + Caffeoyl-CoA <=> S-Adenosyl-L-homocysteine + Feruloyl-CoA
ATP + Caffeate + CoA <=> AMP + Diphosphate + Caffeoyl-CoA
Caffeoyl-CoA + Putrescine <=> CoA + N-Caffeoylputrescine
Caffeoyl-CoA + Quinate <=> CoA + Chlorogenate
Caffeoyl-CoA + Isocitrate <=> CoA + 2-Caffeoylisocitrate
GTP + L-Fucose 1-phosphate <=> Diphosphate + GDP-L-fucose
Palmitoyl-CoA + Glycoprotein <=> CoA + N-Palmitoylglycoprotein
ATP + L-Citrulline + L-Aspartate <=> AMP + Diphosphate + N-(L-Arginino)succinate
L-Kynurenine + 2-Oxoglutarate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + L-Glutamate
L-Kynurenine + Glyoxylate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + Glycine
L-Formylkynurenine + H2O <=> Formate + L-Kynurenine
L-Kynurenine + Oxygen + NADPH + H+ <=> 3-Hydroxy-L-kynurenine + NADP+ + H2O
ATP + D-Glucosamine <=> ADP + D-Glucosamine 6-phosphate
D-Glucosamine + Oxygen + H2O <=> 2-Amino-2-deoxy-D-gluconate + Hydrogen peroxide
N-Sulfo-D-glucosamine + H2O <=> D-Glucosamine + Sulfate
ITP + D-Glucosamine <=> IDP + D-Glucosamine 6-phosphate
dATP + D-Glucosamine <=> dADP + D-Glucosamine 6-phosphate
D-Glucosamine + D-Glucosaminide <=> D-Glucosaminide + H2O
ATP + Deoxyguanosine <=> ADP + dGMP
dGMP + H2O <=> Deoxyguanosine + Orthophosphate
Deoxyguanosine + Orthophosphate <=> Guanine + 2-Deoxy-D-ribose 1-phosphate
S-Adenosyl-L-methionine + Indolepyruvate <=> S-Adenosyl-L-homocysteine + (R)-3-(Indol-3-yl)-2-oxobutyrate
S-Adenosyl-L-methionine + Indolepyruvate <=> S-Adenosyl-L-homocysteine + 3-Methylindolepyruvate
Indolepyruvate <=> Indole-3-acetaldehyde + CO2
(S)-3-Hydroxybutanoyl-CoA + NAD+ <=> Acetoacetyl-CoA + NADH + H+
(S)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(R)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-Hydroxy-3-methylglutaryl-CoA + CoA <=> Acetyl-CoA + H2O + Acetoacetyl-CoA
ATP + D-Galacturonate <=> ADP + 1-Phospho-alpha-D-galacturonate
D-Galacturonate + NAD+ + H2O <=> D-Galactarate + NADH + H+
Pectate + H2O <=> D-Galacturonate + Pectate
D-Galacturonate <=> D-Tagaturonate
D-Galacturonate <=> D-Galacturonolactone + H2O
4-Aminobutyraldehyde + NADP+ + H2O <=> 4-Aminobutanoate + NADPH + H+
4-Aminobutanoate + Acetate <=> 4-Acetamidobutanoate + H2O
L-Arginine + 4-Aminobutanoate <=> L-Ornithine + 4-Guanidinobutanoate
4-Guanidinobutanoate + H2O <=> 4-Aminobutanoate + Urea
ATP + L-Histidine + 4-Aminobutanoate <=> ADP + Orthophosphate + Homocarnosine
Homocarnosine + H2O <=> 4-Aminobutanoate + L-Histidine
(S)-Dihydroorotate + H2O <=> N-Carbamoyl-L-aspartate
UDP-glucose + Lipopolysaccharide <=> UDP + D-Glucosyllipopolysaccharide
UDP-glucose + Lipopolysaccharide <=> UDP + alpha-D-Glucosyllipopolysaccharide
UDP-N-acetyl-alpha-D-glucosamine + Lipopolysaccharide <=> UDP + N-Acetyl-D-glucosaminyllipopolysaccharide
UDP-alpha-D-galactose + Lipopolysaccharide <=> UDP + 3-alpha-D-Galactosyl-[lipopolysaccharide glucose]
Long-chain alcohol + H2O + 2 NAD+ <=> Long-chain carboxylate + 2 NADH + 2 H+
Acyl-CoA + Long-chain alcohol <=> CoA + Long-chain ester
2 Reduced rubredoxin + NAD+ + H+ <=> 2 Oxidized rubredoxin + NADH
2 Reduced rubredoxin + NADP+ + H+ <=> 2 Oxidized rubredoxin + NADPH
Geranyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + trans,trans-Farnesyl diphosphate
Geranyl diphosphate + H2O <=> (-)-endo-Fenchol + Diphosphate
Geranyl diphosphate + H2O <=> Sabinene hydrate + Diphosphate
(+)-Bornyl diphosphate <=> Geranyl diphosphate
(6E)-8-Oxogeranial <=> Iridodial
Geranyl diphosphate <=> Myrcene + Diphosphate
Geranyl diphosphate <=> Terpinolene + Diphosphate
Geranyl diphosphate <=> Camphene + Diphosphate
Geranyl diphosphate <=> (S)-Limonene + Diphosphate
dATP + Thioredoxin disulfide + H2O <=> ATP + Thioredoxin
Thioredoxin + NADP+ <=> Thioredoxin disulfide + NADPH + H+
dADP + Thioredoxin disulfide + H2O <=> Thioredoxin + ADP
dUDP + Thioredoxin disulfide + H2O <=> Thioredoxin + UDP
dGDP + Thioredoxin disulfide + H2O <=> GDP + Thioredoxin
dGTP + Thioredoxin disulfide + H2O <=> GTP + Thioredoxin
Thioredoxin + 3'-Phosphoadenylyl sulfate <=> Thioredoxin disulfide + Sulfite + Adenosine 3',5'-bisphosphate
dCTP + Thioredoxin disulfide + H2O <=> CTP + Thioredoxin
dUTP + Thioredoxin disulfide + H2O <=> UTP + Thioredoxin
dCDP + Thioredoxin disulfide + H2O <=> Thioredoxin + CDP
L-Methionine + Thioredoxin disulfide + H2O <=> L-Methionine S-oxide + Thioredoxin
O-Acetyl-L-homoserine + Thiosulfate + Thioredoxin + H+ <=> L-Homocysteine + Sulfite + Thioredoxin disulfide + Acetate
Phosphatidylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + sn-Glycerol 3-phosphate
Phosphatidylglycerophosphate + H2O <=> Phosphatidylglycerol + Orthophosphate
Phosphatidylglycerol + CDP-diacylglycerol <=> Cardiolipin + CMP
6-Phospho-D-gluconate + NAD+ <=> 6-Phospho-2-dehydro-D-gluconate + NADH + H+
6-Phospho-D-gluconate + NADP+ <=> 6-Phospho-2-dehydro-D-gluconate + NADPH + H+
D-Glucono-1,5-lactone 6-phosphate + H2O <=> 6-Phospho-D-gluconate
6-Phospho-D-gluconate <=> 2-Dehydro-3-deoxy-6-phospho-D-gluconate + H2O
S-Adenosyl-L-methionine + Ethanolamine phosphate <=> S-Adenosyl-L-homocysteine + N-Methylethanolamine phosphate
CTP + Ethanolamine phosphate <=> Diphosphate + CDP-ethanolamine
Long-chain aldehyde + NAD+ + H2O <=> Long-chain carboxylate + NADH + H+
N-Long-chain-fatty-acyl-L-glutamate + H2O <=> Long-chain carboxylate + L-Glutamate
N-(Long-chain-acyl)ethanolamine + H2O <=> Long-chain carboxylate + Ethanolamine
Wax ester + H2O <=> Long-chain alcohol + Long-chain carboxylate
3-Hydroxy-2-methylpropanoate + NAD+ <=> 2-Methyl-3-oxopropanoate + NADH + H+
(R)-3-Amino-2-methylpropanoate + Pyruvate <=> 2-Methyl-3-oxopropanoate + L-Alanine
Phosphatidylethanolamine + H2O <=> Ethanolamine + Phosphatidate
Phosphatidylethanolamine + H2O <=> 1,2-Diacyl-sn-glycerol + Ethanolamine phosphate
Phosphatidylethanolamine + H2O <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid
Phosphatidylethanolamine + H2O <=> 2-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid
Phosphatidylserine <=> Phosphatidylethanolamine + CO2
S-Adenosyl-L-methionine + Phosphatidylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine
CDP-ethanolamine + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylethanolamine
Acetyl-CoA + D-Glucosamine 6-phosphate <=> CoA + N-Acetyl-D-glucosamine 6-phosphate
N-Acetyl-D-glucosamine 6-phosphate + H2O <=> D-Glucosamine 6-phosphate + Acetate
alpha-D-Glucosamine 1-phosphate <=> D-Glucosamine 6-phosphate
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Geranylgeranyl diphosphate
Geranylgeranyl diphosphate + 3 H+ + 3 NADPH <=> Phytyl diphosphate + 3 NADP+
Geranylgeranyl diphosphate <=> Casbene + Diphosphate
2 Geranylgeranyl diphosphate <=> Diphosphate + Prephytoene diphosphate
Geranylgeranyl diphosphate <=> ent-Copalyl diphosphate
ATP + D-Fructose 1-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate
Diphosphate + beta-D-Fructose 6-phosphate <=> Orthophosphate + beta-D-Fructose 1,6-bisphosphate
3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
3,4-Dihydroxy-L-phenylalanine + 2-Oxoglutarate <=> 3-(3,4-Dihydroxyphenyl)pyruvate + L-Glutamate
3,4-Dihydroxy-L-phenylalanine + L-Tyrosine + Oxygen <=> Dopaquinone + 3,4-Dihydroxy-L-phenylalanine + H2O
3,4-Dihydroxy-L-phenylalanine <=> Dopamine + CO2
(R)-Mevalonate + CoA + 2 NAD+ <=> (S)-3-Hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+
(R)-Mevalonate + CoA + 2 NADP+ <=> (S)-3-Hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
(S)-3-Hydroxy-3-methylglutaryl-CoA + H2O <=> CoA + 3-Hydroxy-3-methylglutarate
Succinyl-CoA + 3-Hydroxy-3-methylglutarate <=> Succinate + (S)-3-Hydroxy-3-methylglutaryl-CoA
(S)-3-Hydroxy-3-methylglutaryl-CoA <=> 3-Methylglutaconyl-CoA + H2O
N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetyl-D-mannosamine 6-phosphate
dAMP + H2O <=> Deoxyadenosine + Orthophosphate
ATP + Deoxyadenosine <=> ADP + dAMP
ATP + dGMP <=> ADP + dGDP
dGTP + Cytidine <=> dGDP + CMP
dTDP + H2O <=> dTMP + Orthophosphate
ATP + dTDP <=> ADP + dTTP
ATP + dTMP <=> ADP + dTDP
dTTP + H2O <=> dTDP + Orthophosphate
dTTP + Cytidine <=> dTDP + CMP
dTTP + Uridine <=> dTDP + UMP
ATP + dUMP <=> ADP + dUDP
ATP + Deoxyuridine <=> ADP + dUMP
dUTP + H2O <=> dUMP + Diphosphate
dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP
dUMP + H2O <=> Deoxyuridine + Orthophosphate
Xanthine + NAD+ + H2O <=> Urate + NADH + H+
Urate + Oxygen + H2O <=> 5-Hydroxyisourate + Hydrogen peroxide
Xanthine + H2O + Oxygen <=> Urate + Hydrogen peroxide
Starch + H2O <=> Dextrin + Starch
Starch + H2O <=> Amylose + alpha-D-Glucose
Amylose <=> Starch
Starch + Orthophosphate <=> Amylose + D-Glucose 1-phosphate
Starch <=> Dextrin + Maltose
UDP-glucose + Sterol <=> UDP + Sterol 3-beta-D-glucoside
Phosphatidylcholine + Sterol <=> 1-Acyl-sn-glycero-3-phosphocholine + Steryl ester
Steryl ester + H2O <=> Sterol + Fatty acid
Sterol <=> (S)-2,3-Epoxysqualene
UDP-glucose + Zeatin <=> UDP + O-beta-D-Glucosylzeatin
UDP-D-xylose + Zeatin <=> UDP + O-beta-D-Xylosylzeatin
Sucrose + Dextran <=> D-Fructose + Dextran
Dextran + Amylose <=> Dextran + Amylose
3'-Phosphoadenylyl sulfate + [Heparan sulfate]-glucosamine <=> Adenosine 3',5'-bisphosphate + [Heparan sulfate]-N-sulfoglucosamine
Retinal + NAD+ + H2O <=> Retinoate + NADH + H+
Retinol + NAD+ <=> Retinal + NADH + H+
Retinal + Oxygen + H2O <=> Retinoate + Hydrogen peroxide
Retinal <=> 11-cis-Retinal
Retinal <=> Metarhodopsin
Retinal <=> Iodopsin + hn
Retinal <=> all-trans-Dehydroretinal
Steroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 21-Hydroxysteroid + [Oxidized NADPH---hemoprotein reductase] + H2O
Steroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxysteroid + [Oxidized NADPH---hemoprotein reductase] + H2O
Thiamine + 2 Oxygen + H2O <=> Thiamine acetic acid + 2 Hydrogen peroxide
Thiamine + H2O <=> 4-Amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-Hydroxyethyl)-4-methylthiazole + H+
ATP + Thiamine <=> ADP + Thiamin monophosphate
Thiamin monophosphate + H2O <=> Thiamine + Orthophosphate
ATP + Xylitol <=> ADP + Xylitol 5-phosphate
Cytidine + H2O <=> Cytosine + D-Ribose
Palmitoyl-CoA + Dolichol <=> CoA + Dolichyl palmitate
Barbiturate + H2O <=> 3-Oxo-3-ureidopropanoate
Xanthine + H2O <=> 5-Ureido-4-imidazole carboxylate
Xanthosine 5'-phosphate + Diphosphate <=> Xanthine + 5-Phospho-alpha-D-ribose 1-diphosphate
Xanthosine + H2O <=> Xanthine + D-Ribose
S-Adenosyl-L-methionine + Carnosine <=> S-Adenosyl-L-homocysteine + beta-Alanyl-N(pi)-methyl-L-histidine
Guanosine + H2O <=> Xanthosine + Ammonia
Guanosine + Orthophosphate <=> Guanine + alpha-D-Ribose 1-phosphate
Guanosine 3'-phosphate + H2O <=> Guanosine + Orthophosphate
Histamine + Oxygen + H2O <=> Imidazole-4-acetaldehyde + Ammonia + Hydrogen peroxide
Histamine + Acetyl-CoA <=> 4-(beta-Acetylaminoethyl)imidazole + CoA
S-Adenosyl-L-methionine + Histamine <=> S-Adenosyl-L-homocysteine + N-Methylhistamine
Quercetin + Oxygen <=> 2-Protocatechoylphloroglucinolcarboxylate + CO
S-Adenosyl-L-methionine + Quercetin <=> S-Adenosyl-L-homocysteine + 3-O-Methylquercetin
UDP-glucose + Quercetin <=> UDP + Quercetin 3-O-glucoside
3'-Phosphoadenylyl sulfate + Quercetin <=> Adenosine 3',5'-bisphosphate + Quercetin 3-sulfate
Taxifolin + 2-Oxoglutarate + Oxygen <=> Quercetin + Succinate + CO2 + H2O
Ubiquinol + NAD+ <=> Ubiquinone + NADH + H+
Quinone + Succinate <=> Hydroquinone + Fumarate
Ubiquinol + Nitrate <=> Ubiquinone + Nitrite + H2O
D-Mannitol 1-phosphate + H2O <=> Mannitol + Orthophosphate
GDP-glucose + D-Glucose 6-phosphate <=> GDP + alpha,alpha'-Trehalose 6-phosphate
Penicillin + H2O <=> Carboxylate + 6-Aminopenicillanate
Pyrimidine 5'-nucleotide + H2O <=> Pyrimidine + D-Ribose 5-phosphate + H+
Pyrimidine nucleoside + H2O <=> Pyrimidine + D-Ribose + H+
Tryptamine + H2O + Oxygen <=> Indole-3-acetaldehyde + Ammonia + Hydrogen peroxide
S-Adenosyl-L-methionine + Tryptamine <=> S-Adenosyl-L-homocysteine + N-Methyltryptamine
(-)-Menthol + NADP+ <=> (-)-Menthone + NADPH + H+
(-)-Menthol + Oxygen + NADPH + H+ <=> p-Menthane-3,8-diol + NADP+ + H2O
UDP-glucose + (-)-Menthol <=> UDP + (-)-Menthyl O-beta-D-glucoside
3'-Phosphoadenylyl sulfate + Chondroitin <=> Adenosine 3',5'-bisphosphate + Chondroitin 4-sulfate
3'-Phosphoadenylyl sulfate + Chondroitin <=> Adenosine 3',5'-bisphosphate + Chondroitin 6-sulfate
N-Acyl-D-aspartate + H2O <=> Carboxylate + D-Aspartate
UDP-N-acetyl-D-galactosamine + Polypeptide <=> UDP + N-Acetyl-alpha-D-galactosaminyl-polypeptide
ATP + Polyphosphate <=> ADP + Polyphosphate
Polyphosphate + D-Glucose <=> Polyphosphate + D-Glucose 6-phosphate
Dolichyl diphosphate + Polyphosphate <=> Dolichyl phosphate + Polyphosphate
Polyphosphate + beta-D-Glucose <=> Polyphosphate + beta-D-Glucose 6-phosphate
3-Phospho-D-glyceroyl phosphate + Polyphosphate <=> 3-Phospho-D-glycerate + Polyphosphate
Polyphosphate + alpha-D-Glucose <=> Polyphosphate + alpha-D-Glucose 6-phosphate
N-Carbamoyl-D-amino acid + H2O <=> D-Amino acid + Ammonia + CO2
Acetyl-CoA + D-Amino acid <=> CoA + N-Acetyl-D-amino acid
N-Acyl-D-amino acid + H2O <=> Carboxylate + D-Amino acid
Coniferyl aldehyde + CoA + NADP+ <=> Feruloyl-CoA + NADPH + H+
ATP + Ferulate + CoA <=> AMP + Diphosphate + Feruloyl-CoA
Feruloyl-CoA + Quinate <=> CoA + 5-O-Feruloylquinic acid
L-Isoleucine + NAD+ + H2O <=> (S)-3-Methyl-2-oxopentanoic acid + Ammonia + NADH + H+
L-Isoleucine + H2O + Oxygen <=> (S)-3-Methyl-2-oxopentanoic acid + Ammonia + Hydrogen peroxide
L-Isoleucine + 2-Oxoglutarate <=> (S)-3-Methyl-2-oxopentanoic acid + L-Glutamate
L-Valine + (S)-3-Methyl-2-oxopentanoic acid <=> 3-Methyl-2-oxobutanoic acid + L-Isoleucine
L-Pipecolate + NAD+ <=> Delta1-Piperideine-2-carboxylate + NADH + H+
L-Pipecolate + NADP+ <=> Delta1-Piperideine-2-carboxylate + NADPH + H+
L-Pipecolate + Oxygen <=> (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + Hydrogen peroxide
L-Pipecolate + FAD <=> FADH2 + (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
L-Pipecolate + Acceptor <=> (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + Reduced acceptor
20alpha-Hydroxy-4-pregnen-3-one + NAD+ <=> Progesterone + NADH + H+
5alpha-Pregnane-3,20-dione + NADP+ <=> Progesterone + NADPH + H+
20alpha-Hydroxy-4-pregnen-3-one + NADP+ <=> Progesterone + NADPH + H+
Progesterone + Oxygen + NADPH + H+ <=> Testosterone acetate + NADP+ + H2O
Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxyprogesterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Progesterone + Reduced acceptor + Oxygen <=> Testosterone acetate + Acceptor + H2O
Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycorticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Progesterone + Reduced acceptor + Oxygen <=> 11alpha-Hydroxyprogesterone + Acceptor + H2O
5beta-Pregnane-3,20-dione + Acceptor <=> Progesterone + Reduced acceptor
Pregnenolone + NAD+ <=> Progesterone + NADH + H+
Progesterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 11beta-Hydroxyprogesterone + 2 Oxidized ferredoxin + H2O
Progesterone + NADPH + H+ <=> 5beta-Pregnane-3,20-dione + NADP+
Sinapoyl aldehyde + CoA + NADP+ <=> Sinapoyl-CoA + NADPH + H+
ATP + Sinapate + CoA <=> AMP + Diphosphate + Sinapoyl-CoA
Stearoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Oleoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Stearoyl-CoA + Malonyl-CoA + 2 NADPH + 2 H+ <=> Eicosanoyl-CoA + CO2 + 2 NADP+ + CoA + H2O
ATP + Streptomycin <=> ADP + Streptomycin 6-phosphate
ATP + Streptomycin <=> Diphosphate + 3''-Adenylylstreptomycin
ATP + Streptomycin <=> ADP + Streptomycin 3''-phosphate
Streptomycin 6-phosphate + H2O <=> Streptomycin + Orthophosphate
Cyclohexanone + NADH + H+ <=> Cyclohexanol + NAD+
Cyclohexanone + Oxygen + NADPH + H+ <=> epsilon-Caprolactone + NADP+ + H2O
(1-Hydroxycyclohexan-1-yl)acetyl-CoA <=> Acetyl-CoA + Cyclohexanone
Cyclohexylamine + Oxygen + H2O <=> Cyclohexanone + Hydrogen peroxide + Ammonia
Cyclohexanone + Acceptor <=> Cyclohex-2-enone + Reduced acceptor
Dihydrofolate + NAD+ <=> Folate + NADH + H+
Dihydrofolate + NADP+ <=> Folate + NADPH + H+
ATP + Dihydropteroate + L-Glutamate <=> ADP + Orthophosphate + Dihydrofolate
ATP + Formate + Dihydrofolate <=> ADP + Orthophosphate + 10-Formyldihydrofolate
Phosphatidate + H2O <=> 1,2-Diacyl-sn-glycerol + Orthophosphate
ATP + 1,2-Diacyl-sn-glycerol <=> ADP + Phosphatidate
Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA
Acyl-CoA + 2-Acyl-sn-glycerol 3-phosphate <=> CoA + Phosphatidate
cis-Aconitate <=> Itaconate + CO2
trans-Aconitate <=> cis-Aconitate
ATP + (R)-Mevalonate <=> ADP + (R)-5-Phosphomevalonate
(R)-Mevalonate + NAD+ <=> Mevaldate + NADH + H+
(R)-Mevalonate + NADP+ <=> Mevaldate + NADPH + H+
3'-Phosphopolynucleotide + H2O <=> Polynucleotide + Orthophosphate
5'-Phosphopolynucleotide + H2O <=> Polynucleotide + Orthophosphate
Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid
Triacylglycerol + CoA <=> 1,2-Diacyl-sn-glycerol + Acyl-CoA
Phenylpropanoate + NAD+ <=> trans-Cinnamate + NADH + H+
trans-Cinnamate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Coumarate + [Oxidized NADPH---hemoprotein reductase] + H2O
trans-Cinnamate + Oxygen + NADPH + H+ <=> trans-2-Hydroxycinnamate + NADP+ + H2O
ATP + trans-Cinnamate + CoA <=> AMP + Diphosphate + Cinnamoyl-CoA
UDP-glucose + trans-Cinnamate <=> UDP + trans-Cinnamoyl beta-D-glucoside
Propane-1,2-diol + NAD+ <=> (S)-Lactaldehyde + NADH + H+
(S)-Propane-1,2-diol + NAD+ <=> (S)-Lactaldehyde + NADH + H+
Propane-1,2-diol + NADP+ <=> (S)-Lactaldehyde + NADPH + H+
(S)-Lactaldehyde + NADP+ <=> Methylglyoxal + NADPH + H+
2-Dehydro-3-deoxy-L-rhamnonate <=> (S)-Lactaldehyde + Pyruvate
L-Fuculose 1-phosphate <=> Glycerone phosphate + (S)-Lactaldehyde
L-Rhamnulose 1-phosphate <=> Glycerone phosphate + (S)-Lactaldehyde
Prostaglandin H2 + NADPH + H+ <=> Prostaglandin F2alpha + NADP+
Prostaglandin H2 <=> Prostaglandin E2
Prostaglandin H2 <=> Prostaglandin D2
Prostaglandin H2 <=> Prostaglandin I2
Prostaglandin H2 <=> Thromboxane A2
5,6-Dihydrouracil + H2O <=> 3-Ureidopropionate
5-Aminolevulinate + Pyruvate <=> 4,5-Dioxopentanoate + L-Alanine
5-Aminolevulinate <=> (S)-4-Amino-5-oxopentanoate
5-Aminopentanamide + H2O <=> 5-Aminopentanoate + Ammonia
5-Aminopentanoate + 2-Oxoglutarate <=> 5-Oxopentanoate + L-Glutamate
5-Acetamidopentanoate + H2O <=> Acetate + 5-Aminopentanoate
Secondary alcohol + Oxygen <=> Ketone + Hydrogen peroxide
2-Dehydro-3-deoxy-L-arabinonate <=> 2,5-Dioxopentanoate + H2O
5-Dehydro-4-deoxy-D-glucarate <=> 2,5-Dioxopentanoate + H2O + CO2
1-Pyrroline-4-hydroxy-2-carboxylate + H2O <=> 2,5-Dioxopentanoate + Ammonia
Alkane + 2 Reduced rubredoxin + Oxygen + 2 H+ <=> 2 Oxidized rubredoxin + Primary alcohol + H2O
N-Acetylornithine + L-Glutamate <=> L-Ornithine + N-Acetyl-L-glutamate
N-Acetylornithine + 2-Oxoglutarate <=> N-Acetyl-L-glutamate 5-semialdehyde + L-Glutamate
L-5-Carboxymethylhydantoin + H2O <=> N-Carbamoyl-L-aspartate
N-Formimino-L-glutamate + H2O <=> L-Glutamate + Formamide
N-Formimino-L-glutamate + H2O <=> N-Formyl-L-glutamate + Ammonia
5-Formiminotetrahydrofolate + L-Glutamate <=> Tetrahydrofolate + N-Formimino-L-glutamate
4-Imidazolone-5-propanoate + H2O <=> N-Formimino-L-glutamate
5-Methyltetrahydrofolate + Co(I) corrinoid protein + H+ <=> Methyl-Co(III) corrinoid protein + Tetrahydrofolate
L-Aspartate 4-semialdehyde + Orthophosphate + NADP+ <=> 4-Phospho-L-aspartate + NADPH + H+
L-2,4-Diaminobutanoate + Pyruvate <=> L-Aspartate 4-semialdehyde + L-Alanine
Nicotinamide-beta-riboside + Orthophosphate <=> Nicotinamide + alpha-D-Ribose 1-phosphate
Nicotinate D-ribonucleoside + Orthophosphate <=> Nicotinate + alpha-D-Ribose 1-phosphate + H+
Cytidine + Orthophosphate <=> Cytosine + alpha-D-Ribose 1-phosphate
Xanthosine + Orthophosphate <=> Xanthine + alpha-D-Ribose 1-phosphate
Pyrimidine nucleoside + Orthophosphate <=> Pyrimidine + alpha-D-Ribose 1-phosphate + H+
Folinic acid <=> 5,10-Methenyltetrahydrofolate + H2O
ATP + Folinic acid + H+ <=> ADP + Orthophosphate + 5,10-Methenyltetrahydrofolate
5-Formiminotetrahydrofolate + H+ <=> 5,10-Methenyltetrahydrofolate + Ammonia
ATP + trans,trans-Farnesyl diphosphate <=> ADP + Farnesyl triphosphate
trans,trans-Farnesyl diphosphate <=> Pentalenene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Trichodiene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Aristolochene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Nerolidyl diphosphate
trans,trans-Farnesyl diphosphate <=> delta-Cadinene + Diphosphate
N6-(L-1,3-Dicarboxypropyl)-L-lysine + NAD+ + H2O <=> L-Glutamate + L-2-Aminoadipate 6-semialdehyde + NADH + H+
N6-(L-1,3-Dicarboxypropyl)-L-lysine + NADP+ + H2O <=> L-Glutamate + L-2-Aminoadipate 6-semialdehyde + NADPH + H+
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O <=> L-2-Aminoadipate 6-semialdehyde
(1R,2S)-1-Hydroxypropane-1,2,3-tricarboxylate <=> (1S,2S)-1-Hydroxypropane-1,2,3-tricarboxylate
Nucleoside triphosphate + H2O <=> NDP + Orthophosphate
Nucleoside triphosphate + Pyruvate <=> NDP + Phosphoenolpyruvate
Nucleoside triphosphate + Deoxycytidine <=> NDP + dCMP
Nicotinamide D-ribonucleotide + H2O <=> Nicotinate D-ribonucleotide + Ammonia
Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate
ATP + Nicotinamide-beta-riboside <=> ADP + Nicotinamide D-ribonucleotide
dCTP + H2O <=> dUTP + Ammonia
ATP + dCDP <=> ADP + dCTP
dCTP + Uridine <=> dCDP + UMP
dTTP + D-Glucose 1-phosphate <=> Diphosphate + dTDP-glucose
dTTP + alpha-D-Galactose 1-phosphate <=> Diphosphate + dTDP-galactose
dUTP + H2O <=> dUDP + Orthophosphate
ATP + dUDP <=> ADP + dUTP
dUTP + Uridine <=> dUDP + UMP
Chitin + n H2O <=> Chitosan + n Acetate
Chitin + H2O <=> Chitobiose + Chitin
UDP-N-acetyl-alpha-D-glucosamine + Chitin <=> UDP + Chitin
Haloacetate + H2O <=> Glycolate + Halide
1-Haloalkane + H2O <=> Primary alcohol + Halide
Indole + Oxygen <=> 2-Formylaminobenzaldehyde
Indole + Oxygen + NADPH + H+ <=> Indoxyl + H2O + NADP+
Indoleglycerol phosphate <=> Indole + D-Glyceraldehyde 3-phosphate
N-D-Ribosylpurine + H2O <=> Purine + D-Ribose
Acetoin + NAD+ <=> Diacetyl + NADH + H+
(S,S)-Butane-2,3-diol + NAD+ <=> Acetoin + NADH + H+
Acetoin + D-Ribose 5-phosphate <=> Acetaldehyde + 1-Deoxy-D-altro-heptulose 7-phosphate
Estradiol-17alpha + NAD+ <=> Estrone + NADH + H+
Estradiol-17alpha + NADP+ <=> Estrone + NADPH + H+
3'-Phosphoadenylyl sulfate + Estrone <=> Adenosine 3',5'-bisphosphate + Estrone 3-sulfate
19-Oxoandrost-4-ene-3,17-dione + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Estrone + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O
Estradiol-17beta + NAD+ <=> Estrone + NADH + H+
Estradiol-17beta + NADP+ <=> Estrone + NADPH + H+
Estrone + H+ + Oxygen + NADH <=> 2-Hydroxyestrone + NAD+ + H2O
Estrone + H+ + Oxygen + NADPH <=> 2-Hydroxyestrone + NADP+ + H2O
Estrone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxyestrone + NADP+ + H2O
Estrone + UDP-glucuronate <=> Estrone glucuronide + UDP
Urethane + H2O <=> Ethanol + CO2 + Ammonia
Pectate + H2O <=> Digalacturonate + Pectate
Pectate <=> 4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate + Pectate
Pectin + n H2O <=> n Methanol + Pectate
2 Hydroquinone + Oxygen <=> 2 p-Benzoquinone + 2 H2O
2 Quinone + NADPH + H+ <=> 2 Semiquinone + NADP+
Cellobiose + Quinone <=> Cellobiono-1,5-lactone + Hydroquinone
Acyl-CoA + Retinol <=> CoA + Retinyl ester
Palmitoyl-CoA + Retinol <=> CoA + Retinyl palmitate
Retinyl palmitate + H2O <=> Retinol + Hexadecanoic acid
Retinol <=> 11-cis-Retinol
3'-CMP + H2O <=> Cytidine + Orthophosphate
dCTP + Cytidine <=> dCDP + CMP
dUTP + Cytidine <=> dUDP + CMP
Ecdysone + Oxygen <=> 3-Dehydroecdysone + Hydrogen peroxide
Ecdysone + Reduced acceptor + Oxygen <=> 20-Hydroxyecdysone + Acceptor + H2O
Palmitoyl-CoA + Ecdysone <=> CoA + Ecdysone palmitate
Propane-1,2-diol <=> Propanal + H2O
Propane-1-ol + NAD+ <=> Propanal + NADH + H+
L-Serine + Pyrazole <=> 3-(Pyrazol-1-yl)-L-alanine + H2O
S-Adenosyl-L-methionine + 5-Hydroxyferulic acid methyl ester <=> S-Adenosyl-L-homocysteine + Sinapate
UDP-glucose + Sinapate <=> UDP + 1-O-Sinapoyl-beta-D-glucose
Sinapine + H2O <=> Sinapate + Choline
Tyramine + H2O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide
Tyramine + Oxygen + NADH + H+ <=> Dopamine + NAD+ + H2O
S-Adenosyl-L-methionine + Tyramine <=> S-Adenosyl-L-homocysteine + N-Methyltyramine
Feruloyl-CoA + Tyramine <=> CoA + N-Feruloyltyramine
Acetyl-CoA + Aniline <=> CoA + Acetanilide
UDP-glucose + Aniline <=> UDP + N-D-Glucosylarylamine
2 UDP-glucuronate + Bilirubin <=> 2 UDP + Bilirubin beta-diglucuronide
Bilirubin + NAD+ <=> Biliverdin + NADH + H+
Bilirubin + NADP+ <=> Biliverdin + NADPH + H+
2 Bilirubin + Oxygen <=> 2 Biliverdin + 2 H2O
Carnitine + NAD+ <=> 3-Dehydrocarnitine + NADH + H+
Acetyl-CoA + Carnitine <=> CoA + O-Acetylcarnitine
4-Trimethylammoniobutanoate + 2-Oxoglutarate + Oxygen <=> Carnitine + Succinate + CO2
Carnitine <=> 2-Methylcholine + CO2
5-Oxopentanoate + NAD+ + H2O <=> Glutarate + NADH + H+
ATP + Glutarate + CoA <=> ADP + Orthophosphate + Glutaryl-CoA
ATP + Itaconate + CoA <=> ADP + Orthophosphate + Itaconyl-CoA
GTP + Itaconate + CoA <=> GDP + Orthophosphate + Itaconyl-CoA
ITP + Itaconate + CoA <=> IDP + Orthophosphate + Itaconyl-CoA
Succinyl-CoA + Itaconate <=> Succinate + Itaconyl-CoA
L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
L-Cystine + Sulfate <=> S-Sulfo-L-cysteine + L-Cysteine
Raffinose + H2O <=> Melibiose + D-Fructose
alpha-D-Galactosyl-(1->3)-1D-myo-inositol + Sucrose <=> myo-Inositol + Raffinose
ATP + Shikimate <=> ADP + Shikimate 3-phosphate
Shikimate + NADP+ <=> 3-Dehydroshikimate + NADPH + H+
Shikimate + PQQ <=> 3-Dehydroshikimate + PQQH2
p-Coumaroyl-CoA + Shikimate <=> CoA + 4-Coumaroylshikimate
Questin + Oxygen + NADPH + H+ <=> Demethylsulochrin + NADP+
Ubiquitin C-terminal thiolester + H2O <=> Ubiquitin + Thiol
(R)-Malate <=> Maleic acid + H2O
ADP-glucose + Protein <=> ADP + alpha-D-Glucosyl-protein
ADP-glucose + Amylose <=> ADP + Amylose
Allantoate + H2O <=> (S)-Ureidoglycolate + Urea
Allantoate + H2O <=> (S)-Ureidoglycine + Ammonia + CO2
(S)-Allantoin + H2O <=> Allantoate
CDP-glucose <=> CDP-4-dehydro-6-deoxy-D-glucose + H2O
D-Xylonolactone + H2O <=> D-Xylonate
D-Xylono-1,4-lactone + H2O <=> D-Xylonate
D-Xylonate <=> 2-Dehydro-3-deoxy-D-xylonate + H2O
ATP + Erythritol <=> ADP + D-Erythritol 4-phosphate
Nucleoside triphosphate + Gentamicin <=> Diphosphate + 2''-Nucleotidylgentamicin
L-Cysteate + 2-Oxoglutarate <=> 3-Sulfopyruvate + L-Glutamate
L-Cysteate + NADH + H+ <=> 3-Sulfino-L-alanine + H2O + NAD+
Quercitrin + H2O <=> L-Rhamnose + Quercetin
L-Rhamnose <=> L-Rhamnulose
L-Rhamnose <=> L-Rhamnofuranose
ATP + L-Ribulose <=> ADP + L-Ribulose 5-phosphate
L-Arabitol + NAD+ <=> L-Ribulose + NADH + H+
Naringenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eriodictyol + [Oxidized NADPH---hemoprotein reductase] + H2O
Naringenin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Pentahydroxyflavanone + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Naringenin + 2-Oxoglutarate + Oxygen <=> Dihydrokaempferol + Succinate + CO2
Naringenin + 2-Oxoglutarate + Oxygen <=> Apigenin + Succinate + CO2 + H2O
Naringenin <=> Naringenin chalcone
3 Malonyl-CoA + Benzoyl-CoA <=> 4 CoA + 2,4,6-Trihydroxybenzophenone + 3 CO2
Benzoyl-CoA + Oxygen + NADPH + H+ <=> 3-Hydroxybenzoyl-CoA + NADP+ + H2O
alpha-Oxo-benzeneacetic acid + CoA + NAD+ <=> Benzoyl-CoA + CO2 + NADH + H+
Benzoyl-CoA + Reduced ferredoxin + 2 ATP + 2 H2O <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Oxidized ferredoxin + 2 Orthophosphate + 2 ADP
Benzoyl-CoA + Glycine <=> CoA + Hippurate
Benzoyl-CoA + Anthranilate <=> CoA + N-Benzoylanthranilate
D-Mannonate + NAD+ <=> D-Fructuronate + NADH + H+
D-Mannonate + NAD+ <=> D-Mannuronate + NADH + H+
D-Mannonate + NADP+ <=> D-Mannuronate + NADPH + H+
D-Ornithine + H2O + Oxygen <=> 5-Amino-2-oxopentanoic acid + Ammonia + Hydrogen peroxide
D-Arginine + H2O <=> D-Ornithine + Urea
D-Ornithine + 2-Oxo acid <=> 5-Amino-2-oxopentanoic acid + D-Amino acid
D-Ornithine <=> Bacitracin
D-Ornithine <=> (2R,4S)-2,4-Diaminopentanoate
1-Hexadecanol + NAD+ <=> Hexadecanal + NADH + H+
Hexadecanal + NADP+ <=> Hexadecenal + NADPH + H+
Sphinganine 1-phosphate <=> Ethanolamine phosphate + Hexadecanal
Hyaluronate <=> n 3-(4-Deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine
3-Sulfino-L-alanine <=> Hypotaurine + CO2
Cysteamine + Oxygen <=> Hypotaurine
(S)-Limonene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (-)-trans-Carveol + [Oxidized NADPH---hemoprotein reductase] + H2O
(S)-Limonene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-trans-Isopiperitenol + [Oxidized NADPH---hemoprotein reductase] + H2O
(S)-Limonene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-Perillyl alcohol + [Oxidized NADPH---hemoprotein reductase] + H2O
(R)-Pantoate + NAD+ <=> (R)-4-Dehydropantoate + NADH + H+
(R)-Pantoate + NADP+ <=> 2-Dehydropantoate + NADPH + H+
ATP + (R)-Pantoate + beta-Alanine <=> AMP + Diphosphate + Pantothenate
Pantothenate + H2O <=> (R)-Pantoate + beta-Alanine
Androsterone + NAD+ <=> 5alpha-Androstane-3,17-dione + NADH + H+
Androsterone + NADP+ <=> 5alpha-Androstane-3,17-dione + NADPH + H+
Androsterone + UDP-glucuronate <=> Androsterone glucuronide + UDP
Cytochrome c <=> Apocytochrome c + Heme
Acetyl-CoA + D-Tryptophan <=> CoA + N-Acetyl-D-tryptophan
Malonyl-CoA + D-Tryptophan <=> CoA + N2-Malonyl-D-tryptophan
Deoxyuridine + Orthophosphate <=> Uracil + 2-Deoxy-D-ribose 1-phosphate
Deoxycytidine + H2O <=> Deoxyuridine + Ammonia
Deoxyuridine + 2-Oxoglutarate + Oxygen <=> Deoxyribonolactone + Uracil + Succinate + CO2
Glutaryl-CoA + FAD <=> FADH2 + Crotonoyl-CoA + CO2
Glutaryl-CoA + Electron-transferring flavoprotein <=> Crotonoyl-CoA + Reduced electron-transferring flavoprotein + CO2
2,5-Dihydroxybenzoate <=> Hydroquinone + CO2
Citramalyl-CoA <=> Itaconyl-CoA + H2O
(3S)-Citramalyl-CoA <=> Itaconyl-CoA + H2O
2 Nitric oxide + NADH + H+ <=> Nitrous oxide + NAD+ + H2O
ATP + Pyridoxamine <=> ADP + Pyridoxamine phosphate
Pyridoxamine + Orthophosphate <=> Pyridoxamine phosphate + H2O
Dihydrotestosterone + NADP+ <=> Testosterone + NADPH + H+
5beta-Dihydrotestosterone + NADP+ <=> Testosterone + NADPH + H+
Testosterone + H+ + NADH <=> Androstenediol + NAD+
Testosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Hydroxytestosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Testosterone + UDP-glucuronate <=> Testosterone glucuronide + UDP
Testosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha-Hydroxytestosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Trimetaphosphoric acid + H2O <=> Triphosphate
3 Malonyl-CoA + Cinnamoyl-CoA <=> 4 CoA + Pinosylvin + 4 CO2
Cinnamaldehyde + CoA + NADP+ <=> Cinnamoyl-CoA + NADPH + H+
Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
N,N-Dimethylformamide + H2O <=> Dimethylamine + Formate
Trimethylamine + H2O + Electron-transferring flavoprotein <=> Dimethylamine + Formaldehyde + Reduced electron-transferring flavoprotein
Trimethylamine N-oxide <=> Dimethylamine + Formaldehyde
NG,NG-Dimethyl-L-arginine + H2O <=> Dimethylamine + L-Citrulline
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> Homogentisate + NAD+ + H2O
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> Homogentisate + NAD+ + H2O
4-Hydroxyphenylacetate + Oxygen + NADPH + H+ <=> Homogentisate + NADP+ + H2O
3-Hydroxyphenylacetate + Oxygen + NADPH + H+ <=> Homogentisate + NADP+ + H2O
Homogentisate + Oxygen + NADPH <=> Gentisate aldehyde + CO2 + NADP+ + H+ + H2O
Homogentisate + Oxygen <=> 4-Maleylacetoacetate
Homogentisate + Oxygen <=> Gentisate aldehyde + CO2 + H2O
3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> Homogentisate + CO2
L-Arabinonate <=> 2-Dehydro-3-deoxy-L-arabinonate + H2O
L-Arabinono-1,4-lactone + H2O <=> L-Arabinonate
(R)-Lactaldehyde + NAD+ <=> Methylglyoxal + NADH + H+
Methylglyoxal + NADPH + H+ <=> Hydroxyacetone + NADP+
Aminoacetone + H2O + Oxygen <=> Methylglyoxal + Ammonia + Hydrogen peroxide
(R)-S-Lactoylglutathione <=> Glutathione + Methylglyoxal
Lactaldehyde + NAD+ <=> Methylglyoxal + NADH + H+
L-Noradrenaline + H2O + Oxygen <=> 3,4-Dihydroxymandelaldehyde + Ammonia + Hydrogen peroxide
S-Adenosyl-L-methionine + L-Noradrenaline <=> S-Adenosyl-L-homocysteine + L-Adrenaline
S-Adenosyl-L-methionine + L-Noradrenaline <=> S-Adenosyl-L-homocysteine + L-Normetanephrine
Dopamine + 2 Ascorbate + Oxygen <=> L-Noradrenaline + 2 Monodehydroascorbate + H2O
Phenylacetaldehyde + NAD+ + H2O <=> Phenylacetic acid + NADH + H+
Phenylacetaldehyde + NADP+ + H2O <=> Phenylacetic acid + NADPH + H+
ATP + Phenylacetic acid + CoA <=> AMP + Diphosphate + Phenylacetyl-CoA
2-Phenylacetamide + H2O <=> Phenylacetic acid + Ammonia
Sphingomyelin + H2O <=> N-Acylsphingosine + Choline phosphate
Sphingomyelin + H2O <=> Choline + Ceramide 1-phosphate
Acyl-CoA + Sphingosyl-phosphocholine <=> CoA + Sphingomyelin
meso-Tartaric acid + NAD+ <=> Dihydroxyfumarate + NADH + H+
meso-Tartaric acid + NAD+ <=> 2-Hydroxy-3-oxosuccinate + NADH + H+
(R,R)-Tartaric acid <=> meso-Tartaric acid
trans-2,3-Epoxysuccinate + H2O <=> meso-Tartaric acid
(+)-Neomenthol + NADP+ <=> (-)-Menthone + NADPH + H+
4-Aminobutyraldehyde + NAD+ + H2O <=> 4-Aminobutanoate + NADH + H+
Benzyl alcohol + 2 Oxidized ferredoxin + H2O <=> Toluene + Oxygen + 2 Reduced ferredoxin + 2 H+
N-Benzyloxycarbonylglycine + H2O <=> Benzyl alcohol + CO2 + Glycine
N(alpha)-Benzyloxycarbonyl-L-leucine + H2O <=> Benzyl alcohol + CO2 + L-Leucine
Cyclopentanol + NAD+ <=> Cyclopentanone + NADH + H+
Cyclopentanone + Oxygen + NADPH + H+ <=> 5-Valerolactone + NADP+ + H2O
D-Altronate + NAD+ <=> D-Tagaturonate + NADH + H+
Deoxyadenosine + H2O <=> Deoxyinosine + Ammonia
Deoxyadenosine + Orthophosphate <=> Adenine + 2-Deoxy-D-ribose 1-phosphate
Prunasin + H2O <=> Mandelonitrile + D-Glucose
Trimethylamine + 2 Ferricytochrome c + H2O <=> Trimethylamine N-oxide + 2 Ferrocytochrome c + 2 H+
4-Aminobenzoate + Oxygen + NADH + H+ <=> 4-Hydroxyaniline + CO2 + NAD+ + H2O
4-Aminobenzoate + Oxygen + NADPH + H+ <=> 4-Hydroxyaniline + CO2 + NADP+ + H2O
CDP-ethanolamine + L-Serine <=> CMP + L-Serine-phosphoethanolamine
Cyclohexylsulfamate + H2O <=> Cyclohexylamine + Sulfate
Betaine aldehyde + NAD+ + H2O <=> Betaine + NADH + 2 H+
Betaine aldehyde + NADP+ + H2O <=> Betaine + NADPH + 2 H+
D-Fructose 1-phosphate <=> Glycerone phosphate + D-Glyceraldehyde
Acetyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Succinyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine
Glutaryl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
S-Adenosyl-L-methionine + Dimethyl sulfide <=> S-Adenosyl-L-homocysteine + Trimethylsulfonium
Trimethylsulfonium + Tetrahydrofolate <=> Dimethyl sulfide + 5-Methyltetrahydrofolate
S,S-Dimethyl-beta-propiothetin <=> Dimethyl sulfide + Acrylic acid
ATP + Guanidinoacetate <=> ADP + Phosphoguanidinoacetate
Phenylacetyl-CoA + L-Glutamine <=> CoA + Phenylacetylglutamine
Propane-1,2-diol + NADP+ <=> Lactaldehyde + NADPH + H+
Prostaglandin E2 + NAD+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADH + H+
Prostaglandin F2alpha + NADP+ <=> Prostaglandin E2 + NADPH + H+
Prostaglandin E2 <=> Prostaglandin A2 + H2O
ATP + Protein tyrosine <=> ADP + Protein tyrosine phosphate
Protein tyrosine phosphate + H2O <=> Protein tyrosine + Orthophosphate
3'-Phosphoadenylyl sulfate + Protein tyrosine <=> Adenosine 3',5'-bisphosphate + Protein tyrosine-O-sulfate
2-Deoxy-D-glucose 6-phosphate + H2O <=> 2-Deoxy-D-glucose + Orthophosphate
2-Deoxy-alpha-D-glucoside + H2O <=> Alcohol + 2-Deoxy-D-glucose
3-Hydroxybenzoate + Oxygen + NADH + H+ <=> 2,5-Dihydroxybenzoate + NAD+ + H2O
CTP + N-Trimethyl-2-aminoethylphosphonate <=> Diphosphate + CMP-N-trimethyl-2-aminoethylphosphonate
sn-Glycero-3-phosphocholine + H2O <=> Glycerol + Choline phosphate
N-Dimethyl-2-aminoethylphosphonate + Activated methyl group <=> N-Trimethyl-2-aminoethylphosphonate
Coniferyl alcohol + NADP+ <=> Coniferyl aldehyde + NADPH + H+
UDP-glucose + Coniferyl alcohol <=> UDP + Coniferin
Coniferin + H2O <=> Coniferyl alcohol + D-Glucose
Coniferyl alcohol <=> Guaiacyl lignin
N-Acylneuraminate 9-phosphate + H2O <=> N-Acylneuraminate + Orthophosphate
CMP-N-acylneuraminate + H2O <=> CMP + N-Acylneuraminate
CTP + N-Acylneuraminate <=> Diphosphate + CMP-N-acylneuraminate
Sulfoacetaldehyde + NADPH + H+ <=> 2-Hydroxyethanesulfonate + NADP+
2-Hydroxy-2,4-pentadienoate + H2O <=> 4-Hydroxy-2-oxopentanoate
gamma-Oxalocrotonate <=> 2-Hydroxy-2,4-pentadienoate + CO2
2-Hydroxy-2,4-pentadienoate + Succinate <=> 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O
2-Hydroxy-2,4-pentadienoate + Formate <=> 2-Hydroxymuconate semialdehyde + H2O
2-Amino-4-chloro-4-pentenoic acid + H2O <=> 2-Hydroxy-2,4-pentadienoate + Cl- + Ammonia
2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O <=> Benzoate + 2-Hydroxy-2,4-pentadienoate
5beta-Cholestan-3-one + NADP+ <=> Cholest-4-en-3-one + NADPH + H+
5alpha-Cholestan-3-one + NADP+ <=> Cholest-4-en-3-one + NADPH + H+
Phenylethyl alcohol + NAD+ <=> Phenylacetaldehyde + NADH + H+
Phenethylamine + H2O + Acceptor <=> Phenylacetaldehyde + Ammonia + Reduced acceptor
Phenethylamine + Oxygen + H2O <=> Phenylacetaldehyde + Ammonia + Hydrogen peroxide
Styrene oxide <=> Phenylacetaldehyde
Acetyl-CoA + beta-D-Galactoside <=> CoA + 6-Acetyl-beta-D-galactoside
2,3-Dehydroacyl-CoA + sn-Glycerol 3-phosphate <=> CoA + 1-Acyl-sn-glycerol 3-phosphate
3-Sulfino-L-alanine + NAD+ + H2O <=> 3-Sulfinylpyruvate + Ammonia + NADH + H+
3-Sulfino-L-alanine + 2-Oxoglutarate <=> 3-Sulfinylpyruvate + L-Glutamate
Long-chain aldehyde + CoA + NADP+ <=> Long-chain acyl-CoA + NADPH + H+
Protein-L-arginine + H2O <=> Protein L-citrulline + Ammonia
Protein glutamine + H2O <=> Protein glutamate + Ammonia
S-Adenosyl-L-methionine + Protein glutamate <=> S-Adenosyl-L-homocysteine + Protein glutamate methyl ester
Protein glutamate methyl ester + H2O <=> Protein glutamate + Methanol
ATP + Protein histidine <=> ADP + Protein N(pi)-phospho-L-histidine
ATP + Protein histidine <=> ADP + Protein N(tau)-phospho-L-histidine
S-Adenosyl-L-methionine + Protein histidine <=> S-Adenosyl-L-homocysteine + Protein N(tau)-methyl-L-histidine
Phosphoenolpyruvate + Protein histidine <=> Pyruvate + Protein N(pi)-phospho-L-histidine
Protein N(pi)-phospho-L-histidine + D-Mannose <=> Protein histidine + D-Mannose 6-phosphate
Protein N(pi)-phospho-L-histidine + D-Glucosamine <=> Protein histidine + D-Glucosamine 6-phosphate
3'-Phosphoadenylyl sulfate + Quercetin 3-sulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,3'-bissulfate
3'-Phosphoadenylyl sulfate + Quercetin 3-sulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,4'-bissulfate
UDP-D-galacturonate + Diphosphate <=> 1-Phospho-alpha-D-galacturonate + UTP
UDP-D-galacturonate <=> UDP-L-arabinose + CO2
3-Dehydro-L-gulonate + NAD+ <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + NADH + H+
3-Dehydro-L-gulonate + NADP+ <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + NADPH + H+
L-Gulonate + NAD+ <=> 3-Dehydro-L-gulonate + NADH + H+
3-Oxo-5beta-steroid + Acceptor <=> 3-Oxo-Delta4-steroid + Reduced acceptor
3-Oxo-5alpha-steroid + Acceptor <=> 3-Oxo-Delta4-steroid + Reduced acceptor
3-Oxo-Delta5-steroid <=> 3-Oxo-Delta4-steroid
Urate-3-ribonucleoside + Orthophosphate <=> Urate + alpha-D-Ribose 1-phosphate
Glycerol 1,2-cyclic phosphate + H2O <=> DL-Glycerol 1-phosphate
ATP + N-Acetyl-L-glutamate <=> ADP + N-Acetyl-L-glutamate 5-phosphate
ATP + N-Acyl-D-mannosamine <=> ADP + N-Acyl-D-mannosamine 6-phosphate
N-Acyl-D-mannosamine + NAD+ <=> N-Acyl-D-mannosaminolactone + NADH + H+
N-Acyl-D-glucosamine <=> N-Acyl-D-mannosamine
UDP-N-acetyl-alpha-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + N-Acetyl-D-glucosaminylphosphatidylinositol
Gentisate aldehyde + NAD+ + H2O <=> 2,5-Dihydroxybenzoate + NADH + H+
2,5-Dihydroxybenzoate + Oxygen <=> Maleylpyruvate
2,5-Dihydroxybenzoate + Hydrogen peroxide <=> Gentisate aldehyde + Oxygen + H2O
ATP + 2-Keto-D-gluconic acid <=> ADP + 6-Phospho-2-dehydro-D-gluconate
2-Keto-D-gluconic acid <=> 2-Dehydro-D-glucono-1,5-lactone + H2O
2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor
2-Methylpropanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
2-Methylpropanoyl-CoA <=> Branched chain fatty acid
2-Phospho-D-glycerate + ATP <=> 2,3-Bisphospho-D-glycerate + ADP
3-Hydroxyanthranilate + Oxygen <=> 2-Amino-3-carboxymuconate semialdehyde
3-Hydroxyanthranilate + Oxygen <=> 6-Imino-5-oxocyclohexa-1,3-dienecarboxylate + Hydrogen peroxide
S-Adenosyl-L-methionine + 3-Hydroxyanthranilate <=> S-Adenosyl-L-homocysteine + 3-Hydroxy-4-methylanthranilate
3-Hydroxy-L-kynurenine + H2O <=> 3-Hydroxyanthranilate + L-Alanine
3-Hydroxyanthranilate <=> 2-Aminophenol + CO2
2 3-Hydroxyanthranilate + 4 Oxygen <=> Cinnavalininate + 2 Superoxide + 2 Hydrogen peroxide + 2 H+
3-Hydroxyanthranilate + S-Adenosyl-L-methionine <=> 3-Methoxyanthranilate + S-Adenosyl-L-homocysteine
4-Hydroxyphenylglyoxylate <=> 4-Hydroxybenzaldehyde + CO2
(S)-4-Hydroxymandelate + Oxygen <=> 4-Hydroxybenzaldehyde + Hydrogen peroxide + CO2
4-Cresol + 4 Oxidized azurin + H2O <=> 4-Hydroxybenzaldehyde + 4 Reduced azurin + 4 H+
(S)-4-Hydroxymandelonitrile <=> Hydrogen cyanide + 4-Hydroxybenzaldehyde
ADP-mannose + H2O <=> AMP + D-Mannose 1-phosphate
Indole-3-acetaldehyde + NAD+ + H2O <=> Indole-3-acetate + NADH + H+
Indole-3-ethanol + NAD+ <=> Indole-3-acetaldehyde + NADH + H+
Indole-3-ethanol + NADP+ <=> Indole-3-acetaldehyde + NADPH + H+
Indole-3-acetaldehyde + Oxygen + H2O <=> Indole-3-acetate + Hydrogen peroxide
Long-chain-fatty-acyl ethyl ester + H2O <=> Long-chain fatty acid + Ethanol
Prostaglandin F2alpha + NAD+ <=> 15-Keto-prostaglandin F2alpha + NADH + H+
Prostaglandin F2alpha + NADP+ <=> Prostaglandin D2 + NADPH + H+
(3S)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA + H2O
1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid
1,2-Diacyl-sn-glycerol + H2O <=> 2-Acylglycerol + Fatty acid
UDP-glucose + 1,2-Diacyl-sn-glycerol <=> UDP + 3-D-Glucosyl-1,2-diacylglycerol
UDP-alpha-D-galactose + 1,2-Diacyl-sn-glycerol <=> UDP + 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol
1,2-Diacyl-sn-glycerol + Cholesterol <=> 1-Acylglycerol + Cholesterol ester
1,2-Diacyl-sn-glycerol + Sterol <=> 1-Acylglycerol + Steryl ester
2,3-Dehydroacyl-CoA + 1,2-Diacyl-sn-glycerol <=> CoA + Triacylglycerol
4-Hydroxyphenylacetaldehyde + NAD+ + H2O <=> 4-Hydroxyphenylacetate + NADH + H+
4-Hydroxyphenylacetaldehyde + NADP+ + H2O <=> 4-Hydroxyphenylacetate + NADPH + H+
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
ATP + 4-Hydroxyphenylacetate + CoA <=> AMP + Diphosphate + 4-Hydroxyphenylacetyl-CoA
5-Hydroxy-L-tryptophan + 2-Oxoglutarate <=> 5-Hydroxyindolepyruvate + L-Glutamate
5-Hydroxy-L-tryptophan <=> Serotonin + CO2
5-Hydroxy-L-tryptophan + Oxygen <=> 5-Hydroxy-N-formylkynurenine
D-Mannitol 1-phosphate + NAD+ <=> beta-D-Fructose 6-phosphate + NADH + H+
Protein N(pi)-phospho-L-histidine + Mannitol <=> Protein histidine + D-Mannitol 1-phosphate
ATP + N-Acetyl-D-mannosamine <=> ADP + N-Acetyl-D-mannosamine 6-phosphate
N-Acetyl-D-mannosamine + Orthophosphate <=> N-Acetyl-D-mannosamine 6-phosphate + H2O
N-Acetyl-D-mannosamine + UDP <=> UDP-N-acetyl-D-mannosamine + H2O
4-Hydroxyphenylacetonitrile + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (S)-4-Hydroxymandelonitrile + [Oxidized NADPH---hemoprotein reductase] + H2O
UDP-glucose + 4-Hydroxymandelonitrile <=> UDP + Taxiphyllin
ATP + 4-Methylene-L-glutamate + Ammonia <=> AMP + Diphosphate + 4-Methylene-L-glutamine
4-Methylene-L-glutamine + H2O <=> 4-Methylene-L-glutamate + Ammonia
4-Methylene-L-glutamate <=> 4-Methylene-2-oxoglutarate
D-Arabinono-1,4-lactone + H2O <=> D-Arabinonate
D-Arabinono-1,4-lactone + Oxygen <=> Dehydro-D-arabinono-1,4-lactone + Hydrogen peroxide
UDP-glucose + Poly(ribitol phosphate) <=> UDP + beta-D-Glucosylpoly(ribitol phosphate)
UDP-N-acetyl-alpha-D-glucosamine + Poly(ribitol phosphate) <=> UDP + N-Acetyl-D-glucosaminyl-poly(ribitol phosphate)
ATP + D-Alanine + Poly(ribitol phosphate) <=> AMP + Diphosphate + O-D-Alanyl-poly(ribitol phosphate)
Xanthosine 5'-phosphate + H2O <=> Xanthosine + Orthophosphate
XTP + H2O <=> Xanthosine 5'-phosphate + Diphosphate
D-Glyceraldehyde 3-phosphate + Pyruvate <=> 5-(2-Hydroxyethyl)-4-methylthiazole
L-Serine + Indoleglycerol phosphate <=> L-Tryptophan + D-Glyceraldehyde 3-phosphate + H2O
Cholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 22(R)-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
Cholesterol + 3 Oxygen + 6 H+ + 6 Reduced adrenal ferredoxin <=> 4-Methylpentanal + Pregnenolone + 4 H2O + 6 Oxidized adrenal ferredoxin
2 Reduced adrenal ferredoxin + Androstenedione + Oxygen + 2 H+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + 2 Oxidized adrenal ferredoxin + H2O
2 Reduced adrenal ferredoxin + Steroid + Oxygen + 2 H+ <=> 11beta-Hydroxysteroid + 2 Oxidized adrenal ferredoxin + H2O
alpha,alpha-Trehalose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate
beta-D-Glucose 1-phosphate <=> beta-D-Glucose 6-phosphate
5-Formiminotetrahydrofolate + Glycine <=> Tetrahydrofolate + N-Formiminoglycine
beta-D-Fructose 2,6-bisphosphate + H2O <=> beta-D-Fructose 2-phosphate + Orthophosphate
beta-D-Fructose 2,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate
ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 2,6-bisphosphate
N6-Acetyl-LL-2,6-diaminoheptanedioate + H2O <=> Acetate + LL-2,6-Diaminoheptanedioate
N-Succinyl-LL-2,6-diaminoheptanedioate + H2O <=> Succinate + LL-2,6-Diaminoheptanedioate
LL-2,6-Diaminoheptanedioate <=> meso-2,6-Diaminoheptanedioate
beta-D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+
UDP-glucose + alpha-D-Glucose 6-phosphate <=> UDP + alpha,alpha'-Trehalose 6-phosphate
Protein N(pi)-phospho-L-histidine + D-Glucose <=> Protein histidine + alpha-D-Glucose 6-phosphate
alpha-D-Glucose 6-phosphate <=> beta-D-Glucose 6-phosphate
alpha-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate
ATP + gamma-L-Glutamyl-L-cysteine + beta-Alanine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteinyl-beta-alanine
2 gamma-L-Glutamyl-L-cysteine + NADP+ <=> Bis-gamma-glutamylcystine + NADPH + H+
gamma-L-Glutamyl-L-cysteine <=> 5-Oxoproline + L-Cysteine
sn-Glycero-3-phosphocholine + Carboxylate <=> 2-Acyl-sn-glycero-3-phosphocholine + H2O
1-(1-Alkenyl)-sn-glycero-3-phosphocholine + H2O <=> Aldehyde + sn-Glycero-3-phosphocholine
1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid
2-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid
Deoxyinosine + Orthophosphate <=> Hypoxanthine + 2-Deoxy-D-ribose 1-phosphate
2-Deoxy-D-ribose 1-phosphate <=> 2-Deoxy-D-ribose 5-phosphate
2-Deoxy-D-ribose 5-phosphate + ADP <=> Deoxyribose + ATP
Deoxynucleoside 3'-phosphate + H2O <=> Deoxynucleoside + Orthophosphate
D-Glucarate <=> 5-Dehydro-4-deoxy-D-glucarate + H2O
5-Dehydro-4-deoxy-D-glucarate <=> Pyruvate + 2-Hydroxy-3-oxopropanoate
meso-2,6-Diaminoheptanedioate + NADP+ + H2O <=> L-2-Amino-6-oxoheptanedioate + Ammonia + NADPH + H+
1-Acyl-sn-glycerol 3-phosphate + NADP+ <=> Acylglycerone phosphate + NADPH + H+
ATP + 1-Acylglycerol <=> ADP + 1-Acyl-sn-glycerol 3-phosphate
ATP + 2-Acylglycerol <=> ADP + 2-Acyl-sn-glycerol 3-phosphate
2,3-Dehydroacyl-CoA + 1-Acyl-sn-glycerol 3-phosphate <=> CoA + Phosphatidate
2-Hydroxymuconate semialdehyde + NAD+ + H2O <=> 2-Hydroxymuconate + NADH + H+
2-Hydroxymuconate semialdehyde + CO2 <=> 3-Carboxy-2-hydroxymuconate semialdehyde
(S)-Methylmalonyl-CoA + H2O <=> Methylmalonate + CoA
(R)-Methylmalonyl-CoA <=> (S)-Methylmalonyl-CoA
(3R)-3-Hydroxyacyl-[acyl-carrier protein] + NAD+ <=> 3-Oxoacyl-[acyl-carrier protein] + NADH + H+
(3R)-3-Hydroxyacyl-[acyl-carrier protein] + NADP+ <=> 3-Oxoacyl-[acyl-carrier protein] + NADPH + H+
Acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> 3-Oxoacyl-[acyl-carrier protein] + CO2 + Acyl-carrier protein
N-Acylneuraminate 9-phosphate + Orthophosphate <=> N-Acyl-D-mannosamine 6-phosphate + Phosphoenolpyruvate + H2O
N-Acyl-D-mannosamine 6-phosphate <=> N-Acyl-D-glucosamine 6-phosphate
dTDP-4-acetamido-4,6-dideoxy-D-glucose + 2-Oxoglutarate + CoA <=> dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate + Acetyl-CoA
dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate <=> dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate
dTDP-6-deoxy-beta-L-talose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+
dTDP-L-rhamnose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+
alpha,alpha'-Trehalose 6-phosphate + H2O <=> alpha,alpha-Trehalose + Orthophosphate
alpha,alpha-Trehalose + Protein N(pi)-phospho-L-histidine <=> alpha,alpha'-Trehalose 6-phosphate + Protein histidine
L-Glutamine + 2,4,6/3,5-Pentahydroxycyclohexanone <=> 2-Oxoglutaramate + 1-Amino-1-deoxy-scyllo-inositol
2,4,6/3,5-Pentahydroxycyclohexanone <=> 3D-3,5/4-Trihydroxycyclohexane-1,2-dione + H2O
ATP + UDP-N-acetylmuramoyl-L-alanine + D-Glutamate <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-Lysine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine
ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-2,6-Diaminoheptanedioate <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R
UDP-alpha-D-galactose + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> UDP + alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R
Cholic acid + NAD+ <=> 7-Oxodeoxycholate + NADH + H+
Cholic acid + NADP+ <=> 3alpha,7alpha-Dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
ATP + Cholic acid + CoA <=> AMP + Diphosphate + Choloyl-CoA
Taurocholate + H2O <=> Cholic acid + Taurine
Cholic acid <=> 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + H2O
11-epi-Prostaglandin F2alpha + NADP+ <=> Prostaglandin D2 + H+ + NADPH
Prostaglandin D2 + NADP+ <=> (5Z,13E)-9alpha-Hydroxy-11,15-dioxoprosta-5,13-dienoate + NADPH + H+
Prostaglandin D2 <=> Prostaglandin J2 + H2O
Nitrogen + 2 e- + 2 H+ <=> Diimine
Nitrogen + 2 Ferricytochrome c + H2O <=> Nitrous oxide + 2 Ferrocytochrome c + 2 H+
P1,P4-Bis(5'-xanthosyl) tetraphosphate + H2O <=> XTP + Xanthosine 5'-phosphate
Thymidine + Base <=> Deoxynucleoside + Thymine
Hg + NADP+ + H+ <=> Mercury(2+) + NADPH
S-Adenosyl-L-methionine + Amine <=> S-Adenosyl-L-homocysteine + Methylated amine
3'-Phosphoadenylyl sulfate + Amine <=> Adenosine 3',5'-bisphosphate + Sulfamate
2 Iodide + Hydrogen peroxide + 2 H+ <=> Iodine + 2 H2O
Cyanohydrin <=> Ketone + Cyanide ion
(R)-10-Hydroxystearate <=> (9Z)-Octadecenoic acid + H2O
Oleoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + (9Z)-Octadecenoic acid
Pterin + H2O <=> 2,4-Dihydroxypteridine + Ammonia
Pterin + Oxygen <=> Isoxanthopterin
L-Serine-phosphoethanolamine + H2O <=> L-Serine + Ethanolamine phosphate
Serine <=> Cysteine
Alditol + NAD+ <=> Aldose + NADH + H+
Alditol + NADP+ <=> Aldose + NADPH + H+
Betaine + L-Homocysteine <=> N,N-Dimethylglycine + L-Methionine
Epoxide + H2O <=> Glycol
Alkene + Oxygen + NADH + H+ <=> Epoxide + NAD+ + H2O
Insulin + 2 Glutathione <=> Reduced insulin + Glutathione disulfide
5-Aminopentanoate <=> D-Proline
Aliphatic amide <=> Nitrile + H2O
Aldoxime <=> Nitrile + H2O
Monocarboxylic acid amide <=> Nitrile + H2O
Nitrile + Oxygen + NADPH + H+ <=> Cyanohydrin + NADP+ + H2O
Orcinol + Oxygen + NADH + H+ <=> 2,3,5-Trihydroxytoluene + NAD+ + H2O
Orsellinate <=> Orcinol + CO2
Tropine + NADP+ <=> Tropinone + NADPH + H+
Chitosan + H2O <=> D-Glucosaminide + Chitosan
Cortisol + NAD+ <=> Cortisone + NADH + H+
Cortisol + NADP+ <=> Cortisone + NADPH + H+
Acetyl-CoA + Cortisol <=> CoA + Cortisol 21-acetate
21-Deoxycortisol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cortisol + [Oxidized NADPH---hemoprotein reductase] + H2O
3'-Phosphoadenylyl sulfate + Cortisol <=> Adenosine 3',5'-bisphosphate + Cortisol 21-sulfate
Cortisol + H+ + NADH <=> 11beta,17alpha,21-Trihydroxypregnenolone + NAD+
11beta,17alpha,21-Trihydroxy-5beta-pregnane-3,20-dione + NADP+ <=> Cortisol + NADPH + H+
11-Deoxycortisol + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Cortisol + 2 Oxidized ferredoxin + H2O
Cysteine + Cyanide ion <=> Hydrogen sulfide + 3-Cyano-L-alanine
D-Aldose + NAD+ <=> D-Aldonolactone + NADH + H+
ATP + D-Hexose <=> ADP + D-Hexose 6-phosphate
ITP + D-Hexose <=> IDP + D-Hexose 6-phosphate
dATP + D-Hexose <=> dADP + D-Hexose 6-phosphate
D-Lysine + 2-Oxo acid <=> 6-Amino-2-oxohexanoate + D-Amino acid
D-Lysine <=> (2R,5S)-2,5-Diaminohexanoate
O-Phospho-D-serine + H2O <=> D-Serine + Orthophosphate
D-Serine + Amino acid(Arg-) <=> D-Lombricine + Ornithine
(R)-Acetoin + NAD+ <=> Diacetyl + NADH + H+
(R)-Acetoin + NADP+ <=> Diacetyl + NADPH + H+
Hydrofluoric acid + Glycolate <=> Fluoroacetate + H2O
S-Adenosyl-L-methionine + Macrocin <=> S-Adenosyl-L-homocysteine + Tylosin
S-Adenosyl-L-methionine + Demethylmacrocin <=> S-Adenosyl-L-homocysteine + Macrocin
(R,S)-Nicotine + Acceptor + H2O <=> (S)-6-Hydroxynicotine + Reduced acceptor
Nicotine + CO2 + H+ <=> 1-Methylpyrrolinium + Nicotinate
S-Adenosyl-L-methionine + Pyridine <=> S-Adenosyl-L-homocysteine + N-Methylpyridinium
Thiamine + Pyridine <=> Heteropyrithiamine + 5-(2-Hydroxyethyl)-4-methylthiazole
Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin
ATP + D-Sorbitol <=> ADP + Sorbitol 6-phosphate
Sorbitol 6-phosphate + H2O <=> D-Sorbitol + Orthophosphate
ITP + D-Sorbitol <=> IDP + Sorbitol 6-phosphate
dATP + D-Sorbitol <=> dADP + Sorbitol 6-phosphate
S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + Spermine
Presqualene diphosphate + NADPH + H+ <=> Diphosphate + Squalene + NADP+
Squalene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (S)-2,3-Epoxysqualene + [Oxidized NADPH---hemoprotein reductase] + H2O
Squalene + H2O <=> Tetrahymanol
Squalene <=> Hopanoid
Vanillyl alcohol + Oxygen <=> 4-Hydroxy-3-methoxy-benzaldehyde + Hydrogen peroxide
1-Octanol + NAD+ <=> 1-Octanal + NADH + H+
Octane + 2 Reduced rubredoxin + Oxygen + 2 H+ <=> 1-Octanol + 2 Oxidized rubredoxin + H2O
(S)-Canadine + 2 Oxygen + H+ <=> Berberine + 2 Hydrogen peroxide
S-Adenosyl-L-methionine + Bergaptol <=> S-Adenosyl-L-homocysteine + Bergapten
ATP + Caldesmon <=> ADP + Caldesmon phosphate
Caldesmon phosphate + H2O <=> Caldesmon + Orthophosphate
Cellulose + H2O <=> Cellulose + Cellobiose
Cellodextrin + (n-2) H2O <=> (n-2) D-Glucose + Cellobiose
Cellulose + Orthophosphate <=> Cellulose + D-Glucose 1-phosphate
UDP-glucose + Cellulose <=> UDP + Cellulose
GDP + Cellulose <=> GDP-glucose + Cellulose
4,5alpha-Dihydrocortisone + NADP+ <=> Cortisone + NADPH + H+
17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ <=> Cortisone + NADPH + H+
D-Proline + Oxygen <=> 1-Pyrroline-2-carboxylate + Hydrogen peroxide
D-Proline + L-Glutamine <=> Linatine
D-Iditol + NAD+ <=> D-Sorbose + NADH + H+
UDP-glucose + Naringenin <=> UDP + Naringenin 7-O-beta-D-glucoside
Flavanone <=> 2'-Hydroxychalcone
Sinapoyl-CoA + D-Glucarate <=> CoA + O-Sinapoylglucarate
Phloretin + H2O <=> Phloretate + Phloroglucinol
Retinoate + UDP-glucuronate <=> all-trans-Retinoyl-beta-glucuronide + UDP
ATP + Rhodopsin <=> ADP + Phosphorhodopsin
Rhodopsin <=> 11-cis-Retinal
Rhodopsin + hn <=> Bathorhodopsin
Scytalone + NADP+ <=> 1,3,6,8-Naphthalenetetrol + NADPH + H+
Scytalone <=> 1,3,8-Naphthalenertriol + H2O
Serotonin + H2O + Oxygen <=> 5-Hydroxyindoleacetaldehyde + Ammonia + Hydrogen peroxide
Serotonin + Oxygen <=> Formyl-5-hydroxykynurenamine
S-Adenosyl-L-methionine + Serotonin <=> S-Adenosyl-L-homocysteine + N-Methylserotonin
Acetyl-CoA + Serotonin <=> CoA + N-Acetylserotonin
Serotonin + 5-Methyltetrahydrofolate <=> 5-Methoxytryptamine + Tetrahydrofolate
4-Imidazolone-5-propanoate <=> Urocanate + H2O
Medicarpin + NADP+ + H2O <=> (-)-Vestitone + NADPH + H+
S-Adenosyl-L-methionine + tRNA guanine <=> S-Adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine
ATP + L-Tyrosine + tRNA(Tyr) <=> AMP + Diphosphate + L-Tyrosyl-tRNA(Tyr)
L-Adrenaline + H2O + Oxygen <=> 3,4-Dihydroxymandelaldehyde + Methylamine + Hydrogen peroxide
S-Adenosyl-L-methionine + L-Adrenaline <=> S-Adenosyl-L-homocysteine + L-Metanephrine
CTP + D-Ribitol 5-phosphate <=> Diphosphate + CDP-ribitol
Creatinine + H2O <=> N-Methylhydantoin + Ammonia
D-Arginine + H2O + Oxygen <=> 5-Guanidino-2-oxopentanoate + Ammonia + Hydrogen peroxide
D-Arginine + 2-Oxo acid <=> 5-Guanidino-2-oxopentanoate + D-Amino acid
D-Sorbitol + FAD <=> FADH2 + L-Sorbose
Melibiitol + H2O <=> D-Sorbitol + D-Galactose
ATP + D-Tagatose <=> ADP + D-Tagatose 6-phosphate
Galactitol + NAD+ <=> D-Tagatose + NADH + H+
ATP + L-Glutamate + Ethylamine <=> ADP + Orthophosphate + N5-Ethyl-L-glutamine
N5-Ethyl-L-glutamine + H2O <=> L-Glutamate + Ethylamine
S-Adenosyl-L-methionine + Genistein <=> S-Adenosyl-L-homocysteine + Biochanin A
UDP-glucose + Genistein <=> UDP + Genistein 7-O-beta-D-glucoside
L-Gulono-1,4-lactone + H2O <=> L-Gulonate
Nucleoside 5'-phosphate + Deoxynucleoside <=> Nucleoside + Deoxynucleoside 5'-phosphate
(S)-Ureidoglycolate + NAD+ <=> Oxalureate + NADH + H+
(S)-Ureidoglycolate + NADP+ <=> Oxalureate + NADPH + H+
Carbamoyl phosphate + Oxamate <=> Orthophosphate + Oxalureate
Pentanamide + H2O <=> Pentanoate + Ammonia
2-Propynal + NAD+ + H2O <=> Propynoate + NADH + H+
Salicylaldehyde + NAD+ + H2O <=> Salicylate + NADH + H+
Aspirin + H2O <=> Salicylate + Acetate
Tryptophan + Dimethylallyl diphosphate <=> Dimethylallyltryptophan + Diphosphate
(+)-Borneol + NAD+ <=> (+)-Camphor + NADH + H+
(-)-Borneol + NAD+ <=> (-)-Camphor + NADH + H+
(R,R)-Butane-2,3-diol + NAD+ <=> (R)-Acetoin + NADH + H+
(S)-2-Acetolactate <=> (R)-Acetoin + CO2
(R)-Acetoin <=> (S)-Acetoin
4-Coumarate + Oxygen + Caffeate <=> Caffeate + H2O + Caffeoquinone
UDP-glucose + 4-Coumarate <=> UDP + 4-O-beta-D-Glucosyl-4-hydroxycinnamate
4-Coumarate <=> 4-Hydroxystyrene + CO2
S-Alkyl-L-cysteine + H2O <=> Alkyl thiol + Ammonia + Pyruvate
Dihydrobiochanin A + NADP+ <=> Biochanin A + NADPH + H+
Acetyl-CoA + Citramalate <=> Acetate + (3S)-Citramalyl-CoA
D-Glucuronolactone + NAD+ + 2 H2O <=> D-Glucarate + NADH + H+
D-Glutamine <=> D-Glutamyl-peptide
DNA 4,6-diamino-5-formamidopyrimidine <=> DNA adenine + H2O
S-Adenosyl-L-methionine + DNA adenine <=> S-Adenosyl-L-homocysteine + DNA 6-methylaminopurine
Dopaquinone <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
Lactoyl-CoA <=> Propenoyl-CoA + H2O
Menaquinone + H+ + NADH <=> Menaquinol + NAD+
Menaquinone + Hydrogen <=> Menaquinol
Naphthalene + Oxygen + NADH + H+ <=> cis-1,2-Dihydronaphthalene-1,2-diol + NAD+
Hydroxymalonate + NAD+ <=> Oxomalonate + NADH + H+
Pyruvate + Aminomalonate <=> L-Alanine + Oxomalonate
ATP + Pantetheine <=> ADP + Pantetheine 4'-phosphate
N-((R)-Pantothenoyl)-L-cysteine <=> Pantetheine + CO2
Pantetheine + H2O <=> Pantothenate + Cysteamine
Sepiapterin + H2O <=> Xanthopterin-B2 + Ammonia
7,8-Dihydrobiopterin + NADP+ <=> Sepiapterin + NADPH + H+
ATP + Sphinganine <=> ADP + Sphinganine 1-phosphate
Sphinganine + NADP+ <=> 3-Dehydrosphinganine + NADPH + H+
Sphinganine + FAD <=> FADH2 + Sphingosine
ATP + Tropomyosin <=> ADP + O-Phosphotropomyosin
S-Adenosyl-L-methionine + Xanthotoxol <=> S-Adenosyl-L-homocysteine + Xanthotoxin
dTDP-glucose + 2 NADP+ + H2O <=> dTDP-D-glucuronate + 2 NADPH + 2 H+
dTDP-glucose <=> dTDP-galactose
Prunasin + D-Glucose <=> Amygdalin + H2O
ATP + 2-Furoate + CoA <=> AMP + Diphosphate + 2-Furoyl-CoA
2-Furoyl-CoA + Acceptor + H2O <=> S-(5-Hydroxy-2-furoyl)-CoA + Reduced acceptor
3-Oxoadipate + NAD+ <=> 2-Maleylacetate + NADH + H+
3-Oxoadipate + NADP+ <=> 2-Maleylacetate + NADPH + H+
Succinyl-CoA + 3-Oxoadipate <=> Succinate + 3-Oxoadipyl-CoA
2-Oxo-2,3-dihydrofuran-5-acetate + H2O <=> 3-Oxoadipate
4-Pyridoxolactone + H2O <=> 4-Pyridoxate
4-Pyridoxate + Acceptor <=> 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate + Reduced acceptor
6-endo-Hydroxycineole + NAD+ <=> 6-Oxocineole + NADH + H+
6-Oxocineole + Oxygen + NADPH + H+ <=> 1,6,6-Trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + NADP+ + H2O
Aryl sulfate + Phenol <=> Phenol + Aryl sulfate
Chlorogenate + H2O <=> Caffeate + Quinate
Chlorogenate + D-Glucarate <=> Quinate + 2-O-Caffeoylglucarate
Cyanide ion + Cob(I)alamin + NADP+ <=> Cyanocobalamin + NADPH
D-Methionine + Pyruvate <=> 4-Methylthio-2-oxobutanoic acid + L-Alanine
S-Adenosyl-L-methionine + DNA cytosine <=> S-Adenosyl-L-homocysteine + DNA N4-methylcytosine
Deamino-NAD+ + H2O <=> AMP + Nicotinate D-ribonucleotide
ATP + Nicotinate D-ribonucleotide <=> Diphosphate + Deamino-NAD+
Formononetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Calycosin + [Oxidized NADPH---hemoprotein reductase] + H2O
Gibberellin A1 + 2-Oxoglutarate + Oxygen <=> Gibberellin A8 + Succinate + CO2
Gibberellin A20 + 2-Oxoglutarate + Oxygen <=> Gibberellin A1 + Succinate + CO2
L-Histidinol + NAD+ <=> L-Histidinal + NADH + H+
L-Histidinol phosphate + H2O <=> L-Histidinol + Orthophosphate
ATP + L-Rhamnulose <=> ADP + L-Rhamnulose 1-phosphate
Formylmethanofuran + 2 Oxidized ferredoxin + H2O <=> Methanofuran + 2 Reduced ferredoxin + CO2 + 2 H+
Monoterpenyl diphosphate + H2O <=> Monoterpenol + Diphosphate
Acetyl-CoA + Monoterpenol <=> CoA + Monoterpenol acetate ester
ATP + Pantothenate <=> ADP + D-4'-Phosphopantothenate
S-Adenosyl-L-methionine + tRNA uridine <=> 5'-Methylthioadenosine + 3-[(3S)-3-Amino-3-carboxypropyl]-uridine in tRNA
tRNA uridine <=> tRNA pseudouridine
(R)-2-Hydroxystearate + NAD+ <=> 2-Oxooctadecanoic acid + NADH + H+
(S)-2-Hydroxystearate + NAD+ <=> 2-Oxooctadecanoic acid + NADH + H+
4-Nitrophenol + Oxygen + NADH + H+ <=> 4-Nitrocatechol + NAD+ + H2O
4-Nitrophenyl phosphate + H2O <=> 4-Nitrophenol + Orthophosphate
Coenzyme F420 + Hydrogen <=> Reduced coenzyme F420
(S)-3-Hydroxybutanoyl-CoA <=> Crotonoyl-CoA + H2O
(R)-3-Hydroxybutanoyl-CoA <=> Crotonoyl-CoA + H2O
Glutaconyl-1-CoA <=> Crotonoyl-CoA + CO2
L-3-Aminobutyryl-CoA <=> Crotonoyl-CoA + Ammonia
Vinylacetyl-CoA <=> Crotonoyl-CoA
D-Arabinonate <=> 2-Dehydro-3-deoxy-D-xylonate + H2O
D-Galactonate <=> 2-Dehydro-3-deoxy-D-galactonate + H2O
D-Galactono-1,4-lactone + H2O <=> D-Galactonate
ATP + Pantetheine 4'-phosphate <=> Diphosphate + Dephospho-CoA
Dephospho-CoA + H2O <=> Pantetheine 4'-phosphate + AMP
Isochorismate + H2O <=> (2S,3S)-2,3-Dihydro-2,3-dihydroxybenzoate + Pyruvate
ATP + L-Alanine + tRNA(Ala) <=> AMP + Diphosphate + L-Alanyl-tRNA
L-Alanyl-tRNA + Phosphatidylglycerol <=> tRNA(Ala) + 3-O-L-Alanyl-1-O-phosphatidylglycerol
3-Propylmalate + CoA <=> Pentanoyl-CoA + H2O + Glyoxylate
Polyphosphate(n) + H2O <=> Polyphosphate(n-1) + Orthophosphate
Pregnan-21-ol + NAD+ <=> Pregnan-21-al + NADH + H+
Pregnan-21-al + NADPH + H+ <=> Pregnan-21-ol + NADP+
3-Hydroxypropionyl-CoA <=> Propenoyl-CoA + H2O
beta-Alanyl-CoA <=> Propenoyl-CoA + Ammonia
11-cis-Retinol + NAD+ <=> 11-cis-Retinal + NADH + H+
11-cis-Retinyl palmitate + H2O <=> 11-cis-Retinol + Hexadecanoic acid
2-Acetolactate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + Pyruvate
2-Acetolactate + NADPH + H+ <=> 2,3-Dihydroxy-3-methylbutanoate + NADP+
2-Acetolactate <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid
L-Norleucine + 2-Oxoglutarate <=> 2-Oxohexanoic acid + L-Glutamate
Cinnamaldehyde + NADPH + H+ <=> Cinnamyl alcohol + NADP+
(R)-5,6-Dihydrothymine + H2O <=> (R)-3-Ureidoisobutyrate
Acetyl-CoA + Gentamicin C1a <=> CoA + N2'-Acetylgentamicin C1a
Leukotriene A4 + H2O <=> Leukotriene B4
5(S)-HPETE <=> Leukotriene A4 + H2O
Leukotriene A4 + Glutathione <=> Leukotriene C4
3'-Ribonucleotide + H2O <=> Ribonucleoside + Orthophosphate
Cephalosporin C + H2O <=> Deacetylcephalosporin C + Acetate
Cephalosporin C + 2-Oxoglutarate <=> (7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + D-Glutamate
Cephalosporin C + CoA <=> Deacetylcephalosporin C + Acetyl-CoA
Acetyl-CoA + Chloramphenicol <=> CoA + Chloramphenicol 3-acetate
6-(Hydroxymethyl)-7,8-dihydropterin + 4-Aminobenzoate <=> Dihydropteroate + H2O
6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-Aminobenzoate <=> Diphosphate + Dihydropteroate
2,3-Dimethylmaleate + H2O <=> (2R,3S)-2,3-Dimethylmalate
Methylitaconate <=> 2,3-Dimethylmaleate
2 Ferrocytochrome + Nitrate <=> 2 Ferricytochrome + Nitrite + H2O
S-Adenosyl-L-methionine + Nocardicin E <=> 5'-Methylthioadenosine + Isonocardicin A
Isonocardicin A <=> Nocardicin A
D-Glucose + Sinapine <=> 1-O-Sinapoyl-beta-D-glucose + Choline
Protein N(pi)-phospho-L-histidine + Sugar <=> Protein histidine + Sugar phosphate
UTP + beta-L-Arabinose 1-phosphate <=> Diphosphate + UDP-L-arabinose
UDP-L-arabinofuranose + Arabinan <=> Arabinan + UDP
UDP-L-arabinose <=> Pentosan + UDP
(R)-Propane-1,2-diol + NAD+ <=> (R)-Lactaldehyde + NADH + H+
2-Dehydro-3-deoxy-D-fuconate <=> Pyruvate + (R)-Lactaldehyde
(R)-Lactaldehyde + Glutathione + NAD+ <=> (R)-S-Lactoylglutathione + NADH + H+
2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate <=> 3-Dehydroquinate + Orthophosphate
3-Dehydroquinate <=> 3-Dehydroshikimate + H2O
Estradiol-17beta + Reduced acceptor + Oxygen <=> 6beta-Hydroxy-17beta-estradiol + Acceptor + H2O
19-Oxotestosterone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Estradiol-17beta + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O
Estradiol-17beta + H+ + Oxygen + NADH <=> 2-Hydroxyestradiol + NAD+ + H2O
Estradiol-17beta + H+ + Oxygen + NADPH <=> Estriol + NADP+ + H2O
Estradiol-17beta + H+ + Oxygen + NADPH <=> 2-Hydroxyestradiol + NADP+ + H2O
Estradiol-17beta + UDP-glucuronate <=> Estradiol-17beta 3-glucuronide + UDP
Indole-3-acetate + Oxygen <=> 3-Methyldioxyindole + CO2
3-Indoleacetonitrile + 2 H2O <=> Indole-3-acetate + Ammonia
UDP-glucose + Indole-3-acetate <=> UDP + Indole-3-acetyl-beta-1-D-glucoside
ATP + Indole-3-acetate + L-Lysine <=> ADP + Orthophosphate + N(6)-[(Indol-3-yl)acetyl]-L-lysine
(Indol-3-yl)acetamide + H2O <=> Indole-3-acetate + Ammonia
Indole-3-acetate + Oxygen <=> 2-Formaminobenzoylacetate
L-2-Aminoadipate + ATP <=> L-2-Aminoadipate adenylate + Diphosphate
L-2-Aminoadipate 6-semialdehyde + NAD+ + H2O <=> L-2-Aminoadipate + NADH + H+
L-2-Aminoadipate 6-semialdehyde + NADP+ + H2O <=> L-2-Aminoadipate + NADPH + H+
3-Mercaptolactate + NAD+ <=> Mercaptopyruvate + NADH + H+
Mercaptopyruvate + Thioredoxin <=> Hydrogen sulfide + Pyruvate + Thioredoxin disulfide
Plasmenylcholine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphocholine + Fatty acid
Acyl-CoA + 1-(1-Alkenyl)-sn-glycero-3-phosphocholine <=> CoA + Plasmenylcholine
CDP-choline + 1-Alkenyl-2-acylglycerol <=> CMP + Plasmenylcholine
S-Adenosyl-L-methionine + Sterigmatocystin <=> S-Adenosyl-L-homocysteine + O-Methylsterigmatocystin
S-Adenosyl-L-methionine + 6-Demethylsterigmatocystin <=> S-Adenosyl-L-homocysteine + Sterigmatocystin
(-)-trans-Carveol + NADP+ <=> (-)-Carvone + NADPH + H+
1,3-beta-D-Glucan + H2O <=> 1,3-beta-D-Glucan + alpha-D-Glucose
1,3-beta-D-Glucan + Orthophosphate <=> 1,3-beta-D-Glucan + D-Glucose 1-phosphate
UDP-glucose + 1,3-beta-D-Glucan <=> UDP + 1,3-beta-D-Glucan
Propane-1,3-diol + NAD+ <=> 3-Hydroxypropanal + NADH + H+
Aromatic amino acid + 2-Oxoglutarate <=> Aromatic oxo acid + L-Glutamate
Aromatic amino acid + Glyoxylate <=> Aromatic oxo acid + Glycine
Cyclomaltodextrin + H2O <=> Maltodextrin
cis-3,4-Leucopelargonidin + NADP+ <=> Dihydrokaempferol + NADPH + H+
Dihydrokaempferol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taxifolin + [Oxidized NADPH---hemoprotein reductase] + H2O
Dihydrokaempferol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Dihydromyricetin + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Dihydrokaempferol + 2-Oxoglutarate + Oxygen <=> Kaempferol + Succinate + CO2 + H2O
Dihydroxyfumarate <=> 2-Hydroxy-3-oxopropanoate + CO2
Dihydroxyfumarate <=> 2-Hydroxy-3-oxosuccinate
GDP-D-mannuronate + (Alginate)n <=> GDP + (Alginate)n
S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin
O-Acetyl-L-serine + Uracil <=> 3-(Uracil-1-yl)-L-alanine + Acetate
O-Acetyl-L-serine + Thiosulfate <=> S-Sulfo-L-cysteine + Acetate
O-Acetyl-L-serine + Zeatin <=> Lupinate + Acetate
O-Acetyl-L-serine + Pyrazole <=> 3-(Pyrazol-1-yl)-L-alanine + Acetate
Polyvinyl alcohol + Oxygen <=> Oxidized polyvinyl alcohol + Hydrogen peroxide
Polyvinyl alcohol + Ferricytochrome c <=> Oxidized polyvinyl alcohol + Ferrocytochrome c + H+
Renilla luciferin + Oxygen <=> Oxidized Renilla luciferin + CO2
3'-Phosphoadenylyl sulfate + Renilla luciferin <=> Adenosine 3',5'-bisphosphate + Luciferyl sulfate
1,3-Diaminopropane + Oxygen + H2O <=> 3-Aminopropanal + Ammonia + Hydrogen peroxide
D-Ribulose 1,5-bisphosphate + Oxygen <=> 3-Phospho-D-glycerate + 2-Phosphoglycolate
ADP + alpha-D-Aldose 1-phosphate <=> Orthophosphate + ADP-aldose
NDP + alpha-D-Aldose 1-phosphate <=> Orthophosphate + NDP-aldose
Pyruvate + Ubiquinone + H2O <=> Acetate + Ubiquinol + CO2
Formate + 2 Ferricytochrome b1 <=> CO2 + 2 Ferrocytochrome b1 + 2 H+
Ferricytochrome b5 + Ascorbate <=> Monodehydroascorbate + Ferrocytochrome b5 + H+
Phosphoramidate + D-Hexose <=> Ammonia + alpha-D-Hexose 1-phosphate
Nucleoside triphosphate + alpha-D-Aldose 1-phosphate <=> Diphosphate + NDP-hexose
ATP + Myosin light chain <=> ADP + Myosin light chain phosphate
Myosin light chain phosphate + H2O <=> Myosin light chain + Orthophosphate
Acetyl-CoA + (S)-2-Methylmalate <=> Acetate + (3S)-Citramalyl-CoA
Succinyl-CoA + (S)-2-Methylmalate <=> Succinate + (3S)-Citramalyl-CoA
(R)-Pantolactone + NADP+ <=> Dihydro-4,4-dimethyl-2,3-furandione + NADPH + H+
(R)-Pantolactone + Acceptor <=> Dihydro-4,4-dimethyl-2,3-furandione + Reduced acceptor
3-Hydroxypropionyl-CoA + Orthophosphate + ADP <=> 3-Hydroxypropanoate + CoA + ATP
3-Hydroxypropanoate + CoA <=> 3-Hydroxypropionyl-CoA + H2O
ATP + 6-Deoxy-L-galactose <=> ADP + L-Fucose 1-phosphate
alpha-L-Fucoside + H2O <=> Alcohol + 6-Deoxy-L-galactose
6-Deoxy-L-galactose <=> L-Fuculose
6-Hydroxynicotinate + Reduced ferredoxin <=> 6-Oxo-1,4,5,6-tetrahydronicotinate + Oxidized ferredoxin
Hydroxymethylbilane <=> Uroporphyrinogen III + H2O
Hydroxymethylbilane <=> Uroporphyrinogen I + H2O
Lipid hydroperoxide + 2 Glutathione <=> Lipid + Glutathione disulfide + 2 H2O
Acetyl-CoA + N6-Hydroxy-L-lysine <=> CoA + N6-Acetyl-N6-hydroxy-L-lysine
2-Methylbutanoyl-CoA + Electron-transferring flavoprotein <=> 2-Methylbut-2-enoyl-CoA + Reduced electron-transferring flavoprotein + H+
(S)-3-Methyl-2-oxopentanoic acid + CoA + NAD+ <=> (S)-2-Methylbutanoyl-CoA + CO2 + NADH + H+
(S)-2-Methylbutanoyl-CoA + Acceptor <=> 2-Methylbut-2-enoyl-CoA + Reduced acceptor
(S)-2-Methylbutanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
(S)-2-Methylbutanoyl-CoA <=> Branched chain fatty acid
3beta-Hydroxy-Delta5-steroid + NAD+ <=> 3-Oxo-Delta5-steroid + NADH + H+
4-Guanidinobutanal + NAD+ + H2O <=> 4-Guanidinobutanoate + NADH + H+
5-Guanidino-2-oxopentanoate <=> 4-Guanidinobutanal + CO2
4-Guanidinobutanamide + H2O <=> 4-Guanidinobutanoate + Ammonia
4-Maleylacetoacetate <=> 4-Fumarylacetoacetate
ATP + 7,8-Diaminononanoate + CO2 <=> ADP + Orthophosphate + Dethiobiotin
L-Gulono-1,4-lactone + NADP+ <=> D-Glucuronolactone + NADPH + H+
L-Gulono-1,4-lactone + Oxygen <=> L-xylo-Hexulonolactone + Hydrogen peroxide
2 Monodehydroascorbate + Acceptor <=> 2 Dehydroascorbate + Reduced acceptor
2 Monodehydroascorbate <=> Dehydroascorbate + Ascorbate
ATP + N-Methylhydantoin + 2 H2O <=> ADP + Orthophosphate + N-Carbamoylsarcosine
N-Formimino-L-aspartate + H2O <=> N-Formyl-L-aspartate + Ammonia
Folinic acid + L-Glutamate <=> Tetrahydrofolate + N-Formyl-L-glutamate
UDP-glucose + Polyprenyl phosphate <=> UDP + Polyprenylphosphate-glucose
UDP-N-acetylmuramate + NAD+ <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + NADH + H+
UDP-N-acetylmuramate + NADP+ <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + NADPH + H+
ATP + UDP-N-acetylmuramate + L-Alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanine
2 S-Adenosyl-L-methionine + Uroporphyrinogen III <=> 2 S-Adenosyl-L-homocysteine + Precorrin 2
Uroporphyrinogen III + Acceptor <=> Uroporphyrin III + 6 H+ + Reduced acceptor
Uroporphyrinogen III <=> Coproporphyrinogen III + 4 CO2
(R)-4-Dehydropantoate + NAD+ + H2O <=> (R)-3,3-Dimethylmalate + NADH + H+
(S)-2,3-Epoxysqualene <=> Lanosterol
(S)-2,3-Epoxysqualene <=> Cycloartenol
(S)-2,3-Epoxysqualene <=> Triterpenoid
(S)-6-Hydroxynicotine + H2O + Oxygen <=> 6-Hydroxypseudooxynicotine + Hydrogen peroxide
11beta-Hydroxysteroid + NADP+ <=> 11-Oxosteroid + NADPH + H+
2,5-Dihydroxypyridine + Oxygen + H2O <=> Maleamate + Formate
2-Hydroxypyridine + Reduced acceptor + Oxygen <=> 2,5-Dihydroxypyridine + Acceptor + H2O
3,5-Diiodo-L-tyrosine + 2-Oxoglutarate <=> 3,5-Diiodo-4-hydroxyphenylpyruvate + L-Glutamate
2 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Thyroxine + Dehydroalanine + 2 H2O
ATP + Pimelate + CoA <=> AMP + Diphosphate + 6-Carboxyhexanoyl-CoA
6-Carboxyhexanoyl-CoA + L-Alanine <=> 8-Amino-7-oxononanoate + CoA + CO2
Cyclohexane-1,3-dione + H2O <=> 5-Oxohexanoic acid
3-Hydroxycyclohexanone + Acceptor <=> Cyclohexane-1,3-dione + Reduced acceptor
UDP-glucose + Phenylacetothiohydroximate <=> UDP + Desulfoglucotropeolin
3'-Phosphoadenylyl sulfate + Desulfoglucotropeolin <=> Adenosine 3',5'-bisphosphate + Glucotropaeolin
Formate + 2 Ferricytochrome c-553 <=> CO2 + 2 Ferrocytochrome c-553 + H+
N,6-O-Disulfo-D-glucosamine + H2O <=> N-Sulfo-D-glucosamine + Sulfate
O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate
Procollagen L-proline + 2-Oxoglutarate + Oxygen <=> Procollagen trans-3-hydroxy-L-proline + Succinate + CO2
Procollagen L-proline + 2-Oxoglutarate + Oxygen <=> Procollagen trans-4-hydroxy-L-proline + Succinate + CO2
Coproporphyrinogen III + Oxygen <=> Protoporphyrinogen IX + 2 CO2 + 2 H2O
Protoporphyrinogen IX + 3 Oxygen <=> Protoporphyrin + 3 Hydrogen peroxide
4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 4-Methyl-5-(2-phosphooxyethyl)thiazole <=> Diphosphate + Thiamin monophosphate
(3R)-3-Hydroxyacyl-CoA <=> cis-2,3-Dehydroacyl-CoA + H2O
(S)-3-Hydroxybutanoate + 2-Oxoglutarate <=> Acetoacetate + (R)-2-Hydroxyglutarate
16alpha-Hydroxysteroid + NAD+ <=> 16-Oxosteroid + NADH + H+
16alpha-Hydroxysteroid + NADP+ <=> 16-Oxosteroid + NADPH + H+
16alpha-Hydroxysteroid <=> 16beta-Hydroxysteroid
S-Adenosyl-L-methionine + 11-O-Demethyl-17-O-deacetylvindoline <=> S-Adenosyl-L-homocysteine + Deacetylvindoline
Acetyl-CoA + Deacetylvindoline <=> CoA + Vindoline
S-Adenosyl-L-methionine + 8-Amino-7-oxononanoate <=> S-Adenosyl-4-methylthio-2-oxobutanoate + 7,8-Diaminononanoate
Protein N(pi)-phospho-L-histidine + D-Fructose <=> Protein histidine + D-Fructose 1-phosphate
Sorbitol 6-phosphate + NADP+ <=> Sorbose 1-phosphate + NADPH + H+
D-Tagatose 6-phosphate + ATP <=> D-Tagatose 1,6-bisphosphate + ADP
CTP + D-Tagatose 6-phosphate <=> CDP + D-Tagatose 1,6-bisphosphate
UTP + D-Tagatose 6-phosphate <=> UDP + D-Tagatose 1,6-bisphosphate
ITP + D-Tagatose 6-phosphate <=> IDP + D-Tagatose 1,6-bisphosphate
D-Galactose 6-phosphate <=> D-Tagatose 6-phosphate
ATP + L-Fuculose <=> ADP + L-Fuculose 1-phosphate
L-Histidinol phosphate + 2-Oxoglutarate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + L-Glutamate
L-Ribulose 5-phosphate <=> L-Xylulose 5-phosphate
ATP + (R)-5-Phosphomevalonate <=> ADP + (R)-5-Diphosphomevalonate
1,2,3-Trihydroxybenzene + Oxygen <=> gamma-Oxalocrotonate
Gallate <=> 1,2,3-Trihydroxybenzene + CO2
Ornithine + 2-Oxoglutarate <=> 5-Amino-2-oxopentanoic acid + L-Glutamate
5-Amino-2-oxopentanoic acid <=> 1-Pyrroline-2-carboxylate + H2O
5-Amino-2-oxopentanoic acid + Urea <=> 5-Guanidino-2-oxopentanoate + H2O
7,8-Dihydro-7,8-dihydroxykynurenate + NAD+ <=> 7,8-Dihydroxykynurenate + NADH + H+
7,8-Dihydroxykynurenate + Oxygen <=> 5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate
3-Deoxy-D-manno-octulosonate 8-phosphate + Orthophosphate <=> Phosphoenolpyruvate + D-Arabinose 5-phosphate + H2O
6-Phospho-beta-D-galactoside + H2O <=> Alcohol + D-Galactose 6-phosphate
Lactose 6'-phosphate + H2O <=> beta-D-Glucose + D-Galactose 6-phosphate
L-Galactono-1,4-lactone + Acceptor <=> D-Galacturonolactone + Reduced acceptor
ATP + Nucleoside 5'-phosphate <=> AMP + 5'-Phosphonucleoside 3'-diphosphate
3',5'-Cyclic nucleotide + H2O <=> Nucleoside 5'-phosphate
O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate
(-)-trans-Isopiperitenol + NAD+ <=> (-)-Isopiperitenone + NADH + H+
Corticosterone + 2 Reduced adrenal ferredoxin + Oxygen + 2 H+ <=> 18-Hydroxycorticosterone + 2 Oxidized adrenal ferredoxin + H2O
18-Hydroxycorticosterone + Reduced adrenal ferredoxin + Oxygen <=> Aldosterone + Oxidized adrenal ferredoxin + 2 H2O
(2E,6E)-Farnesol + NADP+ <=> 2-trans,6-trans-Farnesal + NADPH + H+
(2E,6E)-Farnesol <=> (2Z,6E)-Farnesol
4-Hydroxy-L-glutamate + 2-Oxoglutarate <=> 4-Hydroxy-2-oxoglutarate + L-Glutamate
UDP-glucose + Flavonol <=> UDP + Flavonol 3-O-beta-D-glucoside
UDP-D-xylose + Flavonol 3-O-D-glycoside <=> UDP + Flavonol 3-O-D-xylosylglycoside
(R)-4'-Phosphopantothenoyl-L-cysteine <=> Pantetheine 4'-phosphate + CO2
2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate
S-Adenosylmethioninamine + 1,3-Diaminopropane <=> 5'-Methylthioadenosine + Norspermidine + H+
ATP + [Acetyl-CoA carboxylase] <=> ADP + [Acetyl-CoA carboxylase] phosphate
[Acetyl-CoA carboxylase] phosphate + H2O <=> [Acetyl-CoA carboxylase] + Orthophosphate
ATP + beta-Adrenergic receptor <=> ADP + Phospho-beta-adrenergic receptor
(3S)-3,6-Diaminohexanoate <=> (3S,5S)-3,5-Diaminohexanoate
(S)-3-Hydroxybutanoyl-CoA <=> (R)-3-Hydroxybutanoyl-CoA
2-Hydroxy-3-oxopropanoate + Pyruvate <=> 2-Dehydro-3-deoxy-D-glucarate
2-Hydroxycyclohexan-1-one + NAD+ <=> Cyclohexane-1,2-dione + NADH + H+
trans-1,2-Cyclohexanediol + NAD+ <=> 2-Hydroxycyclohexan-1-one + NADH + H+
2-Hydroxycyclohexan-1-one + Oxygen + NADPH + H+ <=> 6-Hydroxyhexan-6-olide + NADP+ + H2O
4-Trimethylammoniobutanal + NAD+ + H2O <=> 4-Trimethylammoniobutanoate + NADH + H+
4-Trimethylammoniobutanal + Glycine <=> (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
ATP + N(pi)-Methyl-L-histidine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-N(pi)-methyl-L-histidine
beta-Alanyl-N(pi)-methyl-L-histidine + H2O <=> beta-Alanine + N(pi)-Methyl-L-histidine
3'-Phosphoadenylyl sulfate + Quercetin 3,3'-bissulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,3',7-trissulfate
Hydroxyproline + NAD+ <=> 4-Oxoproline + NADH + H+
Hydroxyproline + NAD+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADH + H+
Hydroxyproline + NADP+ <=> 4-Oxoproline + NADPH + H+
Hydroxyproline + NADP+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADPH + H+
Hydroxyproline + Quinone <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + Hydroquinone
Hydroxyproline <=> cis-4-Hydroxy-D-proline
UDP-glucose + Gallate <=> UDP + 1-O-Galloyl-beta-D-glucose
2,3-Bisphospho-D-glycerate + ATP <=> Cyclic 2,3-bisphospho-D-glycerate + ADP + Orthophosphate
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
3,4-Dihydroxyphenylacetaldehyde + NAD+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADH + H+
3,4-Dihydroxyphenylacetaldehyde + NADP+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADPH + H+
3,4-Dihydroxyphenylacetate + Oxygen <=> 2-Hydroxy-5-carboxymethylmuconate semialdehyde
S-Adenosyl-L-methionine + 3,4-Dihydroxyphenylacetate <=> S-Adenosyl-L-homocysteine + Homovanillate
4-Chlorophenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + Hydrochloric acid + NAD+
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Carboxy-cis,cis-muconate
3-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Carboxy-cis,cis-muconate
7-Dehydrocholesterol + hn <=> Vitamin D3
L-Glutamate 5-semialdehyde + Orthophosphate + NADP+ <=> L-Glutamyl 5-phosphate + NADPH + H+
L-Glutamate 5-semialdehyde <=> (S)-1-Pyrroline-5-carboxylate + H2O
ATP + Pseudouridine <=> ADP + Pseudouridine 5'-phosphate
3-Carboxy-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + Thiamin diphosphate
UDP-N-acetyl-D-mannosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-D-mannosaminouronate + 2 NADH + 2 H+
GTP + alpha-D-Hexose 1-phosphate <=> Diphosphate + GDPhexose
alpha-D-Hexose 1-phosphate <=> alpha-D-Hexose 6-phosphate
beta-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate
Vermelone + NADP+ <=> 1,3,8-Naphthalenertriol + NADPH + H+
1-O-Sinapoyl-beta-D-glucose + (S)-Malate <=> D-Glucose + Sinapoyl malate
17alpha,20alpha-Dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+
17alpha-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycortisol + [Oxidized NADPH---hemoprotein reductase] + H2O
17alpha-Hydroxypregnenolone + NAD+ <=> 17alpha-Hydroxyprogesterone + NADH + H+
17alpha-Hydroxyprogesterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 21-Deoxycortisol + 2 Oxidized ferredoxin + H2O
D-myo-Inositol 1,3-bisphosphate + H2O <=> Inositol 1-phosphate + Orthophosphate
sn-Glycero-3-phospho-1-inositol + H2O <=> Glycerol + Inositol 1-phosphate
1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol
D-myo-Inositol 1,2-cyclic phosphate + H2O <=> Inositol 1-phosphate
2-Acyl-sn-glycero-3-phosphocholine <=> 1-Acyl-sn-glycero-3-phosphocholine
(R)-3-(4-Hydroxyphenyl)lactate + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + NADH + H+
(R)-3-(4-Hydroxyphenyl)lactate + NADP+ <=> 3-(4-Hydroxyphenyl)pyruvate + NADPH + H+
3-(4-Hydroxyphenyl)pyruvate <=> 4-Hydroxyphenylacetaldehyde + CO2
3-(4-Hydroxyphenyl)pyruvate <=> 2-Hydroxy-3-(4-hydroxyphenyl)propenoate
N,N-Dimethylaniline + Oxygen + NADPH + H+ <=> N,N-Dimethylaniline N-oxide + NADP+ + H2O
N,N-Dimethylaniline N-oxide <=> N-Methylaniline + Formaldehyde
Nicotinate D-ribonucleotide + H2O <=> Nicotinate D-ribonucleoside + Orthophosphate
Nicotinate D-ribonucleotide + ADP <=> Nicotinate D-ribonucleoside + ATP
Nicotinate D-ribonucleotide + Diphosphate + CO2 <=> Quinolinate + 5-Phospho-alpha-D-ribose 1-diphosphate
(3S,5S)-3,5-Diaminohexanoate + H2O + NAD+ <=> (S)-5-Amino-3-oxohexanoic acid + Ammonia + NADH + H+
3-Deoxy-D-manno-octulosonate 8-phosphate + H2O <=> 3-Deoxy-D-manno-octulosonate + Orthophosphate
CTP + 3-Deoxy-D-manno-octulosonate <=> Diphosphate + CMP-3-deoxy-D-manno-octulosonate
3-Hydroxy-2-methylpropanoyl-CoA + H2O <=> 3-Hydroxy-2-methylpropanoate + CoA
Lathosterol <=> 5alpha-Cholest-8-en-3beta-ol
Glucosylceramide + UDP-alpha-D-galactose <=> Lactosylceramide + UDP
Lactosylceramide + H2O <=> Glucosylceramide + D-Galactose
Dolichyl D-xylosyl phosphate + [Protein]-L-serine <=> Dolichyl phosphate + D-Xylosylprotein
1-Palmitoylglycerol 3-phosphate + NADP+ <=> Palmitoylglycerone phosphate + NADPH + H+
Octopamine <=> 4-Hydroxyphenylacetaldehyde + Ammonia
(-)-Sympatol <=> 4-Hydroxyphenylacetaldehyde + Methylamine
1-Phosphatidyl-D-myo-inositol + H2O <=> 1-Acylglycerophosphoinositol + Carboxylate
ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate
ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate
1-Phosphatidyl-1D-myo-inositol 3-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate
1-Phosphatidyl-D-myo-inositol <=> D-myo-Inositol 1,2-cyclic phosphate + 1,2-Diacyl-sn-glycerol
Caffeate + Oxygen <=> 3-(2-Carboxyethenyl)-cis,cis-muconate
S-Adenosyl-L-methionine + Caffeate <=> S-Adenosyl-L-homocysteine + Ferulate
Caffeate <=> 3,4-Dihydroxystyrene + CO2
3-(2-Hydroxyphenyl)propanoate + Oxygen + NADH + H+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + NAD+ + H2O
Octadecanoyl-[acyl-carrier protein] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Oleoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O
Phytic acid + H2O <=> D-myo-Inositol 1,2,4,5,6-pentakisphosphate + Orthophosphate
Phytic acid + H2O <=> Inositol 1,2,3,5,6-pentakisphosphate + Orthophosphate
(R)-3-(3,4-Dihydroxyphenyl)lactate + NAD+ <=> 3-(3,4-Dihydroxyphenyl)pyruvate + NADH + H+
Caffeoyl-CoA + (R)-3-(3,4-Dihydroxyphenyl)lactate <=> CoA + Rosmarinate
CTP + N-Methylethanolamine phosphate <=> Diphosphate + CDP-N-methylethanolamine
Protein lysine + 2-Oxoglutarate + Oxygen <=> Procollagen 5-hydroxy-L-lysine + Succinate + CO2
GTP + L-Hydroxylysine <=> GDP + 5-Phosphooxy-L-lysine
UDP-alpha-D-galactose + Procollagen 5-hydroxy-L-lysine <=> UDP + 5-(D-Galactosyloxy)-L-lysine-procollagen
(S)-Methylmalonate semialdehyde + CoA + NAD+ <=> (R)-Methylmalonyl-CoA + NADH + H+
Methylmalonate + CoA + ATP <=> (R)-Methylmalonyl-CoA + AMP + Diphosphate
ATP + 1-Amino-1-deoxy-scyllo-inositol <=> ADP + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate
3-Hydroxy-2-methylpyridine-5-carboxylate + Oxygen + NADH + H+ <=> 2-(Acetamidomethylene)succinate + NAD+
3-Hydroxy-2-methylpyridine-5-carboxylate + Oxygen + NADPH + H+ <=> 2-(Acetamidomethylene)succinate + NADP+
ATP + 2-Dehydro-3-deoxy-D-galactonate <=> ADP + 2-Dehydro-3-deoxy-6-phospho-D-galactonate
5,6,7,8-Tetrahydromethanopterin + NADP+ <=> 7,8-Dihydromethanopterin + H+ + NADPH
Formylmethanofuran + 5,6,7,8-Tetrahydromethanopterin <=> Methanofuran + 5-Formyl-5,6,7,8-tetrahydromethanopterin
CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+
CDP-4-dehydro-3,6-dideoxy-D-glucose + NADP+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+
1D-myo-Inositol 1,4-bisphosphate + H2O <=> myo-Inositol 4-phosphate + Orthophosphate
D-myo-Inositol 1,4,5-trisphosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + Orthophosphate
ATP + Dihydrostreptomycin 6-phosphate <=> ADP + Dihydrostreptomycin 3'alpha,6-bisphosphate
GDP-6-deoxy-D-talose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+
GDP-6-deoxy-D-mannose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+
GDP-6-deoxy-D-talose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
GDP-6-deoxy-D-mannose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
8-[(1R,2R)-3-Oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate + NADP+ <=> 12-OPDA + NADPH + H+
(9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid <=> 12-OPDA
Dehydroepiandrosterone sulfate + H2O <=> Dehydroepiandrosterone + Sulfate
3'-Phosphoadenylyl sulfate + Dehydroepiandrosterone <=> Adenosine 3',5'-bisphosphate + Dehydroepiandrosterone sulfate
Androstenediol + NAD+ <=> Dehydroepiandrosterone + NADH + H+
Androstenediol + NADP+ <=> Dehydroepiandrosterone + NADPH + H+
Dehydroepiandrosterone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxydehydroepiandrosterone + NADP+ + H2O
Guanosine 3'-diphosphate 5'-triphosphate + H2O <=> Guanosine 3',5'-bis(diphosphate) + Orthophosphate
S-Adenosyl-L-methionine + Phospholipid olefinic fatty acid <=> S-Adenosyl-L-homocysteine + Phospholipid methylene fatty acid
S-Adenosyl-L-methionine + Phospholipid olefinic fatty acid <=> S-Adenosyl-L-homocysteine + Phospholipid cyclopropane fatty acid
1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> Aldehyde + sn-Glycero-3-phosphoethanolamine
1-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine
2-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine
alpha-D-Galactosyl-(1->3)-1D-myo-inositol + Raffinose <=> myo-Inositol + Stachyose
N4-(Acetyl-beta-D-glucosaminyl)asparagine + H2O <=> N-Acetyl-beta-D-glucosaminylamine + L-Aspartate
2',3'-Cyclic nucleotide + H2O <=> Nucleoside 2'-phosphate
2',3'-Cyclic nucleotide + H2O <=> Nucleoside 3'-phosphate
S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine
Glycine + Lipoylprotein <=> [Protein]-S8-aminomethyldihydrolipoyllysine + CO2
1D-myo-Inositol 1,3,4-trisphosphate + H2O <=> D-myo-Inositol 3,4-bisphosphate + Orthophosphate
ATP + 1D-myo-Inositol 1,3,4-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate
ATP + 1D-myo-Inositol 1,3,4-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,6-tetrakisphosphate
1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O <=> 1D-myo-Inositol 1,3,4-trisphosphate + Orthophosphate
3-(3,5-Diiodo-4-hydroxyphenyl)lactate + NAD+ <=> 3,5-Diiodo-4-hydroxyphenylpyruvate + NADH + H+
ATP + D-myo-Inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate
1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + Orthophosphate
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol
Acetyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine
Acyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 1-Radyl-2-acyl-sn-glycero-3-phosphocholine
4-Hydroxy-2-quinolinecarboxylic acid + Oxygen + NADH + H+ <=> 7,8-Dihydro-7,8-dihydroxykynurenate + NAD+
4-Hydroxy-2-quinolinecarboxylic acid + Oxygen + NADPH + H+ <=> 7,8-Dihydro-7,8-dihydroxykynurenate + NADP+
4-Hydroxy-2-quinolinecarboxylic acid + Reduced acceptor + Oxygen <=> 7,8-Dihydro-7,8-dihydroxykynurenate + Acceptor
N-Acetyl-L-glutamate 5-semialdehyde + Orthophosphate + NADP+ <=> N-Acetyl-L-glutamate 5-phosphate + NADPH + H+
(R)-2-Hydroxybutane-1,2,4-tricarboxylate <=> (Z)-But-1-ene-1,2,4-tricarboxylate + H2O
4-(2-Aminophenyl)-2,4-dioxobutanoate <=> 4-Hydroxy-2-quinolinecarboxylic acid + H2O
ADP-D-ribosyl-[dinitrogen reductase] + H2O <=> [Dinitrogen reductase] + ADP-ribose
NAD+ + [Dinitrogen reductase] <=> Nicotinamide + ADP-D-ribosyl-[dinitrogen reductase]
1,8-Diazacyclotetradecane-2,9-dione + H2O <=> N-(6-Aminohexanoyl)-6-aminohexanoate
ATP + [Pyruvate dehydrogenase (acetyl-transferring)] <=> ADP + [Pyruvate dehydrogenase (acetyl-transferring)] phosphate
[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H2O <=> [Pyruvate dehydrogenase (acetyl-transferring)] + Orthophosphate
N6,N6,N6-Trimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinate + CO2
3,9-Dihydroxypterocarpan + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3,6,9-Trihydroxypterocarpan + [Oxidized NADPH---hemoprotein reductase] + H2O
2-Acetyl-1-alkyl-sn-glycero-3-phosphate + H2O <=> 1-Alkyl-2-acetyl-sn-glycerol + Orthophosphate
Acetyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphate
S-Adenosyl-L-methionine + 3,7-Di-O-methylquercetin <=> S-Adenosyl-L-homocysteine + 3,7,4'-Tri-O-methylquercetin
D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + H2O
5-Amino-6-(5'-phospho-D-ribitylamino)uracil + NADP+ <=> 5-Amino-6-(5'-phosphoribosylamino)uracil + NADPH + H+
2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O <=> 5-Amino-6-(5'-phosphoribosylamino)uracil + Ammonia
Phosphoenolpyruvate + Shikimate 3-phosphate <=> Orthophosphate + 5-O-(1-Carboxyvinyl)-3-phosphoshikimate
3-Hydroxy-2-methylpyridine-4,5-dicarboxylate <=> 3-Hydroxy-2-methylpyridine-5-carboxylate + CO2
Biphenyl-2,3-diol + Oxygen <=> 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
2,6-Dioxo-6-phenylhexanoate + NADP+ <=> 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + NADPH + H+
5,10-Methenyltetrahydromethanopterin + H2O <=> 5-Formyl-5,6,7,8-tetrahydromethanopterin + H+
(3E)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate + H2O <=> 2-Carboxybenzaldehyde + Pyruvate
1-Hydroxy-2-naphthoate + Oxygen <=> (3E)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate
1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O <=> 3-beta-D-Galactosyl-sn-glycerol + 2 Carboxylate
CMP-N-acetylneuraminate + 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> CMP + 1,2-Diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol
ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate + CO2
ATP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine <=> ADP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine
Aminoimidazole ribotide + S-Adenosyl-L-methionine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO
ATP + [L-Glutamate:ammonia ligase (ADP-forming)] <=> Diphosphate + Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]
Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + Orthophosphate <=> ADP + [L-Glutamate:ammonia ligase (ADP-forming)]
1-Acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD+ <=> 1-Acyl-2-linoleoyl-sn-glycero-3-phosphocholine + NADH + H+
1-Acyl-2-oleoyl-sn-glycero-3-phosphocholine + Oxygen + NADH + H+ <=> 1-Acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + NAD+ + H2O
L-Arginine + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate <=> L-Ornithine + 1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate
ATP + 1D-myo-Inositol 1,3,4,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
ATP + 1D-myo-Inositol 3,4,5,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
N-Acetyl-D-glucosaminylphosphatidylinositol + H2O <=> 6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol + Acetate
UDP-alpha-D-galactose + Lactosylceramide <=> UDP + alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + GM3
CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide
UDP-N-acetyl-D-galactosamine + Lactosylceramide <=> UDP + GA2
Lactosylceramide + N-Acetylneuraminate <=> GM3 + H2O
GA2 + H2O <=> Lactosylceramide + N-Acetyl-D-galactosamine
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O
ATP + Geranoyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA
3alpha,7alpha,12beta-Trihydroxy-5beta-cholanate + NADP+ <=> 3alpha,7alpha-Dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O <=> 1-Guanidino-1-deoxy-scyllo-inositol + Orthophosphate
5-O-Methyl-myo-inositol + NAD+ <=> 2D-5-O-Methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+
D-Pinitol + NADP+ <=> 2D-5-O-Methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH + H+
1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol + Pyruvate <=> 1D-1-Guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-Alanine
ATP + 6-(Hydroxymethyl)-7,8-dihydropterin <=> AMP + 6-Hydroxymethyl-7,8-dihydropterin diphosphate
7,8-Dihydroneopterin <=> Glycolaldehyde + 6-(Hydroxymethyl)-7,8-dihydropterin
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + NAD+ + H2O <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + NADH + H+
3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 Oxidized adrenal ferredoxin
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate <=> Indoleglycerol phosphate + CO2 + H2O
N-(5-Phospho-D-ribosyl)anthranilate <=> 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
Phylloquinone + Reduced acceptor + Oxygen <=> Vitamin K1 epoxide + Acceptor + H2O
Phylloquinone + Oxidized dithiothreitol + H2O <=> Vitamin K1 epoxide + Dithiothreitol
3-Hydroxy-vitamin K + Oxidized dithiothreitol <=> Vitamin K1 epoxide + Dithiothreitol
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-alpha-D-galactosaminyl-polypeptide <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl-R
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->6)-[N-acetyl-beta-D-glucosaminyl-(1->3)]-N-acetyl-alpha-D-galactosaminyl-R
[3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate + H2O <=> [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] + Orthophosphate
ATP + [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] <=> ADP + [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate
4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate + H2O <=> 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + Sulfate
4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + Sulfate
GDP-L-fucose + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> GDP + beta-D-Galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-D-glucosaminyl-R
Prostaglandin I2 + NADP+ <=> (5Z,13E)-6,9alpha-Epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate + NADPH + H+
Prostaglandin I2 + H2O <=> 6-Keto-prostaglandin F1alpha
RX + Glutathione <=> Halide + R-S-Glutathione
Bromochloromethane + H2O <=> Formaldehyde + Bromide + Cl- + 2 H+
L-Cysteine + Hydrogen cyanide <=> Hydrogen sulfide + 3-Cyano-L-alanine
UDP-glucose + ROH <=> UDP + beta-D-Glucoside
beta-D-Glucoside + H2O <=> D-Glucose + ROH
L-Cysteine-S-conjugate + H2O <=> Aryl thiol + Ammonia + Pyruvate
Alkylmercury + H+ <=> Alkane + Mercury(2+)
ATP + dIDP <=> ADP + dITP
dITP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Diphosphate
Reduced acceptor + Hydrogen peroxide <=> Acceptor + 2 H2O
Sulfur + Reduced acceptor <=> Hydrogen sulfide + Acceptor
2-Hydroxyglutarate + FAD <=> 2-Oxoglutarate + FADH2
PQQH2 + Propynoate <=> 2-Propynal + PQQ + H2O
2',3'-Cyclic AMP + H2O <=> 3'-AMP
2',3'-Cyclic UMP + H2O <=> 3'-UMP
Hydroiodic acid + 3-Iodo-L-tyrosine <=> Iodine + L-Tyrosine
Maleic acid + Ammonia <=> Maleamate + H2O
Prenyl diphosphate + H2O <=> Prenol + Diphosphate
alpha-Aminopropiononitrile + 2 H2O <=> Alanine + Ammonia
Benzene + Oxygen + NADH + H+ <=> cis-1,2-Dihydrobenzene-1,2-diol + NAD+
Butanal + NADH + H+ <=> 1-Butanol + NAD+
Butanal + NADPH + H+ <=> 1-Butanol + NADP+
Cyanate + H+ + HCO3- <=> CO2 + Carbamate
UDP-glucose + Methylazoxymethanol <=> UDP + Cycasin
UDP-glucose + 7,8-Dihydroxycoumarin <=> UDP + Daphnin
Gallate + Oxygen <=> 2-Pyrone-4,6-dicarboxylate + H2O
Gallate + Oxygen <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
Gallate + Methanol <=> 3-O-Methylgallate + H2O
Acetyl-CoA + Histone-L-lysine <=> CoA + Histone N6-acetyl-L-lysine
3'-Phosphoadenylyl sulfate + Keratan sulfate <=> Adenosine 3',5'-bisphosphate + Keratan sulfate
S-Adenosyl-L-methionine + Loganate <=> S-Adenosyl-L-homocysteine + Loganin
Loganin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Secologanin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Deoxyloganin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Loganin + [Oxidized NADPH---hemoprotein reductase] + H2O
Secondary alcohol + NADP+ <=> Ketone + NADPH + H+
UDP-glucose + Salicyl alcohol <=> UDP + Salicin
Toluene + Oxygen + NADH + H+ <=> Toluene-cis-dihydrodiol + NAD+
Toluene + Oxygen + NADH + H+ <=> o-Cresol + NAD+ + H2O
Toluene + Oxygen + NADPH + H+ <=> 3-Cresol + NADP+ + H2O
Atropine + H2O <=> Tropine + Tropate
Tropate + Tropine <=> L-Hyoscyamine + H2O
UDP-glucose + Vitexin <=> Vitexin 2''-O-beta-D-glucoside + UDP
3-Cresol + Oxygen + NADPH + H+ <=> 2,3-Dihydroxytoluene + NADP+ + H2O
6-Methylsalicylate <=> 3-Cresol + CO2
4-Cresol + Oxygen + NADPH + H+ <=> 4-Methylcatechol + NADP+ + H2O
ADP-sugar + H2O <=> AMP + alpha-D-Aldose 1-phosphate
S-Adenosyl-L-methionine + Apigenin <=> S-Adenosyl-L-homocysteine + Acacetin
Allyl alcohol + NADP+ <=> Acrolein + NADPH + H+
UDP-glucose + Alizarin <=> UDP + 1-Hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone
UDP-glucose + Apigenin <=> UDP + Apigenin 7-O-beta-D-glucoside
Chloric acid + Reduced acceptor <=> Chlorous acid + Acceptor + H2O
ATP + D-Allose <=> ADP + D-Allose 6-phosphate
D-Apiitol + NAD+ <=> D-Apiose + NADH + H+
N-Feruloylglycine + H2O <=> Ferulate + Glycine
Geraniol + NADP+ <=> Geranial + NADPH + H+
Indan-1-ol + NAD+ <=> Indanone + NADH + H+
Indan-1-ol + NADP+ <=> Indanone + NADPH + H+
L-Glycol + NAD+ <=> 2-Hydroxycarbonyl compound + NADH + H+
L-Glycol + NADP+ <=> 2-Hydroxycarbonyl compound + NADPH + H+
L-Xylose + NADP+ <=> L-Xylono-1,4-lactone + NADPH + H+
S-Adenosyl-L-methionine + Luteolin <=> S-Adenosyl-L-homocysteine + Chrysoeriol
UDP-glucose + Luteolin <=> UDP + Luteolin 7-O-beta-D-glucoside
UDP-glucuronate + Luteolin <=> UDP + Luteolin 7-O-glucuronide
Eriodictyol + 2-Oxoglutarate + Oxygen <=> Luteolin + Succinate + CO2 + H2O
Morphine + NAD+ <=> Morphinone + NADH + H+
Morphine + NADP+ <=> Morphinone + NADPH + H+
Ricinine + 2 H2O <=> 3-Carboxy-4-methoxy-N-methyl-2-pyridone + Ammonia
UDP-glucose + Scopoletin <=> UDP + Scopolin
ATP + Hydrogen selenide + H2O <=> AMP + Selenophosphoric acid + Orthophosphate
Hydrogen selenide + 3 NADP+ + 3 H2O <=> Selenite + 3 NADPH + 5 H+
Hydrogen selenide + 3 Acceptor + 3 H2O <=> Selenite + 3 Reduced acceptor + 2 H+
L-Selenocysteine + Reduced acceptor <=> Hydrogen selenide + L-Alanine + Acceptor
Hydrogen selenide + 6 Oxidized ferredoxin + 3 H2O <=> Selenite + 6 Reduced ferredoxin + 8 H+
O-Acetyl-L-serine + Hydrogen selenide <=> L-Selenocysteine + Acetate
Selenium <=> Selenite
Selenium <=> Selenate
Syringin + H2O <=> Sinapyl alcohol + D-Glucose
UDP-glucose + Sinapyl alcohol <=> UDP + Syringin
ATP + Viomycin <=> ADP + O-Phosphoviomycin
o-Cresol + Oxygen + NADH + H+ <=> 2,3-Dihydroxytoluene + NAD+ + H2O
Agaritine + Acceptor <=> 4-Hydroxymethylphenylhydrazine + gamma-L-Glutamyl-acceptor
Calcidiol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitriol + Oxidized adrenal ferredoxin + H2O
Calcidiol + [Oxidized NADPH---hemoprotein reductase] + H2O <=> Vitamin D3 + [Reduced NADPH---hemoprotein reductase] + Oxygen
Cetraxate benzyl ester + H2O <=> Cetraxate + Benzyl alcohol
ATP + Peptide diphthine + Ammonia + H+ <=> AMP + Diphosphate + Peptide diphthamide
Ephedrine + NAD+ <=> (R)-2-Methylimino-1-phenylpropan-1-ol + NADH + H+
Flavonoid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3'-Hydroxyflavonoid + [Oxidized NADPH---hemoprotein reductase] + H2O
3-beta-D-Galactosyl-sn-glycerol + H2O <=> Galactose + Glycerol
Galactosylceramide + H2O <=> D-Galactose + N-Acylsphingosine
alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O <=> D-Galactose + Lactosylceramide
N-Methylhexanamide + H2O <=> Hexanoic acid + Methylamine
Acetyl-CoA + Imidazole <=> CoA + N-Acetylimidazole
Kievitone hydrate <=> Kievitone + H2O
S-Adenosyl-L-methionine + Licodione <=> S-Adenosyl-L-homocysteine + 2'-O-Methyllicodione
Limonoate D-ring-lactone + H2O <=> Limonoate
UDP-glucose + Acetone cyanohydrin <=> UDP + Linamarin
Linoleate + Oxygen <=> (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoic acid
Linoleate <=> Rumenic acid
Melatonin + Oxygen <=> Formyl-N-acetyl-5-methoxykynurenamine
Melatonin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxymelatonin + [Oxidized NADPH---hemoprotein reductase] + H2O
Phthalate + Oxygen + NADH + H+ <=> cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+
ATP + Phytanate + CoA <=> AMP + Diphosphate + Phytanoyl-CoA
ATP + Protamine <=> ADP + O-Phosphoprotamine
S-Adenosyl-L-methionine + O-Demethylpuromycin <=> S-Adenosyl-L-homocysteine + Puromycin
Stachyose + H2O <=> Raffinose + D-Galactose
Stachyose + H2O <=> D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + D-Fructose
Leucocyanidin + NADP+ <=> Taxifolin + NADPH + H+
Taxifolin + Oxygen + NADH + H+ <=> 2,3-Dihydrogossypetin + NAD+ + H2O
Taxifolin + Oxygen + NADPH + H+ <=> 2,3-Dihydrogossypetin + NADP+ + H2O
Taxifolin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Dihydromyricetin + [Oxidized NADPH---hemoprotein reductase] + H2O
Eriodictyol + 2-Oxoglutarate + Oxygen <=> Taxifolin + Succinate + CO2
Testololactone + H2O <=> Testolate
Vicianose + Mandelonitrile <=> Vicianin + H2O
Vitamin K + NADH + H+ <=> Reduced Vitamin K + NAD+
Vitamin K + Oxidized dithiothreitol + H2O <=> Vitamin K epoxide + Dithiothreitol
ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg)
ATP + L-Aspartate + tRNA(Asn) <=> AMP + Diphosphate + L-Aspartyl-tRNA(Asn)
ATP + L-Asparagine + tRNA(Asn) <=> AMP + Diphosphate + L-Asparaginyl-tRNA(Asn)
ATP + L-Cysteine + tRNA(Cys) <=> AMP + Diphosphate + L-Cysteinyl-tRNA(Cys)
ATP + L-Glutamate + tRNA(Gln) <=> AMP + Diphosphate + L-Glutamyl-tRNA(Gln)
ATP + L-Glutamine + tRNA(Gln) <=> AMP + Diphosphate + Glutaminyl-tRNA
ATP + Glycine + tRNA(Gly) <=> AMP + Diphosphate + Glycyl-tRNA(Gly)
ATP + L-Histidine + tRNA(His) <=> AMP + Diphosphate + L-Histidyl-tRNA(His)
ATP + L-Isoleucine + tRNA(Ile) <=> AMP + Diphosphate + L-Isoleucyl-tRNA(Ile)
ATP + L-Leucine + tRNA(Leu) <=> AMP + Diphosphate + L-Leucyl-tRNA
ATP + L-Lysine + tRNA(Lys) <=> AMP + Diphosphate + L-Lysyl-tRNA
ATP + L-Methionine + tRNA(Met) <=> AMP + Diphosphate + L-Methionyl-tRNA
ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)
ATP + L-Proline + tRNA(Pro) <=> AMP + Diphosphate + L-Prolyl-tRNA(Pro)
ATP + L-Serine + tRNA(Ser) <=> AMP + Diphosphate + L-Seryl-tRNA(Ser)
ATP + L-Threonine + tRNA(Thr) <=> AMP + Diphosphate + L-Threonyl-tRNA(Thr)
ATP + L-Tryptophan + tRNA(Trp) <=> AMP + Diphosphate + L-Tryptophanyl-tRNA(Trp)
ATP + L-Valine + tRNA(Val) <=> AMP + Diphosphate + L-Valyl-tRNA(Val)
Cadaverine <=> Piperideine
Coformycin + NADP+ <=> 8-Oxocoformycin + NADPH + H+
Acetyl-CoA + Cysteamine <=> CoA + S-Acetylthioethanolamine
D-Fuconate <=> 2-Dehydro-3-deoxy-D-fuconate + H2O
L-Dopachrome + 3,4-Dihydroxy-L-phenylalanine <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + Dopaquinone
L-Dopachrome <=> 5,6-Dihydroxyindole-2-carboxylate
L-Dopachrome <=> 5,6-Dihydroxyindole + CO2
5alpha-Ergosta-7,22-diene-3beta,5-diol <=> Ergosterol + H2O
Ergosterol + hn <=> Vitamin D2
(3Z)-Phytochromobilin + 2 Oxidized ferredoxin <=> Biliverdin + 2 Reduced ferredoxin
UDP-alpha-D-galactose + Galactogen <=> UDP + (1->6)-beta-D-Galactosylgalactogen
UDP-glucose + Gibberellin A3 <=> UDP + Gibberellin 2-O-beta-D-glucoside
UDP-glucose + Glycogenin <=> UDP + alpha-D-Glucosylglycogenin
Hemoglobin + Oxygen <=> Oxyhemoglobin
Hemoglobin <=> Globin + Heme
Bis-D-fructose 2',1:2,1'-dianhydride + H2O <=> Inulobiose
UDP-glucose + Isovitexin <=> Isovitexin 2''-O-beta-D-glucoside + UDP
2-Quinolinecarboxylic acid + Acceptor + H2O <=> 4-Hydroxy-2-quinolinecarboxylic acid + Reduced acceptor
L-Fuconate <=> 2-Dehydro-3-deoxy-L-fuconate + H2O
Lanosterol + NADPH + H+ <=> 24,25-Dihydrolanosterol + NADP+
ATP + D-Lombricine <=> ADP + N-Phospho-D-lombricine
Dihydrocoumarin + H2O <=> 3-(2-Hydroxyphenyl)propanoate
(S)-2-Methylmalate <=> Mesaconate + H2O
Mesaconate + H2O <=> L-threo-3-Methylmalate
Mesaconate + CoA <=> 2-Methylfumaryl-CoA + H2O
L-threo-3-Methylaspartate <=> Mesaconate + Ammonia
Morphine + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O <=> Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen
Oripavine + 2-Oxoglutarate + Oxygen <=> Morphinone + Formaldehyde + Succinate + CO2
Diphosphate + N-D-Ribosylpurine <=> Orthophosphate + Purine mononucleotide
3'-Phosphoadenylyl sulfate + Psychosine <=> Adenosine 3',5'-bisphosphate + Psychosine sulfate
S-Adenosyl-L-methionine + Thiopurine <=> S-Adenosyl-L-homocysteine + 6-Methylmercaptopurine
Triacetate lactone + H2O <=> Triacetate
Raucaffricine + H2O <=> Vomilenine + D-Glucose
5,10-Methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH2 <=> Tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD
(Alginate)n <=> Oligouronide with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl group
(S,S)-Butane-2,3-diol + NAD+ <=> (S)-Acetoin + NADH + H+
gamma-Butyrolactone + H2O <=> 4-Hydroxyacid
3-(2-Hydroxyphenyl)propanoate + NAD+ <=> trans-2-Hydroxycinnamate + NADH + H+
UDP-glucose + trans-2-Hydroxycinnamate <=> UDP + trans-beta-D-Glucosyl-2-hydroxycinnamate
Actinomycin + H2O <=> Actinomycinic monolactone
Albendazole + Oxygen + NADPH + H+ <=> Albendazole S-oxide + NADP+ + H2O
11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADP+ <=> Aldosterone + NADPH + H+
11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + Acceptor <=> Aldosterone + Reduced acceptor
Chlordecone alcohol + NADP+ <=> Chlordecone + NADPH + H+
Choloyl-CoA + Glycine <=> CoA + Glycocholate
Propanoyl-CoA + Choloyl-CoA <=> CoA + 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA
Choloyl-CoA + Taurine <=> CoA + Taurocholate
S-Adenosyl-L-methionine + Columbamine <=> S-Adenosyl-L-homocysteine + Palmatine
Isocorypalmine + 2 Oxygen <=> Columbamine + 2 Hydrogen peroxide
(24R,24(1)R)-Fucosterol epoxide <=> Desmosterol + Acetaldehyde
Desmosterol + Acceptor <=> 7-Dehydrodesmosterol + Reduced acceptor
Desmosterol + S-Adenosyl-L-methionine <=> 24-Methylenecholesterol + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + N6-(Delta2-Isopentenyl)-adenine <=> 5'-Methylthioadenosine + Discadenine
Feruloyl-CoA + D-Galactarate <=> CoA + O-Feruloylgalactarate
Octadecanal + Oxygen + 2 NADPH + 2 H+ <=> Heptadecane + Formate + H2O + 2 NADP+
S-Adenosyl-L-methionine + Isoorientin <=> S-Adenosyl-L-homocysteine + Isoscoparine
(2S)-2-{[1-(R)-Carboxyethyl]amino}pentanoate + NAD+ + H2O <=> L-Norvaline + Pyruvate + NADH + H+
Threonate + NAD+ <=> 3-Dehydro-L-threonate + NADH + H+
Thyroxine + Reduced acceptor <=> Triiodothyronine + Iodide + Acceptor + H+
(2S,3S)-2-Hydroxytridecane-1,2,3-tricarboxylate + CoA <=> Lauroyl-CoA + H2O + Oxaloacetate
Rifamycin B + Oxygen <=> Rifamycin O + Hydrogen peroxide
(6S)-Hydroxyhyoscyamine + 2-Oxoglutarate + Oxygen <=> Scopolamine + Succinate + CO2 + H2O
3-alpha(S)-Strictosidine + H2O <=> Tryptamine + Secologanin
Stipitatonate + H2O <=> Stipitatate + CO2
Trichodiene <=> Nivalenol
Protoaphin aglucone <=> Xanthoaphin + H2O
beta-Lactam + H2O <=> Substituted beta-amino acid
ATP + tau-Protein <=> ADP + O-Phospho-tau-protein
(+)-cis-Sabinol + NAD+ <=> (+)-Sabinone + NADH + H+
S-Adenosyl-L-methionine + 2-Iodophenol <=> S-Adenosyl-L-homocysteine + 2-Iodophenol methyl ether
3-Oxododecanoic acid <=> 2-Undecanone + CO2
3-Oxosteroid + Acceptor <=> 3-Oxo-Delta1-steroid + Reduced acceptor
(5-L-Glutamyl)-L-amino acid <=> 5-Oxoproline + L-Amino acid
epsilon-Caprolactone + H2O <=> 6-Hydroxyhexanoic acid
7beta-Hydroxysteroid + NADP+ <=> 7-Oxosteroid + NADPH + H+
ATP + Acylglycerol <=> ADP + Acyl-sn-glycerol 3-phosphate
Acyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol
2,3-Dehydroacyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol
Aminoacetone + CO2 <=> L-2-Amino-3-oxobutanoic acid
(R)-1-Aminopropan-2-ol + NAD+ <=> Aminoacetone + NADH + H+
Acetyl-CoA + 2-Arylethylamine <=> CoA + N-Acetyl-2-arylethylamine
Asparagusate + NADH + H+ <=> 3-Sulfanyl-2-(sulfanylmethyl)propanoate + NAD+
Biotinyl-5'-AMP + CoA <=> AMP + Biotinyl-CoA
23,24-Dihydrocucurbitacin B + NAD+ <=> Cucurbitacin B + NADH + H+
23,24-Dihydrocucurbitacin B + NADP+ <=> Cucurbitacin B + NADPH + H+
Cycloartenol <=> Zymosterol
ATP + D-Hamamelose <=> ADP + D-Hamamelose 2(1)-phosphate
Acetyl-CoA + Gentamicin C <=> CoA + N3-Acetylgentamicin C
GDP-mannose + Heteroglycan <=> GDP + 2-alpha-D-Mannosylheteroglycan
GDP-mannose + Heteroglycan <=> GDP + 3-alpha-D-Mannosylheteroglycan
ATP + Hygromycin B <=> ADP + 7''-O-Phosphohygromycin
L-Lysyl-tRNA + Phosphatidylglycerol <=> tRNA(Lys) + 3-O-L-Lysyl-1-O-phosphatidylglycerol
L-Rhamnono-1,4-lactone + H2O <=> L-Rhamnonate
L-Rhamnonate <=> 2-Dehydro-3-deoxy-L-rhamnonate + H2O
Cycloeucalenol <=> Obtusifoliol
Octanoyl-CoA + NADP+ <=> trans-Oct-2-enoyl-CoA + NADPH + H+
Octanoyl-CoA + FAD <=> trans-Oct-2-enoyl-CoA + FADH2
Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA
Octanoyl-CoA + L-Carnitine <=> CoA + L-Octanoylcarnitine
ATP + Oleandomycin <=> ADP + Oleandomycin 2'-O-phosphate
Nonane-4,6-dione + H2O <=> Pentan-2-one + Butanoic acid
Isopiperitenone <=> Piperitenone
Pregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxypregnenolone + [Oxidized NADPH---hemoprotein reductase] + H2O
Pregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 21-Hydroxypregnenolone + [Oxidized NADPH---hemoprotein reductase] + H2O
ATP + Taurocyamine <=> ADP + N-Phosphotaurocyamine
5,12-Dihydroxanthommatin + NAD+ <=> Xanthommatin + NADH + H+
S-Adenosyl-L-methionine + m7G(5')pppAm-mRNA <=> S-Adenosyl-L-homocysteine + m7G(5')pppm6Am-mRNA
tRNA guanine + Queuine <=> tRNA queuine + Guanine
(R)-Mandelate + NAD+ <=> alpha-Oxo-benzeneacetic acid + NADH + H+
(S)-Mandelate <=> (R)-Mandelate
(S)-Mandelate + NAD+ <=> alpha-Oxo-benzeneacetic acid + NADH + H+
(S)-Mandelate + Acceptor <=> alpha-Oxo-benzeneacetic acid + Reduced acceptor
(S)-Mandelate + Tetrahydropteridine + Oxygen <=> (S)-4-Hydroxymandelate + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
Pyruvate oxime + Acetone <=> Pyruvate + Acetone oxime
UDP-glucose + Anthocyanidin <=> UDP + Anthocyanidin 3-O-beta-D-glucoside
Aristolochene <=> PR-toxin
2 Dimethylallyl diphosphate + Aspulvinone E <=> 2 Diphosphate + Aspulvinone H
Blasticidin S + H2O <=> Deaminohydroxyblasticidin S + Ammonia
Cellotetraose + H2O <=> Cellotriose + D-Glucose
Cellopentaose + H2O <=> Cellotetraose + D-Glucose
Deoxylimonate + H2O <=> Deoxylimononic acid D-ring-lactone
Monoamide of dicarboxylate + H2O <=> Dicarboxylate + Ammonia
S-Adenosyl-L-methionine + G(5')pppPur-mRNA + H+ <=> S-Adenosyl-L-homocysteine + m7G(5')pppR-mRNA
Gibberellin A44 diacid + 2-Oxoglutarate + Oxygen <=> Gibberellin A19 + Succinate + CO2 + H2O
Gibberellin A19 + 2 2-Oxoglutarate + 2 Oxygen <=> Gibberellin A20 + 3 CO2 + 2 Succinate + H2O
Gibberellin A20 + 2-Oxoglutarate + Oxygen <=> Gibberellin A29 + Succinate + CO2
2,5-Dioxopiperazine + H2O <=> Glycylglycine
L-Hyoscyamine + 2-Oxoglutarate + Oxygen <=> (6S)-Hydroxyhyoscyamine + Succinate + CO2
L-Leucyl-tRNA + Protein <=> tRNA(Leu) + L-Leucyl-protein
Linoleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> gamma-Linolenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
Phylloquinone + NADH + H+ <=> Phylloquinol + NAD+
Plastoquinol + 2 Oxidized plastocyanin + 2 H+ <=> Plastoquinone + 2 Reduced plastocyanin + 4 H+
Reduced putidaredoxin + (+)-Camphor + Oxygen <=> (+)-exo-5-Hydroxycamphor + Oxidized putidaredoxin + H2O
ATP + Sedoheptulose <=> ADP + Sedoheptulose 1-phosphate
3-alpha(S)-Strictosidine + H2O <=> Strictosidine aglycone + D-Glucose
Trypanothione + NADP+ <=> Trypanothione disulfide + NADPH + H+
ATP + Glutathionylspermidine + Glutathione <=> ADP + Orthophosphate + Trypanothione
beta-Carotene <=> Lycopene
gamma-Carotene <=> beta-Carotene
dTDP-galactose + H2O + 2 NAD+ <=> dTDP-D-galacturonate + 2 NADH + 2 H+
(2S)-Flavan-4-ol + NADP+ <=> (2S)-Flavanone + NADPH + H+
GTP + (5')ppPur-mRNA <=> Diphosphate + G(5')pppPur-mRNA
GDP-mannose + Glucomannan <=> GDP + Glucomannan longer by one mannose unit
(S)-2-Haloacid + H2O <=> (R)-2-Hydroxyacid + Halide
(S)-Reticuline + Oxygen <=> (S)-Scoulerine + Hydrogen peroxide
S-Adenosyl-L-methionine + 3'-Hydroxy-N-methyl-(S)-coclaurine <=> S-Adenosyl-L-homocysteine + (S)-Reticuline + H+
(S)-Reticuline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 1,2-Dehydroreticuline + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(S)-Scoulerine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-Cheilanthifoline + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
S-Adenosyl-L-methionine + (S)-Scoulerine <=> S-Adenosyl-L-homocysteine + Isocorypalmine
11-cis-Retinal <=> Iodopsin
2,3-Dehydroacyl-CoA + 2-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol
ATP + 5'-Dephospho-DNA <=> ADP + 5'-Phospho-DNA
Acyl phosphate + D-Hexose <=> Carboxylate + D-Hexose phosphate
(S)-N-Methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Allocryptopine + [Oxidized NADPH---hemoprotein reductase] + H2O
Chlorophyllide + NADP+ <=> Protochlorophyllide + NADPH + H+
Corticosterone + NAD+ <=> 11-Dehydrocorticosterone + NADH + H+
Corticosterone + NADP+ <=> 11-Dehydrocorticosterone + NADPH + H+
11beta-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Corticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADP+ <=> Corticosterone + NADPH + H+
11-Deoxycorticosterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Corticosterone + 2 Oxidized ferredoxin + H2O
D-Ribosyl-base + Base <=> D-Ribosyl-base + Base
2,2-Dialkylglycine + Pyruvate <=> Dialkyl ketone + CO2 + L-Alanine
Lauroyl-CoA + NADP+ <=> 2-trans-Dodecenoyl-CoA + NADPH + H+
Lauroyl-CoA + FAD <=> 2-trans-Dodecenoyl-CoA + FADH2
Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA
(3S,4S)-3-Hydroxytetradecane-1,3,4-tricarboxylate + CoA <=> Lauroyl-CoA + H2O + 2-Oxoglutarate
Geissoschizine + NADP+ <=> 4,21-Dehydrogeissoschizine + NADPH
Sinapoyl-CoA + D-Glucono-1,5-lactone <=> CoA + O-Sinapoylglucarolactone
L-Arginyl-tRNA(Arg) + Protein <=> tRNA(Arg) + L-Arginyl-protein
Leukotriene B4 + NAD+ <=> 12-Keto-leukotriene B4 + H+ + NADH
Leukotriene B4 + NADP+ <=> 12-Keto-leukotriene B4 + H+ + NADPH
Leukotriene B4 + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-OH-Leukotriene B4 + [Oxidized NADPH---hemoprotein reductase] + H2O
Leukotriene C4 + Amino acid <=> Leukotriene D4 + 5-L-Glutamyl amino acid
Maleylpyruvate <=> 3-Fumarylpyruvate
(S)-Methylmalonate semialdehyde + NAD+ + H2O <=> Methylmalonate + NADH + H+
5-Methylbarbiturate + 2 H2O <=> Methylmalonate + Urea
Methylmalonate + Hydrogen peroxide <=> (S)-Methylmalonate semialdehyde + Oxygen + H2O
Methylmalonate <=> (S)-Methylmalonate semialdehyde
N-Acetylisatin <=> N-Acetylindoxyl + Oxygen
[Peptide]-(2S)-2-hydroxyglycine <=> [Peptide]-amide + Glyoxylate
Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine
ATP + Ubiquitin + Protein lysine <=> AMP + Diphosphate + Protein N-ubiquityllysine
ATP + Protoporphyrin + Magnesium cation + H2O <=> ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+
Thromboxane A2 + H2O <=> Thromboxane B2
UDP-L-rhamnose + NADP+ <=> UDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+
UDP-L-rhamnose + Flavonol 3-O-beta-D-glucoside <=> UDP + Flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside]
UDP-glucosamine <=> UDP-galactosamine
1,2-Dihydrosantonin + NAD+ <=> alpha-Santonin + NADH + H+
1,2-Dihydrosantonin + NADP+ <=> alpha-Santonin + NADPH + H+
Acetyl-CoA + (E)-Glutaconate <=> Acetate + Glutaconyl-1-CoA
1-Methyladenosine + H2O <=> 1-Methyladenine + D-Ribose
10-Hydroxydecanoic acid + NAD+ <=> 10-Oxodecanoate + NADH + H+
2-Aminomuconate + H2O <=> gamma-Oxalocrotonate + Ammonia
2-Aminomuconate semialdehyde + NAD+ + H2O <=> 2-Aminomuconate + H+ + NADH
Benzene-1,2,4-triol + Oxygen <=> 2-Maleylacetate
2-Maleylacetate <=> 3-Hydroxy-cis,cis-muconate
cis-4-Carboxymethylenebut-2-en-4-olide + H2O <=> 2-Maleylacetate
(S)-3-Methyl-2-oxopentanoic acid <=> 2-Methylbutanal + CO2
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
2-Methylmaleate + H2O <=> D-threo-3-Methylmalate
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
N1-Acetylspermine + Oxygen + H2O <=> Spermidine + 3-Acetamidopropanal + Hydrogen peroxide
beta-Nitropropanoate + NADP+ <=> 3-Nitroacrylate + NADPH + H+
S-Alkyl-L-cysteine S-oxide <=> Alkyl sulfenate + Dehydroalanine
Acetyl-CoA + D-Phenylalanine <=> CoA + N-Acetyl-D-phenylalanine
dATP + Depurinated DNA <=> Deoxyribose triphosphate + DNA adenine
Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O
Glycyrrhizinate + H2O <=> 1,2-beta-D-Glucuronosyl-D-glucuronate + Glycyrrhetinate
Latia luciferin + Reduced acceptor + 2 Oxygen <=> Oxidized Latia luciferin + hn + Formate + Acceptor + CO2 + H2O
2-Methyleneglutarate <=> Methylitaconate
Monocarboxylic acid amide + H2O <=> Carboxylate + Ammonia
Acetyl-CoA + Alkane-alpha,omega-diamine <=> CoA + N-Acetyldiamine
N-Acetylindoxyl <=> Indoxyl
[Peptide]-glycine + 2 Ascorbate + Oxygen <=> [Peptide]-(2S)-2-hydroxyglycine + 2 Monodehydroascorbate + H2O
Protein dithiol + NAD+ <=> Protein disulfide + NADH + H+
Protein dithiol + NADP+ <=> Protein disulfide + NADPH + H+
Protein dithiol + Glutathione disulfide <=> Protein disulfide + 2 Glutathione
R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate
n Isopentenyl diphosphate <=> cis-1,4-Polyisoprene + n Diphosphate
Sinapyl alcohol + NADP+ <=> Sinapoyl aldehyde + NADPH + H+
Sinapyl alcohol <=> Syringyl lignin
ATP + beta-D-Fructose <=> ADP + beta-D-Fructose 6-phosphate
Sucrose 6-phosphate + H2O <=> D-Fructose + D-Glucose 6-phosphate
S-Adenosyl-L-methionine + m7G(5')pppR-mRNA <=> S-Adenosyl-L-homocysteine + m7G(5')pppRm-mRNA
L-Cysteine + 'Activated' tRNA <=> L-Serine + tRNA containing a thionucleotide
GDP-mannose + Phosphomannan <=> GMP + Phosphomannan mannosephosphate
(S)-Allantoin <=> (R)(-)-Allantoin
Pantothenate + 2 Reduced acceptor <=> Pantothenol + 2 Acceptor + H2O
UDP-D-xylose + 1,4-beta-D-Xylan <=> UDP + 1,4-beta-D-Xylan
2',3'-Cyclic CMP + H2O <=> 3'-CMP
3-Methyloxindole + NADP+ <=> 3-Methyleneoxindole + NADPH + H+
ATP + 4-Chlorobenzoate + CoA <=> AMP + Diphosphate + 4-Chlorobenzoyl-CoA
20alpha,22beta-Dihydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 4-Methylpentanal + Pregnenolone + 2 H2O + 2 Oxidized adrenal ferredoxin
S-Adenosyl-L-methionine + 6-Hydroxymellein <=> S-Adenosyl-L-homocysteine + 6-Methoxymellein
beta-Alanyl-L-arginine + H2O <=> beta-Alanine + Amino acid(Arg-)
L-Formylkynurenine + H2O <=> Formylanthranilate + L-Alanine
Glutaconyl-1-CoA + H2O <=> 2-Hydroxyglutaryl-CoA
S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine
ATP + Hypotaurocyamine <=> ADP + N-Phosphohypotaurocyamine
L-Methionyl-tRNA + 10-Formyltetrahydrofolate <=> Tetrahydrofolate + N-Formylmethionyl-tRNA
L-Rhamnofuranose + NAD+ <=> L-Rhamnono-1,4-lactone + NADH + H+
N-Methyltyramine + S-Adenosyl-L-methionine <=> Hordenine + S-Adenosyl-L-homocysteine
ATP + O-Alkylglycerone <=> ADP + O-Alkylglycerone phosphate
(-)-Perillyl alcohol + NAD+ <=> Perillyl aldehyde + NADH + H+
3'-Phosphoadenylyl sulfate + Phenolic steroid <=> Adenosine 3',5'-bisphosphate + Steroid O-sulfate
Precorrin 2 + NAD+ <=> Sirohydrochlorin + NADH + H+
S-Adenosyl-L-methionine + Precorrin 2 <=> S-Adenosyl-L-homocysteine + Precorrin 3A + H+
2 S-Adenosyl-L-methionine + Uroporphyrin III <=> 2 S-Adenosyl-L-homocysteine + Sirohydrochlorin
Triiodothyronine + 2-Oxoglutarate <=> 3,5,3'-Triiodothyropyruvate + L-Glutamate
3-Iodo-L-tyrosine + 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Triiodothyronine + Dehydroalanine + 2 H2O
Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Xanthurenic acid + S-Adenosyl-L-methionine <=> 8-Methoxykynurenate + S-Adenosyl-L-homocysteine
Glutathione + [Glu(-Cys)]n-Gly <=> Glycine + [Glu(-Cys)]n+1-Gly
2,5-Dihydro-5-oxofuran-2-acetate <=> cis,cis-Muconate
2'-Hydroxydihydrodaidzein + NADP+ <=> 2'-Hydroxydaidzein + NADPH + H+
2-Butyne-1,4-diol + NAD+ <=> 4-Hydroxy-2-butynal + NADH + H+
2-Hydroxybiphenyl + Oxygen + NADH + H+ <=> Biphenyl-2,3-diol + NAD+ + H2O
Sinapoyl-CoA + Hydroxymalonate <=> CoA + Sinapoyltartronate
2-Hydroxymuconate <=> gamma-Oxalocrotonate
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-(ADP)-2-phosphoglycerate + H2O <=> 3-(ADP)-glycerate + Orthophosphate
3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O
3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O
Hydroiodic acid + 3,5-Diiodo-L-tyrosine <=> 3-Iodo-L-tyrosine + Iodine
Chenodeoxycholate + CoA <=> Chenodeoxycholoyl-CoA + H2O
Glycochenodeoxycholate + H2O <=> Chenodeoxycholate + Glycine
Taurochenodeoxycholate + H2O <=> Chenodeoxycholate + Taurine
Chenodeoxycholate + FADH2 <=> Lithocholic acid + FAD + H2O
Aryl dialkyl phosphate + H2O <=> Dialkyl phosphate + Phenol
Estrone 3-sulfate + H2O <=> Sulfate + Estrone
UDP-alpha-D-galactose + Glycosaminoglycan <=> UDP + D-Galactosylglycosaminoglycan
Pentachlorophenol + Oxygen + NADPH + H+ <=> Chloranil + Cl- + NADP+ + H2O
Protein glutamine + Alkylamine <=> Protein N5-alkylglutamine + Ammonia
Pyrimidodiazepine + Glutathione disulfide + H2O <=> 6-Pyruvoyltetrahydropterin + 2 Glutathione
UDP-sugar + H2O <=> UMP + alpha-D-Aldose 1-phosphate
3'-Phosphoadenylyl sulfate + Taurolithocholate <=> Adenosine 3',5'-bisphosphate + Taurolithocholate sulfate
Tetradecanoyl-CoA + NADP+ <=> trans-Tetradec-2-enoyl-CoA + NADPH + H+
Tetradecanoyl-CoA + FAD <=> trans-Tetradec-2-enoyl-CoA + FADH2
Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA
Tetradecanoyl-CoA + N-Terminal-glycyl-[protein] <=> CoA + N-Terminal-N-tetradecanoylglycyl-[protein]
[Pyruvate kinase] phosphate + H2O <=> [Pyruvate kinase] + Orthophosphate
(E,E)-Piperoyl-CoA + Piperidine <=> CoA + Piperine
(R)-2-Methylmalate + CO2 <=> Parapyruvate + H2O
UDP-glucose + 1,3-alpha-D-Glucan <=> UDP + 1,3-alpha-D-Glucan
2,4-Dichlorophenol + Oxygen + NADPH + H+ <=> 3,5-Dichlorocatechol + NADP+ + H2O
Anthraniloyl-CoA + Oxygen + 2 NADH + 2 H+ <=> 2-Amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NAD+
Anthraniloyl-CoA + Oxygen + 2 NADPH + 2 H+ <=> 2-Amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NADP+
Acetyl-CoA + 2-Hydroxyglutarate <=> Acetate + 2-Hydroxyglutaryl-CoA
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
ATP + 2-Methylpropanoate <=> ADP + 2-Methylpropanoyl phosphate
3-Chloro-L-alanine + Thioglycolate <=> S-Carboxymethyl-L-cysteine + Cl-
UDP-glucose + 4-Coumaryl alcohol <=> UDP + 4-Hydroxycinnamyl alcohol 4-D-glucoside
4-Hydroxycinnamyl alcohol 4-D-glucoside + H2O <=> 4-Coumaryl alcohol + D-Glucose
4-Coumaryl alcohol <=> p-Hydroxyphenyl lignin
Aldoxime + CO2 <=> 2-Oxoacid oxime
Benzyl thiocyanate <=> Benzyl isothiocyanate
L-Glutamine + D-Glutamyl-peptide <=> Ammonia + 5-L-Glutamyl-D-glutamyl-peptide
D-Glutamine + D-Glutamyl-peptide <=> Ammonia + 5-D-Glutamyl-D-glutamyl-peptide
S-Adenosyl-L-methionine + 16-Methoxy-2,3-dihydro-3-hydroxytabersonine <=> S-Adenosyl-L-homocysteine + Desacetoxyvindoline
Dodecanoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Dodecanoic acid
2 Ferricytochrome c3 + Hydrogen <=> 2 Ferrocytochrome c3 + 2 H+
Galactosylceramide + UDP-alpha-D-galactose <=> Digalactosylceramide + UDP
3'-Phosphoadenylyl sulfate + Galactosylceramide <=> Adenosine 3',5'-bisphosphate + Sulfatide
Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O
Digalactosylceramide + H2O <=> Galactosylceramide + D-Galactose
(Indol-3-yl)acetamide <=> 3-Indoleacetonitrile + H2O
Palmitoyl-CoA + Mucus glycoprotein <=> CoA + O-Palmitoylglycoprotein
Palmitoyl-CoA + Myelin proteolipid <=> CoA + Myelin proteolipid O-palmitoylprotein
ATP + Myosin heavy chain <=> ADP + Myosin heavy-chain phosphate
Acetyl-CoA + Hydroxylaminobenzene <=> CoA + N-(Acetyloxy)benzenamine
N-Acetylputrescine + H2O + Oxygen <=> N4-Acetylaminobutanal + Ammonia + Hydrogen peroxide
N-Formiminoglycine <=> Imidazolone + H2O
N-Methylputrescine + Oxygen + H+ <=> 1-Methylpyrrolinium + Hydrogen peroxide + Ammonia
6-Acetamido-3-aminohexanoate + 2-Oxoglutarate <=> 6-Acetamido-3-oxohexanoate + L-Glutamate
N6-Acetyl-L-lysine + 2-Oxoglutarate <=> 6-Acetamido-2-oxohexanoate + L-Glutamate
ATP + 2-Succinylbenzoate + CoA <=> AMP + Diphosphate + 2-Succinylbenzoyl-CoA
2-Succinylbenzoate + H2O <=> (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
Peptide tryptophan + Oxygen <=> Peptide formylkynurenine
S-Adenosyl-L-methionine + Phenylethanolamine <=> S-Adenosyl-L-homocysteine + N-Methylphenylethanolamine
Phosphatidylserine + H2O <=> 2-Acyl-sn-glycero-3-phosphoserine + Fatty acid
1-(5-Phospho-D-ribosyl)-ATP + H2O <=> Phosphoribosyl-AMP + Diphosphate
Photinus luciferin + Oxygen + ATP <=> Oxidized Photinus luciferin + hn + AMP + Diphosphate + CO2
Phosphoribosyl-AMP + H2O <=> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
Dimethylallyl diphosphate + AMP <=> Diphosphate + N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate
[Xanthine dehydrogenase] + Glutathione disulfide <=> [Xanthine oxidase] + 2 Glutathione
alpha-Pinene-oxide <=> (Z)-2-Methyl-5-isopropylhexa-2,5-dienal
1-Alkyl-2-acetyl-sn-glycerol + H2O <=> 1-Alkyl-sn-glycerol + Acetate
2-Acetamidofluorene + NAD+ + H2O <=> N-Hydroxy-2-acetamidofluorene + NADH + H+
2-Acetamidofluorene + NADP+ + H2O <=> N-Hydroxy-2-acetamidofluorene + NADPH + H+
2-Dehydro-D-glucose + Oxygen <=> 2-Dehydro-D-glucono-1,5-lactone + Hydrogen peroxide
2-Deoxy-D-gluconate + NAD+ <=> 3-Dehydro-2-deoxy-D-gluconate + NADH + H+
Malonyl-CoA + 3,4-Dichloroaniline <=> CoA + N-(3,4-Dichlorophenyl)-malonamate
3-Phosphonopyruvate + L-Glutamate <=> 2-Amino-3-phosphonopropanoate + 2-Oxoglutarate
3-Phosphonopyruvate <=> Phosphonoacetaldehyde + CO2
Triacylglycerol + 3beta-Hydroxysteroid <=> Diacylglycerol + 3beta-Hydroxysteroid ester
4-Acetamidobutanoyl-CoA + H2O <=> Acetate + 4-Aminobutanoyl-CoA
Acetyl-CoA + 5-Hydroxypentanoate <=> Acetate + 5-Hydroxypentanoyl-CoA
L-Glutaminyl-peptide <=> 5-Oxoprolyl-peptide + Ammonia
(+/-)-trans-Acenaphthene-1,2-diol + 2 NADP+ <=> Acenaphthenequinone + 2 NADPH + 2 H+
Anhydrotetracycline + Oxygen + NADPH + H+ <=> 5a,11a-Dehydrotetracycline + NADP+ + H2O
Benzene-1,2,4-triol + Oxygen <=> 3-Hydroxy-cis,cis-muconate
S-Adenosyl-L-methionine + Calmodulin L-lysine <=> S-Adenosyl-L-homocysteine + Calmodulin N6-methyl-L-lysine
Cypridina luciferin + Oxygen <=> Oxidized Cypridina luciferin + hn + CO2
Imidazole-4-acetaldehyde + NAD+ + H2O <=> Imidazole-4-acetate + NADH + H+
Imidazole-4-acetate + Oxygen + NADH + H+ <=> 4-Imidazolone-5-acetate + NAD+ + H2O
ATP + Imidazole-4-acetate + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O <=> ADP + Orthophosphate + 1-(5-Phosphoribosyl)imidazole-4-acetate + Diphosphate
N5-Acyl-L-ornithine ester + H2O <=> N5-Acyl-L-ornithine + Alcohol
UDP-glucose + N6-Alkylaminopurine <=> UDP + N6-Alkylaminopurine-7-beta-D-glucoside
Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein]
Peptide L-aspartate + 2-Oxoglutarate + Oxygen <=> Peptide 3-hydroxy-L-aspartate + Succinate + CO2
NAD+ + Peptide diphthamide <=> Nicotinamide + Peptide N-(ADP-D-ribosyl)diphthamide
Protein N(pi)-phospho-L-histidine + L-Sorbose <=> Protein histidine + Sorbose 1-phosphate
S-Adenosyl-L-methionine + Isocorypalmine <=> S-Adenosyl-L-homocysteine + Tetrahydropalmatine
Watasenia luciferin + Oxygen <=> Oxidized Watasenia luciferin + hn + CO2
beta-Cyclopiazonate + Acceptor <=> Cyclopiazonic acid + Reduced acceptor
GDP-L-fucose + beta-D-Galactosyl-R <=> GDP + alpha-L-Fucosyl-1,2-beta-D-galactoside
GDP-mannose + tRNA(Asp)-queuosine <=> GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine
3,4-Dihydroxyphenylacetaldehyde + Dopamine <=> (S)-Norlaudanosoline + H2O
1-Methylnicotinamide + Oxygen + H2O <=> N1-Methyl-4-pyridone-5-carboxamide + Hydrogen peroxide + H+
Toluene-cis-dihydrodiol + NAD+ <=> 2,3-Dihydroxytoluene + NADH + H+
2,3-Dihydroxytoluene + Oxygen <=> 2-Hydroxy-6-keto-2,4-heptadienoate
S-(2-Hydroxyacyl)glutathione + H2O <=> Glutathione + 2-Hydroxy carboxylate
O-Acetyl-L-serine + 3,4-Dihydroxypyridine + H+ <=> 3-(3,4-Dihydroxypyridin-1-yl)-L-alanine + Acetate
3-Dehydrosphinganine + FAD <=> 3-Ketosphingosine + FADH2
Indole-3-acetaldehyde oxime <=> 3-Indoleacetonitrile + H2O
Glucobrassicin + H2O <=> 3-Indoleacetonitrile + D-Glucose + Sulfate + Sulfur
3-Methylbutanoyl-CoA + FAD <=> 3-Methylcrotonyl-CoA + FADH2
3-Methylbutanoyl-CoA + Electron-transferring flavoprotein <=> 3-Methylcrotonyl-CoA + Reduced electron-transferring flavoprotein
3-Methylbutanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
3-Methylbutanoyl-CoA <=> Branched chain fatty acid
3alpha-Hydroxyglycyrrhetinate + NADP+ <=> 3-Oxoglycyrrhetinate + NADPH + H+
3-cis-Dodecenoyl-CoA <=> 2-trans-Dodecenoyl-CoA
4-Chlorobenzoyl-CoA + H2O <=> 4-Hydroxybenzoyl-CoA + Cl- + H+
(+)-Bornane-2,5-dione + Reduced FMN + Oxygen <=> 5-Oxo-1,2-campholide + FMN + H2O
Penicillin G + H2O <=> 6-Aminopenicillanate + Phenylacetic acid
Chondroitin <=> Dermatan
Ethyl (R)-3-hydroxyhexanoate + NADP+ <=> Ethyl 3-oxohexanoate + NADPH + H+
Ethyl (S)-3-hydroxyhexanoate + NADP+ <=> Ethyl 3-oxohexanoate + NADPH + H+
UDP-glucose + Hydroxyanthraquinone <=> UDP + Glucosyloxyanthraquinone
L-Glutamyl-tRNA(Glu) + NADPH + H+ <=> (S)-4-Amino-5-oxopentanoate + tRNA(Glu) + NADP+
Protein N(pi)-phospho-L-histidine + Maltose <=> Protein histidine + Maltose 6'-phosphate
N-Acetylmuramoyl-Ala + H2O <=> N-Acetylmuramate + L-Alanine
N-Benzoyl-D-arginine-4-nitroanilide + H2O <=> N-Benzoyl-D-arginine + 4-Nitroaniline
cis-1,2-Dihydronaphthalene-1,2-diol + NAD+ <=> Naphthalene-1,2-diol + NADH + H+
Naphthalene-1,2-diol + Oxygen <=> 2-Hydroxychromene-2-carboxylate
Oligoglycosylglucosylceramide + H2O <=> Oligoglycosylglucose + N-Acylsphingosine
Phorbol 12,13-dibutanoate + H2O <=> Phorbol 13-butanoate + Butanoic acid
Peptide-L-methionine + Thioredoxin disulfide + H2O <=> Peptide-L-methionine (S)-S-oxide + Thioredoxin
[Reduced NADPH---hemoprotein reductase] + Fatty acid + Oxygen <=> alpha-Hydroxy fatty acid + [Oxidized NADPH---hemoprotein reductase] + H2O
[Reduced NADPH---hemoprotein reductase] + Alkane + Oxygen <=> [Oxidized NADPH---hemoprotein reductase] + ROH + H2O
Transferrin[Fe(II)]2 + NAD+ + H+ <=> Transferrin[Fe(III)]2 + NADH
Transferrin[Fe(II)]2 <=> Apotransferrin + 2 Fe2+
[Protein]-S8-aminomethyldihydrolipoyllysine + Tetrahydrofolate <=> Dihydrolipoylprotein + 5,10-Methylenetetrahydrofolate + Ammonia
ATP + 1-Alkyl-sn-glycerol <=> ADP + 1-Alkyl-sn-glycero-3-phosphate
UDP-glucose + 13-Hydroxydocosanoic acid <=> UDP + 13-beta-D-Glucosyloxydocosanoate
2,6-Dihydroxypyridine + Oxygen + NADH + H+ <=> 2,3,6-Trihydroxypyridine + NAD+ + H2O
2-Oxohept-3-enedioate + H2O <=> 4-Hydroxy-2-oxo-heptanedioate
2-Oxohept-3-enedioate + H2O <=> 2,4-Dihydroxyhept-2-enedioate
5-Carboxy-2-oxohept-3-enedioate <=> 2-Oxohept-3-enedioate + CO2
2-Oxohept-3-enedioate <=> 2-Hydroxyhepta-2,4-dienedioate
3-Hydroxy-L-glutamate <=> 4-Amino-3-hydroxybutanoate + CO2
3-Hydroxybenzyl alcohol + NADP+ <=> 3-Hydroxybenzaldehyde + NADPH + H+
3-Hydroxyisovaleryl-CoA <=> 3-Methylcrotonyl-CoA + H2O
ATP + 3-Methylcrotonyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-Methylglutaconyl-CoA
Lithocholic acid + NAD+ <=> 3-Oxo-5beta-cholanate + NADH + H+
4-Chlorophenylacetonitrile + 2 H2O <=> 4-Chlorophenylacetate + Ammonia
4-Methylumbelliferyl acetate + H2O <=> 4-Methylumbelliferone + Acetate
5-Acetamidopentanoate + NADH + H+ + CO2 <=> 6-Acetamido-2-oxohexanoate + NAD+ + H2O
ATP + 5-Methylthio-D-ribose <=> ADP + S-Methyl-5-thio-D-ribose 1-phosphate
ATP + 5-Phosphoribosylamine + Glycine <=> ADP + Orthophosphate + 5'-Phosphoribosylglycinamide
S-Adenosyl-L-methionine + Cytochrome c L-lysine <=> S-Adenosyl-L-homocysteine + Cytochrome c N6-methyl-L-lysine
N-Acetyl-D-galactosaminoglycan + H2O <=> D-Galactosaminoglycan + Acetate
Isopenicillin N <=> Penicillin N
Nicotinate D-ribonucleotide + Dimethylbenzimidazole <=> Nicotinate + N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H+
Glycoprotein phosphatidylinositol + H2O <=> Phosphatidate + Glycoprotein inositol
2-Succinylbenzoyl-CoA <=> 1,4-Dihydroxy-2-naphthoate + CoA
(+)-cis-3,4-Dihydrophenanthrene-3,4-diol + NAD+ <=> Phenanthrene-3,4-diol + NADH + H+
2-Aminoethylphosphonate + Pyruvate <=> Phosphonoacetaldehyde + L-Alanine
Dimethylsulfonioacetate + L-Homocysteine <=> S-Methylthioglycolate + L-Methionine + H+
Tetrahydroxypteridine <=> Xanthine-8-carboxylate
Transferrin[Fe(III)]2 <=> Apotransferrin + 2 Fe3+
[Glycogen-synthase D] + H2O <=> [Glycogen-synthase I] + Orthophosphate
ATP + alpha,omega-Dicarboxylic acid + CoA <=> AMP + Diphosphate + omega-Carboxyacyl-CoA
Geranylgeranyl diphosphate + sn-Glycerol 1-phosphate <=> Diphosphate + 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
(5-L-Glutamyl)-peptide + Amino acid <=> Peptide + 5-L-Glutamyl amino acid
(S)-4-Hydroxymandelate + Acceptor <=> 4-Hydroxyphenylglyoxylate + Reduced acceptor
(S)-4-Hydroxymandelate <=> (R)-4-Hydroxymandelate
2-Acyl-1-alkyl-sn-glycero-3-phosphate + H2O <=> 1-Alkyl-2-acylglycerol + Orthophosphate
21-Hydroxypregnenolone + NAD+ <=> 11-Deoxycorticosterone + NADH + H+
11-Deoxycorticosterone <=> 20-Hydroxy-3-oxopregn-4-en-21-al
16alpha-Hydroxyprogesterone <=> 16-Dehydroprogesterone + H2O
2-Carboxy-D-arabinitol 1-phosphate + H2O <=> 2-Carboxy-D-arabinitol + Orthophosphate
Deoxynucleoside + Base <=> Deoxynucleoside + Base
S-Adenosyl-L-methionine + (E)-2-Methylpropanal oxime <=> S-Adenosyl-L-homocysteine + 2-Methylpropanal O-methyloxime
(S)-3-Hydroxydodecanoyl-CoA <=> 2-trans-Dodecenoyl-CoA + H2O
3-Hydroxy-L-kynurenine + 2-Oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-Glutamate
3-Hydroxy-L-kynurenine <=> 3-Hydroxykynurenamine + CO2
O-Phospho-L-serine + 2-Oxoglutarate <=> 3-Phosphonooxypyruvate + L-Glutamate
6-Acetamido-2-oxohexanoate + H2O <=> Acetate + 6-Amino-2-oxohexanoate
6-Amino-2-oxohexanoate <=> Delta1-Piperideine-2-carboxylate + H2O
NAD+ + ADP-D-ribosyl-acceptor <=> Nicotinamide + ADP-D-ribosyl-acceptor + H+
2-Hydroxyethylenedicarboxylate <=> Acetylenedicarboxylate + H2O
Coproporphyrinogen III + 3 Oxygen <=> Coproporphyrin III + 3 Hydrogen peroxide
UDP-glucose + D-Mannosylglycoprotein <=> UMP + 6-(D-Glucose-1-phospho)-D-mannosylglycoprotein
6-(D-Glucose-1-phospho)-D-mannosylglycoprotein + H2O <=> D-Glucose 1-phosphate + D-Mannosylglycoprotein
UDP-N-acetyl-D-galactosamine + Globoside <=> UDP + N-Acetyl-D-galactosaminyl-N-Acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
Globoside + N-Acetyl-D-galactosamine <=> N-Acetyl-D-galactosaminyl-N-Acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide + H2O
alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-Acetyl-D-galactosamine <=> Globoside + H2O
(S)-3-(Imidazol-5-yl)lactate + NAD+ <=> Imidazol-5-yl-pyruvate + NADH + H+
(S)-3-(Imidazol-5-yl)lactate + NADP+ <=> Imidazol-5-yl-pyruvate + NADPH + H+
L-Alanine + (S)-Methylmalonate semialdehyde <=> Pyruvate + L-3-Aminoisobutanoate
L-3-Aminoisobutanoate + 2-Oxoglutarate <=> (S)-Methylmalonate semialdehyde + L-Glutamate
N2-Succinyl-L-arginine + 2 H2O <=> N2-Succinyl-L-ornithine + CO2 + 2 Ammonia
S-Adenosyl-L-methionine + Protein L-isoaspartate <=> S-Adenosyl-L-homocysteine + Protein L-isoaspartate methyl ester
alpha-Amino acid ester + H2O <=> alpha-Amino acid + Alcohol
Acetyl-CoA + [alpha-Tubulin]-L-lysine <=> CoA + [alpha-Tubulin]-N6-acetyl-L-lysine
(2,1-beta-D-Fructosyl)n(m) + (2,1-beta-D-Fructosyl)n(n) <=> (2,1-beta-D-Fructosyl)n(m-1) + (2,1-beta-D-Fructosyl)n(n+1)
Sucrose + (2,1-beta-D-Fructosyl)n <=> D-Glucose + (2,1-beta-D-Fructosyl)n
2,3,4,5-Tetrahydrodipicolinate + NAD+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H+
2,3,4,5-Tetrahydrodipicolinate + NADP+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+
(2R,4S)-2,4-Diaminopentanoate + H2O + NAD+ <=> 2-Amino-4-oxopentanoic acid + Ammonia + NADH + H+
(2R,4S)-2,4-Diaminopentanoate + NADP+ + H2O <=> 2-Amino-4-oxopentanoic acid + NADPH + Ammonia + H+
Bis(2-ethylhexyl)phthalate + H2O <=> Mono-(2-ethylhexyl)phthalate + 2-Ethylhexan-1-ol
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA + NAD+ <=> 2-Methylacetoacetyl-CoA + NADH + H+
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA <=> 2-Methylbut-2-enoyl-CoA + H2O
2-Methylbut-2-enoyl-CoA + 13-Hydroxylupanine <=> CoA + 13-(2-Methylcrotonoyl)oxylupanine
3-Phospho-D-erythronate <=> Phosphoenol-4-deoxy-3-tetrulosonate + H2O
ATP + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine <=> ADP + Orthophosphate + Aminoimidazole ribotide
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <=> Aminoimidazole ribotide + CO2
4-Phospho-D-erythronate + NAD+ <=> 2-Oxo-3-hydroxy-4-phosphobutanoate + NADH + H+
Oxalyl-CoA + L-2,3-Diaminopropanoate <=> CoA + 3-(Carboxycarbonylamino)-L-alanine
L-Asparaginyl-tRNA(Asn) + L-Glutamate + Orthophosphate + ADP <=> L-Aspartyl-tRNA(Asn) + L-Glutamine + ATP + H2O
3'-Phosphoadenylyl sulfate + L-Tyrosine methyl ester <=> Adenosine 3',5'-bisphosphate + L-Tyrosine methyl ester 4-sulfate
N-Formimino-L-aspartate <=> 4-Imidazolone-5-acetate + H2O
CTP + N-Glycoloyl-neuraminate <=> Diphosphate + CMP-N-glycoloylneuraminate
Dolichyl diphosphooligosaccharide + Protein asparagine <=> Dolichyl diphosphate + Glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to protein L-asparagine
N2-Succinyl-L-ornithine + 2-Oxoglutarate <=> N-Succinyl-L-glutamate 5-semialdehyde + L-Glutamate
Prephytoene diphosphate <=> Diphosphate + 15-cis-Phytoene
cis-4-Hydroxy-D-proline + Oxygen <=> 1-Pyrroline-4-hydroxy-2-carboxylate + Hydrogen peroxide
dTDP-L-dihydrostreptose + Streptidine 6-phosphate <=> dTDP + O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate
gamma-Oxalocrotonate + H2O <=> 4-Hydroxy-2-oxopentanoate + CO2
2-Methylprop-2-enoyl-CoA + H2O <=> (S)-3-Hydroxyisobutyryl-CoA
(S)-3-Methyl-2-oxopentanoic acid + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
Phosphatidylcholine + Dolichol <=> Acyldolichol + 1-Acyl-sn-glycero-3-phosphocholine
4-Nitroquinoline N-oxide + 2 NADH + 2 H+ <=> 4-Hydroxyaminoquinoline N-oxide + 2 NAD+ + H2O
4-Nitroquinoline N-oxide + 2 NADPH + 2 H+ <=> 4-Hydroxyaminoquinoline N-oxide + 2 NADP+ + H2O
ATP + D-4'-Phosphopantothenate + L-Cysteine <=> AMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine
CTP + D-4'-Phosphopantothenate + L-Cysteine <=> CMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine
D-4-Hydroxyphenylglycine + 2-Oxoglutarate <=> 4-Hydroxyphenylglyoxylate + L-Glutamate
ATP + Deoxy-5-methylcytidylate <=> ADP + 5-Methyldeoxycytidine diphosphate
Propane-1,2-diol 1-phosphate + NAD+ <=> Hydroxyacetone phosphate + NADH + H+
S-Adenosyl-L-methionine + Magnesium protoporphyrin <=> S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester
N-Substituted aminoacyl-tRNA + H2O <=> N-Substituted amino acid + tRNA
Protein lysine + H2O + Oxygen <=> [Protein]-(S)-2-amino-6-oxohexanoate + Ammonia + Hydrogen peroxide
ATP + THF-polyglutamate(n) + L-Glutamate <=> ADP + Orthophosphate + THF-polyglutamate(n+1)
THF-polyglutamate + (n-1) H2O <=> Tetrahydrofolate + (n-1) L-Glutamate
CTP + 2-Aminoethylphosphonate <=> Diphosphate + CMP-2-aminoethylphosphonate
2-Aminoethylphosphonate + Hydrogen peroxide <=> Ethanolamine + Orthophosphate
2-Aminoethylphosphonate <=> (2-Amino-1-hydroxyethyl)phosphonate
2-Aminoethylphosphonate <=> N-Monomethyl-2-aminoethylphosphonate
Phosphonoacetaldehyde + NAD+ + H2O <=> Phosphonoacetate + NADH + H+
2-Aminoethylphosphonate <=> Ciliatocholate
n (R)-3-Hydroxybutanoyl-CoA <=> Poly-beta-hydroxybutyrate + n CoA
Leukotriene E4 + Oxygen + NADPH + H+ <=> 20-Hydroxyleukotriene E4 + NADP+ + H2O
Resveratrol <=> Piceatannol
4-Chlorocatechol + Oxygen <=> 3-Chloro-cis,cis-muconate
2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Chloro-cis,cis-muconate
2,5-Dihydro-5-oxofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate
7alpha-Hydroxycholesterol + NAD+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADH + H+
7alpha-Hydroxycholesterol + NADP+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADPH + H+
CDP-3,6-dideoxy-D-glucose + NADP+ <=> CDP-4-dehydro-3,6-dideoxy-D-glucose + NADPH + H+
CDP-3,6-dideoxy-D-glucose <=> CDP-3,6-dideoxy-D-mannose
ATP + Deoxynucleoside 5'-phosphate <=> ADP + 2'-Deoxyribonucleoside diphosphate
N-Formyl-L-methionylaminoacyl-tRNA + H2O <=> Formate + L-Methionylaminoacyl-tRNA
L-threo-3-Methylaspartate + 2-Oxoglutarate <=> Methyloxaloacetate + L-Glutamate
Methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside + H2O <=> 6-Deoxy-L-galactose + Methyl beta-D-galactoside
N-Hydroxy-4-acetylaminobiphenyl + N-Hydroxy-4-aminobiphenyl <=> N-Hydroxy-4-aminobiphenyl + N-Acetoxy-4-aminobiphenyl
Dolichyl diphosphooligosaccharide + H2O <=> Oligosaccharide phosphate + Dolichyl phosphate
Peptidylproline (omega=180) <=> Peptidylproline (omega=0)
ATP + RNA 3'-terminal-phosphate <=> AMP + Diphosphate + RNA terminal-2',3'-cyclic-phosphate
ATP + [Tyrosine-3-monoxygenase] <=> ADP + Phospho-[tyrosine-3-monoxygenase]
cis-3,4-Leucopelargonidin + 2-Oxoglutarate + Oxygen <=> Pelargonidin + Succinate + CO2 + 2 H2O
2-Pyrone-4,6-dicarboxylate + H2O <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
2-Hydroxy-2-hydropyrone-4,6-dicarboxylate + NAD+ <=> 2-Pyrone-4,6-dicarboxylate + NADH + H+
2-Hydroxy-2-hydropyrone-4,6-dicarboxylate + NADP+ <=> 2-Pyrone-4,6-dicarboxylate + NADPH + H+
3-O-Methylgallate + Oxygen <=> 2-Pyrone-4,6-dicarboxylate + Methanol
Carbamoyl phosphate + 3-Hydroxymethyl ceph-3-em-4-carboxylate <=> Orthophosphate + 3-Carbamoyloxymethylcephem
4-Imidazolone-5-propanoate + H2O <=> Formylisoglutamine
4-Imidazolone-5-propanoate + H2O <=> 4-Oxoglutaramate + Formate + Ammonia
6-Lactoyl-5,6,7,8-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+
7,8-Dihydroneopterin 3'-triphosphate <=> 6-Pyruvoyltetrahydropterin + Triphosphate
CMP-N-glycoloylneuraminate <=> Glycolipid
UDP-N-acetyl-alpha-D-glucosamine + Lysosomal-enzyme D-mannose <=> UMP + Lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose
Quinolinate + 2 H2O + Orthophosphate <=> Iminoaspartate + Glycerone phosphate
Quinolinate + H2O <=> 2-Amino-3-carboxymuconate semialdehyde
2'-Deoxyribonucleoside diphosphate + Thioredoxin disulfide + H2O <=> Ribonucleoside diphosphate + Thioredoxin
UDP-glucose + (S)-4-Hydroxymandelonitrile <=> UDP + Dhurrin
1,2,3,5-Tetrahydroxybenzene + 1,2,3-Trihydroxybenzene <=> 1,2,3,5-Tetrahydroxybenzene + Phloroglucinol
2-Amino-2-deoxy-D-gluconate <=> Aminosugar
Dopamine + H2O + Oxygen <=> 3,4-Dihydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide
S-Adenosyl-L-methionine + Dopamine <=> S-Adenosyl-L-homocysteine + 3-Methoxytyramine
para-(Dimethylamino)azobenzene + NADP+ + H2O <=> 4-(Dimethylamino)phenylazoxybenzene + NADPH + H+
4-Hydroxyphenylethanol + NAD+ <=> 4-Hydroxyphenylacetaldehyde + NADH + H+
4-Hydroxyphenylacetaldehyde + Dopamine <=> (S)-Norcoclaurine + H2O
(Z)-4-Hydroxyphenylacetaldehyde oxime <=> 4-Hydroxyphenylacetonitrile + H2O
trans-4-Hydroxycyclohexanecarboxylate + NAD+ <=> 4-Oxocyclohexanecarboxylate + NADH + H+
Etiocholanolone + NAD+ <=> 5beta-Androstane-3,17-dione + NADH + H+
Etiocholanolone + NADP+ <=> 5beta-Androstane-3,17-dione + NADPH + H+
Acylglycerone phosphate + Long-chain alcohol <=> O-Alkylglycerone phosphate + Long-chain acid anion
Diphosphate + Microsomal-membrane protein <=> Orthophosphate + O-Phospho-microsomal-membrane protein
N6,N6,N6-Trimethyl-L-lysine + 2 Protein <=> Protein N6,N6,N6-trimethyl-L-lysine + 2 H2O
DNA containing 6-O-methylguanine + [Protein]-L-cysteine <=> Protein S-methyl-L-cysteine + DNA containing guanine
Deoxynucleoside triphosphate + Thioredoxin disulfide + H2O <=> Ribonucleoside triphosphate + Thioredoxin
Acetyl-CoA + Ribosomal-protein L-alanine <=> CoA + Ribosomal-protein N-acetyl-L-alanine
S-Methyl-3-phospho-1-thio-D-glycerate + H2O <=> S-Methyl-1-thio-D-glycerate + Orthophosphate
Benzylpenicilloic acid <=> Penicillin G + H2O
trans-2,3-Dehydroacyl-CoA + NADP+ <=> (2E,4E)-2,4-Dienoyl-CoA + NADPH + H+
Pectate + H2O <=> Pectate + D-Galacturonate
CDP-choline + 1-Alkyl-2-acetyl-sn-glycerol <=> CMP + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine
UDP-alpha-D-galactose + 2-(2-Hydroxyacyl)sphingosine <=> UDP + 1-(beta-D-Galactosyl)-2-(2-hydroxyacyl)sphingosine
2-Amino-3-carboxymuconate semialdehyde <=> 2-Aminomuconate semialdehyde + CO2
10-Formyltetrahydrofolate + 5'-Phosphoribosylglycinamide <=> Tetrahydrofolate + 5'-Phosphoribosyl-N-formylglycinamide
5'-Phosphoribosylglycinamide + 5,10-Methenyltetrahydrofolate + H2O <=> 5'-Phosphoribosyl-N-formylglycinamide + Tetrahydrofolate
2 Juglone + Oxygen <=> 2 3,5-Dihydroxy-1,4-naphthoquinone
Lathosterol + CO2 + 4 H2O + 3 NADP+ <=> Methostenol + 3 Oxygen + 3 NADPH + 3 H+
Androstan-3alpha,17beta-diol + NAD+ <=> Dihydrotestosterone + NADH + H+
GDP-mannose + N,N'-Diacetylchitobiosyldiphosphodolichol <=> GDP + alpha-D-Mannosylchitobiosyldiphosphodolichol
S-Adenosyl-L-methionine + Glucuronoxylan D-glucuronate <=> S-Adenosyl-L-homocysteine + Glucuronoxylan 4-O-methyl-D-glucuronate
Indole-3-acetyl-beta-1-D-glucoside + myo-Inositol <=> D-Glucose + Indole-3-acetyl-myo-inositol
UDP-alpha-D-galactose + Indole-3-acetyl-myo-inositol <=> UDP + 5-O-(Indol-3-ylacetyl-myo-inositol) D-galactoside
UDP-L-arabinose + Indole-3-acetyl-myo-inositol <=> UDP + Indol-3-ylacetyl-myo-inositol L-arabinoside
L-2-Amino-6-oxoheptanedioate <=> 2,3,4,5-Tetrahydrodipicolinate + H2O
S-(4-Bromophenyl)-L-cysteine + 2-Oxoglutarate <=> 3-[(4-Bromophenyl)sulfanyl]-2-oxopropanoate + L-Glutamate
Thiomorpholine 3-carboxylate + NAD+ <=> 3,4-Dehydrothiomorpholine-3-carboxylate + NADH + H+
Thiomorpholine 3-carboxylate + NADP+ <=> 3,4-Dehydrothiomorpholine-3-carboxylate + NADPH + H+
alpha-N-Peptidyl-L-glutamine + H2O <=> alpha-N-Peptidyl-L-glutamate + Ammonia
p-Coumaroyl quinic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Chlorogenate + [Oxidized NADPH---hemoprotein reductase] + H2O
UDP-D-galacturonate + Pectate <=> UDP + Pectate
5alpha-Androstan-3beta,17beta-diol + NADP+ <=> Dihydrotestosterone + NADPH + H+
2,4-Dichloro-2,5-dihydro-5-oxofuran-2-acetate <=> 2,4-Dichloro-cis,cis-muconate
2,4-Dioxotetrahydropyrimidine D-ribonucleotide + Diphosphate <=> 5,6-Dihydrouracil + 5-Phospho-alpha-D-ribose 1-diphosphate
5-Methyl-5,6,7,8-tetrahydromethanopterin + Coenzyme M + 2 Sodium cation(side 1) <=> 5,6,7,8-Tetrahydromethanopterin + 2-(Methylthio)ethanesulfonate + 2 Sodium cation(side 2)
Acetyl-CoA + 2-Deoxystreptamine antibiotic <=> CoA + N3-Acetyl-2-deoxystreptamine antibiotic
Bromoxynil + 2 H2O <=> 3,5-Dibromo-4-hydroxybenzoate + Ammonia
L-Mimosine + H2O <=> 3-Hydroxy-4H-pyrid-4-one + L-Serine
Etiocholanolone + UDP-glucuronate <=> Etiocholan-3alpha-ol-17-one 3-glucuronide + UDP
2-Methoxyestrone + UDP-glucuronate <=> 2-Methoxyestrone 3-glucuronide + UDP
2-Methoxy-17beta-estradiol + UDP-glucuronate <=> 2-Methoxy-estradiol-17beta 3-glucuronide + UDP
Acetyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CO2 + Acyl-carrier protein
Malonyl-CoA + Flavonol 3-O-beta-D-glucoside <=> CoA + Flavonol 3-O-(6-O-malonyl-beta-D-glucoside)
ATP + [DNA-directed RNA polymerase] <=> ADP + Phospho-[DNA-directed RNA polymerase]
UDP-glucose + Sarsasapogenin <=> UDP + Asparagoside A
1-Alkyl-sn-glycero-3-phosphate + NADP+ <=> O-Alkylglycerone phosphate + NADPH + H+
Acyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-Acyl-1-alkyl-sn-glycero-3-phosphate
1-Alkyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-Alkyl-sn-glycero-3-phosphate + Ethanolamine
Acyl-CoA + 1-Alkyl-2-acetyl-sn-glycerol <=> CoA + 1-O-Alkyl-2-acetyl-3-acyl-sn-glycerol
2,3,4,5-Tetrahydrodipicolinate + Acetyl-CoA + H2O <=> N-Acetyl-L-2-amino-6-oxopimelate + CoA
Succinyl-CoA + 2,3,4,5-Tetrahydrodipicolinate + H2O <=> CoA + N-Succinyl-2-L-amino-6-oxoheptanedioate
Linalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (E)-3,7-Dimethylocta-1,6-diene-3,8-diol + [Oxidized NADPH---hemoprotein reductase] + H2O
4-Nitrophenyl-3-ketovalidamine <=> 4-Nitroaniline + 5-D-(5/6)-5-C-(Hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one
7-Methylguanosine 5'-triphospho-5'-oligonucleotide + H2O <=> 7-Methylguanosine 5'-phosphate + Oligonucleotide 5'-diphosphate
ATP + D-Alanine + Alanyl-poly(glycerolphosphate) <=> ADP + Orthophosphate + D-Alanyl-alanyl-poly(glycerolphosphate)
Benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP+ <=> Benzyl 2-methyl-3-oxobutanoate + NADPH + H+
Homoisocitrate <=> (Z)-But-1-ene-1,2,4-tricarboxylate + H2O
D-myo-Inositol 3,4-bisphosphate + H2O <=> 1D-myo-Inositol 3-phosphate + Orthophosphate
Glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O <=> N-Acetyl-D-glucosamine + Glycoprotein phospho-D-mannose
trans-3-Hydroxy-L-proline <=> 1-Pyrroline-2-carboxylate + H2O
2-Dehydro-3-deoxy-D-xylonate + NAD+ <=> 5-Hydroxy-2,4-dioxopentanoate + NADH
3-(2,3-Dihydroxyphenyl)propanoate + Oxygen <=> 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
3-D-Glucosyl-1,2-diacylglycerol + UDP-glucose <=> Diglucosyldiacylglycerol + UDP
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Diphosphate <=> 5-Amino-4-imidazolecarboxyamide + 5-Phospho-alpha-D-ribose 1-diphosphate
5-Carboxymethyl-2-hydroxymuconate <=> 5-Carboxy-2-oxohept-3-enedioate
5-Carboxy-2-oxohept-3-enedioate <=> 2-Hydroxyhepta-2,4-dienedioate + CO2
4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate <=> 2 5-Dehydro-4-deoxy-D-glucuronate
5-Dehydro-4-deoxy-D-glucuronate <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate
Methanol + Co(I) corrinoid protein <=> Methyl-Co(III) corrinoid protein + H2O
ATP + Holo-[carboxylase] + HCO3- <=> ADP + Orthophosphate + Carboxybiotin-carboxyl-carrier protein
Acetyl-CoA + Carboxybiotin-carboxyl-carrier protein <=> Malonyl-CoA + Holo-[carboxylase]
Diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ <=> Diethyl 2-methyl-3-oxosuccinate + NADPH + H+
ATP + Guanidinoethyl methyl phosphate <=> ADP + N'-Phosphoguanidinoethyl methyl phosphate
Heparosan-N-sulfate D-glucuronate <=> Heparosan-N-sulfate L-iduronate
alpha-Aminoadipoyl-S-acyl enzyme + NADPH + H+ <=> L-2-Aminoadipate 6-semialdehyde + Holo-Lys2 + NADP+
ATP + N-((R)-Pantothenoyl)-L-cysteine <=> ADP + (R)-4'-Phosphopantothenoyl-L-cysteine
Pregna-4,9(11)-diene-3,20-dione + Reduced acceptor + Oxygen <=> 9,11alpha-Epoxypregn-4-ene-3,20-dione + Acceptor + H2O
Protein N(pi)-phospho-L-histidine + Lactose <=> Protein histidine + Lactose 6'-phosphate
Protein N(pi)-phospho-L-histidine + Salicin <=> Protein histidine + Salicin 6-phosphate
S-Adenosyl-L-methionine + 1,4-alpha-D-Glucooligosaccharide <=> S-Adenosyl-L-homocysteine + Oligosaccharide containing 6-methyl-D-glucose units
2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + 2 H2O <=> Acetate + 2-(Hydroxymethyl)-4-oxobutanoate + Ammonia + CO2
S-Adenosyl-L-methionine + Gossypetin <=> S-Adenosyl-L-homocysteine + Corniculatusin
4-Carboxy-4-hydroxy-2-oxoadipate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate + H2O
Isocorypalmine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-Canadine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ATP + [Isocitrate dehydrogenase (NADP+)] <=> ADP + [Isocitrate dehydrogenase (NADP+)] phosphate
ATP + Low-density lipoprotein L-serine <=> ADP + Low-density lipoprotein O-phospho-L-serine
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 4-phosphate + Orthophosphate
5-Methyltetrahydropteroyltri-L-glutamate + L-Homocysteine <=> Tetrahydropteroyltri-L-glutamate + L-Methionine
trans-Cinnamoyl beta-D-glucoside + Methanol <=> Methyl cinnamate + D-Glucose
trans-Cinnamoyl beta-D-glucoside + Ethanol <=> Ethyl cinnamate + D-Glucose
trans-Cinnamoyl beta-D-glucoside + Alcohol <=> Alkyl cinnamate + D-Glucose
(6S,9R)-Vomifoliol + NAD+ <=> Dehydrovomifoliol + NADH + H+
Acyl-CoA + 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine <=> CoA + O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <=> cis-Dec-3-enoyl-[acp] + H2O
2-Hydroxy-5-carboxymethylmuconate semialdehyde + NAD+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADH + H+
2-Hydroxy-5-carboxymethylmuconate semialdehyde + NADP+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADPH + H+
S-Methyl-5-thio-D-ribose 1-phosphate <=> S-Methyl-5-thio-D-ribulose 1-phosphate
S-Adenosyl-L-methionine + N-Benzoyl-4-hydroxyanthranilate <=> S-Adenosyl-L-homocysteine + N-Benzoyl-4-methoxyanthranilate
alpha-D-Aldosyl beta-D-fructoside + D-Aldose <=> D-Aldose + alpha-D-Aldosyl beta-D-fructoside
UDP-N-acetyl-D-galactosamine + alpha-L-Fucosyl-1,2-beta-D-galactoside <=> UDP + N-Acetyl-alpha-D-galactosaminyl-(1,3)-[alpha-L-fucosyl-(1,2)]-D-galactoside
2-Methylcitrate <=> (Z)-But-2-ene-1,2,3-tricarboxylate + H2O
(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate <=> (Z)-But-2-ene-1,2,3-tricarboxylate + H2O
(2R,3S)-3-Isopropylmalate + NAD+ <=> (2S)-2-Isopropyl-3-oxosuccinate + NADH + H+
S-Adenosyl-L-methionine + Zymosterol <=> S-Adenosyl-L-homocysteine + Fecosterol
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] <=> But-2-enoyl-[acyl-carrier protein] + H2O
Butyryl-[acp] + NAD+ <=> But-2-enoyl-[acyl-carrier protein] + NADH + H+
Butyryl-[acp] + NADP+ <=> But-2-enoyl-[acyl-carrier protein] + NADPH + H+
UDP-alpha-D-galactose + D-Galactosyl-(1->4)-beta-D-glucosyl-R <=> UDP + D-Galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R
Electron-transferring flavoprotein + Propanoyl-CoA <=> Reduced electron-transferring flavoprotein + Propenoyl-CoA
Reduced electron-transferring flavoprotein + Ubiquinone <=> Electron-transferring flavoprotein + Ubiquinol
N-Acetylneuraminate 9-phosphate + Orthophosphate <=> N-Acetyl-D-mannosamine 6-phosphate + Phosphoenolpyruvate + H2O
S-Adenosyl-L-methionine + N,N-Dimethylhistidine <=> S-Adenosyl-L-homocysteine + Hercynine
[eIF5A-precursor]-deoxyhypusine + Reduced acceptor + Oxygen <=> Protein N6-[(R)-4-amino-2-hydroxybutyl]-L-lysine + Acceptor + H2O
dTDP-4-amino-4,6-dideoxy-D-galactose + 2-Oxoglutarate <=> dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate
(R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Acetolactate + NADPH + H+
(R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid + NADPH + H+
(R)-2,3-Dihydroxy-3-methylbutanoate <=> 3-Methyl-2-oxobutanoic acid + H2O
L-1-Pyrroline-3-hydroxy-5-carboxylate + H2O <=> L-4-Hydroxyglutamate semialdehyde
L-1-Pyrroline-3-hydroxy-5-carboxylate + NAD+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADH + H+
L-1-Pyrroline-3-hydroxy-5-carboxylate + NADP+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADPH + H+
1-Pyrroline-4-hydroxy-2-carboxylate + H2O <=> 2-Oxo-4-hydroxy-5-aminovalerate
1-Pyrroline-4-hydroxy-2-carboxylate <=> Pyrrole-2-carboxylate + H2O
ATP + 5-(2-Hydroxyethyl)-4-methylthiazole <=> ADP + 4-Methyl-5-(2-phosphooxyethyl)thiazole
ATP + Acetate + Holo-[citrate (pro-3S)-lyase] <=> AMP + Diphosphate + Acetyl-[citrate (pro-3S)-lyase]
Acetyl-[citrate (pro-3S)-lyase] + H2O <=> Holo-[citrate (pro-3S)-lyase] + Acetate
UDP-N-acetyl-alpha-D-glucosamine + Estradiol-17alpha 3-D-glucuronoside <=> UDP + 17alpha-(N-Acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Acetate
4-Carboxy-2-hydroxymuconate semialdehyde + NADP+ + H2O <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate + NADPH + H+
5,10-Methenyltetrahydromethanopterin + Hydrogen <=> 5,10-Methylenetetrahydromethanopterin + H+
5,10-Methylenetetrahydromethanopterin + Coenzyme F420 + H+ <=> 5,10-Methenyltetrahydromethanopterin + Reduced coenzyme F420
5-Amino-6-(1-D-ribitylamino)uracil + L-3,4-Dihydroxybutan-2-one 4-phosphate <=> 6,7-Dimethyl-8-(D-ribityl)lumazine + 2 H2O + Orthophosphate
6,7-Dimethyl-8-(D-ribityl)lumazine <=> 7-Hydroxy-6-methyl-8-ribityllumazine
Variant-surface-glycoprotein 1,2-dimyristyl-sn-phosphatidylinositol <=> Soluble variant-surface-glycoprotein + 1,2-Dimyristyl-sn-glycerol
N-Hydroxy-L-tyrosine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-tyrosine + [Oxidized NADPH---hemoprotein reductase] + H2O
1,2-Bis(3,4-dimethoxyphenyl)propane-1,3-diol + Hydrogen peroxide <=> Veratraldehyde + 1-(3,4-Dimethoxyphenyl)ethane-1,2-diol + H2O
ATP + 5'-Phosphoribosyl-N-formylglycinamide + L-Glutamine + H2O <=> ADP + Orthophosphate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine + L-Glutamate
5,10-Methylenetetrahydromethanopterin + Reduced coenzyme F420 <=> 5-Methyl-5,6,7,8-tetrahydromethanopterin + Coenzyme F420
Acetyl-CoA + Heparan sulfate alpha-D-glucosaminide <=> CoA + Heparan sulfate N-acetyl-alpha-D-glucosaminide
N6-Acetyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Acetyl-L-2-amino-6-oxopimelate + L-Glutamate
1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-alpha-D-galactose <=> Digalactosyl-diacylglycerol + UDP
Digalactosyl-diacylglycerol + H2O <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + D-Galactose
3-beta-D-Galactosyl-sn-glycerol + 2 Fatty acid <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O
2 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> 1,2-Diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 1,2-Diacyl-sn-glycerol
Acyl-[acyl-carrier protein] + 2-Acyl-3-O-(beta-D-galactosyl)-sn-glycerol <=> Acyl-carrier protein + 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol
2 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> 2-Acyl-3-O-(beta-D-galactosyl)-sn-glycerol + Acyl1-monogalactosyl-diacylglycerol
N-Succinyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Succinyl-2-L-amino-6-oxoheptanedioate + L-Glutamate
3'-Phosphoadenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate <=> Adenosine 3',5'-bisphosphate + UDP-N-acetyl-D-galactosamine 4,6-bissulfate
UDP-N-acetyl-D-mannosaminouronate + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> N-Acetyl-beta-D-mannosaminuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP
4-Carboxy-4-hydroxy-2-oxoadipate <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate + H2O
1-(5-Phosphoribosyl)imidazole-4-acetate + H2O <=> (1-Ribosylimidazole)-4-acetate + Orthophosphate
Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA
S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine
4-Carboxy-2-oxo-3-hexenedioate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NAD+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + CO2 + NADH + H+
Acetyl-CoA + alpha-2,8-Linked polymer of sialic acid <=> CoA + Polysialic acid acetylated at O-7
Glycodeoxycholate + H2O <=> Deoxycholic acid + Glycine
Taurodeoxycholate + H2O <=> Deoxycholic acid + Taurine
4-Carboxy-2-hydroxymuconate semialdehyde + H2O <=> 4-Methylene-2-oxoglutarate + Formate
2-Hydroxy-2-hydropyrone-4,6-dicarboxylate <=> 4-Carboxy-2-hydroxymuconate semialdehyde
5-(4-Acetoxybut-1-ynyl)-2,2'-bithiophene + H2O <=> 5-(4-Hydroxybut-1-ynyl)-2,2'-bithiophene + Acetate
UDP-glucose + 5-(D-Galactosyloxy)-L-lysine-procollagen <=> UDP + 1,2-D-Glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen
UDP-N-acetyl-alpha-D-glucosamine + Lactosylceramide <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-D-glucosaminyldiphosphodolichol <=> UDP + N,N'-Diacetylchitobiosyldiphosphodolichol
UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-glycopeptide <=> UDP + beta-D-Galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide
S-Adenosyl-L-methionine + Protein C-terminal S-farnesyl-L-cysteine <=> S-Adenosyl-L-homocysteine + Protein C-terminal S-farnesyl-L-cysteine methyl ester
1-O-Galloyl-beta-D-glucose + 1,2,3,6-Tetrakis-O-galloyl-beta-D-glucose <=> D-Glucose + Pentagalloylglucose
2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <=> cis-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid
4,4-Dimethyl-5alpha-cholest-7-en-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-Hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Ferricytochrome b5 + H2O
GDP-mannose + N,N'-Diacetylchitobiosyldiphosphodolichol <=> GDP + beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol
Protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine + H2O <=> D-Glucose + Protein beta-D-galactosyl-L-hydroxylysine
1-Phosphatidyl-1D-myo-inositol 3-phosphate + 2 ATP <=> Phosphatidylinositol-3,4,5-trisphosphate + 2 ADP
S-Adenosyl-L-methionine + Tomentin <=> S-Adenosyl-L-homocysteine + Chrysosplenol D + H+
3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + NAD+ + H2O <=> 3alpha,7alpha-Dihydroxy-5beta-cholestanate + NADH + H+
ATP + 3alpha,7alpha-Dihydroxy-5beta-cholestanate + CoA <=> AMP + Diphosphate + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
ATP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine <=> ADP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate
4-Methylmuconolactone <=> 3-Methylmuconolactone
Phosphatidylglycerol + Membrane-derived-oligosaccharide D-glucose <=> 1,2-Diacyl-sn-glycerol + Membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose
3-D-Glucuronosyl-N2,6-disulfo-beta-D-glucosamine + H2O <=> N,6-O-Disulfo-D-glucosamine + D-Glucuronate
Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + Orthophosphate
Phosphatidylcholine + Retinol-(cellular-retinol-binding-protein) <=> 2-Acyl-sn-glycero-3-phosphocholine + Retinyl-ester-(cellular-retinol-binding-protein)
(4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + H2O <=> L-Xylonate + CO2
(15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NAD+ <=> 15-OxoETE + NADH + H+
(15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NADP+ <=> 15-OxoETE + NADPH + H+
Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-g-D-Glu-A2pm-D-Ala-D-Ala)]n-diphosphoundecaprenol <=> di-trans,poly-cis-Undecaprenyl diphosphate + [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-g-D-Glu-A2pm-D-Ala-D-Ala)]n-diphosphoundecaprenol
Geranylgeranyl diphosphate + 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate <=> Diphosphate + 2,3-Bis-O-(geranylgeranyl)glycerol 1-phosphate
DDT <=> 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + Hydrochloric acid
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + Oxygen <=> 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide + NADP+ + H2O
3-Hydroxy-2-methylpyridine-4,5-dicarboxylate + NADH + H+ <=> 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate + H2O + NAD+
5-(3,4-Diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O <=> 5-(3-Hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + Acetate
UDP-apiose + Apigenin 7-O-beta-D-glucoside <=> UDP + Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]
Peptide beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-L-serine + H2O <=> beta-D-Galactosyl-(1->3)-N-acetyl-D-galactosamine + [Protein]-L-serine
UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + 2-Oxoglutarate <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-Glutamate
UDP-alpha-D-galactose + N-Acetyllactosamine <=> UDP + alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosamine
CMP-N-acetylneuraminate + N-Acetyllactosamine <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=> Acetoacetyl-[acp] + NADPH + H+
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxodecanoyl-[acp] + NADPH
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <=> trans-Dec-2-enoyl-[acp] + H2O
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxooctanoyl-[acp] + NADPH + H+
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] <=> trans-Oct-2-enoyl-[acp] + H2O
(E)-2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide <=> (Z)-2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide
Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Dihydromethanophenazine <=> Coenzyme B + Coenzyme M + Methanophenazine
Coenzyme B + 2-(Methylthio)ethanesulfonate <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Methane
[Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O <=> [Hydroxymethylglutaryl-CoA reductase (NADPH)] + Orthophosphate
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexadecanoyl-[acp] + NADPH + H+
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] <=> trans-Hexadec-2-enoyl-[acp] + H2O
ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate
Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + FAD <=> (24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + FADH2
UDP-alpha-D-galactose + alpha-L-Fucosyl-1,2-beta-D-galactoside <=> UDP + alpha-D-Galactosyl-(1,3)-[alpha-L-fucosyl-(1,2)]-D-galactoside
UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + H2O <=> UMP + Lipid X
UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <=> UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + Acyl-carrier protein
Alprostadil + NADP+ <=> (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+
GDP-L-fucose + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-R <=> GDP + 1,3-beta-D-Galactosyl-(alpha-1,4-L-fucosyl)-N-acetyl-D-glucosaminyl-R
ATP + [Hydroxymethylglutaryl-CoA reductase (NADPH)] <=> ADP + [Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate
(5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoate + NAD+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADH + H+
(5Z)-(15S)-11alpha-Hydroxy-9,15-dioxoprostanoate + NADP+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+
N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + L-Glutamine <=> D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + L-Glutamate
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <=> Fumarate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
ATP + Biotin + Apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [Acetyl-CoA:carbon-dioxide ligase (ADP-forming)]
ATP + Biotin + Apo-[methylmalonyl-CoA:pyruvate carboxytransferase] <=> AMP + Diphosphate + [Methylmalonyl-CoA:pyruvate carboxytransferase]
CMP-N-acetylneuraminate + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R
(13E)-(15S)-15-Hydroxy-9-oxoprosta-10,13-dienoate <=> (13E)-(15S)-15-Hydroxy-9-oxoprosta-11,13-dienoate
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxotetradecanoyl-[acp] + NADPH + H+
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetyl-alpha-D-glucosamine <=> Acyl-carrier protein + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <=> trans-Tetradec-2-enoyl-[acp] + H2O
3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + Oxygen + NADPH + H+ <=> 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + NADP+
1-Alkyl-2-acylglycerophosphoethanolamine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Ferricytochrome b5 + 2 H2O
ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> UDP + beta-D-Galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R
cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide <=> trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide
UDP-glucose + Nuatigenin <=> UDP + (20S,22S,25S)-22,25-Epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucoside
1,6,6-Trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one <=> 4,5-Dihydro-5,5-dimethyl-4-(3-oxobutyl)furan-2(3H)-one
UDP-glucose + DIMBOA <=> UDP + DIMBOA-glucoside
ATP + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + CoA <=> AMP + Diphosphate + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA
CDP-abequose + D-Mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid <=> CDP + D-Abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid
ATP + Biotin + Apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [Propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
CMP-N-acetylneuraminate + GM3 <=> CMP + GD3
UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> GM3 + N-Acetyl-D-galactosamine
UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O <=> UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + Acetate
S-Acetylphosphopantetheine + Holo-[citrate (pro-3S)-lyase] <=> Pantetheine 4'-phosphate + Acetyl-[citrate (pro-3S)-lyase]
ATP + Dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)]kinase] <=> ADP + [[Hydroxymethylglutaryl-CoA reductase (NADPH)]kinase]
CMP-N-acetylneuraminate + beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R
ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA + FAD <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + FADH2
3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate <=> 5-Pyridoxolactone + H2O
N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H2O <=> alpha-Ribazole + Orthophosphate
CMP-N-acetylneuraminate + beta-D-Galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein
3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + Oxygen <=> 3-Hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate
Stizolobate + NADH + H+ <=> 4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NAD+
Stizolobate + NADPH + H+ <=> 4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+
Stizolobinate + NADH + H+ <=> 5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NAD+
Stizolobinate + NADPH + H+ <=> 5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+
5-Amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone + Oxygen <=> 5-Amino-4-chloro-2-(5-hydroxymuconoyl)-3(2H)-pyridazinone
UDP-N-acetyl-D-galactosamine + D-Glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan <=> UDP + N-Acetyl-beta-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan
ATP + Biotin + Apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)]
UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + Lipid X <=> UDP + Lipid A disaccharide
UDP-glucuronate + 3-beta-D-Galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein <=> UDP + 3-beta-D-Glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein
Juvenile hormone II + H2O <=> Juvenile hormone II acid + Methanol
(5Z,9E,14Z)-(8xi,11R,12S)-11,12-Epoxy-8-hydroxyicosa-5,9,14-trienoic acid + H2O <=> (5Z,9E,14Z)-(8xi,11xi,12S)-8,11,12-Trihydroxyicosa-5,9,14-trienoate
UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide
UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + H2O <=> UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanine + D-Alanine
UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + L-Alanyl-tRNA <=> UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA(Ala)
UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + N-Acetyl-D-galactosaminyl-1,4-beta-N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide
20-OH-Leukotriene B4 <=> 20-COOH-Leukotriene B4
ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine
Malonyl-CoA + Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside] <=> CoA + Malonylapiin
UDP-N-acetyl-alpha-D-glucosamine + 1,3-alpha-D-Mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose <=> UDP + 1,3-alpha-D-Mannosyl-(1,2-N-acetyl-alpha-D-glucosaminyl)-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose
7,8-Dihydroneopterin 3'-triphosphate + 3 H2O <=> 7,8-Dihydroneopterin + 3 Orthophosphate
7,8-Dihydroneopterin + Orthophosphate <=> Dihydroneopterin phosphate + H2O
7,8-Dihydroneopterin + Acceptor <=> Neopterin + Reduced acceptor
(+/-)-5-[(tert-Butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+ <=> (+/-)-5-[(tert-Butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH + H+
CMP-N-acetylneuraminate + GA2 <=> CMP + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
UDP-alpha-D-galactose + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> UDP + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
CMP-N-acetylneuraminate + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GD2
D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + D-Galactose
N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> GA2 + N-Acetylneuraminate
CMP-N-acetylneuraminate + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactose-1,3-(alpha-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R
7,8-Dihydroneopterin 3'-triphosphate + H2O <=> Dihydroneopterin phosphate + Diphosphate
7,8-Dihydroneopterin 3'-triphosphate + H2O <=> 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine
5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide <=> N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide
1-(4-Amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O <=> 1-(4-Hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + Ammonia
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2)-(N-acetyl-beta-D-glucosaminyl-1,4)-alpha-D-mannosyl-R
3'-Phosphoadenylyl sulfate + alpha-D-Glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol <=> Adenosine 3',5'-bisphosphate + 6-Sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol
1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + UDP-alpha-D-galactose <=> Ceramidepentasaccharide + UDP
1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + UDP-N-acetyl-D-galactosamine <=> Ceramidepentasaccharide + UDP
1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + GDP-L-fucose <=> Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + GDP
CMP-N-acetylneuraminate + GA1 <=> CMP + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GD1b
D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + N-Acetylneuraminate <=> N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O
UDP-N-acetyl-alpha-D-glucosamine + alpha-D-Mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
CMP-N-acetylneuraminate + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide
ATP + Lipid A disaccharide <=> ADP + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate + CMP-3-deoxy-D-manno-octulosonate <=> 3-Deoxy-D-manno-octulosonyl-lipid IV(A) + CMP
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
CMP-N-acetylneuraminate + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GT1a
CMP-N-acetylneuraminate + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GT1b
UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2 <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-beta-D-mannosyl-R
UDP-N-acetyl-alpha-D-glucosamine + 6-(2-[N-Acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R <=> UDP + 6-(2,6-Bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
(R)-3-Ureidoisobutyrate + H2O <=> (R)-3-Amino-2-methylpropanoate + CO2 + Ammonia
7-Dehydrodesmosterol + Reduced acceptor <=> 5alpha-Cholesta-7,24-dien-3beta-ol + Acceptor
24,25-Dihydrolanosterol + NADPH <=> 4alpha-Methylcholesta-8-en-3beta-ol + NADP+
4alpha-Methylcholesta-8-en-3beta-ol <=> Methostenol
(S)-2-Acetolactate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + Pyruvate
2-Oxobutanoate + 2-(alpha-Hydroxyethyl)thiamine diphosphate <=> (S)-2-Aceto-2-hydroxybutanoate + Thiamin diphosphate
N-Methylhistamine + H2O + Oxygen <=> Methylimidazole acetaldehyde + Ammonia + Hydrogen peroxide
17alpha-Hydroxypregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha,21-Dihydroxypregnenolone + [Oxidized NADPH---hemoprotein reductase] + H2O
17alpha,20alpha-Dihydroxycholesterol + 2 Oxygen + 4 H+ + 4 Reduced adrenal ferredoxin <=> 17alpha-Hydroxypregnenolone + 4-Methylpentanal + 3 H2O + 4 Oxidized adrenal ferredoxin
16alpha-Hydroxyandrost-4-ene-3,17-dione + H+ + NADH <=> 16alpha-Hydroxydehydroepiandrosterone + NAD+
Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H+
Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+
UDP-glucuronate + Estriol <=> UDP + 16-Glucuronide-estriol
Aminoacyl-tRNA + Phosphatidylglycerol <=> Aminoacyl-phosphatidylglycerol + tRNA
Aminoacyl-tRNA + Peptidyl-tRNA <=> tRNA + Peptidyl-aminoacyl-tRNA
trans-beta-D-Glucosyl-2-hydroxycinnamate <=> cis-beta-D-Glucosyl-2-hydroxycinnamate
(2R,5S)-2,5-Diaminohexanoate + H2O + NAD+ <=> 2-Amino-5-oxohexanoate + Ammonia + NADH + H+
(2R,5S)-2,5-Diaminohexanoate + H2O + NADP+ <=> 2-Amino-5-oxohexanoate + Ammonia + NADPH + H+
(S)-Cheilanthifoline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Stylopine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Stylopine + S-Adenosyl-L-methionine <=> (S)-cis-N-Methylstylopine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + (S)-Coclaurine <=> S-Adenosyl-L-homocysteine + (S)-N-Methylcoclaurine + H+
(S)-N-Methylcoclaurine + Oxygen + Reduced acceptor <=> 3'-Hydroxy-N-methyl-(S)-coclaurine + H2O + Acceptor
(S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Berbamunine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(R)-Reticuline + NADP+ <=> 1,2-Dehydroreticuline + NADPH
(R)-Reticuline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Salutaridine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Salutaridinol + NADP+ <=> Salutaridine + NADPH + H+
Protopine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxyprotopine + [Oxidized NADPH---hemoprotein reductase] + H2O
Protopine + [Oxidized NADPH---hemoprotein reductase] + H2O <=> (S)-cis-N-Methylstylopine + [Reduced NADPH---hemoprotein reductase] + Oxygen
6-Hydroxyprotopine <=> Dihydrosanguinarine + 2 H2O
Dihydrosanguinarine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 10-Hydroxydihydrosanguinarine + [Oxidized NADPH---hemoprotein reductase] + H2O
Dihydrosanguinarine + Oxygen + H+ <=> Sanguinarine + Hydrogen peroxide
S-Adenosyl-L-methionine + 12-Hydroxydihydrochelirubine <=> S-Adenosyl-L-homocysteine + Dihydromacarpine + H+
Dihydrochelirubine + Oxygen + H+ <=> Chelirubine + Hydrogen peroxide
S-Adenosyl-L-methionine + 10-Hydroxydihydrosanguinarine <=> S-Adenosyl-L-homocysteine + Dihydrochelirubine + H+
Dihydrochelirubine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Hydroxydihydrochelirubine + [Oxidized NADPH---hemoprotein reductase] + H2O
3 Malonyl-CoA + 3-Hydroxybenzoyl-CoA <=> 4 CoA + 2,3',4,6-Tetrahydroxybenzophenone + 3 CO2
S-Adenosyl-L-methionine + Dihydroflavodoxin + Protein glycine <=> 5'-Deoxyadenosine + L-Methionine + Flavodoxin semiquinone + Protein glycin-2-yl radical
S-Adenosyl-L-methionine + 3-Hexaprenyl-4,5-dihydroxybenzoate <=> S-Adenosyl-L-homocysteine + 3-Hexaprenyl-4-hydroxy-5-methoxybenzoate + H+
S-Adenosyl-L-methionine + (R,S)-Tetrahydrobenzylisoquinoline <=> S-Adenosyl-L-homocysteine + N-Methyl-(R,S)-tetrahydrobenzylisoquinoline + H+
S-Adenosyl-L-methionine + 6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + Nororientaline + H+
S-Adenosyl-L-methionine + Tetrahydropapaveroline <=> S-Adenosyl-L-homocysteine + 6-O-Methylnorlaudanosoline + H+
S-Adenosyl-L-methionine + (S)-Tetrahydroprotoberberine <=> S-Adenosyl-L-homocysteine + cis-N-Methyl-(S)-7,8,13,14-tetrahydroprotoberberine
S-Adenosyl-L-methionine + [Cytochrome c] methionine <=> S-Adenosyl-L-homocysteine + [Cytochrome c] S-methylmethionine
S-Adenosyl-L-methionine + Histone L-arginine <=> S-Adenosyl-L-homocysteine + Histone N(omega)-methyl-L-arginine
S-Adenosyl-L-methionine + [Myeline basic protein] L-arginine <=> S-Adenosyl-L-homocysteine + [Myeline basic protein] N(omega)-methyl-L-arginine
1-Alkyl-2-arachidonyl-sn-glycero-3-phosphocholine + 1-Alkyl-2-lyso-sn-glycero-3-phosphoethanolamine <=> 1-Alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine
1-Radyl-2-acyl-sn-glycero-3-phosphocholine + 1-Alkyl-2-lyso-sn-glycero-3-phosphoethanolamine <=> 1-Alkyl-2-acylglycerophosphoethanolamine + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine
2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine + 1-Organyl-2-lyso-sn-glycero-3-phospholipid <=> 1-Radyl-2-acetyl-sn-glycero-3-phospholipid + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine
Acetyl-CoA + Salutaridinol <=> CoA + 7-O-Acetylsalutaridinol
Dodecanoyl-[acyl-carrier protein] + NAD+ <=> trans-Dodec-2-enoyl-[acp] + NADH + H+
Dodecanoyl-[acyl-carrier protein] + NADP+ <=> trans-Dodec-2-enoyl-[acp] + NADPH + H+
Dodecanoyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> 3-Oxotetradecanoyl-[acp] + CO2 + Acyl-carrier protein
N-Acetylarylalkylamine + H2O <=> Arylalkylamine + Acetate
Phaseollidin hydrate <=> Phaseollidin + H2O
(2S)-2-Methylacyl-CoA <=> (2R)-2-Methylacyl-CoA
ATP + Detyrosinated alpha-tubulin + L-Tyrosine <=> alpha-Tubulin + ADP + Orthophosphate
5-Aminoimidazole + H2O <=> Imidazolone + Ammonia
5-Aminoimidazole + CO2 <=> 5-Amino-4-imidazole carboxylate
UTP + [Protein-PII] <=> Diphosphate + Uridylyl-[protein-PII]
4a-Hydroxytetrahydrobiopterin <=> Dihydrobiopterin + H2O
L-Lysine 1,6-lactam <=> D-2-Aminohexano-6-lactam
(S)-3-Hydroxyhexadecanoyl-CoA + NAD+ <=> 3-Oxopalmitoyl-CoA + NADH + H+
(S)-3-Hydroxyhexadecanoyl-CoA <=> trans-Hexadec-2-enoyl-CoA + H2O
(S)-3-Hydroxytetradecanoyl-CoA + NAD+ <=> 3-Oxotetradecanoyl-CoA + NADH
(S)-3-Hydroxytetradecanoyl-CoA <=> trans-Tetradec-2-enoyl-CoA + H2O
(S)-3-Hydroxydodecanoyl-CoA + NAD+ <=> 3-Oxododecanoyl-CoA + NADH + H+
Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA
(S)-Hydroxydecanoyl-CoA + NAD+ <=> 3-Oxodecanoyl-CoA + NADH + H+
(S)-Hydroxydecanoyl-CoA <=> trans-Dec-2-enoyl-CoA + H2O
(S)-3-Hydroxyoctanoyl-CoA + NAD+ <=> 3-Oxooctanoyl-CoA + NADH + H+
(S)-3-Hydroxyoctanoyl-CoA <=> trans-Oct-2-enoyl-CoA + H2O
Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA
(S)-Hydroxyhexanoyl-CoA + NAD+ <=> 3-Oxohexanoyl-CoA + NADH + H+
(S)-Hydroxyhexanoyl-CoA <=> trans-Hex-2-enoyl-CoA + H2O
Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
Decanoyl-CoA + NADP+ <=> trans-Dec-2-enoyl-CoA + NADPH + H+
Decanoyl-CoA + FAD <=> trans-Dec-2-enoyl-CoA + FADH2
cis,cis-3,6-Dodecadienoyl-CoA <=> trans,cis-Lauro-2,6-dienoyl-CoA
11beta-Hydroxyandrost-4-ene-3,17-dione + NADP+ <=> Adrenosterone + NADPH + H+
19-Hydroxyandrost-4-ene-3,17-dione + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Oxoandrost-4-ene-3,17-dione + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
7alpha-Hydroxytestosterone + Acceptor <=> 7alpha-Hydroxyandrost-4-ene-3,17-dione + Reduced acceptor
19-Hydroxytestosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Oxotestosterone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
2-Hydroxyestrone + S-Adenosyl-L-methionine <=> 2-Methoxyestrone + S-Adenosyl-L-homocysteine
Desmosterol + S-Adenosyl-L-methionine <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + S-Adenosyl-L-homocysteine
2-Hydroxyestradiol + S-Adenosyl-L-methionine <=> 2-Methoxy-17beta-estradiol + S-Adenosyl-L-homocysteine
Dihydromacarpine + Oxygen + H+ <=> Macarpine + Hydrogen peroxide
7-O-Acetylsalutaridinol <=> Thebaine + Acetate
L-Selenomethionine + H2O <=> Methaneselenol + Ammonia + 2-Oxobutanoate
ATP + L-Selenomethionine + H2O <=> Orthophosphate + Diphosphate + Se-Adenosylselenomethionine
S-Adenosyl-L-methionine + L-Selenomethionine <=> S-Adenosyl-L-homocysteine + Se-Methylselenomethionine
ATP + L-Selenomethionine + tRNA(Met) <=> AMP + Diphosphate + Selenomethionyl-tRNA(Met)
L-Selenomethionine <=> Selenohomocysteine + Activated methyl group
L-Selenomethionine <=> Selenomethionine Se-oxide
L-Glutamate + 4-Hydroxyphenylacetyl-CoA <=> CoA + 4-Hydroxyphenylacetylglutamic acid
4-Hydroxyphenylacetyl-CoA + Glycine <=> p-Hydroxyphenylacetylglycine + CoA
ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate
beta-D-Fructose 1,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate
4-Carboxy-4-hydroxy-2-oxoadipate <=> 4-Carboxy-2-oxo-3-hexenedioate + H2O
Diimine + 2 e- + 2 H+ <=> Hydrazine
3-Ketolactose + H2O <=> 3-Keto-beta-D-galactose + beta-D-Glucose
(4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + H2O <=> L-Lyxonate + CO2
Dehydroascorbate + H2O <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
all-trans-Phytoene + Acceptor <=> all-trans-Phytofluene + Reduced acceptor
all-trans-Phytofluene + Acceptor <=> all-trans-zeta-Carotene + Reduced acceptor
5-Cholestene + Oxygen + NADPH + H+ <=> 5,6beta-Epoxy-5beta-cholestane + NADP+ + H2O
5-Cholestene + NADPH + Oxygen + H+ <=> 5,6alpha-Epoxy-5alpha-cholestane + NADP+ + H2O
5,6beta-Epoxy-5beta-cholestane + H2O <=> 5alpha-Cholestan-5alpha,6beta-diol
Cholesterol-5beta,6beta-epoxide + H2O <=> 3beta,5alpha,6beta-Cholestanetriol
5,6alpha-Epoxy-5alpha-cholestane + H2O <=> 5alpha-Cholestan-5alpha,6beta-diol
Phytyl diphosphate + Chlorophyllide <=> Bacteriopheophytin + Magnesium cation + Diphosphate
all-trans-zeta-Carotene + Reduced acceptor + Oxygen <=> all-trans-Neurosporene + 2 H2O + Acceptor
all-trans-zeta-Carotene + 2 Oxygen + 2 Reduced acceptor <=> Lycopene + 4 H2O + 2 Acceptor
all-trans-Neurosporene + Reduced acceptor + Oxygen <=> Lycopene + Acceptor + 2 H2O
all-trans-Neurosporene <=> beta-Zeacarotene
beta-Zeacarotene + Oxygen + Reduced acceptor <=> gamma-Carotene + 2 H2O + Acceptor
Zymosterol <=> 5alpha-Cholesta-7,24-dien-3beta-ol
3alpha,7alpha,26-Trihydroxy-5beta-cholestane + NAD+ <=> 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + NADH + H+
3alpha,7alpha-Dihydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + H2O + 2 Oxidized adrenal ferredoxin
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane + H2O + 2 Oxidized adrenal ferredoxin
3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane <=> 5beta-Cyprinolsulfate
(24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + H2O <=> (24R,25R)-3alpha,7alpha,24-Trihydroxy-5beta-cholestanoyl-CoA
(24R,25R)-3alpha,7alpha,24-Trihydroxy-5beta-cholestanoyl-CoA + NAD+ <=> 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA + NADH + H+
Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA
(24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA + NAD+ <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA + NADH + H+
(24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + H2O
7alpha-Hydroxy-5beta-cholestan-3-one + NADP+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADPH + H+
3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ <=> 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+
3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ <=> 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+
7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADP+ <=> 4-Cholesten-7alpha,12alpha-diol-3-one + NADPH + H+
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + NAD+ <=> 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADH + H+
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + NADP+ <=> 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADPH + H+
7alpha-Hydroxycholest-4-en-3-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Cholesten-7alpha,12alpha-diol-3-one + [Oxidized NADPH---hemoprotein reductase] + H2O
4-Cholesten-7alpha,12alpha-diol-3-one + Reduced acceptor <=> 7alpha,12alpha-Dihydroxy-5alpha-cholestan-3-one + Acceptor
Tetrahydrocortisone + NAD+ <=> 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADH + H+
17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + H+ + NADPH <=> Tetrahydrocortisone + NADP+
Cortolone + NAD+ <=> Tetrahydrocortisone + NADH + H+
Urocortisol + NAD+ <=> 11beta,17alpha,21-Trihydroxy-5beta-pregnane-3,20-dione + NADH + H+
Urocortisol + NADP+ <=> 11beta,17alpha,21-Trihydroxy-5beta-pregnane-3,20-dione + NADPH + H+
Cortol + NAD+ <=> Urocortisol + NADH + H+
3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al + NAD+ <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADH + H+
3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al + NADP+ <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADPH + H+
Tetrahydrocorticosterone + NAD+ <=> 11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADH + H+
Tetrahydrocorticosterone + NADP+ <=> 11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADPH + H+
Tetrahydrocorticosterone + NADP+ <=> 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADPH + H+
3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NAD+ <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione + NADH + H+
3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADP+ <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione + NADPH + H+
3alpha,20alpha,21-Trihydroxy-5beta-pregnan-11-one + NAD+ <=> 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADH + H+
Pregnanolone + NAD+ <=> 5beta-Pregnane-3,20-dione + NADH + H+
Pregnanolone + NADP+ <=> 5beta-Pregnane-3,20-dione + NADPH + H+
Pregnanediol + NAD+ <=> Pregnanolone + NADH + H+
11-Deoxycortisol + H+ + NADH <=> 17alpha,21-Dihydroxypregnenolone + NAD+
17alpha,21-Dihydroxypregnenolone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 11beta,17alpha,21-Trihydroxypregnenolone + 2 Oxidized ferredoxin + H2O
21-Deoxycortisol + [Oxidized NADPH---hemoprotein reductase] + H2O <=> 11beta-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen
20alpha-Hydroxycholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha,20alpha-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
20alpha-Hydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 20alpha,22beta-Dihydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
22(R)-Hydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 20alpha,22beta-Dihydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
Sulfatide + H2O <=> Galactosylceramide + Sulfate
5-Ureido-4-imidazole carboxylate + H2O <=> 5-Amino-4-imidazole carboxylate + Ammonia + CO2
S-Adenosyl-L-methionine + DNA cytosine <=> S-Adenosyl-L-homocysteine + DNA 5-methylcytosine
O-Acetyl-L-serine + Thiosulfate + Thioredoxin + H+ <=> L-Cysteine + Sulfite + Thioredoxin disulfide + Acetate
S-Glutathionyl-L-cysteine + Sulfate <=> S-Sulfo-L-cysteine + Glutathione
3-Sulfinylpyruvate + H2O <=> Sulfite + Pyruvate
Homoisocitrate + NAD+ <=> Oxaloglutarate + NADH + H+
L-2-Aminoadipate adenylate + Holo-Lys2 <=> alpha-Aminoadipoyl-S-acyl enzyme + AMP
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine
S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine
Isopenicillin N + Phenylacetyl-CoA + H2O <=> Penicillin G + L-2-Aminoadipate + CoA
Biocytin + 2 Peptide <=> Holo-[carboxylase] + 2 H2O
L-2-Aminoadipate + L-Valine + L-Cysteine + 3 ATP + H2O <=> delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine + 3 AMP + 3 Diphosphate
delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine + Oxygen <=> Isopenicillin N + 2 H2O
Imidazol-5-yl-pyruvate <=> Imidazole-4-acetaldehyde + CO2
Hydantoin-5-propionate + H2O <=> N-Carbamyl-L-glutamate
Imidazol-5-yl-pyruvate + NADH + H+ <=> Imidazole lactate + NAD+
Ergothioneine <=> Thiourocanic acid + Trimethylamine
Ergothioneine <=> Hercynine
Formylisoglutamine + H2O <=> Isoglutamine
3,4-Dihydroxyphenylethyleneglycol + NAD+ <=> 3,4-Dihydroxymandelaldehyde + NADH + H+
S-Adenosyl-L-methionine + 3,4-Dihydroxyphenylethyleneglycol <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4-hydroxyphenylethyleneglycol
3,4-Dihydroxymandelaldehyde + NAD+ + H2O <=> 3,4-Dihydroxymandelate + NADH + H+
3,4-Dihydroxymandelaldehyde + NADP+ + H2O <=> 3,4-Dihydroxymandelate + NADPH + H+
2 5,6-Dihydroxyindole + Oxygen <=> 2 Indole-5,6-quinone + 2 H2O
5,6-Dihydroxyindole + CO2 <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
Indole-5,6-quinone + Oxygen <=> Eumelanin + H2O
S-Adenosyl-L-methionine + 3,4-Dihydroxymandelate <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4-hydroxymandelate
3-Methoxy-4-hydroxyphenylacetaldehyde + NAD+ + H2O <=> Homovanillate + NADH + H+
3-Methoxy-4-hydroxyphenylacetaldehyde + NADP+ + H2O <=> Homovanillate + NADPH + H+
3-Methoxytyramine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylacetaldehyde + Hydrogen peroxide + Ammonia
3-Methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADH + H+
3-Methoxy-4-hydroxyphenylglycolaldehyde + NADP+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADPH + H+
L-Normetanephrine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylglycolaldehyde + Ammonia + Hydrogen peroxide
L-Metanephrine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylglycolaldehyde + Hydrogen peroxide + Methylamine
2-Hydroxyhepta-2,4-dienedioate + H2O <=> 4-Hydroxy-2-oxo-heptanedioate
3-(2-Hydroxyphenyl)propanoate <=> Phenylpropanoate
Quercetin 3-O-glucoside + UDP-L-rhamnose <=> Rutin + UDP
Luteoforol + NADP+ <=> Eriodictyol + NADPH + H+
Eriodictyol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pentahydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O
5-Hydroxyindoleacetaldehyde + NAD+ + H2O <=> 5-Hydroxyindoleacetate + H+ + NADH
5-Hydroxyindoleacetaldehyde + Oxygen + H2O <=> 5-Hydroxyindoleacetate + Hydrogen peroxide
S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate
5-Hydroxyindoleacetate <=> 5-Hydroxyindoleacetylglycine
3-Hydroxykynurenamine + Oxygen <=> 4,8-Dihydroxyquinoline + Ammonia + Hydrogen peroxide
5-Hydroxykynurenamine + H2O + Oxygen <=> 4,6-Dihydroxyquinoline + Ammonia + Hydrogen peroxide + H2O
5-Hydroxykynurenamine + CO2 <=> 5-Hydroxykynurenine
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate + NADPH + H+ <=> 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate + NADP+
5-Hydroxy-N-formylkynurenine + H2O <=> 5-Hydroxykynurenine + Formate
5-Hydroxykynurenine + 2-Oxo acid <=> 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate + Amino acid
4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate <=> 6-Hydroxykynurenate + H2O
Quinoline-3,4-diol + Oxygen <=> Formylanthranilate + CO
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + NAD+ + H2O <=> 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate + NADH + H+
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + NADP+ + H2O <=> 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate + NADPH + H+
5-(2'-Formylethyl)-4,6-dihydroxypicolinate + CO2 <=> 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate
3-Hydroxypropionyl-CoA + NADP+ <=> 3-Oxopropionyl-CoA + NADPH + H+
CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate
CMP-2-aminoethylphosphonate + N-Acylsphingosine <=> Ceramide 2-aminoethylphosphonate + CMP
CMP-N-trimethyl-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate
Diacylglyceryl-2-aminoethylphosphonate <=> Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate
(2-Amino-1-hydroxyethyl)phosphonate <=> Lipophosphonoglycan
N-Monomethyl-2-aminoethylphosphonate <=> N-Dimethyl-2-aminoethylphosphonate
2 Ferricytochrome c + Selenite + AMP <=> 2 Ferrocytochrome c + Adenylylselenate
ATP + Adenylylselenate <=> ADP + 3'-Phosphoadenylylselenate
ATP + Selenate <=> Diphosphate + Adenylylselenate
L-Selenocystathionine + H2O <=> L-Selenocysteine + Ammonia + 2-Oxobutanoate
L-Selenocysteine + S-Adenosyl-L-methionine <=> Se-Methyl-L-selenocysteine + S-Adenosyl-L-homocysteine
2 L-Selenocysteine <=> Selenocystine
L-Selenocysteine <=> Selenocysteine seleninic acid
L-Selenocysteine <=> Se-Propenylselenocysteine Se-oxide
(5-L-Glutamyl)-peptide + Se-Methyl-L-selenocysteine <=> Peptide + gamma-Glutamyl-Se-methylselenocysteine
Se-Adenosyl-L-selenohomocysteine + H2O <=> Adenosine + Selenohomocysteine
Pentosan + H2O <=> Pentosan + D-Xylose
Pentosan + H2O <=> Pentosan + L-Arabinose
R + Se-Adenosylselenomethionine <=> CH3-R + Se-Adenosyl-L-selenohomocysteine
3'-Phosphoadenylylselenate + NADPH <=> Adenosine 3',5'-bisphosphate + Selenite + NADP+ + H+
L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate
L-Serine + Selenohomocysteine <=> L-Selenocystathionine + H2O
2 Selenohomocysteine <=> Selenohomocystine
O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate
O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate
N-Hydroxy-amino acid + Acceptor <=> 2-Oxoacid oxime + Reduced acceptor
UDP-glucose + Cyanohydrin <=> Cyanoglycoside + UDP
Cyanoglycoside + H2O <=> Cyanohydrin + D-Glucose
Acetyl-CoA + S-Substituted L-cysteine <=> CoA + S-Substituted N-acetyl-L-cysteine
R-S-Cysteinylglycine + H2O <=> S-Substituted L-cysteine + Glycine
Butyryl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexanoyl-[acp] + CO2 + Acyl-carrier protein
(R)-3-Hydroxyhexanoyl-[acp] + NADP+ <=> 3-Oxohexanoyl-[acp] + NADPH + H+
(R)-3-Hydroxyhexanoyl-[acp] <=> trans-Hex-2-enoyl-[acp] + H2O
Hexanoyl-[acp] + NAD+ <=> trans-Hex-2-enoyl-[acp] + NADH + H+
Hexanoyl-[acp] + NADP+ <=> trans-Hex-2-enoyl-[acp] + NADPH + H+
Hexanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxooctanoyl-[acp] + CO2 + Acyl-carrier protein
Octanoyl-[acp] + NAD+ <=> trans-Oct-2-enoyl-[acp] + NADH + H+
Octanoyl-[acp] + NADP+ <=> trans-Oct-2-enoyl-[acp] + NADPH + H+
Octanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxodecanoyl-[acp] + CO2 + Acyl-carrier protein
Decanoyl-[acp] + NAD+ <=> trans-Dec-2-enoyl-[acp] + NADH + H+
Decanoyl-[acp] + NADP+ <=> trans-Dec-2-enoyl-[acp] + NADPH + H+
Decanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxododecanoyl-[acp] + CO2 + Acyl-carrier protein
(R)-3-Hydroxydodecanoyl-[acp] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
(R)-3-Hydroxydodecanoyl-[acp] <=> trans-Dodec-2-enoyl-[acp] + H2O
Tetradecanoyl-[acp] + NAD+ <=> trans-Tetradec-2-enoyl-[acp] + NADH + H+
Tetradecanoyl-[acp] + NADP+ <=> trans-Tetradec-2-enoyl-[acp] + NADPH + H+
Tetradecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexadecanoyl-[acp] + CO2 + Acyl-carrier protein
Hexadecanoyl-[acp] + NAD+ <=> trans-Hexadec-2-enoyl-[acp] + NADH + H+
Hexadecanoyl-[acp] + NADP+ <=> trans-Hexadec-2-enoyl-[acp] + NADPH + H+
Uroporphyrinogen I + Reduced acceptor <=> Uroporphyrin I + Acceptor + 6 H+
Uroporphyrinogen I <=> Coproporphyrinogen I + 4 CO2
Coproporphyrinogen I + Acceptor <=> Coproporphyrin I + Reduced acceptor + 6 H+
Cobyrinate + 1-Aminopropan-2-ol + 6 Ammonia <=> Cobinamide + 7 H2O
Myoglobin <=> Globin + Heme
(3Z)-Phycocyanobilin <=> (3Z)-Phycoerythrobilin
Bilirubin beta-diglucuronide + 2 H2O + 3 Reduced acceptor <=> D-Urobilinogen + 2 D-Glucuronate + 3 Acceptor
2-Hexaprenylphenol + Oxygen + NADPH <=> 2-Hexaprenyl-6-hydroxyphenol + NADP+ + H2O
2-Hexaprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Hexaprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine
2-Polyprenylphenol + CO2 <=> 4-Hydroxy-3-polyprenylbenzoate
3-Octaprenyl-4-hydroxybenzoate <=> 2-Octaprenylphenol + CO2
2-Octaprenylphenol + Oxygen + NADPH + H+ <=> 2-Octaprenyl-6-hydroxyphenol + NADP+ + H2O
2-Octaprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Octaprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine
Demethylphylloquinol + S-Adenosyl-L-methionine <=> Phylloquinol + S-Adenosyl-L-homocysteine
Methylimidazole acetaldehyde + NAD+ + H2O <=> Methylimidazoleacetic acid + NADH + H+
cis-beta-D-Glucosyl-2-hydroxycinnamate + H2O <=> cis-2-Hydroxycinnamate + D-Glucose
cis-2-Hydroxycinnamate <=> Coumarin + H2O
all-trans-Polyprenyl diphosphate + 4-Hydroxybenzoate <=> 4-Hydroxy-3-polyprenylbenzoate + Diphosphate
2-Hydroxyphenylacetate <=> 2,6-Dihydroxyphenylacetate
GDP-mannose + beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol <=> GDP + alpha-D-Mannosyl-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol
(alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol + Dolichyl phosphate D-mannose <=> (alpha-D-Mannosyl)9-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol + Dolichyl phosphate
ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + Ammonia <=> ADP + Orthophosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine
Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP
S-Adenosyl-L-methionine + Kaempferol <=> S-Adenosyl-L-homocysteine + 3-Methoxyapigenin
Cyanidin + Succinate + CO2 + 2 H2O <=> Leucocyanidin + 2-Oxoglutarate + Oxygen + H+
Delphinidin + Succinate + CO2 + 2 H2O <=> Leucodelphinidin + 2-Oxoglutarate + Oxygen + H+
Leucodelphinidin + NADP+ <=> Dihydromyricetin + NADPH + H+
Pentahydroxyflavanone + 2-Oxoglutarate + Oxygen <=> Dihydromyricetin + Succinate + CO2
(3Z)-Phycocyanobilin + Acceptor <=> (3Z)-Phytochromobilin + Reduced acceptor + 2 H+
Bathorhodopsin <=> Lumirhodopsin
all-trans-Dehydroretinal <=> 11-cis-Dehydroretinal
all-trans-Dehydroretinal <=> Porphyropsin
11-cis-Dehydroretinal <=> Porphyropsin
Formamidopyrimidine nucleoside triphosphate + H2O <=> 2,5-Diaminopyrimidine nucleoside triphosphate + Formate
2,5-Diaminopyrimidine nucleoside triphosphate <=> 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine
N-Succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O <=> N-Succinyl-L-glutamate + NADH + H+
N4-Acetylaminobutanal + NAD+ + H2O <=> 4-Acetamidobutanoate + NADH + H+
L-erythro-4-Hydroxyglutamate + NADH + H+ <=> L-4-Hydroxyglutamate semialdehyde + NAD+ + H2O
L-erythro-4-Hydroxyglutamate + 2-Oxoglutarate <=> (4R)-4-Hydroxy-2-oxoglutarate + L-Glutamate
D-Aspartate + (4R)-4-Hydroxy-2-oxoglutarate <=> Oxaloacetate + L-erythro-4-Hydroxyglutamate
Leukotriene D4 + H2O <=> Leukotriene E4 + Glycine
Prostaglandin A2 <=> Prostaglandin C2
Prostaglandin B2 <=> Prostaglandin C2
Prostaglandin J2 <=> Delta-12-Prostaglandin J2
6-Keto-prostaglandin F1alpha + Acceptor <=> 6-Keto-prostaglandin E1 + Reduced acceptor
Thromboxane B2 + Acceptor <=> 11-Dehydro-thromboxane B2 + Reduced acceptor
trans-Cinnamoyl beta-D-glucoside + Propane-1-ol <=> Propyl cinnamate + D-Glucose
2-Propyn-1-ol + 2 Ferricytochrome c <=> 2-Propynal + 2 Ferrocytochrome c + 2 H+
2-Propylmalate + CoA <=> 2-Oxopentanoic acid + Acetyl-CoA + H2O
(S)-3-Hydroxyisobutyryl-CoA + H2O <=> CoA + (S)-3-Hydroxyisobutyrate
(S)-3-Hydroxyisobutyrate + NAD+ <=> (S)-Methylmalonate semialdehyde + NADH + H+
(R)-2,3-Dihydroxy-3-methylpentanoate + NADP+ <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate + NADPH + H+
(S)-2-Aceto-2-hydroxybutanoate <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate
(R)-2,3-Dihydroxy-3-methylpentanoate <=> (S)-3-Methyl-2-oxopentanoic acid + H2O
(S)-2-Acetolactate <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid
Thiosulfate + Dithioerythritol + H+ <=> Sulfite + Hydrogen sulfide + 4,5-cis-Dihydroxy-1,2-dithiacyclohexane
3-Deoxy-D-manno-octulosonyl-lipid IV(A) + CMP-3-deoxy-D-manno-octulosonate <=> KDO2-lipid IVA + CMP
Tetradecanoyl-[acp] + Lauroyl-KDO2-lipid IV(A) <=> KDO2-lipid A + Acyl-carrier protein
L-erythro-3-Methylmalyl-CoA <=> 2-Methylfumaryl-CoA + H2O
Parapyruvate + Ammonia <=> 4-Hydroxy-4-methylglutamate + H2O
Parapyruvate <=> 4-Methylene-2-oxoglutarate + H2O
4-Methylene-2-oxoglutarate + Ammonia <=> 4-Methyl-L-glutamate + H2O
Trigalactosyl-diacylglycerol + UDP <=> Digalactosyl-diacylglycerol + UDP-alpha-D-galactose
Phosphatidylglycerol + Diglucosyldiacylglycerol <=> 1,2-Diacyl-sn-glycerol + Glycerophosphoglycoglycerolipid
4-Hydroxyphenylethanol + UDP-glucose <=> Salidroside + UDP
Isopyridoxal + NAD+ <=> 5-Pyridoxolactone + NADH + H+
O-Phospho-4-hydroxy-L-threonine + 2-Oxoglutarate <=> 2-Oxo-3-hydroxy-4-phosphobutanoate + L-Glutamate
O-Phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate
4-Hydroxy-L-threonine <=> 3-Aminopropane-1,2-diol + CO2
Dimethylallyltryptophan <=> Elymoclavine
Iridodial <=> Iridotrial
Iridotrial <=> 7-Deoxyloganetin
ent-Copalyl diphosphate <=> ent-Kaurene + Diphosphate
Gibberellin A53 + 2-Oxoglutarate + Oxygen <=> Gibberellin A44 diacid + Succinate + CO2
6-Hydroxyhexan-6-olide <=> Adipate semialdehyde
Adipate semialdehyde + NADP+ + H2O <=> Adipate + NADPH + H+
Adipate semialdehyde <=> Cyclohexane-1,2-dione + H2O
Cytochrome P-450 oxidized form + NADPH <=> Cytochrome P-450 reduced form + NADP+ + H+
3'-Phosphoadenylyl sulfate + Digalactosylceramide <=> Adenosine 3',5'-bisphosphate + Digalactosylceramide sulfate
Ceramidepentasaccharide + GDP-L-fucose <=> Type A glycolipid + GDP
Gal-alpha1->3(Fuc-alpha1->2)Gal-beta1->3GlcNAc-beta1->3LacCer + UDP <=> Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + UDP-alpha-D-galactose
Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + UDP-N-acetyl-D-galactosamine <=> Type A glycolipid + UDP
UDP-N-acetyl-D-galactosamine + GD3 <=> UDP + GD2
UDP-alpha-D-galactose + GD2 <=> UDP + GD1b
UDP-alpha-D-galactose + GA2 <=> UDP + GA1
GA1 + H2O <=> GA2 + D-Galactose
CMP-N-acetylneuraminate + GT1a <=> CMP + GQ1
CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1
GT1b + N-Acetylneuraminate <=> GQ1 + H2O
CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b
GT1b + H2O <=> GD1b + N-Acetylneuraminate
Poly-beta-hydroxybutyrate + H2O <=> Poly[(R)-3-hydroxybutanoate]x + (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate
3-Butyn-1-al + NAD+ + H2O <=> 3-Butynoate + NADH + H+
3-Butyn-1-al + PQQ + H2O <=> 3-Butynoate + PQQH2
3-Butyn-1-al + PQQH2 <=> 3-Butyn-1-ol + PQQ
2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine + 2 S-Adenosyl-L-methionine <=> 6-(3'-Triphosphoryl-1'-methylglyceryl)-7-methyl-7,8-dihydrobiopterin + 2 S-Adenosyl-L-homocysteine + H2O
S-Adenosyl-L-methionine + (S)-Norcoclaurine <=> S-Adenosyl-L-homocysteine + (S)-Coclaurine
Codeine + NADP+ <=> Codeinone + NADPH + H+
Codeinone <=> Neopinone
Thebaine + 2-Oxoglutarate + Oxygen <=> Neopinone + Formaldehyde + Succinate + CO2
Thebaine + 2-Oxoglutarate + Oxygen <=> Oripavine + Formaldehyde + Succinate + CO2
Anabasine + CO2 <=> Piperideine + Nicotinate
Piperideine + Acetoacetyl-CoA + H2O <=> Pelletierine + CoA + CO2
Piperideine + Pelletierine <=> L-(+)-Anaferine
Pelletierine <=> N-Methylpelletierine
Protein N(pi)-phospho-L-histidine + Arbutin <=> Protein histidine + Arbutin 6-phosphate
Arbutin 6-phosphate + H2O <=> Hydroquinone + beta-D-Glucose 6-phosphate
Salicin 6-phosphate + H2O <=> Salicyl alcohol + beta-D-Glucose 6-phosphate
2',3'-Cyclic GMP + H2O <=> Guanosine 3'-phosphate
Salicylaldehyde + Pyruvate <=> trans-o-Hydroxybenzylidenepyruvate + H2O
trans-o-Hydroxybenzylidenepyruvate <=> 2-Hydroxychromene-2-carboxylate
2-Hydroxy-2,4-pentadienoate + Acetate <=> 2-Hydroxy-6-keto-2,4-heptadienoate + H2O
D-Glucose + Levan <=> Sucrose + Levan
Celloheptaose + H2O <=> Cellohexaose + D-Glucose
Cellohexaose + H2O <=> Cellopentaose + D-Glucose
Gla protein + Vitamin K1 epoxide + H2O <=> Gla protein precursor + Phylloquinol + CO2 + Oxygen
Biotinyl-5'-AMP + Apo-[carboxylase] <=> AMP + Holo-[carboxylase]
Dodecanoyl-[acyl-carrier protein] + KDO2-lipid IVA <=> Lauroyl-KDO2-lipid IV(A) + Acyl-carrier protein
Terephthalate + Oxygen + NADH + H+ <=> (3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+
2 S-Adenosyl-L-methionine + Precorrin 6Y <=> 2 S-Adenosyl-L-homocysteine + Precorrin 8X + CO2
Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+
Isoquinoline + Acceptor + H2O <=> Isocarbostyril + Reduced acceptor
Quinoline + Acceptor + H2O <=> 2(1H)-Quinolinone + Reduced acceptor
6-Chlorobenzene-1,2,4-triol + Oxygen <=> 2-Chloromaleylacetate
4-Hydroxyquinoline + Oxygen + NADH + H+ <=> Quinoline-3,4-diol + NAD+ + H2O
2-Methylquinoline-3,4-diol + Oxygen <=> N-Acetylanthranilate + CO
2-Aminobenzenesulfonate + Oxygen + NADH + H+ <=> 3-Sulfocatechol + Ammonia + NAD+
Quinolin-2-ol + Oxygen + NADH + H+ <=> 2,5,6-Trihydroxy-5,6-dihydroquinoline + NAD+
Quinolin-2-ol + Oxygen + NADH + H+ <=> Quinolin-2,8-diol + NAD+ + H2O
S-Adenosyl-L-methionine + (R,S)-Norcoclaurine <=> S-Adenosyl-L-homocysteine + (R,S)-Coclaurine
p-Coumaroyl-CoA + Anthocyanidin-3,5-diglucoside <=> CoA + Anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside
UDP-glucose + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol <=> UDP + alpha-Kojibiosyldiacylglycerol
1-Carboxyvinyl carboxyphosphonate <=> 3-(Hydrohydroxyphosphoryl)pyruvate + CO2
Lacto-N-tetraose + H2O <=> Lacto-N-biose + Lactose
Phthalylamide + H2O <=> Phthalate + Amine
N-Acetyl-D-galactosamine 6-phosphate + H2O <=> D-Galactosamine 6-phosphate + Acetate
Methylenediurea + 2 H2O <=> N-(Hydroxymethyl)urea + CO2 + 2 Ammonia
Methylenediurea + H2O <=> N-(Carboxyaminomethyl)urea + Ammonia
N-(Carboxyaminomethyl)urea <=> N-(Aminomethyl)urea + CO2
N-(Aminomethyl)urea + H2O <=> N-(Hydroxymethyl)urea + Ammonia
2-Aryl-2-methylmalonate <=> 2-Arylpropionate + CO2
16-alpha-Hydroxypregnenolone <=> 16,17-Didehydropregnenolone + H2O
omega-Agatoxin IVC <=> omega-Agatoxin IVB
ADP-D-glycero-beta-D-manno-heptose <=> ADP-L-glycero-beta-D-manno-heptose
Precorrin 8X <=> Hydrogenobyrinate
3 S-Adenosyl-L-methionine + [Ribulose-1,5-bisphosphate carboxylase]-L-lysine + H+ <=> 3 S-Adenosyl-L-homocysteine + [Ribulose-1,5-bisphosphate carboxylase]-N6,N6,N6-trimethyl-L-lysine
S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4
S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5
2 S-Adenosyl-L-methionine + 2 [Methionine synthase]-cob(II)alamin + NADPH + H+ <=> 2 [Methionine synthase]-methylcob(I)alamin + 2 S-Adenosyl-L-homocysteine + NADP+
4-Quinolinecarboxylic acid + Acceptor + H2O <=> 2-Oxo-1,2-dihydroquinoline-4-carboxylate + Reduced acceptor
16 ATP + Nitrogen + 8 Reduced ferredoxin + 8 H+ + 16 H2O <=> 16 Orthophosphate + 16 ADP + 8 Oxidized ferredoxin + 2 Ammonia + Hydrogen
16 ATP + Nitrogen + 4 Reduced flavodoxin + 16 H2O <=> 16 Orthophosphate + 16 ADP + 4 Oxidized flavodoxin + 2 Ammonia + Hydrogen
Acetyl-CoA + n Malonyl-CoA + 2n NADPH + 2n H+ <=> Long-chain fatty acid + n CO2 + 2n NADP+ + (n+1) CoA + n H2O
Acyl-CoA + n Methylmalonyl-CoA + 2n NADPH + 2n H+ + Acyl-carrier protein <=> Multi-methyl-branched acyl-[acp] + (n+1) CoA + n CO2 + 2n NADP+ + n H2O
Acetyl-CoA + n Malonyl-CoA + 2n NADPH + 4n H+ <=> Long-chain acyl-CoA + n CoA + n CO2 + 2n NADP+ + n H2O
n UDP-D-galacturonate <=> n UDP + Pectin
n ATP + Calmodulin + n Ubiquitin <=> n AMP + n Diphosphate + (Ubiquitin)n-calmodulin
Amylose + n D-Glucose <=> n Maltose
n-1 ATP + (6R)-10-Formyltetrahydropteroyldiglutamate + n-1 L-Glutamate <=> n-1 ADP + n-1 Orthophosphate + 10-Formyltetrahydrofolylpolyglutamate
Ethanol + 2 Ferricytochrome c <=> 2 Ferrocytochrome c + Acetaldehyde + 2 H+
Protein N(pi)-phospho-L-histidine + N-Acetyl-D-glucosamine <=> Protein histidine + N-Acetyl-D-glucosamine 6-phosphate
Phytic acid + ADP <=> 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate + ATP
Leukotriene E4 + L-Glutamate <=> Leukotriene F4 + H2O
Diacylglycerol + H2O <=> 1-Acylglycerol + Carboxylate
(S)-Coclaurine + (R)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Norberbamunine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
S-Adenosyl-L-methionine + (S)-Norreticuline <=> S-Adenosyl-L-homocysteine + (S)-Reticuline
S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-Norreticuline
S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-Nororientaline
S-Adenosyl-L-methionine + (S)-Norlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-6-O-Methylnorlaudanosoline
2 (R)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Guattegaumerine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
S-Adenosyl-L-methionine + (R)-Norreticuline <=> S-Adenosyl-L-homocysteine + (R)-Reticuline
Precorrin 3A + Oxygen + NADH + H+ <=> Precorrin 3B + NAD+ + H2O
2 Cob(II)yrinate a,c diamide + Reduced FMN <=> 2 Cob(I)yrinate a,c diamide + FMN + 2 H+
Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine <=> Precorrin 5 + S-Adenosyl-L-methionine + H2O
Cob(I)yrinate a,c diamide + ATP <=> Adenosyl cobyrinate a,c diamide + Triphosphate
Adenosyl cobinamide + ATP <=> Adenosyl cobinamide phosphate + ADP
Adenosyl cobinamide phosphate + GTP <=> Adenosine-GDP-cobinamide + Diphosphate
Cobamide coenzyme + GMP <=> Adenosine-GDP-cobinamide + alpha-Ribazole
Hydrogenobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Hydrogenobyrinate a,c diamide + 2 Orthophosphate + 2 L-Glutamate + 2 ADP
Adenosyl cobyrinate a,c diamide + 4 L-Glutamine + 4 ATP + 4 H2O <=> Adenosyl cobyrinate hexaamide + 4 L-Glutamate + 4 Orthophosphate + 4 ADP
Adenosyl cobyrinate hexaamide + (R)-1-Aminopropan-2-ol <=> Adenosyl cobinamide + H2O
Hydrogenobyrinate a,c diamide + Cobalt ion + ATP + H2O <=> Cob(II)yrinate a,c diamide + Orthophosphate + ADP + H+
Deacetylcephalosporin C + H2O + 2 Succinate + 2 CO2 <=> Penicillin N + 2 2-Oxoglutarate + 2 Oxygen
Deacetylcephalosporin C + Succinate + CO2 <=> Deacetoxycephalosporin C + 2-Oxoglutarate + Oxygen
Deacetylcephalosporin C + Carbamoyl phosphate <=> O-Carbamoyl-deacetylcephalosporin C + Orthophosphate
6-Hydroxyhexanoic acid + NADP+ <=> Adipate semialdehyde + NADPH + H+
p-Cumic alcohol + NAD+ <=> 4-Isopropylbenzaldehyde + NADH + H+
trans-3-Chloro-2-propene-1-ol + NAD+ <=> trans-3-Chloroallyl aldehyde + NADH + H+
cis-3-Chloro-2-propene-1-ol + NAD+ <=> cis-3-Chloroallyl aldehyde + NADH + H+
4-Isopropylbenzaldehyde + NAD+ + H2O <=> p-Cumate + NADH + H+
cis,cis-4-Hydroxymuconic semialdehyde + NAD+ + H2O <=> 2-Maleylacetate + NADH + H+
trans-3-Chloroallyl aldehyde + H2O <=> trans-3-Chloroacrylic acid + 2 H+
cis-3-Chloroallyl aldehyde + H2O <=> cis-3-Chloroacrylic acid + 2 H+
cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NAD+ <=> Biphenyl-2,3-diol + NADH + H+
cis-2,3-Dihydroxy-2,3-dihydro-p-cumate + NAD+ <=> 2,3-Dihydroxy-p-cumate + NADH + H+
cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NAD+ <=> 2,3-Dihydroxy-4'-chlorobiphenyl + NADH + H+
2,5-Dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ <=> 2,5-Dichlorohydroquinone + NADH + H+
p-Benzoquinone + NADPH + H+ <=> Hydroquinone + NADP+
2,3-Dihydroxy-4'-chlorobiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate
Hydroquinone + Oxygen <=> cis,cis-4-Hydroxymuconic semialdehyde
p-Cumate + Oxygen + NADH + H+ <=> cis-2,3-Dihydroxy-2,3-dihydro-p-cumate + NAD+
2,3-Dihydroxy-p-cumate + Oxygen <=> 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate
Resorcinol + Oxygen + NADPH + H+ <=> Benzene-1,2,4-triol + NADP+ + H2O
1,2,3-Trihydroxybenzene + NADP+ + H2O <=> Resorcinol + Oxygen + NADPH + H+
2,2-Bis(4'-chlorophenyl)ethanol + H2O <=> Bis(4'-chlorophenyl)acetate + 4 H+
4-Chlorobenzoate <=> 4-Chlorobenzaldehyde + H2O
1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Reduced acceptor + 2 H+ <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethane + Acceptor
1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene + Oxygen <=> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate
2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + Oxygen <=> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate
p-Benzoquinone + Nitrite + NADP+ + H2O <=> 4-Nitrophenol + Oxygen + NADPH + H+
Parathion + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Paraoxon + [Oxidized NADPH---hemoprotein reductase] + Sulfur + H2O
DDT + Reduced acceptor + Oxygen <=> cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + Acceptor
4-Chlorobiphenyl + Oxygen + NADH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NAD+
4-Chlorobiphenyl + Oxygen + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NADP+
Biphenyl + Oxygen + NADH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NAD+
Biphenyl + Oxygen + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NADP+
4-Nitrocatechol + Oxygen + 3 H+ <=> Benzene-1,2,4-triol + Nitrite + H2O
p-Cymene + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> p-Cumic alcohol + 2 Oxidized ferredoxin + H2O
Hydrochloric acid + Hydroquinone + Glutathione disulfide <=> Chlorohydroquinone + 2 Glutathione
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + H+ <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Cl-
2,5-Dichlorohydroquinone + 2 Glutathione <=> Chlorohydroquinone + Glutathione disulfide + Hydrochloric acid
6-Deoxyerythronolide B + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Erythronolide B + 2 Oxidized ferredoxin + H2O
4-Sulfobenzyl alcohol + NAD+ <=> 4-Sulfobenzaldehyde + NADH + H+
4-Sulfobenzaldehyde + NAD+ + H2O <=> 4-Sulfobenzoate + NADH + H+
Vanillate + NAD+ + H2O <=> 4-Hydroxy-3-methoxy-benzaldehyde + Oxygen + NADH + H+
Vanillate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde
cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ <=> 4,5-Dihydroxyphthalate + NADH + H+
4-Chlorobenzoyl-CoA + Hydrochloric acid + NADP+ <=> 2,4-Dichlorobenzoyl-CoA + NADPH + H+
4-Aminobenzenesulfonate + 4-Aminobenzoate <=> 4-Carboxy-4'-sulfoazobenzene + 4 H+
4-Sulfocatechol + Oxygen <=> 3-Sulfomuconate
4-Aminobenzenesulfonate + Oxygen + 2 H+ <=> 4-Sulfocatechol + Ammonia
3,4-Dihydroxybenzoate + Ammonia <=> 4-Aminobenzoate + Oxygen + 2 H+
Toluene-4-sulfonate + Oxygen + NADH + H+ <=> 4-Sulfobenzyl alcohol + NAD+ + H2O
4-Methylbenzyl alcohol + NAD+ <=> p-Tolualdehyde + NADH + H+
6-Hydroxyhexanoic acid + NAD+ <=> Adipate semialdehyde + NADH + H+
1,2-Dichloroethane + H2O <=> 2-Chloroethanol + Hydrochloric acid
2-Chloroethanol + 2 Ferricytochrome c <=> Chloroacetaldehyde + 2 Ferrocytochrome c + 2 H+
Chloroacetaldehyde + NAD+ + H2O <=> Chloroacetic acid + NADH + H+
Chloroacetic acid + H2O <=> Glycolate + Hydrochloric acid
p-Xylene + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> 4-Methylbenzyl alcohol + 2 Oxidized ferredoxin + H2O
p-Tolualdehyde + NADP+ + H2O <=> Toluate + NADPH + H+
Toluate + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD+
Toluate + Oxygen + NADPH + H+ <=> cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+
cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD+ <=> 4-Methylcatechol + CO2 + NADH + H+
cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ <=> 4-Methylcatechol + CO2 + NADPH + H+
Toluene-4-sulfonate + Oxygen + NADH + H+ <=> 4-Methylcatechol + Sulfite + NAD+
4-Methylcatechol + Oxygen <=> 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + H2O <=> Formate + (4E)-2-Oxohexenoic acid
(4E)-2-Oxohexenoic acid + H2O <=> 4-Hydroxy-2-oxohexanoic acid
Propanal + Pyruvate <=> 4-Hydroxy-2-oxohexanoic acid
4-Methylcatechol + Oxygen <=> 3-Methyl-cis,cis-hexadienedioate
4-Methylmuconolactone <=> 3-Methyl-cis,cis-hexadienedioate
Penicillin N + 2-Oxoglutarate + Oxygen <=> Deacetoxycephalosporin C + Succinate + CO2 + H2O
O-Carbamoyl-deacetylcephalosporin C + 2-Oxoglutarate + Oxygen <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + Succinate + CO2
Cephamycin C + S-Adenosyl-L-homocysteine <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + S-Adenosyl-L-methionine
Nucleoside + Deoxynucleoside 5'-phosphate <=> Deoxynucleoside + Nucleoside 3'-phosphate
3-Hydroxypimeloyl-CoA + NAD+ <=> 3-Oxopimeloyl-CoA + NADH + H+
Formaldehyde + Mycothiol + NAD+ <=> S-Formylmycothiol + NADH + H+
Dihydrophloroglucinol + NADP+ <=> Phloroglucinol + NADPH + H+
1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ <=> 2,3-Dihydroxytoluene + CO2 + NADH + H+
cis-1,2-Dihydroxy-1,2-dihydrodibenzothiophene + NAD+ <=> 1,2-Dihydroxydibenzothiophene + NADH + H+
6-Carboxyhexanoyl-CoA + NAD+ <=> 6-Carboxyhex-2-enoyl-CoA + NADH + H+
5,6-Dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+ <=> 5,6-Dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H+
cis-1,2-Dihydro-3-ethylcatechol + NAD+ <=> 3-Ethylcatechol + NADH + H+
1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ <=> 2,3-Dihydroxytoluene + NADH + CO2 + H+
(1S,3R,4S)-3,4-Dihydroxycyclohexane-1-carboxylate + NAD+ <=> (1S,4S)-4-Hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H+
4-Hydroxybenzoyl-CoA + Reduced ferredoxin <=> Benzoyl-CoA + Oxidized ferredoxin + H2O
L-Tryptophan + Oxygen <=> alpha,beta-Didehydrotryptophan + Hydrogen peroxide
Ferrocytochrome c + Fe3+ <=> Ferricytochrome c + Fe2+
Taurine + 2-Oxoglutarate + Oxygen <=> Sulfite + Aminoacetaldehyde + Succinate + CO2
Tetradecanoyl-CoA + NADH + Oxygen + H+ <=> (E)-11-Tetradecenoyl-CoA + NAD+ + 2 H2O
Tetradecanoyl-CoA + NADH + Oxygen + H+ <=> (Z)-11-Tetradecenoyl-CoA + NAD+ + 2 H2O
S-Adenosyl-L-methionine + 3-O-Methylquercetin <=> S-Adenosyl-L-homocysteine + 3,7-Di-O-methylquercetin
UDP-glucose + cis-p-Coumarate <=> 4'-O-beta-D-Glucosyl-cis-p-coumarate + UDP
UDP-glucose + Limonin <=> Glucosyl-limonin + UDP
Lacto-N-biose + Orthophosphate <=> alpha-D-Galactose 1-phosphate + N-Acetyl-D-glucosamine
n UDP-N-acetyl-alpha-D-glucosamine + n UDP-glucuronate <=> Hyaluronate + 2n UDP
ADP-glucose + sn-Glycerol 3-phosphate <=> 2-(alpha-D-Glucosyl)-sn-glycerol 3-phosphate + ADP
[eIF5A-precursor]-lysine + Spermidine <=> [eIF5A-precursor]-deoxyhypusine + 1,3-Diaminopropane
4,8,12-Trimethyltridecanoyl-CoA + Propanoyl-CoA <=> 3-Oxopristanoyl-CoA + CoA
3-Methylbutanoyl-CoA + 3 Malonyl-CoA <=> 4 CoA + 3 CO2 + Phlorisovalerophenone
Acetyl-CoA + alpha-D-Glucosamine 1-phosphate <=> CoA + N-Acetyl-alpha-D-glucosamine 1-phosphate
Phospholipid + 1,2-Diacyl-sn-glycerol <=> Lysophospholipid + Triacylglycerol
N-Methylputrescine + Oxygen + H2O <=> 4-Methylaminobutanal + Hydrogen peroxide + Ammonia
4-Methylaminobutanal <=> 1-Methylpyrrolinium + H2O
4-Hydroxybutanoic acid + Acetyl-CoA <=> 4-Hydroxybutyryl-CoA + Acetate
4-Hydroxybutyryl-CoA <=> Vinylacetyl-CoA + H2O
D-Ribulose 5-phosphate + Formaldehyde <=> D-arabino-Hex-3-ulose 6-phosphate
D-arabino-Hex-3-ulose 6-phosphate <=> D-Fructose 6-phosphate
Lycopene <=> gamma-Carotene
4-Chloroacetophenone <=> 4-Chlorobenzaldehyde + CO2
beta-Carotene + 2 Reduced acceptor + 2 Oxygen <=> Echinenone + 2 Acceptor + 3 H2O
Parathion + 3 Reduced acceptor <=> Aminoparathion + 3 Acceptor + 2 H2O
3-Methylbenzyl alcohol + NAD+ <=> 3-Methylbenzaldehyde + NADH + H+
2-Methylbenzyl alcohol + NAD+ <=> 2-Methylbenzaldehyde + NADH + H+
Fluoren-9-ol + NAD+ <=> Fluoren-9-one + NADH + H+
Fluoren-9-ol + NADP+ <=> Fluoren-9-one + NADPH + H+
Ethylene oxide + CoA + NAD+ <=> Acetyl-CoA + NADH + H+
(S)-1-Phenylethanol + NAD+ <=> Acetophenone + NADH + H+
2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + NAD+ + H2O <=> 2-Hydroxy-5-methyl-cis,cis-muconate + NADH + H+
Styrene-cis-2,3-dihydrodiol + NAD+ <=> 3-Vinylcatechol + NADH + H+
2-Chloromaleylacetate + NADH <=> 2-Maleylacetate + NAD+ + Cl-
epsilon-Caprolactam + H2O <=> 6-Aminohexanoate
Guanidinoproclavaminic acid + H2O <=> Proclavaminic acid + Urea
Acrylonitrile + 2 H2O <=> Acrylic acid + Ammonia
2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate + H2O <=> 4-Chlorobenzoate + 2-Hydroxy-2,4-pentadienoate
2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate + H2O <=> Salicylate + 2-Hydroxy-2,4-pentadienoate
2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate + H2O <=> 2-Hydroxymuconate + Catechol
2-Hydroxy-6-oxoocta-2,4,7-trienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Acrylic acid
6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate + H2O <=> 2-(4'-Chlorophenyl)-3,3-dichloropropenoate + 2-Hydroxy-3-chloropenta-2,4-dienoate
2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O <=> 2-Methylpropanoate + 2-Hydroxy-2,4-pentadienoate
2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Anthranilate
2-Hydroxy-6-oxo-octa-2,4-dienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Propanoate
trans-1,3-Dichloropropene + H2O <=> trans-3-Chloro-2-propene-1-ol + Hydrochloric acid
cis-1,3-Dichloropropene + H2O <=> cis-3-Chloro-2-propene-1-ol + Hydrochloric acid
1,3,4,6-Tetrachloro-1,4-cyclohexadiene + H2O <=> 2,4,5-Trichloro-2,5-cyclohexadiene-1-ol + Hydrochloric acid
2,4,5-Trichloro-2,5-cyclohexadiene-1-ol + H2O <=> 2,5-Dichloro-2,5-cyclohexadiene-1,4-diol + Hydrochloric acid
trans-3-Chloroacrylic acid + H2O <=> Hydrochloric acid + 3-Oxopropanoate
cis-3-Chloroacrylic acid + H2O <=> Hydrochloric acid + 3-Oxopropanoate
Methylmalonyl-CoA <=> Propanoyl-CoA + CO2
2-Oxo-5-methyl-cis-muconate <=> 2-Hydroxy-cis-hex-2,4-dienoate + CO2
4-Hydroxyphthalate <=> 3-Hydroxybenzoate + CO2
Bis(4'-chlorophenyl)methane + CO2 <=> Bis(4'-chlorophenyl)acetate
2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate <=> 2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate + CO2
2-Deoxy-5-keto-D-gluconic acid 6-phosphate <=> 3-Oxopropanoate + Glycerone phosphate
Acrylamide <=> Acrylonitrile + H2O
Acetaldehyde <=> Acetylene + H2O
Ethanolamine + Acetaldehyde <=> Diethanolamine
Triethanolamine <=> Diethanolamine + Acetaldehyde
2-Aminophenol <=> Hydroxylaminobenzene
TDE <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Hydrochloric acid
1-Chloro-2,2-bis(4'-chlorophenyl)ethane <=> unsym-Bis(4'-chlorophenyl)ethylene + Hydrochloric acid
Lindane <=> gamma-Pentachlorocyclohexene + Hydrochloric acid
gamma-Pentachlorocyclohexene <=> 1,3,4,6-Tetrachloro-1,4-cyclohexadiene + Hydrochloric acid
5-Chloro-1,2,4-trihydroxybenzene <=> 2-Hydroxy-1,4-benzoquinone + Hydrochloric acid
2-Hydroxy-5-methyl-cis,cis-muconate <=> 2-Oxo-5-methyl-cis-muconate
3-Chloro-cis,cis-muconate <=> Protoanemonin + Hydrochloric acid + CO2
3-Chloro-cis,cis-muconate <=> cis-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid
trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid <=> 2,5-Dichloro-cis,cis-muconate
2,4-Dichloro-cis,cis-muconate <=> trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid
3-Sulfomuconate <=> 4-Sulfolactone
cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NAD+ <=> 2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADH + H+
cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADP+ <=> 2,3-Dihydroxy 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane + NADPH + H+
3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3,6-Dichlorocatechol + NADH + H+
1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + 2 H+ + 2 e- <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethane
2-Hydroxy-1,4-benzoquinone + NADH + H+ <=> Benzene-1,2,4-triol + NAD+
Nitrosobenzene + NADPH + H+ <=> Hydroxylaminobenzene + NADP+
Nitrobenzene + NADPH + H+ <=> Nitrosobenzene + NADP+ + H2O
Tetrachlorohydroquinone + 2 Glutathione <=> 2,3,6-Trichlorohydroquinone + Glutathione disulfide + Hydrochloric acid
2,3,6-Trichlorohydroquinone + 2 Glutathione <=> 2,6-Dichlorohydroquinone + Glutathione disulfide + Hydrochloric acid
3-Vinylcatechol + Oxygen <=> 2-Hydroxy-6-oxoocta-2,4,7-trienoate
2-Aminophenol + Oxygen <=> 2-Aminomuconate semialdehyde
4-Chlorocatechol + Oxygen <=> 5-Chloro-2-hydroxymuconic semialdehyde
3,5-Dichlorocatechol + Oxygen <=> 2,4-Dichloro-cis,cis-muconate
2,6-Dichlorohydroquinone + Oxygen + H2O <=> 2-Chloromaleylacetate + Hydrochloric acid
3,6-Dichlorocatechol + Oxygen <=> 2,5-Dichloro-cis,cis-muconate
3,4-Dihydroxyfluorene + Oxygen <=> 2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid
2,2',3-Trihydroxybiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate
1,2-Dihydroxyfluorene + Oxygen <=> 2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid
2,2',3-Trihydroxydiphenylether + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate
Carbazole + Oxygen + NADH + H+ <=> 2'-Aminobiphenyl-2,3-diol + NAD+
2'-Aminobiphenyl-2,3-diol + Oxygen <=> 2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate
3-Ethylcatechol + Oxygen <=> 2-Hydroxy-6-oxo-octa-2,4-dienoate + H+
Styrene + Oxygen + NADH + H+ <=> Styrene-cis-2,3-dihydrodiol + NAD+
2,4,5-Trichlorophenoxyacetic acid + Oxygen + NADH + H+ <=> 2,4,5-Trichlorophenol + Glyoxylate + NAD+ + H2O
2,4-Dichlorophenoxyacetate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Glyoxylate + Succinate + CO2
4-Sulfolactone + H2O <=> HSO3- + 2-Maleylacetate + H+
Parathion + H2O <=> Diethylthiophosphoric acid + 4-Nitrophenol
Fluorene + Oxygen + NADH + H+ <=> Fluoren-9-ol + NAD+ + H2O
Fluorene + Oxygen + NADH + H+ <=> (+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene + NAD+
Ethylbenzene <=> Styrene + 2 H+
Ethylbenzene + Oxygen + NADH + H+ <=> (S)-1-Phenylethanol + NAD+ + H2O
(S)-1-Phenylethanol + Oxygen + NADH + H+ <=> Acetophenone + NAD+ + 2 H2O
2 Acetophenone + Oxygen <=> 2 2-Hydroxyacetophenone
o-Toluate + Oxygen + NADH + H+ <=> 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+
1,4-Dichlorobenzene + Oxygen + NADH + H+ <=> 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
2 Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 Dihydrocoumarin + 2 NAD+
2 Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 3-Hydroxy-1-indanone + 2 NAD+
2 Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 Dihydrocoumarin + 2 NADP+
2 Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 3-Hydroxy-1-indanone + 2 NADP+
Dibenzofuran + Oxygen + NADH + H+ <=> 2,2',3-Trihydroxybiphenyl + NAD+
Fluoren-9-one + Oxygen + 2 NADH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NAD+
Fluoren-9-one + Oxygen + 2 NADPH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NADP+
2 2-Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 3-Isochromanone + 2 NAD+
2 2-Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 3-Isochromanone + 2 NADP+
Dibenzo-p-dioxin + Oxygen + NADH + H+ <=> 2,2',3-Trihydroxydiphenylether + NAD+
Ethylbenzene + Oxygen + NADH + H+ <=> cis-1,2-Dihydro-3-ethylcatechol + NAD+
4-Chlorophenol + Oxygen + NADPH + H+ <=> 4-Chlorocatechol + NADP+ + H2O
o-Xylene + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> 2-Methylbenzyl alcohol + 2 Oxidized ferredoxin + H2O
m-Xylene + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> 3-Methylbenzyl alcohol + 2 Oxidized ferredoxin + H2O
Ethylene + Oxygen + NADH + H+ <=> Ethylene oxide + NAD+ + H2O
2,6-Dichlorohydroquinone + H2O <=> 6-Chlorobenzene-1,2,4-triol + Hydrochloric acid
2,5-Dichlorohydroquinone + FADH2 + Oxygen <=> 5-Chloro-2-hydroxy-p-benzoquinone + FAD + H2O + Cl-
2,4,5-Trichlorophenol + FADH2 + Oxygen <=> 2,5-Dichloro-p-benzoquinone + FAD + H2O + Cl-
2,6-Dichlorophenol + Oxygen + NADH + H+ <=> 2,6-Dichlorohydroquinone + NAD+ + H2O
2,4,6-Trichlorophenol + FADH2 + Oxygen <=> 2,6-Dichloro-p-benzoquinone + FAD + H2O + Cl-
2-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> Homogentisate + NAD+ + H2O
CoA + ATP + 2,4-Dichlorobenzoate <=> Diphosphate + 2,4-Dichlorobenzoyl-CoA + AMP
3-Oxo-3-phenylpropanoate + CoA + ATP <=> Diphosphate + Benzoylacetyl-CoA + AMP
2 ATP + Acetophenone + HCO3- + H2O + H+ <=> 2 ADP + 2 Orthophosphate + 3-Oxo-3-phenylpropanoate
2-Succinylbenzoate <=> Spirodilactone + H2O
2-Succinylbenzoyl-CoA <=> Spirodilactone + CoA
4-Keto-anhydrotetracycline + FADH2 + Cl- + Oxygen + H+ <=> 4-Ketoanhydrochlortetracycline + FAD + 2 H2O
Tetracycline + Coenzyme F420 <=> 5a,11a-Dehydrotetracycline + Reduced coenzyme F420
4-Hydroxy-6-methylpretetramide + NADPH + Oxygen + H+ <=> 4-Keto-anhydrotetracycline + NADP+ + H2O
6-Methylpretetramide + NADPH + Oxygen + H+ <=> 4-Hydroxy-6-methylpretetramide + NADP+ + H2O
D-Glyceraldehyde 3-phosphate + L-Arginine <=> L-N2-(2-Carboxyethyl)arginine + Orthophosphate
Deoxyguanidinoproclavaminic acid + 2-Oxoglutarate + Oxygen <=> Guanidinoproclavaminic acid + Succinate + CO2
L-N2-(2-Carboxyethyl)arginine + ATP <=> Deoxyguanidinoproclavaminic acid + AMP + Diphosphate
Proclavaminic acid + Oxygen + 2-Oxoglutarate <=> Dihydroclavaminic acid + CO2 + Succinate + H2O
Dihydroclavaminic acid + Oxygen + 2-Oxoglutarate <=> Clavaminic acid + Succinate + CO2 + H2O
Clavaminic acid <=> Clavulanate-9-aldehyde
Clavulanate-9-aldehyde + NADPH + H+ <=> Clavulanic acid + NADP+
6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate <=> 4-Chlorobenzoate
Bis(4'-chlorophenyl)methane <=> 4-Chlorophenylacetate
2-(4'-Chlorophenyl)-3,3-dichloropropenoate <=> 4-Chlorophenylacetate
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + NADH + H+ + Oxygen <=> cis-3-[2,2-Dichloro-1-(4-chlorophenyl)vinyl]-6-chlorocyclohexa-3,5-diene-1,2-diol + NAD+
DDT <=> TDE + Cl-
1-Chloro-2,2-bis(4'-chlorophenyl)ethane + H2O <=> 2,2-Bis(4'-chlorophenyl)ethanol + Hydrochloric acid
2,2-Bis(4'-chlorophenyl)ethanol <=> unsym-Bis(4'-chlorophenyl)ethylene + H2O
Bis(4'-chlorophenyl)acetate <=> 4,4'-Dichlorobenzophenone
2-(4'-Chlorophenyl)-3,3-dichloropropenoate <=> 4-Chloroacetophenone
Bis(4'-chlorophenyl)acetate <=> 2,2-Bis(4'-chlorophenyl)ethanol + H2O
Hydroquinone + Nitrite + 7 H+ + 6 e- <=> 4-Hydroxyaniline + 3 H2O
1,2,4-Trichlorobenzene + Hydrochloric acid <=> 1,3,4,6-Tetrachloro-1,4-cyclohexadiene
2,4,5-Trichloro-2,5-cyclohexadiene-1-ol <=> 2,5-Dichlorophenol + Hydrochloric acid
Aminoparathion + H2O <=> Diethylthiophosphoric acid + 4-Hydroxyaniline
Diethylthiophosphoric acid + H2O <=> Diethylphosphoric acid + Hydrogen sulfide
Phenylacetic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2-Hydroxyphenylacetate + [Oxidized NADPH---hemoprotein reductase] + H2O
Styrene + FADH2 + Oxygen <=> (S)-2-Phenyloxirane + FAD + H2O
DDT + Oxygen <=> cis-2,3-Dihydrodiol 1,1,1-Trichloro-2,2-bis(4'-chlorophenyl)ethane
4-Chlorophenoxyacetate + 2-Oxoglutarate + Oxygen <=> 4-Chlorophenol + Glyoxylate + Succinate + CO2
Ethylbenzene + H2O <=> 1-Phenylethanol + 2 H+
Acetylene + Reduced ferredoxin + 2 H+ + ATP + H2O <=> Ethylene + Oxidized ferredoxin + ADP + Orthophosphate
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Cl-
Vinyl chloride + 2 H+ <=> Ethylene + Hydrochloric acid
Tetrachloroethene + 2 H+ <=> Trichloroethene + Hydrochloric acid
Trichloroethene + 2 H+ <=> trans-1,2-Dichloroethene + Hydrochloric acid
Trichloroethene + 2 H+ <=> cis-1,2-Dichloroethene + Hydrochloric acid
trans-1,2-Dichloroethene + 2 H+ <=> Vinyl chloride + Hydrochloric acid
cis-1,2-Dichloroethene + 2 H+ <=> Vinyl chloride + Hydrochloric acid
5-Chloro-2-hydroxymuconic semialdehyde + H+ <=> 2-Hydroxymuconate semialdehyde + Cl-
2,4-Dichlorophenoxyacetate + H+ + 2 e- <=> 4-Chlorophenoxyacetate + Cl-
Benzoylacetyl-CoA + CoA <=> Benzoyl-CoA + Acetyl-CoA
6-Aminohexanoate + 2-Oxoglutarate <=> Adipate semialdehyde + L-Glutamate
Lactoyl-CoA + Acetate <=> (S)-Lactate + Acetyl-CoA
Acetyl-CoA + Acrylic acid <=> Acetate + Propenoyl-CoA
Protoanemonin + H2O <=> cis-Acetylacrylate
cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + H2O <=> 2-Chloromaleylacetate
D-Glucose 1-phosphate + Nucleoside triphosphate + Amino group donor + Activated methyl group <=> NDP-N-methyl-L-glucosamine + Orthophosphate
Streptomycin 6-phosphate + NADH + H+ <=> Dihydrostreptomycin 6-phosphate + NAD+
dTDP-L-rhamnose <=> dTDP-L-dihydrostreptose
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + H2O
Erythromycin + Oxygen <=> Erythromycin E + H2O
S-Adenosyl-L-methionine + Erythromycin C <=> S-Adenosyl-L-homocysteine + Erythromycin
Erythromycin B + NADPH + H+ + Oxygen <=> Erythromycin + NADP+ + H2O
Erythromycin D + NADPH + H+ + Oxygen <=> Erythromycin C + NADP+ + H2O
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + NADPH + H+ <=> dTDP-4-oxo-2,6-dideoxy-D-glucose + NADP+
Erythronolide B + dTDP-L-mycarose <=> 3-O-alpha-Mycarosylerythronolide B + dTDP
dTDP-D-desosamine + 3-O-alpha-Mycarosylerythronolide B <=> Erythromycin D + dTDP
S-Adenosyl-L-methionine + Erythromycin D <=> S-Adenosyl-L-homocysteine + Erythromycin B
beta-1,2,3,4,5,6-Hexachlorocyclohexane <=> delta-3,4,5,6-Tetrachlorocyclohexene + 2 Cl-
delta-3,4,5,6-Tetrachlorocyclohexene <=> 5,6-Dichloro-1,3-cyclohexadiene + 2 Cl-
5,6-Dichloro-1,3-cyclohexadiene <=> Chlorobenzene + Cl- + H+
5,6-Dichloro-1,3-cyclohexadiene <=> Benzene + 2 Cl-
3-(2-Hydroxyphenyl)propanoate + ATP + CoA + FAD + NAD+ <=> Salicylate + AMP + Diphosphate + FADH2 + Acetyl-CoA + NADH + H+
2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid + H2O <=> 2-Formyl-1-indanone + Pyruvate
CO2 <=> 3-Isochromanone
2 Indanone + 2 CO2 <=> 2 2-Formyl-1-indanone + Oxygen
Fluorene + Oxygen + 2 H+ <=> 3,4-Dihydroxyfluorene
Fluorene + Oxygen + 2 H+ <=> 1,2-Dihydroxyfluorene
3,4-Dihydroxy-3,4-dihydro-9-fluorenone <=> 4-Hydroxy-9-fluorenone + H2O
2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid + H2O <=> 1-Formyl-2-indanone + Pyruvate
1-Formyl-2-indanone + H2O <=> 2-Indanone + CO2 + 2 H+ + 2 e-
2-Amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 H2O <=> 1,4-Cyclohexanedione + Ammonia + CO2 + CoA
N1-Amidinostreptamine 6-phosphate + L-Arginine <=> Streptidine 6-phosphate + L-Ornithine
Paraoxon + H2O <=> Diethylphosphoric acid + 4-Nitrophenol
D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose
Acrylic acid + Ammonia <=> Acrylamide + H2O
Chorismate + Ammonia <=> 4-Amino-4-deoxychorismate + H2O
4-Amino-4-deoxychorismate <=> 4-Aminobenzoate + Pyruvate
(S)-Ureidoglycine + H2O <=> (S)-Ureidoglycolate + Ammonia
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate <=> trans,trans,cis-Geranylgeranyl diphosphate + Diphosphate
trans,trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> Dehydrodolichol diphosphate + n Diphosphate
Atrazine + H2O <=> Hydroxyatrazine + Hydrochloric acid
Hydroxyatrazine + H2O <=> N-Isopropylammelide + Ethylamine
N-Isopropylammelide + H2O <=> Cyanuric acid + Isopropylamine
Biuret + H2O <=> Urea-1-carboxylate + Ammonia
2 Atrazine + Oxygen <=> 2 Deisopropylatrazine + 2 Acetone
2 Atrazine + Oxygen <=> 2 Deethylatrazine + 2 Acetaldehyde
UDP-N-acetyl-D-mannosamine + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + N-Acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
2 Deisopropylatrazine + Oxygen <=> 2 Deisopropyldeethylatrazine + 2 Acetaldehyde
2 Deethylatrazine + Oxygen <=> 2 Deisopropyldeethylatrazine + 2 Acetone
Deisopropyldeethylatrazine + H2O <=> 2-Chloro-4-hydroxy-6-amino-1,3,5-triazine + Ammonia
Galactitol + Protein N(pi)-phospho-L-histidine <=> Galactitol 1-phosphate + Protein histidine
Galactitol 1-phosphate + NAD+ <=> D-Tagatose 6-phosphate + NADH + H+
Deisopropylatrazine + H2O <=> Deisopropylhydroxyatrazine + Hydrochloric acid
N-Ethylammelide + H2O <=> Cyanuric acid + Ethylamine
Deisopropylhydroxyatrazine + H2O <=> N-Ethylammelide + Ammonia
(Hydroxymethylphenyl)succinyl-CoA + NAD+ <=> Benzoylsuccinyl-CoA + NADH + H+
3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
tRNA(Asp) + L-Aspartate + ATP <=> L-Aspartyl-tRNA(Asp) + Diphosphate + AMP
tRNA(Glu) + L-Glutamate + ATP <=> L-Glutamyl-tRNA(Glu) + Diphosphate + AMP
Glutaryl-CoA + Acceptor <=> Glutaconyl-1-CoA + Reduced acceptor
CMP-N-acetylneuraminate + beta-D-Galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ <=> 6-Oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+
2-Hydroxycyclohexane-1-carboxyl-CoA + NAD+ <=> 2-Ketocyclohexane-1-carboxyl-CoA + NADH + H+
2,6-Dihydroxycyclohexane-1-carboxyl-CoA + Acceptor <=> 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA + Reduced acceptor
Benzylsuccinyl-CoA + 2 Electron-transferring flavoprotein <=> E-Phenylitaconyl-CoA + 2 Reduced electron-transferring flavoprotein
Anthraniloyl-CoA + 2 H+ <=> Benzoyl-CoA + Ammonia
3-Oxopimeloyl-CoA + CoA <=> Glutaryl-CoA + Acetyl-CoA
Benzoylsuccinyl-CoA + CoA <=> Benzoyl-CoA + Succinyl-CoA
Benzylsuccinate + Succinyl-CoA <=> Benzylsuccinyl-CoA + Succinate
Benzamide + H2O <=> Benzoate + Ammonia
Benzonitrile + 2 H2O <=> Benzoate + Ammonia
2-Ketocyclohexane-1-carboxyl-CoA + H2O <=> 6-Carboxyhexanoyl-CoA
2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA
6-Oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O <=> 3-Hydroxypimeloyl-CoA
Crotonoyl-CoA + H2O <=> 3-Hydroxybutanoyl-CoA
Benzonitrile + H2O <=> Benzamide
Cyclohexa-1,5-diene-1-carbonyl-CoA + H2O <=> 6-Hydroxycyclohex-1-ene-1-carbonyl-CoA
Toluene + Fumarate <=> Benzylsuccinate
E-Phenylitaconyl-CoA + H2O <=> (Hydroxymethylphenyl)succinyl-CoA
Cyclohex-1-ene-1-carboxyl-CoA + H2O <=> 2-Hydroxycyclohexane-1-carboxyl-CoA
6-Carboxyhex-2-enoyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2,6-Dihydroxycyclohexane-1-carboxyl-CoA
Phenolic phosphate + CO2 + H2O <=> 4-Hydroxybenzoate + Orthophosphate
D-Arabitol + NAD+ <=> D-Xylulose + NADH + H+
2-Dehydro-3-deoxy-6-phospho-D-gluconate <=> D-Glyceraldehyde 3-phosphate + Pyruvate
D-Mannonate <=> 2-Dehydro-3-deoxy-D-gluconate + H2O
Sorbitol 6-phosphate + NAD+ <=> beta-D-Fructose 6-phosphate + NADH + H+
D-Galactarate <=> 5-Dehydro-4-deoxy-D-glucarate + H2O
Cyclohexa-1,5-diene-1-carbonyl-CoA <=> Cyclohex-2,5-diene-1-carboxyl-CoA
Cyclohexa-1,5-diene-1-carbonyl-CoA <=> Cyclohex-1,4-diene-1-carboxyl-CoA
all-trans-Octaprenyl diphosphate + Diphosphate <=> all-trans-Heptaprenyl diphosphate + Isopentenyl diphosphate
all-trans-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + Diphosphate
all-trans-Pentaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + Diphosphate
all-trans-Octaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Octaprenyl-4-hydroxybenzoate + Diphosphate
all-trans-Hexaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Hexaprenyl-4-hydroxybenzoate + Diphosphate
Chlorophyll a + H2O <=> Chlorophyllide + Phytol
Cyclohexane-1-carboxyl-CoA + Acceptor <=> Cyclohex-1-ene-1-carboxyl-CoA + Reduced acceptor
Cyclohexane-1-carboxylate + CoA + ATP <=> Cyclohexane-1-carboxyl-CoA + AMP + Diphosphate
Benzoate + NADH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
Benzoate + NADPH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NADP+
Trimethylamine + NADPH + H+ + Oxygen <=> Trimethylamine N-oxide + NADP+ + H2O
H2O + Levan(m+n) <=> Levan(m) + Levan(n)
Phenol + ATP + H2O <=> Phenolic phosphate + AMP + Orthophosphate
ATP + di-trans,poly-cis-Undecaprenol <=> ADP + di-trans,poly-cis-Undecaprenyl phosphate
di-trans,poly-cis-Undecaprenyl diphosphate + H2O <=> di-trans,poly-cis-Undecaprenyl phosphate + Orthophosphate
UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + MurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)-diphospho-undecaprenol
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine
UDP-N-acetyl-D-galactosamine + alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + Globoside
1-Hydroxy-2-naphthoate + NADH + H+ + Oxygen <=> Naphthalene-1,2-diol + CO2 + NAD+ + H2O
2-C-Methyl-D-erythritol 4-phosphate + CTP <=> 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol + Diphosphate
4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ATP <=> 2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ADP
Formyl-L-methionyl peptide + H2O <=> Methionyl peptide + Formate
Pyruvate + D-Glyceraldehyde 3-phosphate <=> 1-Deoxy-D-xylulose 5-phosphate + CO2
2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol <=> 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate + CMP
14-Demethyllanosterol + NADP+ <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+
Lanosterol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Ergosterol + NADP+ <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADPH + H+
2-Hydroxy-2H-benzo[h]chromene-2-carboxylate <=> cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate
2-Carboxybenzaldehyde + NAD+ + H2O <=> Phthalate + NADH + H+
ATP + D-glycero-beta-D-manno-Heptose 1-phosphate <=> Diphosphate + ADP-D-glycero-beta-D-manno-heptose
Sedoheptulose 7-phosphate <=> D-glycero-beta-D-manno-Heptose 7-phosphate
ATP + D-glycero-beta-D-manno-Heptose 7-phosphate <=> ADP + D-glycero-beta-D-manno-Heptose 1,7-bisphosphate
D-glycero-beta-D-manno-Heptose 1,7-bisphosphate + H2O <=> D-glycero-beta-D-manno-Heptose 1-phosphate + Orthophosphate
cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O <=> 1-Hydroxy-2-naphthaldehyde + Pyruvate
1-Hydroxy-2-naphthaldehyde + NAD+ + H2O <=> 1-Hydroxy-2-naphthoate + NADH + H+
Phenanthrene-3,4-diol + Oxygen <=> 2-Hydroxy-2H-benzo[h]chromene-2-carboxylate
Sulfoacetaldehyde + Orthophosphate <=> Acetyl phosphate + Sulfite
Taurine + Pyruvate <=> Sulfoacetaldehyde + L-Alanine
Phenanthrene + Oxygen + NADH + H+ <=> Phenanthrene-9,10-oxide + H2O + NAD+
Phenanthrene + Oxygen + NADH + H+ <=> Phenanthrene-1,2-oxide + H2O + NAD+
Phenanthrene + Oxygen + NADH + H+ <=> 1-Phenanthrol + H2O + NAD+
Phenanthrene-1,2-oxide <=> 1-Phenanthrol
1-Phenanthrol + CH3-R <=> 1-Methoxyphenanthrene + R
Phenanthrene-9,10-oxide + H2O <=> trans-9(S),10(S)-Dihydrodiolphenanthrene
2,4,6/3,5-Pentahydroxycyclohexanone <=> D-2,3-Diketo 4-deoxy-epi-inositol + H2O
2-Deoxy-5-keto-D-gluconic acid + ATP <=> 2-Deoxy-5-keto-D-gluconic acid 6-phosphate + ADP
MurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)-diphospho-undecaprenol + UDP-N-acetyl-alpha-D-glucosamine <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + UDP
2-Methylbenzaldehyde + NADP+ + H2O <=> o-Toluate + NADPH + H+
3-Methylbenzaldehyde + NADP+ + H2O <=> m-Methylbenzoate + NADPH + H+
m-Methylbenzoate + NADH + Oxygen + H+ <=> 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+
Toluene + NADH + H+ + Oxygen <=> 4-Cresol + NAD+ + H2O
ATP + NAD+ <=> 3'-Keto-3'-deoxy-ATP + NADH + H+
3'-Keto-3'-deoxy-ATP <=> 3'-Keto-3'-deoxy-AMP + Diphosphate
3'-Keto-3'-deoxy-AMP <=> 3'-Amino-3'-deoxy-AMP
3'-Amino-3'-deoxy-AMP + L-Tyrosine <=> N6,N6,O-Tridemethylpuromycin-5'-phosphate
N6,N6,O-Tridemethylpuromycin-5'-phosphate + Acetyl-CoA <=> N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + CoA
N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine
N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-O-demethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine
N-Acetyl-O-demethylpuromycin-5'-phosphate <=> N-Acetyl-O-demethylpuromycin
N-Acetyl-O-demethylpuromycin + S-Adenosyl-L-methionine <=> N-Acetylpuromycin + S-Adenosyl-L-homocysteine
N-Acetylpuromycin + H2O <=> Puromycin + Acetate
Sulcatol + NAD+ <=> Sulcatone + NADH + H+
sn-Glycerol 1-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+
sn-Glycerol 1-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+
O-Phospho-4-hydroxy-L-threonine + NAD+ <=> 2-Amino-3-oxo-4-phosphonooxybutyrate + NADH + H+
1,5-Anhydro-D-glucitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+
L-Idonate + NAD+ <=> 5-Dehydro-D-gluconate + NADH + H+
L-Idonate + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+
3-Methylbutanol + NAD+ <=> 3-Methylbutanal + NADH + H+
3-Methylbutanol + NADP+ <=> 3-Methylbutanal + NADPH + H+
dTDP-D-fucose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-glucose + NADPH + H+
2-C-Methyl-D-erythritol 4-phosphate + NADP+ <=> 1-Deoxy-D-xylulose 5-phosphate + NADPH + H+
(R)-2-Hydroxypropyl-CoM + NAD+ <=> 2-Oxopropyl-CoM + NADH + H+
(S)-2-Hydroxypropyl-CoM + NAD+ <=> 2-Oxopropyl-CoM + NADH + H+
Lophenol + NADP+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + NADPH + H+
GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
(S)-3-Sulfolactate + NAD+ <=> 3-Sulfopyruvate + NADH + H+
(S)-3-Sulfolactate + NADP+ <=> 3-Sulfopyruvate + NADPH + H+
Adenosine + 2 Oxygen + H2O <=> 9-Riburonosyladenine + 2 Hydrogen peroxide
Adenosine + Oxygen <=> 5'-Dehydroadenosine + Hydrogen peroxide
5'-Dehydroadenosine + Oxygen + H2O <=> 9-Riburonosyladenine + Hydrogen peroxide
Mannitol + Oxygen <=> D-Mannose + Hydrogen peroxide
4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O <=> Vanillate + NADH + H+
Coniferyl aldehyde + H2O + NAD+ <=> Ferulate + NADH + H+
Coniferyl aldehyde + H2O + NADP+ <=> Ferulate + NADPH + H+
Dihydrozeatin + NADP+ <=> Zeatin + NADPH + H+
Lathosterol + NADP+ <=> 5alpha-Cholesta-7,24-dien-3beta-ol + NADPH + H+
Glycine + 2 Acceptor <=> Hydrogen cyanide + CO2 + 2 Reduced acceptor
Reduced FMN + NAD+ <=> FMN + NADH + H+
Reduced FMN + NADP+ <=> FMN + NADPH + H+
Reduced riboflavin + NADP+ <=> Riboflavin + NADPH + H+
N6-(Delta2-Isopentenyl)-adenine + H2O + Acceptor <=> Adenine + 3-Methyl-2-butenal + Reduced acceptor
N,N-Dimethyl-1,4-phenylenediamine + Aniline + 2 NADP+ <=> para-(Dimethylamino)azobenzene + 2 NADPH + 2 H+
Ammonia + 2 H2O + 6 Ferricytochrome c <=> Nitrite + 6 Ferrocytochrome c + 6 H+
Coenzyme M + Acetoacetate + NADP+ <=> 2-Oxopropyl-CoM + CO2 + NADPH + H+
CoA + Glutathione + NADP+ <=> CoA-glutathione + NADPH + H+
2 Mycothiol + NAD+ <=> Mycothione + NADH + H+
2 Mycothiol + NADP+ <=> Mycothione + NADPH + H+
AMP + Sulfite + Glutathione disulfide <=> Adenylyl sulfate + 2 Glutathione
Linoleate + Oxygen <=> (9Z,12Z)-(11S)-11-Hydroperoxyoctadeca-9,12-dienoic acid
3-Hydroxy-1H-quinolin-4-one + Oxygen <=> Formylanthranilate + CO
3-Hydroxy-2-methyl-1H-quinolin-4-one + Oxygen <=> N-Acetylanthranilate + CO
Cl- + Oxygen <=> Chlorous acid
Phytanoyl-CoA + 2-Oxoglutarate + Oxygen <=> 2-Hydroxyphytanoyl-CoA + Succinate + CO2
Leucocyanidin + 2-Oxoglutarate + Oxygen <=> Taxifolin + Succinate + CO2 + H2O
2 Nitric oxide + 2 Oxygen + NADH + H+ <=> 2 Nitrate + NAD+
2 Nitric oxide + 2 Oxygen + NADPH + H+ <=> 2 Nitrate + NADP+
Quinine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3-Hydroxyquinine + [Oxidized NADPH---hemoprotein reductase] + H2O
(E)-4-Hydroxyphenylacetaldehyde oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-4-Hydroxymandelonitrile + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Propylene + NADH + H+ + Oxygen <=> (2R)-1,2-Epoxypropane + NAD+ + H2O
Propylene + NADH + H+ + Oxygen <=> (S)-1,2-Epoxypropane + NAD+ + H2O
Obtusifoliol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
(S)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3'-Hydroxy-N-methyl-(S)-coclaurine + [Oxidized NADPH---hemoprotein reductase] + H2O
4alpha-Hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Ferricytochrome b5 + 2 H2O
3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + 2 Ferricytochrome b5 + H2O
Acetone + HCO3- + 2 ATP + 3 H2O <=> Acetoacetate + 2 AMP + 4 Orthophosphate
Choline + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Betaine aldehyde hydrate + H2O + 2 Oxidized ferredoxin
Linoleate + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Crepenynate + 2 Ferricytochrome b5 + 2 H2O
7-O-Methylluteone + NADPH + H+ + Oxygen <=> Dihydrofurano derivative + NADP+ + H2O
Thiophene-2-carbonyl-CoA + Reduced acceptor + Oxygen <=> 5-Hydroxythiophene-2-carbonyl-CoA + Acceptor + H2O
Reduced rubredoxin + Superoxide + 2 H+ <=> Oxidized rubredoxin + Hydrogen peroxide
Ferulate + CoA + ATP <=> Feruloyl-CoA + Products of ATP breakdown
Ethylbenzene + H2O + Acceptor <=> (S)-1-Phenylethanol + Reduced acceptor
Phosphonic acid + NAD+ + H2O <=> Orthophosphate + NADH + H+
Arsenate ion + Glutaredoxin <=> Arsenite + Glutaredoxin disulfide
Methylarsonate + 2 Glutathione <=> Methanearsonous acid + Glutathione disulfide + H2O
Dopamine + Secologanin <=> Deacetylipecoside + H2O
Dopamine + Secologanin <=> Deacetylisoipecoside + H2O
Arsenite + H2O + 2 Oxidized azurin <=> Arsenate ion + 2 Reduced azurin + 2 H+
Arsenite + Acceptor <=> Arsenate ion + Reduced acceptor
Trichloroethene + Cl- + Acceptor <=> Tetrachloroethene + Reduced acceptor
S-Adenosyl-L-methionine + 2,4,6-Trichlorophenol <=> S-Adenosyl-L-homocysteine + 2,4.6-Trichloroanisole
S-Adenosyl-L-methionine + Arsenite <=> S-Adenosyl-L-homocysteine + Methylarsonate
S-Adenosyl-L-methionine + Methanearsonous acid <=> S-Adenosyl-L-homocysteine + Cacodylate
S-Adenosyl-L-methionine + 3'-Demethylstaurosporine <=> S-Adenosyl-L-homocysteine + Staurosporine
threo-3-Hydroxy-L-aspartate <=> Oxaloacetate + Ammonia
S-Adenosyl-L-methionine + (-)-Jasmonic acid <=> S-Adenosyl-L-homocysteine + Methyl jasmonate
S-Adenosyl-L-methionine + Cycloartenol <=> S-Adenosyl-L-homocysteine + (24R)-24-Methylcycloart-25-en-3-beta-ol
(R)-2-Hydroxypropyl-CoM <=> (2R)-1,2-Epoxypropane + Coenzyme M
(S)-2-Hydroxypropyl-CoM <=> (S)-1,2-Epoxypropane + Coenzyme M
S-Adenosyl-L-methionine + trans-Aconitate <=> S-Adenosyl-L-homocysteine + (E)-3-(Methoxycarbonyl)pent-2-enedioate
S-Adenosyl-L-methionine + trans-Aconitate <=> S-Adenosyl-L-homocysteine + (E)-2-(Methoxycarbonylmethyl)butenedioate
Geranyl diphosphate <=> (-)-alpha-Pinene + Diphosphate
Geranyl diphosphate <=> (-)-beta-Pinene + Diphosphate
alpha,alpha'-Trehalose 6-phosphate + Orthophosphate <=> D-Glucose 6-phosphate + beta-D-Glucose 1-phosphate
GDP-mannose + 3-Phospho-D-glycerate <=> GDP + 2-(alpha-D-Mannosyl)-3-phosphoglycerate
UDP-glucose + Hydroquinone <=> UDP + Arbutin
N-Cyclohexylformamide <=> Cyclohexyl isocyanide + H2O
Feruloyl-CoA + H2O <=> 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA
4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA
3-Sulfopyruvate <=> Sulfoacetaldehyde + CO2
UDP-glucose + Sulfite <=> UDP-6-sulfoquinovose + H2O
S-Adenosyl-L-methionine + 24-Methylenelophenol <=> S-Adenosyl-L-homocysteine + 24-Ethylidenelophenol
Diphospho-myo-inositol polyphosphate + H2O <=> myo-Inositol polyphosphate + Orthophosphate
3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> 4-Hydroxymandelate + CO2
5-PP-InsP5 + H2O <=> Phytic acid + Orthophosphate
Thiocyanate + 2 H2O <=> Carbonyl sulfide + Ammonia + HO-
Maleimide + H2O <=> Maleamate
N-Carbamoyl-L-amino acid + H2O <=> L-Amino acid + Ammonia + CO2
(R)-Mandelamide + H2O <=> (R)-Mandelate + Ammonia
Limonene-1,2-epoxide + H2O <=> Limonene-1,2-diol
6-O-(beta-D-Xylopyranosyl)-beta-D-glucopyranoside + H2O <=> 6-O-(beta-D-Xylopyranosyl)-beta-D-glucopyranose + Alcohol
(2R)-O-Phospho-3-sulfolactate + H2O <=> (2R)-3-Sulfolactate + Orthophosphate
2-(alpha-D-Mannosyl)-3-phosphoglycerate + H2O <=> 2-O-(alpha-D-Mannosyl)-D-glycerate + Orthophosphate
2-(alpha-D-Glucosyl)-sn-glycerol 3-phosphate + H2O <=> 2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate
3-(Acyloxy)acyl group of bacterial toxin + 2 H2O <=> 3-Hydroxyacyl group of bacterial toxin + 2 Fatty acid
Cutin + H2O <=> Cutin monomer
CDP-diacylglycerol + Choline <=> CMP + Phosphatidylcholine
ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Poly[(R)-3-hydroxyoctanoate]n + H2O <=> Poly[(R)-3-hydroxyoctanoate]n + Poly[(R)-3-hydroxyoctanoate]x
Poly[(R)-3-hydroxybutanoate]n-x + H2O <=> Poly[(R)-3-hydroxybutanoate]n-x + Poly[(R)-3-hydroxybutanoate]x
3'-Phosphoadenylyl sulfate + Heparan sulfate alpha-D-glucosaminide <=> Adenosine 3',5'-bisphosphate + [Heparan sulfate]-glucosamine 3-sulfate
ATP + Phytic acid <=> ADP + 1-Diphosinositol pentakisphosphate
ATP + D-myo-Inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-Inositol 1,4,5,6-tetrakisphosphate
ATP + 1D-myo-Inositol 1,4,5,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
ATP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
ATP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
ADP + D-Glucose <=> AMP + D-Glucose 6-phosphate
ADP + D-Fructose 6-phosphate <=> AMP + D-Fructose 1,6-bisphosphate
ATP + Deoxynucleoside <=> ADP + Deoxynucleoside 5'-phosphate
Sirohydrochlorin + Cobalt ion <=> Cobalt-sirohydrochlorin + 2 H+
Cobalt-sirohydrochlorin + S-Adenosyl-L-methionine <=> Cobalt-factor III + S-Adenosyl-L-homocysteine
Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine
Cobalt-precorrin 4 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 5A + S-Adenosyl-L-homocysteine
Cobalt-precorrin 5 + S-Adenosyl-L-methionine + H2O <=> Cobalt-precorrin 6 + S-Adenosyl-L-homocysteine + Acetaldehyde
Cobalt-precorrin 6 + NADH + H+ <=> Cobalt-dihydro-precorrin 6 + NAD+
Cobalt-dihydro-precorrin 6 + 2 S-Adenosyl-L-methionine <=> Cobalt-precorrin 8 + 2 S-Adenosyl-L-homocysteine + CO2
Cobalt-precorrin 8 <=> Cobyrinate
Cobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Cob(II)yrinate a,c diamide + 2 L-Glutamate + 2 ADP + 2 Orthophosphate
Mannan + H2O <=> D-Mannose + Mannan
Biliverdin + 4 Reduced ferredoxin <=> (3Z)-Phycocyanobilin + 4 Oxidized ferredoxin
Biliverdin + Reduced ferredoxin <=> 15,16-Dihydrobiliverdin + Oxidized ferredoxin
15,16-Dihydrobiliverdin + Reduced ferredoxin <=> (3Z)-Phycoerythrobilin + Oxidized ferredoxin
Protein N(pi)-phospho-L-histidine + D-Sorbitol <=> Protein histidine + Sorbitol 6-phosphate
Inosine + Oxygen <=> 9-Riburonosylhypoxanthine + H2O
2 5'-Oxoinosine + Oxygen <=> 2 9-Riburonosylhypoxanthine
2-Keto-D-gluconic acid + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+
4,21-Dehydrocorynantheine aldehyde <=> 4,21-Dehydrogeissoschizine
Polyneuridine aldehyde + H2O <=> 16-Epivellosimine + CO2 + Methanol
16-Epivellosimine <=> Vellosimine
10-Deoxysarpagine + NADP+ <=> Vellosimine + NADPH + H+
10-Deoxysarpagine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Sarpagine + [Oxidized NADPH---hemoprotein reductase] + H2O
Geissoschizine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Polyneuridine aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
2-Hydroxy-vitamin K + Oxidized dithiothreitol <=> Vitamin K1 epoxide + Dithiothreitol
Xylitol + NAD+ <=> L-Xylulose + NADH + H+
7-Deoxyloganate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Loganate + [Oxidized NADPH---hemoprotein reductase] + H2O
Loganate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Secologanate + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
S-Adenosyl-L-methionine + Secologanate <=> S-Adenosyl-L-homocysteine + Secologanin
Glycocholate + H2O <=> Cholic acid + Glycine
3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + 2 H+ <=> Deoxycholic acid
O-Phospho-4-hydroxy-L-threonine + NAD+ <=> 3-Amino-2-oxopropyl phosphate + NADH + H+ + CO2
3-Amino-2-oxopropyl phosphate + 1-Deoxy-D-xylulose 5-phosphate <=> Pyridoxine phosphate + Orthophosphate + 2 H2O
Pyridoxamine + 2-Oxoglutarate <=> Pyridoxal + D-Glutamate
Glycolaldehyde + 2-Oxobutanoate + Alanine <=> Pyridoxine
Phenylacetyl-CoA + Glycine <=> Phenylacetylglycine + CoA
Ethylene oxide + H2O <=> Ethylene glycol
Phenanthrene + NADH + H+ + Oxygen <=> (+)-cis-3,4-Dihydrophenanthrene-3,4-diol + NAD+
Strictosidine aglycone <=> Dialdehyde
Dialdehyde + H+ <=> 4,21-Dehydrocorynantheine aldehyde + H2O
4,21-Dehydrogeissoschizine <=> Cathenamine
Cathenamine + NADPH + H+ <=> Ajmalicine + NADP+
Cathenamine + NADPH + H+ <=> Tetrahydroalstonine + NADP+
Ajmalicine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Serpentine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O + 2 H+
L-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate
4,21-Dehydrogeissoschizine <=> Stemmadenine
Stemmadenine <=> Tabersonine
Stemmadenine <=> Catharanthine
Tabersonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16-Hydroxytabersonine + [Oxidized NADPH---hemoprotein reductase] + H2O
16-Methoxytabersonine + H2O <=> 16-Methoxy-2,3-dihydro-3-hydroxytabersonine
Desacetoxyvindoline + 2-Oxoglutarate + Oxygen <=> Deacetylvindoline + Succinate + CO2
Vindoline + Catharanthine <=> 3',4'-Anhydrovinblastine
3',4'-Anhydrovinblastine <=> Vinblastine
Vinblastine <=> Vincristine
D-Alanine + H2O + Oxygen <=> Pyruvate + Ammonia + Hydrogen peroxide
Sarcosine + H2O + Oxygen <=> Glyoxylate + Methylamine + Hydrogen peroxide
N-Ethylglycine + H2O + Oxygen <=> Glyoxylate + Ethylamine + Hydrogen peroxide
2-Hydroxy-cis-hex-2,4-dienoate + H2O <=> 4-Hydroxy-2-oxohexanoic acid
2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + H2O <=> Formate + 2-Hydroxy-cis-hex-2,4-dienoate
Tabersonine + NADPH + H+ + Oxygen <=> Lochnericine + NADP+ + H2O
Lochnericine <=> Horhammericine
Tabersonine <=> Horhammericine
Tabersonine <=> Minovincinine
Minovincinine + Acetyl-CoA <=> Echitovenine + CoA
19-Hydroxytabersonine <=> Horhammericine
Tabersonine <=> 19-Hydroxytabersonine
4,21-Dehydrogeissoschizine <=> 19-epi-Cathenamine
19-epi-Cathenamine + NADPH + H+ <=> 19-epi-Ajmalicine + NADP+
2 Reduced [2Fe-2S] ferredoxin + NAD+ + H+ <=> 2 Oxidized [2Fe-2S] ferredoxin + NADH
Acetyl-CoA + 16-Epivellosimine <=> CoA + Vinorine
Vinorine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Vomilenine + [Oxidized NADPH---hemoprotein reductase] + H2O
1,2-Dihydrovomilenine + NADP+ <=> Vomilenine + NADPH + H+
17-O-Acetylnorajmaline + NADP+ <=> 1,2-Dihydrovomilenine + NADPH + H+
17-O-Acetylnorajmaline + H2O <=> Norajmaline + Acetate
Norajmaline + S-Adenosyl-L-methionine <=> Ajmaline + S-Adenosyl-L-homocysteine
UDP-glucose + Vomilenine <=> UDP + Raucaffricine
1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + 2 Reduced ferredoxin + 2 H+ <=> Isopentenyl diphosphate + 2 Oxidized ferredoxin + H2O
16-Hydroxytabersonine + S-Adenosyl-L-methionine <=> 16-Methoxytabersonine + S-Adenosyl-L-homocysteine + H+
Tabersonine <=> Lochnerinine
Deacetylipecoside <=> Demethylalangiside
Demethylalangiside <=> Alangiside
Deacetylisoipecoside <=> Demethylisoalangiside
Demethylisoalangiside <=> Isoalangiside
Protoemetine <=> Tubulosine
Protoemetine + Tryptamine <=> Deoxytubulosine
Deoxytubulosine <=> Alangimarckine
Protoemetine <=> Ankorine
Loganate <=> 10-Deoxygeniposidic acid
10-Deoxygeniposidic acid <=> Geniposidic acid
Geniposidic acid <=> Asperuloside
UDP-N-acetyl-D-glucosamine + G00025 <=> UDP + G00209
UDP-N-acetyl-D-glucosamine + Galactosylgloboside <=> UDP + G00102
UDP-D-galactose + G00102 <=> UDP + G00103
GDP-L-fucose + G00103 <=> GDP + G00104
CMP-N-acetylneuraminate + G00393 <=> CMP + G00251
CMP-N-acetylneuraminate + G00837 <=> CMP + G00251
UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen
UDP-D-galactose + Tn antigen <=> UDP + T antigen
UDP-N-acetyl-D-glucosamine + Tn antigen <=> UDP + G00028
UDP-N-acetyl-D-glucosamine + Tn antigen <=> UDP + G00031
CMP-N-acetylneuraminate + Tn antigen <=> CMP + Sialyl-Tn antigen
UDP-N-acetyl-D-glucosamine + T antigen <=> UDP + G00025
CMP-N-acetylneuraminate + T antigen <=> CMP + G00026
CMP-N-acetylneuraminate + G00026 <=> CMP + G00027
UDP-N-acetyl-D-glucosamine + G00028 <=> UDP + G00029
UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143
G00143 + H2O <=> G00144 + Acetate
G00144 + Palmitoyl-CoA <=> G00145 + CoA
Dolichyl phosphate D-mannose + G00145 <=> Dolichyl phosphate + G00146
Dolichyl phosphate D-mannose + G00148 <=> Dolichyl phosphate + G00149
Phosphatidylethanolamine + G00140 <=> 1,2-Diacyl-sn-glycerol + G00141
Phosphatidylethanolamine + G00141 <=> 1,2-Diacyl-sn-glycerol + G00151
UDP-D-xylose + [Protein]-L-serine <=> UDP + G00154
UDP-D-galactose + G00154 <=> UDP + G00155
UDP-D-galactose + G00155 <=> UDP + G00156
UDP-D-glucuronate + G00156 <=> UDP + G00157
UDP-N-acetyl-D-galactosamine + G00157 <=> UDP + G00158
UDP-N-acetyl-D-glucosamine + G00157 <=> UDP + G00162
UDP-D-glucuronate + G00158 <=> UDP + G00159
UDP-N-acetyl-D-galactosamine + G00159 <=> UDP + G00160
UDP-D-glucuronate + G00160 <=> UDP + G00180
UDP-N-acetyl-D-galactosamine + G00180 <=> UDP + G00161
UDP-D-glucuronate + G00162 <=> UDP + G00163
UDP-N-acetyl-D-glucosamine + G00163 <=> UDP + G00164
CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + GM3
UDP-N-acetyl-D-galactosamine + Lactosylceramide <=> UDP + GA2
UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + GM2
CMP-N-acetylneuraminate + GM3 <=> CMP + GD3
UDP-D-galactose + GM2 <=> UDP + GM1
CMP-N-acetylneuraminate + GM1 <=> CMP + GD1a
CMP-N-acetylneuraminate + GD1a <=> CMP + GT1a
GDP-L-fucose + GM1 <=> GDP + Fucosyl-GM1
CMP-N-acetylneuraminate + GD1a <=> CMP + GT1aalpha
UDP-N-acetyl-D-galactosamine + GD3 <=> UDP + GD2
CMP-N-acetylneuraminate + GD3 <=> CMP + GT3
UDP-D-galactose + GD2 <=> UDP + GD1b
CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b
CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1b
CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1balpha
UDP-N-acetyl-D-galactosamine + GT3 <=> UDP + GT2
UDP-D-galactose + GT2 <=> UDP + GT1c
CMP-N-acetylneuraminate + GT1c <=> CMP + GQ1c
CMP-N-acetylneuraminate + GQ1c <=> CMP + GP1c
UDP-D-galactose + GA2 <=> UDP + GA1
CMP-N-acetylneuraminate + GA1 <=> CMP + GM1b
CMP-N-acetylneuraminate + GM1b <=> CMP + GD1c
CMP-N-acetylneuraminate + GM1b <=> CMP + GD1a
UDP-D-galactose + Lactosylceramide <=> UDP + Globotriaosylceramide
H2O + Globotriaosylceramide <=> D-Galactose + Lactosylceramide
UDP-N-acetyl-D-galactosamine + Globotriaosylceramide <=> UDP + Globoside
H2O + Globoside <=> N-Acetyl-D-galactosamine + Globotriaosylceramide
UDP-D-galactose + Globoside <=> UDP + Galactosylgloboside
UDP-N-acetyl-D-galactosamine + Globoside <=> UDP + Forssman antigen, IV3GalNAca-Gb4Cer
H2O + Forssman antigen, IV3GalNAca-Gb4Cer <=> N-Acetyl-D-galactosamine + Globoside
CMP-N-acetylneuraminate + Galactosylgloboside <=> CMP + Monosialylgalactosylgloboside
GDP-L-fucose + Galactosylgloboside <=> GDP + Globo-H
UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol
UDP-N-acetyl-D-glucosamine + N-Acetyl-D-glucosaminyldiphosphodolichol <=> UDP + N,N'-Chitobiosyldiphosphodolichol
UDP-N-acetyl-D-glucosamine + Lactosylceramide <=> UDP + Lc3Cer
GDP-D-mannose + N,N'-Chitobiosyldiphosphodolichol <=> GDP + G00003
GDP-D-mannose + G00003 <=> GDP + G00004
UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + nLc7Cer
UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + nLc5Cer
Protein asparagine + G00008 <=> Dolichyl diphosphate + G00009
UDP-D-galactose + Lc3Cer <=> UDP + Paragloboside
UDP-D-galactose + Paragloboside <=> UDP + nLc5Cer
H2O + G00009 <=> beta-D-Glucose + G00171
H2O + G00171 <=> D-Glucose + G00010
H2O + G00010 <=> D-Glucose + G00011
UDP-N-acetyl-D-glucosamine + G00012 <=> UDP + G00013
G00013 + 2 H2O <=> G00014 + 2 alpha-D-Mannose
UDP-N-acetyl-D-glucosamine + G00014 <=> UDP + G00015
UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G00019
UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G00020
GDP-L-fucose + G00015 <=> GDP + G00016
2 UDP-D-galactose + G00016 <=> 2 UDP + G00017
2 CMP-N-acetylneuraminate + G00017 <=> 2 CMP + DS 3
UDP-N-acetyl-D-glucosamine + G00020 <=> UDP + G00021
UDP-N-acetyl-D-glucosamine + G00021 <=> UDP + G00022
GA1 + H2O <=> GA2 + D-Galactose
CMP-N-acetylneuraminate + GT1a <=> CMP + GQ1b
GT1b + N-Acetylneuraminate <=> GQ1b + H2O
GT1b + H2O <=> GD1b + N-Acetylneuraminate
Lactosylceramide + N-Acetylneuraminate <=> GM3 + H2O
CMP-N-acetylneuraminate + GD1a <=> CMP + GT1b
GA2 + H2O <=> Lactosylceramide + N-Acetyl-D-galactosamine
CMP-N-acetylneuraminate + GA1 <=> CMP + GM1
GM2 + H2O <=> GM3 + N-Acetyl-D-galactosamine
CMP-N-acetylneuraminate + GM1 <=> CMP + GD1b
UDP-D-galactose + Lc3Cer <=> UDP + Lc4Cer
CMP-N-acetylneuraminate + GA2 <=> CMP + GM2
CMP-N-acetylneuraminate + GM2 <=> CMP + GD2
GM1 + H2O <=> GM2 + D-Galactose
UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + G00176
GM2 + H2O <=> GA2 + N-Acetylneuraminate
UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + G00174
UDP-N-acetyl-D-glucosamine + G00172 <=> UDP + G07376
GDP-L-fucose + G00015 <=> GDP + G00178
UDP-D-xylose + G00015 <=> UDP + G00179
1,3-beta-D-Glucan(n) + Orthophosphate <=> 1,3-beta-D-Glucan(n-1) + D-Glucose 1-phosphate
1,3-beta-D-Glucan(n) + UDP-D-glucose <=> 1,3-beta-D-Glucan(n+1) + UDP
UDP-D-galactose + G00077 <=> UDP + iso-nLc8Cer
1,4-beta-D-Glucan(n) + Orthophosphate <=> 1,4-beta-D-Glucan(n-1) + D-Glucose 1-phosphate
1,4-beta-D-Glucan(n) + UDP-D-glucose <=> 1,4-beta-D-Glucan(n+1) + UDP
GDP-L-fucose + Paragloboside <=> GDP + IV2Fuc-nLc4Cer
GDP-L-fucose + Paragloboside <=> GDP + III3Fuc-nLc4Cer
CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-3-paragloboside
GDP-L-fucose + nLc5Cer <=> GDP + Type II B antigen
beta-1,4-Poly-N-acetyl-D-glucosamine(n) + UDP-N-acetyl-D-glucosamine <=> beta-1,4-Poly-N-acetyl-D-glucosamine(n+1) + UDP
UDP-D-galactose + IV2Fuc-nLc4Cer <=> UDP + Type II B antigen
1,4-beta-D-Glucan(n+1) + GDP <=> 1,4-beta-D-Glucan(n) + GDP-glucose
GDP-L-fucose + G00057 <=> GDP + Type IIIH glycolipid
CMP-N-acetylneuraminate + Sialyl-3-paragloboside <=> CMP + 3',8'-LD1
UDP-D-galactose + nLc5Cer <=> UDP + nLc6Cer
Sucrose + Orthophosphate <=> D-Fructose + D-Glucose 1-phosphate
GDP-L-fucose + nLc6Cer <=> GDP + VI2Fuc-nLc6
UDP-D-glucose + D-Fructose <=> Sucrose + UDP
CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI3NeuAc-nLc6Cer
GDP-L-fucose + nLc6Cer <=> GDP + V3Fuc-nLc6Cer
GDP-L-fucose + nLc8Cer <=> GDP + G00084
Maltose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate
GDP-L-fucose + G00073 <=> GDP + G00074
Galactinol + Raffinose <=> Stachyose + myo-Inositol
UDP-D-glucose + D-Glucose 6-phosphate <=> UDP + Trehalose 6-phosphate
Trehalose 6-phosphate + Orthophosphate <=> D-Glucose 6-phosphate + beta-D-Glucose 1-phosphate
1,3-alpha-D-Glucan(n) + UDP-D-glucose <=> 1,3-alpha-D-Glucan(n+1) + UDP
beta-D-Mannosylphosphodecaprenol + 1,6-alpha-D-Mannosyloligosaccharide <=> Decaprenol phosphate + 1,6-alpha-D-Mannosyl-1,6-alpha-D-mannosyloligosaccharide
UDP-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
UDP-glucose + Indoxyl <=> UDP + Indican
1,4-alpha-D-Glucan(n) + ADP-glucose <=> 1,4-alpha-D-Glucan(n+1) + ADP
1,4-alpha-D-Glucan(n) + Orthophosphate <=> 1,4-alpha-D-Glucan(n-1) + D-Glucose 1-phosphate
1,4-alpha-D-Glucan(n) + UDP-D-glucose <=> 1,4-alpha-D-Glucan(n+1) + UDP
1,4-alpha-D-Glucan(n) + Sucrose <=> 1,4-alpha-D-Glucan(n+1) + D-Fructose
Trehalose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate
3-Deoxyoctulosonyl-lipopolysaccharide + H2O <=> 3-Deoxy-D-manno-octulosonate + Lipopolysaccharide
UDP-D-galactose + N-Acetyl-D-glucosamine <=> N-Acetyllactosamine + UDP
Cellobiose + Orthophosphate <=> D-Glucose 1-phosphate + D-Glucose
Lacto-N-biose + Orthophosphate <=> alpha-D-Galactose 1-phosphate + N-Acetyl-D-glucosamine
Laminaribiose + Orthophosphate <=> D-Glucose + D-Glucose 1-phosphate
G10497(n) + Sucrose <=> G10497(n+1) + D-Glucose
2 D-Glucose 1-phosphate <=> Maltose + 2 Orthophosphate
UDP-D-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
5-Hydroxyisourate + H+ + H2O <=> (R)(-)-Allantoin + CO2
5-Hydroxyisourate + H+ + H2O <=> (S)-Allantoin + CO2
1,6-alpha-D-Glucan(n) + Sucrose <=> 1,6-alpha-D-Glucan(n+1) + D-Fructose
UDP-D-galactose + D-Glucose <=> Lactose + UDP
n UDP-N-acetyl-D-glucosamine + n UDP-D-glucuronate <=> Hyaluronic acid + 2n UDP
1,4-alpha-D-Glucan + n D-Glucose <=> n Maltose
Raffinose + H2O <=> D-Galactose + Sucrose
Galactinol + Sucrose <=> myo-Inositol + Raffinose
Pectic acid(n) + UDP-D-galacturonate <=> Pectic acid(n+1) + UDP
UDP-D-glucose + D-Fructose 6-phosphate <=> UDP + Sucrose 6'-phosphate
beta-D-Mannosylphosphodecaprenol + 1,6-alpha-D-Mannosyloligosaccharide(n) <=> Decaprenol phosphate + 1,6-alpha-D-Mannosyloligosaccharide(n+1)
GDP-L-fucose + Sialyl-3-paragloboside <=> GDP + IV3NeuAc,III3Fuc-nLc4Cer
GDP-L-fucose + VI2Fuc-nLc6 <=> GDP + G00081
1,4-beta-D-Glucan(n+1) + H2O <=> 1,4-beta-D-Glucan(n) + beta-D-Glucose
1,3-beta-D-Glucan(n+1) + H2O <=> 1,3-beta-D-Glucan(n) + alpha-D-Glucose
D-Glucose + G10499(n+1) <=> Sucrose + G10499(n)
Isomaltose + H2O <=> alpha-D-Glucose + D-Glucose
beta-1,4-Poly-N-acetyl-D-glucosamine(n+1) + H2O <=> N-Acetyl-D-glucosamine + beta-1,4-Poly-N-acetyl-D-glucosamine(n)
beta-1,4-Poly-N-acetyl-D-glucosamine(n+2) + H2O <=> Chitobiose + beta-1,4-Poly-N-acetyl-D-glucosamine(n)
Xylan(n) + UDP-D-xylose <=> Xylan(n+1) + UDP
Maltose + H2O <=> 2 alpha-D-Glucose
GDP-L-fucose + iso-nLc8Cer <=> GDP + Monofucosyllactoisooctaosylceramide
GDP-L-fucose + Monofucosyllactoisooctaosylceramide <=> GDP + G00079
Sucrose + H2O <=> D-Fructose + D-Glucose
Sucrose + H2O <=> beta-D-Fructose + alpha-D-Glucose
GDP-L-fucose + iso-nLc8Cer <=> GDP + Monofucosyllactoisooctaosylceramide
GDP-L-fucose + Monofucosyllactoisooctaosylceramide <=> GDP + G00079
Melibiose + H2O <=> D-Galactose + D-Glucose
Cellobiose + H2O <=> 2 beta-D-Glucose
Galactinol + H2O <=> myo-Inositol + D-Galactose
Galabiosylceramide + H2O <=> Galactosylceramide + D-Galactose
GDP-L-fucose + IV2Fuc-nLc4Cer <=> GDP + III3,IV2Fuc-nLc4Cer
Manninotriose + H2O <=> D-Galactose + Melibiose
UDP-D-galactose + nLc7Cer <=> UDP + nLc8Cer
Lactose + H2O <=> alpha-D-Glucose + D-Galactose
Lactosylceramide + H2O <=> Glucosylceramide + D-Galactose
Raffinose + H2O <=> Melibiose + D-Fructose
Stachyose + H2O <=> Manninotriose + D-Fructose
Sucrose 6'-phosphate + H2O <=> beta-D-Fructose + alpha-D-Glucose 6-phosphate
Trehalose + H2O <=> 2 D-Glucose
Cellobiose + H2O <=> 2 D-Glucose
Cellotriose + H2O <=> Cellobiose + D-Glucose
Cellotetraose + H2O <=> Cellotriose + D-Glucose
Cellopentaose + H2O <=> Cellotetraose + D-Glucose
Celloheptaose + H2O <=> Cellohexaose + D-Glucose
Cellohexaose + H2O <=> Cellopentaose + D-Glucose
Lactose 6'-phosphate + H2O <=> beta-D-Glucose + D-Galactose 6-phosphate
G10518 + H2O <=> D-Glucose + D-Glucose 6-phosphate
H2O + Trehalose 6-phosphate <=> D-Glucose + D-Glucose 6-phosphate
Lactose + H2O <=> D-Glucose + D-Galactose
H2O + Maltose 6'-phosphate <=> D-Glucose + D-Glucose 6-phosphate
Lc4 + H2O <=> Lacto-N-biose + Lactose
(+)-trans-Carveol + NAD+ <=> (+)-(S)-Carvone + NADH + H+
G10523 + H2O <=> 6-Deoxy-L-galactose + Methyl beta-D-galactoside
(R)-Limonene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (+)-trans-Carveol + [Oxidized NADPH---hemoprotein reductase] + H2O
Geranyl diphosphate <=> (R)-Limonene + Diphosphate
Lactosylceramide + CMP-N-acetylneuraminate <=> GM3 + CMP
Galabiosylceramide + 3'-Phosphoadenylyl sulfate <=> Digalactosylceramide sulfate + Adenosine 3',5'-bisphosphate
alpha-Amino acid + H2O + Oxygen <=> 2-Oxo acid + Ammonia + Hydrogen peroxide
GDP-glucose + D-Glucose 6-phosphate <=> Trehalose 6-phosphate + GDP
L-Serine + NADP+ <=> 2-Aminomalonate semialdehyde + NADPH + H+
G00005 + GDP-D-mannose <=> G10526 + GDP
G10526 + GDP-D-mannose <=> G00006 + GDP
UDP-N-acetyl-D-mannosamine + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> G00177 + UDP
Sucrose + UDP-D-galactose <=> Planteose + UDP
alpha-Amino acid <=> 2-Oxo acid + Ammonia
alpha-Amino acid <=> 2,3-Ene acid + Ammonia
Amide + H2O <=> Carboxylate + Ammonia
2 Sucrose <=> 1-Kestose + D-Glucose
Amidine + H2O <=> Amide + Ammonia
2 Raffinose <=> G01504 + Sucrose
T antigen + H2O <=> G10607 + [Protein]-L-serine
Chitobiose + H2O <=> 2 N-Acetyl-D-glucosamine
Epimelibiose + H2O <=> D-Mannose + D-Galactose
G10530 + H2O <=> N,6-O-Disulfo-D-glucosamine + D-Glucuronate
3-Ketolactose + H2O <=> 3-Keto-beta-D-galactose + beta-D-Glucose
N-Acetyllactosamine + UDP-D-galactose <=> Linear B type 2 trisaccharide + UDP
Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O
1,6-alpha-D-Mannosyloligosaccharide(n+1) + H2O <=> D-Mannose + G10542(n)
G10540 + H2O <=> D-Mannose + G10542
G10541 + H2O <=> D-Mannose + G10542
Stachyose + H2O <=> Raffinose + D-Galactose
CMP-N-acetylneuraminate + Lc4Cer <=> CMP + 3'-isoLM1
Methylamine + Oxygen + H2O <=> Formaldehyde + Ammonia + Hydrogen peroxide
GDP-L-fucose + Lc4Cer <=> GDP + Fuc-Lc4Cer
GDP-L-fucose + Lc4Cer <=> GDP + IV2Fuc-Lc4Cer
G10544 + H2O <=> Starch + N-Acylsphingosine
Starch + H2O <=> 1,4-alpha-D-Glucan + alpha-D-Glucose
Cyclomaltodextrin + H2O <=> 1,4-alpha-D-Glucan
Bis-D-fructose 2',1:2,1'-dianhydride + H2O <=> Inulobiose
GDP-L-fucose + Type IA glycolipid <=> GDP + G00043
GDP-L-fucose + IV2Fuc-Lc4Cer <=> GDP + IV2Fuc,III4Fuc-Lc4Cer
GDP-L-fucose + Type IB glycolipid <=> GDP + G00040
GDP-L-fucose + 3'-isoLM1 <=> GDP + Fuc-3'-isoLM1
3beta-Hydroxy-5beta-pregnane-20-one + NADP+ <=> 5beta-Pregnane-3,20-dione + NADPH + H+
UDP-N-acetyl-D-galactosamine + IV2Fuc-Lc4Cer <=> UDP + Type IA glycolipid
UDP-D-galactose + IV2Fuc-Lc4Cer <=> UDP + Type IB glycolipid
UDP-D-galactose + Lc4Cer <=> UDP + G00038
GDP-L-fucose + G00038 <=> GDP + Type IB glycolipid
L-Allothreonine <=> Glycine + Acetaldehyde
G10551 + UDP-N-acetyl-D-glucosamine <=> G10550 + UDP
G10552 + UDP-N-acetyl-D-glucosamine <=> G10553 + UDP
G10556 + UDP-N-acetyl-D-glucosamine <=> G10555 + UDP
Chitosan(n+m) + H2O <=> Chitosan(n) + Chitosan(m)
ATP + Cellobiose <=> ADP + G10518
G10555 + G10557(n) <=> di-trans,poly-cis-Undecaprenyl diphosphate + G10557(n+1)
Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-g-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol <=> di-trans,poly-cis-Undecaprenyl diphosphate + [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-g-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol
G10553 + G10554(n) <=> di-trans,poly-cis-Undecaprenyl diphosphate + G10554(n+1)
(R,R)-Tartaric acid + NAD+ <=> 2-Hydroxy-3-oxosuccinate + NADH + H+
G10558 + UDP-D-glucose <=> G10559 + UDP
G10558 + UDP-N-acetyl-D-glucosamine <=> G10560 + UDP
G10497(m) + G10497(n) <=> G10497(m-1) + G10497(n+1)
1,6-alpha-D-Glucan(m) + 1,4-alpha-D-Glucan(n) <=> 1,6-alpha-D-Glucan(m+1) + 1,4-alpha-D-Glucan(n-1)
Starch + Orthophosphate <=> 1,4-alpha-D-Glucan + D-Glucose 1-phosphate
1,4-alpha-D-Glucan <=> Starch
UDP-N-acetyl-D-galactosamine + IV2Fuc-nLc4Cer <=> UDP + Type II A antigen
N-Acetyllactosamine + CMP-N-acetylneuraminate <=> G00255 + CMP
UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + G00077
UDP-D-galactose + VI2Fuc-nLc6 <=> UDP + G00083
UDP-N-acetyl-D-galactosamine + G00074 <=> UDP + Type IIIAb
UDP-D-galactose + G00072 <=> UDP + G00073
UDP-N-acetyl-D-galactosamine + VI2Fuc-nLc6 <=> UDP + G00072
Lumirhodopsin <=> Metarhodopsin
ent-Kaurene <=> Aconitine
ent-Kaurene <=> Veatchine
UDP-N-acetyl-D-galactosamine + Type IIIH glycolipid <=> UDP + Type IIIA glycolipid
UDP-D-galactose + Type II A antigen <=> UDP + G00057
Starch(n+1) + H2O <=> alpha-D-Glucose + Starch(n)
1,4-beta-D-Glucan(n+2) + H2O <=> 1,4-beta-D-Glucan(n) + Cellobiose
Pectic acid(n+1) + H2O <=> D-Galacturonate + Pectic acid(n)
G10534(n+1) + H2O <=> D-Galactose + G10534(n)
D-Xylose + Xylan(n) <=> Xylan(n+1) + H2O
1,3-beta-D-Glucan(n+1) + H2O <=> D-Glucose + 1,3-beta-D-Glucan(n)
H2O + G10499(n+m) <=> G10499(n) + G10499(m)
G10532(n+1) + H2O <=> D-Mannose + G10532(n)
G10535(n+1) + H2O <=> D-Fructose + G10535(n)
Starch(n+m) + H2O <=> Starch(n) + Starch(m)
UDP-D-galactose + G10534(n) <=> G10534(n+1) + UDP
Sucrose 6'-phosphate + H2O <=> Sucrose + Orthophosphate
GDP-D-mannose + G10532(n) <=> GDP + G10532(n+1)
UDP-D-galactose + myo-Inositol <=> UDP + Galactinol
CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-6-paragloboside
CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI6NeuAc-nLc6Cer
Sucrose <=> Palatinose
Maltose <=> Trehalose
Lactose + Acceptor <=> 3-Ketolactose + Reduced acceptor
GDP-L-fucose + V3Fuc-nLc6Cer <=> GDP + V3Fuc,III3Fuc-nLc6Cer
GDP-L-fucose + G00084 <=> GDP + G00085
2 trans,trans-Farnesyl diphosphate + NADPH + H+ <=> Squalene + 2 Diphosphate + NADP+
GDP-L-fucose + G00085 <=> GDP + G00086
D-Glucosamine + Chitosan(n) <=> Chitosan(n+1) + H2O
UDP-D-glucose + alpha-D-Glucose 6-phosphate <=> UDP + Trehalose 6-phosphate
GDP-L-fucose + G00081 <=> GDP + G00082
Trehalose 6-phosphate + H2O <=> Trehalose + Orthophosphate
Trehalose + Protein N(pi)-phospho-L-histidine <=> Trehalose 6-phosphate + Protein histidine
GDP-L-fucose + nLc6Cer <=> GDP + III3Fuc-nLc6Cer
CMP-N-acetylneuraminate + V3Fuc-nLc6Cer <=> CMP + G00091
Sucrose + FAD <=> 3-Ketosucrose + FADH2
Galactosylceramide + UDP-D-galactose <=> Galabiosylceramide + UDP
Protein N(pi)-phospho-L-histidine + Maltose <=> Protein histidine + Maltose 6'-phosphate
Protein N(pi)-phospho-L-histidine + Lactose <=> Protein histidine + Lactose 6'-phosphate
GDP-D-mannose + G00004 <=> GDP + G00005
Pectic acid(n+2) + H2O <=> G02614 + Pectic acid(n)
Pectic acid(n+2) <=> G10113 + Pectic acid(n)
beta-1,4-Poly-N-acetyl-D-glucosamine + n H2O <=> Chitosan + n Acetate
Hyaluronic acid <=> n Hyaluronan-derived disaccharide
1,4-alpha-D-Glucan(n+1) <=> G10589(n)
Cellobiose + Oxygen <=> G10590 + Hydrogen peroxide
Cellobiose <=> G01630
Cellobiose + Acceptor <=> G10590 + Reduced acceptor
Cellobiose + Quinone <=> G10590 + Hydroquinone
G10113 <=> 2 5-Dehydro-4-deoxy-D-glucuronate
Pectin + n H2O <=> n Methanol + Pectic acid
Acetyl-CoA + Maltose <=> CoA + Acetyl-maltose
GM1 + N-Acetylneuraminate <=> GD1a + H2O
2 I-Urobilinogen + Oxygen <=> 2 Urobilin + 2 H2O
2 L-Urobilinogen + Oxygen <=> 2 L-Urobilin + 2 H2O
D-Urobilinogen + 2 H+ <=> I-Urobilinogen
I-Urobilinogen + 4 H+ <=> L-Urobilinogen
Dolichyl phosphate D-mannose + G00006 <=> Dolichyl phosphate + G10595
Dolichyl phosphate D-mannose + G10595 <=> Dolichyl phosphate + G10596
Dolichyl phosphate D-mannose + G10596 <=> Dolichyl phosphate + G10597
Dolichyl phosphate D-mannose + G10597 <=> Dolichyl phosphate + G00007
Dolichyl D-glucosyl phosphate + G00007 <=> Dolichyl phosphate + G10598
Dolichyl D-glucosyl phosphate + G10598 <=> Dolichyl phosphate + G10599
Dolichyl D-glucosyl phosphate + G10599 <=> Dolichyl phosphate + G00008
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + Oxygen <=> 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + Oxygen <=> 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O
13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + Oxygen <=> Divinylprotochlorophyllide + NADP+ + 2 H2O
Magnesium protoporphyrin monomethyl ester + S-Adenosyl-L-methionine + H2O <=> 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine <=> 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine
13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine <=> Divinylprotochlorophyllide + 5'-Deoxyadenosine + L-Methionine
Divinylprotochlorophyllide + 2 H+ <=> Protochlorophyllide
Divinyl chlorophyllide a + NADPH + H+ <=> Chlorophyllide + NADP+
CMP-N-acetylneuraminate + G04854 <=> CMP + G04461
CMP-N-acetylneuraminate + G04461 <=> CMP + G04135
UDP-D-glucose + N-Acylsphingosine <=> UDP + Glucosylceramide
Glucosylceramide + UDP-D-galactose <=> Lactosylceramide + UDP
UDP-D-galactose + N-Acylsphingosine <=> UDP + Galactosylceramide
n UDP-D-galacturonate <=> n UDP + Pectin
3'-Phosphoadenylyl sulfate + Galactosylceramide <=> Adenosine 3',5'-bisphosphate + Sulfatide
Sulfatide + H2O <=> Galactosylceramide + Sulfate
Chlorophyllide + Oxidized ferredoxin + 2 ADP + 2 Orthophosphate <=> Protochlorophyllide + Reduced ferredoxin + 2 ATP + 2 H2O
H2O + 3'-LM1-NeuGc <=> N-Acylsphingosine + nLc4
Chlorophyllide + Phytyl diphosphate <=> Chlorophyll a + Diphosphate
3-Deoxy-D-manno-octulosonyl-lipid IV(A) + CMP-3-deoxy-D-manno-octulosonate <=> Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) + CMP
Divinyl chlorophyllide a + NADP+ <=> Divinylprotochlorophyllide + NADPH + H+
Divinyl chlorophyllide a <=> Divinylchlorophyll a
Divinylchlorophyll a <=> Chlorophyll a
2 Mycothiol + NAD+ <=> Mycothione + NADH + H+
2 Mycothiol + NADP+ <=> Mycothione + NADPH + H+
ent-Kaurene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
Kaur-16-en-18-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-al + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Kaur-16-en-18-al + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-oic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Kaur-16-en-18-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Gibberellin A12 aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6beta,7beta-Dihydroxykaurenoic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Gibberellin A12 aldehyde + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Gibberellin A12 + [Oxidized NADPH---hemoprotein reductase] + H2O
Geranylgeranyl diphosphate <=> Copalyl diphosphate
Copalyl diphosphate <=> Pimaradiene + Diphosphate
Copalyl diphosphate <=> (-)-Abietadiene + Diphosphate
Copalyl diphosphate <=> Levopimaradiene + Diphosphate
Copalyl diphosphate <=> Neoabietadiene + Diphosphate
Copalyl diphosphate <=> Palustradiene + Diphosphate
Geranylgeranyl diphosphate <=> Taxa-4(5),11(12)-diene + Diphosphate
Taxa-4(5),11(12)-diene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taxa-4(20),11(12)-dien-5alpha-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
Taxa-4(20),11(12)-dien-5alpha-ol + Acetyl-CoA <=> Taxa-4(20),11(12)-dien-5alpha-yl acetate + CoA
Taxa-4(20),11(12)-dien-5alpha-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taxa-4(20),11(12)-dien-5alpha,13alpha-diol + [Oxidized NADPH---hemoprotein reductase] + H2O
Taxa-4(20),11(12)-dien-5alpha-yl acetate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taxa-4(20),11(12)-dien-5alpha-acetoxy-10beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
10-Deacetyl-2-debenzoylbaccatin III + Benzoyl-CoA <=> 10-Deacetylbaccatin III + CoA
10-Deacetylbaccatin III + Acetyl-CoA <=> Baccatin III + CoA
Geranylgeranyl diphosphate <=> 9alpha-Copalyl diphosphate
9alpha-Copalyl diphosphate + H2O <=> Aphidicolan-16beta-ol + Diphosphate
9alpha-Copalyl diphosphate <=> Aphidicol-16-ene
9alpha-Copalyl diphosphate <=> Aphidicol-15-ene
Aphidicolan-16beta-ol <=> Aphidicolin
Aphidicol-16-ene <=> Aphidicolin
Taxa-4(20),11(12)-dien-5alpha,13alpha-diol <=> 10-Deacetyl-2-debenzoylbaccatin III
10beta,14beta-Dihydroxytaxa-4(20),11-dien-5alpha-yl acetate <=> 10-Deacetyl-2-debenzoylbaccatin III
Baccatin III <=> Paclitaxel
Geranylgeranyl diphosphate <=> Cembrene
Gibberellin A12 + 2-Oxoglutarate + Oxygen <=> Gibberellin A15 open lactone + Succinate + CO2
Gibberellin A15 open lactone + 2-Oxoglutarate + Oxygen <=> Gibberellin A24 + Succinate + CO2 + H2O
Gibberellin A14 <=> Gibberellin A37 open lactone
Gibberellin A37 open lactone <=> Gibberellin A36
Gibberellin A24 <=> Gibberellin A9 + CO2
Gibberellin A36 <=> Gibberellin A4 + CO2
Gibberellin A12 aldehyde <=> Gibberellin A53 aldehyde
Gibberellin A12 <=> Gibberellin A53
Gibberellin A15 open lactone <=> Gibberellin A44 diacid
Gibberellin A24 <=> Gibberellin A19
Gibberellin A9 <=> Gibberellin A20
Gibberellin A12 <=> Gibberellin A14
Gibberellin A15 open lactone <=> Gibberellin A37 open lactone
Gibberellin A24 + 2-Oxoglutarate + Oxygen <=> Gibberellin A36 + Succinate + CO2
Gibberellin A9 + 2-Oxoglutarate + Oxygen <=> Gibberellin A4 + Succinate + CO2
Gibberellin A9 + 2-Oxoglutarate + Oxygen <=> Gibberellin A51 + Succinate + CO2
Gibberellin A4 + 2-Oxoglutarate + Oxygen <=> Gibberellin A34 + Succinate + CO2
Gibberellin A14 aldehyde <=> Gibberellin A14
Gibberellin A53 aldehyde <=> Gibberellin A53
Gibberellin A12 aldehyde <=> Gibberellin A14 aldehyde
Gibberellin A34 <=> Gibberellin A34-catabolite
Gibberellin A51 <=> Gibberellin A51-catabolite
Gibberellin A29 <=> Gibberellin A29-catabolite
Gibberellin A8 <=> Gibberellin A8-catabolite
Gibberellin A20 <=> Gibberellin A5
Gibberellin A5 <=> Gibberellin A3
Gibberellin A5 <=> Gibberellin A6
Gibberellin A9 <=> 2,3-Dehydro-gibberellin A9
2,3-Dehydro-gibberellin A9 <=> Gibberellin A7
(-)-Abietadiene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abietinol + [Oxidized NADPH---hemoprotein reductase] + H2O
Levopimaradiene <=> Levopimarinol
Neoabietadiene <=> Neoabietinol
Abietinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abietal + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Levopimarinol <=> Levopimarinal
Neoabietinol <=> Neoabietal
Abietal + H2O + NAD+ <=> Abietate + NADH + 2 H+
Levopimarinal <=> Levopimaric acid
Neoabietal <=> Neoabietic acid
Isopenicillin N + Acyl-CoA + H2O <=> Penicillin + CoA + L-2-Aminoadipate
Penicillin + H2O <=> Penicilloic acid
CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine
O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate + NDP-N-methyl-L-glucosamine <=> Dihydrostreptomycin 6-phosphate + NDP
Perillyl aldehyde + H2O + NAD+ <=> Perillic acid + NADH + H+
Perillic acid + CoA + ATP <=> Perillyl-CoA + H2O + ADP + Orthophosphate
Perillic acid + CoA + ATP <=> Perillyl-CoA + H2O + AMP + Diphosphate
Perillyl-CoA + H2O <=> 2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA
2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA + Acceptor <=> 4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA + Reduced acceptor
4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA + H2O <=> 3-Isopropenylpimelyl-CoA
(+)-(S)-Carvone + Reduced acceptor <=> (1R,4S)-Iso-dihydrocarvone + Acceptor
(-)-Carvone + Reduced acceptor <=> (1R,4R)-Dihydrocarvone + Acceptor
(4R,6R)-cis-Carveol <=> (-)-Carvone
(4S,6S)-cis-Carveol <=> (+)-(S)-Carvone
(1R,2R,4R)-Dihydrocarveol + NAD+ <=> (1R,4R)-Dihydrocarvone + NADH + H+
(1R,2R,4S)-Iso-dihydrocarveol + NAD+ <=> (1R,4S)-Iso-dihydrocarvone + NADH + H+
(1R,2S,4R)-Neo-dihydrocarveol + NAD+ <=> (1R,4R)-Dihydrocarvone + NADH + H+
(1R,2S,4S)-Neoiso-dihydrocarveol + NAD+ <=> (1R,4S)-Iso-dihydrocarvone + NADH + H+
(1R,4R)-Dihydrocarvone <=> (1S,4R)-Iso-dihydrocarvone
(1R,4S)-Iso-dihydrocarvone <=> (1S,4S)-Dihydrocarvone
(1S,2S,4R)-Iso-dihydrocarveol + NAD+ <=> (1S,4R)-Iso-dihydrocarvone + NADH + H+
(1S,2S,4S)-Dihydrocarveol + NAD+ <=> (1S,4S)-Dihydrocarvone + NADH + H+
(1S,2R,4R)-Neoiso-dihydrocarveol + NAD+ <=> (1S,4R)-Iso-dihydrocarvone + NADH + H+
(1S,2R,4S)-Neo-dihydrocarveol + NAD+ <=> (1S,4S)-Dihydrocarvone + NADH + H+
(1R,4R)-Dihydrocarvone + NADPH + Oxygen + H+ <=> (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O
(1R,4S)-Iso-dihydrocarvone + NADPH + Oxygen + H+ <=> (4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O
(1S,4R)-Iso-dihydrocarvone + NADPH + Oxygen + H+ <=> (3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + NADP+ + H2O
(1S,4S)-Dihydrocarvone + NADPH + Oxygen + H+ <=> (3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + NADP+ + H2O
(4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + H2O <=> (3R)-6-Hydroxy-3-isopropenyl-heptanoate
(3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O <=> (5R)-6-Hydroxy-5-isopropenyl-2-methylhexanoate
(4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + H2O <=> (3S)-6-Hydroxy-3-isopropenyl-heptanoate
(3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O <=> (5S)-6-Hydroxy-5-isopropenyl-2-methylhexanoate
(3R)-6-Hydroxy-3-isopropenyl-heptanoate <=> (3R)-3-Isopropenyl-6-oxoheptanoate
(3S)-6-Hydroxy-3-isopropenyl-heptanoate <=> (3S)-3-Isopropenyl-6-oxoheptanoate
(3R)-3-Isopropenyl-6-oxoheptanoate + CoA + ATP <=> (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA + H2O + ADP + Orthophosphate
(3S)-3-Isopropenyl-6-oxoheptanoate <=> (3S)-3-Isopropenyl-6-oxoheptanoyl-CoA
(R)-Limonene + NADH + Oxygen + H+ <=> Limonene-1,2-epoxide + NAD+ + H2O
Limonene-1,2-diol + NAD+ <=> (1S,4R)-1-Hydroxy-2-oxolimonene + NADH + H+
(1S,4R)-1-Hydroxy-2-oxolimonene + NADPH + Oxygen + H+ <=> (4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O
alpha-Pinene + Reduced acceptor + Oxygen <=> Myrtenol + H2O + Acceptor
Myrtenol + Oxygen + Acceptor <=> Myrtenal + 2 H2O + Reduced acceptor
Myrtenal + H2O + Acceptor <=> Myrtenic acid + Reduced acceptor
alpha-Pinene + Oxygen + 2 H+ + 2 e- <=> Pinocarveol + H2O
Pinocarveol <=> Pinocarvone + H+
alpha-Pinene + NADH + H+ + Oxygen <=> alpha-Pinene-oxide + NAD+ + H2O
(Z)-2-Methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O <=> cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid + NADH + H+
trans-2-Methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O <=> trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid + NADH + H+
cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoA <=> cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + Diphosphate
trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoA <=> trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + Diphosphate
cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + H2O <=> 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA
trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + H2O <=> 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA
3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ <=> 2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH + H+
2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoA <=> 3-Isopropylbut-3-enoyl-CoA + Propanoyl-CoA
3-Isopropylbut-3-enoyl-CoA + H2O <=> 3-Isopropyl-3-butenoic acid + CoA
(-)-Isopiperitenone + NADPH + H+ <=> (+)-cis-Isopulegone + NADP+
(+)-cis-Isopulegone <=> Pulegone
Pulegone + NADPH + H+ <=> (-)-Menthone + NADP+
Pulegone + NADPH + H+ <=> (+)-Isomenthone + NADP+
Geranyl diphosphate + H2O <=> (-)-alpha-Terpineol + Diphosphate
(-)-alpha-Terpineol <=> 1,8-Cineole
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate <=> dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate
dTDP-4-oxo-6-deoxy-D-glucose <=> 3,6-Dideoxy-3-oxo-dTDP-D-glucose
dTDP-3-oxo-4,6-dideoxy-D-glucose + L-Glutamate <=> dTDP-3-amino-3,4,6-trideoxy-D-glucose + 2-Oxoglutarate
dTDP-3-amino-3,4,6-trideoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-desosamine + 2 S-Adenosyl-L-homocysteine
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H2O
dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+ <=> dTDP-L-olivose + NADP+
dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose + NADPH + H+ <=> dTDP-L-mycarose + NADP+
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-4-oxo-6-deoxy-D-allose
dTDP-6-deoxy-D-allose + NAD+ <=> dTDP-4-oxo-6-deoxy-D-allose + NADH + H+
dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose <=> Maltol + dTDP
dTDP-4-dehydro-beta-L-rhamnose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
dTDP-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-D-olivose
trans,trans-Farnesyl diphosphate + 8 Isopentenyl diphosphate <=> di-trans,poly-cis-Undecaprenyl diphosphate + 8 Diphosphate
5 Methylmalonyl-CoA + 2 Malonyl-CoA + (2S)-Ethylmalonyl-CoA + 7 NADPH + 7 H+ <=> 8 CoA + Tylactone + 8 CO2 + 3 H2O + 7 NADP+
5-O-beta-D-Mycaminosyltylactone + 2 NADPH + 2 Oxygen + 2 H+ <=> 20-Oxo-5-O-beta-mycaminosyltylactone + 2 NADP+ + 3 H2O
Tylactone + dTDP-D-mycaminose <=> 5-O-beta-D-Mycaminosyltylactone + dTDP
5-O-beta-D-Mycaminosyltylonolide + dTDP-6-deoxy-D-allose <=> Demethyllactenocin + dTDP
Demethyllactenocin + dTDP-L-mycarose <=> Demethylmacrocin + dTDP
Malonyl-CoA + 6 Methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 8,8a-Deoxyoleandolide + 7 CoA + 7 CO2 + H2O + 6 NADP+
8,8a-Deoxyoleandolide + 2 NADPH + 2 H+ + 2 Oxygen <=> Oleandolide + 2 NADP+ + 3 H2O
Oleandolide + dTDP-L-olivose <=> L-Olivosyl-oleandolide + dTDP
L-Olivosyl-oleandolide + S-Adenosyl-L-methionine <=> L-Oleandrosyl-oleandolide + S-Adenosyl-L-homocysteine
L-Oleandrosyl-oleandolide + dTDP-D-desosamine <=> Oleandomycin + dTDP
5 (S)-Methylmalonyl-CoA + Malonyl-CoA + 5 NADPH + 5 H+ <=> 10-Deoxymethynolide + 6 CoA + 6 CO2 + 5 NADP+ + 2 H2O
6 (S)-Methylmalonyl-CoA + Malonyl-CoA + 5 NADPH + 5 H+ <=> Narbonolide + 7 CoA + 7 CO2 + 5 NADP+ + 2 H2O
10-Deoxymethynolide + dTDP-D-desosamine <=> 10-Deoxymethymycin + dTDP
Narbonolide + dTDP-D-desosamine <=> Narbomycin + dTDP
10-Deoxymethymycin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Neomethymycin + 2 Oxidized ferredoxin + H2O
10-Deoxymethymycin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Methymycin + 2 Oxidized ferredoxin + H2O
Narbomycin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Pikromycin + 2 Oxidized ferredoxin + H2O
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2a'' aglycone + NADP+ + H2O
(S)-2,3-Epoxysqualene <=> Lupeol
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''1a'' aglycone + NADP+ + H2O
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2b'' aglycone + NADP+ + H2O
(S)-2,3-Epoxysqualene <=> beta-Amyrin
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''1b'' aglycone + NADP+ + H2O
(S)-2,3-Epoxysqualene <=> alpha-Amyrin
5-Oxoavermectin ''2a'' aglycone + NADPH + H+ <=> Avermectin B2a aglycone + NADP+
5-Oxoavermectin ''1a'' aglycone + NADPH + H+ <=> Avermectin B1a aglycone + NADP+
5-Oxoavermectin ''2b'' aglycone + NADPH + H+ <=> Avermectin B2b aglycone + NADP+
5-Oxoavermectin ''1b'' aglycone + NADPH + H+ <=> Avermectin B1b aglycone + NADP+
Avermectin B2a aglycone + S-Adenosyl-L-methionine <=> Avermectin A2a aglycone + S-Adenosyl-L-homocysteine
Avermectin B1a aglycone + S-Adenosyl-L-methionine <=> Avermectin A1a aglycone + S-Adenosyl-L-homocysteine
Avermectin B2b aglycone + S-Adenosyl-L-methionine <=> Avermectin A2b aglycone + S-Adenosyl-L-homocysteine
Avermectin B1b aglycone + S-Adenosyl-L-methionine <=> Avermectin A1b aglycone + S-Adenosyl-L-homocysteine
2-Methylbutanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+
2-Methylbutanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1a'' aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+
2-Methylpropanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+
2-Methylpropanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1b'' aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+
Avermectin B2a aglycone + dTDP-L-oleandrose <=> Avermectin B2a monosaccharide + dTDP
Avermectin B2a monosaccharide + dTDP-L-oleandrose <=> Avermectin B2a + dTDP
Avermectin A2a aglycone + dTDP-L-oleandrose <=> Avermectin A2a monosaccharide + dTDP
Avermectin A2a monosaccharide + dTDP-L-oleandrose <=> Avermectin A2a + dTDP
Avermectin B1a aglycone + dTDP-L-oleandrose <=> Avermectin B1a monosaccharide + dTDP
Avermectin B1a monosaccharide + dTDP-L-oleandrose <=> Avermectin B1a + dTDP
Avermectin A1a aglycone + dTDP-L-oleandrose <=> Avermectin A1a monosaccharide + dTDP
Avermectin A1a monosaccharide + dTDP-L-oleandrose <=> Avermectin A1a + dTDP
Avermectin B2b aglycone + dTDP-L-oleandrose <=> Avermectin B2b monosaccharide + dTDP
Avermectin B2b monosaccharide + dTDP-L-oleandrose <=> Avermectin B2b + dTDP
Avermectin A2b aglycone + dTDP-L-oleandrose <=> Avermectin A2b monosaccharide + dTDP
Avermectin A2b monosaccharide + dTDP-L-oleandrose <=> Avermectin A2b + dTDP
Avermectin B1b aglycone + dTDP-L-oleandrose <=> Avermectin B1b monosaccharide + dTDP
Avermectin B1b monosaccharide + dTDP-L-oleandrose <=> Avermectin B1b + dTDP
Avermectin A1b aglycone + dTDP-L-oleandrose <=> Avermectin A1b monosaccharide + dTDP
Avermectin A1b monosaccharide + dTDP-L-oleandrose <=> Avermectin A1b + dTDP
Soyasapogenol B <=> Soyasaponin I
beta-Amyrin + Oxygen <=> Soyasapogenol B
(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid <=> (5Z,7E,9E,14Z,17Z)-Icosapentaenoate
Megalomicin A <=> Megalomicin B
Megalomicin A <=> Megalomicin C1
Megalomicin A <=> Megalomicin C2
Erythromycin C + dTDP-L-megosamine <=> Megalomicin A + dTDP
Acetyl-CoA + 2 Malonyl-CoA <=> Triacetate lactone + 3 CoA + 2 CO2
dTDP-glucose <=> dTDP-4-oxo-6-deoxy-D-glucose + H2O
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-4-dehydro-beta-L-rhamnose
(3R)-3-Isopropenyl-6-oxoheptanoate + CoA + ATP <=> (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA + H2O + AMP + Diphosphate
Sphingosine 1-phosphate <=> Ethanolamine phosphate + Hexadecenal
Acyl-CoA + Sphinganine <=> CoA + Dihydroceramide
Dihydroceramide + H2O <=> Fatty acid + Sphinganine
Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> N-Acylsphingosine + 2 Ferricytochrome b5 + 2 H2O
Sphinganine 1-phosphate + H2O <=> Sphinganine + Orthophosphate
Sphingosine 1-phosphate + H2O <=> Sphingosine + Orthophosphate
Ceramide 1-phosphate + H2O <=> N-Acylsphingosine + Orthophosphate
trans,trans-Farnesyl diphosphate <=> Vetispiradiene + Diphosphate
Sphinganine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Phytosphingosine + 2 Ferricytochrome b5 + H2O
Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Phytoceramide + 2 Ferricytochrome b5 + H2O
C26-CoA + Phytosphingosine <=> CoA + Phytoceramide
Phytoceramide + H2O <=> Fatty acid + Phytosphingosine
Adenosyl cobyrinate hexaamide + D-1-Aminopropan-2-ol O-phosphate + ATP <=> Adenosyl cobinamide phosphate + ADP + Orthophosphate
L-Threonine O-3-phosphate <=> D-1-Aminopropan-2-ol O-phosphate + CO2
L-Threonine + ATP <=> L-Threonine O-3-phosphate + ADP
Leucocyanidin + NADPH + H+ <=> (+)-Catechin + NADP+ + H2O
Leucodelphinidin + NADPH + H+ <=> (+)-Gallocatechin + NADP+ + H2O
Pelargonidin + UDP-glucose <=> Pelargonidin 3-O-glucoside + UDP
Cyanidin + UDP-glucose <=> Chrysanthemin + UDP
Delphinidin + UDP-glucose <=> Delphinidin 3-O-glucoside + UDP
Apigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Luteolin + [Oxidized NADPH---hemoprotein reductase] + H2O
Kaempferol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Quercetin + [Oxidized NADPH---hemoprotein reductase] + H2O
Dihydromyricetin + 2-Oxoglutarate + Oxygen <=> Myricetin + Succinate + CO2 + H2O
cis-3,4-Leucopelargonidin + 2-Oxoglutarate + Oxygen <=> Dihydrokaempferol + Succinate + CO2 + H2O
(-)-Epiafzelechin + 2 NADP+ <=> Pelargonidin + 2 NADPH + H+
(-)-Epicatechin + 2 NADP+ <=> Cyanidin + 2 NADPH + H+
(-)-Epigallocatechin + 2 NADP+ <=> Delphinidin + 2 NADPH + H+
Chrysanthemin + p-Coumaroyl-CoA <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside + CoA
Cyanin + p-Coumaroyl-CoA <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + CoA
Chrysanthemin + UDP-glucose <=> Cyanin + UDP
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside + UDP-glucose <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + UDP
Chrysanthemin <=> Peonidin 3-O-glucoside
Delphinidin 3-O-glucoside <=> Petunidin 3-O-glucoside
Delphinidin 3-O-glucoside <=> Malvidin 3-O-glucoside
Pentahydroxyflavanone + 2-Oxoglutarate + Oxygen <=> Tricetin + Succinate + CO2 + H2O
Naringenin <=> Genistein
Liquiritigenin <=> Daidzein
Isoliquiritigenin <=> Liquiritigenin
Adenosyl cobinamide + GTP <=> Adenosyl cobinamide phosphate + GDP
Formononetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxyformononetin + [Oxidized NADPH---hemoprotein reductase] + H2O
Biochanin A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxybiochanin A + [Oxidized NADPH---hemoprotein reductase] + H2O
2'-Hydroxyformononetin + NADPH + H+ <=> (-)-Vestitone + NADP+
2'-Hydroxybiochanin A + NADPH + H+ <=> Ferreirin + NADP+
Daidzein + S-Adenosyl-L-methionine <=> Formononetin + S-Adenosyl-L-homocysteine
(-)-Vestitone <=> Medicarpin
p-Coumaroyl-CoA + 3 Malonyl-CoA + NADPH + H+ <=> Isoliquiritigenin + 4 CoA + 3 CO2 + NADP+ + H2O
5-Hydroxyferuloyl-CoA + NADPH + H+ <=> 5-Hydroxyconiferaldehyde + CoA + NADP+
5-Hydroxyconiferaldehyde + NADPH + H+ <=> 5-Hydroxyconiferyl alcohol + NADP+
Caffeic aldehyde + NADPH + H+ <=> Caffeyl alcohol + NADP+
Coniferyl aldehyde + NADPH + H+ + Oxygen <=> 5-Hydroxyconiferaldehyde + NADP+ + H2O
Coniferyl alcohol + NADPH + H+ + Oxygen <=> 5-Hydroxyconiferyl alcohol + NADP+ + H2O
Caffeic aldehyde + S-Adenosyl-L-methionine <=> Coniferyl aldehyde + S-Adenosyl-L-homocysteine
Caffeyl alcohol + S-Adenosyl-L-methionine <=> Coniferyl alcohol + S-Adenosyl-L-homocysteine
5-Hydroxyconiferaldehyde + S-Adenosyl-L-methionine <=> Sinapoyl aldehyde + S-Adenosyl-L-homocysteine
5-Hydroxyconiferyl alcohol + S-Adenosyl-L-methionine <=> Sinapyl alcohol + S-Adenosyl-L-homocysteine
5-Hydroxyferuloyl-CoA + S-Adenosyl-L-methionine <=> Sinapoyl-CoA + S-Adenosyl-L-homocysteine
4-Hydroxycinnamyl aldehyde <=> Caffeic aldehyde
4-Coumaryl alcohol <=> Caffeyl alcohol
4-Coumaroylshikimate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-O-Caffeoylshikimic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
5-Hydroxyferulic acid methyl ester + CoA + ATP <=> 5-Hydroxyferuloyl-CoA + AMP + Diphosphate
Feruloyl-CoA <=> 5-Hydroxyferuloyl-CoA
UDP-3-ketoglucose + L-Glutamate <=> UDP-kanosamine + 2-Oxoglutarate
UDP-kanosamine <=> Kanosamine
ATP + Kanosamine <=> ADP + Kanosamine 6-phosphate
Kanosamine 6-phosphate <=> Aminofructose 6-phosphate
Aminofructose 6-phosphate + D-Ribose 5-phosphate <=> Iminoerythrose 4-phosphate + Sedoheptulose 7-phosphate
Iminoerythrose 4-phosphate + Phosphoenolpyruvate + H2O <=> AminoDAHP + Orthophosphate
AminoDAHP <=> AminoDHQ + Orthophosphate
AminoDHQ <=> 5-Amino-5-deoxy-3-dehydroshikimate + H2O
UDP-glucose + NAD+ <=> UDP-3-ketoglucose + NADH + H+
5-Amino-5-deoxy-3-dehydroshikimate <=> 3-Amino-5-hydroxybenzoate + H2O
Proansamycin X <=> Protorifamycin I
Protorifamycin I <=> Rifamycin W
Proansamycin X <=> 34a-Deoxy-rifamycin W
Rifamycin <=> Rifamycin B
5-Hydroxyisourate + H2O <=> 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
Isochorismate <=> Salicylate + Pyruvate
Chorismate <=> Salicylate + Pyruvate
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate <=> (S)-Allantoin + CO2
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+ <=> (R)(-)-Allantoin + CO2
Daidzein + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxydaidzein + [Oxidized NADPH---hemoprotein reductase] + H2O
Genistein + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxygenistein + [Oxidized NADPH---hemoprotein reductase] + H2O
Naringenin + NADPH + H+ <=> Apiforol + NADP+
Kaempferol + UDP-glucose <=> Kaempferol 3-O-glucoside + UDP
5,6-Indolequinone-2-carboxylic acid <=> Eumelanin
5,10-Methylenetetrahydrofolate + dUMP + NADPH + H+ <=> Tetrahydrofolate + dTMP + NADP+
3-Cyano-L-alanine <=> 3-Aminopropiononitrile + CO2
cis-3,4-Leucopelargonidin + NADPH + H+ <=> Afzelechin + NADP+ + H2O
Gibberellin A4 <=> Gibberellin A7
Gibberellin A7 <=> Gibberellin A3
Gibberellin A4 <=> Gibberellin A1
D-Glucose + Ubiquinone <=> D-Glucono-1,5-lactone + Ubiquinol
cis-1,2-Cyclohexanediol + NAD+ <=> 2-Hydroxycyclohexan-1-one + NADH
NADPH + 2-Hydroxycyclohexan-1-one + H+ + Oxygen <=> NADP+ + 1-Oxa-2-oxo-3-hydroxycycloheptane + H2O
G00144 + H2O <=> 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate
3,5-Dihydroxyphenylacetyl-CoA + Oxygen <=> 3,5-Dihydroxyphenylglyoxylate + CoA
4 Malonyl-CoA <=> 3,5-Dihydroxyphenylacetyl-CoA + 3 CoA + 4 CO2 + H2O
4-Hydroxyphenylglyoxylate + L-Tyrosine <=> L-4-Hydroxyphenylglycine + 3-(4-Hydroxyphenyl)pyruvate
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + S-Adenosyl-L-methionine <=> dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose + S-Adenosyl-L-homocysteine
dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose <=> dTDP-L-4-oxovancosamine
dTDP-L-4-oxovancosamine + NADPH + H+ <=> dTDP-L-epivancosamine + NADP+
dTDP-L-4-oxovancosamine <=> dTDP-L-vancosamine
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + L-Glutamate <=> dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + 2-Oxoglutarate
3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> (S)-4-Hydroxymandelate + CO2
(S)-4-Hydroxymandelate + Oxygen <=> 4-Hydroxyphenylglyoxylate + Hydrogen peroxide
3,5-Dihydroxy-phenylglycine + 2-Oxoglutarate <=> 3,5-Dihydroxyphenylglyoxylate + L-Glutamate
Acetyl-CoA + 7 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 7 CO2 + 7 CoA
Butanoyl-CoA + 7 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-octadecanoyl-[acp] + 7 CO2 + 7 CoA
Malonamoyl-CoA + 8 Malonyl-CoA + Acyl-carrier protein <=> 18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + 8 CO2 + 9 CoA
18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + NADPH + H+ <=> C-9 Reduced nonaketamide + NADP+
10 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] + 10 CO2 + 10 CoA
Propanoyl-CoA + 9 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-henicosanoyl-[acp] + 9 CO2 + 9 CoA
Butanoyl-CoA + 9 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-docosanoyl-[acp] + 9 CO2 + 9 CoA
Tetrangomycin <=> Tetrangulol + H2O
Tetrangulol <=> 8-O-Methyltetrangulol
8-O-Methyltetrangulol <=> 19-Hydroxy-8-O-methyltetrangulol
Tetrangulol <=> 19-Hydroxytetrangulol
19-Hydroxytetrangulol <=> 19-Hydroxy-8-O-methyltetrangulol
19-Hydroxy-8-O-methyltetrangulol <=> PD116740
Tetrangomycin <=> Rabelomycin
Urdamycinone B + dTDP-beta-L-rhodinose <=> 100-1 + dTDP
100-1 + dTDP-D-olivose <=> Urdamycin B + dTDP
Urdamycinone B <=> 104-2
104-2 + dTDP-beta-L-rhodinose + dTDP-D-olivose <=> 124-1 + 2 dTDP
Urdamycinone F + 2 dTDP-beta-L-rhodinose + dTDP-D-olivose <=> Urdamycin F + 3 dTDP
Urdamycinone F <=> Aquayamycin + H2O
Aquayamycin + dTDP-beta-L-rhodinose <=> 100-2 + dTDP
100-2 + dTDP-beta-L-rhodinose <=> Urdamycin G + dTDP
Urdamycin G + dTDP-D-olivose <=> Urdamycin A + dTDP
Jadomycin A <=> Jadomycin B
Dehydrorabelomycin <=> Kinobscurinone
Kinobscurinone <=> Stealthin C
Stealthin C <=> Prekinamycin
Prekinamycin <=> Kinamycin D
Nogalonate + S-Adenosyl-L-methionine <=> Methyl nogalonate + S-Adenosyl-L-homocysteine
Methyl nogalonate <=> Auraviketone
Auraviketone + NADPH + H+ <=> Auramycinone + NADP+
Methyl nogalonate <=> Dihydro-NAME
12-Deoxyaklanonic acid + Oxygen <=> Aklanonate + H2O
Aklanonate + S-Adenosyl-L-methionine <=> Methyl aklanonate + S-Adenosyl-L-homocysteine
Methyl aklanonate <=> Aklaviketone
Aklaviketone + NADPH + H+ <=> Aklavinone + NADP+
Aklavinone + NADPH + H+ + Oxygen <=> epsilon-Rhodomycinone + NADP+ + H2O
epsilon-Rhodomycinone + dTDP-beta-L-daunosamine <=> Rhodomycin D + dTDP
Rhodomycin D + H2O <=> 10-Carboxy-13-deoxycarminomycin + Methanol
10-Carboxy-13-deoxycarminomycin <=> 13-Deoxycarminomycin + CO2
13-Deoxycarminomycin + S-Adenosyl-L-methionine <=> 13-Deoxydaunorubicin + S-Adenosyl-L-homocysteine
13-Deoxydaunorubicin + NADPH + H+ + Oxygen <=> 13-Dihydrodaunorubicin + NADP+ + H2O
13-Dihydrodaunorubicin + NADPH + H+ + Oxygen <=> Daunorubicin + NADP+ + 2 H2O
Daunorubicin + NADPH + H+ + Oxygen <=> Doxorubicin + NADP+ + H2O
13-Deoxycarminomycin + NADPH + H+ + Oxygen <=> 13-Dihydrocarminomycin + NADP+ + H2O
13-Dihydrocarminomycin + NADPH + H+ + Oxygen <=> Carminomycin + NADP+ + 2 H2O
Carminomycin + S-Adenosyl-L-methionine <=> Daunorubicin + S-Adenosyl-L-homocysteine
Daunorubicin <=> (13S)-13-Dihydrodaunorubicin
(S)-DNPA <=> 6-Deoxydihydrokalafungin
6-Deoxydihydrokalafungin + Oxygen <=> Dihydrokalafungin + H2O
2 DHKred-OH <=> Actinorhodin
Dihydrokalafungin <=> Medermycin
Tetracenomycin F2 <=> Tetracenomycin F1 + H2O
Tetracenomycin F1 + Oxygen <=> Tetracenomycin D3 + H2O
Tetracenomycin D3 <=> Tetracenomycin B3
Tetracenomycin B3 <=> Tetracenomycin E
Tetracenomycin E + S-Adenosyl-L-methionine <=> Tetracenomycin A2 + S-Adenosyl-L-homocysteine
Tetracenomycin A2 + 2 Oxygen + H2O + 2 NADPH + 2 H+ <=> Tetracenomycin C + 2 NADP+ + 2 H2O
Tetracenomycin F1 <=> Tetracenomycin F1 methylester
Tetracenomycin F1 <=> Decarboxytetracenomycin F1
Tetracenomycin D3 <=> Tetracenomycin D3 methylester
Tetracenomycin D3 <=> Tetracenomycin D1
Tetracenomycin B3 <=> Tetracenomycin B1
S-Adenosyl-L-methionine + Tetracenomycin B3 <=> S-Adenosyl-L-homocysteine + Tetracenomycin B2
Tetracenomycin A2 <=> Tetracenomycin X
4-Demethylpremithramycinone + S-Adenosyl-L-methionine <=> Premithramycinone + S-Adenosyl-L-homocysteine
Premithramycinone + dTDP-D-olivose <=> Premithramycin A1 + dTDP
Premithramycin A1 + dTDP-D-oliose <=> Premithramycin A2' + dTDP
Premithramycin A2' + dTDP-D-mycarose <=> Premithramycin A3' + dTDP
Premithramycin A3' + S-Adenosyl-L-methionine <=> Premithramycin A3 + S-Adenosyl-L-homocysteine
H2O + G00011 <=> D-Mannose + G10694
sym-Homospermidine <=> Trachelanthamidine
Trachelanthamidine <=> Retronecine
Retronecine + 2 L-Isoleucine <=> Senecionine
1-Methylpyrrolinium + Benzoate <=> Cocaine
Cocaine + H2O <=> Ecgonine methyl ester + Benzoate
Ecgonine methyl ester + H2O <=> Ecgonine + Methanol
Ecgonine <=> Pseudoecgonine
Pseudoecgonine + ATP + CoA <=> Pseudoecgonyl-CoA + AMP
1-Methylpyrrolinium <=> Hygrine
Hygrine <=> Tropinone
Tropinone + NADPH + H+ <=> Pseudotropine + NADP+
Acetyl-CoA + Tropine <=> CoA + Acetyltropine
Acetyl-CoA + Pseudotropine <=> CoA + Acetylpseudotropine
Pseudotropine <=> Calystegin A3
Nicotine <=> Nornicotine
Cadaverine + H2O + Oxygen <=> 5-Aminopentanal + Ammonia + Hydrogen peroxide
5-Aminopentanal <=> Piperideine
Anabasine <=> Anatalline
L-Phenylalanine <=> Tropate
trans-Cinnamate <=> Cocaine
L-Proline + Peptidyl-carrier protein + ATP <=> L-Prolyl-[pcp] + AMP + Diphosphate
L-Prolyl-[pcp] + 2 Electron-transferring flavoprotein <=> Pyrrole-2-carbonyl-[pcp] + 2 Reduced electron-transferring flavoprotein
Pyrrole-2-carbonyl-[pcp] + Peptidyl-carrier protein <=> Pyrrole-2-carbonyl-[pcp] + Peptidyl-carrier protein
L-Tyrosine + Peptidyl-carrier protein + ATP <=> L-Tyrosyl-[pcp] + AMP + Diphosphate
L-Tyrosyl-[pcp] + Oxygen <=> beta-Hydroxy-L-tyrosyl-[pcp] + H2O
beta-Hydroxy-L-tyrosyl-[pcp] <=> beta-Keto-L-tyrosyl-[pcp]
3-(4-Hydroxyphenyl)pyruvate + Dimethylallyl diphosphate <=> 3-Dimethylallyl-4-hydroxyphenylpyruvate + Diphosphate
3-Dimethylallyl-4-hydroxyphenylpyruvate + Oxygen <=> 3-Dimethylallyl-4-hydroxymandelic acid + CO2
3-Dimethylallyl-4-hydroxymandelic acid + Oxygen <=> 3-Dimethylallyl-4-hydroxybenzoate + CO2 + H2O
beta-Hydroxy-L-tyrosyl-[pcp] <=> 3-Dimethylallyl-beta-hydroxy-L-tyrosyl-[pcp]
3-Dimethylallyl-beta-hydroxy-L-tyrosyl-[pcp] <=> 3-Dimethylallyl-4-hydroxybenzaldehyde
3-Dimethylallyl-4-hydroxyphenylpyruvate <=> 3-Dimethylallyl-4-hydroxybenzaldehyde
3-Dimethylallyl-4-hydroxybenzaldehyde <=> 3-Dimethylallyl-4-hydroxybenzoate
beta-Keto-L-tyrosyl-[pcp] <=> 2-Hydroxy-beta-keto-L-tyrosyl-[pcp]
2-Hydroxy-beta-keto-L-tyrosyl-[pcp] <=> 3-Amino-4,7-dihydroxycoumarin
3-Amino-4,7-dihydroxycoumarin <=> 3-Amino-4,7-dihydroxy-8-chlorocoumarin
Coumermic acid + 2 dTDP-5-dimethyl-L-lyxose + 2 S-Adenosyl-L-methionine <=> Coumermycin D + 2 dTDP + 2 S-Adenosyl-L-homocysteine
Coumermycin D + 2 Pyrrole-2-carbonyl-[pcp] <=> Coumermycin A1
Novobiocic acid + dTDP-5-dimethyl-L-lyxose <=> Demethyldecarbamoylnovobiocin + dTDP
Demethyldecarbamoylnovobiocin + S-Adenosyl-L-methionine <=> Decarbamoylnovobiocin + S-Adenosyl-L-homocysteine
Decarbamoylnovobiocin + Carbamoyl phosphate <=> Novobiocin + Orthophosphate
Chlorobiocic acid + dTDP-5-dimethyl-L-lyxose <=> Novclobiocin 105 + dTDP
Novclobiocin 105 + S-Adenosyl-L-methionine <=> Novclobiocin 104 + S-Adenosyl-L-homocysteine
Novclobiocin 104 + Pyrrole-2-carbonyl-[pcp] <=> Clorobiocin
3-Amino-4,7-dihydroxy-8-chlorocoumarin + 3-Dimethylallyl-4-hydroxybenzoate <=> Chlorobiocic acid
3-Methylpyrrole-2,4-dicarboxylic acid + 3-Amino-4,7-dihydroxycoumarin + ATP <=> 5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + AMP + Diphosphate
5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + 3-Amino-4,7-dihydroxycoumarin + ATP + 2 S-Adenosyl-L-methionine <=> Coumermic acid + AMP + Diphosphate + 2 S-Adenosyl-L-homocysteine
Nicotinate + 3,6-Dihydropyridine <=> Anatabine + CO2
Phenylpropanoate <=> 3-(3-Hydroxyphenyl)propanoic acid
trans-Cinnamate <=> trans-3-Hydroxycinnamate
Phenylpropanoate + Oxygen + NADH + H+ <=> cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol + NAD+
trans-Cinnamate + Oxygen + NADH + H+ <=> cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+
cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol + NAD+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + NADH + H+
cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+ <=> trans-2,3-Dihydroxycinnamate + NADH + H+
3-(3-Hydroxyphenyl)propanoic acid + Oxygen + NADH + H+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + H2O + NAD+
trans-3-Hydroxycinnamate + Oxygen + NADH + H+ <=> trans-2,3-Dihydroxycinnamate + H2O + NAD+
trans-2,3-Dihydroxycinnamate + Oxygen <=> 2-Hydroxy-6-ketononatrienedioate
2-Hydroxy-6-ketononatrienedioate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Fumarate
Phenylacetic acid <=> 4-Hydroxyphenylacetate
Phenylacetic acid <=> 3-Hydroxyphenylacetate
Apigenin + 2 NADPH + 2 H+ + Oxygen <=> 2-Hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O
2-Hydroxy-2,3-dihydrogenistein <=> Genistein + H2O
Genistein + S-Adenosyl-L-methionine <=> Prunetin + S-Adenosyl-L-homocysteine
Biochanin A + UDP-glucose <=> Biochanin A-beta-D-glucoside + UDP
Biochanin A-beta-D-glucoside + Malonyl-CoA <=> Biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) + CoA
Quercetin 3-O-glucoside + Malonyl-CoA <=> Quercetin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-glucoside <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + Malonyl-CoA <=> 4'''-Demalonylsalvianin + CoA
4'''-Demalonylsalvianin + Malonyl-CoA <=> Salvianin + CoA
Pelargonidin 3-O-glucoside + Malonyl-CoA <=> Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-glucoside + UDP-L-rhamnose <=> Pelargonidin 3-O-rutinoside + UDP
Pelargonidin 3-O-rutinoside + UDP-glucose <=> Pelargonidin 3-O-rutinoside 5-O-beta-D-glucoside + UDP
Kaempferol 3-O-glucoside + UDP-glucose <=> Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP
Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-glucose <=> Kaempferol 3-sophorotrioside + UDP
Kaempferol 3-sophorotrioside + p-Coumaroyl-CoA <=> Kaempferol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] + CoA
Kaempferol + S-Adenosyl-L-methionine <=> Kaempferide + S-Adenosyl-L-homocysteine
Kaempferol + UDP-alpha-D-galactose <=> Kaempferol-3-O-galactoside + UDP
Quercetin 3,4'-bissulfate + 3'-Phosphoadenylyl sulfate <=> Quercetin 3,4',7-trissulfate + Adenosine 3',5'-bisphosphate
Quercetin + UDP-glucose <=> Quercimeritrin + UDP
Rutin + UDP-D-xylose <=> Quercetin 3-(2G-xylosylrutinoside) + UDP
Quercetin 3-O-glucoside + UDP-glucose <=> Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP
Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-glucose <=> Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP
Quercetin 3-O-glucoside + UDP-D-xylose <=> Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside] + UDP
Myricetin + S-Adenosyl-L-methionine <=> Laricitrin + S-Adenosyl-L-homocysteine
Laricitrin + S-Adenosyl-L-methionine <=> Syringetin + S-Adenosyl-L-homocysteine
Chrysanthemin + Malonyl-CoA <=> Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA
Chrysanthemin + UDP-L-rhamnose <=> Cyanidin 3-O-rutinoside + UDP
Cyanidin 3-O-rutinoside + UDP-glucose <=> Cyanidin 3-O-rutinoside 5-O-beta-D-glucoside + UDP
Naringenin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Naringin + UDP
Apigenin 7-O-beta-D-glucoside + Malonyl-CoA <=> Apigenin 7-(6''-malonylglucoside) + CoA
Apigenin <=> Vitexin
Vitexin <=> Vitexin 2''-O-beta-L-rhamnoside
Vitexin 2''-O-beta-L-rhamnoside + S-Adenosyl-L-methionine <=> Isoswertisin 2''-rhamnoside + S-Adenosyl-L-homocysteine
Apigenin <=> Isovitexin
Apigenin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Apigenin 7-O-neohesperidoside + UDP
Luteolin 7-O-glucuronide + UDP-glucuronate <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + UDP
Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + UDP-glucuronate <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + UDP
Luteolin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Scolymoside + UDP
2-Aminomalonate semialdehyde <=> Aminoacetaldehyde + CO2
1,2,4-Trichlorobenzene + NADH + H+ + Oxygen <=> 3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3,4,6-Trichlorocatechol + NADH + H+
3,4,6-Trichlorocatechol + Oxygen <=> 2,3,5-Trichloro-cis,cis-muconate
2,3,5-Trichloro-cis,cis-muconate <=> 2,5-Dichloro-carboxymethylenebut-2-en-4-olide + Hydrochloric acid
2,5-Dichloro-carboxymethylenebut-2-en-4-olide + H2O <=> 2,5-Dichloro-4-oxohex-2-enedioate
D-Ribose 1,5-bisphosphate + ATP <=> 5-Phospho-alpha-D-ribose 1-diphosphate + ADP
alpha-D-Ribose 1-phosphate <=> D-Ribose 1,5-bisphosphate
trans-4-Carboxymethylenebut-2-en-4-olide + H2O <=> 2-Maleylacetate
3-Chlorocatechol + Oxygen <=> 2-Chloro-cis,cis-muconate
2-Chloro-cis,cis-muconate <=> trans-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid
Quinate + NADP+ <=> 3-Dehydroquinate + NADPH + H+
Shikimate + NAD+ <=> 3-Dehydroshikimate + NADH + H+
2,5-Dichloro-4-oxohex-2-enedioate + 2 NADH + 2 H+ <=> 2-Chloro-3-oxoadipate + Hydrochloric acid + 2 NAD+
1,2,4-Trichlorobenzene <=> 1,4-Dichlorobenzene
1,4-Dichlorobenzene <=> Chlorobenzene
Hydroquinone + NADPH + H+ + Oxygen <=> Benzene-1,2,4-triol + NADP+ + H2O
4-Hydroxyaniline + H2O <=> p-Benzoquinone + Ammonia
Benzene-1,2,4-triol <=> 2-Hydroxy-1,4-benzoquinone
2-Hydroxy-1,4-benzoquinone <=> p-Benzoquinone + H2O
2-Chloro-3-oxoadipate <=> Chloroacetic acid + Succinate
Chlorobenzene + Oxygen + NADH + H+ <=> 3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3-Chlorocatechol + NADH + H+
D-Xylulose 5-phosphate + Thiamin diphosphate <=> alpha,beta-Dihydroxyethyl-TPP + D-Glyceraldehyde 3-phosphate
alpha,beta-Dihydroxyethyl-TPP + Formaldehyde <=> Thiamin diphosphate + Glycerone
Sedoheptulose 7-phosphate + Thiamin diphosphate <=> alpha,beta-Dihydroxyethyl-TPP + D-Ribose 5-phosphate
3-Hexaprenyl-4-hydroxybenzoate + Oxygen <=> 3-Hexaprenyl-4,5-dihydroxybenzoate + H2O
3-Hexaprenyl-4-hydroxy-5-methoxybenzoate <=> 2-Hexaprenyl-6-methoxyphenol + CO2
UDP-6-sulfoquinovose + 1,2-Diacyl-sn-glycerol <=> Sulfoquinovosyldiacylglycerol + UDP
S-Adenosyl-L-methionine + N-Methylethanolamine phosphate <=> S-Adenosyl-L-homocysteine + Phosphodimethylethanolamine
S-Adenosyl-L-methionine + Phosphodimethylethanolamine <=> S-Adenosyl-L-homocysteine + Choline phosphate
Ethanolamine phosphate + H2O <=> Ethanolamine + Orthophosphate
Choline phosphate + H2O <=> Choline + Orthophosphate
sn-Glycerol 3-phosphate + Acyl-CoA <=> 2-Acyl-sn-glycerol 3-phosphate + CoA
1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 4-phosphate + Orthophosphate
Tetrabromobisphenol A <=> Tribromobisphenol A + Hydrobromic acid
Tribromobisphenol A <=> Dibromobisphenol A + Hydrobromic acid
Dibromobisphenol A <=> Monobromobisphenol A + Hydrobromic acid
Monobromobisphenol A <=> Bisphenol A + Hydrobromic acid
2 Bisphenol A <=> 4-Methyl-2,4-bis-(p-hydroxyphenyl)pent-1-ene
Bisphenol A <=> 5-Hydroxybisphenol A
5-Hydroxybisphenol A <=> 4,5-Bisphenol-o-quinone
Bisphenol A + NADH + H+ + Oxygen <=> 1,2-Bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O
Bisphenol A + NADH + H+ + Oxygen <=> 2,2-Bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O
1,2-Bis(4-hydroxyphenyl)-2-propanol <=> 4,4'-Dihydroxy-alpha-methylstilbene + H2O
4,4'-Dihydroxy-alpha-methylstilbene + Oxygen <=> 4-Hydroxybenzaldehyde + 4'-Hydroxyacetophenone
2,2-Bis(4-hydroxyphenyl)-1-propanol <=> 2,2-Bis(4-hydroxyphenyl)-propanoic acid
2,2-Bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + Oxygen <=> 2,3-Bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O
2,3-Bis(4-hydroxyphenyl)-1,2-propanediol <=> 4-Hydroxyphenacyl alcohol + 4-Hydroxybenzoate
4-Ethylphenol + NADPH + H+ + Oxygen <=> 1-(4'-Hydroxyphenyl)ethanol + NADP+ + H2O
1-(4'-Hydroxyphenyl)ethanol + NAD+ <=> 4'-Hydroxyacetophenone + NADH + H+
4'-Hydroxyacetophenone + NADPH + H+ + Oxygen <=> 4-Hydroxyphenyl acetate + NADP+ + H2O
4-Hydroxyphenyl acetate + H2O <=> Hydroquinone + Acetate
UDP-N-acetyl-D-galactosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-D-galactosaminuronic acid + 2 NADH + 2 H+
Coproporphyrinogen III + 2 S-Adenosyl-L-methionine <=> Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine
Divinylprotochlorophyllide + NADPH + H+ <=> Protochlorophyllide + NADP+
2-Hydroxyhepta-2,4-dienedioate + H2O <=> 2,4-Dihydroxyhept-2-enedioate
2-Naphthoic acid <=> 5,6,7,8-Tetrahydro-2-naphthoic acid
5,6,7,8-Tetrahydro-2-naphthoic acid <=> Decahydro-2-naphthoic acid
5,6,7,8-Tetrahydro-2-naphthoic acid <=> cis-2-Carboxycyclohexyl-acetic acid
Tetralin <=> 5,6,7,8-Tetrahydro-2-naphthoic acid
2-Naphthoic acid + FADH2 + Oxygen <=> 1-Hydroxy-2-naphthoate + FAD + H2O
2-Methylnaphthalene + Fumarate <=> 2-Naphtylmethylsuccinic acid
2-Naphtylmethylsuccinic acid + Succinyl-CoA <=> Naphthyl-2-methyl-succinyl-CoA + Succinate
Naphthyl-2-methyl-succinyl-CoA <=> Naphthyl-2-methylene-succinyl-CoA + 2 H+
Naphthyl-2-methylene-succinyl-CoA + H2O <=> Naphthyl-2-hydroxymethyl-succinyl CoA
Naphthyl-2-hydroxymethyl-succinyl CoA <=> Naphthyl-2-oxomethyl-succinyl-CoA + 2 H+
Naphthyl-2-oxomethyl-succinyl-CoA + CoA <=> 2-Naphthoyl-CoA + Succinyl-CoA
1-Methylnaphthalene + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene + NAD+
cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene + NAD+ <=> 1,2-Dihydroxy-8-methylnaphthalene + NADH + H+
1,2-Dihydroxy-8-methylnaphthalene + Oxygen <=> 2-Hydroxy-8-methylchromene-2-carboxylate
2-Hydroxy-8-methylchromene-2-carboxylate <=> 2-Hydroxy-3-methylbenzalpyruvate
2-Hydroxy-3-methylbenzalpyruvate + H2O <=> 3-Methylsalicylaldehyde + Pyruvate
3-Methylsalicylaldehyde + NAD+ + H2O <=> 3-Methylsalicylate + NADH + H+
3-Methylsalicylate + Oxygen + NADH + H+ <=> 2,3-Dihydroxytoluene + NAD+ + CO2 + H2O
1-Methylnaphthalene + Oxygen + NADH + H+ <=> 1-Hydroxymethylnaphthalene + NAD+ + H2O
1-Hydroxymethylnaphthalene + NAD+ <=> 1-Naphthaldehyde + NADH + H+
1-Naphthaldehyde + NAD+ + H2O <=> 1-Naphthoic acid + NADH + H+
1-Naphthoic acid + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+
cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene <=> 1,2-Dihydroxy-8-carboxynaphthalene
1,2-Dihydroxy-8-carboxynaphthalene + Oxygen <=> 2-Carboxy-2-hydroxy-8-carboxychromene
2-Carboxy-2-hydroxy-8-carboxychromene <=> 2-Hydroxy-3-carboxybenzalpyruvate
2-Hydroxy-3-carboxybenzalpyruvate + H2O <=> 3-Formylsalicylic acid + Pyruvate
3-Formylsalicylic acid + Oxygen + H2O <=> 2-Hydroxyisophthalic acid + Hydrogen peroxide
2-Hydroxyisophthalic acid <=> Salicylate + CO2
2-Methylnaphthalene + Oxygen + NADH + H+ <=> (2-Naphthyl)methanol + NAD+ + H2O
(2-Naphthyl)methanol + NAD+ <=> 2-Naphthaldehyde + NADH + H+
2-Naphthaldehyde + NAD+ + H2O <=> 2-Naphthoic acid + NADH + H+
2-Naphthaldehyde <=> 4-Formylsalicylic acid
(2-Naphthyl)methanol + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene + NAD+
cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene + NAD+ <=> 1,2-Dihydroxy-7-hydroxymethylnaphthalene + NADH + H+
1,2-Dihydroxy-7-hydroxymethylnaphthalene + Oxygen <=> 2-Hydroxy-7-hydroxymethylchromene-2-carboxylate
2-Hydroxy-7-hydroxymethylchromene-2-carboxylate <=> 2-Hydroxy-4-hydroxymethylbenzalpyruvate
2-Hydroxy-4-hydroxymethylbenzalpyruvate + H2O <=> 4-Hydroxymethylsalicylaldehyde + Pyruvate
4-Hydroxymethylsalicylaldehyde + NAD+ + H2O <=> 4-Hydroxymethylsalicylate + NADH + H+
4-Hydroxymethylsalicylate + Oxygen + NADH + H+ <=> 4-Hydroxymethylcatechol + NAD+ + H2O + CO2
2-Methylnaphthalene + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene + NAD+
cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene <=> 4-Methylsalicylate
4-Methylsalicylate + Oxygen + NADH + H+ <=> 4-Methylcatechol + NAD+ + H2O + CO2
N-Cyclohexylformamide + H2O <=> Cyclohexylamine + Formate
(3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+
5-Carboxy-2-pentenoyl-CoA + H2O <=> (3S)-3-Hydroxyadipyl-CoA
Adipyl-CoA + FAD <=> 5-Carboxy-2-pentenoyl-CoA + FADH2
Adipate + CoA + ATP <=> Adipyl-CoA + AMP + Diphosphate
Cyclohexane + Oxygen + NADH + H+ <=> Cyclohexanol + NAD+ + H2O
Zeaxanthin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Antheraxanthin + 2 Oxidized ferredoxin + H2O
Antheraxanthin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Violaxanthin + 2 Oxidized ferredoxin + H2O
Violaxanthin <=> Neoxanthin
Neoxanthin <=> 9'-cis-Neoxanthin
Violaxanthin <=> 9-cis-Violaxanthin
9-cis-Violaxanthin <=> 9'-cis-Neoxanthin
9'-cis-Neoxanthin + Oxygen <=> Xanthoxin + C25-Allenic-apo-aldehyde
9-cis-Violaxanthin + Oxygen <=> Xanthoxin + C25-Epoxy-apo-aldehyde
Xanthoxin + NAD+ <=> Abscisic aldehyde + NADH + H+
Xanthoxin <=> Xanthoxic acid
Xanthoxic acid <=> Abscisate
Abscisic aldehyde + H2O + Oxygen <=> Abscisate + Hydrogen peroxide
Abscisic aldehyde <=> Abscisic alcohol
Abscisic alcohol <=> Abscisate
all-trans-Neurosporene <=> alpha-Zeacarotene
alpha-Zeacarotene <=> delta-Carotene
delta-Carotene <=> alpha-Carotene
Lycopene <=> delta-Carotene
alpha-Carotene <=> Lutein
2-Chloro-4-hydroxy-6-amino-1,3,5-triazine + H2O <=> Ammelide + Hydrochloric acid
Ammelide + H2O <=> Cyanuric acid + Ammonia
Melamine + H2O <=> Ammeline + Ammonia
Ammeline + H2O <=> Ammelide + Ammonia
Cyromazine + H2O <=> N-Cyclopropylammeline + Ammonia
N-Cyclopropylammeline + H2O <=> N-Cyclopropylammelide + Ammonia
N-Cyclopropylammelide + H2O <=> Cyanuric acid + Cyclopropylamine
3-Oxopropanoate <=> Acetaldehyde + CO2
Formate + ATP + 5'-Phosphoribosylglycinamide <=> ADP + Orthophosphate + 5'-Phosphoribosyl-N-formylglycinamide
Formate + ATP + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
ATP + Lombricine <=> ADP + N-Phospholombricine
L-Glutamate + L-Aspartate 4-semialdehyde <=> 2-Oxoglutarate + L-2,4-Diaminobutanoate
L-2,4-Diaminobutanoate + Acetyl-CoA <=> N(gamma)-Acetyldiaminobutyrate + CoA
N(gamma)-Acetyldiaminobutyrate <=> H2O + Ectoine
Sulfoacetaldehyde + NAD+ + H2O <=> Sulfoacetate + NADH + H+
2-Hydroxyethanesulfonate + 2 Ferricytochrome c <=> Sulfoacetaldehyde + 2 Ferrocytochrome c + 2 H+
Glutathione + Formaldehyde <=> S-(Hydroxymethyl)glutathione
S-(Hydroxymethyl)glutathione + NAD+ <=> S-Formylglutathione + NADH + H+
trans-Hex-2-enoyl-CoA + NADPH + H+ <=> Hexanoyl-CoA + NADP+
GDP-D-mannose + G00011 <=> GDP + G10694
2-Oxobutanoate + CoA <=> Propanoyl-CoA + Formate
3-Hydroxyaminophenol <=> Aminohydroquinone
cis,cis-Muconate <=> (S)-5-Oxo-2,5-dihydrofuran-2-acetate
(S)-5-Oxo-2,5-dihydrofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate
34a-Deoxy-rifamycin W <=> Rifamycin W
Rifamycin W <=> Rifamycin W-hemiacetal
Rifamycin W <=> Rifamycin Z
Rifamycin W-hemiacetal <=> Demethyl-desacetyl-rifamycin S
Rifamycin Z <=> Demethyl-desacetyl-rifamycin S
Demethyl-desacetyl-rifamycin S <=> 27-O-Demethyl-25-O-desacetylrifamycin SV
Acetyl-CoA + 27-O-Demethyl-25-O-desacetylrifamycin SV <=> CoA + 27-O-Demethylrifamycin SV
S-Adenosyl-L-methionine + 27-O-Demethylrifamycin SV <=> S-Adenosyl-L-homocysteine + Rifamycin
Rifamycin <=> Rifamycin S
Naphthalene + NADPH + Oxygen + H+ <=> (1R,2S)-Naphthalene 1,2-oxide + NADP+ + H2O
Naphthalene + NADPH + Oxygen + H+ <=> (1S,2R)-Naphthalene 1,2-oxide + NADP+ + H2O
(1R,2S)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene
(1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene
(1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene
(1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene <=> (1R)-Hydroxy-(2R)-N-acetyl-L-cysteinyl-1,2-dihydronaphthalene
(1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene <=> (1R)-N-Acetyl-L-cysteinyl-(2R)-hydroxy-1,2-dihydronaphthalene
(1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene <=> (1R,2R)-3-[(1,2-Dihydro-2-hydroxy-1-naphthalenyl)thio]-2-oxopropanoic acid
(1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene <=> (1S)-Hydroxy-(2S)-N-acetyl-L-cysteinyl-1,2-dihydronaphthalene
(1R,2S)-Naphthalene 1,2-oxide <=> 1-Naphthol
(1S,2R)-Naphthalene 1,2-oxide <=> 1-Naphthol
(1R,2S)-Naphthalene 1,2-oxide <=> 2-Naphthol
(1S,2R)-Naphthalene 1,2-oxide <=> 2-Naphthol
(1R,2S)-Naphthalene 1,2-oxide + H2O <=> 1,2-Dihydronaphthalene-1,2-diol
(1S,2R)-Naphthalene 1,2-oxide + H2O <=> 1,2-Dihydronaphthalene-1,2-diol
1,2-Dihydronaphthalene-1,2-diol + NADP+ <=> Naphthalene-1,2-diol + NADPH + H+
1,2-Dihydronaphthalene-1,2-diol + NADPH + Oxygen + H+ <=> 1,2-Dihydroxy-3,4-epoxy-1,2,3,4-tetrahydronaphthalene + NADP+ + H2O
Naphthalene-1,2-diol <=> 1,2-Naphthoquinone
1-Naphthol <=> 1,4-Dihydroxynaphthalene
1,4-Dihydroxynaphthalene <=> 1,4-Naphthoquinone
2-Naphthol + NADPH + Oxygen + H+ <=> Naphthalene-1,2-diol + NADP+ + H2O
1-Nitronaphthalene + NADPH + Oxygen + H+ <=> 1-Nitronaphthalene-7,8-oxide + NADP+ + H2O
1-Nitronaphthalene + NADPH + Oxygen + H+ <=> 1-Nitronaphthalene-5,6-oxide + NADP+ + H2O
1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
1-Nitronaphthalene-5,6-oxide + H2O <=> 1-Nitro-5,6-dihydroxy-dihydronaphthalene
1-Nitronaphthalene <=> 1-Nitrosonaphthalene
1-Nitrosonaphthalene <=> N-Hydroxy-1-aminonaphthalene
N-Hydroxy-1-aminonaphthalene <=> 1-Naphthylamine
5,6-Epoxytetraene + H2O <=> Lipoxin A4
5,6-Epoxytetraene + H2O <=> Lipoxin B4
2 Glutathione + 5(S)-HPETE <=> Glutathione disulfide + 5(S)-HETE + H2O
2 Glutathione + 15(S)-HPETE <=> Glutathione disulfide + (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + H2O
Hepoxilin A3 + H2O <=> Trioxilin A3
Hepoxilin B3 + H2O <=> Trioxilin B3
Arachidonate + Oxygen <=> 12(R)-HPETE
12(S)-HPETE <=> Hepoxilin A3
12(S)-HPETE <=> Hepoxilin B3
Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
15(S)-HPETE <=> 15H-11,12-EETA
15(S)-HPETE <=> 11H-14,15-EETA
15H-11,12-EETA + H2O <=> 11,12,15-THETA
11H-14,15-EETA + H2O <=> 11,14,15-THETA
Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19(S)-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
Arachidonate + Oxygen <=> 11(R)-HPETE
Arachidonate + Oxygen + NADPH + H+ <=> 14,15-EET + NADP+ + H2O
Arachidonate + Oxygen <=> 9(S)-HPETE
Arachidonate + Oxygen + NADPH + H+ <=> 11,12-EET + NADP+ + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 8,9-EET + NADP+ + H2O
Arachidonate + Oxygen + NADPH + H+ <=> 5,6-EET + NADP+ + H2O
Arachidonate + Oxygen <=> 8(S)-HPETE
Arachidonate + Oxygen + NADPH + H+ <=> 16(R)-HETE + NADP+ + H2O
Linoleate + Oxygen + NADPH + H+ <=> 9(10)-EpOME + NADP+ + H2O
Linoleate + Oxygen + NADPH + H+ <=> 12(13)-EpOME + NADP+ + H2O
Linoleate + Oxygen <=> 9(S)-HPODE
13(S)-HODE + NAD+ <=> 13-OxoODE + NADH + H+
GDP-4-dehydro-6-deoxy-D-mannose <=> GDP-4-keto-6-L-deoxygalactose
GDP-4-keto-6-L-deoxygalactose + NADPH + H+ <=> GDP-L-fucose + NADP+
Linoleate + Oxygen <=> 8(R)-HPODE
8(R)-HPODE <=> (7S,8S)-DiHODE
Linoleate + Reduced acceptor + Oxygen <=> (6Z,9Z,12Z)-Octadecatrienoic acid + Acceptor + 2 H2O
Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate
Bromobenzene + NADPH + Oxygen + H+ <=> Bromobenzene-3,4-oxide + NADP+ + H2O
Delta-12-Prostaglandin J2 <=> 15-Deoxy-Delta12,14-PGJ2 + H2O
Bromobenzene + NADPH + Oxygen + H+ <=> Bromobenzene-2,3-oxide + NADP+ + H2O
Bromobenzene-3,4-oxide + Glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene
Bromobenzene-2,3-oxide + Glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene
Bromobenzene-3,4-oxide + H2O <=> Bromobenzene-3,4-dihydrodiol
Bromobenzene-2,3-oxide + H2O <=> Bromobenzene-2,3-dihydrodiol
Bromobenzene-3,4-oxide <=> 4-Bromophenol
Bromobenzene-2,3-oxide <=> 2-Bromophenol
4-Bromophenol + NADPH + Oxygen + H+ <=> 4-Bromophenol-2,3-epoxide + NADP+ + H2O
4-Bromophenol-2,3-epoxide <=> 4-Bromocatechol
4-Bromocatechol <=> 4-Bromo-3,5-cyclohexadiene-1,2-dione
Bromobenzene-3,4-dihydrodiol <=> 4-Bromocatechol
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-9,10-oxide + NADP+ + H2O
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-7,8-oxide + NADP+ + H2O
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-4,5-oxide + NADP+ + H2O
Benzo[a]pyrene-7,8-oxide + H2O <=> Benzo[a]pyrene-7,8-dihydrodiol
Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene
Benzo[a]pyrene-7,8-dihydrodiol + Glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O
Benzo[a]pyrene-7,8-dihydrodiol + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide + NADP+ + H2O
Benzo[a]pyrene-9,10-oxide <=> 9-Hydroxybenzo[a]pyrene
9-Hydroxybenzo[a]pyrene + NADPH + Oxygen + H+ <=> 9-Hydroxybenzo[a]pyrene-4,5-oxide + NADP+ + H2O
1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> 2,2-Dichloroacetaldehyde + NADP+ + H2O
1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> 1,1-Dichloroethylene epoxide + NADP+ + H2O
1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> Chloroacetyl chloride + NADP+ + H2O
2,2-Dichloroacetaldehyde + Glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl glutathione
1,1-Dichloroethylene epoxide + Glutathione <=> 2-(S-Glutathionyl)acetyl chloride + Hydrochloric acid
Chloroacetyl chloride + Glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric acid
2-(S-Glutathionyl)acetyl chloride + Glutathione <=> 2-(S-Glutathionyl)acetyl glutathione + Hydrochloric acid
2,2-Dichloroacetaldehyde + H2O <=> 2,2-Dichloro-1,1-ethanediol
Chloroacetyl chloride + H2O <=> Chloroacetic acid
2-(S-Glutathionyl)acetyl chloride + H2O <=> 2-S-Glutathionyl acetate
Trichloroethene + NADPH + Oxygen + H+ <=> TCE epoxide + NADP+ + H2O
Trichloroethene + NADPH + Oxygen + H+ <=> Chloral + NADP+ + H2O
Trichloroethene + Glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric acid
Chloral + H2O <=> Chloral hydrate
TCE epoxide <=> Dichloroacetyl chloride
Dichloroacetyl chloride <=> Dichloroacetate
Chloral hydrate + NAD+ <=> Trichloroacetate + NADH + H+
Chloral hydrate + NADH + H+ <=> Trichloroethanol + NAD+ + H2O
Trichloroethanol + UDP-glucuronate <=> Trichloroethanol glucuronide + UDP
Trichloroethanol + 2 NADPH + 2 Oxygen + 2 H+ <=> Trichloroacetate + 2 NADP+ + 3 H2O
14,15-EET + H2O <=> 14,15-DHET
11,12-EET + H2O <=> 11,12-DHET
8,9-EET + H2O <=> 8,9-DHET
5,6-EET + H2O <=> 5,6-DHET
1,2-Dibromoethane + NADPH + Oxygen + H+ <=> 2-Bromoacetaldehyde + NADP+ + H2O + Hydrobromic acid
1,2-Dibromoethane + Glutathione + H+ <=> Glutathione episulfonium ion + 2 Hydrobromic acid
S-(Formylmethyl)glutathione <=> Thiodiacetic acid
S-(Formylmethyl)glutathione <=> Thiodiacetic acid sulfoxide
2-Bromoacetaldehyde + Glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic acid
Glutathione episulfonium ion + H2O <=> S-(2-Hydroxyethyl)glutathione
S-(2-Hydroxyethyl)glutathione <=> S-(2-Hydroxyethyl)-N-acetyl-L-cysteine
Glutathione episulfonium ion <=> S-[2-(N7-Guanyl)ethyl]-N-acetyl-L-cysteine
S-(Formylmethyl)glutathione <=> S-(2-Hydroxyethyl)glutathione
12(13)-EpOME + H2O <=> 12,13-DHOME
9(10)-EpOME + H2O <=> 9,10-DHOME
Trichloroacetate <=> Dichloroacetate
2-(S-Glutathionyl)acetyl glutathione + H2O <=> 2-S-Glutathionyl acetate + Glutathione
3-Dehydro-L-gulonate 6-phosphate + H+ <=> L-Xylulose 5-phosphate + CO2
3-Dehydro-L-gulonate + ATP <=> 3-Dehydro-L-gulonate 6-phosphate + ADP
Oplophorus luciferin + Oxygen <=> Oxidized Oplophorus luciferin + hn + CO2
Dolichyl phosphate D-mannose + G00149 <=> Dolichyl phosphate + G00140
G02047 + 2 UDP-N-acetyl-D-glucosamine <=> G06302 + 2 UDP
Sorbitol 6-phosphate + NAD+ <=> D-Fructose 6-phosphate + NADH + H+
D-Arabitol + NAD+ <=> D-Ribulose + NADH + H+
Mannitol + NAD+ <=> D-Mannose + NADH + H+
(2R)-3-Sulfolactate + NAD+ <=> 3-Sulfopyruvate + NADH + H+
(2R)-3-Sulfolactate + NADP+ <=> 3-Sulfopyruvate + NADPH + H+
Isopregnanolone + NADP+ <=> 5alpha-Pregnane-3,20-dione + NADPH + H+
S-(Hydroxymethyl)glutathione + NADP+ <=> S-Formylglutathione + NADPH + H+
2'-Deoxymugineic acid + NAD+ <=> 3''-Deamino-3''-oxonicotianamine + NADH + H+
2'-Deoxymugineic acid + NADP+ <=> 3''-Deamino-3''-oxonicotianamine + NADPH + H+
D-Arabitol + NADP+ <=> D-Xylulose + NADPH + H+
D-Arabitol + NADP+ <=> D-Ribulose + NADPH + H+
L-Iditol + NAD+ <=> L-Sorbose + NADH + H+
D-Glucose + NADP+ <=> D-Glucono-1,5-lactone + NADPH + H+
D-threo-Aldose + NAD+ <=> D-threo-Aldono-1,5-lactone + NADH + H+
3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADP+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH + H+
dTDP-galactose + 2 NADP+ + H2O <=> dTDP-D-galacturonate + 2 NADPH + 2 H+
L-2-Hydroxyphytanate + Oxygen <=> 2-Oxophytanate + Hydrogen peroxide
Xylitol + Oxygen <=> D-Xylose + Hydrogen peroxide
2-Keto-D-gluconic acid + Acceptor <=> 2,5-Didehydro-D-gluconate + Reduced acceptor
Pyridoxine + Acceptor <=> Isopyridoxal + Reduced acceptor
(R)-2-Hydroxyacid + Acceptor <=> 2-Oxo acid + Reduced acceptor
Fluoroacetaldehyde + NAD+ + H2O <=> Fluoroacetate + NADH + H+
CO + H2O + 2 Oxidized ferredoxin <=> CO2 + 2 Reduced ferredoxin + 2 H+
Aldehyde + H2O + 2 Oxidized ferredoxin <=> Carboxylate + 2 Reduced ferredoxin + 2 H+
D-Glyceraldehyde 3-phosphate + H2O + 2 Oxidized ferredoxin <=> 3-Phospho-D-glycerate + 2 H+ + 2 Reduced ferredoxin
3-Methyl-2-oxobutanoic acid + CoA + 2 Oxidized ferredoxin <=> 2-Methylpropanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+
Indolepyruvate + CoA + Oxidized ferredoxin <=> S-2-(Indol-3-yl)acetyl-CoA + CO2 + Reduced ferredoxin
Acyl-CoA + NADP+ <=> trans-2,3-Dehydroacyl-CoA + NADPH + H+
all-trans-13,14-Dihydroretinol + Acceptor <=> Retinol + Reduced acceptor
L-Aspartate + H2O + NAD+ <=> Oxaloacetate + Ammonia + NADH + H+
L-Aspartate + H2O + NADP+ <=> Oxaloacetate + Ammonia + NADPH + H+
D-Amino acid + H2O + Acceptor <=> 2-Oxo acid + Ammonia + Reduced acceptor
Taurine + H2O + Acceptor <=> Sulfoacetaldehyde + Ammonia + Reduced acceptor
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
(R)-Canadine + 2 NADP+ <=> Berberine + 2 NADPH + 2 H+
(R)-6-Hydroxynicotine + H2O + Oxygen <=> 6-Hydroxypseudooxynicotine + Hydrogen peroxide
NADH + H+ + Oxygen <=> NAD+ + Hydrogen peroxide
NADPH + H+ + Oxygen <=> NADP+ + Hydrogen peroxide
Hydrazine + 4 Ferricytochrome c <=> Nitrogen + 4 Ferrocytochrome c
2 CoA + NADP+ <=> CoA-disulfide + NADPH + H+
AMP + Sulfite + Thioredoxin disulfide <=> Adenylyl sulfate + Thioredoxin
2 Thiosulfate + Decylubiquinone <=> Tetrathionate + Decylubiquinol
Violaxanthin + Ascorbate <=> Antheraxanthin + Dehydroascorbate + H2O
Antheraxanthin + Ascorbate <=> Zeaxanthin + Dehydroascorbate + H2O
Hydrogen + NADP+ <=> NADPH + H+
Hydrogen + Acceptor <=> Reduced acceptor
Pentane-2,4-dione + Oxygen <=> Acetate + Methylglyoxal
Gibberellin A44 + 2-Oxoglutarate + Oxygen <=> Gibberellin A19 + Succinate + CO2
2'-Deoxymugineic acid + 2-Oxoglutarate + Oxygen <=> Mugineic acid + Succinate + CO2
Mugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxymugineic acid + Succinate + CO2
2'-Deoxymugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxy-2'-deoxymugineic acid + Succinate + CO2
Benzoate + NADH + H+ + Oxygen <=> 1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
N,N-Dihydroxy-L-tyrosine <=> (E)-4-Hydroxyphenylacetaldehyde oxime + CO2 + H2O
2,3,5,6-Tetrachlorophenol + NADPH + H+ + Oxygen <=> Tetrachlorohydroquinone + NADP+ + H2O
Ketosteroid + NADPH + H+ + Oxygen <=> Steroid ester + NADP+ + H2O
Ketosteroid + NADPH + H+ + Oxygen <=> Steroid lactone + NADP+ + H2O
Propylene + NADH + H+ + Oxygen <=> 1,2-Epoxypropane + NAD+ + H2O
Glyceocarpin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-Glyceollin II + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Glyceocarpin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glyceollin III + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
4-Glyceollidin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-Glyceollin I + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Liquiritigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Licodione + [Oxidized NADPH---hemoprotein reductase] + H2O
Phenylacetone + NADPH + H+ + Oxygen <=> Benzyl acetate + NADP+ + H2O
Abscisate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 8'-Hydroxyabscisate + [Oxidized NADPH---hemoprotein reductase] + H2O
Lithocholic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Murideoxycholic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
3alpha,7alpha-Dihydroxy-5beta-cholestane + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + [Oxidized NADPH---hemoprotein reductase] + H2O
Taurochenodeoxycholate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taurohyocholate + [Oxidized NADPH---hemoprotein reductase] + H2O
Lithocholic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Hyodeoxycholate + [Oxidized NADPH---hemoprotein reductase] + H2O
Cholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cerebrosterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Cerebrosterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (24S)-Cholest-5-ene-3beta,7alpha,24-triol + [Oxidized NADPH---hemoprotein reductase] + H2O
25-Hydroxycholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cholest-5-ene-3beta,7alpha,25-triol + [Oxidized NADPH---hemoprotein reductase] + H2O
Alkanesulfonate + Reduced FMN + Oxygen <=> Aldehyde + FMN + Sulfite + H2O
L-Phenylalanine + Tetrahydrobiopterin + Oxygen <=> L-Tyrosine + 4a-Hydroxytetrahydrobiopterin
L-Tyrosine + Tetrahydrobiopterin + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin
L-Tryptophan + Tetrahydrobiopterin + Oxygen <=> 5-Hydroxy-L-tryptophan + 4a-Hydroxytetrahydrobiopterin
1-Aminocyclopropane-1-carboxylate + Ascorbate + Oxygen <=> Ethylene + Cyanide ion + Dehydroascorbate + CO2 + 2 H2O
Lathosterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 7-Dehydrocholesterol + 2 Ferricytochrome b5 + 2 H2O
Tetradecanoyl-CoA + NADPH + H+ + Oxygen <=> (E)-11-Tetradecenoyl-CoA + NADP+ + 2 H2O
Tetradecanoyl-CoA + NADPH + H+ + Oxygen <=> (Z)-11-Tetradecenoyl-CoA + NADP+ + 2 H2O
Cholesterol + Reduced acceptor + Oxygen <=> 25-Hydroxycholesterol + Acceptor + H2O
Deoxycholic acid + FAD + H2O <=> Cholic acid + FADH2
6-Hydroxynicotinate + H2O + Oxygen <=> 2,6-Dihydroxynicotinate + Hydrogen peroxide
Phenylacetyl-CoA + H2O + 2 Quinone <=> Phenylglyoxylyl-CoA + 2 Hydroquinone
Naringenin chalcone + Oxygen <=> Aureusidin + H2O
2 Eriodictyol chalcone + Oxygen <=> 2 Aureusidin + 2 H2O
Acetyl phosphate + Ammonia + Thioredoxin disulfide + H2O <=> Glycine + Orthophosphate + Thioredoxin
Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O <=> Sarcosine + Orthophosphate + Thioredoxin
Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O <=> Betaine + Orthophosphate + Thioredoxin
Selenite + H2O + Acceptor <=> Selenate + Reduced acceptor
3,3',5'-Triiodo-L-thyronine + Iodide + Acceptor + H+ <=> Thyroxine + Reduced acceptor
S-Adenosyl-L-methionine + Adenine in rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N6-methyladenine
S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N1-methylguanine
S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N2-methylguanine
S-Adenosyl-L-methionine + gamma-Tocopherol <=> S-Adenosyl-L-homocysteine + alpha-Tocopherol
S-Adenosyl-L-methionine + Uroporphyrinogen III <=> S-Adenosyl-L-homocysteine + Precorrin 1
S-Adenosyl-L-methionine + Precorrin 1 <=> S-Adenosyl-L-homocysteine + Precorrin 2
S-Adenosyl-L-methionine + [Cytochrome c]-arginine <=> S-Adenosyl-L-homocysteine + [Cytochrome c]-N(omega)-methylarginine
S-Adenosyl-L-methionine + Isoeugenol <=> S-Adenosyl-L-homocysteine + Methylisoeugenol
S-Adenosyl-L-methionine + Palmatine + 2 NADPH <=> S-Adenosyl-L-homocysteine + Corydaline + 2 NADP+
S-Adenosyl-L-methionine + Isoliquiritigenin <=> S-Adenosyl-L-homocysteine + 2'-O-Methylisoliquiritigenin
S-Adenosyl-L-methionine + Sarcosine <=> S-Adenosyl-L-homocysteine + N,N-Dimethylglycine
S-Adenosyl-L-methionine + N,N-Dimethylglycine <=> S-Adenosyl-L-homocysteine + Betaine
Carbamoyl phosphate + N-Acetylornithine <=> Orthophosphate + N-Acetyl-L-citrulline
L-Threonine + Fluoroacetaldehyde <=> Acetaldehyde + 4-Fluoro-L-threonine
2 alpha,alpha'-Trehalose 6-mycolate <=> alpha,alpha-Trehalose + alpha,alpha'-Trehalose 6,6'-bismycolate
Acetyl-CoA + alpha-2,8-Linked polymer of sialic acid <=> CoA + Polysialic acid acetylated at O-9
3 Malonyl-CoA + N-Methylanthraniloyl-CoA <=> 4 CoA + 1,3-Dihydroxy-N-methylacridone + 3 CO2 + H2O
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein <=> Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O
Acetyl-CoA + 10-Desacetyltaxuyunnanin C <=> CoA + Taxuyunnanin C
Acetyl-CoA + 3 Malonyl-CoA + NADPH + H+ <=> 6-Methylsalicylate + 4 CoA + 3 CO2 + NADP+ + H2O
Malonyl-CoA + Anthocyanidin 3-O-beta-D-glucoside <=> CoA + Anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside)
NDP-glucose + D-Fructose <=> NDP + Sucrose
GDP-mannose + di-trans,poly-cis-Undecaprenyl phosphate <=> GDP + D-Mannosyl-1-phosphoundecaprenol
UDP-N-acetyl-alpha-D-glucosamine + 6-(alpha-D-Mannosyl)-beta-D-mannosyl-R <=> UDP + 6-(2-[N-Acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Mannosyl-R <=> UDP + 4-(N-Acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R
UDP-glucose + cis-Zeatin <=> UDP + O-beta-D-Glucopyranosyl-cis-zeatin
NDP-glucose + Amylose <=> NDP + Amylose
1,4-Dihydroxy-2-naphthoyl-CoA + H2O <=> 1,4-Dihydroxy-2-naphthoate + CoA
2-Succinylbenzoyl-CoA <=> 1,4-Dihydroxy-2-naphthoyl-CoA + H2O
2-alpha-D-Glucosyl-D-glucose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate
alpha,alpha-Trehalose + Orthophosphate <=> alpha-D-Glucose + D-Glucose 1-phosphate
UDP-glucose + Anthocyanin <=> UDP + Anthocyanin 3'-O-beta-D-glucoside
all-trans-Octaprenyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + all-trans-Nonaprenyl diphosphate
ATP + Cobinamide <=> Triphosphate + Adenosyl cobinamide
di-trans,poly-cis-Decaprenyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + di-trans,poly-cis-Undecaprenyl diphosphate
Prephytoene diphosphate <=> all-trans-Phytoene + Diphosphate
Dimethylallyl diphosphate + 3,6,9-Trihydroxypterocarpan <=> Diphosphate + Glyceocarpin
Dimethylallyl diphosphate + 3,6,9-Trihydroxypterocarpan <=> Diphosphate + 4-Glyceollidin
all-trans-Nonaprenyl diphosphate + 4-Hydroxybenzoate <=> Diphosphate + 3-Nonaprenyl-4-hydroxybenzoate
O-Phospho-L-serine + Hydrogen sulfide <=> L-Cysteine + Orthophosphate
alpha,omega-Diamine + 2-Oxoglutarate <=> omega-Aminoaldehyde + L-Glutamate
L-Arogenate + 2-Oxoglutarate <=> Prephenate + L-Glutamate
Nicotianamine + 2-Oxoglutarate <=> 3''-Deamino-3''-oxonicotianamine + L-Glutamate
dGTP + Depurinated DNA <=> Deoxyribose triphosphate + DNA containing guanine
ATP + myo-Inositol <=> ADP + 1D-myo-Inositol 3-phosphate
5-Amino-6-(5'-phospho-D-ribitylamino)uracil + H2O <=> 5-Amino-6-(1-D-ribitylamino)uracil + Orthophosphate
D-Ribulose 5-phosphate <=> L-3,4-Dihydroxybutan-2-one 4-phosphate + Formate
RNA + Orthophosphate <=> RNA + NDP
tRNA + Orthophosphate <=> tRNA + NDP
3'-Phosphoadenylyl sulfate + Glycolithocholate <=> Adenosine 3',5'-bisphosphate + Sulfoglycolithocholate
3'-Phosphoadenylyl sulfate + Dermatan <=> Adenosine 3',5'-bisphosphate + Dermatan 6'-sulfate
3'-Phosphoadenylyl sulfate + Glycochenodeoxycholate <=> Adenosine 3',5'-bisphosphate + Glycochenodeoxycholate 7-sulfate
Formyl-CoA + Oxalate <=> Formate + Oxalyl-CoA
1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Carboxylate
Feruloyl-polysaccharide + H2O <=> Ferulate + Polysaccharide
1-Acylglycerol + H2O <=> Glycerol + Carboxylate
Phenylglyoxylyl-CoA + H2O <=> alpha-Oxo-benzeneacetic acid + CoA
Deoxycholoyl-CoA + Cholic acid <=> Deoxycholic acid + Choloyl-CoA
Choloyl-CoA + H2O <=> Cholic acid + CoA
5'-Ribonucleotide + H2O <=> Ribonucleoside + Orthophosphate
sn-Glycerol 1-phosphate + H2O <=> Glycerol + Orthophosphate
1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3-phosphate + Orthophosphate
N8-Acetylspermidine + H2O <=> Acetate + Spermidine
N-(2-Phenylethyl)-acetamide + H2O <=> Phenethylamine + Acetate
ATP + Adenosyl cobyrinate hexaamide + (R)-1-Aminopropan-2-ol <=> ADP + Orthophosphate + Adenosyl cobinamide
N-Benzylformamide + H2O <=> Formate + Benzylamine
GTP + 3 H2O <=> 2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 Orthophosphate
dCTP + 2 H2O <=> dUMP + Diphosphate + Ammonia
(R)-2-Haloacid + H2O <=> (S)-2-Hydroxyacid + Halide
(S)-2-Haloacid + H2O <=> (S)-2-Hydroxyacid + Halide
(R)-2-Haloacid + H2O <=> (R)-2-Hydroxyacid + Halide
2'-Hydroxybiphenyl-2-sulfinate + H2O <=> 2-Hydroxybiphenyl + Sulfite
4-Hydroxyphenylacetate + H+ <=> 4-Cresol + CO2
D-Dopachrome <=> 5,6-Dihydroxyindole + CO2
(3S)-3-Hydroxyacyl-CoA <=> (3E)-3-Enoyl-CoA + H2O
Carbamate <=> Ammonia + CO2
2,7,4'-Trihydroxyisoflavanone <=> Daidzein + H2O
7alpha,12alpha-Dihydroxy-3-oxochol-4-enoate <=> 12alpha-Hydroxy-3-oxochola-4,6-dienoate + H2O
alpha-Maltose <=> beta-Maltose
Violaxanthin <=> Capsorubin
Antheraxanthin <=> Capsanthin
Squalene <=> Diploptene
Squalene + H2O <=> Diplopterol
D-Glucose 6-phosphate <=> 1D-myo-Inositol 3-phosphate
ATP + Acid + Acyl-carrier protein <=> AMP + Diphosphate + Acyl-[acyl-carrier protein]
Alcohol + NAD+ <=> Aldehyde + NADH + H+
Alcohol + NADP+ <=> Aldehyde + NADPH + H+
(2S)-Flavanone + 2-Oxoglutarate + Oxygen <=> (2R,3R)-Dihydroflavonol + Succinate + CO2
S-Adenosyl-L-methionine + Catechol <=> S-Adenosyl-L-homocysteine + Guaiacol
S-Adenosyl-L-methionine + 4'-Hydroxyisoflavone <=> S-Adenosyl-L-homocysteine + 4'-Methoxyisoflavone
UDP-glucose + Isoflavone <=> UDP + Isoflavone 7-O-beta-D-glucoside
UDP-glucose + Flavanone <=> UDP + Flavanone 7-O-beta-D-glucoside
beta-D-Glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminylproteoglycan + UDP-N-acetyl-alpha-D-glucosamine <=> UDP + N-Acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminylproteoglycan
UDP-glucuronate + N-Acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosylproteoglycan <=> UDP + beta-D-Glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosylproteoglycan
UDP-glucuronate + N-Acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan <=> UDP + beta-D-Glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan
UDP-L-rhamnose + Flavanone 7-O-beta-D-glucoside <=> UDP + Flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside]
UDP-glucose + Flavonol <=> UDP + Flavonol 7-O-beta-D-glucoside
UDP-glucose + Flavonol 3-O-beta-D-glucoside <=> UDP + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
UDP-glucose + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside <=> UDP + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside
Nucleotide + Deoxynucleoside <=> Nucleoside + Deoxynucleoside 5'-phosphate
Phenyl acetate + H2O <=> Phenol + Acetate
myo-Inositol phosphate + H2O <=> myo-Inositol + Orthophosphate
Chalcone <=> Flavanone
(-)-Usnic acid + NADH + H+ <=> (6R)-2-Acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methyl-2,4-cyclohexadien-1-one + NAD+
D-Sorbitol + NADP+ <=> L-Sorbose + NADPH + H+
Pyranose + Acceptor <=> 2-Dehydropyranose + Reduced acceptor
Pyranoside + Acceptor <=> 3-Dehydropyranoside + Reduced acceptor
n-Alkanal + NAD+ <=> Alk-2-enal + NADH + H+
n-Alkanal + NADP+ <=> Alk-2-enal + NADPH + H+
2,3-cis-2R,3R-Flavan-3-ol + 2 NAD+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADH + H+
2,3-cis-2R,3R-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+
6-(2-Amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 Oxygen <=> PQQ + 2 Hydrogen peroxide + 2 H2O
Tetrahydropteridine + NAD+ <=> Dihydropteridine + NADH + H+
Tetrahydropteridine + NADP+ <=> Dihydropteridine + NADPH + H+
Glyceocarpin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glyceollin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
4-Glyceollidin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glyceollin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
NADH + H+ + Quinone <=> NAD+ + Hydroquinone
NADPH + H+ + Quinone <=> NADP+ + Hydroquinone
Prenyl-L-cysteine + Oxygen + H2O <=> Prenal + L-Cysteine + Hydrogen peroxide
1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide + Quinone <=> Nicotinamide-beta-riboside + Hydroquinone
D-Tryptophan + Oxygen <=> N-Formyl-D-kynurenine
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Oxygen <=> 3-(Methylthio)propanoate + Formate + CO
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Oxygen <=> 4-Methylthio-2-oxobutanoic acid + Formate
4 Sulfur + 4 H2O + Oxygen <=> 2 Hydrogen sulfide + 2 Sulfite
Leucocyanidin + 2-Oxoglutarate + Oxygen <=> cis-Dihydroquercetin + Succinate + CO2 + H2O
Flavanone + 2-Oxoglutarate + Oxygen <=> Flavone + Succinate + CO2 + H2O
Dihydroflavonol + 2-Oxoglutarate + Oxygen <=> Flavonol + Succinate + CO2 + H2O
Flavanone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3'-Hydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O
3'-Hydroxyflavanone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3',5'-Dihydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O
Isoflavone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxyisoflavone + [Oxidized NADPH---hemoprotein reductase] + H2O
Cholest-5-ene-3beta,26-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha,27-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Senecionine + NADPH + H+ + Oxygen <=> Senecionine N-oxide + NADP+ + H2O
(25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + Acceptor <=> (24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA + Reduced acceptor
S-Adenosyl-L-methionine + 7-Hydroxyisoflavone <=> S-Adenosyl-L-homocysteine + 7-Methoxyisoflavone
Phosphatidylethanolamine + L-Serine <=> Phosphatidylserine + Ethanolamine
Phosphatidylcholine + L-Serine <=> Phosphatidylserine + Choline
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate
1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycerol + Ethanolamine phosphate
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-Alkenyl-2-acylglycerol + Ethanolamine phosphate
1-(1-Alkenyl)-sn-glycero-3-phosphate + Acyl-CoA <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + CoA
2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + H2O <=> 1-Alkenyl-2-acylglycerol + Orthophosphate
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + Ethanolamine
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + Choline <=> Plasmenylcholine + Ethanolamine
1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate
1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphate + Ethanolamine
1-Alkyl-2-acylglycerol + CDP-choline <=> 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + CMP
2 Phosphatidylglycerol <=> Cardiolipin + Glycerol
S-Methyl-5-thio-D-ribulose 1-phosphate <=> 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O
2,3-Diketo-5-methylthiopentyl-1-phosphate <=> 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O <=> 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate
2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O <=> 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate
4-Methylthio-2-oxobutanoic acid + L-Glutamate <=> L-Methionine + 2-Oxoglutarate
UDP-N-acetyl-alpha-D-glucosamine + 3-beta-D-Glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein <=> UDP + alpha-N-Acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosylproteoglycan
6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O <=> 6-(alpha-D-Glucosaminyl)-1D-myo-inositol + Phosphatidate
Acetyl-CoA + Pyruvate + H2O <=> (R)-2-Methylmalate + CoA
Cephalosporin C + H2O + Oxygen <=> (7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + Ammonia + Hydrogen peroxide
(7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + Hydrogen peroxide <=> (7R)-7-(4-Carboxybutanamido)cephalosporanate + CO2 + H2O
(7R)-7-(4-Carboxybutanamido)cephalosporanate + H2O <=> 7-Aminocephalosporanic acid + Glutarate
Indole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Indolin-2-one + [Oxidized NADPH---hemoprotein reductase] + H2O
ATP + Aminoimidazole ribotide + HCO3- <=> ADP + Orthophosphate + 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole <=> 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
2-Amino-3-oxo-4-phosphonooxybutyrate <=> 3-Amino-2-oxopropyl phosphate + CO2
L-Aspartate + NADP+ <=> Iminoaspartate + NADPH + H+
Choline + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Betaine aldehyde + 2 H2O + 2 Oxidized ferredoxin
L-Aspartate + NAD+ <=> Iminoaspartate + NADH + H+
Heme + H2O + trans,trans-Farnesyl diphosphate <=> Heme O + Diphosphate
Heme O + H2O + 2 Acceptor <=> Heme A + 2 Reduced acceptor
Digalacturonate + H2O <=> 2 D-Galacturonate
ATP + L-Glutamate + Putrescine <=> ADP + Orthophosphate + gamma-L-Glutamylputrescine
gamma-L-Glutamylputrescine + H2O + Oxygen <=> gamma-Glutamyl-gamma-aminobutyraldehyde + Ammonia + Hydrogen peroxide
ATP + N-Methylanthranilate + CoA <=> AMP + Diphosphate + N-Methylanthraniloyl-CoA
gamma-Glutamyl-gamma-aminobutyraldehyde + NAD+ + H2O <=> 4-(L-gamma-Glutamylamino)butanoate + NADH + H+
gamma-Glutamyl-gamma-aminobutyraldehyde + NADP+ + H2O <=> 4-(L-gamma-Glutamylamino)butanoate + NADPH + H+
4-(L-gamma-Glutamylamino)butanoate + H2O <=> 4-Aminobutanoate + L-Glutamate
Phosphocreatine <=> Creatinine + Orthophosphate
Indolin-2-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3-Hydroxyindolin-2-one + [Oxidized NADPH---hemoprotein reductase] + H2O
3-Hydroxyindolin-2-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> HBOA + [Oxidized NADPH---hemoprotein reductase] + H2O
HBOA + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> DIBOA + [Oxidized NADPH---hemoprotein reductase] + H2O
UDP-glucose + DIBOA <=> UDP + DIBOA-glucoside
Campesterol <=> Campest-4-en-3beta-ol
Campest-4-en-3beta-ol + NAD+ <=> Campest-4-en-3-one + NADH + H+
Campest-4-en-3-one + NADPH + H+ <=> 5alpha-Campestan-3-one + NADP+
6-Oxocampestanol + Oxygen + NADPH <=> Cathasterone + NADP+ + H2O
Cathasterone + Oxygen + Reduced acceptor <=> Teasterone + H2O + Acceptor
p-Coumaroyl-CoA + Quinate <=> CoA + p-Coumaroyl quinic acid
5-O-Caffeoylshikimic acid + CoA <=> Caffeoyl-CoA + Shikimate
p-Coumaroyl-CoA <=> Caffeoyl-CoA
4-Hydroxycinnamyl aldehyde + NADPH + H+ <=> 4-Coumaryl alcohol + NADP+
Ferulate + NADPH + H+ + Oxygen <=> 5-Hydroxyferulic acid methyl ester + NADP+ + H2O
Sinapoyl aldehyde + NAD+ + H2O <=> Sinapate + NADH + H+
Sinapoyl aldehyde + NADP+ + H2O <=> Sinapate + NADPH + H+
5-Hydroxyconiferyl alcohol <=> 5-Hydroxy-guaiacyl lignin
Teasterone <=> 3-Dehydroteasterone
Campesterol + Oxygen + NADPH <=> 22alpha-Hydroxy-campesterol + NADP+ + H2O
22alpha-Hydroxy-campesterol <=> 22alpha-Hydroxy-campest-4-en-3-one
22alpha-Hydroxy-campest-4-en-3-one + NADPH + H+ <=> 22alpha-Hydroxy-5alpha-campestan-3-one + NADP+
6-Deoxocathasterone + Oxygen <=> 6-Deoxoteasterone + H2O
6-Deoxoteasterone <=> 3-Dehydro-6-deoxoteasterone
6-Deoxocastasterone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 6alpha-Hydroxy-castasterone + H2O + [Oxidized NADPH---hemoprotein reductase]
6alpha-Hydroxy-castasterone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Castasterone + 2 H2O + [Oxidized NADPH---hemoprotein reductase]
Campest-4-en-3-one + Oxygen + NADPH <=> 22alpha-Hydroxy-campest-4-en-3-one + NADP+ + H2O
5alpha-Campestan-3-one + Oxygen + NADPH <=> 22alpha-Hydroxy-5alpha-campestan-3-one + NADP+ + H2O
Campestanol + Oxygen + NADPH <=> 6-Deoxocathasterone + NADP+ + H2O
6-Deoxoteasterone + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> Teasterone + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase]
D-Glyceraldehyde 3-phosphate + D-Ribulose 5-phosphate + L-Glutamine <=> Pyridoxal phosphate + L-Glutamate + Orthophosphate + 3 H2O
3-Dehydro-6-deoxoteasterone + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> 3-Dehydroteasterone + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase]
6-Deoxotyphasterol + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> Typhasterol + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase]
Sulfur-carrier protein + ATP <=> Adenylyl-[sulfur-carrier protein] + Diphosphate
[Enzyme]-cysteine + L-Cysteine <=> [Enzyme]-S-sulfanylcysteine + L-Alanine
[Enzyme]-S-sulfanylcysteine + Adenylyl-[sulfur-carrier protein] + Reduced acceptor <=> AMP + Thiocarboxy-[sulfur-carrier protein] + [Enzyme]-cysteine + Acceptor
Glycine + Oxygen <=> Iminoglycine + Hydrogen peroxide
5alpha-Campestan-3-one <=> Campestanol
Campestanol + Oxygen + Reduced acceptor <=> 6alpha-Hydroxycampestanol + H2O + Acceptor
6alpha-Hydroxycampestanol <=> 6-Oxocampestanol
3-Dehydroteasterone <=> Typhasterol
Typhasterol + NADPH + H+ + Oxygen <=> Castasterone + NADP+ + H2O
Castasterone <=> Brassinolide
22alpha-Hydroxy-5alpha-campestan-3-one <=> 6-Deoxocathasterone
3-Dehydro-6-deoxoteasterone <=> 6-Deoxotyphasterol
6-Deoxotyphasterol + NADPH + H+ + Oxygen <=> 6-Deoxocastasterone + NADP+ + H2O
Geranylgeranyl diphosphate + Isopentenyl diphosphate <=> all-trans-Pentaprenyl diphosphate + Diphosphate
(2R)-O-Phospho-3-sulfolactate <=> Sulfite + Phosphoenolpyruvate
Spermidine + NAD+ <=> Dehydrospermidine + NADH + H+
N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ <=> [eIF5A-precursor]-deoxyhypusine + NAD+
Dehydrospermidine + [eIF5A-precursor]-lysine <=> N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + 1,3-Diaminopropane
N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + [eIF5A-precursor]-lysine <=> N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + [eIF5A-precursor]-lysine
Cycloartenol + S-Adenosyl-L-methionine <=> 24-Methylidenecycloartanol + S-Adenosyl-L-homocysteine
4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+ <=> 4alpha-Methylfecosterol + NADP+
4alpha-Methylfecosterol <=> 24-Methylenelophenol
Delta7-Avenasterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 5-Dehydroavenasterol + 2 Ferricytochrome b5 + 2 H2O
5-Dehydroavenasterol <=> Isofucosterol
Isofucosterol + NADPH + H+ <=> beta-Sitosterol + NADP+
beta-Sitosterol + NADPH + H+ + Oxygen <=> Stigmasterol + NADP+ + 2 H2O
Episterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 5-Dehydroepisterol + 2 Ferricytochrome b5 + 2 H2O
5-Dehydroepisterol <=> 24-Methylenecholesterol
24-Methylenecholesterol + NADPH + H+ <=> Campesterol + NADP+
4alpha-Methylzymosterol-4-carboxylate + NADP+ <=> 3-Keto-4-methylzymosterol + NADPH + H+ + CO2
3-Keto-4-methylzymosterol + NADPH + H+ <=> 4alpha-Methylzymosterol + NADP+
Fecosterol <=> Episterol
Zymosterol + NADPH + H+ <=> 5alpha-Cholest-8-en-3beta-ol + NADP+
14-Demethyllanosterol + NADPH + H+ <=> 4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+
Phytyl diphosphate + Homogentisate <=> 2-Methyl-6-phytylquinol + Diphosphate + CO2
2-Methyl-6-phytylquinol + S-Adenosyl-L-methionine <=> 2,3-Dimethyl-5-phytylquinol + S-Adenosyl-L-homocysteine
2,3-Dimethyl-5-phytylquinol <=> gamma-Tocopherol
2-Methyl-6-phytylquinol <=> delta-Tocopherol
delta-Tocopherol + S-Adenosyl-L-methionine <=> beta-Tocopherol + S-Adenosyl-L-homocysteine
Episterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 5,7,24(28)-Ergostatrienol + 2 Ferricytochrome b5 + 2 H2O
5,7,24(28)-Ergostatrienol + NADPH + H+ + Oxygen <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP+ + 2 H2O
7-Dehydrodesmosterol + NADPH + H+ <=> 7-Dehydrocholesterol + NADP+
beta-Tocopherol <=> alpha-Tocopherol
14-Demethyllanosterol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 4alpha-Methylzymosterol-4-carboxylate + 6 Ferricytochrome b5 + 4 H2O
15-cis-Phytoene <=> 9,9'-dicis-zeta-Carotene
9,9'-dicis-zeta-Carotene + 2 Quinone <=> 7,9,7',9'-tetracis-Lycopene + 2 Hydroquinone
7,9,7',9'-tetracis-Lycopene <=> Lycopene
17-O-Acetylajmaline + H2O <=> Ajmaline + Acetate
6-Hydroxypseudooxynicotine + Acceptor + H2O <=> 2,6-Dihydroxypseudooxynicotine + Reduced acceptor
2,6-Dihydroxypseudooxynicotine + H2O <=> 2,6-Dihydroxypyridine + 4-Methylaminobutyrate
gamma-Carotene + H2O <=> 1'-Hydroxy-gamma-carotene
1'-Hydroxy-gamma-carotene <=> 1'-Hydroxytorulene
Lycopene + Reduced acceptor + Oxygen <=> 3,4-Dehydrolycopene + Acceptor + H2O
Lycopene + H2O <=> 1-Hydroxy-1,2-dihydrolycopene
1-Hydroxy-1,2-dihydrolycopene + Acceptor <=> 3,4-Dehydrorhodopin + Reduced acceptor
3,4-Dehydrorhodopin + S-Adenosyl-L-methionine <=> Anhydrorhodovibrin + S-Adenosyl-L-homocysteine
Anhydrorhodovibrin + H2O <=> Rhodovibrin
Rhodovibrin <=> Hydroxyspirilloxanthin
Hydroxyspirilloxanthin + S-Adenosyl-L-methionine <=> Spirilloxanthin + S-Adenosyl-L-homocysteine
Spirilloxanthin + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> 2-Ketospirilloxanthin + 3 H2O + 4 Oxidized ferredoxin
2-Ketospirilloxanthin + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> 2,2'-Diketospirilloxanthin + 3 H2O + 4 Oxidized ferredoxin
1-Hydroxy-1,2-dihydrolycopene + S-Adenosyl-L-methionine <=> 3,4-Dihydroanhydrorhodovibrin + S-Adenosyl-L-homocysteine
3,4-Dihydroanhydrorhodovibrin + H2O <=> 3',4'-Dihydrorhodovibrin
3',4'-Dihydrorhodovibrin + S-Adenosyl-L-methionine <=> 3,4,3',4'-Tetrahydrospirilloxanthin + S-Adenosyl-L-homocysteine
alpha-Carotene + 2 Reduced ferredoxin + H+ + Oxygen <=> Zeinoxanthin + 2 Oxidized ferredoxin + H2O
Zeinoxanthin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Lutein + [Oxidized NADPH---hemoprotein reductase] + H2O
all-trans-Neurosporene + H2O <=> Chloroxanthin
Chloroxanthin + S-Adenosyl-L-methionine <=> 3,4-Dihydrospheroidene + S-Adenosyl-L-homocysteine
Chloroxanthin <=> Demethylspheroidene
Demethylspheroidene + S-Adenosyl-L-methionine <=> Spheroidene + S-Adenosyl-L-homocysteine
Spheroidene + H2O <=> Hydroxyspheroidene
Spheroidene + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> Spheroidenone + 3 H2O + 4 Oxidized ferredoxin
Hydroxyspheroidene + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> Hydroxyspheroidenone + 3 H2O + 4 Oxidized ferredoxin
Spheroidenone + H2O <=> Hydroxyspheroidenone
gamma-Carotene <=> 1',2'-Dihydro-gamma-carotene
gamma-Carotene + 2 Acceptor <=> Chlorobactene + 2 Reduced acceptor
gamma-Carotene <=> 1',2'-Dihydrochlorobactene
Chlorobactene + H2O <=> Hydroxychlorobactene
Hydroxychlorobactene <=> Hydroxychlorobactene glucoside
Hydroxychlorobactene glucoside <=> Hydroxychlorobactene glucoside ester
1'-Hydroxy-gamma-carotene <=> 1'-Hydroxy-gamma-carotene glucoside
1'-Hydroxy-gamma-carotene glucoside <=> 1'-Hydroxy-gamma-carotene glucoside ester
gamma-Carotene <=> Myxol
Myxol <=> 4-Ketomyxol
Myxol <=> 4-Hydroxymyxol
4-Ketomyxol <=> 4-Hydroxymyxol
gamma-Carotene <=> Deoxymyxol
Deoxymyxol <=> (2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside)
(2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside) <=> (3R,2'S)-Myxol 2'-(2,4-di-O-methyl-alpha-L-fucoside)
gamma-Carotene <=> (2'S)-Deoxymyxol 2'-alpha-L-fucoside
(2'S)-Deoxymyxol 2'-alpha-L-fucoside <=> (3R,2'S)-Myxol 2'-alpha-L-fucoside
(3R,2'S)-Myxol 2'-alpha-L-fucoside + 2 Reduced acceptor + 2 Oxygen <=> (3S,2'S)-4-Ketomyxol 2'-alpha-L-fucoside + 2 Acceptor + 3 H2O
beta-Carotene + 2 Reduced ferredoxin + H+ + Oxygen <=> beta-Cryptoxanthin + 2 Oxidized ferredoxin + H2O
beta-Cryptoxanthin + 2 Reduced ferredoxin + H+ + Oxygen <=> Zeaxanthin + 2 Oxidized ferredoxin + H2O
beta-Carotene + 4 Acceptor <=> Isorenieratene + 4 Reduced acceptor
Echinenone + 2 Reduced ferredoxin + H+ + Oxygen <=> 3'-Hydroxyechinenone + 2 Oxidized ferredoxin + H2O
Echinenone + 2 Reduced ferredoxin + H+ + Oxygen <=> 3-Hydroxyechinenone + 2 Oxidized ferredoxin + H2O
Echinenone + 2 Reduced acceptor + 2 Oxygen <=> Canthaxanthin + 2 Acceptor + 3 H2O
beta-Cryptoxanthin + 2 Reduced acceptor + 2 Oxygen <=> 3'-Hydroxyechinenone + 2 Acceptor + 3 H2O
beta-Cryptoxanthin + 2 Reduced acceptor + 2 Oxygen <=> 3-Hydroxyechinenone + 2 Acceptor + 3 H2O
3'-Hydroxyechinenone + 2 Reduced acceptor + 2 Oxygen <=> Phoenicoxanthin + 2 Acceptor + 3 H2O
3-Hydroxyechinenone + 2 Reduced acceptor + 2 Oxygen <=> Phoenicoxanthin + 2 Acceptor + 3 H2O
Canthaxanthin + 2 Reduced ferredoxin + H+ + Oxygen <=> Phoenicoxanthin + 2 Oxidized ferredoxin + H2O
3'-Hydroxyechinenone + 2 Reduced ferredoxin + H+ + Oxygen <=> Adonixanthin + 2 Oxidized ferredoxin + H2O
3-Hydroxyechinenone + 2 Reduced ferredoxin + H+ + Oxygen <=> Adonixanthin + 2 Oxidized ferredoxin + H2O
Zeaxanthin + 2 Reduced acceptor + 2 Oxygen <=> Adonixanthin + 2 Acceptor + 3 H2O
Phoenicoxanthin + 2 Reduced ferredoxin + H+ + Oxygen <=> Astaxanthin + 2 Oxidized ferredoxin + H2O
Adonixanthin + 2 Reduced acceptor + 2 Oxygen <=> Astaxanthin + 2 Acceptor + 3 H2O
Zeaxanthin + 2 UDP-glucose <=> Zeaxanthin diglucoside + 2 UDP
Abscisate + UDP-glucose <=> Abscisic acid glucose ester + UDP
8'-Hydroxyabscisate <=> Phaseic acid
Phaseic acid <=> Dihydrophaseic acid
beta-Cryptoxanthin <=> Thermocryptoxanthin
Thermocryptoxanthin <=> Thermozeaxanthin
Zeaxanthin <=> Thermozeaxanthin
Thermozeaxanthin <=> Thermobiszeaxanthin
(9S,10S)-10-Hydroxy-9-(phosphonooxy)octadecanoate + H2O <=> (9S,10S)-9,10-Dihydroxyoctadecanoate + Orthophosphate
Phytic acid + H2O <=> 1L-myo-Inositol 1,2,3,4,6-pentakisphosphate + Orthophosphate
Phytic acid + H2O <=> myo-Inositol pentakisphosphate + Orthophosphate
Cholesterol-5alpha,6alpha-epoxide + H2O <=> 3beta,5alpha,6beta-Cholestanetriol
L-Lysine + Oxygen + H2O <=> L-2-Aminoadipate 6-semialdehyde + Hydrogen peroxide + Ammonia
3-Methyl-2-oxobutanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxypropyl-ThPP + CO2
2-Methyl-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + Thiamin diphosphate
4-Methyl-2-oxopentanoate + Thiamin diphosphate <=> 3-Methyl-1-hydroxybutyl-ThPP + CO2
3-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
(S)-3-Methyl-2-oxopentanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxybutyl-ThPP + CO2
2-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
7-Aminomethyl-7-carbaguanine + 2 NADP+ <=> 7-Cyano-7-carbaguanine + 2 NADPH + 2 H+
L-Methionine + Thioredoxin disulfide + H2O <=> L-Methionine (S)-S-oxide + Thioredoxin
Peptide-L-methionine + Thioredoxin disulfide + H2O <=> Peptide-L-methionine (R)-S-oxide + Thioredoxin
L-Methionine + Thioredoxin disulfide + H2O <=> L-Methionine (R)-S-oxide + Thioredoxin
UDP-N-acetyl-D-galactosamine + Sda antigen - related compound <=> UDP + Sda antigen
UDP-N-acetyl-D-galactosamine + G00388 <=> UDP + G05309
UDP-N-acetyl-D-galactosamine + G05309 <=> UDP + G00704
Reactive black 5 + Hydrogen peroxide <=> Oxidized reactive black 5 + 2 H2O
LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate <=> 2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O
UDP-N-acetyl-D-galactosamine + G00025 <=> UDP + G13023
UDP-N-acetyl-D-galactosamine + G01977 <=> UDP + G13024
UDP-N-acetyl-D-galactosamine + G01941 <=> UDP + G13025
UDP-D-galactose + G00025 <=> UDP + G11136
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
UDP-N-acetyl-D-glucosamine + G13027 <=> UDP + G13026
Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + G13027
UDP-N-acetyl-D-glucosamine + G13026 <=> UDP + G13028
UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G10818
UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G13030
UDP-N-acetyl-D-glucosamine + G10818 <=> UDP + G13029
UDP-N-acetyl-D-glucosamine + G13030 <=> UDP + G13029
Protein-omega-N-(ADP-D-ribosyl)-L-arginine + H2O <=> ADP-ribose + Protein-L-arginine
cis-Stilbene oxide + H2O <=> (+)-(1R,2R)-1,2-Diphenylethane-1,2-diol
UDP-D-galactose + G00031 <=> UDP + G00032
3-Oxo-3-ureidopropanoate + H2O <=> Malonate + Urea
trans,trans-Farnesyl diphosphate <=> Amorpha-4,11-diene + Diphosphate
Geranyl diphosphate + H2O <=> (+)-Linalool + Diphosphate
Geranyl diphosphate + H2O <=> (-)-Linalool + Diphosphate
(2R)-3-Sulfolactate <=> Pyruvate + HSO3-
L-Cysteate + H2O <=> Pyruvate + HSO3- + Ammonia
6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol <=> 6-(alpha-D-Glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + 1,2-Diacyl-sn-glycerol
FAD <=> AMP + Riboflavin cyclic-4',5'-phosphate
(Z)-Phenylacetaldehyde oxime <=> Phenylacetonitrile + H2O
trans-Dec-2-enoyl-[acp] <=> cis-Dec-3-enoyl-[acp]
ATP + RNA(n) + RNA(m) <=> AMP + Diphosphate + RNA(n+m)
2 ATP + HCO3- + Ammonia <=> 2 ADP + Orthophosphate + Carbamoyl phosphate
ATP + L-Amino acid + L-Amino acid <=> ADP + Orthophosphate + L-Aminoacyl-L-amino acid
ATP + L-Glutamate + Histamine <=> Products of ATP breakdown + N(alpha)-gamma-L-Glutamylhistamine
6 ATP + 3 2,3-Dihydroxybenzoate + 3 L-Serine <=> Enterochelin + 6 AMP + 6 Diphosphate
ATP + L-Lysine + tRNA(Pyl) <=> AMP + Diphosphate + L-Lysyl-tRNA(Pyl)
trans,trans-Farnesyl diphosphate + H2O <=> (1E,4S,5E,7R)-Germacra-1(10),5-dien-11-ol + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-Germacrene D + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Germacrene A + Diphosphate
L-2,4-Diaminobutanoate <=> 1,3-Diaminopropane + CO2
D-Alanyl-D-alanine + H2O <=> 2 D-Alanine
2 trans,trans-Farnesyl diphosphate <=> 4,4'-Diapophytoene + 2 Diphosphate
4,4'-Diapophytoene + 3 FAD <=> 4,4'-Diaponeurosporene + 3 FADH2
4,4'-Diaponeurosporene + 3 Reduced acceptor + 3 Oxygen <=> 4,4'-Diaponeurosporenic acid + 3 Acceptor + 4 H2O
4,4'-Diaponeurosporenic acid <=> Glycosyl-4,4'-diaponeurosporenoate
Glycosyl-4,4'-diaponeurosporenoate <=> Staphyloxanthin
1-Hydroxy-2-naphthoate + Oxygen <=> (3Z)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate
UDP-glucuronate + NAD+ <=> UDP-L-Ara4O + CO2 + NADH + H+
UDP-L-Ara4O + L-Glutamate <=> UDP-L-Ara4N + 2-Oxoglutarate
10-Formyltetrahydrofolate + UDP-L-Ara4N <=> Tetrahydrofolate + UDP-L-Ara4FN
UDP-L-Ara4FN + di-trans,poly-cis-Undecaprenyl phosphate <=> Undecaprenyl phosphate alpha-L-Ara4FN + UDP
Undecaprenyl phosphate alpha-L-Ara4FN + H2O <=> Undecaprenyl phosphate alpha-L-Ara4N + Formate
Toluene-4-sulfonate + Oxygen <=> 4-Cresol + Sulfate
(S)-Mandelate + FMN <=> alpha-Oxo-benzeneacetic acid + Reduced FMN
3-Cresol + Oxygen + NADH + H+ <=> 3-Hydroxybenzyl alcohol + NAD+ + H2O
3-Hydroxybenzaldehyde + NADP+ + H2O <=> 3-Hydroxybenzoate + NADPH + H+
3-Hydroxybenzaldehyde + NAD+ + H2O <=> 3-Hydroxybenzoate + NADH + H+
Vanillate + Cob(I)alamin <=> 3,4-Dihydroxybenzoate + Methylcobalamin
beta-1,2,3,4,5,6-Hexachlorocyclohexane + H2O <=> beta-2,3,4,5,6-Pentachlorocyclohexanol + Hydrochloric acid
beta-2,3,4,5,6-Pentachlorocyclohexanol + H2O <=> beta-2,3,5,6-Tetrachloro-1,4-cyclohexanediol + Hydrochloric acid
Protein N(pi)-phospho-L-histidine + Ascorbate <=> Protein histidine + L-Ascorbate 6-phosphate
GDP-mannose <=> GDP-L-gulose
GDP-L-gulose <=> GDP-L-galactose
beta-L-Galactose 1-phosphate + H2O <=> L-Galactose + Orthophosphate
L-Galactose + NAD+ <=> L-Galactono-1,4-lactone + NADH + H+
L-Galactonate + NADP+ <=> D-Galacturonate + NADPH + H+
L-Ascorbate 6-phosphate + H2O <=> 3-Dehydro-L-gulonate 6-phosphate
GDP-L-galactose + D-Mannose 1-phosphate <=> beta-L-Galactose 1-phosphate + GDP-mannose
Ascorbate + 2 Ferricytochrome c <=> Dehydroascorbate + 2 Ferrocytochrome c + 2 H+
L-Galactono-1,4-lactone + H2O <=> L-Galactonate
1,6-Naphthalenedisulfonic acid + Oxygen <=> 1,2-Dihydroxynaphthalene-6-sulfonate + Sulfite
2,6-Naphthalenedisulfonic acid + Oxygen <=> 1,2-Dihydroxynaphthalene-6-sulfonate + Sulfite
1,2-Dihydroxynaphthalene-6-sulfonate + Oxygen <=> (Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate
(Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate + 2 H2O <=> 5-Sulfosalicylate + Pyruvate
5-Sulfosalicylate + Oxygen <=> 2,5-Dihydroxybenzoate + Sulfate
Anthracene + Oxygen + 2 H+ + 2 e- <=> Anthracene-9,10-dihydrodiol
Anthracene-9,10-dihydrodiol <=> 9,10-Dihydroxyanthracene + 2 H+
9,10-Dihydroxyanthracene <=> Anthraquinone + 2 H+
3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate <=> 1,2-Dihydrophthalic acid
3-Hydroxy-2-naphthoate + Oxygen <=> 3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate
4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid + 2 H2O <=> 3-Hydroxy-2-naphthoate + Pyruvate
4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid <=> 6,7-Benzocoumarin
1,2-Anthracenediol <=> 1-Methoxy-2-hydroxyanthracene
2,3-Dihydroxynaphthalene <=> Salicylate
3-Hydroxy-2-naphthoate <=> 2,3-Dihydroxynaphthalene
Phenylboronic acid + Oxygen <=> Phenol + Boric acid
1-Naphthalenesulfonic acid + Oxygen <=> Naphthalene-1,2-diol + Sulfite
2-Naphthalenesulfonic acid + Oxygen <=> Naphthalene-1,2-diol + Sulfite
Aniline + Oxygen <=> Catechol + Ammonia
1,2-Anthracenediol + Oxygen <=> 4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid
1,2-Anthracenediol + Oxygen <=> 3-(2-Carboxyvinyl)naphthalene-2-carboxylic acid
1,2-Dihydrophthalic acid + NAD+ <=> Phthalate + NADH + H+
Anthracene + Oxygen + NADH + H+ <=> Anthracene-cis-1,2-dihydrodiol + NAD+
Anthracene-cis-1,2-dihydrodiol + NAD+ <=> 1,2-Anthracenediol + NADH + H+
Nitrobenzene + Oxygen + NADH + H+ <=> Catechol + Nitrite + NAD+
Phenanthrene-9,10-oxide <=> 9-Hydroxyphenanthrene
trans-9(S),10(S)-Dihydrodiolphenanthrene <=> 9-Hydroxyphenanthrene + H2O
Salicylate + NADH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NAD+ + H2O
Salicylate + NADPH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NADP+ + H2O
Liquiritigenin + NADPH + H+ + Oxygen <=> 6,7,4'-Trihydroxyflavanone + NADP+ + H2O
Liquiritigenin + 2-Oxoglutarate + Oxygen <=> 7,4'-Dihydroxyflavone + Succinate + CO2 + H2O
(3Z)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate + H2O <=> 2-Carboxybenzaldehyde + Pyruvate
7,4'-Dihydroxyflavone + 2 NADPH + 2 H+ + Oxygen <=> 2,7,4'-Trihydroxyisoflavanone + 2 NADP+ + H2O
6,7,4'-Trihydroxyflavanone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 2,6,7,4'-Tetrahydroxyisoflavanone + H2O + [Oxidized NADPH---hemoprotein reductase]
2,6,7,4'-Tetrahydroxyisoflavanone <=> 4',6,7-Trihydroxyisoflavone
4',6,7-Trihydroxyisoflavone <=> Glycitein
Glycitein + UDP-glucose <=> Glycitin + UDP
Glycitin + Malonyl-CoA <=> Malonylglycitin + CoA
Daidzein + UDP-glucose <=> Daidzin + UDP
Daidzin + Malonyl-CoA <=> Malonyldaidzin + CoA
S-Adenosyl-L-methionine + 2,7,4'-Trihydroxyisoflavanone <=> S-Adenosyl-L-homocysteine + 2,7-Dihydroxy-4'-methoxyisoflavanone
2,7-Dihydroxy-4'-methoxyisoflavanone <=> Formononetin + H2O
Daidzein + S-Adenosyl-L-methionine <=> Isoformononetin + S-Adenosyl-L-homocysteine
Daidzein <=> Anhydroglycinol
Anhydroglycinol <=> Coumestrol
o-Nitrobenzoate + 2 NADPH + 2 H+ <=> o-Hydroxylaminobenzoate + 2 NADP+ + H2O
2'-Hydroxydihydrodaidzein + NADPH + H+ <=> 3,9-Dihydroxypterocarpan + NADP+ + H2O
Formononetin + UDP-glucose <=> Ononin + UDP
o-Hydroxylaminobenzoate <=> 3-Hydroxyanthranilate
Ononin + Malonyl-CoA <=> Formononetin 7-O-glucoside-6''-O-malonate + CoA
Formononetin 7-O-glucoside-6''-O-malonate <=> Ononin
Ononin <=> Formononetin
o-Hydroxylaminobenzoate + 2 H+ <=> Anthranilate + H2O
2'-Hydroxyformononetin <=> 7-Hydroxy-2',4',5'-trimethoxyisoflavone
7-Hydroxy-2',4',5'-trimethoxyisoflavone <=> 9-Demethylmunduserone
(-)-Vestitone + NADPH + H+ <=> 7,2'-Dihydroxy-4'-methoxy-isoflavanol + NADP+
7,2'-Dihydroxy-4'-methoxy-isoflavanol <=> Medicarpin + H2O
Medicarpin + NADPH + H+ <=> (-)-Vestitol + NADP+
Medicarpin + UDP-glucose <=> (-)-Medicocarpin + UDP
(-)-Medicocarpin + Malonyl-CoA <=> Medicarpin 3-O-glucoside-6'-malonate + CoA
Medicarpin 3-O-glucoside-6'-malonate <=> (-)-Medicocarpin
(-)-Medicocarpin <=> Medicarpin
Calycosin <=> Rotenone
Calycosin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pseudobaptigenin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Pseudobaptigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2',7-Dihydroxy-4',5'-methylenedioxyisoflavone + [Oxidized NADPH---hemoprotein reductase] + H2O
2',7-Dihydroxy-4',5'-methylenedioxyisoflavone + NADPH + H+ <=> (+)-Sophorol + NADP+
(+)-Sophorol + NADPH + H+ <=> (+)-Maackiain + NADP+ + H2O
(+)-Maackiain <=> (+)-6a-Hydroxymaackiain
(+)-6a-Hydroxymaackiain + S-Adenosyl-L-methionine <=> Pisatin + S-Adenosyl-L-homocysteine
2',7-Dihydroxy-4',5'-methylenedioxyisoflavone + NADPH + H+ <=> (-)-Sophorol + NADP+
(-)-Sophorol + NADPH + H+ <=> (-)-Maackiain + NADP+ + H2O
(-)-Maackiain + UDP-glucose <=> Trifolirhizin + UDP
Trifolirhizin + Malonyl-CoA <=> (-)-Maackiain-3-O-glucosyl-6''-O-malonate + CoA
(-)-Maackiain-3-O-glucosyl-6''-O-malonate <=> Trifolirhizin
Trifolirhizin <=> (-)-Maackiain
Genistein 7-O-beta-D-glucoside + Malonyl-CoA <=> Malonylgenistin + CoA
Malonyl-CoA + Palmitoyl-CoA <=> 3-Oxostearoyl-CoA + CoA + CO2
3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+
3-Hydroxyoctadecanoyl-CoA <=> (2E)-Octadecenoyl-CoA + H2O
(2E)-Octadecenoyl-CoA + NADPH + H+ <=> Stearoyl-CoA + NADP+
Hexadecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxostearoyl-[acp] + Acyl-carrier protein + CO2
3-Oxostearoyl-[acp] + NADPH + H+ <=> (R)-3-Hydroxyoctadecanoyl-[acp] + NADP+
(R)-3-Hydroxyoctadecanoyl-[acp] <=> (2E)-Octadecenoyl-[acp] + H2O
(2E)-Octadecenoyl-[acp] + NADH + H+ <=> Octadecanoyl-[acyl-carrier protein] + NAD+
Octanoyl-[acp] + [Lipoyl-carrier protein]-L-lysine <=> [Protein]-N6-(octanoyl)-L-lysine + Acyl-carrier protein
[Protein]-N6-(octanoyl)-L-lysine + [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster + 2 S-Adenosyl-L-methionine + 2 Reduced [2Fe-2S] ferredoxin + 8 H+ <=> [Protein]-N6-[(R)-dihydrolipoyl]-L-lysine + [Fe-S] cluster scaffold protein + 2 Hydrogen sulfide + 4 Fe2+ + 2 L-Methionine + 2 5'-Deoxyadenosine + 2 Oxidized [2Fe-2S] ferredoxin
Lipoyl-[acp] + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + Acyl-carrier protein
ATP + (R)-Lipoate <=> Diphosphate + Lipoyl-AMP
Lipoyl-AMP + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + AMP
Cobalt-precorrin 5A + H2O <=> Cobalt-precorrin 5B + Acetaldehyde
Cobalt-precorrin 5B + S-Adenosyl-L-methionine <=> Cobalt-precorrin 6 + S-Adenosyl-L-homocysteine
Cobalt-dihydro-precorrin 6 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 7 + S-Adenosyl-L-homocysteine + CO2
Cobalt-precorrin 7 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 8 + S-Adenosyl-L-homocysteine
Biochanin A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pratensein + [Oxidized NADPH---hemoprotein reductase] + H2O
Liquiritigenin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 2,7,4'-Trihydroxyisoflavanone + H2O + [Oxidized NADPH---hemoprotein reductase]
Naringenin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 2-Hydroxy-2,3-dihydrogenistein + H2O + [Oxidized NADPH---hemoprotein reductase]
Bromoxynil + 2 NADPH + 2 H+ + Oxygen <=> 2,6-Dibromohydroquinone + 2 NADP+ + Hydrogen cyanide + H2O
Bromoxynil + H2O <=> 3,5-Dibromo-4-hydroxybenzamide
2-Bromomaleylacetate + NADH + H+ <=> 2-Maleylacetate + NAD+ + Bromide
3,5-Dibromo-4-hydroxybenzamide + H2O <=> 3,5-Dibromo-4-hydroxybenzoate + Ammonia
3,5-Dibromo-4-hydroxybenzoate <=> 2,6-Dibromophenol
2,6-Dibromophenol <=> 2,6-Dibromohydroquinone
2,6-Dibromohydroquinone <=> 2-Bromomaleylacetate
22alpha-Hydroxy-campesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (22R,23R)-22,23-Dihydroxycampesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
22alpha-Hydroxy-campest-4-en-3-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (22R,23R)-22,23-Dihydroxy-campest-4-en-3-one + [Oxidized NADPH---hemoprotein reductase] + H2O
22alpha-Hydroxy-5alpha-campestan-3-one <=> 3-epi-6-Deoxocathasterone
(22R,23R)-22,23-Dihydroxycampesterol <=> (22R,23R)-22,23-Dihydroxy-campest-4-en-3-one
(22R,23R)-22,23-Dihydroxy-campest-4-en-3-one <=> 3-Dehydro-6-deoxoteasterone
22alpha-Hydroxy-5alpha-campestan-3-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3-Dehydro-6-deoxoteasterone + [Oxidized NADPH---hemoprotein reductase] + H2O
3-epi-6-Deoxocathasterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Deoxotyphasterol + [Oxidized NADPH---hemoprotein reductase] + H2O
4-Chloroaniline + Oxygen + 2 H+ <=> 4-Chlorocatechol + Ammonia
2,4-Dichloroaniline + 2 H+ <=> 4-Chloroaniline + Hydrochloric acid
3-Sulfocatechol + Oxygen + H2O <=> 2-Hydroxymuconate + Sulfite
(E)-Cinnamoyl-CoA + Phenyllactate <=> trans-Cinnamate + (R)-Phenyllactyl-CoA
3'-Phosphoadenylyl sulfate + Petromyzonol <=> Adenosine 3',5'-bisphosphate + Petromyzonol 24-sulfate
3'-Phosphoadenylyl sulfate + Scymnol <=> Adenosine 3',5'-bisphosphate + 5beta-Scymnol sulfate
Fluoren-9-one + Oxygen + H+ + NADH <=> 1-Hydro-1,1a-dihydroxy-9-fluorenone + NAD+
1-Hydro-1,1a-dihydroxy-9-fluorenone + H2O <=> 2,3-Dihydroxy-2'-carboxybiphenyl + 2 H+
2,3-Dihydroxy-2'-carboxybiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate
2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O <=> Phthalate + 2-Hydroxy-2,4-pentadienoate
3-Isochromanone <=> Catechol
(+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene <=> 3,4-Dihydroxyfluorene + 2 H+
Keratan sulfate + H2O <=> Keratan sulfate + G01945
G01945 + H2O <=> G01977 + Sulfate
G01977 + H2O <=> G13073 + D-Galactose
G13073 + H2O <=> G13074 + Sulfate
G13074 + H2O <=> G01391 + N-Acetyl-D-glucosamine
G13073 + H2O <=> G01391 + N-Acetyl-D-glucosamine 6-sulfate
Heparan sulfate + H2O <=> Heparan sulfate + G13034
G13034 + H2O <=> G13035 + Sulfate
G13035 + H2O <=> G13036 + L-Iduronic acid
G13036 + H2O <=> G13037 + Sulfate
Acetyl-CoA + G13037 <=> CoA + G13038
G13038 + H2O <=> G13039 + N-Acetyl-D-glucosamine
G13039 + H2O <=> G13040 + Sulfate
G13040 + H2O <=> G09660 + D-Glucuronate
G09660 + H2O <=> G02632 + Sulfate
Dermatan sulfate + H2O <=> Dermatan sulfate + G13041
G13041 + H2O <=> G13042 + Sulfate
G13042 + H2O <=> G12336 + L-Iduronic acid
G12336 + H2O <=> G13043 + Sulfate
G13043 + H2O <=> DWA-2 + N-Acetylgalactosamine
G12336 + H2O <=> DWA-2 + N-Acetylgalactosamine 4-sulfate
4-Coumarate <=> Caffeate
3-Chlorocatechol + Oxygen <=> 3-Chloro-2-hydroxymuconic semialdehyde
Cyclopropanecarboxylate + CoA + ATP <=> Cyclopropanecarboxyl-CoA + ADP + Orthophosphate
Cyclopropanecarboxyl-CoA <=> Crotonoyl-CoA
trans,trans-Farnesyl diphosphate <=> (+)-epi-Isozizaene + Diphosphate
Dihydrophloroglucinol + H2O <=> 3-Hydroxy-5-oxohexanoate
3-Hydroxy-5-oxohexanoate + Acetyl-CoA <=> 3-Hydroxy-5-oxohexanoyl-CoA + Acetate
3-Hydroxy-5-oxohexanoyl-CoA + CoA <=> (S)-3-Hydroxybutanoyl-CoA + Acetyl-CoA
1-Hydroxy-1,2-dihydrolycopene <=> Rhodopinal
Terephthalate + H2O <=> Benzoate + Carbonic acid
Thiobenzamide + Oxygen + NADPH + H+ <=> Thiobenzamide S-oxide + NADP+ + H2O
Thiobenzamide S-oxide + NADPH + H+ + Oxygen <=> Thiobenzamide S,S-dioxide + NADP+ + H2O
Thiobenzamide S,S-dioxide <=> Benzonitrile
(1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
delta-Carotene <=> epsilon-Carotene
Zeaxanthin <=> Caloxanthin
Caloxanthin <=> Nostoxanthin
Rhodopinal <=> Rhodopinal glucoside
Lycopene <=> (2S,2'S)-Oscillol
(2S,2'S)-Oscillol <=> (2S,2'S)-Oscillol 2,2'-di(alpha-L-fucoside)
Lycopene <=> R.g.-Keto I
R.g.-Keto I <=> R.g.-Keto III
R.g.-Keto I <=> Thiothece-474
Thiothece-474 + 2 Acceptor <=> Okenone + 2 Reduced acceptor
alpha-Carotene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> alpha-Cryptoxanthin + [Oxidized NADPH---hemoprotein reductase] + H2O
alpha-Cryptoxanthin + 2 Reduced ferredoxin + H+ + Oxygen <=> Lutein + 2 Oxidized ferredoxin + H2O
gamma-Carotene <=> (2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside)
Phenylacetonitrile + H2O <=> 2-Phenylacetamide
Phenylacetonitrile + 2 H2O <=> Phenylacetic acid + Ammonia
beta-Zeacarotene <=> 7,8-Dihydro-beta-carotene
beta-Carotene + 2 Acceptor <=> beta-Isorenieratene + 2 Reduced acceptor
beta-Isorenieratene + 2 Acceptor <=> Isorenieratene + 2 Reduced acceptor
Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid
Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid
(9Z,12Z,15Z)-Octadecatrienoic acid + Reduced acceptor + Oxygen <=> Stearidonic acid + Acceptor + 2 H2O
1'-Hydroxytorulene <=> Deinoxanthin
13(S)-HPOT <=> (9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid + H2O
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 9(S)-HPOT
9(S)-HPOT <=> 9,10-EOT + H2O
9,10-EOT <=> 10-OPDA
9(S)-HPOT <=> Colnelenic acid + H2O
9(S)-HPOT <=> 9-Oxononanoic acid + 3,6-Nonadienal
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 13(S)-HPOT
13(S)-HPOT <=> 12-Oxo-9(Z)-dodecenoic acid + 3-Hexenal
13(S)-HPOT <=> Etherolenic acid + H2O
12-Oxo-9(Z)-dodecenoic acid <=> Traumatin
Pelargonidin 3-O-glucoside + Caffeoyl-CoA <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-glucoside + UDP-glucose <=> Pelargonin + UDP
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) + UDP-glucose <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + UDP
Pelargonin + Caffeoyl-CoA <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + CoA
Pelargonidin 3-O-glucoside + UDP-glucose <=> Pelargonidin 3-O-sophoroside + UDP
Chrysanthemin + UDP-glucose <=> Cyanidin 3-O-sophoroside + UDP
Delphinidin 3-O-glucoside + UDP-glucose <=> Delphinidin 3-O-sophoroside + UDP
Pelargonin + p-Coumaroyl-CoA <=> Pelargonidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA
2-Naphthoyl-CoA + H2O <=> 2-Naphthoic acid + CoA
Cyanin + p-Coumaroyl-CoA <=> Cyanidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA
Delphin + p-Coumaroyl-CoA <=> Delphinidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=> Pelargonidin 3-O-3'',6''-O-dimalonylglucoside + CoA
Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=> Cyanidin 3-O-3'',6''-O-dimalonylglucoside + CoA
Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + Malonyl-CoA <=> Delphinidin 3-O-3'',6''-O-dimalonylglucoside + CoA
ATP + 8-[(1R,2R)-3-Oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate + CoA <=> AMP + Diphosphate + OPC8-CoA
OPC8-CoA + FAD <=> trans-2-Enoyl-OPC8-CoA + FADH2
3-Hydroxy-OPC8-CoA <=> trans-2-Enoyl-OPC8-CoA + H2O
3-Hydroxy-OPC8-CoA + NAD+ <=> 3-Oxo-OPC8-CoA + NADH + H+
OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA
OPC6-CoA + FAD <=> trans-2-Enoyl-OPC6-CoA + FADH2
3-Hydroxy-OPC6-CoA <=> trans-2-Enoyl-OPC6-CoA + H2O
3-Hydroxy-OPC6-CoA + NAD+ <=> 3-Oxo-OPC6-CoA + NADH + H+
OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA
OPC4-CoA + FAD <=> trans-2-Enoyl-OPC4-CoA + FADH2
3-Hydroxy-OPC4-CoA <=> trans-2-Enoyl-OPC4-CoA + H2O
3-Hydroxy-OPC4-CoA + NAD+ <=> 3-Oxo-OPC4-CoA + NADH + H+
(+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA
Cyanidin 3-O-rutinoside <=> Cyanidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Cyanidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Peonidin-3-(p-coumaroyl)-rutinoside-5-glucoside
(+)-7-Isojasmonic acid CoA + H2O <=> CoA + (+)-7-Isojasmonic acid
Delphinidin 3-O-glucoside + UDP-L-rhamnose <=> Tulipanin + UDP
Tulipanin <=> Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Petunidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Petunidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Malvidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Malvidin-3-(p-coumaroyl)-rutinoside-5-glucoside
Cyanidin <=> Cyanidin 5-O-glucoside
Cyanidin 5-O-glucoside <=> Cyanin
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + Malonyl-CoA <=> Malonylshisonin + CoA
Delphinidin 3-O-glucoside + UDP-glucose <=> Delphin + UDP
Delphin + UDP-glucose <=> Delphinidin 3,5,3'-triglucoside + UDP
Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-glucose <=> Delphinidin 3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside + UDP
Delphinidin 3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside + UDP-glucose <=> Ternatin C5 + UDP
Ternatin C5 <=> Ternatin A1
2 Geranylgeranyl diphosphate <=> all-trans-Phytoene + 2 Diphosphate
S-Adenosyl-L-methionine + Xanthosine <=> S-Adenosyl-L-homocysteine + 7-Methylxanthosine
7-Methylxanthosine + H2O <=> 7-Methylxanthine + D-Ribose
S-Adenosyl-L-methionine + 7-Methylxanthine <=> S-Adenosyl-L-homocysteine + Theobromine
S-Adenosyl-L-methionine + Theobromine <=> S-Adenosyl-L-homocysteine + Caffeine
S-Adenosyl-L-methionine + 1,7-Dimethylxanthine <=> S-Adenosyl-L-homocysteine + Caffeine
S-Adenosyl-L-methionine + 7-Methylxanthine <=> S-Adenosyl-L-homocysteine + 1,7-Dimethylxanthine
Delphinidin 3-glucoside 5-caffoyl-glucoside + UDP-glucose <=> Albireodelphin + UDP
Albireodelphin <=> Gentiodelphin
Delphinidin 3,5,3'-triglucoside <=> Gentiodelphin
Delphinidin 3-O-glucoside + Caffeoyl-CoA <=> Delphinidin 3-O-(6-caffeoyl-beta-D-glucoside) + CoA
Pelargonidin 3-O-glucoside + p-Coumaroyl-CoA <=> Pelargonidin 3-(6-p-coumaroyl)glucoside + CoA
Chrysanthemin + Caffeoyl-CoA <=> Cyanidin 3-(6-p-caffeoyl)glucoside + CoA
Delphinidin 3-O-glucoside + p-Coumaroyl-CoA <=> Delphinidin 3-(6-p-coumaroyl)glucoside + CoA
Pelargonin + Caffeoyl-CoA <=> Pelargonidin 3-glucoside 5-caffeoylglucoside + CoA
Cyanin + Caffeoyl-CoA <=> Cyanidin 3-glucoside 5-caffeoylglucoside + CoA
Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + UDP-glucuronate <=> Cyanidin-3-O-(6''-O-malonyl-2''-O-glucuronyl)glucoside + UDP
(9Z,12Z,15Z)-Octadecatrienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z,12Z,15Z)-Octadecatetraenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA + Oxygen <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + Hydrogen peroxide
(3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + H2O
(3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA + NADH + H+
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA
Delphinidin 3-O-glucoside + Malonyl-CoA <=> Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + CoA
Caffeine + NADPH + Oxygen + H+ <=> 1,7-Dimethylxanthine + NADP+ + Formaldehyde + H2O
1,7-Dimethylxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil
5-Acetylamino-6-formylamino-3-methyluracil <=> 5-Acetylamino-6-amino-3-methyluracil
1-Methylxanthine + H2O + Oxygen <=> 1-Methyluric acid + Hydrogen peroxide
1,7-Dimethylxanthine <=> 1-Methylxanthine
Delphin + Caffeoyl-CoA <=> Delphinidin 3-glucoside 5-caffoyl-glucoside + CoA
1,7-Dimethylxanthine <=> 1,7-Dimethyluric acid
(R,S)-Nicotine + Acceptor + H2O <=> (R)-6-Hydroxynicotine + Reduced acceptor
2,6-Dihydroxypseudooxynicotine <=> 2,6-Dihydroxy-N-methylmyosmine + H2O
2 2,3,6-Trihydroxypyridine + 2 Oxygen <=> Blue pigment + 2 Hydrogen peroxide
2,3,6-Trihydroxypyridine + Oxygen + H+ <=> Maleamate + 2 H+ + CO2
(6Z,9Z,12Z,15Z,18Z)-Tetracosapentaenoyl-CoA + Oxygen <=> (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexaenoyl-CoA + Hydrogen peroxide
(3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexaenoyl-CoA + H2O
(3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA + NADH + H+
(4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA
Caffeine + NADH + H+ + Oxygen <=> 1,7-Dimethylxanthine + NAD+ + Formaldehyde + H2O
Caffeine + NADH + H+ + Oxygen <=> Theobromine + NAD+ + Formaldehyde + H2O
Caffeine + NADPH + H+ + Oxygen <=> Theobromine + NADP+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADH + H+ + Oxygen <=> 7-Methylxanthine + NAD+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADPH + H+ + Oxygen <=> 7-Methylxanthine + NADP+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADH + H+ + Oxygen <=> 1-Methylxanthine + NAD+ + Formaldehyde + H2O
1,7-Dimethylxanthine + NADPH + H+ + Oxygen <=> 1-Methylxanthine + NADP+ + Formaldehyde + H2O
Theobromine + NADH + H+ + Oxygen <=> 7-Methylxanthine + NAD+ + Formaldehyde + H2O
Theobromine + NADPH + H+ + Oxygen <=> 7-Methylxanthine + NADP+ + Formaldehyde + H2O
Theobromine + NADH + H+ + Oxygen <=> 3-Methylxanthine + NAD+ + Formaldehyde + H2O
Theobromine + NADPH + H+ + Oxygen <=> 3-Methylxanthine + NADP+ + Formaldehyde + H2O
7-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O
7-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O
3-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O
3-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O
1-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O
1-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O
Caffeine + NADH + H+ + Oxygen <=> Theophylline + NAD+ + Formaldehyde + H2O
Caffeine + NADPH + H+ + Oxygen <=> Theophylline + NADP+ + Formaldehyde + H2O
Theophylline + NADH + H+ + Oxygen <=> 3-Methylxanthine + NAD+ + Formaldehyde + H2O
Theophylline + NADPH + H+ + Oxygen <=> 3-Methylxanthine + NADP+ + Formaldehyde + H2O
Theophylline + NADH + H+ + Oxygen <=> 1-Methylxanthine + NAD+ + Formaldehyde + H2O
Theophylline + NADPH + H+ + Oxygen <=> 1-Methylxanthine + NADP+ + Formaldehyde + H2O
1,7-Dimethylxanthine + Oxygen + H2O <=> 1,7-Dimethyluric acid + Hydrogen peroxide
Theobromine + H2O + Oxygen <=> 3,7-Dimethyluric acid + Hydrogen peroxide
7-Methylxanthine + Oxygen + H2O <=> 7-Methyluric acid + Hydrogen peroxide
Caffeine + Ubiquinone + H2O <=> 1,3,7-Trimethyluric acid + Ubiquinol
1,3,7-Trimethyluric acid + Oxygen + 2 H2O <=> 3,6,8-Trimethylallantoin + CO2 + Hydrogen peroxide
3,6,8-Trimethylallantoin + 2 H2O <=> N,N'-Dimethylurea + N-Methylurea + Glyoxylate
2,6-Dihydroxynicotinate + H2O + Oxygen <=> Maleamate + CO2 + Formate
6-Oxo-1,4,5,6-tetrahydronicotinate + 2 H2O <=> 2-Formylglutarate + Ammonia
2-Formylglutarate + NADH + H+ <=> (S)-2-(Hydroxymethyl)glutarate + NAD+
(S)-2-(Hydroxymethyl)glutarate <=> 2-Methyleneglutarate + H2O
Cinnamoyl-CoA + 3 Malonyl-CoA <=> Pinocembrin chalcone + 4 CoA + 3 CO2
Caffeoyl-CoA + 3 Malonyl-CoA <=> Eriodictyol chalcone + 4 CoA + 3 CO2
Feruloyl-CoA + 3 Malonyl-CoA <=> Homoeriodictyol chalcone + 4 CoA + 3 CO2
Pinocembrin chalcone <=> Pinocembrin
Eriodictyol chalcone <=> Eriodictyol
Homoeriodictyol chalcone <=> Homoeriodictyol
Pinocembrin + 2-Oxoglutarate + Oxygen <=> Pinobanksin + Succinate + CO2
Isoliquiritigenin <=> Butein
Butein <=> Butin
Liquiritigenin + 2-Oxoglutarate + Oxygen <=> Garbanzol + Succinate + CO2
Butin + 2-Oxoglutarate + Oxygen <=> Fustin + Succinate + CO2
5-Deoxyleucopelargonidin + NADP+ <=> Garbanzol + NADPH + H+
Fisetinidol-4beta-ol + NADP+ <=> Fustin + NADPH + H+
5-Deoxyleucopelargonidin <=> Garbanzol
Fisetinidol-4beta-ol <=> Fustin
Liquiritigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Butin + [Oxidized NADPH---hemoprotein reductase] + H2O
Naringenin chalcone + Dimethylallyl diphosphate <=> Desmethylxanthohumol + Diphosphate
Desmethylxanthohumol + S-Adenosyl-L-methionine <=> Xanthohumol + S-Adenosyl-L-homocysteine
Eriodictyol chalcone + Oxygen <=> Bracteatin + H2O
Naringenin chalcone + UDP-glucose <=> 2',4,4',6'-Tetrahydroxychalcone 4'-O-glucoside + UDP
Eriodictyol chalcone + UDP-glucose <=> 2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + UDP
2',4,4',6'-Tetrahydroxychalcone 4'-O-glucoside + Oxygen <=> Aureusidin 6-O-glucoside + H2O
2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + Oxygen <=> Bracteatin 6-O-glucoside + H2O
2 2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + Oxygen <=> 2 Aureusidin 6-O-glucoside + 2 H2O
Aureusidin <=> Bracteatin
Eriodictyol <=> Homoeriodictyol
Naringenin chalcone + UDP-glucose <=> Phlorizin chalcone + UDP
Trinitrotoluene + 2 NADPH + 2 H+ <=> 4-Hydroxylamino-2,6-dinitrotoluene + 2 NADP+ + H2O
4-Hydroxylamino-2,6-dinitrotoluene + 2 NADPH + 2 H+ <=> 2,4-Dihydroxylamino-6-nitrotoluene + 2 NADP+ + H2O
2,4-Dihydroxylamino-6-nitrotoluene + NADPH + H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + NADP+ + H2O
Trinitrotoluene + 2 NADH + 2 H+ <=> 4-Hydroxylamino-2,6-dinitrotoluene + 2 NAD+ + H2O
4-Hydroxylamino-2,6-dinitrotoluene + NADH + H+ <=> 4-Amino-2,6-dinitrotoluene + NAD+ + H2O
4-Hydroxylamino-2,6-dinitrotoluene + NADPH + H+ <=> 4-Amino-2,6-dinitrotoluene + NADP+ + H2O
4 4-Hydroxylamino-2,6-dinitrotoluene + Oxygen <=> 2 2,2',6,6'-Tetranitro-4,4'-azoxytoluene + 4 H2O
UDP-glucose + Hesperetin <=> UDP + Hesperetin 7-O-glucoside
Hesperetin 7-O-glucoside + UDP-L-rhamnose <=> Neohesperidin + UDP
4-Coumarate <=> Naringin chalcone
Naringin chalcone <=> Naringin
Naringenin <=> Hesperetin
2,4-Diamino-6-nitrotoluene <=> 2,4,6-Triaminotoluene
Pinobanksin <=> Pinobanksin 3-O-acetate
Pinocembrin <=> Pinostrobin
2,6-Diamino-4-nitrotoluene <=> 2,4,6-Triaminotoluene
Eriodictyol chalcone <=> Homoeriodictyol chalcone
Garbanzol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Fustin + [Oxidized NADPH---hemoprotein reductase] + H2O
2-Amino-4,6-dinitrotoluene <=> 2-Amino-4-nitrotoluene
2,4-Diamino-6-nitrotoluene <=> 2,4-Diamino-6-hydroxylaminotoluene
2,4-Diamino-6-hydroxylaminotoluene <=> 2,4,6-Triaminotoluene
2,4-Diamino-6-nitrotoluene + Acetyl-CoA <=> 4-Acetamido-2-amino-6-nitrotoluene + CoA
2 4-Hydroxylamino-2,6-dinitrotoluene + 2 2-Hydroxylamino-4,6-dinitrotoluene + Oxygen <=> 2 2,4',6,6'-Tetranitro-2',4-azoxytoluene + 4 H2O
4 2-Hydroxylamino-4,6-dinitrotoluene + Oxygen <=> 2 4,4',6,6'-Tetranitro-2,2'-azoxytoluene + 4 H2O
2,4,6-Triaminotoluene <=> 2,4,6-Trihydroxytoluene
2,4,6-Trihydroxytoluene <=> 4-Cresol
Trinitrotoluene + 2 NADH + 2 H+ <=> 2-Hydroxylamino-4,6-dinitrotoluene + 2 NAD+ + H2O
2-Hydroxylamino-4,6-dinitrotoluene + NADH + H+ <=> 2-Amino-4,6-dinitrotoluene + NAD+ + H2O
2-Amino-4,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,6-Diamino-4-nitrotoluene + 3 NAD+ + 2 H2O
2-Amino-4,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diamino-6-nitrotoluene + 3 NAD+ + 2 H2O
4-Amino-2,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diamino-6-nitrotoluene + 3 NAD+ + 2 H2O
4-Amino-2,6-dinitrotoluene + 2 NADH + 2 H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + 2 NAD+ + H2O
2,4-Dihydroxylamino-6-nitrotoluene <=> 2-Amino-5-hydroxyl-4-hydroxylamino-6-nitrotoluene
4-Amino-2-hydroxylamino-6-nitrotoluene <=> 2,4-Diamino-6-nitrotoluene
Ectoine + 2-Oxoglutarate + Oxygen <=> 5-Hydroxyectoine + Succinate + CO2
Dimethylallyl diphosphate + ATP <=> Isopentenyladenosine-5'-triphosphate + Diphosphate
Dimethylallyl diphosphate + ADP <=> Isopentenyladenosine-5'-diphosphate + Diphosphate
Isopentenyladenosine-5'-triphosphate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> trans-Zeatin riboside triphosphate + [Oxidized NADPH---hemoprotein reductase] + H2O
Isopentenyladenosine-5'-diphosphate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> trans-Zeatin riboside diphosphate + [Oxidized NADPH---hemoprotein reductase] + H2O
N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> trans-Zeatin riboside monophosphate + [Oxidized NADPH---hemoprotein reductase] + H2O
D-Glucarate <=> 2-Dehydro-3-deoxy-D-glucarate + H2O
2 GTP <=> 3',5'-Cyclic diGMP + 2 Diphosphate
5,6,7,8-Tetrahydromethanopterin + Formaldehyde <=> 5,10-Methylenetetrahydromethanopterin + H2O
5,10-Methylenetetrahydromethanopterin + NADP+ <=> 5,10-Methenyltetrahydromethanopterin + NADPH
Formylmethanofuran + H2O <=> Formate + Methanofuran
Isopentenyladenosine-5'-triphosphate + H2O <=> Isopentenyladenosine-5'-diphosphate + Orthophosphate
Isopentenyladenosine-5'-diphosphate + H2O <=> N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + Orthophosphate
trans-Zeatin riboside triphosphate + H2O <=> trans-Zeatin riboside diphosphate + Orthophosphate
trans-Zeatin riboside diphosphate + H2O <=> trans-Zeatin riboside monophosphate + Orthophosphate
trans-Zeatin riboside monophosphate <=> Dihydrozeatin riboside monophosphate
Isopentenyl adenosine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> trans-Zeatin riboside + [Oxidized NADPH---hemoprotein reductase] + H2O
trans-Zeatin riboside <=> Dihydrozeatin riboside
N6-(Delta2-Isopentenyl)-adenine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Zeatin + [Oxidized NADPH---hemoprotein reductase] + H2O
N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + H2O <=> Isopentenyl adenosine + Orthophosphate
trans-Zeatin riboside monophosphate + H2O <=> trans-Zeatin riboside + Orthophosphate
Dihydrozeatin riboside monophosphate + H2O <=> Dihydrozeatin riboside + Orthophosphate
Isopentenyl adenosine + H2O <=> N6-(Delta2-Isopentenyl)-adenine + D-Ribose
trans-Zeatin riboside + H2O <=> Zeatin + D-Ribose
Dihydrozeatin riboside + H2O <=> Dihydrozeatin + D-Ribose
Zeatin + UDP-glucose <=> trans-Zeatin-7-beta-D-glucoside + UDP
Dihydrozeatin + UDP-glucose <=> Dihydrozeatin-O-glucoside + UDP
tRNA containing 6-isopentenyladenosine <=> cis-Prenyl-tRNA
cis-Prenyl-tRNA <=> cis-Zeatin riboside monophosphate
cis-Zeatin riboside monophosphate + H2O <=> cis-Zeatin riboside + Orthophosphate
cis-Zeatin riboside + H2O <=> cis-Zeatin + D-Ribose
Pinocembrin + 2-Oxoglutarate + Oxygen <=> Chrysin + Succinate + CO2 + H2O
Pinobanksin + 2-Oxoglutarate + Oxygen <=> Galangin + Succinate + CO2 + H2O
Nerol + NADP+ <=> cis-Citral + NADPH + H+
beta-Citronellol + NADP+ <=> (R)-(+)-Citronellal + NADPH + H+
(-)-Citronellol + NADP+ <=> (S)-(-)-Citronellal + NADPH + H+
Geranial + NAD+ + H2O <=> Geranic acid + NADH + H+
(R)-(+)-Citronellal + NAD+ + H2O <=> Citronellate + NADH + H+
Citronellate + CoA + ATP <=> Citronellyl-CoA + AMP + Diphosphate
Citronellyl-CoA + Acceptor <=> Geranoyl-CoA + Reduced acceptor
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 7-Methyl-3-oxo-6-octenoyl-CoA + Acetate
7-Methyl-3-oxo-6-octenoyl-CoA + CoA <=> 5-Methylhex-4-enoyl-CoA + Acetyl-CoA
5-Methylhex-4-enoyl-CoA + FAD <=> (2E)-5-Methylhexa-2,4-dienoyl-CoA + FADH2
(2E)-5-Methylhexa-2,4-dienoyl-CoA + H2O <=> 3-Hydroxy-5-methylhex-4-enoyl-CoA
3-Hydroxy-5-methylhex-4-enoyl-CoA + NAD+ <=> 5-Methyl-3-oxo-4-hexenoyl-CoA + NADH + H+
5-Methyl-3-oxo-4-hexenoyl-CoA + CoA <=> 3-Methylcrotonyl-CoA + Acetyl-CoA
(S)-(-)-Citronellal + NAD+ + H2O <=> Citronellate + NADH + H+
Geranic acid + CoA <=> trans-Geranyl-CoA + H2O
trans-Geranyl-CoA <=> Geranoyl-CoA
cis-Citral <=> Geranial
2-Fluorobenzoate + NADH + H+ + Oxygen <=> 2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
2-Fluorobenzoate + NADH + H+ + Oxygen <=> 6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
Astaxanthin <=> Astaxanthin diester
Fluorobenzene + NADH + Oxygen + H+ <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+
Fluorobenzene + NADH + H+ + Oxygen <=> 1-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+
4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+ <=> 4-Fluorocatechol + NADH + H+
1-Fluorocyclohexadiene-cis,cis-1,2-diol <=> Catechol + Hydrofluoric acid
Phosphatidylethanolamine + G00149 <=> 1,2-Diacyl-sn-glycerol + G13044
3-Fluorobenzoate + NADH + Oxygen + H+ <=> 3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
3-Fluorobenzoate + NADH + H+ + Oxygen <=> 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
4-Fluorobenzoate + NADH + H+ + Oxygen <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 3-Fluorocatechol + NADH + CO2 + H+
5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+
4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+
3-Fluorocatechol + Oxygen <=> 2-Fluoro-cis,cis-muconate
4-Fluorocatechol + Oxygen <=> 3-Fluoro-cis,cis-muconate
3-Fluoro-cis,cis-muconate <=> 4-Fluoromuconolactone
4-Fluorobenzoate + CoA + ATP <=> 4-Fluorobenzoyl-CoA + AMP + Diphosphate
4-Fluorobenzoyl-CoA + H2O <=> 4-Hydroxybenzoyl-CoA + Hydrofluoric acid
2-Fluoro-cis,cis-muconate <=> 5-Fluoromuconolactone
5-Fluoromuconolactone + H2O <=> 2-Maleylacetate + Hydrofluoric acid
4-Fluoromuconolactone + H2O <=> 2-Maleylacetate + Hydrofluoric acid
2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate <=> Catechol
6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate <=> 3-Fluorocatechol
Fructoselysine + ATP <=> Fructoselysine 6-phosphate + ADP
Fructoselysine 6-phosphate + H2O <=> L-Lysine + D-Glucose 6-phosphate
Isovitexin <=> Isovitexin 2''-O-arabinoside
Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + H2O <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + D-Glucuronate
Kaempferol-3-O-galactoside + UDP-glucose <=> Kaempferol 3-O-beta-D-glucosylgalactoside + UDP
Naringenin <=> 8-C-Glucosylnaringenin
8-C-Glucosylnaringenin <=> Vitexin
7-Dehydrocholesterol <=> 14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione
2,22,25-Trideoxyecdysone <=> 2,22-Dideoxyecdysone
2,22-Dideoxyecdysone <=> 2-Deoxyecdysone
2-Deoxyecdysone <=> Ecdysone
14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione <=> 2,22-Dideoxy-3-dehydroecdysone
14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione <=> 2,22,25-Trideoxyecdysone
2,22-Dideoxy-3-dehydroecdysone <=> 3-Dehydro-2-deoxyecdysone
3-Dehydro-2-deoxyecdysone <=> 3-Dehydroecdysone
3-Dehydroecdysone + NADH + H+ <=> 3-Epiecdysone + NAD+
3-Dehydroecdysone + NADH + H+ <=> Ecdysone + NAD+
Ecdysone <=> 26-Hydroxyecdysone
20-Hydroxyecdysone <=> 20,26-Dihydroxyecdysone
trans,trans-Farnesyl diphosphate + 2 H2O <=> (2E,6E)-Farnesol + 2 Orthophosphate
Farnesol <=> Farnesal
2-trans,6-trans-Farnesal + NAD+ + H2O <=> Farnesoic acid + NADH + H+
Farnesoic acid + S-Adenosyl-L-methionine <=> Methyl farnesoate + S-Adenosyl-L-homocysteine
Methyl farnesoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Juvenile hormone III + [Oxidized NADPH---hemoprotein reductase] + H2O
Juvenile hormone III + H2O <=> Juvenile hormone III acid + Methanol
(10S)-Juvenile hormone III diol + H2O <=> (10S)-Juvenile hormone III acid diol + Methanol
Juvenile hormone III acid + S-Adenosyl-L-methionine <=> Juvenile hormone III + S-Adenosyl-L-homocysteine
Juvenile hormone III acid + H2O <=> (10S)-Juvenile hormone III acid diol
Juvenile hormone III + H2O <=> (10S)-Juvenile hormone III diol
(10S)-Juvenile hormone III diol + ATP <=> (10S)-Juvenile hormone III diol phosphate + ADP
Juvenile hormone III <=> 12-trans-Hydroxy juvenile hormone III
Octanoyl-[acp] + H2O <=> Acyl-carrier protein + Octanoic acid
Decanoyl-[acp] + H2O <=> Acyl-carrier protein + Decanoic acid
Tetradecanoyl-[acp] + H2O <=> Acyl-carrier protein + Tetradecanoic acid
L-Tryptophan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Indole-3-acetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Hexadecanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Hexadecenoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O
Hexadecenoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + (9Z)-Hexadecenoic acid
Octadecanoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Octadecanoic acid
Indolylmethylthiohydroximate + UDP-glucose <=> Indolylmethyl-desulfoglucosinolate + UDP
Isochorismate + 2-Oxoglutarate <=> 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO2
2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate <=> (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + Pyruvate
Indolylmethyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucobrassicin + Adenosine 3',5'-bisphosphate
Indole-3-acetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O <=> Indolylmethylthiohydroximate + Pyruvate + Ammonia
3'-N-Debenzoyltaxol + Benzoyl-CoA <=> Paclitaxel + CoA
Baccatin III + beta-Phenylalanoyl-CoA <=> 3'-N-Debenzoyl-2'-deoxytaxol + CoA
3'-N-Debenzoyl-2'-deoxytaxol + Reduced acceptor + Oxygen <=> 3'-N-Debenzoyltaxol + Acceptor + H2O
Stearoyl-CoA + H2O <=> CoA + Octadecanoic acid
Eicosanoyl-CoA + H2O <=> CoA + Icosanoic acid
Oleoyl-CoA + H2O <=> CoA + (9Z)-Octadecenoic acid
Linoleoyl-CoA + H2O <=> CoA + Linoleate
(9Z,12Z,15Z)-Octadecatrienoyl-CoA + H2O <=> CoA + (9Z,12Z,15Z)-Octadecatrienoic acid
(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoyl-CoA + H2O <=> CoA + (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + H2O <=> CoA + (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid
gamma-Linolenoyl-CoA + H2O <=> CoA + (6Z,9Z,12Z)-Octadecatrienoic acid
8,11,14-Eicosatrienoyl-CoA + H2O <=> CoA + Dihomo-gamma-linolenate
Arachidonyl-CoA + H2O <=> CoA + Arachidonate
Docosanoyl-CoA + H2O <=> CoA + Docosanoic acid
Tetracosanoyl-CoA + H2O <=> CoA + Tetracosanoic acid
Icosenoyl-CoA + H2O <=> CoA + Icosenoic acid
Docosenoyl-CoA + H2O <=> CoA + Erucic acid
Tetracosenoyl-CoA + H2O <=> CoA + (15Z)-Tetracosenoic acid
(7Z,10Z,13Z,16Z,19Z)-Docosapentaenoyl-CoA + H2O <=> CoA + (7Z,10Z,13Z,16Z,19Z)-Docosapentaenoic acid
(11Z,14Z)-Icosadienoyl-CoA + H2O <=> CoA + Icosadienoic acid
(7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + H2O <=> CoA + Adrenic acid
(11Z,14Z,17Z)-Icosatrienoyl-CoA + H2O <=> CoA + Icosatrienoic acid
N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetyl-alpha-D-glucosamine 1-phosphate
1,5-Anhydro-D-mannitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+
D-Threonine <=> Glycine + Acetaldehyde
D-Allothreonine <=> Glycine + Acetaldehyde
L-Arginine + Pyruvate <=> 5-Guanidino-2-oxopentanoate + L-Alanine
2-Hydroxyglutarate + NAD+ <=> 2-Oxoglutarate + NADH + H+
Dimethylallyl diphosphate <=> Isoprene + Diphosphate
3-Phosphonopyruvate + H2O <=> Pyruvate + Orthophosphate
ATP + 2-Oxoglutarate + HCO3- <=> ADP + Orthophosphate + Oxalosuccinate
Chlorophyllide + Oxygen + NADPH + H+ <=> 7(1)-Hydroxychlorophyllide a + H2O + NADP+
7(1)-Hydroxychlorophyllide a + Oxygen + NADPH + H+ <=> Chlorophyllide b + 2 H2O + NADP+
Androstenedione + NADPH + H+ + Oxygen <=> Testololactone + NADP+ + H2O
17alpha-Hydroxyprogesterone + NADPH + H+ + Oxygen <=> Androstenedione + Acetate + NADP+ + H2O
Marmesin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Psoralen + [Oxidized NADPH---hemoprotein reductase] + Acetone + 2 H2O
Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H+
Dimethylallyl diphosphate + 2 Oxidized ferredoxin + H2O <=> 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + 2 Reduced ferredoxin + 2 H+
Betaine aldehyde + Oxygen + H2O <=> Betaine + Hydrogen peroxide
Choline + 2 Oxygen + H2O <=> Betaine + 2 Hydrogen peroxide
2-Oxoglutarate + Acetyl-CoA <=> trans-Homoaconitate + CoA
(-)-threo-Iso(homo)2-citrate + NAD+ <=> 2-Oxopimelate + CO2 + NADH + H+
(-)-threo-Iso(homo)3-citrate + NAD+ <=> 2-Oxosuberate + CO2 + NADH + H+
7-Mercaptoheptanoylthreonine + ATP <=> Coenzyme B + ADP
ATP + L-Serine + tRNA(Sec) <=> AMP + Diphosphate + L-Seryl-tRNA(Sec)
L-Seryl-tRNA(Sec) + Selenophosphoric acid <=> L-Selenocysteinyl-tRNA(Sec) + Orthophosphate
Capecitabine + H2O <=> 5'-Deoxy-5-fluorocytidine + 1-Pentanol + CO2
5'-Deoxy-5-fluorocytidine + H2O <=> 5'-Deoxy-5-fluorouridine + Ammonia
5'-Deoxy-5-fluorouridine + Orthophosphate <=> 5-FU + 5-Deoxyribose-1-phosphate
L-Seryl-tRNA(Sec) + ATP <=> O-Phosphoseryl-tRNA(Sec) + ADP
O-Phosphoseryl-tRNA(Sec) + Selenophosphoric acid + H2O <=> L-Selenocysteinyl-tRNA(Sec) + 2 Orthophosphate
Tegafur + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-FU + Succinic aldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O
5-FU + NADPH + H+ <=> 5,6-Dihydro-5-fluorouracil + NADP+
5,6-Dihydro-5-fluorouracil + H2O <=> alpha-Fluoro-beta-ureidopropionic acid
alpha-Fluoro-beta-ureidopropionic acid + H2O <=> alpha-Fluoro-beta-alanine + CO2 + Ammonia
5-FU + alpha-D-Ribose 1-phosphate <=> 5-Fluorouridine + Orthophosphate
5-FU + 2-Deoxy-D-ribose 1-phosphate <=> 5-Fluorodeoxyuridine + Orthophosphate
5-FU + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 5-Fluorouridine monophosphate + Diphosphate
5-Fluorouridine + ATP <=> 5-Fluorouridine monophosphate + ADP
5-Fluorodeoxyuridine + ATP <=> 5-Fluorodeoxyuridine monophosphate + ADP
Azathioprine <=> 6-Mercaptopurine + 1-Methyl-4-nitroimidazole
6-Mercaptopurine + 2 H2O + 2 Oxygen <=> 6-Thiourate + 2 Hydrogen peroxide
6-Mercaptopurine + S-Adenosyl-L-methionine <=> 6-Methylmercaptopurine + S-Adenosyl-L-homocysteine
6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate
6-Methylmercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + Diphosphate
6-Thioinosine-5'-monophosphate + S-Adenosyl-L-methionine <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + S-Adenosyl-L-homocysteine
6-Thioinosine-5'-monophosphate + NAD+ + H2O <=> 6-Thioxanthine 5'-monophosphate + NADH + H+
6-Thioinosine-5'-monophosphate + ATP <=> 6-Mercaptopurine ribonucleoside 5'-diphosphate + ADP
6-Mercaptopurine ribonucleoside 5'-diphosphate + ATP <=> 6-Mercaptopurine ribonucleoside triphosphate + ADP
6-Mercaptopurine ribonucleoside triphosphate + H2O <=> 6-Thioinosine-5'-monophosphate + Diphosphate
6-Thioxanthine 5'-monophosphate + ATP + L-Glutamine + H2O <=> 6-Thioguanosine monophosphate + AMP + Diphosphate + L-Glutamate
Thioguanine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioguanosine monophosphate + Diphosphate
6-Thioguanosine monophosphate + S-Adenosyl-L-methionine <=> 6-Methylthioguanosine monophosphate + S-Adenosyl-L-homocysteine
beta-D-Ribopyranose <=> beta-D-Ribofuranose
Acetyl-CoA + Isoniazid <=> CoA + N-Acetylisoniazid
N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid
Acetyl-CoA + Acetylhydrazine <=> CoA + N,N'-Diacetylhydrazine
Isoniazid + H2O <=> Isonicotinic acid + Hydrazine
Isonicotinic acid + Glycine <=> Isonicotinylglycine
Isoniazid + Pyruvate <=> Isoniazid pyruvate + H2O
Isoniazid + 2-Oxoglutarate <=> Isoniazid alpha-ketoglutaric acid + H2O
Irinotecan + H2O <=> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid
Irinotecan <=> APC
Irinotecan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> NPC + Glutaral + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
NPC + H2O <=> SN-38 + 4-Amino-1-piperidinecarboxylic acid
SN-38 + UDP-glucuronate <=> SN38 glucuronide + UDP
SN38 glucuronide + H2O <=> SN-38 + D-Glucuronate
UDP-glucuronate + Codeine <=> UDP + Codeine-6-glucuronide
Morphine + UDP-glucuronate <=> Morphine-3-glucuronide + UDP
Morphine + UDP-glucuronate <=> Morphine-6-glucuronide + UDP
Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Norcodeine + Formaldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O
Morphine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Normorphine + Formaldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O
Tamoxifen + Oxygen + NADPH + H+ <=> Tamoxifen N-oxide + NADP+ + H2O
Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O
Tamoxifen <=> N-Desmethyltamoxifen
Hydroxytamoxifen <=> Endoxifen
N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O
Tamoxifen + NADPH + Oxygen + H+ <=> alpha-Hydroxytamoxifen + NADP+ + H2O
N-Desmethyltamoxifen <=> N,N-Didesmethyltamoxifen
(13Z,16Z)-Docosadienoyl-CoA + H2O <=> CoA + (13Z,16Z)-Docosadienoic acid
N-Desmethyltamoxifen + NADPH + H+ + Oxygen <=> alpha-Hydroxy-N-desmethyltamoxifen + H2O + NADP+
Cyclophosphamide + NADPH + H+ + Oxygen <=> 4-Hydroxycyclophosphamide + NADP+ + H2O
Cyclophosphamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
4-Hydroxycyclophosphamide <=> 4-Ketocyclophosphamide
4-Hydroxycyclophosphamide <=> Aldophosphamide
Aldophosphamide <=> Phosphoramide mustard + Acrolein
Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O
Aldophosphamide + NADH + H+ <=> Alcophosphamide + NAD+
Aldophosphamide + NAD+ + H2O <=> Carboxyphosphamide + NADH + H+
Aldophosphamide + NADP+ + H2O <=> Carboxyphosphamide + NADPH + H+
Carboxyphosphamide <=> Nornitrogen mustard
Ifosfamide + NADPH + H+ + Oxygen <=> 4-Hydroxyifosfamide + NADP+ + H2O
Ifosfamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
Ifosfamide <=> 2-Dechloroethylifosfamide + Chloroacetaldehyde
4-Hydroxyifosfamide <=> Aldoifosfamide
Aldoifosfamide <=> Isophosphoramide mustard + Acrolein
Aldoifosfamide <=> Alcoifosfamide
4-Hydroxyifosfamide <=> 4-Ketoifosfamide
Aldoifosfamide <=> Carboxyifosfamide
Lidocaine <=> Monoethylglycinexylidide
Lidocaine + NADPH + Oxygen + H+ <=> 3-Hydroxylidocaine + NADP+ + H2O
Monoethylglycinexylidide + H2O <=> 2,6-Dimethylaniline + N-Ethylglycine
Monoethylglycinexylidide <=> Glycinexylidide
3-Hydroxylidocaine <=> 3-Hydroxymonoethylglycinexylidide
Monoethylglycinexylidide <=> 3-Hydroxymonoethylglycinexylidide
Glycinexylidide <=> 2,6-Dimethylaniline
Lidocaine + H2O <=> 2,6-Dimethylaniline + N,N-Diethylglycine
2,6-Dimethylaniline <=> 4-Hydroxy-2,6-dimethylaniline
2,6-Dimethylaniline <=> 2-Amino-3-methylbenzoate
Felbamate + NADPH + H+ + Oxygen <=> p-Hydroxyfelbamate + NADP+ + H2O
Felbamate + NADPH + H+ + Oxygen <=> 2-Hydroxyfelbamate + NADP+ + H2O
Felbamate + H2O <=> 2-Phenyl-1,3-propanediol monocarbamate + CO2 + Ammonia
2-Phenyl-1,3-propanediol monocarbamate + NAD+ <=> 3-Carbamoyl-2-phenylpropionaldehyde + NADH + H+
3-Carbamoyl-2-phenylpropionaldehyde + NAD+ + H2O <=> 3-Carbamoyl-2-phenylpropionic acid + NADH + H+
3-Carbamoyl-2-phenylpropionaldehyde <=> Atropaldehyde + CO2 + Ammonia
3-Carbamoyl-2-phenylpropionaldehyde <=> 4-Hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one
4-Hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one + NAD+ <=> 5-Phenyl-1,3-oxazinane-2,4-dione + NADH + H+
5-Phenyl-1,3-oxazinane-2,4-dione + H2O <=> 3-Carbamoyl-2-phenylpropionic acid
Carbamazepine + NADPH + H+ + Oxygen <=> Carbamazepine-10,11-epoxide + NADP+ + H2O
Carbamazepine + NADPH + H+ + Oxygen <=> 3-Hydroxycarbamazepine + NADP+ + H2O
Carbamazepine-10,11-epoxide + H2O <=> Dihydroxycarbazepine
3-Hydroxycarbamazepine <=> 2,3-Dihydroxycarbamazepine
2,3-Dihydroxycarbamazepine <=> Carbamazepine-o-quinone
Carbamazepine <=> 2-Hydroxycarbamazepine
2-Hydroxycarbamazepine <=> 2-Hydroxyiminostilbene
2-Hydroxyiminostilbene <=> 2H-Dibenz[b,f]azepin-2-one
2-Hydroxycarbamazepine <=> 2,3-Dihydroxycarbamazepine
Oxcarbazepine <=> 10-Hydroxycarbazepine
10-Hydroxycarbazepine <=> Dihydroxycarbazepine
7-Mercaptoheptanoic acid + L-Threonine + ATP <=> 7-Mercaptoheptanoylthreonine + ADP + Orthophosphate
Valproic acid <=> 2-n-Propyl-4-pentenoic acid
Valproic acid + NADPH + H+ + Oxygen <=> 4-Hydroxyvalproic acid + NADP+ + H2O
Valproic acid + NADPH + H+ + Oxygen <=> 5-Hydroxyvalproic acid + NADP+ + H2O
Valproic acid + NADPH + H+ + Oxygen <=> 3-Hydroxyvalproic acid + NADP+ + H2O
2-Oxosuberate <=> 7-Oxoheptanoic acid + CO2
2-n-Propyl-4-pentenoic acid <=> 2-Propyl-2,4-pentadienoic acid
4-Hydroxyvalproic acid <=> 2-n-Propyl-4-oxopentanoic acid
2-Oxoadipate + Acetyl-CoA + H2O <=> (R)-(Homo)2-citrate + CoA
2-Oxopimelate + Acetyl-CoA + H2O <=> (R)-(Homo)3-citrate + CoA
2-n-Propyl-4-oxopentanoic acid <=> 2-Propylsuccinic acid
5-Hydroxyvalproic acid <=> 2-Propylglutaric acid
3-Hydroxyvalproic acid <=> 3-Oxovalproic acid
Valproic acid <=> 2-n-Propyl-2-pentenoic acid
Valproic acid <=> 2-n-Propyl-3-pentenoic acid
2-n-Propyl-2-pentenoic acid <=> 3-Hydroxyvalproic acid
Methadone <=> 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine <=> 2-Ethyl-5-methyl-3,3-diphenyl-1-pyrroline
Levomethadyl acetate <=> L-alpha-Acetyl-N-normethadol
L-alpha-Acetyl-N-normethadol <=> L-alpha-Acetyl-N,N-dinormethadol
Citalopram <=> Demethylcitalopram
Citalopram <=> Citalopram N-oxide
Demethylcitalopram <=> Didemethylcitalopram
Citalopram + Oxygen + H2O <=> Citalopram aldehyde + Dimethylamine + Hydrogen peroxide
Demethylcitalopram + Oxygen + H2O <=> Citalopram aldehyde + Methylamine + Hydrogen peroxide
Didemethylcitalopram + H2O + Oxygen <=> Citalopram aldehyde + Ammonia + Hydrogen peroxide
Citalopram aldehyde + H2O + Oxygen <=> Citalopram propionic acid + Hydrogen peroxide
Trypanothione + H2O <=> Glutathione + Glutathionylspermidine
Homotrypanothione + H2O <=> Glutathione + Glutathionylaminopropylcadaverine
ATP + Glutathione + Spermine <=> ADP + Orthophosphate + Glutathionylspermine
ATP + Glutathione + Glutathionylspermine <=> ADP + Orthophosphate + Bis(glutathionyl)spermine
ATP + Glutathione + Aminopropylcadaverine <=> ADP + Orthophosphate + Glutathionylaminopropylcadaverine
ATP + Glutathione + Glutathionylaminopropylcadaverine <=> ADP + Orthophosphate + Homotrypanothione
Bis(glutathionyl)spermine + NADP+ <=> Bis(glutathionyl)spermine disulfide + NADPH + H+
Homotrypanothione + NADP+ <=> Homotrypanothione disulfide + NADPH + H+
Trypanothione + Dehydroascorbate <=> Trypanothione disulfide + Ascorbate
S-Adenosylmethioninamine + Cadaverine <=> 5'-Methylthioadenosine + Aminopropylcadaverine
Tryparedoxin + ROOH <=> Tryparedoxin disulfide + H2O + ROH
Trypanothione + Tryparedoxin disulfide <=> Trypanothione disulfide + Tryparedoxin
Trypanothione + ROOH <=> Trypanothione disulfide + H2O + ROH
2'-Deoxyribonucleoside diphosphate + Tryparedoxin disulfide + H2O <=> Ribonucleoside diphosphate + Tryparedoxin
2'-Deoxyribonucleoside diphosphate + Trypanothione disulfide + H2O <=> Ribonucleoside diphosphate + Trypanothione
D-Galactosamine 6-phosphate + H2O <=> D-Tagatose 6-phosphate + Ammonia
N-Acetyl-D-galactosamine + Protein N(pi)-phospho-L-histidine <=> N-Acetyl-D-galactosamine 6-phosphate + Protein histidine
D-Galactosamine + Protein N(pi)-phospho-L-histidine <=> D-Galactosamine 6-phosphate + Protein histidine
N-D-Ribosylpurine + Orthophosphate <=> Purine + alpha-D-Ribose 1-phosphate
UDP-glucose + N6-Alkylaminopurine <=> UDP + N6-Alkylaminopurine-9-beta-D-glucoside
trans,trans-Farnesyl diphosphate <=> (E)-alpha-Bisabolene + Diphosphate
2 delta-Cadinene <=> Gossypol
1-Hydroxyalkyl-sn-glycerol <=> Aldehyde + Glycerol
trans,trans-Farnesyl diphosphate <=> Humulene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Nerolidol + Diphosphate
(S)-2,3-Epoxysqualene <=> Euphol
Euphol <=> Azadirachtin A
(S)-2,3-Epoxysqualene <=> Cucurbitacin E
Retinol + NADP+ <=> Retinal + NADPH + H+
11-cis-Retinol + NADP+ <=> 11-cis-Retinal + NADPH + H+
Palmitoyl-CoA + 11-cis-Retinol <=> CoA + 11-cis-Retinyl palmitate
9-cis-Retinol + NAD+ <=> 9-cis-Retinal + NADH + H+
9-cis-Retinol + NADP+ <=> 9-cis-Retinal + NADPH + H+
9-cis-Retinal + Oxygen + H2O <=> 9-cis-Retinoic acid + Hydrogen peroxide
9-cis-Retinal + NAD+ + H2O <=> 9-cis-Retinoic acid + NADH + H+
Acetyl-CoA + N-Hydroxyarylamine <=> CoA + N-Acetoxyarylamine
Phosphatidylcholine + Retinol <=> 2-Acyl-sn-glycero-3-phosphocholine + Retinyl ester
Retinyl ester + H2O <=> 11-cis-Retinol + Fatty acid
Palmitoylphosphatidylcholine + 11-cis-Retinol <=> 11-cis-Retinyl palmitate + 2-Acyl-sn-glycero-3-phosphocholine
Retinoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> all-trans-18-Hydroxyretinoic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Retinoate + NADPH + H+ + Oxygen <=> all-trans-5,6-Epoxyretinoic acid + NADP+ + H2O
Retinoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> all-trans-4-Hydroxyretinoic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Geranyl diphosphate <=> Nerol
Geranyl diphosphate <=> cis-Citral
Geranyl diphosphate <=> Car-3-ene + Diphosphate
Geranyl diphosphate + H2O <=> Geraniol + Diphosphate
Geranyl diphosphate <=> beta-Citronellol
Geranyl diphosphate <=> Geranial
Geranyl diphosphate <=> (R)-(+)-Citronellal
poly-cis-Polyprenyl diphosphate + Isopentenyl diphosphate <=> poly-cis-Polyprenyl diphosphate longer by one C5 unit + Diphosphate
ent-Kaurene <=> Stevioside
Copalyl diphosphate <=> Ginkgolide A
DNA 2,6-diamino-5-formamido-3,4-dihydro-4-oxopyrimidine <=> DNA containing guanine + H2O
Acyl phosphate + D-Glucose <=> Carboxylate + D-Glucose 6-phosphate
Acyl phosphate + D-Mannose <=> Carboxylate + D-Mannose 6-phosphate
Acyl phosphate + D-Fructose <=> Carboxylate + D-Fructose 6-phosphate
Acyl phosphate + D-Fructose <=> Carboxylate + D-Fructose 1-phosphate
1-Methylnicotinamide + Oxygen + H2O <=> N1-Methyl-2-pyridone-5-carboxamide + Hydrogen peroxide + H+
Plastoquinol-9 + 2 Oxidized plastocyanin + 2 H+ <=> Plastoquinone-9 + 2 Reduced plastocyanin + 4 H+
Xanthine + 2 S-Adenosyl-L-methionine <=> Theophylline + 2 S-Adenosyl-L-homocysteine
L-Leucine <=> 3-Methylbutanoic acid
L-Histidine + 3-Methylbutanoic acid <=> Dolichotheline
L-Histidine <=> Pilocarpine
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate <=> L-Pipecolate
L-Pipecolate <=> 1-Indolizidinone
1-Indolizidinone <=> Swainsonine
1-Indolizidinone <=> Slaframine
Cadaverine <=> Lupinine
Cadaverine <=> (-)-Sparteine
(-)-Sparteine <=> Cytisine
Cadaverine <=> Lupanine
Piperideine + trans-Cinnamate <=> (-)-Sedamine
Piperideine + trans-Cinnamate + Benzoyl-CoA <=> Lobelanine + CoA
Lobelanine <=> Lobeline
N-Methylpelletierine <=> Pseudopelletierine
Nicotinate <=> 3,6-Dihydronicotinic acid
1-Methylpyrrolinium <=> Cuscohygrine
1-Methylpyrrolinium <=> (-)-Hygrine
1-Methylpyrrolinium <=> Ecgonine methyl ester
Ecgonine methyl ester + Benzoyl-CoA <=> Cocaine + CoA
1-Methylpyrrolinium <=> Tropinone
Tropine + (R)-Phenyllactyl-CoA <=> Littorine + CoA
Acetyl-CoA + Co(I) corrinoid protein + H+ <=> CO + Methyl-Co(III) corrinoid protein + CoA
Littorine <=> L-Hyoscyamine
4-Coumarate <=> 3,4-Dihydroxybenzaldehyde
Tyramine + 3,4-Dihydroxybenzaldehyde <=> Norcraugsodine + H2O
Norbelladine + S-Adenosyl-L-methionine <=> 4'-O-Methylnorbelladine + S-Adenosyl-L-homocysteine
4'-O-Methylnorbelladine <=> Noroxopluviine
(4aR,10bS)-Normaritidine <=> Crinine
4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N-Demethylnarwedine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Norgalanthamine + S-Adenosyl-L-methionine <=> Galanthamine + S-Adenosyl-L-homocysteine
N-Demethylnarwedine + NADPH <=> Norgalanthamine + NADP+
3,4-Dihydroxy-L-phenylalanine <=> (-)-Salsolinol
Dopamine <=> Mescaline
Dopamine <=> Anhalamine
Anhalonidine + S-Adenosyl-L-methionine <=> Anhalonine + S-Adenosyl-L-homocysteine
Dopamine + 4-Hydroxydihydrocinnamaldehyde <=> (S)-Autumnaline
(S)-Autumnaline + NADPH + Oxygen + H+ <=> Isoandrocymbine + NADP+ + 2 H2O
Isoandrocymbine + S-Adenosyl-L-methionine <=> O-Methylandrocymbine + S-Adenosyl-L-homocysteine
O-Methylandrocymbine <=> N-Formyldemecolcine
N-Formyldemecolcine + H2O <=> Demecolcine + Formate
Demecolcine <=> Deacetylcolchicine
Deacetylcolchicine + Acetyl-CoA <=> Colchicine + CoA
(S)-Autumnaline <=> Floramultine
Floramultine + S-Adenosyl-L-methionine <=> Kreysigine + S-Adenosyl-L-homocysteine
(S)-Coclaurine <=> (S)-6-O-Methylnorlaudanosoline
(S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine <=> Tubocurarine
2 (S)-N-Methylcoclaurine <=> (+)-Tetrandrine
(S)-Reticuline <=> (S)-Isoboldine
Limonin + H2O <=> Limonoate A-ring-lactone
L-Phenylalanine <=> D-Cathinone
D-Cathinone <=> D-Cathine
D-Cathine + S-Adenosyl-L-methionine <=> (+)-(1S,2S)-Pseudoephedrine + S-Adenosyl-L-homocysteine
D-Cathinone <=> (-)-Norephedrine
(-)-Norephedrine + S-Adenosyl-L-methionine <=> Ephedrine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + Peptide 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide 2-[3-carboxy-3-(dimethylammonio)propyl]-L-histidine
S-Adenosyl-L-methionine + Peptide 2-[3-carboxy-3-(dimethylammonio)propyl]-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide diphthine
1,3-Dihydroxy-N-methylacridone <=> Melicopicine
1,3-Dihydroxy-N-methylacridone <=> Acronycine
1,3-Dihydroxy-N-methylacridone <=> Rutacridone
Anthranilate <=> 4-Hydroxy-2-quinolone
4-Hydroxy-2-quinolone <=> Platydesmine
Platydesmine <=> Dictamnine
Dictamnine <=> Skimmianine
Anthranilate + 1-Pyrroline <=> Peganine
N-Acetylanthranilate + L-Aspartate <=> Peganine
ATP + Psilocin <=> ADP + Psilocybin
Tryptamine <=> Physostigmine
Tryptamine <=> Harman
Tryptamine <=> Calligonine
Tryptamine <=> Harmaline
Harmaline <=> Harmine
Harmaline <=> Tetrahydroharmine
3-alpha(S)-Strictosidine <=> Strictosamide
Strictosamide <=> Pumiloside
Pumiloside <=> Deoxypumiloside
Deoxypumiloside <=> Camptothecin
Corynantheal <=> Cinchoninone
Cinchoninone + NADPH + H+ <=> Cinchonine + NADP+
Quinidinone + NADPH + H+ <=> Quinidine + NADP+
3-alpha(S)-Strictosidine <=> Strychnine
3-alpha(S)-Strictosidine <=> Corynantheal
Corynantheal <=> Quinidinone
Corynantheal <=> Cinchonamine
(6E)-8-Hydroxygeraniol + 2 NADP+ <=> (6E)-8-Oxogeranial + 2 NADPH + 2 H+
Secologanin <=> Gentiopicrin
Geraniol <=> beta-Skytanthine
Geraniol <=> Actinidine
5-Deoxy-D-glucuronate <=> 2-Deoxy-5-keto-D-gluconic acid
Cholesterol + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> Cholest-5-ene-3beta,26-diol + H2O + 2 Oxidized adrenal ferredoxin
Cholest-5-ene-3beta,26-diol <=> Solasodine
Cholest-5-ene-3beta,26-diol <=> Tomatidine
Cholest-5-ene-3beta,26-diol <=> Solanidine
Octanoic acid <=> gamma-Coniceine
gamma-Coniceine + NADPH + H+ <=> Coniine + NADP+
Nitrile + Glutathione <=> Hydrogen cyanide + R-S-Glutathione
Sulfuric monoester + Glutathione <=> Sulfate + R-S-Glutathione
Dopamine <=> Anhalonidine
Phosphoramidate + D-Glucose <=> D-Glucose 1-phosphate + Ammonia
ADP + D-Glucose 1-phosphate <=> Orthophosphate + ADP-glucose
17alpha-Hydroxypregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Dehydroepiandrosterone + Acetate + [Oxidized NADPH---hemoprotein reductase] + H2O
17alpha-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Androstenedione + Acetate + [Oxidized NADPH---hemoprotein reductase] + H2O
L-Tyrosyl-tRNA(Tyr) <=> [Thyroglobulin]-L-tyrosine
[Thyroglobulin]-L-tyrosine + Iodine <=> [Thyroglobulin]-3-iodo-L-tyrosine + Hydroiodic acid
[Thyroglobulin]-3-iodo-L-tyrosine + Iodine <=> [Thyroglobulin]-3,5-diiodo-L-tyrosine + Hydroiodic acid
[Thyroglobulin]-3,5-diiodo-L-tyrosine + [Thyroglobulin]-3-iodo-L-tyrosine + Hydrogen peroxide <=> Thyroglobulin triiodothyronine + Thyroglobulin dehydroalanine + 2 H2O
2 [Thyroglobulin]-3,5-diiodo-L-tyrosine + Hydrogen peroxide <=> [Thyroglobulin]-L-thyroxine + Thyroglobulin dehydroalanine + 2 H2O
Thyroglobulin triiodothyronine <=> Triiodothyronine
[Thyroglobulin]-L-thyroxine <=> Thyroxine
Arachidonate + Oxygen <=> Leukotriene A4 + H2O
Geranyl diphosphate + Isopentenyl diphosphate <=> 2-cis,6-trans-Farnesyl diphosphate + Diphosphate
(+)-Bornyl diphosphate + H2O <=> (+)-Borneol + Diphosphate
Acetyl-CoA + (-)-Menthol <=> CoA + (-)-Menthyl acetate
Acetyl-CoA + (+)-Neomenthol <=> CoA + Neomenthyl acetate
Acetyl-CoA + (+)-Borneol <=> CoA + Bornyl acetate
UDP-glucose + Sinapate <=> UDP + 4-O-beta-D-Glucosyl-sinapate
UDP-glucose + 4-Coumarate <=> UDP + p-Coumaroyl-D-glucose
Squalene <=> Hopane-29-acetate
L-Glucitol + NAD+ <=> L-Fructose + NADH + H+
S-Adenosyl-L-methionine + N-Methylserotonin <=> S-Adenosyl-L-homocysteine + Bufotenine
S-Adenosyl-L-methionine + 5-Hydroxyxanthotoxin <=> S-Adenosyl-L-homocysteine + Isopimpinellin
NADPH + 2 Ferricytochrome b5 <=> NADP+ + 2 Ferrocytochrome b5
trans,trans-Farnesyl diphosphate <=> gamma-Humulene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Caryophyllene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Longifolene + Diphosphate
trans,trans-Farnesyl diphosphate + 2 H2O <=> Geosmin + Diphosphate + Acetone
D-Galactose + NAD+ <=> D-Galactono-1,5-lactone + NADH + H+
trans,trans-Farnesyl diphosphate <=> Germacrene B + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Selinene + Diphosphate
S-Adenosyl-L-methionine + L-Tryptophan <=> S-Adenosyl-L-homocysteine + L-2-Methyltryptophan
D-Fructose 1-phosphate + H2O <=> D-Fructose + Orthophosphate
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
[Protein]-N6-[(R)-dihydrolipoyl]-L-lysine + NAD+ <=> Protein N6-(lipoyl)lysine + NADH + H+
[Oxidized NADPH---hemoprotein reductase] + NADPH + H+ <=> [Reduced NADPH---hemoprotein reductase] + NADP+
AMP + Sulfite + FAD <=> Adenylyl sulfate + FADH2
(R)-Lactate + N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetylmuramic acid 6-phosphate + H2O
Choline + NAD+ <=> Betaine aldehyde + NADH + H+
Choline + NADP+ <=> Betaine aldehyde + NADPH + H+
N-Acetylmuramate + Protein N(pi)-phospho-L-histidine <=> N-Acetylmuramic acid 6-phosphate + Protein histidine
Cinchonidinone <=> Cinchoninone
Cinchoninone + NADPH + H+ <=> Cinchonidine + NADP+
Quinidinone + NADPH + H+ <=> Quinine + NADP+
Cinchonidinone + NADPH + H+ <=> Cinchonidine + NADP+
Corynantheal <=> Cinchonidinone
4-Methyl-2-oxopentanoate + CoA + 2 Oxidized ferredoxin <=> 3-Methylbutanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+
(S)-3-Methyl-2-oxopentanoic acid + CoA + 2 Oxidized ferredoxin <=> (S)-2-Methylbutanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+
L-Aspartate 4-semialdehyde + 6-Deoxy-5-ketofructose 1-phosphate <=> 2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + Hydroxypyruvaldehyde phosphate
2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + H2O + NAD+ <=> 3-Dehydroquinate + Ammonia + NADH + H+
2-Dehydro-3-deoxy-D-gluconate <=> D-Glyceraldehyde + Pyruvate
D-Glyceraldehyde + H2O + Oxidized ferredoxin <=> D-Glycerate + H+ + Reduced ferredoxin
D-Glycerate + ATP <=> 2-Phospho-D-glycerate + ADP
D-Threitol + NADP+ <=> D-Erythrulose + NADPH + H+
CTP + Riboflavin <=> CDP + FMN
Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Fructose 6-phosphate
O-Phospho-L-serine + tRNA(Cys) + ATP <=> O-Phosphoseryl-tRNA(Cys) + Diphosphate + AMP
O-Phosphoseryl-tRNA(Cys) + Hydrogen sulfide <=> L-Cysteinyl-tRNA(Cys) + Orthophosphate
ATP + L-Pyrrolysine + tRNA(Pyl) <=> AMP + Diphosphate + L-Pyrrolysyl-tRNA(Pyl)
Parathion <=> Paraoxon
dTDP-4-amino-4,6-dideoxy-D-glucose + S-Adenosyl-L-methionine + Reduced acceptor <=> dTDP-3-oxo-4,6-dideoxy-D-glucose + Ammonia + L-Methionine + 5'-Deoxyadenosine + Acceptor
Chlorophyll a + 2 H+ <=> Pheophytin a + Magnesium cation
Chlorophyll a <=> Chlorophyll b
Futalosine + H2O <=> Dehypoxanthine futalosine + Hypoxanthine
Dehypoxanthine futalosine + S-Adenosyl-L-methionine <=> Cyclic dehypoxanthine futalosine + 5'-Deoxyadenosine + L-Methionine
Cyclic dehypoxanthine futalosine <=> 1,4-Dihydroxy-6-naphthoate
3-Sulfopyruvate + NADH + H+ <=> 3-Sulfolactate + NAD+
dTDP-2,6-dideoxy-L-glycero-hex-2-enos-4-ulose <=> dTDP-3,4-dioxo-2,6-dideoxy-L-glucose
1,4-Dihydroxy-6-naphthoate <=> Menaquinone
dTDP-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
GDP-D-mannose + G10694 <=> GDP + G01813
N-Acetyl-4-O-acetylneuraminate + H2O <=> N-Acetylneuraminate + Acetate
N-Acetyl-9-O-acetylneuraminate + H2O <=> N-Acetylneuraminate + Acetate
S-Palmitoylprotein + H2O <=> Hexadecanoic acid + [Protein]-L-cysteine
3D-3,5/4-Trihydroxycyclohexane-1,2-dione + H2O <=> 5-Deoxy-D-glucuronate
Tryptamine + Oxygen + NADPH <=> N-Hydroxyl-tryptamine + H2O + NADP+
N-Hydroxyl-tryptamine <=> Indole-3-acetaldehyde oxime
Indole-3-acetaldehyde oxime <=> Indole-3-acetaldehyde
Indole-3-acetaldehyde oxime + NADPH + Oxygen + H+ <=> Indole-3-acetaldoxime N-oxide + NADP+ + H2O
Indole-3-acetaldoxime N-oxide + L-Cysteine <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O
Indole <=> Indole-3-acetate
5-Hydroxymethyluracil + 2-Oxoglutarate + Oxygen <=> Uracil 5-carbaldehyde + Succinate + CO2 + H2O
Uracil 5-carbaldehyde + 2-Oxoglutarate + Oxygen <=> Uracil 5-carboxylate + Succinate + CO2
1,4-beta-D-Mannan + H2O <=> 1,4-beta-D-Mannooligosaccharide + 1,4-beta-D-Mannan
beta-D-Mannoside + H2O <=> ROH + D-Mannose
1,4-beta-D-Mannooligosaccharide + H2O <=> D-Mannose + 1,4-beta-D-Mannooligosaccharide
UDP-glucuronate + H2O <=> UDP + D-Glucuronate
2 Raffinose <=> Isolychnose + Sucrose
D-Glucose 6-phosphate <=> 2-Deoxy-scyllo-inosose + Orthophosphate
L-Methionine + 2-Oxo acid <=> 4-Methylthio-2-oxobutanoic acid + L-Amino acid
4-Methylthio-2-oxobutanoic acid + Acetyl-CoA + H2O <=> 2-(2'-Methylthio)ethylmalic acid + CoA
2-(2'-Methylthio)ethylmalic acid <=> 3-(2'-Methylthio)ethylmalic acid
3-(2'-Methylthio)ethylmalic acid + NAD+ <=> 2-Oxo-5-methylthiopentanoic acid + CO2 + NADH + H+
2-Oxo-5-methylthiopentanoic acid + L-Amino acid <=> Homomethionine + 2-Oxo acid
2-Oxo-5-methylthiopentanoic acid + Acetyl-CoA + H2O <=> 2-(3'-Methylthio)propylmalic acid + CoA
2-(3'-Methylthio)propylmalic acid <=> 3-(3'-Methylthio)propylmalic acid
3-(3'-Methylthio)propylmalic acid + NAD+ <=> 2-Oxo-6-methylthiohexanoic acid + CO2 + NADH + H+
2-Oxo-6-methylthiohexanoic acid + L-Amino acid <=> Dihomomethionine + 2-Oxo acid
2-Oxo-6-methylthiohexanoic acid + Acetyl-CoA + H2O <=> 2-(4'-Methylthio)butylmalic acid + CoA
2-(4'-Methylthio)butylmalic acid <=> 3-(4'-Methylthio)butylmalic acid
3-(4'-Methylthio)butylmalic acid + NAD+ <=> 2-Oxo-7-methylthioheptanoic acid + CO2 + NADH + H+
2-Oxo-7-methylthioheptanoic acid + L-Amino acid <=> Trihomomethionine + 2-Oxo acid
2-Oxo-7-methylthioheptanoic acid + Acetyl-CoA + H2O <=> 2-(5'-Methylthio)pentylmalic acid + CoA
L-Cystathionine <=> L-Cysteine + 2-Aminobut-2-enoate
L-Homocysteine <=> Hydrogen sulfide + 2-Aminobut-2-enoate
2-(5'-Methylthio)pentylmalic acid <=> 3-(5'-Methylthio)pentylmalic acid
L-Methionine <=> Methanethiol + 2-Aminobut-2-enoate
3-(5'-Methylthio)pentylmalic acid + NAD+ <=> 2-Oxo-8-methylthiooctanoic acid + CO2 + NADH + H+
2-Aminobut-2-enoate + H2O <=> 2-Oxobutanoate + Ammonia
2-Oxo-8-methylthiooctanoic acid + L-Amino acid <=> Tetrahomomethionine + 2-Oxo acid
D-Glucose 1-phosphate <=> D-Glucose 6-phosphate
2-Oxo-8-methylthiooctanoic acid + Acetyl-CoA + H2O <=> 2-(6'-Methylthio)hexylmalic acid + CoA
2-(6'-Methylthio)hexylmalic acid <=> 3-(6'-Methylthio)hexylmalic acid
3-(6'-Methylthio)hexylmalic acid + NAD+ <=> 2-Oxo-9-methylthiononanoic acid + CO2 + NADH + H+
2-Oxo-9-methylthiononanoic acid + L-Amino acid <=> Pentahomomethionine + 2-Oxo acid
2-Oxo-9-methylthiononanoic acid + Acetyl-CoA + H2O <=> 2-(7'-Methylthio)heptylmalic acid + CoA
2-(7'-Methylthio)heptylmalic acid <=> 3-(7'-Methylthio)heptylmalic acid
3-(7'-Methylthio)heptylmalic acid + NAD+ <=> 2-Oxo-10-methylthiodecanoic acid + CO2 + NADH + H+
2-Oxo-10-methylthiodecanoic acid + L-Amino acid <=> Hexahomomethionine + 2-Oxo acid
Pyruvate + 2-Oxobutanoate <=> (S)-2-Aceto-2-hydroxybutanoate + CO2
L-Aspartate 4-semialdehyde + Glycerone phosphate <=> 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O
D-Fructose + NADP+ <=> 5-Dehydro-D-fructose + NADPH + H+
L-Phenylalanine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (Z)-Phenylacetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
(Z)-Phenylacetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
S-(Phenylacetothiohydroximoyl)-L-cysteine + H2O <=> Phenylacetothiohydroximate + Pyruvate + Ammonia
L-Homophenylalanine + 2 Oxygen + 2 NADPH + 2 H+ <=> 3-Phenylpropionaldoxim + 2 NADP+ + CO2 + 3 H2O
sn-Glycerol 3-phosphate + Ubiquinone <=> Glycerone phosphate + Ubiquinol
DL-Glycerol 1-phosphate + H2O <=> Glycerol + Orthophosphate
(Z)-4-Hydroxyphenylacetaldehyde oxime + Oxygen + NADPH + L-Cysteine + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + H2O <=> p-Hydroxyphenylacetothiohydroximate + Pyruvate + Ammonia
p-Hydroxyphenylacetothiohydroximate + UDP-glucose <=> p-Hydroxybenzyldesulphoglucosinolate + UDP
p-Hydroxybenzyldesulphoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Sinalbin + Adenosine 3',5'-bisphosphate
L-Valine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-2-Methylpropanal oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
L-Leucine + 2 Oxygen + 2 NADPH + 2 H+ <=> 3-Methylbutyraldehyde oxime + 3 H2O + 2 NADP+ + CO2
Homomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 4-Methylthiobutanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
4-Methylthiobutanaldoxime + L-Cysteine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + H2O <=> 4-Methylthiobutylthiohydroximate + Pyruvate + Ammonia
4-Methylthiobutylthiohydroximate + UDP-glucose <=> 3-Methylthiopropyl-desulfoglucosinolate + UDP
3-Methylthiopropyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucoiberverin + Adenosine 3',5'-bisphosphate
Dihomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 5-Methylthiopentanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
4-Methylthiobutyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucoerucin + Adenosine 3',5'-bisphosphate
Trihomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 6-Methylthiohexanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Tetrahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 7-Methylthioheptanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Pentahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 8-Methylthiooctanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Hexahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 9-Methylthiononanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
ADP + Sucrose <=> ADP-glucose + D-Fructose
S-Sulfanylglutathione + Oxygen + H2O <=> Glutathione + Sulfite
Amino acid + 2-Oxo acid <=> Amino acid + 2-Oxo acid
2-Oxo acid + Acetyl-CoA + H2O <=> 2-Alkylmalic acid + CoA
2-Alkylmalic acid <=> 3-Alkylmalic acid
3-Alkylmalic acid <=> Aliphatic oxo acid + CO2
Aliphatic oxo acid + Amino acid <=> Homoamino acid + 2-Oxo acid
Amino acid + 2 Oxygen + 2 NADPH + 2 H+ <=> Aldoxime + 2 NADP+ + 3 H2O + CO2
Aldoxime + NADPH + Oxygen + L-Cysteine + H+ <=> S-Alkyl-thiohydroximate + NADP+ + 2 H2O
S-Alkyl-thiohydroximate + H2O <=> Thiohydroximic acid + Pyruvate + Ammonia
Thiohydroximic acid + UDP-glucose <=> desulfo-Glucosinolate + UDP
desulfo-Glucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucosinolate + Adenosine 3',5'-bisphosphate
2-C-Methyl-D-erythritol 2,4-cyclodiphosphate + 2 Reduced ferredoxin <=> 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + H2O + 2 Oxidized ferredoxin
L-Phenylalanine <=> L-Homophenylalanine
trans,trans-Farnesyl diphosphate <=> (+)-Valencene + Diphosphate
GDP-D-mannuronate + (beta-D-Mannuronate)n <=> (beta-D-Mannuronate)n + GDP
(beta-D-Mannuronate)n <=> (Alginate)n
Pectate <=> Oligosaccharide with 4-deoxy-alpha-D-gluc-4-enuronosyl group + Pectate
trans,trans-Farnesyl diphosphate <=> beta-Farnesene + Diphosphate
trans,trans-Farnesyl diphosphate <=> alpha-Farnesene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (2E,6E)-Farnesol + Diphosphate
Dehydroalanine + H2O <=> Pyruvate + Ammonia
Dehydroalanine + 3'-Phosphoadenylyl sulfate <=> L-Cysteate + Adenosine 3',5'-bisphosphate
tRNA uridine + [Enzyme]-S-sulfanylcysteine + ATP <=> tRNA containing 2-thiouridine + [Enzyme]-cysteine + AMP + Diphosphate
tRNA containing 2-thiouridine + Glycine + Folinic acid + Reduced acceptor <=> tRNA containing 5-carboxymethylaminomethyl-2-thiouridine + Tetrahydrofolate + Acceptor + H2O
tRNA containing 5-carboxymethylaminomethyl-2-thiouridine + Oxygen + H2O <=> tRNA containing 5-(aminomethyl)-2-thiouridine + Glyoxylate + Hydrogen peroxide
UDP-4-dehydro-6-deoxy-D-glucose <=> UDP-4-keto-rhamnose
UDP-4-keto-rhamnose + NADPH + H+ <=> UDP-L-rhamnose + NADP+
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate <=> UDP-N-acetyl-D-galactosaminuronic acid
4-N-(N-Acetyl-D-glucosaminyl)-protein + H2O <=> N-Acetyl-beta-D-glucosaminylamine + Peptide L-aspartate
CDP-4-dehydro-3,6-dideoxy-D-glucose <=> CDP-4-dehydro-3,6-dideoxy-D-glucose epimer
CDP-4-dehydro-3,6-dideoxy-D-glucose epimer + NADH + H+ <=> CDP-ascarylose + NAD+
CDP-4-dehydro-3,6-dideoxy-D-glucose epimer + NADPH + H+ <=> CDP-ascarylose + NADP+
CDP-4-dehydro-3,6-dideoxy-D-glucose + NADPH + H+ <=> CDP-abequose + NADP+
Acyl-CoA + Tropine <=> CoA + O-Acyltropine
Acyl-CoA + Pseudotropine <=> CoA + O-Acylpseudotropine
Putrescine + Pyruvate <=> 4-Aminobutyraldehyde + L-Alanine
Chitosan(n+1) + H2O <=> Chitosan(n) + D-Glucosamine
Cobalt-factor III <=> Cobalt-precorrin 3
G00309 + H2O <=> G00319 + D-Mannose
G00595 + H2O <=> G00971 + D-Mannose
(24S)-Cholest-5-ene-3beta,7alpha,24-triol + NAD+ <=> 7alpha,24-Dihydroxy-4-cholesten-3-one + NADH + H+
Cholest-5-ene-3beta,7alpha,25-triol + NAD+ <=> 7alpha,25-Dihydroxy-4-cholesten-3-one + NADH + H+
7alpha,27-Dihydroxycholesterol + NAD+ <=> 7alpha,26-Dihydroxy-4-cholesten-3-one + NADH + H+
7alpha,26-Dihydroxy-4-cholesten-3-one + 2 Oxygen + 2 NADPH + 2 H+ <=> 7alpha-Hydroxy-3-oxo-4-cholestenoate + 2 NADP+ + 3 H2O
Cholest-5-ene-3beta,26-diol + 2 Oxygen + 2 NADPH + 2 H+ <=> 3beta-Hydroxy-5-cholestenoate + 2 NADP+ + 3 H2O
3beta-Hydroxy-5-cholestenoate + Oxygen + NADPH + H+ <=> 3beta,7alpha-Dihydroxy-5-cholestenoate + NADP+ + H2O
3beta,7alpha-Dihydroxy-5-cholestenoate + NAD+ <=> 7alpha-Hydroxy-3-oxo-4-cholestenoate + NADH + H+
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + ATP + CoA <=> (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + Diphosphate
(25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA <=> (25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA
(25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + Acceptor <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor
3alpha,7alpha-Dihydroxy-5beta-cholestanate + ATP + CoA <=> (25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + AMP + Diphosphate
(25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA <=> (25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
(25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + Acceptor <=> (24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor
Chenodeoxycholoyl-CoA + AMP + Diphosphate <=> Chenodeoxycholate + CoA + ATP
Chenodeoxycholoyl-CoA + Glycine <=> Glycochenodeoxycholate + CoA
Chenodeoxycholoyl-CoA + Taurine <=> Taurochenodeoxycholate + CoA
trans,trans-Farnesyl diphosphate <=> 2-cis,6-trans-Farnesyl diphosphate
all-trans-Nonaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Decaprenyl diphosphate + Diphosphate
trans,trans,cis-Geranylgeranyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Pentaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Pentaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Hexaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Heptaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Heptaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Octaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Octaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Nonaprenyl diphosphate + Diphosphate
di-trans,poly-cis-Nonaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Decaprenyl diphosphate + Diphosphate
Geranylgeranyl diphosphate + NADPH + H+ <=> Dihydrogeranylgeranyl diphosphate + NADP+
Dihydrogeranylgeranyl diphosphate + NADPH + H+ <=> Tetrahydrogeranylgeranyl diphosphate + NADP+
Tetrahydrogeranylgeranyl diphosphate + NADPH + H+ <=> Phytyl diphosphate + NADP+
Hydroxylamine + 2 Ubiquinone + H2O <=> Nitrite + 2 Ubiquinol
3alpha,7alpha,26-Trihydroxy-5beta-cholestane <=> 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al
3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al
3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha-Dihydroxy-5beta-cholestanate + H2O + 2 Oxidized adrenal ferredoxin
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + H2O + 2 Oxidized adrenal ferredoxin
2 2-Aminophenol + Oxygen <=> 2 6-Iminocyclohexa-2,4-dienone + 2 H2O
2 6-Iminocyclohexa-2,4-dienone + Acceptor <=> 2-Aminophenoxazin-3-one + Reduced acceptor
6-Hydroxynicotinate + NADH + Oxygen + H+ <=> 2,5-Dihydroxypyridine + NAD+ + CO2 + H2O
Thymine dimer <=> Two thymine residues (in DNA)
(R)-3-(4-Hydroxyphenyl)lactate <=> 4-Coumarate + H2O
p-Coumaroyl-CoA + CoA + NAD+ + H2O <=> 4-Hydroxybenzoyl-CoA + Acetyl-CoA + NADH + H+
2-Polyprenylphenol + NADPH + H+ + Oxygen <=> 2-Polyprenyl-6-hydroxyphenol + NADP+ + H2O
2-Polyprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Polyprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine
4-Hydroxy-3-polyprenylbenzoate + Oxygen <=> 3,4-Dihydroxy-5-polyprenylbenzoate + H2O
3,4-Dihydroxy-5-polyprenylbenzoate + S-Adenosyl-L-methionine <=> 3-Methoxy-4-hydroxy-5-polyprenylbenzoate + S-Adenosyl-L-homocysteine
3-Methoxy-4-hydroxy-5-polyprenylbenzoate <=> 2-Polyprenyl-6-methoxyphenol + CO2
Glycyl-tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine <=> tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)-D-alanyl-D-alanine
2 Glycyl-tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)-D-alanyl-D-alanine <=> 2 tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)3-D-alanyl-D-alanine
2 Glycyl-tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)3-D-alanyl-D-alanine <=> 2 tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)5-D-alanyl-D-alanine
L-Alanyl-tRNA + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine <=> tRNA(Ala) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl)-D-alanyl-D-alanine
L-Alanyl-tRNA + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl)-D-alanyl-D-alanine <=> tRNA(Ala) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl-L-alanyl)-D-alanyl-D-alanine
Homogentisate + all-trans-Nonaprenyl diphosphate <=> 2-Methyl-6-solanyl-1,4-benzoquinol + Diphosphate + CO2
1,8-Cineole + Reduced flavodoxin + Oxygen <=> 6-endo-Hydroxycineole + Oxidized flavodoxin + H2O
Geraniol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (6E)-8-Hydroxygeraniol + [Oxidized NADPH---hemoprotein reductase] + H2O
(S)-Reticuline + S-Adenosyl-L-methionine <=> Laudanine + S-Adenosyl-L-homocysteine
(R)-Reticuline + S-Adenosyl-L-methionine <=> Laudanine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + (S)-Canadine <=> S-Adenosyl-L-homocysteine + (S)-N-Methylcanadine
(S)-Reticuline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-Corytuberine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(S)-Corytuberine + S-Adenosyl-L-methionine <=> Magnoflorine + S-Adenosyl-L-homocysteine
Amino acid <=> Homoamino acid
S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + 3'-Hydroxy-N-methyl-(S)-coclaurine
Tetrahydropalmatine + 2 Oxygen + H+ <=> Palmatine + 2 Hydrogen peroxide
p-Coumaroyl-CoA + Malonyl-CoA + Hexanoyl-CoA + H2O <=> 1-(4-Hydroxyphenyl)-1-decene-3,5-dione + 3 CoA + 2 CO2
Feruloyl-CoA + Malonyl-CoA + Hexanoyl-CoA + H2O <=> 1-Dehydro-[6]-gingerdione + 3 CoA + 2 CO2
1-(4-Hydroxyphenyl)-1-decene-3,5-dione <=> 5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone
1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone
1-Dehydro-[6]-gingerdione <=> [6]-Gingerol
1-(4-Hydroxyphenyl)-1-decene-3,5-dione <=> 1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione
5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone
1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione + S-Adenosyl-L-methionine <=> 1-Dehydro-[6]-gingerdione + S-Adenosyl-L-homocysteine
1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone + S-Adenosyl-L-methionine <=> [6]-Gingerol + S-Adenosyl-L-homocysteine
p-Coumaroyl-CoA + Malonyl-CoA <=> p-Coumaroyl-diketide-CoA + CoA + CO2
Feruloyl-CoA + Malonyl-CoA <=> Feruloyl-diketide-CoA + CoA + CO2
p-Coumaroyl-diketide-CoA + p-Coumaroyl-CoA + H2O <=> Bisdemethoxycurcumin + 2 CoA + CO2
p-Coumaroyl-diketide-CoA + Feruloyl-CoA + H2O <=> Demethoxycurcumin + 2 CoA + CO2
Feruloyl-diketide-CoA + p-Coumaroyl-CoA + H2O <=> Demethoxycurcumin + 2 CoA + CO2
Feruloyl-diketide-CoA + Feruloyl-CoA + H2O <=> Curcumin + 2 CoA + CO2
Bisdemethoxycurcumin <=> Demethoxycurcumin
Demethoxycurcumin <=> Curcumin
Curcumin + UDP-glucose <=> Curcumin monoglucoside + UDP
Curcumin monoglucoside + UDP-glucose <=> Curcumin diglucoside + UDP
Cinnamoyl-CoA + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> p-Coumaroyl-CoA + [Oxidized NADPH---hemoprotein reductase] + H2O
2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + UDP-glucose <=> cyclo-Dopa 5-O-glucoside + UDP
cyclo-Dopa 5-O-glucoside + UDP-glucuronate <=> cyclo-Dopa-glucuronylglucoside + UDP
cyclo-Dopa-glucuronylglucoside + Betalamic acid <=> Amaranthin + H2O
Amaranthin + 1-O-Feruloyl-beta-D-glucose <=> Celosianin II + D-Glucose
cyclo-Dopa 5-O-glucoside + Betalamic acid <=> Betanin + H2O
2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + Betalamic acid <=> Betanidin + H2O
Betanidin + UDP-glucose <=> Betanin + UDP
Betanin + 1-O-Feruloyl-beta-D-glucose <=> Lampranthin II + D-Glucose
Betanin + UDP-glucuronate <=> Amaranthin + UDP
L-Tyrosine + Betalamic acid <=> Portulacaxanthin II + H2O
Portulacaxanthin II + Oxygen + Dopaxanthin <=> Dopaxanthin + H2O + Dopaxanthin quinone
3,4-Dihydroxy-L-phenylalanine + Betalamic acid <=> Dopaxanthin + H2O
2 Dopaxanthin + Oxygen <=> 2 Dopaxanthin quinone + 2 H2O
Dopaxanthin quinone <=> Betanidin
Betanidin + UDP-glucose <=> Gomphrenin-I + UDP
3-Methoxytyramine + Betalamic acid <=> 3-Methoxytyramine-betaxanthin + H2O
2 Dopamine + Oxygen <=> 2 Dopamine quinone + 2 H2O
Dopamine quinone <=> 2-Descarboxy-cyclo-dopa
2-Descarboxy-cyclo-dopa + Betalamic acid <=> 2-Descarboxy-betanidin + H2O
Dopamine + Betalamic acid <=> Miraxanthin-V + H2O
3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 4,5-seco-Dopa
4,5-seco-Dopa <=> Betalamic acid + H2O
Benzoate + NADPH + Oxygen <=> Salicylate + NADP+ + H2O
UDP-glucose + Ferulate <=> 1-O-Feruloyl-beta-D-glucose + UDP
Teasterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Oxateasterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Typhasterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Oxatyphasterol + [Oxidized NADPH---hemoprotein reductase] + H2O
7-Oxateasterone <=> 7-Oxatyphasterol
1-Guanidino-1-deoxy-scyllo-inositol <=> 1D-1-Guanidino-1-deoxy-3-dehydro-scyllo-inositol
ATP + 1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol <=> ADP + N1-Amidinostreptamine 6-phosphate
UTP + alpha-D-Aldose 1-phosphate <=> Diphosphate + UDP-sugar
3,4-Dihydroxy-L-phenylalanine + NADH + H+ <=> 3,4-Dihydroxyphenylpropanoate + NAD+ + Ammonia
3,4-Dihydroxyphenylpropanoate <=> (R)-3-(3,4-Dihydroxyphenyl)lactate
Dopaquinone + L-Cysteine <=> Cysteinyldopa
Cysteinyldopa <=> Phaeomelanin
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine + H2O <=> UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + D-Alanine
(+)-epi-Isozizaene + 2 Reduced [2Fe-2S] ferredoxin + 2 H+ + Oxygen <=> (5S)-Albaflavenol + 2 Oxidized [2Fe-2S] ferredoxin + H2O
(5S)-Albaflavenol + 2 Reduced [2Fe-2S] ferredoxin + 2 H+ + Oxygen <=> Albaflavenone + 2 Oxidized [2Fe-2S] ferredoxin + 2 H2O
(+)-epi-Isozizaene + 2 Reduced [2Fe-2S] ferredoxin + 2 H+ + Oxygen <=> (5R)-Albaflavenol + 2 Oxidized [2Fe-2S] ferredoxin + H2O
(5R)-Albaflavenol + 2 Reduced [2Fe-2S] ferredoxin + 2 H+ + Oxygen <=> Albaflavenone + 2 Oxidized [2Fe-2S] ferredoxin + 2 H2O
Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-Glutamine + ATP + H2O <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine + L-Glutamate + ADP + Orthophosphate
UDP-N-acetyl-alpha-D-glucosamine + di-trans,poly-cis-Undecaprenyl phosphate <=> N-Acetyl-D-glucosaminyldiphosphoundecaprenol + UMP
alpha-D-Galactosyl-diphosphoundecaprenol + dTDP-L-rhamnose <=> alpha-L-Rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol + dTDP
alpha-L-Rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol + GDP-mannose <=> D-Mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid + GDP
Limonoate A-ring-lactone + UDP-glucose <=> Glucosyl-limonin + UDP
Phosphonoacetaldehyde + NADPH + H+ <=> 2-Hydroxyethylphosphonate + NADP+
2-Hydroxyethylphosphonate + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> (S)-2-Hydroxypropylphosphonate + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine
(S)-2-Hydroxypropylphosphonate + Hydrogen peroxide <=> Fosfomycin + 2 H2O
2-Hydroxyethylphosphonate + Oxygen <=> Hydroxymethylphosphonate + Formate
Hydroxymethylphosphonate <=> Formylphosphonate
Formylphosphonate <=> Phosphonoformate
Phosphonoformate + CTP <=> Phosphonoformyl-CMP + Diphosphate
1-Carboxyvinyl carboxyphosphonate <=> Carboxyphosphonopyruvate
Carboxyphosphonopyruvate <=> 3-(Hydrohydroxyphosphoryl)pyruvate + CO2
3-(Hydrohydroxyphosphoryl)pyruvate + Acetyl-CoA + H2O <=> 2-Phosphinomethylmalate + CoA
Demethylphosphinothricin + Acetyl-CoA <=> N-Acetyldemethylphosphinothricin + CoA
N-Acetyldemethylphosphinothricin + 2 L-Alanine + 3 ATP + H2O <=> N-Acetyldemethylphosphinothricin tripeptide + 3 AMP + 3 Diphosphate
N-Acetyldemethylphosphinothricin + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> N-Acetylphosphinothricin + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine
N-Acetylphosphinothricin + H2O <=> L-Phosphinothricin + Acetate
N-Acetyldemethylphosphinothricin tripeptide + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> N-Acetylbialaphos + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine
N-Acetylbialaphos + H2O <=> Bialaphos + Acetate
Deamino-alpha-keto-demethylphosphinothricin <=> Demethylphosphinothricin
2-Dehydro-L-idonate + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+
5-Dehydro-D-gluconate + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+
L-Idonate + NADP+ <=> 2-Dehydro-L-idonate + NADPH + H+
(R)-2-(Phosphonomethyl)malate <=> 2-Oxo-4-phosphonobutanoate
2-Oxo-4-phosphonobutanoate <=> FR 900098
Phosphonoacetaldehyde <=> Rhizocticin B
Phosphonoacetaldehyde <=> Rhizocticin A
Phosphonoacetaldehyde <=> Rhizocticin C
Phosphonoacetaldehyde <=> Rhizocticin D
Phosphonoformyl-CMP + 3-Phospho-D-glycerate <=> 1-Carboxyvinyl carboxyphosphonate + CMP + Orthophosphate
3-Phosphinomethylmalate <=> Deamino-alpha-keto-demethylphosphinothricin
8'-apo-beta-Carotenol + Oxygen <=> 14'-apo-beta-Carotenal + 7-Hydroxy-6-methylhepta-3,5-dienal
2-Deoxy-scyllo-inosose + L-Glutamine <=> 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate
3-Amino-2,3-dideoxy-scyllo-inosose + L-Glutamine <=> 2-Deoxystreptamine + 2-Oxoglutaramate
2-Deoxy-scyllo-inosamine + NAD+ <=> 3-Amino-2,3-dideoxy-scyllo-inosose + NADH + H+
2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine <=> 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine
UDP-N-acetyl-alpha-D-glucosamine + 2-Deoxystreptamine <=> UDP + 2'-N-Acetylparomamine
2'-N-Acetylparomamine + H2O <=> Paromamine + Acetate
Paromamine + Oxygen <=> 6'-Dehydro-6'-oxoparomamine + Hydrogen peroxide
Neamine + 2-Oxoglutarate <=> 6'-Dehydro-6'-oxoparomamine + L-Glutamate
5-Phospho-alpha-D-ribose 1-diphosphate + Neamine <=> Diphosphate + 5''-Phosphoribostamycin
5''-Phosphoribostamycin + H2O <=> Ribostamycin + Orthophosphate
UDP-N-acetyl-alpha-D-glucosamine + Ribostamycin <=> UDP + 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C
2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C + H2O <=> 6'''-Deamino-6'''-hydroxyneomycin C + Acetate
6'''-Deamino-6'''-hydroxyneomycin C + Oxygen <=> 6'''-Deamino-6'''-oxoneomycin C + Hydrogen peroxide
Neomycin C + 2-Oxoglutarate <=> 6'''-Deamino-6'''-oxoneomycin C + L-Glutamate
Neomycin C <=> Neomycin B
ATP + L-Glutamate + Acyl-carrier protein <=> ADP + Orthophosphate + gamma-L-Glutamyl-[acp]
ATP + L-Glutamate + 4-Aminobutyryl-[acp] <=> ADP + Orthophosphate + 4-(gamma-L-Glutamylamino)butanoyl-[acp]
gamma-L-Glutamyl-[acp] <=> 4-Aminobutyryl-[acp] + CO2
4-(gamma-L-Glutamylamino)butanoyl-[acp] + Reduced FMN + Oxygen <=> 4-(gamma-L-Glutamylamino)-(2S)-2-hydroxybutanoyl-[acp] + FMN + H2O
4-(gamma-L-Glutamylamino)-(2S)-2-hydroxybutanoyl-[acp] + Ribostamycin <=> Acyl-carrier protein + gamma-L-Glutamyl-butirosin B
gamma-L-Glutamyl-butirosin B <=> Butirosin B + 5-Oxoproline
Butirosin B <=> Butirosin A
2 Flaviolin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 3,3'-Biflaviolin + 2 Oxidized ferredoxin + 2 H2O
2 Flaviolin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 3,8'-Biflaviolin + 2 Oxidized ferredoxin + 2 H2O
7(1)-Hydroxychlorophyllide a + NAD+ <=> Chlorophyllide b + NADH + H+
7(1)-Hydroxychlorophyllide a + NADP+ <=> Chlorophyllide b + NADPH + H+
3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD+ <=> Momilactone A + NADH + H+
3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NADP+ <=> Momilactone A + NADPH + H+
8-p-Menthen-2-ol + NAD+ <=> p-Menth-8-en-2-one + NADH + H+
p-Menth-8-ene-1,2-diol + NAD+ <=> 1-Hydroxy-p-menth-8-en-2-one + NADH + H+
2 3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 2 3-(3,4-Dihydroxyphenyl)pyruvate + 2 Ammonia
Pheophorbide a + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Red chlorophyll catabolite + 2 Oxidized ferredoxin
Sophoraflavanone B + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Leachianone G + [Oxidized NADPH---hemoprotein reductase] + H2O
Pulegone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (+)-Menthofuran + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ATP + HCO3- + Butanoyl-CoA + H+ <=> ADP + Orthophosphate + (2S)-Ethylmalonyl-CoA
(-)-Menthone + NADPH + H+ + Oxygen <=> (4R,7S)-7-Isopropyl-4-methyloxepan-2-one + NADP+ + H2O
6-Deoxy-L-galactose + NAD+ <=> L-Fucono-1,5-lactone + NADH + H+
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose <=> dTDP-3-oxo-2,6-dideoxy-D-glucose
dTDP-3-oxo-2,6-dideoxy-D-glucose <=> dTDP-2,6-dideoxy-D-kanosamine
dTDP-2,6-dideoxy-D-kanosamine <=> dTDP-D-angolosamine
dTDP-4-oxo-2,6-dideoxy-D-glucose + Reduced ferredoxin + H+ <=> dTDP-4-oxo-2,3,6-trideoxy-D-glucose + H2O + Oxidized ferredoxin
dTDP-4-oxo-2,3,6-trideoxy-D-glucose + L-Glutamate <=> dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose + 2-Oxoglutarate
dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-forosamine + 2 S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose
dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose
dTDP-L-rhamnose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-glucose + NADPH + H+
Malonyl-[acyl-carrier protein] + Biotinyl-[protein] <=> Acetyl-[acyl-carrier protein] + Carboxybiotinyl-[protein]
Carbamoyl phosphate + N2-Succinyl-L-ornithine <=> Orthophosphate + N-Succinyl-L-citrulline
Acetyl-CoA + L-Phosphinothricin <=> CoA + N-Acetylphosphinothricin
Butyryl-[acp] + S-Adenosyl-L-methionine <=> Acyl-carrier protein + 5'-Methylthioadenosine + N-Butyryl-L-homoserine lactone
Acyl-[acyl-carrier protein] + S-Adenosyl-L-methionine <=> Acyl-carrier protein + 5'-Methylthioadenosine + N-Acyl-L-homoserine lactone
Cholesterol + Sulfate <=> Cholesterol sulfate + H2O
Pregnenolone + Sulfate <=> 3beta-Hydroxypregn-5-en-20-one sulfate + H2O
Pregnenolone + NADPH + H+ + Oxygen <=> 7alpha-Hydroxypregnenolone + NADP+ + H2O
Acetyl-[acyl-carrier protein] + Malonate <=> Malonyl-[acyl-carrier protein] + Acetate
11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H+
ADP-glucose + D-Glucose <=> alpha,alpha-Trehalose + ADP
GDP-mannose + D-Fructose 6-phosphate <=> GDP + beta-D-Fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate
2 Dimethylallyl diphosphate <=> Diphosphate + Chrysanthemyl diphosphate
11-Deoxycorticosterone + 3 Reduced adrenal ferredoxin + 3 Oxygen <=> Aldosterone + 3 Oxidized adrenal ferredoxin + 4 H2O
2 Dimethylallyl diphosphate <=> Diphosphate + Lavandulyl diphosphate
Dimethylallyl diphosphate + Naringenin <=> Diphosphate + Sophoraflavanone B
Dimethylallyl diphosphate + Leachianone G <=> Diphosphate + Sophoraflavanone G
Aldosterone <=> Aldosterone hemiacetal
11-Deoxycorticosterone + NADPH + H+ <=> 5alpha-Dihydrodeoxycorticosterone + NADP+
5alpha-Dihydrodeoxycorticosterone + NADPH + H+ <=> Allotetrahydrodeoxycorticosterone + NADP+
2-Amino-2-deoxyisochorismate + L-Glutamate <=> Chorismate + L-Glutamine
5alpha-Pregnane-3,20-dione + NADPH + H+ <=> Allopregnanolone + NADP+
5alpha-Pregnan-20alpha-ol-3-one + NADP+ <=> 5alpha-Pregnane-3,20-dione + NADPH + H+
5alpha-Pregnane-3alpha,20alpha-diol + NADP+ <=> Allopregnanolone + NADPH + H+
5alpha-Pregnan-20alpha-ol-3-one + NADPH + H+ <=> 5alpha-Pregnane-3alpha,20alpha-diol + NADP+
Dehydroepiandrosterone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 7alpha-Hydroxydehydroepiandrosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
ATP + N-Acetyl-D-hexosamine <=> ADP + N-Acetyl-alpha-D-hexosamine 1-phosphate
Dihydrotestosterone + NADPH + H+ <=> Androstan-3alpha,17beta-diol + NADP+
ATP + 5-PP-InsP5 <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
2 5,6-Dihydroxyindole-2-carboxylate + Oxygen <=> 2 5,6-Indolequinone-2-carboxylic acid + 2 H2O
CTP + 2,3-Bis-O-(geranylgeranyl)glycerol 1-phosphate <=> Diphosphate + CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol
N-Acetyl-D-galactosamine + ATP <=> N-Acetyl-alpha-D-galactosamine 1-phosphate + ADP
N-Acetyl-D-glucosamine + ATP <=> N-Acetyl-alpha-D-glucosamine 1-phosphate + ADP
N-Acylsphingosine + Phosphatidylcholine <=> Sphingomyelin + 1,2-Diacyl-sn-glycerol
N-Acyl-L-homoserine lactone + H2O <=> N-Acyl-L-homoserine
DIBOA-glucoside + 2-Oxoglutarate + Oxygen <=> TRIBOA-glucoside + Succinate + CO2
S-Adenosyl-L-methionine + TRIBOA-glucoside <=> S-Adenosyl-L-homocysteine + DIMBOA-glucoside
Pheophorbide a + H2O <=> Pyropheophorbide a + Methanol + CO2
Pheophorbide a + H2O <=> C-13(2)-Carboxypyropheophorbide a + Methanol
C-13(2)-Carboxypyropheophorbide a <=> Pyropheophorbide a + CO2
Cholesterol + 3'-Phosphoadenylyl sulfate <=> Cholesterol sulfate + Adenosine 3',5'-bisphosphate
Pregnenolone + 3'-Phosphoadenylyl sulfate <=> 3beta-Hydroxypregn-5-en-20-one sulfate + Adenosine 3',5'-bisphosphate
7-Isopropyl-4-methyloxepan-2-one + H2O <=> 6-Hydroxy-3,7-dimethyloctanoate
11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 5-phosphate + Orthophosphate
beta-D-Fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate + H2O <=> beta-D-Fructofuranosyl-alpha-D-mannopyranoside + Orthophosphate
3 p-Coumaroyl-CoA + Spermidine <=> N1,N5,N10-Tricoumaroyl spermidine + 3 CoA
N1,N5,N10-Tricoumaroyl spermidine <=> N1,N5,N10-Tricaffeoyl spermidine
N1,N5,N10-Tricaffeoyl spermidine <=> N1,N5,N10-Triferuloyl spermidine
N1,N5,N10-Triferuloyl spermidine <=> N1,N5,N10-Tri(hydroxyferuloyl) spermidine
N1,N5,N10-Tri(hydroxyferuloyl) spermidine + S-Adenosyl-L-methionine <=> N1,N5-Di(hydroxyferuloyl)-N10-sinapoyl spermidine + S-Adenosyl-L-homocysteine
beta-Carotene <=> Strigolactone ABC-rings
Strigolactone ABC-rings <=> 5-Deoxystrigol
5-Deoxystrigol <=> Strigol
3',5'-Cyclic diGMP + H2O <=> 5'-Phosphoguanylyl(3'->5')guanosine
Geranylgeranyl diphosphate + 2 H2O <=> Sclareol + Diphosphate
Geranylgeranyl diphosphate + H2O <=> Geranylgeraniol + Diphosphate
11-Dehydrocorticosterone <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione
Cortisol <=> 11beta-Hydroxyandrost-4-ene-3,17-dione
Umbelliferone + Dimethylallyl diphosphate <=> Demethylsuberosin + Diphosphate
Demethylsuberosin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Marmesin + [Oxidized NADPH---hemoprotein reductase] + H2O
(+)-Columbianetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Angelicin + [Oxidized NADPH---hemoprotein reductase] + Acetone + 2 H2O
UDP-L-arabinose <=> UDP-L-arabinofuranose
D-Allose 6-phosphate <=> D-Allulose 6-phosphate
D-Allulose 6-phosphate <=> beta-D-Fructose 6-phosphate
Primary fluorescent chlorophyll catabolite + 2 Oxidized ferredoxin <=> Red chlorophyll catabolite + 2 Reduced ferredoxin + 2 H+
Chlorophyllide + 2 H+ <=> Pheophorbide a + Magnesium cation
Acyl-CoA + 1-Acylglycerophosphoinositol <=> CoA + 1-Phosphatidyl-D-myo-inositol
Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine
Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol
Acyl-CoA + Monolysocardiolipin <=> CoA + Cardiolipin
Cardiolipin + H2O <=> Monolysocardiolipin + Fatty acid
4-(beta-D-Glucosyloxy)benzoate + H2O <=> 4-Hydroxybenzoate + D-Glucose
4-Hydroxybenzoate + Geranyl diphosphate <=> Geranyl-hydroxybenzoate + Diphosphate
Geranyl-hydroxybenzoate <=> Geranylhydroquinone
Geranylhydroquinone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3''-Hydroxy-geranylhydroquinone + [Oxidized NADPH---hemoprotein reductase] + H2O
3''-Hydroxy-geranylhydroquinone <=> Deoxyshikonin
Deoxyshikonin <=> Shikonin
Geranylhydroquinone <=> Dihydroshikonofuran
Dihydroshikonofuran <=> Dihydroechinofuran
ATP + Gentamicin A <=> Diphosphate + 2''-Adenylylgentamicin A
3 Cadaverine + 4 Pyruvate <=> 17-Oxosparteine + 4 L-Alanine + 3 H2O
17-Oxosparteine <=> Lupanine
Lupanine <=> 13-Hydroxylupanine
3,6-Dihydronicotinic acid <=> 3,6-Dihydropyridine
Piperideine <=> Piperidine
Chlorophyllide + 2 Reduced ferredoxin + ATP + H2O + 2 H+ <=> 3-Vinylbacteriochlorophyllide a + 2 Oxidized ferredoxin + ADP + Orthophosphate
3-Vinylbacteriochlorophyllide a + H2O <=> 3-Hydroxyethylbacteriochlorophyllide a
3-Hydroxyethylbacteriochlorophyllide a + NAD+ <=> Bacteriochlorophyllide a + NADH + H+
Bacteriochlorophyllide a <=> Bacteriochlorophyllide b
Chlorophyllide + H2O <=> 3-Hydroxyethylchlorophyllide a
3-Hydroxyethylchlorophyllide a + 2 Reduced ferredoxin + ATP + H2O + 2 H+ <=> 3-Hydroxyethylbacteriochlorophyllide a + 2 Oxidized ferredoxin + ADP + Orthophosphate
Chlorophyllide + H2O <=> 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + Methanol + CO2
Bacteriochlorophyllide d + S-Adenosyl-L-methionine <=> Bacteriochlorophyllide c + S-Adenosyl-L-homocysteine
Bacteriochlorophyllide c + trans,trans-Farnesyl diphosphate <=> Bacteriochlorophyll c + Diphosphate
Bacteriochlorophyllide d + trans,trans-Farnesyl diphosphate <=> Bacteriochlorophyll d + Diphosphate
7(1)-Hydroxychlorophyllide a <=> Chlorophyllide
Chlorophyllide b + Phytyl diphosphate <=> Chlorophyll b + Diphosphate
Chlorophyll b + H2O <=> Chlorophyllide b + Phytol
7(1)-Hydroxychlorophyll a + NAD+ <=> Chlorophyll b + NADH + H+
7(1)-Hydroxychlorophyll a + NADP+ <=> Chlorophyll b + NADPH + H+
7(1)-Hydroxychlorophyll a + 2 Reduced ferredoxin + 2 H+ <=> Chlorophyll a + 2 Oxidized ferredoxin + H2O
1,2-Diacyl-sn-glycerol + S-Adenosyl-L-methionine <=> Diacylglycerylhomoserine + 5'-Methylthioadenosine
Diacylglycerylhomoserine + 3 S-Adenosyl-L-methionine <=> Diacylglyceryl-N,N,N-trimethylhomoserine + 3 S-Adenosyl-L-homocysteine
N1-Acetylspermidine + Oxygen + H2O <=> Putrescine + 3-Acetamidopropanal + Hydrogen peroxide
N8-Acetylspermidine + Oxygen + H2O <=> 1,3-Diaminopropane + N4-Acetylaminobutanal + Hydrogen peroxide
Spermine + Oxygen + H2O <=> Spermidine + 3-Aminopropanal + Hydrogen peroxide
Spermidine + Oxygen + H2O <=> Putrescine + 3-Aminopropanal + Hydrogen peroxide
Diacetyl + NADH + H+ <=> (S)-Acetoin + NAD+
Putrescine + L-Aspartate 4-semialdehyde + NADPH + H+ <=> Carboxyspermidine + H2O + NADP+
1,3-Diaminopropane + L-Aspartate 4-semialdehyde + NADPH + H+ <=> Carboxynorspermidine + H2O + NADP+
Carboxyspermidine <=> Spermidine + CO2
Carboxynorspermidine <=> Norspermidine + CO2
Reduced FMN + Oxygen <=> Dimethylbenzimidazole + D-Erythrose 4-phosphate + H2O
beta-D-Fructose 6-phosphate + ADP <=> beta-D-Fructose 1,6-bisphosphate + AMP
alpha-D-Glucose + ADP <=> alpha-D-Glucose 6-phosphate + AMP
beta-D-Glucose + ADP <=> beta-D-Glucose 6-phosphate + AMP
ATP + Phytic acid <=> ADP + 5-PP-InsP5
Benzoate + Pyruvate <=> Pyruvophenone + CO2
Pyruvophenone <=> D-Cathinone
2-Methylpropanoyl-CoA + 3 Malonyl-CoA <=> 8-Methyl-6-nonenoic acid
Tetrahydrofolate + Formaldehyde <=> 5,10-Methylenetetrahydrofolate + H2O
Formate <=> CO2
Methanophenazine + Hydrogen <=> Dihydromethanophenazine
Acetyl-CoA + 5,6,7,8-Tetrahydromethanopterin <=> CoA + 5-Methyl-5,6,7,8-tetrahydromethanopterin + CO
Propanal + NAD+ + CoA <=> Propanoyl-CoA + NADH + H+
Methanol + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + H2O
L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O
D-Fructose 1,6-bisphosphate <=> 3-Phospho-D-glycerate
Bis(4-hydroxyphenyl)methane <=> Bis(4-hydroxyphenyl)methanol
Bis(4-hydroxyphenyl)methanol <=> 4,4'-Dihydroxybenzophenone
4,4'-Dihydroxybenzophenone <=> 4-Hydroxyphenyl-4-hydroxybenzoate
4-Hydroxyphenyl-4-hydroxybenzoate + H2O <=> 4-Hydroxybenzoate + Hydroquinone
Feruloyl-CoA + 16-Hydroxypalmitate <=> CoA + 16-Feruloyloxypalmitate
N-Acetyl-L-citrulline + H2O <=> Acetate + L-Citrulline
Palustradiene <=> Palustradienol
Palustradienol <=> Palustradienal
Palustradienal <=> Palustric acid
Copalyl diphosphate <=> Isopimara-7,15-diene + Diphosphate
Isopimara-7,15-diene <=> Isopimaradienol
Isopimaradienol <=> Isopimaradienal
Isopimaradienal <=> Isopimaric acid
9alpha-Copalyl diphosphate <=> Stemar-13-ene + Diphosphate
9alpha-Copalyl diphosphate <=> Stemod-13(17)-ene + Diphosphate
9alpha-Copalyl diphosphate <=> 9beta-Pimara-7,15-diene + Diphosphate
9beta-Pimara-7,15-dien-19-oate <=> 3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide
ent-Copalyl diphosphate <=> ent-Cassa-12,15-diene + Diphosphate
ent-Copalyl diphosphate <=> (+)-Sandaracopimaradiene + Diphosphate
ent-Copalyl diphosphate <=> ent-Pimara-8(14),15-diene + Diphosphate
Geranylgeraniol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Plaunotol + [Oxidized NADPH---hemoprotein reductase] + H2O
Geranylgeranyl diphosphate <=> Fusicocca-2,10(14)-diene + Diphosphate
Trimethylamine + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Dimethylamine
2,5-Dihydroxypyridine + Oxygen <=> N-Formylmaleamic acid
N-Formylmaleamic acid + H2O <=> Maleamate + Formate
Ethanol + 2 Ferricytochrome cL <=> Acetaldehyde + 2 Ferrocytochrome cL + 2 H+
2-Chloroethanol + 2 Ferricytochrome cL <=> Chloroacetaldehyde + 2 Ferrocytochrome cL + 2 H+
S-(Hydroxymethyl)mycothiol + NAD+ <=> S-Formylmycothiol + NADH + H+
1,2,3,4-Tetrachlorobenzene + Oxygen + NADH + H+ <=> cis-Chlorobenzene dihydrodiol + NAD+
1,2,3,4-Tetrachlorobenzene + Oxygen + NADPH + H+ <=> cis-Chlorobenzene dihydrodiol + NADP+
cis-Chlorobenzene dihydrodiol + NAD+ <=> Tetrachlorocatechol + NADH + H+
cis-Chlorobenzene dihydrodiol + NADP+ <=> Tetrachlorocatechol + NADPH + H+
Tetrachlorocatechol + Oxygen <=> Tetrachloro-cis,cis-muconate
Tetrachloro-cis,cis-muconate <=> 2,3,5-Trichlorodienelactone + Hydrochloric acid
2,3,5-Trichlorodienelactone + H2O <=> 2,3,5-Trichloromaleylacetate
2,3,5-Trichloromaleylacetate + 2 NADH + 2 H+ <=> 2,4-Dichloro-3-oxoadipate + 2 NAD+ + Hydrochloric acid
2,3,5-Trichloromaleylacetate + 2 NADPH + 2 H+ <=> 2,4-Dichloro-3-oxoadipate + 2 NADP+ + Hydrochloric acid
2,4-Dichloro-3-oxoadipate <=> CO2
trans,trans-Farnesyl diphosphate + H2O <=> 8-epi-Cedrol + Diphosphate
Trichloroethene + NADH + H+ + Oxygen <=> TCE epoxide + NAD+ + H2O
TCE epoxide <=> CO
TCE epoxide <=> Dichloroacetate
TCE epoxide <=> Glyoxylate
TCE epoxide <=> Formate
Trichloroethene <=> Chloral
Trichloroethene <=> TCE epoxide
1,1,1-Trichloroethane + NADH + H+ + Oxygen <=> Trichloroethanol + NAD+ + H2O
Trichloroethanol <=> Chloral
Chloral <=> Trichloroacetate
Trichloroethene + Oxygen + H2O + NADH + H+ <=> Glyoxylate + 3 Hydrochloric acid + NAD+
Trichloroethene + Oxygen + 2 H2O + NADH + H+ <=> 2 Formate + 3 Hydrochloric acid + NAD+
Sulfoacetaldehyde <=> Coenzyme M
1,1,1-Trichloroethane <=> 1,1-Dichloroethane + Hydrochloric acid
1,1-Dichloroethane <=> Chloroethane + Hydrochloric acid
Chloroethane + Oxygen + Reduced acceptor <=> Acetaldehyde + Hydrochloric acid + Acceptor + H2O
Trichloroacetate + 2 H2O <=> Oxalate + 3 Hydrochloric acid
Trichloroacetate <=> CO2
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-9,10-dihydrodiol + NAD+
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-7,8-dihydrodiol + NAD+
Pyrene + Oxygen <=> cis-4,5-Dihydroxy-4,5-dihydropyrene
cis-4,5-Dihydroxy-4,5-dihydropyrene + NAD+ <=> 4,5-Dihydroxypyrene + NADH + H+
4,5-Dihydroxypyrene + Oxygen <=> Phenanthrene-4,5-dicarboxylate
Phenanthrene-4,5-dicarboxylate <=> Phenanthrene-4-carboxylate + CO2
Phenanthrene-4-carboxylate + Oxygen + NADH + H+ <=> cis-3,4-Phenanthrenedihydrodiol-4-carboxylate + NAD+
cis-3,4-Phenanthrenedihydrodiol-4-carboxylate <=> Phenanthrene-3,4-diol + CO2
Pyrene + Oxygen <=> Pyrene-4,5-oxide + H2O
Pyrene-4,5-oxide + H2O <=> trans-4,5-Dihydroxy-4,5-dihydropyrene
Pyrene + Oxygen <=> Pyrene-1,2-oxide + H2O
Pyrene-1,2-oxide <=> 1-Hydroxypyrene
1-Hydroxypyrene + Oxygen <=> 1-Hydroxypyrene-6,7-oxide + H2O
1-Hydroxypyrene-6,7-oxide <=> 1,6-Dihydroxypyrene
1,6-Dihydroxypyrene <=> Pyrene-1,6-dione
1-Hydroxypyrene + Oxygen <=> 1-Hydroxypyrene-7,8-oxide + H2O
1-Hydroxypyrene-7,8-oxide <=> 1,8-Dihydroxypyrene
1,8-Dihydroxypyrene <=> Pyrene-1,8-dione
1-Hydroxypyrene + S-Adenosyl-L-methionine <=> 1-Methoxypyrene + S-Adenosyl-L-homocysteine
1-Methoxypyrene + Oxygen <=> 1-Methoxypyrene-6,7-oxide + H2O
1-Methoxypyrene-6,7-oxide <=> 1-Hydroxy-6-methoxypyrene
1-Hydroxy-6-methoxypyrene + CH3-R <=> 1,6-Dimethoxypyrene + R
1-Hydroxypyrene <=> 1-Pyrenylsulfate
Benzo[a]pyrene-cis-7,8-dihydrodiol + Oxygen <=> cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate
Benzo[a]pyrene-cis-9,10-dihydrodiol + NAD+ <=> 9,10-Dihydroxybenzo[a]pyrene + NADH + H+
9,10-Dihydroxybenzo[a]pyrene + Oxygen <=> cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate
cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate <=> 10-Oxabenzo[def]chrysen-9-one + Formate
2-Dehydro-3-deoxy-D-xylonate <=> 2,5-Dioxopentanoate + H2O
C-9 Reduced nonaketamide <=> Nonaketamide monocyclic intermediate + 2 H2O
Nonaketamide monocyclic intermediate <=> Nonaketamide tricyclic intermediate
S-Adenosyl-L-methionine + Pretetramid <=> S-Adenosyl-L-homocysteine + 6-Methylpretetramide
6-Methylpretetramide + 2 NADPH + 2 H+ + 2 Oxygen <=> 4-Keto-anhydrotetracycline + 2 NADP+ + 2 H2O
4-Amino-anhydrotetracycline + 2 S-Adenosyl-L-methionine <=> Anhydrotetracycline + 2 S-Adenosyl-L-homocysteine
Oxytetracycline + Coenzyme F420 <=> 5a,11a-Dehydrooxytetracycline + Reduced coenzyme F420
Anhydrochlortetracycline + Oxygen + NADPH + H+ <=> 5a,11a-Dehydrochlortetracycline + NADP+ + H2O
5a,11a-Dehydrochlortetracycline + NADPH + H+ <=> Chlortetracycline + NADP+
ATP + Malonyl-CoA + L-Glutamine + H2O <=> AMP + Diphosphate + Malonamoyl-CoA + L-Glutamate
Nonaketamide tricyclic intermediate <=> Pretetramid
4-Keto-anhydrotetracycline <=> 4-Amino-anhydrotetracycline
5a,11a-Dehydrotetracycline + NADPH + H+ + Oxygen <=> 5a,11a-Dehydrooxytetracycline + NADP+ + H2O
4-Ketoanhydrochlortetracycline <=> 4-Aminoanhydrochlortetracycline
4-Aminoanhydrochlortetracycline + 2 S-Adenosyl-L-methionine <=> Anhydrochlortetracycline + 2 S-Adenosyl-L-homocysteine
2,4-Dichlorotoluene + NADH + Oxygen + H+ <=> 4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+
cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate <=> 7,8-Dihydropyrene-8-carboxylate
cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate <=> 7,8-Dihydropyrene-7-carboxylate
Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-4,5-dihydrodiol + NAD+
Benzo[a]pyrene-cis-4,5-dihydrodiol <=> 4,5-Dihydroxybenzo[a]pyrene
4,5-Dihydroxybenzo[a]pyrene + Oxygen <=> 4,5-Chrysenedicarboxylate
4,5-Chrysenedicarboxylate <=> 4-Chrysenecarboxylate + CO2
4,5-Chrysenedicarboxylate <=> 5-Chrysenecarboxylate + CO2
Benzo[a]pyrene + NADH + H+ + Oxygen <=> Benzo[a]pyrene-cis-11,12-dihydrodiol + NAD+
Benzo[a]pyrene + Oxygen <=> Benzo[a]pyrene-11,12-epoxide
Benzo[a]pyrene-11,12-epoxide + H2O <=> Benzo[a]pyrene-trans-11,12-dihydrodiol
Benzo[a]pyrene-trans-11,12-dihydrodiol <=> 11,12-Dihydroxybenzo[a]pyrene
4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 4,6-Dichloro-3-methylcatechol + NADH + H+
4,6-Dichloro-3-methylcatechol + Oxygen <=> 3,5-Dichloro-2-methylmuconate
3,5-Dichloro-2-methylmuconate <=> 3,5-Dichloro-2-methylmuconolactone
Benzo[a]pyrene-cis-11,12-dihydrodiol <=> 11,12-Dihydroxybenzo[a]pyrene
3,5-Dichloro-2-methylmuconolactone <=> 3-Chloro-2-methyldienelactone + Hydrochloric acid
Pyrene-4,5-dione <=> Phenanthrene-4,5-dicarboxylate
Pyrene-4,5-dione + NADH + H+ <=> 4,5-Dihydroxypyrene + NAD+
3-Chloro-2-methyldienelactone + H2O <=> 3-Chloro-2-methylmaleylacetate
3,5-Dichloro-2-methylmuconate <=> 2-Chloro-5-methyl-cis-dienelactone + Hydrochloric acid
2-Chloro-5-methyl-cis-dienelactone + H2O <=> 2-Chloro-5-methylmaleylacetate
2-Chloro-5-methylmaleylacetate + NADH + H+ <=> 5-Methylmaleylacetate + NAD+ + Hydrochloric acid
5-Methylmaleylacetate + NADH + H+ <=> 2-Methyl-3-oxoadipate + NAD+
3-Methylmuconolactone <=> 4-Methyl-3-oxoadipate-enol-lactone
4-Methyl-3-oxoadipate-enol-lactone + H2O <=> 4-Methyl-3-oxoadipate
Phthalate + Oxygen + NADH + H+ <=> Phthalate 3,4-cis-dihydrodiol + NAD+
Phthalate 3,4-cis-dihydrodiol + NAD+ <=> 3,4-Dihydroxyphthalate + NADH + H+
3-Methyl-cis,cis-hexadienedioate <=> 3-Methylmuconolactone
2-Amino-4-nitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diaminotoluene + 3 NAD+ + 2 H2O
2,4-Dinitrotoluene + 3 NADH + 3 H+ <=> 2-Amino-4-nitrotoluene + 3 NAD+ + 2 H2O
2,4-Dinitrotoluene + 3 NADH + 3 H+ <=> 4-Amino-2-nitrotoluene + 3 NAD+ + 2 H2O
2,4-Dinitrotoluene + NADH + Oxygen + H+ <=> 4-Methyl-5-nitrocatechol + NAD+ + Nitrite
4-Methyl-5-nitrocatechol + NADPH + Oxygen + H+ <=> 2-Hydroxy-5-methylquinone + NADP+ + Nitrite + H2O
4-Amino-2-nitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diaminotoluene + 3 NAD+ + 2 H2O
2-Hydroxy-5-methylquinone + NADH + H+ <=> 2,4,5-Trihydroxytoluene + NAD+
2,4,5-Trihydroxytoluene + Oxygen <=> cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate
cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate + H2O <=> (S)-Methylmalonate semialdehyde + Pyruvate
4,5-Dihydroxypyrene <=> Pyrene-4,5-dione
2-Amino-4-nitrotoluene + 3 NADPH + 3 H+ <=> 2,4-Diaminotoluene + 3 NADP+ + 2 H2O
2,4-Dinitrotoluene + 3 NADPH + 3 H+ <=> 2-Amino-4-nitrotoluene + 3 NADP+ + 2 H2O
2,4-Dinitrotoluene + 3 NADPH + 3 H+ <=> 4-Amino-2-nitrotoluene + 3 NADP+ + 2 H2O
4-Amino-2-nitrotoluene + 3 NADPH + 3 H+ <=> 2,4-Diaminotoluene + 3 NADP+ + 2 H2O
2-cis,6-trans-Farnesyl diphosphate + 7 Isopentenyl diphosphate <=> trans,octacis-Decaprenyl diphosphate + 7 Diphosphate
trans,trans-Farnesyl diphosphate + 3 Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + 3 Diphosphate
Geranylgeranyl diphosphate + 2 Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + 2 Diphosphate
trans,trans-Farnesyl diphosphate + 4 Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + 4 Diphosphate
trans,trans-Farnesyl diphosphate + 5 Isopentenyl diphosphate <=> all-trans-Octaprenyl diphosphate + 5 Diphosphate
trans,trans-Farnesyl diphosphate + 7 Isopentenyl diphosphate <=> all-trans-Decaprenyl diphosphate + 7 Diphosphate
Geranyl diphosphate + 7 Isopentenyl diphosphate <=> all-trans-Nonaprenyl diphosphate + 7 Diphosphate
Geranylgeranyl diphosphate + 5 Isopentenyl diphosphate <=> all-trans-Nonaprenyl diphosphate + 5 Diphosphate
Cyclohex-1-ene-1-carboxyl-CoA + Electron-transferring flavoprotein <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Reduced electron-transferring flavoprotein
2-Oxo-4-hydroxy-5-aminovalerate <=> 2,5-Dioxopentanoate + Ammonia
L-Tyrosine + Pyruvate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Alanine
Feruloyl-CoA + Agmatine <=> CoA + Feruloylagmatine
p-Coumaroyl-CoA + Putrescine <=> CoA + p-Coumaroylputrescine
Feruloyl-CoA + Putrescine <=> CoA + Feruloylputrescine
8 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 8 CO2 + 8 CoA
3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] <=> 7,9,12-Octaketide intermediate 1
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,9,12-Decaketide intermediate 1
3,5,7,9,11,13,15,17,19-Nonaoxo-henicosanoyl-[acp] <=> 7,9,12-Decaketide intermediate 4
7,9,12-Octaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Octaketide intermediate 2 + NADP+
7,9,12-Decaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Decaketide intermediate 2 + NADP+
7,9,12-Decaketide intermediate 4 + NADPH + H+ <=> 7,9,12-Decaketide intermediate 5 + NADP+
7,9,12-Octaketide intermediate 2 <=> 7,9,12-Octaketide intermediate 3 + 2 H2O
7,9,12-Decaketide intermediate 2 <=> 7,9,12-Decaketide intermediate 3 + 2 H2O
7,9,12-Decaketide intermediate 5 <=> 7,9,12-Decaketide intermediate 6 + 2 H2O
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,12-Decaketide intermediate 1 + H2O
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 9,14-Decaketide intermediate 1 + 2 H2O
Syringic acid + Tetrahydrofolate <=> 3-O-Methylgallate + 5-Methyltetrahydrofolate
3-O-Methylgallate + Tetrahydrofolate <=> Gallate + 5-Methyltetrahydrofolate
3-O-Methylgallate + Oxygen <=> 4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate
4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate + H2O <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate + Methanol
4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate <=> 2-Pyrone-4,6-dicarboxylate + Methanol
5,5'-Dehydrodivanillate + Oxygen + NADPH + H+ <=> 2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl + NADP+ + H2O + Formaldehyde
2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl + Oxygen <=> 4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate
4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate + H2O <=> 5-Carboxyvanillic acid + 4-Methylene-2-oxoglutarate
5-Carboxyvanillic acid <=> Vanillate + CO2
4-Hydroxybutanoic acid + ATP + CoA <=> 4-Hydroxybutyryl-CoA + AMP + Diphosphate
Succinyl-CoA + NADPH + H+ <=> Succinate semialdehyde + NADP+ + CoA
4-Hydroxybutanoic acid + NADP+ <=> Succinate semialdehyde + H+ + NADPH
3-Methylfumaryl-CoA + H2O <=> (3S)-Citramalyl-CoA
2-Methylfumaryl-CoA <=> 3-Methylfumaryl-CoA
3-Hydroxyaminophenol <=> 4-Aminocatechol
4-Aminocatechol + H2O <=> Benzene-1,2,4-triol + Ammonia
3-Hydroxypropionyl-CoA + Diphosphate + AMP <=> 3-Hydroxypropanoate + CoA + ATP
Aminohydroquinone + H2O <=> Benzene-1,2,4-triol + Ammonia
3-Nitrophenol + 2 NADH + 2 H+ <=> 3-Hydroxyaminophenol + 2 NAD+ + H2O
3-Hydroxypropanoate + NADP+ <=> 3-Oxopropanoate + NADPH + H+
UDP-D-xylose + G13051 <=> UDP + G03532
(2S)-Ethylmalonyl-CoA + NADP+ <=> Crotonoyl-CoA + CO2 + NADPH + H+
(2R)-Ethylmalonyl-CoA <=> (2S)-Methylsuccinyl-CoA
(2S)-Methylsuccinyl-CoA + Electron-transferring flavoprotein <=> 2-Methylfumaryl-CoA + Reduced electron-transferring flavoprotein
GDP-L-fucose + [Protein]-L-serine <=> GDP + G13052
UDP-N-acetyl-D-glucosamine + G13052 <=> UDP + G13053
CMP-N-acetylneuraminate + G13054 <=> CMP + G05914
CMP-N-acetylneuraminate + G13054 <=> CMP + G10982
UDP-D-galactose + G13053 <=> UDP + G13054
GDP-D-mannose + G13027 <=> GDP + G10737
GDP-D-mannose + G10737 <=> GDP + G10842
GDP-D-mannose + G10842 <=> GDP + G10843
GDP-D-mannose + G10843 <=> GDP + G11055
UDP-N-acetyl-D-glucosamine + [Protein]-L-serine <=> UDP + G12573
7,9,12-Octaketide intermediate 3 <=> Octaketide bicyclic intermediate + H2O
Octaketide bicyclic intermediate + NADPH + H+ <=> (S)-Chiral alcohol + NADP+
(S)-Chiral alcohol <=> (S)-Hemiketal
(S)-Hemiketal <=> (S)-DNPA + H2O
Octaketide bicyclic intermediate + NADPH + H+ <=> (R)-Chiral alcohol + NADP+
(R)-Chiral alcohol <=> (R)-Hemiketal
(R)-Hemiketal <=> (R)-DNPA + H2O
Dihydrokalafungin + NADH + H+ <=> Dihydrokalafungin dihydroquinone form + NAD+
Dihydrokalafungin dihydroquinone form + Reduced FMN + Oxygen <=> DHKred-OH + FMN + H2O
6-Deoxydihydrokalafungin + Reduced FMN + Oxygen <=> Dihydrokalafungin + FMN + H2O
UDP-D-glucose + [Protein]-L-serine <=> UDP + G13051
UDP-D-glucose + G13052 <=> UDP + G10981
Methyl-Co(III) corrinoid protein + CoA + CO2 + Reduced ferredoxin <=> Acetyl-CoA + Co(I) corrinoid protein + H2O + Oxidized ferredoxin
GDP-L-fucose + G00179 <=> GDP + G13056
GDP-L-fucose + G00014 <=> GDP + G10770
UDP-D-galactose + G10770 <=> UDP + G13057
Quinate + Quinone <=> 3-Dehydroquinate + Hydroquinone
G13057 + H2O <=> N-Acetyl-D-glucosamine + G13058
GDP-L-fucose + G13058 <=> GDP + G13059
7,9,12-Decaketide intermediate 3 <=> Deoxynogalonate
7,9,12-Decaketide intermediate 6 <=> 12-Deoxyaklanonic acid
Deoxynogalonate + Oxygen <=> Nogalonate + H2O
Methyl nogalonate <=> Nogalaviketone
Nogalaviketone + NADPH + H+ <=> Nogalavinone + NADP+
Nogalavinone <=> 1-OH-Nogalamycinone
Aklavinone + dTDP-beta-L-rhodosamine <=> Aclacinomycin T + dTDP
Aclacinomycin T + dTDP-2-deoxy-beta-L-fucose <=> Aclacinomycin S + dTDP
Aclacinomycin S <=> Aclacinomycin N
Aclacinomycin N + Oxygen <=> Aclacinomycin A + Hydrogen peroxide
Aclacinomycin A + Oxygen <=> Aclacinomycin Y + Hydrogen peroxide
epsilon-Rhodomycinone <=> epsilon-Rhodomycin T
epsilon-Rhodomycin T + H2O <=> 15-Demethoxy-epsilon-rhodomycin + Methanol
15-Demethoxy-epsilon-rhodomycin + Oxygen + 2 Glutathione <=> beta-Rhodomycin + CO2 + H2O + Glutathione disulfide
Methylmercury + H+ <=> Methane + Mercury(2+)
7,9,12-Decaketide intermediate 3 <=> UWM6
UWM6 <=> Rabelomycin
UWM6 <=> 2,3-Dehydro-UWM6 + H2O
2,3-Dehydro-UWM6 <=> Dehydrorabelomycin
2,3-Dehydro-UWM6 + L-Isoleucine <=> Jadomycin A + CO2 + H2O
UWM6 + dTDP-D-olivose <=> C1'-C9-Glycosylated UWM6 + dTDP
Rabelomycin <=> 11-Deoxylandomycinone
11-Deoxylandomycinone <=> Landomycin H
8-D-Olivosyl-landomycin <=> Landomycin D
Landomycin D <=> Landomycin E
7,12-Decaketide intermediate 1 <=> Decaketide tricyclic intermediate
Premithramycin A3 + dTDP-D-olivose <=> 3A-Deolivosylpremithramycin B + dTDP
3A-Deolivosylpremithramycin B + dTDP-D-olivose <=> Premithramycin B + dTDP
Premithramycin B + NADPH + H+ + Oxygen <=> Mithramycin DK + NADP+ + CO2
Mithramycin DK <=> Mithramycin
9,14-Decaketide intermediate 1 <=> Tetracenomycin F2 + Acyl-carrier protein
Landomycin H <=> 8-D-Olivosyl-landomycin
(2R)-2-Hydroxy-2-methylbutanenitrile <=> Methyl ethyl ketone + Hydrogen cyanide
(S)-Hydroxynitrile <=> Cyanide ion + Aldehyde
Landomycin E <=> Landomycin J
Landomycin J <=> Landomycin B
Landomycin B <=> Landomycin A
L-Arginine + 2-Oxoglutarate + Oxygen <=> beta-Hydroxyarginine + Succinate + CO2
beta-Hydroxyarginine <=> L-Capreomycidine + H2O
Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate
Se-Methyl-L-selenocysteine + H2O <=> Pyruvate + Ammonia + Methaneselenol
Selenite + 4 Glutathione + 2 H+ <=> Selenodiglutathione + Glutathione disulfide + 3 H2O
Selenodiglutathione + Glutathione <=> Glutathioselenol + Glutathione disulfide
S-Adenosyl-L-methionine + Methaneselenol <=> S-Adenosyl-L-homocysteine + Dimethyl selenide
S-Adenosyl-L-methionine + Dimethyl selenide <=> S-Adenosyl-L-homocysteine + Trimethylselenonium
S-Adenosyl-L-methionine + Hydrogen selenide <=> S-Adenosyl-L-homocysteine + Methaneselenol
2 NADPH + 2 H+ + Methylselenic acid <=> 2 NADP+ + 2 H2O + Methaneselenol
Se-Methyl-L-selenocysteine + 4-Methylthio-2-oxobutanoic acid <=> Methylselenopyruvate + L-Methionine
2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O <=> 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + Formate
2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NADH + H+ <=> 2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NAD+
2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NADPH + H+ <=> 2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NADP+
2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O <=> 5-Amino-6-(5'-phospho-D-ribitylamino)uracil + Ammonia
ATP + (R)-Pantoate <=> ADP + (R)-4-Phosphopantoate
ATP + (R)-4-Phosphopantoate + beta-Alanine <=> AMP + Diphosphate + D-4'-Phosphopantothenate
Acyl-[acyl-carrier protein] + sn-Glycerol 3-phosphate <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-carrier protein
Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate
tRNA precursor + 2 CTP + ATP <=> tRNA with a 3' CCA end + 3 Diphosphate
tRNA precursor + CTP <=> tRNA with a 3' cytidine + Diphosphate
tRNA with a 3' cytidine + CTP <=> tRNA with a 3' CC end + Diphosphate
(S)-Limonene + NADH + H+ + Oxygen <=> (4S)-Limonene-1,2-epoxide + NAD+ + H2O
tRNA with a 3' CC end + ATP <=> tRNA with a 3' CCA end + Diphosphate
(4S)-Limonene-1,2-epoxide + H2O <=> (1R,2R,4S)-Limonene-1,2-diol
(1R,2R,4S)-Limonene-1,2-diol + NAD+ <=> (1R,4S)-1-Hydroxy-2-oxolimonene + NADH + H+
(S)-Limonene + NADPH + Oxygen + H+ <=> (4S)-Limonene-1,2-epoxide + NADP+ + H2O
(1R,4S)-1-Hydroxy-2-oxolimonene + NADPH + Oxygen + H+ <=> (4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O
(4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone <=> (3S)-3-Isopropenyl-6-oxoheptanoate
(4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone <=> (3R)-3-Isopropenyl-6-oxoheptanoate
(R)-Limonene + NADPH + Oxygen + H+ <=> Limonene-1,2-epoxide + NADP+ + H2O
GTP + S-Adenosyl-L-methionine + Reduced acceptor <=> (8S)-3',8-Cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-Deoxyadenosine + L-Methionine + Acceptor
Precursor Z + 2 Thiocarboxy-[sulfur-carrier protein] <=> Molybdopterin + 2 Sulfur-carrier protein
(2S)-2-Phospholactate + GTP <=> (2S)-Lactyl-2-diphospho-5'-guanosine + Diphosphate
7,8-Didemethyl-8-hydroxy-5-deazariboflavin + (2S)-Lactyl-2-diphospho-5'-guanosine <=> Coenzyme F420-0 + GMP
Coenzyme F420-0 + GTP + L-Glutamate <=> Coenzyme F420-1 + GDP + Orthophosphate
Coenzyme F420-1 + GTP + L-Glutamate <=> Coenzyme F420 + GDP + Orthophosphate
ATP + Coenzyme F420 + L-Glutamate <=> ADP + Coenzyme F420-3 + Orthophosphate
Codeine + 2-Oxoglutarate + Oxygen <=> Morphine + Formaldehyde + Succinate + CO2
L-Isoleucine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-2-Methylbutanal oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin Q1 + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin M1 + H2O + NADP+
Aflatoxin M1 + Oxygen + NADPH + H+ <=> Aflatoxin-M1-8,9-epoxide + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin B1-endo-8,9-epoxide + H2O + NADP+
Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin B1-exo-8,9-epoxide + H2O + NADP+
Aflatoxin B1-exo-8,9-epoxide + Glutathione <=> Aflatoxin B1exo-8,9-epoxide-GSH
Aflatoxin B1-exo-8,9-epoxide + H2O <=> Aflatoxin B1 diol
Aflatoxin B1 diol <=> Aflatoxin B1 dialdehyde
Aflatoxin B1 dialdehyde <=> 1,2,3,4-Tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal
Aflatoxin B1 dialdehyde <=> alpha-(1,2-Dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde
1,2,3,4-Tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal <=> 6-[2,3-Dihydroxy-1-(hydroxymethyl)propyl]-1,2-dihydro-7-hydroxy-9-methoxy-cyclopenta[c][1]benzopyran-3,4-dione
alpha-(1,2-Dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde <=> 6-[2,3-Dihydroxy-1-(hydroxymethyl)propyl]-1,2-dihydro-7-hydroxy-9-methoxy-cyclopenta[c][1]benzopyran-3,4-dione
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene + H2O + NADP+
1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene + H2O <=> trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene
trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> (1aalpha,2beta,3alpha,11calpha)-1a,2,3,11c-Tetrahydro-6,11-dimethylbenzo[6,7]phenanthro[3,4-b]oxirene-2,3-diol + H2O + NADP+
Malonyl-CoA + Acyl-CoA <=> 3-Oxoacyl-CoA + CoA + CO2
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + NADPH + H+ <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + NADP+
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP+
Apoferritin + n Fe3+ <=> Ferritin
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + Oxygen + NADPH + H+ <=> 1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + Oxygen + NADPH + H+ <=> alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol + H2O + NADP+
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide + UDP
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> NNAL-N-glucuronide + UDP
UDP-glucuronate + Acceptor <=> UDP + Acceptor beta-D-glucuronoside
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone <=> 4-(Methylnitrosamino)-1-(1-oxido-3-pyridinyl)-1-butanone
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol <=> 4-(Methylnitrosamino)-1-(3-pyridyl-N-oxide)-1-butanol
4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone <=> 4-(Nitrosoamino)-1-(3-pyridinyl)-1-butanone + Formaldehyde
alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol <=> alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol + Formaldehyde
4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone <=> 4-Oxo-1-(3-pyridyl)-1-butanone + N-Nitrosomethanamine
1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol <=> 5-(3-Pyridyl)-2-hydroxytetrahydrofuran + N-Nitrosomethanamine
4-(Nitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O <=> 4-Hydroxy-1-(3-pyridinyl)-1-butanone + Nitrogen + H2O
alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol + H2O <=> 1-(3-Pyridinyl)-1,4-butanediol + Nitrogen + H2O
4-Hydroxy-1-(3-pyridinyl)-1-butanone <=> 3-Succinoylpyridine
5-(3-Pyridyl)-2-hydroxytetrahydrofuran <=> gamma-Hydroxy-3-pyridinebutanoate
1-(3-Pyridinyl)-1,4-butanediol <=> gamma-Hydroxy-3-pyridinebutanoate
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7-Hydroxymethyl-12-methylbenz[a]anthracene + H2O + NADP+
7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O + NADP+
7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O <=> trans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene
7-Hydroxymethyl-12-methylbenz[a]anthracene + 3'-Phosphoadenylyl sulfate <=> 7-Hydroxymethyl-12-methylbenz[a]anthracene sulfate + Adenosine 3',5'-bisphosphate
2 Nitric oxide + Menaquinol <=> Nitrous oxide + Menaquinone + H2O
2 Nitric oxide + NADPH + H+ <=> Nitrous oxide + NADP+ + H2O
D-Glucuronate + NAD+ + H2O <=> D-Glucarate + NADH + H+
16-Hydroxypalmitate <=> 16-Oxopalmitate
trans-2,3-Dehydroacyl-CoA + NADPH + H+ <=> Long-chain acyl-CoA + NADP+
Long-chain acyl-CoA + H2O <=> Long-chain fatty acid + CoA
Hexadecanoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16-Hydroxypalmitate + [Oxidized NADPH---hemoprotein reductase] + H2O
(9Z)-Octadecenoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 18-Hydroxyoleate + [Oxidized NADPH---hemoprotein reductase] + H2O
cis-9,10-Epoxystearic acid + NADPH + Oxygen + H+ <=> 9,10-Epoxy-18-hydroxystearate + NADP+ + H2O
Docosanoic acid + NADPH + Oxygen + H+ <=> 22-Hydroxydocosanoate + NADP+ + H2O
18-Hydroxyoleate <=> 18-Oxooleate
22-Hydroxydocosanoate <=> 22-Oxodocosanoate
16-Oxopalmitate <=> Hexadecanedioate
18-Oxooleate <=> Octadec-9-ene-1,18-dioic-acid
22-Oxodocosanoate <=> Docosanedioate
16-Hydroxypalmitate + NADPH + Oxygen + H+ <=> 10,16-Dihydroxyhexadecanoic acid + NADP+ + H2O
9,10-Dihydroxystearate + NADPH + Oxygen + H+ <=> 9,10,18-Trihydroxystearate + NADP+ + H2O
(9Z)-Octadecenoic acid + Lipid hydroperoxide <=> cis-9,10-Epoxystearic acid + Alcohol
18-Hydroxyoleate + Lipid hydroperoxide <=> 9,10-Epoxy-18-hydroxystearate + Alcohol
9,10-Epoxy-18-hydroxystearate + H2O <=> 9,10,18-Trihydroxystearate
cis-9,10-Epoxystearic acid + H2O <=> 9,10-Dihydroxystearate
Long-chain aldehyde <=> Alkane + CO
Alkane <=> Secondary alcohol
Secondary alcohol <=> Ketone
Ketone <=> Diketone
Long-chain acyl-CoA + 2 NADPH + 2 H+ <=> Primary alcohol + 2 NADP+ + CoA
6-Hydroxypseudooxynicotine + 2 H2O <=> 6-Hydroxy-3-succinoylpyridine + Methylamine
6-Hydroxy-3-succinoylpyridine + 2 NADH + 2 H+ + Oxygen <=> 2,5-Dihydroxypyridine + Succinate semialdehyde + 2 NAD+ + H2O
Nicotinate + H2O + 2 Ferricytochrome <=> 6-Hydroxynicotinate + 2 Ferrocytochrome + 2 H+
Long-chain acyl-CoA <=> Wax ester
ATP + Acetate + Acyl-carrier protein <=> AMP + Diphosphate + Acetyl-[acyl-carrier protein]
(S)-2,3-Epoxysqualene <=> Taraxerol
Xylitol + NAD+ <=> D-Xylose + NADH + H+
2-Hydroxyethylphosphonate + NAD+ <=> Phosphonoacetaldehyde + NADH + H+
Ethanol + Ubiquinone <=> Acetaldehyde + Ubiquinol
Primary alcohol + 2 Oxidized azurin <=> Aldehyde + 2 Reduced azurin + 2 H+
Formate + Oxidized hydrogenase <=> CO2 + Reduced hydrogenase
Malonyl-[acyl-carrier protein] <=> Acetyl-[acyl-carrier protein] + CO2
Malonate <=> Acetate + CO2
Long-chain aldehyde + Acyl-carrier protein + NAD+ <=> Long-chain acyl-[acyl-carrier protein] + NADH + H+
Long-chain aldehyde + Acyl-carrier protein + NADP+ <=> Long-chain acyl-[acyl-carrier protein] + NADPH + H+
Oxalate + 2 Oxidized ferredoxin <=> 2 CO2 + 2 Reduced ferredoxin + 2 H+
(1E,4S,5E,7R)-Germacra-1(10),5-dien-11-ol + H2O <=> Geosmin + Acetone
Indole-3-carboxylate <=> Indole + CO2
Protoporphyrinogen IX + 3 Quinone <=> Protoporphyrin + 3 Hydroquinone
(3Z)-Phycoerythrobilin + 2 Oxidized ferredoxin <=> Biliverdin + 2 Reduced ferredoxin
2 Menaquinol + Oxygen + n H+ <=> 2 Menaquinone + 2 H2O + n H+
D-Amino acid + H2O + Quinone <=> 2-Oxo acid + Ammonia + Hydroquinone
Formate + Quinone <=> CO2 + Hydroquinone
N6-(L-1,3-Dicarboxypropyl)-L-lysine + H2O + Oxygen <=> L-2-Aminoadipate 6-semialdehyde + L-Glutamate + Hydrogen peroxide
D-Proline + Acceptor <=> 1-Pyrroline-2-carboxylate + Reduced acceptor
Nitrate + Hydroquinone <=> Nitrite + Quinone + H2O
Dimethyl sulfoxide + H2O + NAD+ <=> Dimethyl sulfone + NADH + H+
Hydrogen sulfide + 2 Ferricytochrome c <=> Sulfur + 2 Ferrocytochrome c + 2 H+
Dimethyl sulfide + 2 Ferricytochrome c2 + H2O <=> Dimethyl sulfoxide + 2 Ferrocytochrome c2 + 2 H+
Dimethyl sulfide + Menaquinone + H2O <=> Dimethyl sulfoxide + Menaquinol
2 Reduced ferredoxin + Thioredoxin disulfide <=> 2 Oxidized ferredoxin + Thioredoxin + 2 H+
2 H2O + 2 Plastoquinone + 4 hn <=> Oxygen + 2 Plastoquinol
2 Ubiquinol + Oxygen <=> 2 Ubiquinone + 2 H2O
Alkane + Hydrobromic acid + Hydrogen peroxide <=> RBr + 2 H2O
Thioredoxin + Prostaglandin H2 <=> Thioredoxin disulfide + Prostaglandin F2alpha
Alkane + Hydrogen peroxide <=> ROH + H2O
2 Hydrogen + NAD+ + 2 Oxidized ferredoxin <=> 5 H+ + NADH + 2 Reduced ferredoxin
Carboxybiotinyl-[protein] + H+ <=> Biotinyl-[protein] + CO2
Protein N6,N6-dimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein N6-methyl-L-lysine + Succinate + Formaldehyde + CO2
Protein N6-methyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein lysine + Succinate + Formaldehyde + CO2
Carbazole + NADPH + H+ + Oxygen <=> 2'-Aminobiphenyl-2,3-diol + NADP+
Methanesulfonic acid + NADH + H+ + Oxygen <=> Formaldehyde + NAD+ + Sulfite + H2O
Urate + NADH + H+ + Oxygen <=> 5-Hydroxyisourate + NAD+ + H2O
Calcitriol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitetrol + 2 Oxidized adrenal ferredoxin + H2O
Calcidiol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Secalciferol + 2 Oxidized adrenal ferredoxin + H2O
Anthranilate + FADH2 + Oxygen <=> 3-Hydroxyanthranilate + FAD + H2O
Methane + Hydroquinone + Oxygen <=> Methanol + Quinone + H2O
Ammonia + Reduced acceptor + Oxygen <=> Hydroxylamine + Acceptor + H2O
FAD + NADPH + H+ <=> FADH2 + NADP+
L-Tyrosine + NADP+ + Iodide <=> 3-Iodo-L-tyrosine + NADPH
3-Iodo-L-tyrosine + NADP+ + Iodide <=> 3,5-Diiodo-L-tyrosine + NADPH
S-Adenosyl-L-methionine + Iodide + H+ <=> S-Adenosyl-L-homocysteine + Methyl iodide
Acetoin + CoA + NAD+ <=> Acetaldehyde + Acetyl-CoA + NADH + H+
trans,trans-Farnesyl diphosphate <=> Zingiberene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> beta-Eudesmol + Diphosphate
Acetyl-CoA + Malonyl-CoA <=> Acetoacetyl-CoA + CoA + CO2
Benzoyl-CoA + Benzyl alcohol <=> Benzyl benzoate + CoA
UDP-glucuronate + Baicalein <=> UDP + Baicalin
O-Phospho-L-serine + Sulfite <=> L-Cysteate + Orthophosphate
S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + Thermospermine + H+
2,3-Bisphospho-D-glycerate + H2O <=> 2-Phospho-D-glycerate + Orthophosphate
Baicalin + H2O <=> Baicalein + D-Glucuronate
Hesperidin + H2O <=> Hesperetin + Rutinose
Angiotensin II + H2O <=> Angiotensin (1-7) + L-Phenylalanine
Anandamide + H2O <=> Arachidonate + Ethanolamine
Oleamide + H2O <=> (9Z)-Octadecenoic acid + Ammonia
CDP-choline + H2O <=> CMP + Choline phosphate
Salicylate <=> Phenol + CO2
2 Ascorbate + Hydrogen peroxide <=> 2 Monodehydroascorbate + 2 H2O
2 Fe2+ + NADP+ + H+ <=> 2 Fe3+ + NADPH
Reduced plastocyanin + Oxidized ferredoxin + hn <=> Oxidized plastocyanin + Reduced ferredoxin
S-Adenosyl-L-methionine + Malonyl-[acyl-carrier protein] <=> S-Adenosyl-L-homocysteine + Malonyl-[acp] methyl ester
D-Arabinitol 1-phosphate + NAD+ <=> D-Xylulose 5-phosphate + NADH + H+
(R)-2,3-Dihydroxypropane-1-sulfonate + 2 NAD+ + H2O <=> (2R)-3-Sulfolactate + 2 NADH + 2 H+
Germacra-1(10),4,11(13)-trien-12-ol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Germacrene A acid + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
(+)-Germacrene A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Germacra-1(10),4,11(13)-trien-12-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
D-Glucose 6-phosphate + Coenzyme F420 <=> D-Glucono-1,5-lactone 6-phosphate + Reduced coenzyme F420
L-Sorbose + Acceptor <=> L-Sorbosone + Reduced acceptor
Ethanol + N,N-Dimethyl-4-nitrosoaniline <=> Acetaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline
Methanol + N,N-Dimethyl-4-nitrosoaniline <=> Formaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline
3,4-Didehydroadipyl-CoA semialdehyde + NADP+ + H2O <=> 3,4-Didehydroadipyl-CoA + NADPH + H+
Benzoyl-CoA + NADPH + H+ + Oxygen <=> 2,3-Epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O
2,3-Epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O <=> 3,4-Didehydroadipyl-CoA semialdehyde + Formate
Sulfoacetaldehyde + CoA + NADP+ <=> Sulfoacetyl-CoA + NADPH + H+
trans,trans-Farnesyl diphosphate <=> (+)-Germacrene D + Diphosphate
2-Amino-2-deoxyisochorismate + FMN <=> 3-(1-Carboxyvinyloxy)anthranilate + Reduced FMN
7-Chloro-L-tryptophan + Oxygen <=> 2-Imino-3-(7-chloroindol-3-yl)propanoate + Hydrogen peroxide
2 Glutathione amide + NAD+ <=> Glutathione amide disulfide + NADH + H+
Farnesylcysteine + Oxygen + H2O <=> 2-trans,6-trans-Farnesal + L-Cysteine + Hydrogen peroxide
2 Glutathione amide + Hydrogen peroxide <=> Glutathione amide disulfide + 2 H2O
Cl- + Hydrogen peroxide + H+ <=> Hypochlorous acid + H2O
Gallate + Oxygen <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
4 2-Imino-3-(7-chloroindol-3-yl)propanoate + Oxygen <=> 2 3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 2 Ammonia + 2 H2O
3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 4 Oxygen + 4 NADH + 4 H+ <=> Dichloroarcyriaflavin A + 2 CO2 + 6 H2O + 4 NAD+
4'-O-Demethylrebeccamycin + H2O <=> Dichloroarcyriaflavin A + beta-D-Glucose
4'-O-Demethylrebeccamycin + S-Adenosyl-L-methionine <=> Rebeccamycin + S-Adenosyl-L-homocysteine
L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 7-Chloro-L-tryptophan + FAD + 2 H2O
Dinoflagellate luciferin + Oxygen <=> Oxidized dinoflagellate luciferin + H2O + hn
L-Proline + 2-Oxoglutarate + Oxygen <=> cis-3-Hydroxy-L-proline + Succinate + CO2
5-Epiaristolochene + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Capsidiol + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
trans,trans-Farnesyl diphosphate <=> 5-Epiaristolochene + Diphosphate
Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Costunolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Vetispiradiene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Solavetivol + [Oxidized NADPH---hemoprotein reductase] + H2O
Solavetivol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Solavetivone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
L-Phenylalanine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-Phenylacetaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
L-Phenylalanine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-phenylalanine + [Oxidized NADPH---hemoprotein reductase] + H2O
N-Hydroxy-L-phenylalanine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-phenylalanine + [Oxidized NADPH---hemoprotein reductase] + H2O
N,N-Dihydroxy-L-phenylalanine <=> (E)-Phenylacetaldoxime + CO2 + H2O
L-Tryptophan + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N-Hydroxy-L-tryptophan + [Oxidized NADPH---hemoprotein reductase] + H2O
N-Hydroxy-L-tryptophan + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N,N-Dihydroxy-L-tryptophan + [Oxidized NADPH---hemoprotein reductase] + H2O
N,N-Dihydroxy-L-tryptophan <=> Indole-3-acetaldehyde oxime + CO2 + H2O
Pyrrole-2-carboxylate + NADH + H+ + Oxygen <=> 5-Hydroxypyrrole-2-carboxylate + NAD+ + H2O
Progesterone + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> 15beta-Hydroxyprogesterone + 2 Oxidized [2Fe-2S] ferredoxin + H2O
D-Alanine + (R)-Lactate + ATP <=> D-Alanyl-(R)-lactate + ADP + Orthophosphate
ATP + 3-Hydroxybenzoate + CoA <=> AMP + Diphosphate + 3-Hydroxybenzoyl-CoA
ATP + D-Aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n <=> [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + Orthophosphate
1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-Cysteine + ATP <=> 1-O-[2-(L-Cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + AMP + Diphosphate
ATP + [L-Asp(4-L-Arg)]n + L-Aspartate <=> ADP + Orthophosphate + [L-Asp(4-L-Arg)]n-L-Asp
ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-Arginine <=> ADP + Orthophosphate + [L-Asp(4-L-Arg)]n+1
ATP + 5,6,7,8-Tetrahydromethanopterin + L-Glutamate <=> ADP + Orthophosphate + Tetrahydrosarcinapterin
D-Alanine + D-Serine + ATP <=> D-Alanyl-D-serine + ADP + Orthophosphate
ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-Lysine <=> ADP + Orthophosphate + N6-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl)-D-lysine
[tRNA(Ile2)]-cytidine34 + L-Lysine + ATP <=> [tRNA(Ile2)]-lysidine34 + AMP + Diphosphate + H2O
Cobyrinate + L-Glutamine + ATP + H2O <=> Cobyrinate c-monamide + L-Glutamate + ADP + Orthophosphate
Cobyrinate c-monamide + L-Glutamine + ATP + H2O <=> Cob(II)yrinate a,c diamide + L-Glutamate + ADP + Orthophosphate
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate <=> UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate
all-trans-8'-Apo-beta-carotenal + Oxygen <=> Retinal + (2E,4E,6E)-2,6-Dimethylocta-2,4,6-trienedial
Pratensein + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-Hydroxypseudobaptigenin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Zeaxanthin + 2 Oxygen <=> Crocetin dialdehyde + 2 (3S)-3-Hydroxycyclocitral
beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 24-Hydroxy-beta-amyrin + [Oxidized NADPH---hemoprotein reductase] + H2O
Sophoradiol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Soyasapogenol B + [Oxidized NADPH---hemoprotein reductase] + H2O
trans,trans-Farnesyl diphosphate <=> (-)-alpha-Gurjunene + Diphosphate
(2Z,6Z)-Farnesyl diphosphate <=> (-)-endo-alpha-Bergamotene + Diphosphate
(2Z,6Z)-Farnesyl diphosphate <=> (+)-alpha-Santalene + Diphosphate
(2Z,6Z)-Farnesyl diphosphate <=> (+)-endo-beta-Bergamotene + Diphosphate
2-cis,6-trans-Farnesyl diphosphate <=> (-)-gamma-Cadinene + Diphosphate
2 S-Adenosyl-L-methionine + Tricetin <=> 2 S-Adenosyl-L-homocysteine + Tricin
S-Adenosyl-L-methionine + Tricetin <=> S-Adenosyl-L-homocysteine + 3'-O-Methyltricetin
S-Adenosyl-L-methionine + 3'-O-Methyltricetin <=> S-Adenosyl-L-homocysteine + Tricin
trans,trans-Farnesyl diphosphate <=> (+)-alpha-Barbatene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Cubenene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-delta-Selinene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-Epicubenol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (3R,6E)-Nerolidol + Diphosphate
trans,trans-Farnesyl diphosphate <=> (E)-gamma-Bisabolene + Diphosphate
trans,trans-Farnesyl diphosphate <=> gamma-Bisabolene + Diphosphate
3 Malonyl-CoA + Benzoyl-CoA <=> 4 CoA + 3,5-Dihydroxybiphenyl + 4 CO2
1-O-[2-(L-Cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + Acetyl-CoA <=> Mycothiol + CoA
trans,trans-Farnesyl diphosphate <=> (S)-beta-Bisabolene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Germacrene C + Diphosphate
(S)-beta-Bisabolene <=> (S)-beta-Macrocarpene
trans,trans-Farnesyl diphosphate <=> cis-Muurola-3,5-diene + Diphosphate
trans,trans-Farnesyl diphosphate <=> cis-Muurola-4(14),5-diene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (-)-Drimenol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Patchoulol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Presilphiperfolan-8beta-ol + Diphosphate
Acetyl-CoA + 3-Hexenol <=> (Z)-3-Hexen-1-ol acetate + CoA
beta-D-Galactosyl-(1->4)-L-rhamnose + Orthophosphate <=> L-Rhamnose + alpha-D-Galactose 1-phosphate
Dimethylallyl diphosphate + 2 Isopentenyl diphosphate <=> 2 Diphosphate + (2Z,6Z)-Farnesyl diphosphate
UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-Inositol 3-phosphate <=> 1-O-(2-Acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + UDP
UDP-glucuronate + Chrysanthemin <=> UDP + Cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside
UDP-glucuronate + Soyasapogenol B <=> UDP + Soyasapogenol B 3-O-D-glucuronide
S-Adenosyl-L-methionine + Fluoride <=> 5'-Deoxy-5'-fluoroadenosine + L-Methionine
Dimethylallyl diphosphate + L-Tryptophan <=> Diphosphate + 7-(3-Methylbut-2-enyl)-L-tryptophan
S-Adenosyl-L-methionine + Cl- <=> 5-Deoxy-5-chloroadenosine + L-Methionine
ATP + 1,6-Anhydro-N-acetyl-beta-muramate + H2O <=> ADP + N-Acetyl-beta-muramate 6-phosphate
UDP-glucose + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + alpha-D-Glucopyranosyl-diphospho-ditrans,octacis-undecaprenol
UDP-D-xylose + 3-O-alpha-D-Mannopyranosyl-alpha-D-mannopyranose <=> UMP + 3-O-(6-O-alpha-D-Xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose
Fluoroacetyl-CoA + H2O <=> Fluoroacetate + CoA
1,2-Diacyl-sn-glycerol 3-diphosphate + H2O <=> Phosphatidate + Orthophosphate
N-Acyl-L-homoserine lactone + H2O <=> L-Homoserine lactone + Carboxylate
(R)-Piperazine-2-carboxamide + H2O <=> (R)-Piperazine-2-carboxylate + Ammonia
beta-Alaninamide + H2O <=> beta-Alanine + Ammonia
(S)-Piperazine-2-carboxamide + H2O <=> (S)-Piperazine-2-carboxylate + Ammonia
L-Prolinamide + H2O <=> L-Proline + Ammonia
1-O-[2-(Acetylamino)-2-deoxy-alpha-D-glucopyranosyl]-D-myo-Inositol + H2O <=> 1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + Acetate
15-cis-Phytoene + 2 Plastoquinone <=> 9,15,9'-tricis-zeta-Carotene + 2 Plastoquinol
15-cis-Phytoene + Plastoquinone <=> 15,9'-dicis-Phytofluene + Plastoquinol
15,9'-dicis-Phytofluene + Plastoquinone <=> 9,15,9'-tricis-zeta-Carotene + Plastoquinol
9,15,9'-tricis-zeta-Carotene <=> 9,9'-dicis-zeta-Carotene
9,9'-dicis-zeta-Carotene + Quinone <=> 7,9,9'-tricis-Neurosporene + Hydroquinone
Streptothricin F + H2O <=> Streptothricin F acid
7,9,9'-tricis-Neurosporene + Quinone <=> 7,9,7',9'-tetracis-Lycopene + Hydroquinone
all-trans-zeta-Carotene + 2 Acceptor <=> Lycopene + 2 Reduced acceptor
5'-Methylthioadenosine + H2O <=> 5'-S-Methyl-5'-thioinosine + Ammonia
5-Nitroanthranilate + H2O <=> 5-Nitrosalicylate + Ammonia
Reduced flavin + NAD+ <=> Flavin + NADH + H+
NDP-glucose + 3-Phospho-D-glycerate <=> NDP + 2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate
2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate + H2O <=> 2-O-(alpha-D-Glucopyranosyl)-D-glycerate + Orthophosphate
ADP-glucose + D-Glycerate <=> 2-O-(alpha-D-Glucopyranosyl)-D-glycerate + ADP
GDP-mannose + D-Glycerate <=> GDP + 2-O-(alpha-D-Mannosyl)-D-glycerate
GDP-mannose + 2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate <=> GDP + 2-O-[2-O-(alpha-D-Mannopyranosyl)-alpha-D-glucopyranosyl]-3-phospho-D-glycerate
5'-S-Methyl-5'-thioinosine + Orthophosphate <=> Hypoxanthine + S-Methyl-5-thio-D-ribose 1-phosphate
CTP + 1D-myo-Inositol 3-phosphate <=> Diphosphate + CDP-1L-myo-inositol
CDP-1L-myo-inositol + 1D-myo-Inositol 3-phosphate <=> CMP + Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
4,4'-Diapolycopene + 4 Reduced acceptor + 4 Oxygen <=> 4,4'-Diapolycopenedial + 4 Acceptor + 6 H2O
[Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine + H2O <=> [Protein]-L-serine + N-Acetyl-D-glucosamine
[Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine + H2O <=> [Protein]-L-threonine + N-Acetyl-D-glucosamine
Fumonisin B1 + 2 H2O <=> Aminopentol + 2 Propane-1,2,3-tricarboxylate
ATP + Dephospho-CoA <=> 2'-(5-Triphosphoribosyl)-3'-dephospho-CoA + Adenine
UDP-N-acetyl-alpha-D-glucosamine + [Protein]-L-serine <=> UDP + [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine
UDP-N-acetyl-alpha-D-glucosamine + [Protein]-L-threonine <=> UDP + [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine
S-Adenosyl-L-methionine + Tricin <=> S-Adenosyl-L-homocysteine + 3',4',5'-O-Trimethyltricetin
3 S-Adenosyl-L-methionine + Tricetin <=> 3 S-Adenosyl-L-homocysteine + 3',4',5'-O-Trimethyltricetin
(S)-Piperidine-2-carboxamide + H2O <=> L-Pipecolate + Ammonia
ent-Copalyl diphosphate <=> ent-Pimara-9(11),15-diene + Diphosphate
9-cis-Epoxycarotenoid + Oxygen <=> Xanthoxin + 12'-apo-Carotenal
threo-3-Hydroxy-D-aspartate <=> Oxaloacetate + Ammonia
Terpentedienyl diphosphate <=> Terpentetriene + Diphosphate
Geranylgeranyl diphosphate <=> Elisabethatriene + Diphosphate
Copalyl diphosphate + H2O <=> Phyllocladan-16alpha-ol + Diphosphate
Neryl diphosphate <=> beta-Phellandrene + Diphosphate
(S)-2,3-Epoxysqualene <=> Cucurbitadienol
(S)-2,3-Epoxysqualene <=> Protostadienol
4,4'-Diapophytoene + 4 FAD <=> 4,4'-Diapolycopene + 4 FADH2
15-cis-Phytoene + 3 Acceptor <=> all-trans-Neurosporene + 3 Reduced acceptor
15-cis-Phytoene + Acceptor <=> all-trans-Phytofluene + Reduced acceptor
15-cis-Phytoene + 2 Acceptor <=> all-trans-zeta-Carotene + 2 Reduced acceptor
1,5-Anhydro-D-fructose <=> 1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose <=> 2-Hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one
1,5-Anhydro-D-fructose <=> 2-Hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O
UDP-N-acetyl-alpha-D-glucosamine <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + H2O
(3R)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA + H2O
9(S)-HPODE <=> Colneleate + H2O
Arabidiol <=> (S)-2,3-Epoxysqualene + H2O
Dammarenediol II <=> (S)-2,3-Epoxysqualene + H2O
(+)-Linalool <=> Myrcene + H2O
15-cis-Phytoene + 5 Acceptor <=> 3,4-Dehydrolycopene + 5 Reduced acceptor
D-5-Monosubstituted hydantoin <=> L-5-Monosubstituted hydantoin
1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose <=> 1,5-Anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose
(5S,6S)-6-Amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate <=> (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate
Geraniol <=> (+)-Linalool
(S)-2,3-Epoxysqualene <=> Thalianol
(S)-2,3-Epoxysqualene <=> Germanicol
(S)-2,3-Epoxysqualene <=> Isomultiflorenol
Squalene <=> Dammara-20,24-diene
(S)-2,3-Epoxysqualene <=> Camelliol C
Geranylgeranyl diphosphate <=> Terpentedienyl diphosphate
Geranylgeranyl diphosphate <=> Halima-5(6),13-dien-15-yl diphosphate
15-cis-Phytoene + 4 Acceptor <=> Lycopene + 4 Reduced acceptor
threo-3-Hydroxy-D-aspartate <=> Glycine + Glyoxylate
D-erythro-3-Hydroxyaspartate <=> Glycine + Glyoxylate
4,4'-Diapophytoene + FAD <=> 4,4'-Diapophytofluene + FADH2
(R)-2-Hydroxybutane-1,2,4-tricarboxylate <=> Homoisocitrate
Peptidoglycan(N-acetyl-D-glucosamine) + n H2O <=> Peptidoglycan-D-glucosamine + n Acetate
[L-Asp(4-L-Arg)]n+1(n) + H2O <=> [L-Asp(4-L-Arg)]n(n-1) + L-Asp(4-L-Arg)
Abscisic acid glucose ester + H2O <=> D-Glucose + Abscisate
trans-Permethrin + H2O <=> (3-Phenoxyphenyl)methanol + (1S,3R)-3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
Pimeloyl-[acyl-carrier protein] methyl ester + H2O <=> Pimeloyl-[acyl-carrier protein] + Methanol
ATP + Molybdopterin <=> Diphosphate + Adenylated molybdopterin
4,4'-Diaponeurosporene + 2 Reduced acceptor + 2 Oxygen <=> 4,4'-Diaponeurosporen-4-al + 2 Acceptor + 3 H2O
4,4'-Diaponeurosporen-4-al + Reduced acceptor + Oxygen <=> 4,4'-Diaponeurosporenic acid + Acceptor + H2O
ATP + Hygromycin B <=> ADP + 4-O-Phosphohygromycin B
Geranylgeranyl diphosphate + 7 Isopentenyl diphosphate <=> 7 Diphosphate + tritrans,heptacis-Undecaprenyl diphosphate
2-cis,6-trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> n Diphosphate + trans,polycis-Polyprenyl diphosphate
UDP-glucuronate + D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> UDP + D-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol
GDP-mannose + D-Glc-beta-(1->4)-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> GDP + D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol
GDP-mannose + D-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> GDP + D-Man-beta-(1->4)-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol
Adenylated molybdopterin + Molybdate <=> Molybdoenzyme molybdenum cofactor + AMP + H2O
Demethylmenaquinol + S-Adenosyl-L-methionine <=> Menaquinol + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + 2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol <=> S-Adenosyl-L-homocysteine + 6-Methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol
Butanoyl-CoA + NADP+ <=> Crotonoyl-CoA + NADPH + H+
Ascorbate + Fe3+ <=> Monodehydroascorbate + Fe2+
Fatty acid + Hydrogen peroxide <=> alpha-Hydroxy fatty acid + H2O
Fatty acid + Hydrogen peroxide <=> 3-Hydroxy fatty acid + H2O
Cyclic alcohol + Quinone <=> Cyclic ketone + Hydroquinone
Lupan-3beta,20-diol <=> (S)-2,3-Epoxysqualene + H2O
4,4'-Diapophytofluene + FAD <=> 4,4'-Diapo-zeta-carotene + FADH2
4,4'-Diapo-zeta-carotene + FAD <=> 4,4'-Diaponeurosporene + FADH2
4,4'-Diaponeurosporene + FAD <=> 4,4'-Diapolycopene + FADH2
beta-Carotene + 4 Reduced ferredoxin + 2 H+ + 2 Oxygen <=> Zeaxanthin + 4 Oxidized ferredoxin + 2 H2O
FADH2 + NAD+ <=> FAD + NADH + H+
Reduced coenzyme F420 + NADP+ <=> Coenzyme F420 + NADPH + H+
Reduced riboflavin + NAD+ <=> Riboflavin + NADH + H+
3 Nitrite <=> 2 Nitric oxide + Nitrate + H2O
GDP-glucose + Orthophosphate <=> D-Glucose 1-phosphate + GDP
UDP-alpha-D-galactose + Soyasapogenol B 3-O-D-glucuronide <=> UDP + Soyasaponin III
UDP-L-rhamnose + Soyasaponin III <=> UDP + Soyasaponin I
UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
Versicolorone + NADP+ <=> 1'-Hydroxyversicolorone + NADPH + H+
UDP-glucose + Crocetin <=> UDP + beta-D-Glucosyl crocetin
UDP-glucose + beta-D-Glucosyl crocetin <=> UDP + Bis(beta-D-glucosyl) crocetin
UDP-glucose + beta-D-Gentiobiosyl crocetin <=> UDP + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester
Phosphoenolpyruvate + D-Man-beta-(1->4)-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> 4,6-CH3(COO-)C-D-Man-beta-(1->4)-D-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol + Orthophosphate
Castasterone <=> 26-Hydroxycastasterone
Brassinolide <=> 26-Hydroxybrassinolide
KDO2-lipid IVA + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP
Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP
alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP
alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP
3-Deoxy-D-manno-octulosonyl-lipid IV(A) + ATP <=> 4-O-Phospho-alpha-Kdo-(2->6)-lipid IVA + ADP
Sedoheptulose 7-phosphate <=> D-glycero-D-manno-Heptose 7-phosphate
Sedoheptulose 7-phosphate <=> D-glycero-alpha-D-manno-Heptose 7-phosphate
D-glycero-alpha-D-manno-Heptose 7-phosphate + ATP <=> D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate + ADP
D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate + H2O <=> D-glycero-alpha-D-manno-Heptose 1-phosphate + Orthophosphate
D-glycero-alpha-D-manno-Heptose 1-phosphate + GTP <=> GDP-D-glycero-alpha-D-manno-heptose + Diphosphate
Undecaprenyl phosphate alpha-L-Ara4N + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate <=> Lipid IIA + di-trans,poly-cis-Undecaprenyl phosphate
Undecaprenyl phosphate alpha-L-Ara4N + KDO2-lipid IVA <=> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-lipid IVA + di-trans,poly-cis-Undecaprenyl phosphate
L-2-Aminoadipate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-gamma-L-alpha-aminoadipate + ADP + Orthophosphate
LysW-gamma-L-alpha-aminoadipate + ATP <=> LysW-gamma-L-alpha-aminoadipyl 6-phosphate + ADP
LysW-gamma-L-alpha-aminoadipyl 6-phosphate + NADPH + H+ <=> LysW-gamma-L-alpha-aminoadipate 6-semialdehyde + NADP+ + Orthophosphate
LysW-gamma-L-alpha-aminoadipate 6-semialdehyde + L-Glutamate <=> LysW-gamma-L-lysine + 2-Oxoglutarate
LysW-gamma-L-lysine + H2O <=> L-Lysine + alpha-Aminoadipate carrier protein LysW
D-arabino-Hex-3-ulose 6-phosphate <=> beta-D-Fructose 6-phosphate
KDO2-lipid A + Undecaprenyl phosphate alpha-L-Ara4N <=> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-lipid A + di-trans,poly-cis-Undecaprenyl phosphate
Torulene + Oxygen <=> 4'-Apo-beta,psi-caroten-4'-al + 3-Methyl-2-butenal
4'-Apo-beta,psi-caroten-4'-al + NAD+ + H2O <=> Neurosporaxanthin + NADH + H+
2-Oxoglutarate + Oxygen <=> Ethylene + 3 CO2 + H2O
2-Oxoglutarate + L-Arginine + Oxygen <=> Succinate + CO2 + Guanidine + (S)-1-Pyrroline-5-carboxylate + H2O
Dimethyl sulfide + Oxygen + NADH + H+ <=> Methanethiol + Formaldehyde + NAD+ + H2O
Arsenite + H2O + 2 Ferricytochrome c <=> Arsenate ion + 2 Ferrocytochrome c + 2 H+
trans,trans-Farnesyl diphosphate + H2O <=> alpha-Eudesmol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-gamma-Eudesmol + Diphosphate
1,1'-Dihydroxy-1,1',2,2'-tetrahydrolycopene <=> 1-Hydroxy-1,2-dihydrolycopene + H2O
S-Adenosyl-L-methionine + Naringenin <=> S-Adenosyl-L-homocysteine + Sakuranetin
S-Adenosyl-L-methionine + 4'-Hydroxyflavanone <=> S-Adenosyl-L-homocysteine + 4'-Methoxyflavanone
Presqualene diphosphate <=> 4,4'-Diapophytoene + Diphosphate
Pyrrole-2-carboxylate <=> Pyrrole + CO2
Pyrrole-2-carboxylate + H2O <=> Pyrrole + HCO3-
(R)-Lactate <=> Methylglyoxal + H2O
N-Acetyl-alpha-neuraminate <=> N-Acetyl-beta-neuraminate
Nitrilotriacetic acid + Reduced FMN + Oxygen <=> Iminodiacetate + Glyoxylate + FMN + H2O
Nitric oxide + Ammonia + 3 Ferrocytochrome c <=> Hydrazine + H2O + 3 Ferricytochrome c
Ectoine + H2O <=> N(alpha)-Acetyl-L-2,4-diaminobutyrate
N(alpha)-Acetyl-L-2,4-diaminobutyrate + H2O <=> L-2,4-Diaminobutanoate + Acetate
Kaempferol + UDP-L-rhamnose <=> Afzelin + UDP
Quercetin + UDP-L-rhamnose <=> Quercitrin + UDP
Quercitrin + UDP-glucose <=> Quercetin 3-O-rhamnoside 7-O-glucoside + UDP
L-Aspartate 4-semialdehyde + NAD+ + H2O <=> L-Aspartate + NADH + H+
Raucaffrinoline + NADP+ <=> Perakine + NADPH + H+
Prosolanapyrone II + Oxygen <=> Prosolanapyrone III + Hydrogen peroxide
Nitric oxide + Azide <=> Nitrous oxide + Nitrogen
Nitric oxide + Ammonia <=> Nitrous oxide + H2O
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> (9R,10E,12Z,15Z)-9-Hydroperoxyoctadeca-10,12,15-trienoate
Linoleate + Oxygen <=> (8E,10R,12Z)-10-Hydroperoxy-8,12-octadecadienoate
Pentalenene + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Pentalen-13-ol + 2 Oxidized ferredoxin + H2O
Pentalen-13-ol + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Pentalen-13-al + 2 Oxidized ferredoxin + 2 H2O
Pentalenene + 4 Reduced ferredoxin + 4 H+ + 2 Oxygen <=> Pentalen-13-al + 4 Oxidized ferredoxin + 3 H2O
beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11alpha-Hydroxy-beta-amyrin + H2O + [Oxidized NADPH---hemoprotein reductase]
11alpha-Hydroxy-beta-amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Oxo-beta-amyrin + 2 H2O + [Oxidized NADPH---hemoprotein reductase]
beta-Amyrin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 11-Oxo-beta-amyrin + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase]
1-Hydroxy-2-naphthoate + NADPH + H+ + Oxygen <=> Naphthalene-1,2-diol + NADP+ + H2O + CO2
3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + Reduced FMN + Oxygen <=> 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O
3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP+ + H2O <=> 3-Oxo-5,6-dehydrosuberyl-CoA + NADPH + H+
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-methionine <=> dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-homocysteine
Mycinamicin VI + S-Adenosyl-L-methionine <=> Mycinamicin III + S-Adenosyl-L-homocysteine
Mycinamicin III + S-Adenosyl-L-methionine <=> Mycinamicin IV + S-Adenosyl-L-homocysteine
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-Oxoglutarate <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-Glutamate
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-Oxoglutarate <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate
Retinyl ester + H2O <=> 13-cis-Retinol + Fatty acid
Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + Orthophosphate
L-Tyrosine + H2O + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + Ammonia + NADH + H+
beta-D-4-Deoxy-Delta4-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O <=> 5-Dehydro-4-deoxy-D-glucuronate + beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc
8-Oxo-dGTP + H2O <=> 8-Oxo-dGMP + Diphosphate
2-Hydroxy-dATP + H2O <=> 2-Hydroxy-dAMP + Diphosphate
UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + H2O <=> 2,4-Bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + UDP
(+)-beta-Caryophyllene + H2O <=> (+)-Caryolan-1-ol
2-Oxepin-2(3H)-ylideneacetyl-CoA + H2O <=> 3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde
2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA <=> 2-Oxepin-2(3H)-ylideneacetyl-CoA
Phenylacetyl-CoA + Oxygen + NADPH + H+ <=> 2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+
3-Oxo-5,6-dehydrosuberyl-CoA + CoA <=> 5-Carboxy-2-pentenoyl-CoA + Acetyl-CoA
Phenylacetyl-CoA + H2O <=> Phenylacetic acid + CoA
2,4-Bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + Phosphoenolpyruvate + H2O <=> Pseudaminic acid + Orthophosphate
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + Acetyl-CoA <=> UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + CoA
Pseudaminic acid + CTP <=> CMP-pseudaminic acid + Diphosphate
trans,trans-Farnesyl diphosphate + Protein-cysteine <=> S-Farnesyl protein + Diphosphate
S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide
Protein C-terminal S-farnesyl-L-cysteine + Methanol <=> Protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O
Protein C-terminal S-farnesyl-L-cysteine methyl ester <=> Farnesylcysteine
2-trans,6-trans-Farnesal <=> (2E,6E)-Farnesol
(2E,6E)-Farnesol + CTP <=> trans,trans-Farnesyl phosphate + CDP
trans,trans-Farnesyl phosphate + CTP <=> trans,trans-Farnesyl diphosphate + CDP
Proansamitocin <=> 19-Chloroproansamitocin
19-Chloroproansamitocin <=> 20-O-Methyl-19-chloroproansamitocin
20-O-Methyl-19-chloroproansamitocin + Carbamoyl phosphate <=> N-Demethyl-desepoxymaytansinol + Orthophosphate
N-Demethyl-desepoxymaytansinol + 2-Methylpropanoyl-CoA <=> N-Demethyl-desepoxyansamitocin P-3 + CoA
N-Demethyl-desepoxyansamitocin P-3 <=> N-Demethylansamitocin P-3
S-Adenosyl-L-methionine + N-Demethylansamitocin P-3 <=> S-Adenosyl-L-homocysteine + Ansamitocin P-3
UDP-glucose + N-Demethylansamitocin P-3 <=> UDP + Ansamitocinoside P-3
Ansamitocinoside P-3 + Carbamoyl phosphate <=> 4''-O-Carbamoyl ansamitocinoside P-3 + Orthophosphate
Cholest-4-en-3-one + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> (25S)-26-Hydroxycholest-4-en-3-one + 2 Oxidized ferredoxin + H2O
Androsta-1,4-diene-3,17-dione + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 9alpha-Hydroxyandrosta-1,4-diene-3,17-dione + 2 Oxidized ferredoxin + H2O
ent-Isokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha-Hydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase]
9beta-Pimara-7,15-diene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 9beta-Pimara-7,15-dien-19-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
9beta-Pimara-7,15-dien-19-ol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 9beta-Pimara-7,15-dien-19-al + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
9beta-Pimara-7,15-dien-19-al + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 9beta-Pimara-7,15-dien-19-oate + [Oxidized NADPH---hemoprotein reductase] + H2O
9beta-Pimara-7,15-diene + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> 9beta-Pimara-7,15-dien-19-oate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
ent-Cassa-12,15-diene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-11beta-Hydroxycassa-12,15-diene + [Oxidized NADPH---hemoprotein reductase] + H2O
Taxa-4(20),11(12)-dien-5alpha-acetoxy-10beta-ol + Oxygen + NADPH + H+ <=> 10beta,14beta-Dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O
Taxusin + Oxygen + NADPH + H+ <=> 7beta-Hydroxytaxusin + NADP+ + H2O
S-Adenosyl-L-methionine + Resveratrol <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4',5-dihydroxy-trans-stilbene
S-Adenosyl-L-methionine + 3-Methoxy-4',5-dihydroxy-trans-stilbene <=> S-Adenosyl-L-homocysteine + Pterostilbene
2 S-Adenosyl-L-methionine + Resveratrol <=> 2 S-Adenosyl-L-homocysteine + Pterostilbene
Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose
Geranylgeranyl diphosphate + H2O <=> (13E)-Labda-7,13-dien-15-ol + Diphosphate
Leukotriene C4 + H2O <=> Leukotriene D4 + L-Glutamate
8-Oxoguanine + H2O <=> Urate + Ammonia
8-Oxo-dGDP + H2O <=> 8-Oxo-dGMP + Orthophosphate
P1,P6-Bis(5'-adenosyl)hexaphosphate + H2O <=> 2 ATP
Bis(5'-adenosyl) pentaphosphate + H2O <=> ATP + ADP
P1,P6-Bis(5'-adenosyl)hexaphosphate + H2O <=> Adenosine 5'-pentaphosphate + AMP
Bis(5'-adenosyl) pentaphosphate + H2O <=> Adenosine tetraphosphate + AMP
3-Hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + (2Z,4Z)-2-Hydroxyhexa-2,4-dienoate
Androstenedione + Acceptor <=> Androsta-1,4-diene-3,17-dione + Reduced acceptor
9alpha-Hydroxyandrosta-1,4-diene-3,17-dione <=> 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
trans,trans-Farnesyl diphosphate <=> 7-epi-alpha-Selinene + Diphosphate
trans,trans-Farnesyl diphosphate <=> alpha-Guaiene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Viridiflorene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-beta-Caryophyllene + Diphosphate
trans,trans-Farnesyl diphosphate <=> 5-epi-alpha-Selinene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Cubebol + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-gamma-Cadinene + Diphosphate
trans,trans-Farnesyl diphosphate <=> delta-Guaiene + Diphosphate
trans,trans-Farnesyl diphosphate <=> gamma-Curcumene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-alpha-Cuprenene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> Avermitilol + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-delta-Cadinene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-T-Muurolol + Diphosphate
9alpha-Copalyl diphosphate <=> (12E)-9alpha-Labda-8(17),12,14-triene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Bicyclogermacrene + Diphosphate
trans,trans-Farnesyl diphosphate <=> 7-epi-Sesquithujene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Sesquithujene + Diphosphate
ent-Copalyl diphosphate <=> ent-Isokaurene + Diphosphate
dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose
8(R)-HPODE <=> 5S,8R-DiHODE
(S)-2,3-Epoxysqualene <=> Shionone
(S)-2,3-Epoxysqualene <=> Parkeol
(S)-2,3-Epoxysqualene <=> Achilleol B
(S)-2,3-Epoxysqualene <=> Glutinol
(S)-2,3-Epoxysqualene <=> Friedelin
(S)-2,3-Epoxysqualene <=> Baccharis oxide
(S)-2,3-Epoxysqualene <=> alpha-seco-Amyrin
(S)-2,3-Epoxysqualene <=> Marneral
(S)-2,3-Epoxysqualene <=> beta-seco-Amyrin
(S)-2,3-Epoxysqualene <=> delta-Amyrin
(S)-2,3-Epoxysqualene <=> Tirucalla-7,24-dien-3beta-ol
(S)-2,3-Epoxysqualene <=> Baruol
Prosolanapyrone III <=> (-)-Solanapyrone A
Delta4-Dafachronic acid <=> Androstenedione
Cholesterol + NAD+ <=> Cholest-4-en-3-one + NADH + H+
Stemod-13(17)-ene + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> syn-Stemoden-19-oate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
(+)-Linalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (E)-3,7-Dimethylocta-1,6-diene-3,8-diol + [Oxidized NADPH---hemoprotein reductase] + H2O
(-)-Linalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (E)-3,7-Dimethylocta-1,6-diene-3,8-diol + [Oxidized NADPH---hemoprotein reductase] + H2O
(E)-3,7-Dimethylocta-1,6-diene-3,8-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (6E)-8-Oxolinalool + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Linalool + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> (6E)-8-Oxolinalool + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
(6E)-8-Hydroxygeraniol + NADP+ <=> (6E)-8-Hydroxygeranial + NADPH + H+
(6E)-8-Hydroxygeranial + NADP+ <=> (6E)-8-Oxogeranial + NADPH + H+
(6E)-8-Hydroxygeraniol + NADP+ <=> (6E)-8-Oxogeraniol + NADPH + H+
(6E)-8-Oxogeraniol + NADP+ <=> (6E)-8-Oxogeranial + NADPH + H+
Eugenol + Carboxylate + NADP+ <=> Coniferyl ester + NADPH + H+
Isoeugenol + Acetate + NADP+ <=> Coniferyl acetate + NADPH + H+
(S)-Benzoin + NADP+ <=> Benzil + NADPH + H+
(R)-Benzoin + NADP+ <=> Benzil + NADPH + H+
Humulene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 10-Hydroxy-alpha-humulene + [Oxidized NADPH---hemoprotein reductase] + H2O
(+)-Sabinene + NADPH + H+ + Oxygen <=> (+)-cis-Sabinol + NADP+ + H2O
Uracil + Reduced FMN + Oxygen <=> (Z)-3-Ureidoacrylate peracid + FMN
Thymine + Reduced FMN + Oxygen <=> (Z)-2-Methylureidoacrylate peracid + FMN
Lupanine + 2 Ferricytochrome c + H2O <=> 17-Hydroxylupanine + 2 Ferrocytochrome c + 2 H+
S-Adenosyl-L-methionine + 5-Guanidino-2-oxopentanoate <=> S-Adenosyl-L-homocysteine + 5-Guanidino-3-methyl-2-oxopentanoate
S-Adenosyl-L-methionine + Geranyl diphosphate <=> S-Adenosyl-L-homocysteine + (E)-2-Methylgeranyl diphosphate
Nigerose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate
Chitobiose + Orthophosphate <=> N-Acetyl-D-glucosamine + N-Acetyl-alpha-D-glucosamine 1-phosphate
4-O-beta-D-Mannopyranosyl-D-glucopyranose + Orthophosphate <=> D-Glucose + D-Mannose 1-phosphate
CTP + 1,2-Diacyl-sn-glycerol <=> CDP + Phosphatidate
ATP + Maltose <=> ADP + alpha-Maltose 1-phosphate
ATP + UDP-N-acetyl-alpha-D-glucosamine <=> ADP + UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate
(Z)-3-Ureidoacrylate peracid + H2O <=> (Z)-3-Peroxyaminoacrylate + Carbamate
(Z)-3-Ureidoacrylate peracid + H2O <=> (Z)-3-Peroxyaminoacrylate + CO2 + Ammonia
(Z)-2-Methylureidoacrylate peracid + H2O <=> (Z)-2-Methylperoxyaminoacrylate + Carbamate
(Z)-2-Methylureidoacrylate peracid + H2O <=> (Z)-2-Methylperoxyaminoacrylate + CO2 + Ammonia
1D-chiro-Inositol + NAD+ <=> 1-Keto-D-chiro-inositol + NADH + H+
1-Keto-D-chiro-inositol <=> 2,4,6/3,5-Pentahydroxycyclohexanone
scyllo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+
scyllo-Inositol + NADP+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADPH + H+
5-Androstene-3,17-dione <=> Androstenedione
Epiandrosterone + NAD+ <=> 5alpha-Androstane-3,17-dione + NADH + H+
Dehydroepiandrosterone + NAD+ <=> 5-Androstene-3,17-dione + NADH + H+
(2S)-Ethylmalonyl-CoA <=> Butanoyl-CoA + CO2
7,8-Dihydroneopterin 3'-triphosphate + H2O <=> 6-Carboxy-5,6,7,8-tetrahydropterin + Acetaldehyde + Triphosphate
4-Hydroxy-2-oxohexanoic acid <=> (2Z,4Z)-2-Hydroxyhexa-2,4-dienoate + H2O
Geranyl diphosphate <=> Tricyclene + Diphosphate
Geranyl diphosphate <=> (E)-beta-Ocimene + Diphosphate
Geranyl diphosphate <=> (+)-3-Carene + Diphosphate
Geranyl diphosphate + H2O <=> 1,8-Cineole + Diphosphate
Geranyl diphosphate <=> (-)-Sabinene + Diphosphate
Geranyl diphosphate <=> (+)-Sabinene + Diphosphate
Copal-8-ol diphosphate <=> Geranylgeranyl diphosphate + H2O
Geranyl diphosphate + H2O <=> (R)-(+)-alpha-Terpineol + Diphosphate
Geranyl diphosphate <=> gamma-Terpinene + Diphosphate
Geranyl diphosphate <=> alpha-Terpinene + Diphosphate
Geranyl diphosphate <=> (+)-Camphene + Diphosphate
Geranyl diphosphate <=> (-)-Camphene + Diphosphate
(E)-2-Methylgeranyl diphosphate + H2O <=> 2-Methylisoborneol + Diphosphate
Geranyl diphosphate <=> (+)-alpha-Pinene + Diphosphate
Geranyl diphosphate <=> (+)-beta-Pinene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Sesquiphellandrene + Diphosphate
2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate
7-Carboxy-7-carbaguanine + Ammonia + ATP <=> 7-Cyano-7-carbaguanine + ADP + Orthophosphate + H2O
(2S)-Ethylmalonyl-CoA <=> (2R)-Ethylmalonyl-CoA
Ureidoacrylate + H2O <=> Aminoacrylate + Carbamate
(Z)-3-Ureidoacrylate peracid + NADH + H+ <=> Ureidoacrylate + NAD+ + H2O
(Z)-3-Peroxyaminoacrylate <=> Aminoacrylate
Aminoacrylate + H2O <=> 3-Oxopropanoate + Ammonia
(-)-endo-Fenchol + NAD+ <=> (1S,4R)-(+)-Fenchone + NADH + H+
(-)-endo-Fenchol + NADP+ <=> (1S,4R)-(+)-Fenchone + NADPH + H+
(+)-Thujan-3-ol + NAD+ <=> (+)-Thujan-3-one + NADH + H+
(+)-Thujan-3-ol + NADP+ <=> (+)-Thujan-3-one + NADPH + H+
10-Hydroxy-alpha-humulene + NAD+ <=> Zerumbone + NADH + H+
L-threo-7,8-Dihydrobiopterin + NADP+ <=> Sepiapterin + NADPH + H+
L-threo-Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H+
2,3-Epoxymenaquinone + Gla protein + H2O <=> Menaquinol + Gla protein precursor + CO2 + Oxygen
2,3-Epoxymenaquinone + Dithiothreitol <=> Menaquinone + Oxidized dithiothreitol + H2O
4-Amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-Amino-5-hydroxymethyl-2-methylpyrimidine + Ammonia
alpha-Maltose 1-phosphate + Amylose(n) <=> Orthophosphate + Amylose(n+2)
Starch <=> alpha,alpha-Trehalose
2 Nitric oxide <=> Nitrogen + Oxygen
Methanethiol + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Hydrogen sulfide
Methylamine + Coenzyme M <=> Ammonia + 2-(Methylthio)ethanesulfonate
Dimethylamine + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Methylamine
Coenzyme M + Methyl-Co(III) corrinoid protein <=> 2-(Methylthio)ethanesulfonate + Co(I) corrinoid protein
Methanethiol + Co(I) corrinoid protein <=> Hydrogen sulfide + Methyl-Co(III) corrinoid protein
6-Carboxy-5,6,7,8-tetrahydropterin <=> 7-Carboxy-7-carbaguanine + Ammonia
[(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA <=> AMP + Diphosphate + [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA
trans,trans-Farnesyl diphosphate <=> alpha-Muurolene + Diphosphate
trans,trans-Farnesyl diphosphate <=> gamma-Muurolene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Copaene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Cubebene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Sativene + Diphosphate
all-trans-Heptaprenyl diphosphate <=> Tetraprenyl-beta-curcumene + Diphosphate
L-Lysine <=> (2R,3R)-3-Methylornithine
L-Lysine + (2R,3R)-3-Methylornithine + ATP <=> (2R,3R)-3-Methylornithinyl-N6-lysine + Products of ATP breakdown
(2R,3R)-3-Methylornithinyl-N6-lysine + NAD+ + H2O <=> (2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine + Ammonia + NADH + H+
(2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine <=> L-Pyrrolysine + H2O
Methylamine + Co(I) corrinoid protein <=> Ammonia + Methyl-Co(III) corrinoid protein
Dimethylamine + Co(I) corrinoid protein <=> Methylamine + Methyl-Co(III) corrinoid protein
Trimethylamine + Co(I) corrinoid protein <=> Dimethylamine + Methyl-Co(III) corrinoid protein
Tetramethylammonium + Co(I) corrinoid protein <=> Trimethylamine + Methyl-Co(III) corrinoid protein
Papaveroxine <=> Narcotine hemiacetal
Narcotine hemiacetal + NAD+ <=> alpha-Narcotine + NADH + H+
(+)-exo-5-Hydroxycamphor + NAD+ <=> (+)-Bornane-2,5-dione + NADH + H+
5-Oxo-1,2-campholide <=> [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetate
Amorpha-4,11-diene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Artemisinic alcohol + [Oxidized NADPH---hemoprotein reductase] + H2O
Artemisinic alcohol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Artemisinic aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Artemisinic aldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Artemisinate + [Oxidized NADPH---hemoprotein reductase] + H2O
Amorpha-4,11-diene + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Artemisinate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
L-Isoleucine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-isoleucine + [Oxidized NADPH---hemoprotein reductase] + H2O
N-Hydroxy-L-isoleucine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-isoleucine + [Oxidized NADPH---hemoprotein reductase] + H2O
N,N-Dihydroxy-L-isoleucine <=> (E)-2-Methylbutanal oxime + CO2 + H2O
(E)-2-Methylbutanal oxime <=> (Z)-2-Methylbutanal oxime
L-Valine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-valine + [Oxidized NADPH---hemoprotein reductase] + H2O
N-Hydroxy-L-valine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-valine + [Oxidized NADPH---hemoprotein reductase] + H2O
N,N-Dihydroxy-L-valine <=> (E)-2-Methylpropanal oxime + CO2 + H2O
(E)-2-Methylpropanal oxime <=> (Z)-2-Methylpropanal oxime
Dhurrin + H2O <=> (S)-4-Hydroxymandelonitrile + beta-D-Glucose
(Z)-2-Methylbutanal oxime + NADPH + H+ + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + NADP+ + 2 H2O
(2R)-2-Hydroxy-2-methylbutanenitrile + UDP-glucose <=> UDP + Lotaustralin
(Z)-2-Methylpropanal oxime + NADPH + H+ + Oxygen <=> Acetone cyanohydrin + NADP+ + 2 H2O
Lotaustralin + H2O <=> (2R)-2-Hydroxy-2-methylbutanenitrile + beta-D-Glucose
Linamarin + H2O <=> Acetone cyanohydrin + beta-D-Glucose
(E)-Phenylacetaldoxime <=> (Z)-Phenylacetaldehyde oxime
Benzene + Oxygen + NADH + H+ <=> Phenol + NAD+ + H2O
Phenol + Oxygen + NADH + H+ <=> Catechol + NAD+ + H2O
[(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + Oxygen + NADPH + H+ <=> [(2R)-3,3,4-Trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP+ + H2O
(+)-Camphor + NADPH + H+ + Oxygen <=> (+)-6-exo-Hydroxycamphor + NADP+ + H2O
Nicotinate D-ribonucleoside + H2O <=> Nicotinate + D-Ribose
(+)-Camphor + Reduced putidaredoxin + Oxygen <=> (+)-6-endo-Hydroxycamphor + Oxidized putidaredoxin + H2O
Reduced putidaredoxin + NAD+ <=> Oxidized putidaredoxin + NADH + H+
Methylglyoxal + D-Fructose 1,6-bisphosphate <=> D-Glyceraldehyde 3-phosphate + 6-Deoxy-5-ketofructose 1-phosphate
Methylglyoxal + D-Fructose 1-phosphate <=> D-Glyceraldehyde + 6-Deoxy-5-ketofructose 1-phosphate
Bornane-2,6-dione + H2O <=> [(1S)-4-Hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate
(2R,3S)-3-Isopropylmalate + NAD+ <=> 4-Methyl-2-oxopentanoate + CO2 + NADH + H+
L-Gulono-1,4-lactone + Oxygen <=> Ascorbate + Hydrogen peroxide
L-Lysine + NAD+ <=> (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia
Violaxanthin + 2 Ascorbate <=> Zeaxanthin + 2 Dehydroascorbate + 2 H2O
Protein N6,N6-dimethyl-L-lysine + 2 2-Oxoglutarate + 2 Oxygen <=> Protein lysine + 2 Succinate + 2 Formaldehyde + 2 CO2
4,4-Dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + 6 Ferricytochrome b5 + 4 H2O
L-Tyrosine + 2 NADP+ + 2 Iodide <=> 3,5-Diiodo-L-tyrosine + 2 NADPH
2 S-Adenosyl-L-methionine + Glycine <=> 2 S-Adenosyl-L-homocysteine + N,N-Dimethylglycine
2 S-Adenosyl-L-methionine + Sarcosine <=> 2 S-Adenosyl-L-homocysteine + Betaine
3 S-Adenosyl-L-methionine + Glycine <=> 3 S-Adenosyl-L-homocysteine + Betaine
2 UDP-glucose + Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside <=> 2 UDP + Ternatin C5
2 ATP + D-myo-Inositol 1,4,5-trisphosphate <=> 2 ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
ent-Kaurene + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Kaur-16-en-18-oic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Kaur-16-en-18-oic acid + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Gibberellin A12 + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Magnesium protoporphyrin monomethyl ester + 3 NADPH + 3 H+ + 3 Oxygen <=> Divinylprotochlorophyllide + 3 NADP+ + 5 H2O
Flavanone + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 3',5'-Dihydroxyflavanone + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Zeaxanthin + 4 Reduced ferredoxin + 4 H+ + 2 Oxygen <=> Violaxanthin + 4 Oxidized ferredoxin + 2 H2O
(+)-epi-Isozizaene + 4 Reduced [2Fe-2S] ferredoxin + 4 H+ + 2 Oxygen <=> Albaflavenone + 4 Oxidized [2Fe-2S] ferredoxin + 3 H2O
Vetispiradiene + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Solavetivone + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Glutaryl-CoA + Electron-transferring flavoprotein <=> Glutaconyl-1-CoA + Reduced electron-transferring flavoprotein
(11R)-Dihydroartemisinic aldehyde + NADP+ <=> Artemisinic aldehyde + NADPH + H+
1,8-Cineole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2-exo-Hydroxy-1,8-cineole + [Oxidized NADPH---hemoprotein reductase] + H2O
Abietinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abieta-7,13-dien-18,18-diol + [Oxidized NADPH---hemoprotein reductase] + H2O
Abieta-7,13-dien-18,18-diol <=> Abietal + H2O
Cyanate + HCO3- + H+ <=> Ammonia + 2 CO2
Chlorophyllide + 2 Oxygen + 2 NADPH + 2 H+ <=> Chlorophyllide b + 3 H2O + 2 NADP+
2-Oxoglutarate + L-Arginine + Oxygen <=> Succinate + CO2 + L-Hydroxyarginine
L-Hydroxyarginine <=> Guanidine + (S)-1-Pyrroline-5-carboxylate + H2O
L-Glutamate + 2 Oxidized ferredoxin + H2O <=> Ammonia + 2-Oxoglutarate + 2 Reduced ferredoxin + 2 H+
D-Ribose 5-phosphate + D-Glyceraldehyde 3-phosphate + Ammonia <=> Pyridoxal phosphate + 4 H2O + Orthophosphate
D-Ribose 5-phosphate + D-Glyceraldehyde 3-phosphate + L-Glutamine <=> Pyridoxal phosphate + L-Glutamate + 3 H2O + Orthophosphate
Citrate + N6-Acetyl-N6-hydroxy-L-lysine + ATP <=> N2-Citryl-N6-acetyl-N6-hydroxy-L-lysine + AMP + Diphosphate
N2-Citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-Acetyl-N6-hydroxy-L-lysine + ATP <=> Aerobactin + AMP + Diphosphate
HCO3- + H+ <=> CO2 + H2O
ATP + Isopentenyl phosphate <=> ADP + Isopentenyl diphosphate
2'-Deamino-2'-hydroxyneamine + 2-Oxoglutarate <=> 2'-Deamino-2'-hydroxy-6'-dehydroparomamine + L-Glutamate
Decaprenol phosphate + 5-Phospho-alpha-D-ribose 1-diphosphate <=> trans,octacis-Decaprenylphospho-beta-D-ribofuranose 5-phosphate + Diphosphate
UDP-glucose + 2-Deoxystreptamine <=> UDP + 2'-Deamino-2'-hydroxyparomamine
2,4-Dichloro-2,5-dihydro-5-oxofuran-2-acetate <=> cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid
3-O-alpha-D-Glucopyranosyl-L-rhamnopyranose + Orthophosphate <=> L-Rhamnose + beta-D-Glucose 1-phosphate
UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + Acetyl-CoA <=> UDP-N,N'-diacetylbacillosamine + CoA
Acetyl-CoA + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate <=> CoA + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate
4-Methylaminobutyrate + Oxygen + H2O <=> Succinate semialdehyde + Methylamine + Hydrogen peroxide
4-Methylaminobutyrate + Oxygen + H2O <=> 4-Aminobutanoate + Formaldehyde + Hydrogen peroxide
Pseudooxynicotine + H2O + Oxygen <=> 4-Oxo-1-(3-pyridyl)-1-butanone + Methylamine + Hydrogen peroxide
Long-chain acyl-CoA + 2 NADPH + 2 H+ <=> Long-chain alcohol + 2 NADP+ + CoA
4-Oxo-1-(3-pyridyl)-1-butanone + NADP+ + H2O <=> 3-Succinoylpyridine + NADPH + H+
2 L-Arginine + 3 NADH + 3 H+ + 4 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + 3 NAD+ + 4 H2O
L-Arginine + Oxygen + NADH + H+ <=> N(omega)-Hydroxyarginine + NAD+ + H2O
2 N(omega)-Hydroxyarginine + NADH + H+ + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + NAD+ + 2 H2O
5-Nitrosalicylate + Oxygen <=> 2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + Nitrite
5-Nitrosalicylate + Oxygen <=> 4-Nitro-6-oxohepta-2,4-dienedioate
4-Nitro-6-oxohepta-2,4-dienedioate <=> 2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + Nitrite
trans,octacis-Decaprenylphospho-beta-D-ribofuranose + FAD <=> trans,octacis-Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
trans,octacis-Decaprenylphospho-beta-D-arabinofuranose + NAD+ <=> trans,octacis-Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH + H+
Ecgonine methyl ester + NADP+ <=> Ecgonone methyl ester + NADPH + H+
Malonyl-[acp] methyl ester + Malonyl-[acyl-carrier protein] <=> 3-Ketoglutaryl-[acp] methyl ester + CO2 + Acyl-carrier protein
3-Ketoglutaryl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxyglutaryl-[acp] methyl ester + NADP+
3-Hydroxyglutaryl-[acp] methyl ester <=> Enoylglutaryl-[acp] methyl ester + H2O
Enoylglutaryl-[acp] methyl ester + NADPH + H+ <=> Glutaryl-[acp] methyl ester + NADP+
Glutaryl-[acp] methyl ester + Malonyl-[acyl-carrier protein] <=> 3-Ketopimeloyl-[acp] methyl ester + CO2 + Acyl-carrier protein
3-Ketopimeloyl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxypimeloyl-[acp] methyl ester + NADP+
3-Hydroxypimeloyl-[acp] methyl ester <=> Enoylpimeloyl-[acp] methyl ester + H2O
Enoylpimeloyl-[acp] methyl ester + NADPH + H+ <=> Pimeloyl-[acyl-carrier protein] methyl ester + NADP+
Long-chain acyl-[acyl-carrier protein] + 2 Reduced flavodoxin + 3 Oxygen <=> Pimeloyl-[acyl-carrier protein] + n-Alkanal + 2 Oxidized flavodoxin + 3 H2O
Pimeloyl-[acyl-carrier protein] + L-Alanine <=> 8-Amino-7-oxononanoate + Acyl-carrier protein + CO2
beta-Citronellol + NAD+ <=> (R)-(+)-Citronellal + NADH + H+
(-)-Citronellol + NAD+ <=> (S)-(-)-Citronellal + NADH + H+
Biotin sulfoxide + NADPH + H+ <=> Biotin + NADP+ + H2O
Chanoclavine-I + NAD+ <=> Chanoclavine-I aldehyde + NADH + H+
Secoisolariciresinol + 2 NAD+ <=> Matairesinol + 2 NADH + 2 H+
2-Deoxy-scyllo-inosamine + NADP+ <=> 3-Amino-2,3-dideoxy-scyllo-inosose + NADPH + H+
3,3'-Bipyridine-2,2',5,5',6,6'-hexol + NAD+ <=> Blue pigment + NADH + H+
3,3'-Bipyridine-2,2',5,5',6,6'-hexol + NADP+ <=> Blue pigment + NADPH + H+
Azomycin + H2O <=> Imidazol-2-one + Nitrite
Mycophenolic acid O-acyl-glucuronide + H2O <=> Mycophenolate + D-Glucuronate
2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> Maleylpyruvate
Vanillate + Tetrahydrofolate <=> 3,4-Dihydroxybenzoate + 5-Methyltetrahydrofolate
UDP-N-acetyl-alpha-D-glucosamine + Decaprenol phosphate <=> UMP + N-Acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
G00164 + UDP-D-glucuronate <=> G00165 + UDP
G00165 + UDP-N-acetyl-D-glucosamine <=> G13062 + UDP
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + NAD+ <=> UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H+
UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-Glutamate <=> UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-Oxoglutarate
Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-D-galactose <=> CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose
Pentalenolactone D + 2-Oxoglutarate + Oxygen <=> Pentalenolactone E + Succinate + CO2 + H2O
Pentalenolactone E + 2-Oxoglutarate + Oxygen <=> Pentalenolactone F + Succinate + CO2
Pentalenolactone D + 2 2-Oxoglutarate + 2 Oxygen <=> Pentalenolactone F + 2 Succinate + 2 CO2 + H2O
Sulfite + 3 NADH + 3 H+ <=> Hydrogen sulfide + 3 NAD+ + 3 H2O
L-Aspartate 4-semialdehyde + Pyruvate <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
Thiosulfate + Menaquinol <=> HSO3- + Hydrogen sulfide + Menaquinone
Tetrathionate + 2 e- <=> 2 Thiosulfate
Thiosulfate + 5 H2O + 8 Ferricytochrome c <=> 2 Sulfate + 8 Ferrocytochrome c + 10 H+
n Hydrogen sulfide + n Quinone <=> Polysulfide + n Hydroquinone
L-Glutamate <=> 3-Aminopentanedioate
1-Deoxy-11-oxopentalenate + NADPH + H+ + Oxygen <=> Pentalenolactone D + NADP+ + H2O
1-Deoxy-11-oxopentalenate + NADPH + H+ + Oxygen <=> Neopentalenolactone D + NADP+ + H2O
1-Deoxy-11beta-hydroxypentalenate + NAD+ <=> 1-Deoxy-11-oxopentalenate + NADH + H+
1-Deoxypentalenate + 2-Oxoglutarate + Oxygen <=> 1-Deoxy-11beta-hydroxypentalenate + Succinate + CO2
1-Deoxypentalenate + Reduced ferredoxin + Oxygen <=> Pentalenate + Oxidized ferredoxin + H2O
2 Reduced adrenal ferredoxin + NADP+ + H+ <=> 2 Oxidized adrenal ferredoxin + NADPH
Cannabigerolate + Oxygen <=> Cannabidiolic acid + Hydrogen peroxide
Propanoyl-CoA + NAD+ <=> Propenoyl-CoA + NADH + H+
Pentalenolactone F + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Pentalenolactone + 2 Oxidized ferredoxin + 2 H2O
Festuclavine + NAD+ <=> 6,8-Dimethyl-6,7-didehydroergoline + NADH + H+
Hydroxylamine + H2O + 4 Ferricytochrome c <=> Nitrite + 4 Ferrocytochrome c + 5 H+
Hydroxylamine + 3 Ferricytochrome c <=> Nitric oxide + 3 Ferrocytochrome c + 3 H+
4-(3-Methylbut-2-enyl)-L-tryptophan + S-Adenosyl-L-methionine <=> 4-Dimethylallyl-L-abrine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + Squalene <=> S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene <=> S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
2 S-Adenosyl-L-methionine + Squalene <=> 2 S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
3 Malonyl-CoA + Hexanoyl-CoA <=> 3 CoA + 3,5,7-Trioxododecanoyl-CoA + 3 CO2
Octanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 3-Oxodecanoyl-[acp] + CoA + CO2
Malonyl-CoA + 2-Hydroxybenzoyl-CoA <=> 2 CoA + 4-Hydroxycoumarin + CO2
Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-D-glucose <=> CoA + dTDP-4-acetamido-4,6-dideoxy-D-glucose
dTDP-L-rhamnose + N-Acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP + alpha-L-Rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
Geranyl diphosphate + 2,4-Dihydroxy-6-pentylbenzoate <=> Diphosphate + Cannabigerolate
2 Geranylgeranyl diphosphate <=> 15-cis-Phytoene + 2 Diphosphate
4-Aminobutanoate + Pyruvate <=> Succinate semialdehyde + L-Alanine
4-Aminobutanoate + Glyoxylate <=> Succinate semialdehyde + Glycine
L-Tryptophan + Pyruvate <=> Indolepyruvate + L-Alanine
Indolepyruvate + NADPH + H+ + Oxygen <=> Indole-3-acetate + NADP+ + H2O + CO2
CTP + N,N'-Diacetyllegionaminate <=> CMP-N,N'-diacetyllegionaminate + Diphosphate
UTP + N-Acetyl-alpha-D-galactosamine 1-phosphate <=> Diphosphate + UDP-N-acetyl-D-galactosamine
UDP-N,N'-diacetylbacillosamine + tritrans,heptacis-Undecaprenyl phosphate <=> UMP + N,N'-Diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol
ATP + Methylphosphonate <=> alpha-D-Ribose 1-methylphosphonate 5-triphosphate + Adenine
alpha-D-Ribose 1-methylphosphonate 5-triphosphate + H2O <=> alpha-D-Ribose 1-methylphosphonate 5-phosphate + Diphosphate
UDP-N,N'-diacetylbacillosamine + H2O <=> UDP + 2,4-Diacetamido-2,4,6-trideoxy-D-mannopyranose
UDP-N-acetyl-D-galactosamine + N,N'-Diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol <=> UDP + N-Acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol
(S)-2-Hydroxyacid + NAD+ <=> 2-Oxo acid + NADH + H+
dTDP-6-deoxy-beta-L-talose + NAD+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADH + H+
2-Hydroxyethylphosphonate + Oxygen <=> Methylphosphonate + HCO3-
Zeaxanthin + Oxygen <=> (3R)-11-cis-3-Hydroxyretinal + (3R)-all-trans-3-Hydroxyretinal
(+)-Larreatricin + Oxygen + Reduced acceptor <=> (+)-3'-Hydroxylarreatricin + Acceptor + H2O
C30 Botryococcene + NADP+ + Diphosphate <=> Presqualene diphosphate + NADPH + H+
S-Adenosyl-L-methionine + C30 Botryococcene <=> S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene <=> S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene
S-Adenosyl-L-methionine + C30 Botryococcene <=> S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene
S-Adenosyl-L-methionine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene <=> S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene
2 S-Adenosyl-L-methionine + C30 Botryococcene <=> 2 S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene
Acetyl-CoA + Fumigaclavine B <=> CoA + Fumigaclavine A
Fumigaclavine A + Dimethylallyl diphosphate <=> Fumigaclavine C + Diphosphate
Dimethyl sulfone + 2 Reduced FMN + 2 Oxygen <=> Methanesulfonic acid + Formaldehyde + 2 FMN + 2 H2O
alpha-D-Ribose 1-methylphosphonate 5-phosphate + S-Adenosyl-L-methionine + Reduced acceptor <=> alpha-D-Ribose 1,2-cyclic phosphate 5-phosphate + Methane + L-Methionine + 5'-Deoxyadenosine + Acceptor
alpha-D-Ribose 1,2-cyclic phosphate 5-phosphate + H2O <=> D-Ribose 1,5-bisphosphate
Methanesulfonic acid + Reduced FMN + Oxygen <=> FMN + Sulfite + H2O + Formaldehyde
2'-Deamino-2'-hydroxyparomamine + Oxygen <=> 2'-Deamino-2'-hydroxy-6'-dehydroparomamine + Hydrogen peroxide
(3R)-3-Hydroxyacyl-[acyl-carrier protein] <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O
tRNA guanine + 7-Aminomethyl-7-carbaguanine <=> tRNA 7-aminomethyl-7-carbaguanine + Guanine
2-Oxoglutaryl-CoA + H2O <=> 2-Oxoglutarate + CoA
S-(5-Hydroxy-2-furoyl)-CoA + H2O <=> 2-Oxoglutaryl-CoA
Furfural + H2O + Oxygen <=> 2-Furoate + Hydrogen peroxide
2,5-Furandicarboxylate <=> 2-Furoate + CO2
5-Hydroxymethyl-2-furaldehyde + H2O + Oxygen <=> 5-Hydroxymethyl-2-furoate + Hydrogen peroxide
Furfural + NADH + H+ <=> Furfuryl alcohol + NAD+
5-Hydroxymethyl-2-furaldehyde + NADH + H+ <=> 5-Hydroxymethylfurfuryl alcohol + NAD+
Acetyl-CoA + Tetrahydrosarcinapterin <=> CoA + 5-Methyl-H4SPT + CO
S-Adenosyl-L-methionine + tRNA 7-aminomethyl-7-carbaguanine <=> L-Methionine + Adenine + Epoxyqueuosine in tRNA
6-Phospho-D-gluconate + NAD+ <=> D-Ribulose 5-phosphate + CO2 + NADH + H+
(R)-2-Hydroxyacid + NAD+ <=> 2-Oxo acid + NADH + H+
tRNA adenine + H2O <=> tRNA hypoxanthine + Ammonia
Norsolorinic acid anthrone + Oxygen <=> Norsolorinic acid + H2O
Lariciresinol + NADP+ <=> (+)-Pinoresinol + NADPH + H+
Secoisolariciresinol + NADP+ <=> Lariciresinol + NADPH + H+
(-)-Lariciresinol + NADP+ <=> (-)-Pinoresinol + NADPH + H+
(+)-Secoisolariciresinol + NADP+ <=> (-)-Lariciresinol + NADPH + H+
Agroclavine + NADP+ <=> 6,8-Dimethyl-6,7,8,9-tetradehydroergoline + NADPH + H+
Hydroxylamine + Oxygen <=> Nitrite + H2O + H+
tRNA(Ala) adenine + H2O <=> tRNA(Ala) hypoxanthine + Ammonia
tRNA cytosine + H2O <=> tRNA uridine + Ammonia
2 p-Coumaroyl-CoA + Malonyl-CoA + H2O <=> 3 CoA + Bisdemethoxycurcumin + 2 CO2
p-Coumaroyl-CoA + Malonyl-CoA + H2O <=> 2 CoA + 4-Hydroxycinnamoylmethane + 2 CO2
dIDP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Orthophosphate
p-Coumaroyl-D-glucose + Cyanidin 3-O-(6''-glucosyl-2''-xylosylgalactoside) <=> beta-D-Glucose + Cyanidin 3-O-[6-O-(6-O-4-hydroxycinnamoyl-beta-D-glucosyl)-2-O-beta-D-xylosyl-beta-D-galactoside]
p-Coumaroyl-CoA + Anthocyanidin 3-O-beta-D-glucoside <=> CoA + Anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside]
5 Malonyl-CoA <=> 5 CoA + 5,7-Dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + H2O
7 Malonyl-CoA + Hexanoyl-[acp] <=> 7 CoA + Norsolorinic acid anthrone + Acyl-carrier protein + 7 CO2 + 2 H2O
UDP-alpha-D-galactose + Cyanidin <=> UDP + Cyanidin 3-O-galactoside
Copal-8-ol diphosphate + H2O <=> Sclareol + Diphosphate
5alpha-Androstane-3,17-dione + NADP+ <=> Androstenedione + NADPH + H+
Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
Purine deoxyribonucleoside + Orthophosphate <=> Purine + 2-Deoxy-D-ribose 1-phosphate
Iminoglycine + H2O <=> Glyoxylate + Ammonia
L-Tyrosine + S-Adenosyl-L-methionine + Reduced acceptor <=> Iminoglycine + 4-Cresol + 5'-Deoxyadenosine + L-Methionine + Acceptor
1-Deoxy-D-xylulose 5-phosphate + Iminoglycine + Thiocarboxy-[sulfur-carrier protein] <=> 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + Sulfur-carrier protein + 2 H2O
Coniferyl acetate + NADPH + H+ <=> Eugenol + NADP+ + Acetate
Coumaryl acetate + NADPH + H+ <=> Chavicol + NADP+ + Acetate
Eugenol + S-Adenosyl-L-methionine <=> Methyleugenol + S-Adenosyl-L-homocysteine
Chavicol + S-Adenosyl-L-methionine <=> Estragole + S-Adenosyl-L-homocysteine
Isochavicol + S-Adenosyl-L-methionine <=> Anethole + S-Adenosyl-L-homocysteine
Coniferyl alcohol + Acetyl-CoA <=> Coniferyl acetate + CoA
4-Coumaryl alcohol + Acetyl-CoA <=> Coumaryl acetate + CoA
CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + L-Serine <=> CMP + 2,3-Bis-O-(geranylgeranyl)-sn-glycero-1-phospho-L-serine
UDP-D-xylose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin 3-O-beta-D-sambubioside
UDP-D-xylose + Cyanidin 3-O-galactoside <=> UDP + Cyanidin 3-O-(beta-D-xylosyl-(1->2)-beta-D-galactoside)
Quercetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Myricetin + [Oxidized NADPH---hemoprotein reductase] + H2O
1-O-Vanilloyl-beta-D-glucose + Chrysanthemin <=> Vanillate + Cyanidin 3,7-di-O-beta-D-glucoside
Luteolin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Tricetin + [Oxidized NADPH---hemoprotein reductase] + H2O
1-O-Sinapoyl-beta-D-glucose + Chrysanthemin <=> Sinapate + Cyanin
UDP-glucose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin-3,5-diglucoside
UDP-glucose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin 3-O-sophoroside
UDP-glucose + Anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] <=> UDP + Anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside
UDP-glucose + Anthocyanidin 3-O-beta-D-sambubioside <=> UDP + Anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside
UDP-N-acetyl-alpha-D-glucosamine <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + H2O
ADP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> AMP + Orthophosphate + NADH
ADP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> AMP + Orthophosphate + NADPH
Sporulenol <=> Tetraprenyl-beta-curcumene + H2O
5-Phosphooxy-L-lysine + H2O <=> L-2-Aminoadipate 6-semialdehyde + Ammonia + Orthophosphate
trans,trans-Farnesyl diphosphate <=> Delta6-Protoilludene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-alpha-Isocomene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (E)-2-epi-beta-Caryophyllene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-epi-alpha-Bisabolol + Diphosphate
trans,trans-Farnesyl diphosphate <=> Valerena-4,7(11)-diene + Diphosphate
Copal-8-ol diphosphate <=> cis-Abienol + Diphosphate
L-Lysine <=> L-Pipecolate + Ammonia
3,5,7-Trioxododecanoyl-CoA <=> CoA + 2,4-Dihydroxy-6-pentylbenzoate
dTDP-6-deoxy-beta-L-talose <=> dTDP-L-rhamnose
(6R)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide
(6R)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate
beta-Carotene <=> 9-cis-beta-Carotene
(4S)-4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate
(2Z,6Z)-Farnesyl diphosphate <=> 7-Epizingiberene + Diphosphate
Choline <=> Trimethylamine + Acetaldehyde + H+
L-Phenylalanine <=> L-beta-Phenylalanine
L-Phenylalanine <=> D-beta-Phenylalanine
ATP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> ADP + Orthophosphate + NADPH
Coumaryl acetate + NADPH + H+ <=> Isochavicol + Acetate + NADP+
Pelargonidin 3-O-glucoside + UDP-D-xylose <=> Pelargonidin 3-O-beta-D-sambubioside + UDP
Chrysanthemin + UDP-D-xylose <=> Cyanidin 3-O-beta-D-sambubioside + UDP
Delphinidin 3-O-glucoside + UDP-D-xylose <=> Delphinidin 3-O-beta-D-sambubioside + UDP
Pelargonidin 3-O-beta-D-sambubioside + UDP-glucose <=> Pelargonidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP
Cyanidin 3-O-beta-D-sambubioside + UDP-glucose <=> Cyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP
Delphinidin 3-O-beta-D-sambubioside + UDP-glucose <=> Delphinidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP
1-O-Vanilloyl-beta-D-glucose + Pelargonidin 3-O-glucoside <=> Vanillate + Pelargonidin 3,7-di-O-beta-D-glucoside
1-O-Vanilloyl-beta-D-glucose + Delphinidin 3-O-glucoside <=> Vanillate + Delphinidin 3,7-di-O-beta-D-glucoside
Pelargonidin 3-O-glucoside + 1-O-Sinapoyl-beta-D-glucose <=> Pelargonin + Sinapate
Delphinidin 3-O-glucoside + 1-O-Sinapoyl-beta-D-glucose <=> Delphin + Sinapate
S-(Hydroxymethyl)mycothiol + NAD+ + H2O <=> Formate + Mycothiol + NADH + H+
Formaldehyde + Mycothiol <=> S-(Hydroxymethyl)mycothiol
N-Acetyl-beta-D-mannosaminuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose <=> 4-Acetamido-4,6-dideoxy-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-mannosaminuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + dTDP
2,4-Diacetamido-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> N,N'-Diacetyllegionaminate + Orthophosphate
O-Acetyl-L-serine + L-Homocysteine <=> L-Cystathionine + Acetate
3 S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> 3 S-Adenosyl-L-homocysteine + Peptide diphthine
S-Adenosyl-L-methionine + Dihydrosterigmatocystin <=> S-Adenosyl-L-homocysteine + Dihydro-O-methylsterigmatocystin
Geraniol + NAD+ <=> Geranial + NADH + H+
(1'S)-Averantin + NADP+ <=> Norsolorinic acid + NADPH + H+
(1'S,5'S)-5'-Hydroxyaverantin + NAD+ <=> 5'-Oxoaverantin + NADH + H+
(1'S,5'R)-5'-Hydroxyaverantin + NAD+ <=> 5'-Oxoaverantin + NADH + H+
Kanamycin B + 2-Oxoglutarate + Oxygen <=> 2'-Dehydrokanamycin A + Succinate + Ammonia + CO2
11-Oxo-beta-amyrin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 30-Hydroxy-11-oxo-beta-amyrin + [Oxidized NADPH---hemoprotein reductase] + H2O
30-Hydroxy-11-oxo-beta-amyrin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Glycyrrhetaldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Glycyrrhetaldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Glycyrrhetinate + [Oxidized NADPH---hemoprotein reductase] + H2O
11-Oxo-beta-amyrin + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Glycyrrhetinate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
(1'S)-Averantin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (1'S,5'S)-5'-Hydroxyaverantin + [Oxidized NADPH---hemoprotein reductase] + H2O
(1'S)-Averantin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (1'S,5'R)-5'-Hydroxyaverantin + [Oxidized NADPH---hemoprotein reductase] + H2O
O-Methylsterigmatocystin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Aflatoxin B1 + 2 [Oxidized NADPH---hemoprotein reductase] + H2O + Methanol + CO2
Dihydro-O-methylsterigmatocystin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Aflatoxin B2 + 2 [Oxidized NADPH---hemoprotein reductase] + H2O + Methanol + CO2
Tryprostatin B + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxytryprostatin B + [Oxidized NADPH---hemoprotein reductase] + H2O
Cyclo(L-leucyl-L-leucyl) + 6 Reduced ferredoxin + 3 Oxygen <=> Pulcherriminic acid + 6 Oxidized ferredoxin + 4 H2O
Cyclo(L-tyrosyl-L-tyrosyl) + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Mycocyclosin + 2 Oxidized ferredoxin + 2 H2O
D-Glyceraldehyde + H2O + Acceptor <=> D-Glycerate + Reduced acceptor
2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate + 8 NAD+ <=> 2,3-Bis-O-(geranylgeranyl)glycerol 1-phosphate + 8 NADH + 8 H+
2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate + 8 NADP+ <=> 2,3-Bis-O-(geranylgeranyl)glycerol 1-phosphate + 8 NADPH + 8 H+
Cyclo(L-leucyl-L-phenylalanyl) + Oxygen <=> Cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + Hydrogen peroxide
Cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + Oxygen <=> Albonoursin + Hydrogen peroxide
Cyclo(L-leucyl-L-phenylalanyl) + 2 Oxygen <=> Albonoursin + 2 Hydrogen peroxide
Dihydrourocanate + Acceptor <=> Urocanate + Reduced acceptor
2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate + Acceptor <=> 2,3-Bis-O-(geranylgeranyl)glycerol 1-phosphate + Reduced acceptor
5,6,7,8-Tetrahydromethanopterin + NAD+ <=> 7,8-Dihydromethanopterin + NADH + H+
S,S-Dimethyl-beta-propiothetin + Tetrahydrofolate <=> 3-(Methylthio)propanoate + 5-Methyltetrahydrofolate
L-Leucyl-tRNA + L-Phenylalanyl-tRNA(Phe) <=> tRNA(Leu) + tRNA(Phe) + Cyclo(L-leucyl-L-phenylalanyl)
2 L-Tyrosyl-tRNA(Tyr) <=> 2 tRNA(Tyr) + Cyclo(L-tyrosyl-L-tyrosyl)
2 L-Leucyl-tRNA <=> 2 tRNA(Leu) + Cyclo(L-leucyl-L-leucyl)
5-Phospho-alpha-D-ribose 1-diphosphate + 4-Aminobenzoate <=> 4-(beta-D-Ribofuranosyl)aniline 5'-phosphate + CO2 + Diphosphate
S-Adenosylmethioninamine + Agmatine <=> 5'-Methylthioadenosine + N1-(3-Aminopropyl)agmatine
6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-(beta-D-Ribofuranosyl)aniline 5'-phosphate <=> N-[(7,8-Dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + Diphosphate
Dimethylallyl diphosphate + Brevianamide F <=> Diphosphate + Tryprostatin B
Dimethylallyl diphosphate + Verruculogen <=> Diphosphate + Fumitremorgin A
2 ATP <=> 2 Diphosphate + Cyclic di-3',5'-adenylate
Succinyl-CoA + Acetate <=> Acetyl-CoA + Succinate
7,8-Dihydroneopterin 2',3'-cyclic phosphate + H2O <=> Dihydroneopterin phosphate
7,8-Dihydroneopterin 2',3'-cyclic phosphate + H2O <=> 7,8-Dihydroneopterin 2'-phosphate
beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O <=> 2 beta-L-Arabinofuranose
N1-(3-Aminopropyl)agmatine + H2O <=> Spermidine + Urea
GTP + H2O <=> 7,8-Dihydroneopterin 2',3'-cyclic phosphate + Formate + Diphosphate
Geranylgeranyl diphosphate + Indoleglycerol phosphate <=> 3-Geranylgeranylindole + D-Glyceraldehyde 3-phosphate + Diphosphate
3-Geranylgeranylindole + Oxygen + NADPH + H+ <=> 10,11-Epoxy-3-geranylgeranylindole + NADP+ + H2O
Emindole SB + Oxygen + NADPH + H+ <=> 14,15-Epoxyemindole SB + NADP+ + H2O
10,11-Epoxy-3-geranylgeranylindole <=> Emindole SB
14,15-Epoxyemindole SB <=> Paspaline
Paspaline B + NADPH + H+ + Oxygen <=> 12-Demethyl-11,12-dehydropaspaline + NADP+ + H2O + Formate
12-Demethyl-11,12-dehydropaspaline + Oxygen + NADPH + H+ <=> beta-PC-M6 + NADP+ + H2O
beta-PC-M6 + Oxygen + NADPH + H+ <=> 13-Desoxypaxilline + NADP+ + 2 H2O
13-Desoxypaxilline + NADPH + H+ + Oxygen <=> Paxilline + NADP+ + H2O
Paxilline + 2 Dimethylallyl diphosphate <=> 21,22-Diprenylpaxilline + 2 Diphosphate
13-Desoxypaxilline + NADPH + Oxygen + H+ <=> Paspalicine + NADP+ + 2 H2O
Paspalicine + Oxygen + NADPH + H+ <=> Paspalinine + NADP+ + H2O
Paspalinine + Dimethylallyl diphosphate <=> Aflatrem + Diphosphate
13-Desoxyterpendole I + NADPH + H+ + Oxygen <=> Terpendole I + NADP+ + H2O
20,21-Diprenylterpendole I + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitriol + 3 NADP+ + 4 H2O
Lolitrem E + NADPH + Oxygen + H+ <=> Lolitrem B + NADP+ + 2 H2O
Terpendole I + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole I + 2 Diphosphate
Lolitriol + Dimethylallyl diphosphate <=> Lolitrem E + Diphosphate
Paspaline + 2 NADPH + 2 H+ + 2 Oxygen <=> Paspaline B + 2 NADP+ + 3 H2O
Paspaline B <=> Terpendole G
Paspaline + Oxygen + NADPH + H+ <=> Terpendole E + NADP+ + H2O
Terpendole E + 4 NADPH + 4 Oxygen + 4 H+ <=> 13-Desoxyterpendole I + Formate + 4 NADP+ + 5 H2O
12-Demethyl-11,12-dehydropaspaline + 3 Oxygen + 3 NADPH + 3 H+ <=> Terpendole I + 3 NADP+ + 3 H2O
Terpendole I + Dimethylallyl diphosphate <=> Terpendole J + Diphosphate
Terpendole J + NADPH + Oxygen + H+ <=> Terpendole C + NADP+ + 2 H2O
Terpendole C <=> Terpendole K
Terpendole C + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole C + 2 Diphosphate
Terpendole J + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole J + 2 Diphosphate
Methyl-Co(III) corrinoid protein + Tetrahydrosarcinapterin <=> Co(I) corrinoid protein + 5-Methyl-H4SPT
Nitroalkane + H2O + Oxygen <=> Aldehyde + Nitrite + Hydrogen peroxide
Nitroalkane + H2O + Oxygen <=> Ketone + Nitrite + Hydrogen peroxide
Hydrogen + Polysulfide(n) <=> Hydrogen sulfide + Polysulfide(n-1)
(R)-(Homo)2-citrate <=> (-)-threo-Iso(homo)2-citrate
(R)-(Homo)2-citrate <=> cis-(Homo)2-aconitate + H2O
cis-(Homo)2-aconitate + H2O <=> (-)-threo-Iso(homo)2-citrate
(R)-(Homo)3-citrate <=> (-)-threo-Iso(homo)3-citrate
(R)-(Homo)3-citrate <=> cis-(Homo)3-aconitate + H2O
cis-(Homo)3-aconitate + H2O <=> (-)-threo-Iso(homo)3-citrate
7-Oxoheptanoic acid <=> 7-Mercaptoheptanoic acid
Versiconol acetate + H2O <=> Versiconol + Acetate
Versiconol acetate + NADP+ <=> Versiconal hemiacetal acetate + NADPH + H+
Versiconol + NADP+ <=> Versiconal + NADPH + H+
Versiconal hemiacetal acetate + H2O <=> Versiconal + Acetate
Versiconal <=> Versicolorin B + H2O
S-Adenosyl-L-methionine + Dihydrodemethylsterigmatocystin <=> S-Adenosyl-L-homocysteine + Dihydrosterigmatocystin
S-Adenosyl-L-methionine <=> S-Adenosyl-L-homocysteine
Terpendole E <=> Terpendole G
Terpendole G <=> Terpendole B
2-Amino-2-deoxy-D-gluconate + Protein N(pi)-phospho-L-histidine <=> D-Glucosaminate-6-phosphate + Protein histidine
D-Glucosaminate-6-phosphate <=> 2-Dehydro-3-deoxy-6-phospho-D-gluconate + Ammonia
S-Sulfo-L-cysteine + Glutaredoxin <=> L-Cysteine + Sulfite + Glutaredoxin disulfide
beta-Paxitriol <=> Paxilline
D-Glucose + Acceptor <=> D-Glucono-1,5-lactone + Reduced acceptor
(2E,6E)-Farnesol + NAD+ <=> 2-trans,6-trans-Farnesal + NADH + H+
L-Enduracididine + 2-Oxoglutarate + Oxygen <=> (3S)-3-Hydroxy-L-enduracididine + Succinate + CO2
Fumitremorgin C + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 12alpha,13alpha-Dihydroxyfumitremorgin C + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(3S,5S)-Carbapenam-3-carboxylic acid + 2-Oxoglutarate + Oxygen <=> (5R)-Carbapen-2-em-3-carboxylate + Succinate + CO2 + H2O
Tryprostatin A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Fumitremorgin C + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Kanamycin A + NADP+ <=> 2'-Dehydrokanamycin A + NADPH + H+
(S)-2-Chloropropanoate + NADP+ <=> 2-Chloroacrylate + NADPH + H+
Hydrogen sulfide + NAD+ <=> Sulfur + NADH + H+
GDP-beta-L-colitose + NAD+ <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADH + H+
GDP-beta-L-colitose + NADP+ <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADPH + H+
3alpha-Hydroxysteroid + NAD+ <=> 3-Oxosteroid + NADH + H+
3alpha-Hydroxysteroid + NADP+ <=> 3-Oxosteroid + NADPH + H+
UDP-kanosamine + 2'-Deamino-2'-hydroxyneamine <=> UDP + Kanamycin A
UDP-kanosamine + Neamine <=> UDP + Kanamycin B
UDP-kanosamine + Paromamine <=> UDP + Kanamycin C
UDP-kanosamine + 2'-Deamino-2'-hydroxyparomamine <=> UDP + Kanamycin X
Aldopyranose + NAD+ <=> Aldono-1,5-lactone + NADH + H+
Aldopyranose + NADP+ <=> Aldono-1,5-lactone + NADPH + H+
S-Methyl-L-methionine + L-Selenocysteine <=> L-Methionine + Se-Methyl-L-selenocysteine
S-Adenosyl-L-methionine + Phenylpyruvate <=> S-Adenosyl-L-homocysteine + (3S)-2-Oxo-3-phenylbutanoate
UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
UDP-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glc-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
UDP-N-acetyl-D-galactosamine + N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol <=> UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
UDP-alpha-D-galactose + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol <=> UDP + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
S-Adenosyl-L-methionine + 7-(Hydroxymethyl)bacteriochlorophyllide c + H2O <=> 7-(Dihydroxymethyl)bacteriochlorophyllide c + 5'-Deoxyadenosine + L-Methionine
Hydrogen sulfide + NADP+ <=> Sulfur + NADPH + H+
GDP-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol <=> GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
UDP-alpha-D-galactose + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol <=> UDP + alpha-D-Gal-(1->3)-(alpha-L-Fuc-(1->2))-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + L-Serine <=> CMP + 2,3-Bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine
NDP + H2O <=> Nucleoside 5'-phosphate + Orthophosphate
Nucleoside triphosphate + 2 H2O <=> Nucleoside 5'-phosphate + 2 Orthophosphate
2 Caldariellaquinol + Oxygen + n H+ <=> 2 Caldariellaquinone + 2 H2O + n H+
Fumitremorgin B + 2-Oxoglutarate + 2 Oxygen + Reduced acceptor <=> Verruculogen + Succinate + CO2 + H2O + Acceptor
L-Asparagine + 2-Oxoglutarate + Oxygen <=> (2S,3S)-3-Hydroxyasparagine + Succinate + CO2
S-Adenosyl-L-methionine + Benzoate <=> S-Adenosyl-L-homocysteine + Methyl benzoate
S-Adenosyl-L-methionine + Salicylate <=> S-Adenosyl-L-homocysteine + Methyl salicylate
S-Adenosyl-L-methionine + Gibberellin A9 <=> S-Adenosyl-L-homocysteine + Methyl gibberellin A9
S-Adenosyl-L-methionine + Gibberellin A4 <=> S-Adenosyl-L-homocysteine + Methyl gibberellin A4
S-Adenosyl-L-methionine + Anthranilate <=> S-Adenosyl-L-homocysteine + O-Methyl anthranilate
S-Adenosyl-L-methionine + Indole-3-acetate <=> S-Adenosyl-L-homocysteine + Methyl (indol-3-yl)acetate
ATP + 3-Dimethylallyl-4-hydroxybenzoate + 3-Amino-4,7-dihydroxycoumarin <=> AMP + Diphosphate + 8-Demethylnovobiocic acid
S-Adenosyl-L-methionine + 8-Demethylnovobiocic acid <=> S-Adenosyl-L-homocysteine + Novobiocic acid
S-Adenosyl-L-methionine + L-Histidine-[translation elongation factor 2] <=> 5'-Methylthioadenosine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine
Dimethylallyl diphosphate + Brevianamide F <=> Diphosphate + Deoxybrevianamide E
Dimethylallyl diphosphate + 12alpha,13alpha-Dihydroxyfumitremorgin C <=> Diphosphate + Fumitremorgin B
dTDP-4-oxo-5-C-methyl-L-rhamnose + NADH + H+ <=> dTDP-5-dimethyl-L-lyxose + NAD+
GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate <=> GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate
O-Acetyl-L-serine + Hydroxyurea <=> O-Ureido-L-serine + Acetate
ATP + GTP <=> 2 Diphosphate + Cyclic GMP-AMP
L-Threonine + ATP + HCO3- + H+ <=> L-Threonylcarbamoyladenylate + Diphosphate + H2O
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + 1D-myo-Inositol 3-phosphate <=> CMP + 1-Archaetidyl-1D-myo-inositol 3-phosphate
UDP-N-acetyl-D-galactosamine + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
N(omega)-Hydroxyarginine + H2O <=> L-Ornithine + Hydroxyurea
2-Heptyl-4(1H)-quinolone + NADH + H+ + Oxygen <=> 2-Heptyl-3-hydroxy-quinolone + NAD+ + H2O
Heme + 5 Reduced acceptor + 4 Oxygen <=> 5-Oxo-delta-bilirubin + Fe2+ + Formaldehyde + 5 Acceptor + 4 H2O
2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate <=> 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O
O-Ureido-D-serine + ATP + H2O <=> Cycloserine + CO2 + Ammonia + ADP + Orthophosphate
S-Adenosyl-L-methionine + Emodin <=> S-Adenosyl-L-homocysteine + Questin
Acetyl-CoA + Benzyl alcohol <=> CoA + Benzyl acetate
Acetyl-CoA + Cinnamyl alcohol <=> CoA + Cinnamyl acetate
5'-Oxoaverantin <=> (1'S,5'S)-Averufin + H2O
(1'S,5'S)-Averufin + NADPH + H+ + Oxygen <=> 1'-Hydroxyversicolorone + NADP+ + H2O
1'-Hydroxyversicolorone + NADPH + H+ + Oxygen <=> Versiconal hemiacetal acetate + NADP+ + H2O
Versicolorone + NADPH + H+ + Oxygen <=> Versiconol acetate + NADP+ + H2O
Versicolorin B + Oxygen + NADPH + H+ <=> Versicolorin A + NADP+ + 2 H2O
Versicolorin B <=> Dihydrodemethylsterigmatocystin
Versicolorin A <=> 6-Demethylsterigmatocystin
Dihydro-O-methylsterigmatocystin <=> Aflatoxin G2
O-Methylsterigmatocystin <=> Aflatoxin G1
Palmitoyl-CoA + [Protein]-L-cysteine <=> S-Palmitoylprotein + CoA
Malonyl-CoA + (S)-1-Pyrroline-5-carboxylate + H2O <=> CoA + (2S,5S)-trans-Carboxymethylproline + CO2
Maltose 6'-phosphate + H2O <=> Maltose + Orthophosphate
(S)-(2,4-Dichlorophenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Pyruvate + Succinate + CO2
O-Ureido-L-serine <=> O-Ureido-D-serine
S-Adenosyl-L-methionine + gamma-Tocotrienol <=> S-Adenosyl-L-homocysteine + alpha-Tocotrienol
S-Adenosyl-L-methionine + delta-Tocotrienol <=> S-Adenosyl-L-homocysteine + beta-Tocotrienol
trans,trans-Farnesyl diphosphate + H2O <=> Kunzeaol + Diphosphate
6-Tuliposide A <=> Tulipalin A + D-Glucose
2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine <=> Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine
ATP + Agmatine + [tRNA(Ile2)]-cytidine34 + H2O <=> [tRNA(Ile2)]-2-agmatinylcytidine34 + AMP + 2 Orthophosphate
S-Adenosyl-L-methionine + Adenine in rRNA <=> S-Adenosyl-L-homocysteine + N1-Methyladenine in rRNA
S-Adenosyl-L-methionine + 7-[(3S)-3-Amino-3-carboxypropyl]-4-demethylwyosine in tRNA(Phe) <=> S-Adenosyl-L-homocysteine + 7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe)
L-Phenylalanine + 2-Oxo acid <=> Phenylpyruvate + L-Amino acid
Phenylpyruvate + Acetyl-CoA + H2O <=> 2-Benzylmalic acid + CoA
2-Benzylmalic acid <=> 3-Benzylmalic acid
3-Benzylmalic acid + NAD+ <=> 2-Oxo-4-phenylbutyric acid + CO2 + NADH + H+
2-Oxo-4-phenylbutyric acid + L-Amino acid <=> L-Homophenylalanine + 2-Oxo acid
meso-2,3-Butanediol + NAD+ <=> (S)-Acetoin + NADH + H+
meso-2,3-Butanediol + NAD+ <=> (R)-Acetoin + NADH + H+
(S)-2-Acetolactate + Acceptor <=> Diacetyl + CO2 + Reduced acceptor
L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2
3,4-Dehydrolycopene <=> Torulene
Geranyl diphosphate <=> (-)-Bornyl diphosphate
Heme + 5 Reduced acceptor + 4 Oxygen <=> 15-Oxo-beta-bilirubin + Fe2+ + Formaldehyde + 5 Acceptor + 4 H2O
Testosterone + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Estradiol-17beta + Formate + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase]
Hydrogen sulfide + Polysulfide(n) + NADP+ <=> Polysulfide(n+1) + NADPH + H+
Acetyl-CoA + GDP-4-amino-4,6-dideoxy-alpha-D-mannose <=> CoA + GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose
Androstenedione + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Estrone + Formate + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase]
2-Oxo acid + CoA + 2 Oxidized ferredoxin <=> Acyl-CoA + CO2 + 2 Reduced ferredoxin + 2 H+
2 NADH + 2 H+ + Oxygen <=> 2 NAD+ + 2 H2O
2 NADPH + 2 H+ + Oxygen <=> 2 NADP+ + 2 H2O
D-Glucose 6-phosphate + NAD+ <=> 3-Dehydro-D-glucose 6-phosphate + NADH + H+
D-Glucose 6-phosphate + NAD+ <=> D-Glucono-1,5-lactone 6-phosphate + NADH + H+
2-Amino-5-chlorophenol + Oxygen <=> 2-Amino-5-chloromuconate 6-semialdehyde
7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + 2-Oxoglutarate + Oxygen <=> 7-(2-Hydroxy-3-amino-3-carboxypropyl)wyosine in tRNA(Phe) + Succinate + CO2
S-Adenosyl-L-methionine + L-Histidine <=> S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine
S-Adenosyl-L-methionine + Nalpha-Methylhistidine <=> S-Adenosyl-L-homocysteine + N,N-Dimethylhistidine
NDP-glucose + D-Glucose <=> alpha,alpha-Trehalose + NDP
3-Methylbutanoyl-CoA + S-Adenosyl-L-methionine <=> CoA + 5'-Methylthioadenosine + N-Isovaleryl-L-homoserine lactone
(S)-2-(4-Chloro-2-methylphenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 4-Chloro-2-methylphenol + Pyruvate + Succinate + CO2
(R)-2-Hydroxyacid + NADP+ <=> 2-Oxo acid + NADPH + H+
p-Coumaroyl-CoA + S-Adenosyl-L-methionine <=> CoA + 5'-Methylthioadenosine + N-(4-Coumaroyl)-L-homoserine lactone
Protodioscin + H2O <=> 26-Deglucoprotodioscin + D-Glucose
ATP + H2O + Tungstate <=> ADP + Orthophosphate + Tungstate
L-Galactonate <=> 2-Dehydro-3-deoxy-L-galactonate + H2O
Geranylgeranyl diphosphate + H2O <=> (E,E)-Geranyllinalool + Diphosphate
Carbon disulfide + H2O <=> Carbonyl sulfide + Hydrogen sulfide
Carbonyl sulfide + H2O <=> CO2 + Hydrogen sulfide
dTDP-D-fucose <=> dTDP-alpha-D-fucofuranose
GTP + RNA 3'-terminal-phosphate <=> GMP + Diphosphate + RNA terminal-2',3'-cyclic-phosphate
Carbon disulfide + 2 H2O <=> CO2 + 2 Hydrogen sulfide
Mecoprop-P + 2-Oxoglutarate + Oxygen <=> 4-Chloro-2-methylphenol + Pyruvate + Succinate + CO2
Dammarenediol II + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Protopanaxadiol + [Oxidized NADPH---hemoprotein reductase] + H2O
Carbamoyl phosphate + ATP + H2O <=> Diphosphate + O-Carbamoyladenylate + Orthophosphate
(R)-(2,4-Dichlorophenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Pyruvate + Succinate + CO2
O-Carbamoyladenylate + Tobramycin <=> AMP + Nebramycin 5'
O-Carbamoyladenylate + Kanamycin A <=> AMP + 6''-O-Carbamoylkanamycin A
Aclacinomycin T + H2O <=> 15-Demethylaclacinomycin T + Methanol
7-Methylguanosine 5'-phosphate + H2O <=> N7-Methylguanosine + Orthophosphate
Kanosamine 6-phosphate + H2O <=> Kanosamine + Orthophosphate
ATP + 1-Diphosinositol pentakisphosphate <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Long-chain aldehyde + [Protein]-L-cysteine + NADP+ <=> [Protein]-S-(long-chain-acyl)-L-cysteine + NADPH + H+
2-Dehydro-3-deoxy-L-galactonate <=> Pyruvate + L-Glyceraldehyde
Long-chain aldehyde + Reduced FMN + Oxygen <=> Long-chain fatty acid + hn + FMN + H2O
N1-Methylguanine in tRNA(Phe) + Pyruvate + S-Adenosyl-L-methionine <=> 4-Demethylwyosine in tRNA(Phe) + L-Methionine + 5'-Deoxyadenosine + CO2 + H2O
S-Substituted N-acetyl-L-cysteine + H2O <=> S-Substituted L-cysteine + Acetate
N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
D-Ribose 1,5-bisphosphate <=> D-Ribulose 1,5-bisphosphate
ATP + (2S,5S)-trans-Carboxymethylproline <=> AMP + Diphosphate + (3S,5S)-Carbapenam-3-carboxylic acid
9-cis-beta-Carotene + Oxygen <=> 9-cis-10'-Apo-beta-carotenal + beta-Ionone
9-cis-10'-Apo-beta-carotenal + 2 Oxygen <=> Carlactone + (2E,4E,6E)-7-Hydroxy-4-methylhepta-2,4,6-trienal
beta-Carotene + Oxygen <=> all-trans-10'-Apo-beta-carotenal + beta-Ionone
all-trans-10'-Apo-beta-carotenal + Oxygen <=> 13-Apo-beta-carotenone + (2E,4E,6E)-4-Methylocta-2,4,6-trienedial
(R)-5-Phosphomevalonate + ATP <=> Isopentenyl phosphate + ADP + Orthophosphate + CO2
(E,E)-Geranyllinalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (E,E)-4,8,12-Trimethyltrideca-1,3,7,11-tetraene + But-3-en-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
L-Glyceraldehyde + NADPH + H+ <=> Glycerol + NADP+
(S)-5-Amino-3-oxohexanoic acid + Acetyl-CoA <=> L-3-Aminobutyryl-CoA + Acetoacetate
L-Galactonate + NAD+ <=> D-Galacturonate + NADH + H+
beta-Paxitriol <=> Penitrem D
beta-Paxitriol <=> Janthitrem C
12-Demethyl-11,12-dehydropaspaline <=> Terpendole B
Terpendole B <=> 13-Desoxyterpendole I
Hydroquinone + Coenzyme F420 <=> Quinone + Reduced coenzyme F420
dTDP-6-deoxy-D-allose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-allose + NADPH + H+
Secondary alcohol + Coenzyme F420 <=> Ketone + Reduced coenzyme F420
(R)-2-Hydroxyglutarate + Acceptor <=> 2-Oxoglutarate + Reduced acceptor
(9Z)-Octadecenoic acid + Oxygen <=> (8E,10S)-10-Hydroperoxyoctadeca-8-enoate
Linoleate + Oxygen <=> (8E,10S,12Z)-10-Hydroperoxyoctadeca-8,12-dienoate
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> (8E,10S,12Z,15Z)-10-Hydroperoxyoctadeca-8,12,15-trienoate
4-O-(beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + H2O <=> 4-O-(beta-L-Arabinofuranosyl)-(2S,4S)-4-hydroxyproline + beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranose
Avenacoside B + H2O <=> 26-Desgluco-avenacoside B + D-Glucose
Dioscin + 3 H2O <=> D-Glucose + 2 L-Rhamnose + Diosgenin
Dioscin + 2 H2O <=> 2 L-Rhamnose + Diosgenin 3-O-beta-D-glucopyranoside
Chorismate + H2O <=> (4R,5R)-4,5-Dihydroxycyclohexa-1(6),2-diene-1-carboxylate + Pyruvate
trans,trans-Farnesyl diphosphate <=> alpha-Copaene + Diphosphate
Copalyl diphosphate <=> Miltiradiene + Diphosphate
7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine <=> 7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-homocysteine
7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine + CO2 <=> Wybutosine in tRNA(Phe) + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + 6-Hydroxytryprostatin B <=> S-Adenosyl-L-homocysteine + Tryprostatin A
3-Oxodecanoate + Anthraniloyl-CoA <=> CoA + 2-Heptyl-4(1H)-quinolone + CO2 + H2O
Octanoyl-CoA + L-Cysteinyl-protein <=> S-Octanoyl-L-cysteinyl-protein + CoA
Protopanaxadiol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Protopanaxatriol + [Oxidized NADPH---hemoprotein reductase] + H2O
4-Hydroxy-2,5-dimethylfuran-3(2H)-one + NADP+ <=> 4-Hydroxy-5-methyl-2-methylenefuran-3(2H)-one + NADPH + H+
UDP-glucose + Vancomycin aglycone <=> UDP + Desvancosaminyl-vancomycin
dTDP-L-epivancosamine + Desvancosaminyl-vancomycin <=> dTDP + Chloroorienticin B
UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein] <=> UDP + 3-O-[N-Acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein]
Chorismate <=> 3-Hydroxybenzoate + Pyruvate
trans,trans-Farnesyl diphosphate <=> (+)-beta-Chamigrene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Thujopsene + Diphosphate
Acetyl-CoA + Itaconate <=> Acetate + Itaconyl-CoA
Cyclohexane-1-carboxyl-CoA + Electron-transferring flavoprotein <=> Cyclohex-1-ene-1-carboxyl-CoA + Reduced electron-transferring flavoprotein
2 Reduced coenzyme F420 + Oxygen <=> 2 Coenzyme F420 + 2 H2O
Reduced coenzyme F420 + 2 Oxidized ferredoxin <=> Coenzyme F420 + 2 Reduced ferredoxin + 2 H+
D-Galactono-1,5-lactone + H2O <=> D-Galactonate
(S)-Reticuline + S-Adenosyl-L-methionine <=> (S)-Laudanine + S-Adenosyl-L-homocysteine
(R)-Reticuline + S-Adenosyl-L-methionine <=> (-)-Laudanidine + S-Adenosyl-L-homocysteine
UDP-glucose + Ginsenoside Rd <=> UDP + Ginsenoside Rb1
Nicotinate D-ribonucleotide + Phenol <=> Nicotinate + Phenyl 5-phospho-alpha-D-ribofuranoside + H+
UDP-D-xylose + Kaempferol <=> UDP + Kaempferol 3-O-beta-D-xyloside
O-Phospho-L-serine + Thiocarboxy-[sulfur-carrier protein] <=> [Sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + Orthophosphate
S-Adenosyl-L-methionine + 4-Demethylwyosine in tRNA(Phe) <=> 5'-Methylthioadenosine + 7-[(3S)-3-Amino-3-carboxypropyl]-4-demethylwyosine in tRNA(Phe)
L-Malyl-CoA + H2O <=> (S)-Malate + CoA
FAD + [Protein]-L-threonine <=> [Protein]-FMN-L-Threonine + AMP
Acetyl-CoA + Oxalate <=> Acetate + Oxalyl-CoA
D-Glyceraldehyde + NADP+ + H2O <=> D-Glycerate + NADPH + H+
2-Dehydro-3-deoxy-D-galactonate <=> Pyruvate + D-Glyceraldehyde
Mycothiol S-conjugate + H2O <=> S-Substituted N-acetyl-L-cysteine + 1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol
D-Galactose <=> alpha-D-Galactose
3-O-[N-Acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-D-galactosamine <=> 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP
N-Acyl-aromatic-L-amino acid + H2O <=> Aromatic amino acid + Carboxylate
alpha-D-Galactose 1-phosphate + H2O <=> D-Galactose + Orthophosphate
delta-Tocotrienol <=> 6-Geranylgeranyl-2-methylbenzene-1,4-diol
gamma-Tocotrienol <=> 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol
(R)-2-Hydroxyacid + Quinone <=> 2-Oxo acid + Hydroquinone
Narbomycin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Neopikromycin + 2 Oxidized ferredoxin + H2O
Narbomycin + 4 Reduced ferredoxin + 4 H+ + 2 Oxygen <=> Novapikromycin + 4 Oxidized ferredoxin + 2 H2O
10-Deoxymethymycin + 4 Reduced ferredoxin + 4 H+ + 2 Oxygen <=> Novamethymycin + 4 Oxidized ferredoxin + 2 H2O
NAD+ <=> Cyclic ADP-ribose + Nicotinamide + H+
Cyclic ADP-ribose + H2O <=> ADP-ribose
NADP+ <=> 2'-Phospho-cyclic ADP-ribose + Nicotinamide + H+
2'-Phospho-cyclic ADP-ribose + Nicotinate + H+ <=> Nicotinic acid adenine dinucleotide phosphate
NAD+ + Histone N6-acetyl-L-lysine + H2O <=> Nicotinamide + Histone-L-lysine + O-Acetyl-ADP-ribose + H+
NAD+ + Protein N6-acetyl-L-lysine + H2O <=> Nicotinamide + Protein lysine + O-Acetyl-ADP-ribose + H+
alpha-NADH + H+ + Oxygen <=> NAD+ + Hydrogen peroxide
alpha-NADPH + H+ + Oxygen <=> NADP+ + Hydrogen peroxide
(Z)-Phenylacetaldehyde oxime + NADPH + Oxygen + H+ <=> Mandelonitrile + NADP+ + 2 H2O
Mandelonitrile + UDP-glucose <=> Prunasin + UDP
Prunasin + UDP-glucose <=> Amygdalin + UDP
Succinyl-CoA + (R)-2-Methylmalate <=> Succinate + (3R)-Citramalyl-CoA
Succinyl-CoA + (R)-Malate <=> Succinate + (R)-Malyl-CoA
(E)-4-(Trimethylammonio)but-2-enoyl-CoA + L-Carnitine <=> (E)-4-(Trimethylammonio)but-2-enoate + L-Carnitinyl-CoA
4-Trimethylammoniobutanoyl-CoA + L-Carnitine <=> 4-Trimethylammoniobutanoate + L-Carnitinyl-CoA
tRNA containing 6-isopentenyladenosine + Sulfur donor + 2 S-Adenosyl-L-methionine <=> 2-Methylthio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine
tRNA containing 6-isopentenyladenosine + Sulfur donor + S-Adenosyl-L-methionine <=> 2-Thio-N6-dimethylallyladenine in tRNA + L-Methionine + 5'-Deoxyadenosine
2-Thio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-methionine <=> 2-Methylthio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-homocysteine
L-Threonylcarbamoyladenylate + tRNA adenine <=> AMP + N6-L-Threonylcarbamoyladenine in tRNA
N6-L-Threonylcarbamoyladenine in tRNA + Sulfur donor + 2 S-Adenosyl-L-methionine <=> 2-Methylthio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine
N6-L-Threonylcarbamoyladenine in tRNA + Sulfur donor + S-Adenosyl-L-methionine <=> 2-Thio-N6-L-threonylcarbamoyladenine in tRNA + L-Methionine + 5'-Deoxyadenosine
2-Thio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-methionine <=> 2-Methylthio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-homocysteine
[Ribosomal protein S12]-L-aspartate + Sulfur donor + 2 S-Adenosyl-L-methionine <=> [Ribosomal protein S12]-3-methylthioaspartate + S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine
[Ribosomal protein S12]-L-aspartate + Sulfur donor + S-Adenosyl-L-methionine <=> [Ribosomal protein S12]-3-thioaspartate + L-Methionine + 5'-Deoxyadenosine
[Ribosomal protein S12]-3-thioaspartate + S-Adenosyl-L-methionine <=> [Ribosomal protein S12]-3-methylthioaspartate + S-Adenosyl-L-homocysteine
3'-Phosphoadenylyl sulfate + Desulfo-A47934 <=> Adenosine 3',5'-bisphosphate + A47934
20-Oxo-5-O-beta-mycaminosyltylactone + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 5-O-beta-D-Mycaminosyltylonolide + 2 Oxidized ferredoxin + H2O
ATP + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol <=> ADP + 3-O-Phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
S-Adenosyl-L-methionine + 3-O-Phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol <=> S-Adenosyl-L-homocysteine + 3-O-Methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
CTP + Phytol <=> CDP + Phytyl phosphate
Fumarate + Coenzyme M + Coenzyme B <=> Succinate + Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide
L-Tryptophan + L-Proline + 2 ATP <=> Brevianamide F + 2 AMP + 2 Diphosphate
dTDP-beta-L-evernosamine + NADPH + H+ + Oxygen <=> dTDP-N-hydroxy-beta-L-evernosamine + NADP+ + H2O
dTDP-N-hydroxy-beta-L-evernosamine + NADPH + H+ + Oxygen <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + NADP+ + 2 H2O
dTDP-beta-L-evernosamine + 2 NADPH + 2 H+ + 2 Oxygen <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 NADP+ + 3 H2O
UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + NADPH + H+
Chorismate <=> 3-[(1-Carboxyvinyl)oxy]benzoate + H2O
S-Adenosyl-L-methionine + 3-[(1-Carboxyvinyl)oxy]benzoate + H2O <=> 6-Amino-6-deoxyfutalosine + L-Methionine + HCO3-
6-Amino-6-deoxyfutalosine + H2O <=> Dehypoxanthine futalosine + Adenine
6-Deoxocastasterone + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> Castasterone + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase]
(E)-Phenylacetaldoxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
L-Tyrosine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-4-Hydroxyphenylacetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O + CO2
(E)-4-Hydroxyphenylacetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate <=> Glycerone phosphate + L-Aspartate 4-semialdehyde
(3R)-Citramalyl-CoA <=> Acetyl-CoA + Pyruvate
L-Carnitinyl-CoA <=> (E)-4-(Trimethylammonio)but-2-enoyl-CoA + H2O
UDP-2-acetamido-2,6-dideoxy-beta-L-talose <=> UDP-N-acetyl-beta-L-fucosamine
ATP + Citrate + L-Glutamate <=> ADP + Orthophosphate + beta-Citryl-L-glutamate
ATP + N-Acetyl-L-aspartate + L-Glutamate <=> ADP + Orthophosphate + N-Acetylaspartylglutamate
2 ATP + N-Acetyl-L-aspartate + 2 L-Glutamate <=> 2 ADP + 2 Orthophosphate + N-Acetylaspartylglutamylglutamate
S-Adenosyl-L-methionine + (+/-)-Pavine <=> S-Adenosyl-L-homocysteine + N-Methylpavine
Anthraniloyl-CoA + Methanol <=> CoA + O-Methyl anthranilate
6-Deoxocastasterone + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Brassinolide + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase]
6-Deoxotyphasterol + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> 7-Oxatyphasterol + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase]
6-Deoxoteasterone + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> 7-Oxateasterone + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase]
NAD+ + Glycine + [Protein]-L-cysteine <=> ADP-5-ethyl-4-methylthiazole-2-carboxylate + Nicotinamide + [Protein]-dehydroalanine + 3 H2O
Pyridoxal phosphate + L-Histidine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine
N-Acetylaspartylglutamate + H2O <=> N-Acetyl-L-aspartate + L-Glutamate
N-Acetylaspartylglutamylglutamate + H2O <=> N-Acetylaspartylglutamate + L-Glutamate
L-Fucono-1,5-lactone + H2O <=> L-Fuconate
2-Dehydro-3-deoxy-L-fuconate + NAD+ <=> 2,4-Diketo-3-deoxy-L-fuconate + NADH + H+
2,4-Diketo-3-deoxy-L-fuconate + H2O <=> (S)-Lactate + Pyruvate
20,21-Diprenylterpendole J + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitrem E + 3 NADP+ + 4 H2O
ATP + N-Acetylaspartylglutamate + L-Glutamate <=> ADP + Orthophosphate + N-Acetylaspartylglutamylglutamate
20,21-Diprenylterpendole C + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitrem B + 3 NADP+ + 4 H2O
6-Amino-6-deoxyfutalosine + H2O <=> Futalosine + Ammonia
6-Oxocyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA
(S)-2-Phenyloxirane <=> Phenylacetaldehyde
Kanosamine 6-phosphate + 2-Oxoglutarate <=> 3-Dehydro-D-glucose 6-phosphate + L-Glutamate
L-Lysine + 8-Amino-7-oxononanoate <=> L-2-Aminoadipate 6-semialdehyde + 7,8-Diaminononanoate
Hexadecanoyl-[acp] + CoA <=> Palmitoyl-CoA + Acyl-carrier protein
5-O-Caffeoylshikimic acid + H2O <=> Caffeate + Shikimate
Propane + NADH + H+ + Oxygen <=> Propan-2-ol + NAD+ + H2O
Propan-2-ol + NAD+ <=> Acetone + NADH + H+
Acetone + NADPH + H+ + Oxygen <=> Methyl acetate + NADP+ + H2O
Methyl acetate + H2O <=> Acetate + Methanol
2'-(5-Triphosphoribosyl)-3'-dephospho-CoA + Apo-[acyl-carrier-protein] <=> Acyl-carrier protein + Diphosphate
Acetyl-CoA + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CoA + CO2
Geranylgeranyl diphosphate + Homogentisate <=> Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2
S-Adenosyl-L-methionine + 2-Methyl-6-solanyl-1,4-benzoquinol <=> S-Adenosyl-L-homocysteine + Plastoquinol-9
S-Adenosyl-L-methionine + 6-Geranylgeranyl-2-methylbenzene-1,4-diol <=> S-Adenosyl-L-homocysteine + 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol
ADP-5-ethyl-4-methylthiazole-2-carboxylate + H2O <=> 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate + AMP
4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate <=> Thiamin monophosphate + Diphosphate + CO2
Primary alcohol + 2 Ferricytochrome cL <=> Aldehyde + 2 Ferrocytochrome cL + 2 H+
cis-Dec-3-enoyl-[acp] <=> n-7 Unsaturated acyl-[acyl-carrier protein]
(S)-Lactaldehyde + NAD+ <=> Methylglyoxal + NADH + H+
2 S-Adenosyl-L-methionine + Adenine in rRNA <=> 2 S-Adenosyl-L-homocysteine + N6-Dimethyladenine in rRNA
Propane-1,2-diol + NAD+ <=> Hydroxyacetone + NADH + H+
Methylglyoxal + NADH + H+ <=> Hydroxyacetone + NAD+
2,3-Dihydroxypropane-1-sulfonate + NAD+ <=> 2-Hydroxy-3-oxopropane-1-sulfonate + NADH + H+
2 3-Amino-4-hydroxybenzoate + Acetylcysteine + 2 Oxygen <=> Grixazone B + 4 H2O + CO2
3-Methyl-L-tyrosine + Hydrogen peroxide <=> 3-Hydroxy-5-methyl-L-tyrosine + H2O
(2-Amino-1-hydroxyethyl)phosphonate + Oxygen <=> Glycine + Orthophosphate
L-Isoleucine + 2-Oxoglutarate + Oxygen <=> (4S)-4-Hydroxy-L-isoleucine + Succinate + CO2
2-Aminoethylphosphonate + 2-Oxoglutarate + Oxygen <=> (2-Amino-1-hydroxyethyl)phosphonate + Succinate + CO2
5-Methyl-1-naphthoate + NADPH + H+ + Oxygen <=> 3-Hydroxy-5-methyl-1-naphthoate + NADP+ + H2O
trans,trans-Farnesyl diphosphate <=> alpha-Longipinene + Diphosphate
Miltiradiene <=> Abieta-8,11,13-triene
Phylloquinone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> omega-Hydroxyphylloquinone + [Oxidized NADPH---hemoprotein reductase] + H2O
L-Phenylalanine + Tetrahydrobiopterin + Oxygen <=> 3-Hydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin
(R)-2-Methylpyrrolidine + NADP+ <=> 2-Methyl-1-pyrroline + NADPH + H+
(S)-3-Chloro-beta-tyrosyl-[pcp] + FADH2 + Oxygen <=> (S)-3-Chloro-4,5-dihydroxy-beta-phenylalanyl-[pcp] + FAD + H2O
trans,trans-Farnesyl diphosphate <=> (-)-exo-alpha-Bergamotene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-alpha-Santalene + Diphosphate
trans,trans-Farnesyl diphosphate <=> beta-Santalene + Diphosphate
OA-6129 A + 2-Oxoglutarate + Oxygen <=> OA-6129 B2 + Succinate + CO2
(5R)-Carbapen-2-em-3-carboxylate + L-Cysteine <=> C20817 + CO2
C20817 <=> C20818
C20818 <=> C20819
C20819 <=> 2,3-Dihydrothienamycin
2,3-Dihydrothienamycin + 2-Oxoglutarate + Oxygen <=> Thienamycin + Succinate + CO2 + H2O
Epithienamycin F + 2-Oxoglutarate + Oxygen <=> Epithienamycin E + Succinate + CO2 + H2O
Epithienamycin E + 2-Oxoglutarate + Oxygen <=> MM 4550 + Succinate + CO2
C20819 <=> 8-Dehydroxythienamycin
8-Dehydroxythienamycin <=> Thienamycin
Acetyl-CoA + Thienamycin <=> CoA + N-Acetylthienamycin
Acetyl-CoA + Deacetylepithienamycin F <=> CoA + Epithienamycin F
CoA + H2O <=> Pantetheine 4'-phosphate + Adenosine 3',5'-bisphosphate
Pantetheine 4'-phosphate + H2O <=> Pantetheine + Orthophosphate
C20821 + Pantetheine <=> OA-6129 A
OA-6129 B2 <=> OA-6129 B1
3'-Phosphoadenylyl sulfate + OA-6129 B1 <=> Adenosine 3',5'-bisphosphate + OA-6129 C
OA-6129 C + H2O <=> Deacetylepithienamycin F + Pantothenate
C20818 <=> C20822
C20822 <=> C20823
C20823 <=> C20819
C20822 <=> Northienamycin
all-trans-Polyprenyl diphosphate + 1,4-Dihydroxy-2-naphthoate <=> Demethylmenaquinol + Diphosphate + CO2
4-Hydroxybutanoic acid + ATP + CoA <=> 4-Hydroxybutyryl-CoA + ADP + Orthophosphate
3-Hydroxyisovaleryl-CoA <=> 3-Hydroxyisovalerate
6-Deoxy-6-sulfo-D-fructose 1-phosphate <=> Glycerone phosphate + 2-Hydroxy-3-oxopropane-1-sulfonate
Hydroperoxyicosatetraenoate <=> Oxoicosatetraenoate + H2O
all-trans-Pentaprenyl diphosphate + H2O <=> Ophiobolin F + Diphosphate
Geranylgeranyl diphosphate + H2O <=> Cyclooctat-9-en-7-ol + Diphosphate
alpha-L-Fucopyranose <=> beta-L-Fucopyranose
Sulfoquinovose <=> 6-Deoxy-6-sulfo-D-fructose
Hydroperoxyicosatetraenoate <=> Hydroxyepoxyicosatrienoate
Tobramycin + Carbamoyl phosphate + ATP + H2O <=> Nebramycin 5' + AMP + Diphosphate + Orthophosphate
Kanamycin A + Carbamoyl phosphate + ATP + H2O <=> 6''-O-Carbamoylkanamycin A + AMP + Diphosphate + Orthophosphate
ATP + 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + CoA <=> AMP + Diphosphate + 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA
ATP + Delta4-Dafachronic acid + CoA <=> AMP + Diphosphate + (25S)-3-Oxocholest-4-en-26-oyl-CoA
ATP + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoate + CoA <=> AMP + Diphosphate + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
ATP + L-Glutamate + Aniline <=> ADP + Orthophosphate + N5-Phenyl-L-glutamine
2-Amino-2-deoxy-D-gluconate <=> (2Z,4S,5R)-2-Amino-4,5,6-trihydroxyhex-2-enoate + H2O
(2Z,4S,5R)-2-Amino-4,5,6-trihydroxyhex-2-enoate <=> (4S,5R)-4,5,6-Trihydroxy-2-iminohexanoate
(4S,5R)-4,5,6-Trihydroxy-2-iminohexanoate + H2O <=> 2-Dehydro-3-deoxy-D-gluconate + Ammonia
Deoxynucleoside 5'-phosphate + H2O <=> Deoxynucleoside + Orthophosphate
5-Methylbarbiturate + H2O <=> 3-Oxo-3-ureidoisobutyrate
3-Oxo-3-ureidoisobutyrate + H2O <=> Methylmalonate + Urea
(R)-Mevalonate + ATP <=> (R)-Mevalonate 3-phosphate + ADP
(R)-Mevalonate 3-phosphate + ATP <=> (R)-Mevalonate 3,5-bisphosphate + ADP
(R)-Mevalonate 3,5-bisphosphate <=> Isopentenyl phosphate + CO2 + Orthophosphate
4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O
3-Hexenal + NADH + H+ <=> 3-Hexenol + NAD+
Levan + H2O <=> Levan + Levanbiose
UDP-N-acetyl-alpha-D-glucosamine + NAD+ <=> UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+
(S)-2-Hydroxyacid + NADP+ <=> 2-Oxo acid + NADPH + H+
L-Arabinose + NADP+ <=> L-Arabinono-1,4-lactone + NADPH + H+
L-Rhamnose + NADP+ <=> L-Rhamnono-1,4-lactone + NADPH + H+
L-Ornithine + NADPH + H+ + Oxygen <=> N5-Hydroxy-L-ornithine + NADP+ + H2O
L-Ornithine + NADH + H+ + Oxygen <=> N5-Hydroxy-L-ornithine + NAD+ + H2O
Dihydromonacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 3alpha-Hydroxy-3,5-dihydromonacolin L acid + [Oxidized NADPH---hemoprotein reductase] + H2O
3alpha-Hydroxy-3,5-dihydromonacolin L acid <=> Monacolin L acid + H2O
Dihydromonacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Monacolin L acid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Monacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Monacolin J acid + [Oxidized NADPH---hemoprotein reductase] + H2O
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 22-Hydroxydocosahexaenoate + [Oxidized NADPH---hemoprotein reductase] + H2O
2-Hydroxy-5-methyl-1-naphthoate + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 2,7-Dihydroxy-5-methyl-1-naphthoate + 2 Oxidized ferredoxin + H2O
Formate + Coenzyme F420 <=> CO2 + Reduced coenzyme F420
Dihydrosanguinarine + NAD+ <=> Sanguinarine + NADH + H+
Dihydrosanguinarine + NADP+ <=> Sanguinarine + NADPH + H+
Dihydrochelirubine + NAD+ <=> Chelirubine + NADH + H+
Dihydrochelirubine + NADP+ <=> Chelirubine + NADPH + H+
5,6,7,8-Tetrahydromethanopterin + Acceptor <=> 7,8-Dihydromethanopterin + Reduced acceptor
Hydrogen sulfide + 3 Coenzyme F420 + 3 H2O <=> Sulfite + 3 Reduced coenzyme F420
1-Alkyl-2-acylglycerol + UDP-alpha-D-galactose <=> Galactosyl-1-alkyl-2-acylglycerol + UDP
3'-Phosphoadenylyl sulfate + Galactosyl-1-alkyl-2-acylglycerol <=> Adenosine 3',5'-bisphosphate + Seminolipid
Protein glutamine + S-Adenosyl-L-methionine <=> Protein N5-methyl-L-glutamine + S-Adenosyl-L-homocysteine
Diglucosyldiacylglycerol + UDP-glucose <=> Triglucosyldiacylglycerol + UDP
Mannobiose + H2O <=> 2 D-Mannose
Mannobiose <=> 4-O-beta-D-Mannopyranosyl-D-glucopyranose
1,4-beta-D-Mannooligosaccharide(n) + (n-2) Orthophosphate <=> Mannobiose + (n-2) D-Mannose 1-phosphate
S-Adenosyl-L-methionine + m7G(5')pppRm-mRNA <=> S-Adenosyl-L-homocysteine + 5'-(N7-Methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(2'-O-methyl-ribonucleotide)-[mRNA]
n Nucleoside triphosphate <=> 5'-Triphospho-[mRNA](n) + (n-1) Diphosphate
5'-Triphospho-[mRNA] + H2O <=> (5')ppPur-mRNA + Orthophosphate
m7G(5')pppR-mRNA + H2O <=> N7-Methylguanosine 5'-diphosphate + 5'-Phospho-[mRNA]
5'-Triphospho-[mRNA] + H2O <=> 5'-Phospho-[mRNA] + Diphosphate
D-Psicose <=> D-Fructose
D-Tagatose <=> D-Sorbose
alpha-L-Rhamnose <=> beta-L-Rhamnose
ATP + 3-(Methylthio)propanoate + CoA <=> AMP + Diphosphate + 3-(Methylthio)propanoyl-CoA
ATP + (R)-Pantoate + beta-Alanine <=> ADP + Orthophosphate + Pantothenate
ADP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Orthophosphate + DNA(n+m)
GTP + DNA(n) + 5'-Phospho-DNA(m) <=> GMP + Diphosphate + DNA(n+m)
S-Adenosyl-L-methionine + 3'-Hydroxyflavone <=> S-Adenosyl-L-homocysteine + 3'-Methoxyflavone
Very-long-chain acyl-CoA + Malonyl-CoA <=> Very-long-chain 3-oxoacyl-CoA + CO2 + CoA
Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+
Very-long-chain (3R)-3-hydroxyacyl-CoA <=> Very-long-chain trans-2,3-dehydroacyl-CoA + H2O
Very-long-chain acyl-CoA + NADP+ <=> Very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+
beta-D-Mannosyl-1,4-N-acetyl-D-glucosamine + Orthophosphate <=> N-Acetyl-D-glucosamine + D-Mannose 1-phosphate
G00526 + H2O <=> G00711 + D-Glucuronate
G00711 + H2O <=> G10008 + N-Acetyl-D-glucosamine
Cellobionate + Orthophosphate <=> D-Glucose 1-phosphate + D-Gluconic acid
dTDP-L-vancosamine + Desvancosaminyl-vancomycin <=> dTDP + Vancomycin
UDP-glucose + 7-Deoxyloganetate <=> UDP + 7-Deoxyloganate
UDP-glucose + 7-Deoxyloganetin <=> UDP + Deoxyloganin
AMP + Orthophosphate <=> Adenine + D-Ribose 1,5-bisphosphate
CMP + Orthophosphate <=> Cytosine + D-Ribose 1,5-bisphosphate
UMP + Orthophosphate <=> Uracil + D-Ribose 1,5-bisphosphate
O-Acetyl-L-serine + Isoxazolin-5-one <=> 3-(5-Oxoisoxazolin-2-yl)-L-alanine + Acetate
O-Acetyl-L-serine + Isoxazolin-5-one <=> 3-(5-Oxoisoxazolin-4-yl)-L-alanine + Acetate
D-Galacturonate + NAD+ <=> D-Galactaro-1,5-lactone + NADH + H+
D-Glucuronate + NAD+ <=> D-Glucaro-1,5-lactone + NADH + H+
Zeaxanthin + Oxygen <=> beta-Citraurin + (3S)-3-Hydroxycyclocitral
beta-Citraurin + Oxygen <=> Crocetin dialdehyde + (3S)-3-Hydroxycyclocitral
(2S,3S)-3-Methylphenylalanine + 2-Oxoglutarate <=> (3S)-2-Oxo-3-phenylbutanoate + L-Glutamate
D-Galactaro-1,5-lactone <=> D-Galactaro-1,4-lactone
D-Galactaro-1,4-lactone <=> 5-Dehydro-4-deoxy-D-glucarate
L-Gulonate + NAD+ <=> D-Fructuronate + NADH + H+
Phosphatidylglycerol + alpha-Kojibiosyldiacylglycerol <=> 1,2-Diacyl-sn-glycerol + Glycerophosphoglycoglycerolipid
UDP-glucose + 1,2-Diacyl-sn-glycerol <=> UDP + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol
L-Allothreonine + NADP+ <=> L-2-Amino-3-oxobutanoic acid + NADPH + H+
L-Allothreonine + NADP+ <=> Aminoacetone + CO2 + NADPH + H+
5-Hydroxymethyl-2-furaldehyde + Oxygen <=> Furan-2,5-dicarbaldehyde + Hydrogen peroxide
Furan-2,5-dicarbaldehyde + H2O <=> 5-(Dihydroxymethyl)furan-2-carbaldehyde
5-(Dihydroxymethyl)furan-2-carbaldehyde + Oxygen <=> 5-Formyl-2-furoate + Hydrogen peroxide
5-Formyl-2-furoate + H2O <=> 5-(Dihydroxymethyl)furan-2-carboxylate
5-(Dihydroxymethyl)furan-2-carboxylate + Oxygen <=> 2,5-Furandicarboxylate + Hydrogen peroxide
5-Hydroxymethyl-2-furaldehyde + 3 Oxygen + 2 H2O <=> 2,5-Furandicarboxylate + 3 Hydrogen peroxide
1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + H2O + Oxidized flavodoxin <=> 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate + Reduced flavodoxin
D-Glyceraldehyde 3-phosphate + NAD+ + H2O <=> 3-Phospho-D-glycerate + NADH + H+
3,6-Anhydro-alpha-L-galactopyranose + NAD+ + H2O <=> 3,6-Anhydro-L-galactonate + NADH + H+
3,6-Anhydro-alpha-L-galactopyranose + NADP+ + H2O <=> 3,6-Anhydro-L-galactonate + NADPH + H+
Glycerophosphoglycoglycerolipid <=> Lipoteichoic acid
Glycerophosphoglycoglycerolipid <=> Lipoteichoic acid
UDP-alpha-D-galactose + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol <=> UDP + Galactosylglucosyldiacylglycerol
Pyruvate + CoA + Oxidized flavodoxin <=> Acetyl-CoA + CO2 + Reduced flavodoxin
4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 5-Dehydro-4-deoxy-D-glucuronate + N-Acetyl-D-galactosamine 6-sulfate
3'-Phosphoadenylyl sulfate + Dermatan 4-sulfate <=> Adenosine 3',5'-bisphosphate + Dermatan 4,6-sulfate
3'-Phosphoadenylyl sulfate + Chondroitin 4-sulfate <=> Adenosine 3',5'-bisphosphate + Chondroitin 4,6-sulfate
Chondroitin 4-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate
Dermatan 4-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate
Chondroitin 6-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate
3'-Phosphoadenylyl sulfate + Dermatan <=> Adenosine 3',5'-bisphosphate + Dermatan 4-sulfate
dTDP-6-deoxy-D-allose + Mycinamicin VII <=> Mycinamicin VI + dTDP
Mycinamicin VIII + NADPH + Oxygen + H+ <=> Mycinamicin VII + NADP+ + H2O
dTDP-D-desosamine + Protomycinolide IV <=> Mycinamicin VIII + dTDP
Mycinamicin IV + NADPH + Oxygen + H+ <=> Mycinamicin V + NADP+ + H2O
Mycinamicin V + NADPH + Oxygen + H+ <=> Mycinamicin II + NADP+ + H2O
Mycinamicin IV + NADPH + Oxygen + H+ <=> Mycinamicin I + NADP+ + H2O
5 ATP + 3 L-4-Hydroxyphenylglycine + L-Arginine + L-Serine + H2O <=> 5 AMP + 5 Diphosphate + Nocardicin G + L-4-Hydroxyphenylglycyl-L-arginine
S-Adenosyl-L-methionine + Nocardicin G <=> 5'-Methylthioadenosine + Isonocardicin C
Nocardicin C + 2 NADPH + 2 H+ + 2 Oxygen <=> Nocardicin A + 2 NADP+ + 3 H2O
Isonocardicin C <=> Nocardicin C
N-Acetyl-L-2-amino-6-oxopimelate <=> C20911
C20911 <=> C20912
C20912 <=> C20913
C20913 <=> C20914 + CO2
C20914 + L-Threonine <=> C20915
C20915 <=> C20916
C20916 <=> Tabtoxin
Tabtoxin + H2O <=> Tabtoxinine-beta-lactam + L-Threonine
ATP + Tabtoxinine-beta-lactam + L-Threonine <=> ADP + Orthophosphate + Tabtoxin
Acetyl-CoA + Tabtoxinine-beta-lactam <=> CoA + N1-Acetyl-tabtoxinine-beta-lactam
Tabtoxinine-beta-lactam <=> Tabtoxinine-delta-lactam
Tabtoxin <=> Isotabtoxin
Geranylgeranyl diphosphate <=> Cembrene C + Diphosphate
Geranylgeranyl diphosphate + H2O <=> (R)-Nephthenol + Diphosphate
Geranylgeranyl diphosphate <=> Neocembrene + Diphosphate
Geranylgeranyl diphosphate + H2O <=> (1S,4E,8E,12E)-2,2,5,9,13-Pentamethylcyclopentadeca-4,8,12-trien-1-ol + Diphosphate
3,6-Anhydro-L-galactonate <=> 2-Dehydro-3-deoxy-L-galactonate
ATP + UDP-N-acetylmuramate + L-Alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate
ATP + Tyramine + L-Glutamate <=> ADP + Orthophosphate + gamma-Glutamyltyramine
Nocardicin G <=> Nocardicin E
Succinyl-CoA + Mesaconate <=> Succinate + 2-Methylfumaryl-CoA
Hyaluronic acid + H2O <=> Hyaluronic acid + G00526
Hexadecenoyl-[acyl-carrier protein] + KDO2-lipid IVA <=> (9Z)-Hexadec-9-enoyl-KDO2-lipid IV(A) + Acyl-carrier protein
beta-D-Glucose 6-phosphate + NAD+ <=> D-Glucono-1,5-lactone 6-phosphate + NADH + H+
(S)-Ureidoglycine + Glyoxylate <=> Glycine + Oxalureate
3 ATP <=> pppA2'p5'A2'p5'A + 2 Diphosphate
n ATP <=> 2-5A + (n-1) Diphosphate
Aldehyde + Quinone + H2O <=> Carboxylate + Hydroquinone
Aldehyde + Quinone + H2O <=> Fatty acid + Hydroquinone
Hydroxylamine + 2 Ferricytochrome c <=> Nitroxyl + 2 Ferrocytochrome c + 2 H+
Nitroxyl + 2 Ferrocytochrome c + Oxygen + H+ <=> Nitrite + 2 Ferricytochrome c + H2O
Reactive Blue 5 + 2 Hydrogen peroxide <=> Phthalate + 2,2'-Disulfonyl azobenzene + 3-[(4-Amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H2O
(R)-2,3-Dihydroxy-3-methylbutanoate + NAD+ <=> (S)-2-Acetolactate + NADH + H+
L-Dihydroanticapsin + NAD+ <=> L-Anticapsin + NADH + H+
(R)-Ipsdienol + NAD+ <=> Ipsdienone + NADH + H+
(R)-Ipsdienol + NADP+ <=> Ipsdienone + NADPH + H+
Xanthine + 2-Oxoglutarate + Oxygen <=> Urate + Succinate + CO2
beta-Amyrin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Erythrodiol + [Oxidized NADPH---hemoprotein reductase] + H2O
Erythrodiol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Oleanolic aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Oleanolic aldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Oleanolic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
beta-Amyrin + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Oleanolic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Farnesoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Juvenile hormone III acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Eicosanoyl-CoA + Ferrocytochrome b5 + Oxygen + 2 H+ <=> (Z)-Icos-5-enoyl-CoA + Ferricytochrome b5 + 2 H2O
Arsenate ion + Thioredoxin <=> Arsenite + Thioredoxin disulfide + H2O
1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 5-phosphate + Orthophosphate
L-Glutamate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-L-glutamate + ADP + Orthophosphate
LysW-L-glutamate + ATP <=> LysW-L-glutamyl 5-phosphate + ADP
LysW-L-glutamyl 5-phosphate + NADPH + H+ <=> LysW-L-glutamate 5-semialdehyde + NADP+ + Orthophosphate
LysW-L-glutamate 5-semialdehyde + L-Glutamate <=> LysW-L-ornithine + 2-Oxoglutarate
LysW-L-ornithine + H2O <=> L-Ornithine + alpha-Aminoadipate carrier protein LysW
Prephenate <=> 3-[(4R)-4-Hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2
(5-Formylfuran-3-yl)methyl phosphate + Orthophosphate + 2 H2O <=> 2 D-Glyceraldehyde 3-phosphate
3-(Methylthio)acryloyl-CoA + 2 H2O <=> Acetaldehyde + Methanethiol + CoA + CO2
alpha-D-Sedoheptulopyranose 7-phosphate <=> 2-epi-5-epi-Valiolone + Orthophosphate
L-Alanyl-D-glutamate <=> L-Alanyl-L-glutamate
(4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione <=> 3-Hydroxy-5-phosphooxypentane-2,4-dione
ATP + Fumarate + L-2,3-Diaminopropanoate <=> AMP + Diphosphate + N3-Fumaroyl-L-2,3-diaminopropanoate
ATP + N(beta)-Epoxysuccinamoyl-DAP + L-Valine <=> ADP + Orthophosphate + N(beta)-Epoxysuccinamoyl-DAP-Val
ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Valine <=> ADP + Orthophosphate + Dapdiamide A
ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Isoleucine <=> ADP + Orthophosphate + Dapdiamide B
ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Leucine <=> ADP + Orthophosphate + Dapdiamide C
3-(Methylthio)acryloyl-CoA + H2O <=> 3-Hydroxy-3-(methylthio)propanoyl-CoA
3-Hydroxy-3-(methylthio)propanoyl-CoA <=> 3-Oxopropionyl-CoA + Methanethiol
3-Oxopropionyl-CoA + H2O <=> 3-Oxopropanoate + CoA
ATP + HCO3- <=> ADP + Carboxyphosphate
Ammonia + Carboxyphosphate <=> Carbamate + Orthophosphate
1D-myo-Inositol 1,3,4-trisphosphate + H2O <=> D-myo-Inositol 1,3-bisphosphate + Orthophosphate
ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate
1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + 1,2-Diacyl-sn-glycerol
ATP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
Tetracenomycin B2 + 2 Oxygen + H2O + 2 NADPH + 2 H+ <=> 8-Demethyltetracenomycin C + 2 NADP+ + 2 H2O
dTDP-L-rhamnose + 8-Demethyltetracenomycin C <=> dTDP + 8-Demethyl-8-alpha-L-rhamnosyltetracenomycin C
S-Adenosyl-L-methionine + 8-Demethyl-8-alpha-L-rhamnosyltetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C
S-Adenosyl-L-methionine + 8-Demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)tetracenomycin C
S-Adenosyl-L-methionine + 8-Demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin C
S-Adenosyl-L-methionine + 8-Demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + Elloramycin A
10 Malonyl-CoA <=> Tetracenomycin F2 + 10 CoA + 10 CO2 + 2 H2O
Benzoyl-CoA + Reduced acceptor <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Acceptor
S-Adenosyl-L-methionine + 3-Hydroxy-5-methyl-1-naphthoate <=> S-Adenosyl-L-homocysteine + 3-Methoxy-5-methyl-1-naphthoate
S-Adenosyl-L-methionine + 2,7-Dihydroxy-5-methyl-1-naphthoate <=> S-Adenosyl-L-homocysteine + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoate
S-Adenosyl-L-methionine + L-Tyrosine <=> S-Adenosyl-L-homocysteine + 3-Methyl-L-tyrosine
5 Malonyl-CoA <=> 1,3,6,8-Naphthalenetetrol + 5 CoA + 5 CO2 + H2O
Dimethylallyl diphosphate + 5,10-Dihydrophenazine-1-carboxylate <=> Diphosphate + 9-(Dimethylallyl)-5,10-dihydrophenazine-1-carboxylate
3 Malonyl-CoA <=> Phloroglucinol + 3 CoA + 3 CO2
Dimethylallyl diphosphate + L-Tyrosine <=> Diphosphate + 4-O-Dimethylallyl-L-tyrosine
Geranyl diphosphate + Flaviolin <=> 3-Linalylflaviolin + Diphosphate
ATP + 6-Deoxy-6-sulfo-D-fructose <=> ADP + 6-Deoxy-6-sulfo-D-fructose 1-phosphate
3'-Phosphoadenylyl sulfate + alpha,alpha-Trehalose <=> Adenosine 3',5'-bisphosphate + 2-Sulfotrehalose
alpha-D-Ribose 1,2-cyclic phosphate 5-phosphate + H2O <=> D-Ribose 2,5-bisphosphate
D-Ribose 2,5-bisphosphate + H2O <=> D-Ribose 5-phosphate + Orthophosphate
3-Sulfinopropanoyl-CoA + H2O <=> Propanoyl-CoA + Sulfite
[N-(6-Aminohexanoyl)]n(n) + H2O <=> [N-(6-Aminohexanoyl)]n(n-1) + 6-Aminohexanoate
[N-(6-Aminohexanoyl)]n(n) + H2O <=> [N-(6-Aminohexanoyl)]n(n-x) + [N-(6-Aminohexanoyl)]n(x)
6-Aminohexanoate cyclic oligomer + H2O <=> [N-(6-Aminohexanoyl)]n
[N-(6-Aminohexanoyl)]n <=> N-(6-Aminohexanoyl)-6-aminohexanoate
5-Valerolactone + H2O <=> 5-Hydroxypentanoate
5-Hydroxypentanoate + NAD+ <=> 5-Oxopentanoate + NADH + H+
5-Oxopentanoate + NADP+ + H2O <=> Glutarate + NADPH + H+
Juvenile hormone I + H2O <=> Juvenile hormone I acid + Methanol
L-Serine + NADP+ <=> Aminoacetaldehyde + CO2 + NADPH + H+
L-Serine + NAD+ <=> 2-Aminomalonate semialdehyde + NADH + H+
L-Serine + NAD+ <=> Aminoacetaldehyde + CO2 + NADH + H+
Sucrose 6'-phosphate + Orthophosphate <=> D-Glucose 1-phosphate + beta-D-Fructose 6-phosphate
UDP-glucose + beta-D-Glucosyl crocetin <=> UDP + beta-D-Gentiobiosyl crocetin
UDP-glucose + Bis(beta-D-glucosyl) crocetin <=> UDP + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester
UDP-glucose + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester <=> UDP + Crocin
(S)-2-Aminobutanoate + 2-Oxoglutarate <=> 2-Oxobutanoate + L-Glutamate
L-Alanine + 2-Oxobutanoate <=> Pyruvate + (S)-2-Aminobutanoate
ATP + L-Glutamate + (S)-2-Aminobutanoate <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-2-aminobutyrate
ATP + gamma-L-Glutamyl-L-2-aminobutyrate + Glycine <=> ADP + Orthophosphate + Ophthalmate
L-Rhamnose + NAD+ <=> L-Rhamnono-1,4-lactone + NADH + H+
2-Oxobutanoate + Thiamin diphosphate <=> 2-(alpha-Hydroxypropyl)thiamine diphosphate + CO2
2-(alpha-Hydroxypropyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> Enzyme N6-(S-propyldihydrolipoyl)lysine + Thiamin diphosphate
Propanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + Enzyme N6-(S-propyldihydrolipoyl)lysine
Oleoyl-CoA + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 18-Hydroxyoleoyl-CoA + [Oxidized NADPH---hemoprotein reductase] + H2O
Linoleoyl-CoA + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 18-Hydroxylinoleoyl-CoA + [Oxidized NADPH---hemoprotein reductase] + H2O
Phytoceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (2'R)-2'-Hydroxyphytoceramide + 2 Ferricytochrome b5 + H2O
1-Acyl-2-oleoyl-sn-glycero-3-phosphocholine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 1-Acyl-2-[(12R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Ferricytochrome b5 + H2O
Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (2'R)-2'-Hydroxydihydroceramide + 2 Ferricytochrome b5 + H2O
(11Z)-Hexadec-11-enoyl-CoA + Reduced acceptor + Oxygen <=> (10E,12Z)-Hexadeca-10,12-dienoyl-CoA + Acceptor + 2 H2O
N-Acylsphingosine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (4E,8E)-Sphinga-4,8-dienine ceramide + 2 Ferricytochrome b5 + 2 H2O
(4E,8E)-Sphinga-4,8-dienine ceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (4E,8E,10E)-Sphinga-4,8,10-trienine ceramide + 2 Ferricytochrome b5 + 2 H2O
Cholesterol + Oxygen + NADH + H+ <=> 7-Dehydrocholesterol + NAD+ + 2 H2O
Cholesterol + Oxygen + NADPH + H+ <=> 7-Dehydrocholesterol + NADP+ + 2 H2O
Phytoceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (4R,8E)-4-Hydroxysphing-8-enine ceramide + 2 Ferricytochrome b5 + 2 H2O
Phytoceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (4R,8Z)-4-Hydroxysphing-8-enine ceramide + 2 Ferricytochrome b5 + 2 H2O
Palmitoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (14E)-Hexadec-14-enoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Palmitoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (14Z)-Hexadec-14-enoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Hercynine + gamma-L-Glutamyl-L-cysteine + Oxygen <=> gamma-L-Glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O
Hercynine + L-Cysteine + Oxygen <=> S-(Hercyn-2-yl)-L-cysteine S-oxide + H2O
L-Histidine + L-Cysteine + Oxygen <=> S-(L-Histidin-5-yl)-L-cysteine S-oxide + H2O
D-Arginine + Acceptor <=> Iminoarginine + Reduced acceptor
Iminoarginine + H2O <=> 5-Guanidino-2-oxopentanoate + Ammonia
D-Arginine + Acceptor + H2O <=> 5-Guanidino-2-oxopentanoate + Ammonia + Reduced acceptor
5,6,7,8-Tetrahydromonapterin + NADP+ <=> 7,8-Dihydromonapterin + NADPH + H+
S-Adenosyl-L-methionine + dTDP-4-oxo-6-deoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-4-oxo-5-C-methyl-L-rhamnose
gamma-L-Glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O <=> S-(Hercyn-2-yl)-L-cysteine S-oxide + L-Glutamate
2-Aminomuconate semialdehyde <=> Picolinic acid + H2O
S-(Hercyn-2-yl)-L-cysteine S-oxide + Reduced acceptor <=> Ergothioneine + Pyruvate + Ammonia + Acceptor
N-Acetylmuramate + ATP <=> N-Acetylmuramic acid alpha-1-phosphate + ADP
N-Acetylmuramic acid alpha-1-phosphate + UTP <=> UDP-N-acetylmuramate + Diphosphate
(R)-5,6-Dihydrothymine + NAD+ <=> Thymine + NADH + H+
(S)-Methylmalonate semialdehyde <=> (R)-Methylmalonate semialdehyde
2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate <=> DNA 5-hydroxymethylcytosine
DNA 5-methylcytosine + 2-Oxoglutarate + Oxygen <=> DNA 5-hydroxymethylcytosine + Succinate + CO2
5-Guanidino-2-oxopentanoate + NADH + H+ + Ammonia <=> L-Arginine + NAD+ + H2O
5-Guanidino-2-oxopentanoate + NADPH + H+ + Ammonia <=> L-Arginine + NADP+ + H2O
L-Arginine <=> N(omega)-Hydroxyarginine
dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose <=> dTDP-3,4-dioxo-2,6-dideoxy-D-glucose
2-Dehydro-3-deoxy-L-galactonate + NAD+ <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate + NADH + H+
Sulfoquinovose + NAD+ <=> 6-Deoxy-6-sulfo-D-glucono-1,5-lactone + NADH + H+
7,8-Dihydroneopterin + Oxygen <=> 7,8-Dihydroxanthopterin + Formate + Glycolaldehyde
(5-Formylfuran-3-yl)methyl phosphate + L-Alanine <=> [5-(Aminomethyl)furan-3-yl]methyl phosphate + Pyruvate
[5-(Aminomethyl)furan-3-yl]methyl phosphate + ATP <=> [5-(Aminomethyl)furan-3-yl]methyl diphosphate + ADP
[5-(Aminomethyl)furan-3-yl]methyl diphosphate + gamma-Glutamyltyramine <=> (4-{4-[2-(gamma-L-Glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + Diphosphate
S-Adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-L-mannose <=> S-Adenosyl-L-homocysteine + dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose
dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose <=> dTDP-L-oleandrose
Oleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Linoleoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Palmitoleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (9Z,12Z)-Hexadeca-9,12-dienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
2 S-Adenosyl-L-methionine + dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose <=> 2 S-Adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose
dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose
dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-megosamine
(S)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide
5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + H2O <=> 6-Hydroxypseudooxynicotine
(R)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide
dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + NADPH + H+ <=> dTDP-4-oxo-2,6-dideoxy-D-allose + NADP+
all-trans-8'-Apo-beta-carotenal + Oxygen <=> 13-Apo-beta-carotenone + 2,6-Dimethyldeca-2,4,6,8-tetraenedial
UMP + 2-Oxoglutarate + Oxygen <=> 5'-Dehydrouridine + Succinate + CO2 + Orthophosphate
Dodecanoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Hydroxydodecanoate + [Oxidized NADPH---hemoprotein reductase] + H2O
Myrcene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (R)-Ipsdienol + [Oxidized NADPH---hemoprotein reductase] + H2O
2-Hydroxybenzoyl-CoA + NADH + H+ + Oxygen <=> Gentisyl-CoA + NAD+ + H2O
(11Z,14Z)-Icosadienoyl-CoA + Reduced acceptor + Oxygen <=> (5Z,11Z,14Z)-Icosa-5,11,14-trienoyl-CoA + Acceptor + 2 H2O
(11Z,14Z,17Z)-Icosatrienoyl-CoA + Reduced acceptor + Oxygen <=> (5Z,11Z,14Z,17Z)-Icosa-5,11,14,17-tetraenoyl-CoA + Acceptor + 2 H2O
8,11,14-Eicosatrienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Arachidonyl-CoA + 2 Ferricytochrome b5 + 2 H2O
(8Z,11Z,14Z,17Z)-Icosatetraenoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
2-Phytyl-1,4-naphthoquinone + NADPH + H+ <=> Demethylphylloquinol + NADP+
Phosphatidylglycerol + Phosphatidylethanolamine <=> Cardiolipin + Ethanolamine
S-Methyl-L-methionine + L-Homocysteine <=> 2 L-Methionine
L-Anticapsin + L-Alanine + ATP <=> Bacilysin + Orthophosphate + ADP
3-[(4R)-4-Hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate <=> 3-[(1E,4R)-4-Hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate
3-[(1E,4R)-4-Hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate <=> (3E)-3-[(1R,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate
(3E)-3-[(1R,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + NADH + H+ <=> 3-[(1R,2S,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + NAD+
3-[(1R,2S,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-Phenylalanine <=> L-Dihydroanticapsin + Phenylpyruvate
Terpentetriene <=> Terpentecin
trans-Cinnamate <=> Styrene + CO2
Ferulate <=> 4-Vinylguaiacol + CO2
2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one <=> Dihydroneopterin phosphate + H2O
7,8-Dihydroneopterin <=> 7,8-Dihydromonapterin
(S)-Malate <=> (S)-Lactate + CO2
L-Altarate <=> 5-Dehydro-4-deoxy-D-glucarate + H2O
(R)-2-Hydroxyisocaproyl-CoA <=> Isocaprenoyl-CoA + H2O
D-Galactarate <=> (2S,3R)-2,3-Dihydroxy-5-oxohexanedioate + H2O
L-Isoleucine <=> D-allo-Isoleucine
2-epi-5-epi-Valiolone <=> 5-epi-Valiolone
3-D-Glucosyl-1,2-diacylglycerol <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol
2-epi-5-epi-Valiolone 7-phosphate <=> 5-epi-Valiolone 7-phosphate
7,8-Dihydroneopterin 3'-triphosphate <=> 7,8-Dihydromonapterin 3'-triphosphate
D-Glucaro-1,4-lactone <=> 5-Dehydro-4-deoxy-D-glucarate
ATP + L-allo-Isoleucine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-allo-Isoleucyl-[peptidyl-carrier protein]
ATP + L-Arginine + L-Amino acid <=> ADP + Orthophosphate + L-Arginyl-L-amino acid
Geranyl diphosphate + 2-O,3-Dimethylflaviolin <=> Diphosphate + 6-Linalyl-2-O,3-dimethylflaviolin
Geranyl diphosphate + 2-O,3-Dimethylflaviolin <=> Diphosphate + 7-O-Geranyl-2-O,3-dimethylflaviolin
S-Adenosylmethioninamine + Norspermidine <=> 5'-Methylthioadenosine + Norspermine + H+
S-Adenosylmethioninamine + Norspermine <=> 5'-Methylthioadenosine + Caldopentamine + H+
ATP + Protein-L-arginine <=> ADP + Protein N(omega)-phospho-L-arginine
2,6-Dichloro-p-benzoquinone + NADH + H+ <=> 2,6-Dichlorohydroquinone + NAD+
2,5-Dichloro-p-benzoquinone + NADH + H+ <=> 2,5-Dichlorohydroquinone + NAD+
5-Chloro-2-hydroxy-p-benzoquinone + NADH + H+ <=> 5-Chloro-1,2,4-trihydroxybenzene + NAD+
5'-Deoxyadenosine + H2O <=> 5'-Deoxyinosine + Ammonia
Protein N(omega)-phospho-L-arginine + H2O <=> Protein-L-arginine + Orthophosphate
24-Methylenecholesterol + NADPH + H+ <=> 24-epi-Campesterol + NADP+
24-epi-Campesterol + NADPH + H+ + Oxygen <=> Brassicasterol + NADP+ + 2 H2O
2-Iminobutanoate + H2O <=> 2-Oxobutanoate + Ammonia
2-Iminopropanoate + H2O <=> Pyruvate + Ammonia
Dehydroalanine <=> 2-Iminopropanoate
2-Aminobut-2-enoate <=> 2-Iminobutanoate
5-Phospho-alpha-D-ribose 1-diphosphate + 4-Hydroxybenzoate <=> 4-(beta-D-Ribofuranosyl)phenol 5'-phosphate + CO2 + Diphosphate
L-allo-Isoleucyl-[peptidyl-carrier protein] + Peptidyl-carrier protein <=> Peptidyl-carrier protein + L-allo-Isoleucyl-[peptidyl-carrier protein]
NADH + H2O <=> AMP + NMNH
7-Chloro-L-tryptophan + Oxygen <=> Monodechloroaminopyrrolnitrin + CO2 + 2 H2O
Monodechloroaminopyrrolnitrin + FADH2 + Cl- + Oxygen + H+ <=> Aminopyrrolnitrin + FAD + 2 H2O
Aminopyrrolnitrin + 2 NADPH + 2 Oxygen + 2 H+ <=> Pyrrolnitrin + 2 NADP+ + 2 H2O
Hexadecanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> (4Z)-Hexadec-4-enoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O
Hexadecanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> (6Z)-Hexadec-6-enoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O
(9Z,12Z,15Z,18Z,21Z)-Tetracosapentaenoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
(9Z,12Z,15Z,18Z)-Tetracosatetraenoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z,12Z,15Z,18Z)-Tetracosapentaenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Diploptene + S-Adenosyl-L-methionine + Reduced acceptor <=> Adenosylhopane + L-Methionine + Acceptor
Adenosylhopane + H2O <=> Ribosylhopane + Adenine
Ribosylhopane <=> Bacteriohopanetetrol
Bacteriohopanetetrol + UDP-N-acetyl-alpha-D-glucosamine <=> Bacteriohopanetetrol-acetylglucosamine + UDP
Bacteriohopanetetrol-acetylglucosamine + H2O <=> Bacteriohopanetetrol-glucosamine + Acetate
Bacteriohopanetetrol-glucosamine <=> Bacteriohopanetetrol cyclitol ether
Ribosylhopane + L-Glutamate <=> Aminobacteriohopanetriol + 2-Oxoglutarate
L-Tryptophan + Oxygen <=> IPA imine + Hydrogen peroxide
2 IPA imine <=> Chromopyrrolate
Chromopyrrolate + 2 Oxygen + 2 NADH + 3 H+ <=> K-252c + 2 CO2 + 3 H2O + 2 NAD+
K-252c + dTDP-L-ristosamine <=> Holyrine A + dTDP
Holyrine A <=> O-Demethyl-N-demethyl-staurosporine
Acetyl-CoA + 5 Malonyl-CoA + 3 NADPH + 3 H+ <=> 5-Methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+
Acetyl-CoA + 5 Malonyl-CoA + 2 NADPH + 2 H+ <=> 2-Hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 3 H2O + 2 NADP+
Monacolin J acid + (S)-2-Methylbutanoyl-[acp] <=> Lovastatin acid + Acyl-carrier protein
2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate <=> beta-D-Glucose 1-phosphate + Glycerol
1,2-beta-D-Glucan(n) + (n-2) Orthophosphate <=> Sophorose + (n-2) D-Glucose 1-phosphate
O-Demethyl-N-demethyl-staurosporine <=> 3'-Demethylstaurosporine
3-(Methylthio)propanoyl-CoA + FAD <=> 3-(Methylthio)acryloyl-CoA + FADH2
2 IPA imine <=> Protodeoxyviolaceinic acid
Protodeoxyviolaceinic acid + Oxygen + NADPH + H+ <=> Deoxyviolaceinic acid + NADP+ + H2O
Deoxyviolaceinic acid + Oxygen <=> Deoxyviolacein + CO2 + H2O
Protodeoxyviolaceinic acid + NADPH + Oxygen + H+ <=> Protoviolaceinic acid + NADP+ + H2O
Protoviolaceinic acid + Oxygen + NADPH + H+ <=> Violaceinic acid + NADP+ + H2O
Violaceinic acid + Oxygen <=> Violacein + CO2 + H2O
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose
dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-ristosamine
1,3-alpha-D-Glucan(n) + (n-2) Orthophosphate <=> Nigerose + (n-2) beta-D-Glucose 1-phosphate
Pyruvate + trans-2-Octenal <=> (S)-3-Acetyloctanal + CO2
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + 6 Reduced adrenal ferredoxin + 6 H+ + 3 Oxygen <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + 6 Oxidized adrenal ferredoxin + 4 H2O
ATP + (R)-Lipoate + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + AMP + Diphosphate
Isolithocholate + NAD+ <=> 3-Oxo-5beta-cholanate + NADH + H+
Lithocholic acid + NADP+ <=> 3-Oxo-5beta-cholanate + NADPH + H+
Isolithocholate + NADP+ <=> 3-Oxo-5beta-cholanate + NADPH + H+
3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
Aurachin B + H2O <=> 3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
Aurachin B + NAD+ + H2O <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
4-Methyl-5-nitrocatechol + NADH + Oxygen + H+ <=> 2-Hydroxy-5-methylquinone + NAD+ + Nitrite + H2O
Rifampicin + NADH + Oxygen + H+ <=> 2'-N-Hydroxyrifampicin + NAD+ + H2O
Rifampicin + NADPH + Oxygen + H+ <=> 2'-N-Hydroxyrifampicin + NADP+ + H2O
1,3,7-Trimethyluric acid + NADH + H+ + Oxygen <=> 1,3,7-Trimethyl-5-hydroxyisourate + NAD+ + H2O
2 S-Adenosylmethioninamine + Spermidine <=> 2 5'-Methylthioadenosine + N4-Bis(aminopropyl)spermidine
Protoasukamycin + NADH + H+ + Oxygen <=> 4-Hydroxyprotoasukamycin + NAD+ + H2O
Asperlicin C + NADH + H+ + Oxygen <=> Asperlicin E + NAD+ + H2O
Asperlicin C + NADPH + H+ + Oxygen <=> Asperlicin E + NADP+ + H2O
Protodeoxyviolaceinic acid + NADH + H+ + Oxygen <=> Protoviolaceinic acid + NAD+ + H2O
S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + N4-Aminopropylspermidine
S-Adenosylmethioninamine + N4-Aminopropylspermidine <=> 5'-Methylthioadenosine + N4-Bis(aminopropyl)spermidine
Dibenzothiophene + Reduced FMN + Oxygen <=> Dibenzothiophene-5-oxide + FMN + H2O
Dibenzothiophene-5-oxide + Reduced FMN + Oxygen <=> Dibenzothiophene-5,5-dioxide + FMN + H2O
Dibenzothiophene + 2 Reduced FMN + 2 Oxygen <=> Dibenzothiophene-5,5-dioxide + 2 FMN + 2 H2O
Dibenzothiophene-5,5-dioxide + Reduced FMN + Oxygen + NADH <=> 2'-Hydroxybiphenyl-2-sulfinate + FMN + H2O + NAD+ + H+
4 S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> 4 S-Adenosyl-L-homocysteine + Peptide diphthine methyl ester
Peptide diphthine methyl ester + H2O <=> Peptide diphthine + Methanol
CO + Quinone + H2O <=> CO2 + Hydroquinone
Protein N(pi)-phospho-L-histidine + 2-O-(alpha-D-Mannosyl)-D-glycerate <=> Protein histidine + 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate
Protein N(pi)-phospho-L-histidine + Chitobiose <=> Protein histidine + N,N'-Diacetylchitobiose 6'-phosphate
Protein N(pi)-phospho-L-histidine + D-Galactose <=> Protein histidine + D-Galactose 6-phosphate
Protein N(pi)-phospho-L-histidine + Cellobiose <=> Protein histidine + 6-Phospho-beta-D-glucosyl-(1,4)-D-glucose
Adenosylcobalamin 5'-phosphate + H2O <=> Cobamide coenzyme + Orthophosphate
Adenosine-GDP-cobinamide + N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole <=> GMP + Adenosylcobalamin 5'-phosphate
(R,S)-Nicotine + Oxygen <=> N-Methylmyosmine + Hydrogen peroxide
N-Methylmyosmine + H2O <=> Pseudooxynicotine
(R,S)-Nicotine + H2O + Oxygen <=> Pseudooxynicotine + Hydrogen peroxide
Pseudooxynicotine + H2O <=> 3-Succinoylpyridine + Methylamine
3-Succinoylpyridine + H2O + Acceptor <=> 6-Hydroxy-3-succinoylpyridine + Reduced acceptor
Pseudouridine 5'-phosphate + H2O <=> Pseudouridine + Orthophosphate
Isatin + H2O <=> Isatinate
Glycerone phosphate + Acetyl-CoA <=> 3-Hydroxy-5-phosphooxypentane-2,4-dione + CoA
ATP + (S)-4,5-Dihydroxypentane-2,3-dione <=> ADP + (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
ATP + Acarbose <=> ADP + Acarbose 7IV-phosphate
ATP + 2-epi-5-epi-Valiolone <=> ADP + 2-epi-5-epi-Valiolone 7-phosphate
di-trans,poly-cis-Undecaprenyl diphosphate + KDO2-lipid A <=> di-trans,poly-cis-Undecaprenyl phosphate + KDO2-lipid A 1-diphosphate
Dihydromonacolin L-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Dihydromonacolin L acid
Nucleoside 3',5'-bisphosphate + H2O <=> Nucleoside 5'-phosphate + Orthophosphate
2,4-Dinitroanisole + H2O <=> Methanol + 2,4-Dinitrophenol
L-Alanyl-gamma-D-glutamyl-L-lysine + H2O <=> L-Alanyl-D-glutamate + L-Lysine
S-Adenosyl-L-methionine + 7-Demethylmitomycin A <=> S-Adenosyl-L-homocysteine + Mitomycin A
S-Adenosyl-L-methionine + 7-Demethylmitomycin B <=> S-Adenosyl-L-homocysteine + Mitomycin B
S-Adenosyl-L-methionine + (4E,8E)-Sphinga-4,8-dienine ceramide <=> S-Adenosyl-L-homocysteine + 9-Methyl-(4E,8E)-sphinga-4,8-dienine ceramide
2,4-Dimethylphenol + 4 Oxidized azurin + H2O <=> 4-Hydroxy-3-methylbenzaldehyde + 4 Reduced azurin + 4 H+
4-Hydroxy-3-methylbenzaldehyde + NADP+ + H2O <=> 4-Hydroxy-3-methylbenzoate + NADPH + H+
4-Hydroxy-3-methylbenzoate <=> 4-Hydroxyisophthalate
4-Hydroxyisophthalate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NAD+ + CO2
4-Hydroxyisophthalate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NADP+ + CO2
2 Sinapoyl-CoA + Spermidine <=> 2 CoA + N1,N8-Bis(sinapoyl)spermidine
2 p-Coumaroyl-CoA + Spermidine <=> 2 CoA + N1,N8-Bis(4-coumaroyl)spermidine
Palmitoleoyl-CoA + [Wnt]-L-serine <=> CoA + [Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine
[Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine + H2O <=> [Wnt]-L-serine + (9Z)-Hexadecenoic acid
5'-Triphospho-[mRNA] + GDP <=> Diphosphate + G(5')pppPur-mRNA
Phosphatidylethanolamine + KDO2-lipid A <=> 1,2-Diacyl-sn-glycerol + PEtN-KDO2-lipid A
Phosphatidylethanolamine + KDO2-lipid IVA <=> 1,2-Diacyl-sn-glycerol + PEtN-KDO2-lipid IV(A)
Dihydrocaffeoyl-CoA + Caffeate <=> 3,4-Dihydroxyphenylpropanoate + Caffeoyl-CoA
ATP + Prokaryotic ubiquitin-like protein + Protein lysine <=> ADP + Orthophosphate + Pupylated protein
Pupylated protein + H2O <=> Prokaryotic ubiquitin-like protein + Protein lysine
[Prokaryotic ubiquitin-like protein]-L-glutamine + H2O <=> Prokaryotic ubiquitin-like protein + Ammonia
Dihydroanhydropodorhizol + 2-Oxoglutarate + Oxygen <=> Deoxypodophyllotoxin + Succinate + CO2 + H2O
Bursehernin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-5'-Demethylyatein + [Oxidized NADPH---hemoprotein reductase] + H2O
4'-Demethyldeoxypodophyllotoxin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4'-Demethylepipodophyllotoxin + [Oxidized NADPH---hemoprotein reductase] + H2O
2-Dehydro-3,6-dideoxy-6-sulfo-D-gluconate <=> (2S)-3-Sulfolactaldehyde + Pyruvate
6-Deoxy-6-sulfo-D-gluconate <=> 2-Dehydro-3,6-dideoxy-6-sulfo-D-gluconate + H2O
6-Tuliposide B <=> Tulipalin B + D-Glucose
S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine
S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine
S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine
2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine
2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine
S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N5-methyl-L-arginine
Matairesinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pluviatolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Palmitoylphosphatidylcholine + Hexa-acyl lipid A in lipopolysaccharide <=> 2-Acyl-sn-glycero-3-phosphocholine + Hepta-acyl lipid A in lipopolysaccharide
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate + Archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate <=> UDP + Archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy-beta-D-glucuronsyl)-N-acetyl-alpha-D-glucosaminyl phosphate
Dimethylallyl phosphate + Reduced FMN <=> Prenylated FMNH2 + Orthophosphate
Bacteriochlorophyll a + 3 NADP+ <=> Geranylgeranyl bacteriochlorophyllide a + 3 NADPH + 3 H+
Pheophorbide a + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Epoxypheophorbide a + 2 Oxidized ferredoxin + H2O
Epoxypheophorbide a + H2O <=> Red chlorophyll catabolite
GTP + Gentamicin C <=> GDP + Gentamicin C 2''-phosphate
S-Adenosyl-L-methionine + Pluviatolide <=> S-Adenosyl-L-homocysteine + Bursehernin
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NAD+ + 2 H2O <=> L-2-Aminoadipate + NADH + H+
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADP+ + 2 H2O <=> L-2-Aminoadipate + NADPH + H+
5-epi-Valiolone <=> Valienone + H2O
Valienone + ATP <=> Valienone 7-phosphate + ADP
Valienone 7-phosphate <=> 1-epi-Valienol 7-phosphate
Valienone 7-phosphate <=> Validone 7-phosphate
1-epi-Valienol 1-phosphate + Nucleoside triphosphate <=> NDP-1-epi-valienol + Diphosphate
Validone 7-phosphate <=> Validamine 7-phosphate
Validamine 7-phosphate + NDP-1-epi-valienol <=> Validoxylamine A 7'-phosphate + NDP
Validoxylamine A 7'-phosphate + H2O <=> Validoxylamine A + Orthophosphate
Validoxylamine A + UDP-glucose <=> Validamycin A + UDP
6-Deoxy-6-sulfo-D-glucono-1,5-lactone + H2O <=> 6-Deoxy-6-sulfo-D-gluconate
5-epi-Valiolone 7-phosphate + NADH + H+ <=> 5-epi-Valiolol 7-phosphate + NAD+
5-epi-Valiolol 7-phosphate <=> 1-epi-Valienol 7-phosphate
1-epi-Valienol 7-phosphate <=> 1,7-Diphospho-1-epi-valienol
1,7-Diphospho-1-epi-valienol + Nucleoside triphosphate <=> NDP-1-epi-valienol 7-phosphate + Diphosphate
NDP-1-epi-valienol 7-phosphate + dTDP-4-amino-4,6-dideoxy-D-glucose <=> dTDP-acarviose-7-phosphate
dTDP-acarviose-7-phosphate <=> Acarbose 7IV-phosphate
1-epi-Valienol 7-phosphate <=> 1-epi-Valienol 1-phosphate
NDP-1-epi-valienol + 2-Amino-1,5-anhydro-2-deoxyglucitol <=> Salbostatin 6'-phosphate + NDP
Salbostatin 6'-phosphate + H2O <=> Salbostatin + Orthophosphate
2-Amino-5-epi-valiolone <=> 2-Aminovalienone
5-epi-Valiolone <=> 2-Keto-5-epi-valiolone
2-Keto-5-epi-valiolone <=> 2-Amino-5-epi-valiolone
Cetoniacytone B <=> Cetoniacytone A
1-alpha-D-[(1->4)-alpha-D-Glucosyl](n-1)-alpha-D-glucopyranoside + H2O <=> alpha,alpha-Trehalose + Maltodextrin
Maleylpyruvate + H2O <=> Maleic acid + Pyruvate
Protein N(pi)-phospho-L-histidine + H2O <=> Protein histidine + Orthophosphate
Protein N(tau)-phospho-L-histidine + H2O <=> Protein histidine + Orthophosphate
Starch <=> Cyclomaltodextrin
Starch + n H2O <=> (n+1) Maltodextrin
Maltodextrin + H2O <=> Maltose
2-Methylcitrate <=> 2-Methyl-trans-aconitate + H2O
2-Methyl-trans-aconitate <=> (Z)-But-2-ene-1,2,3-tricarboxylate
Ribostamycin + NAD+ <=> 3''-Oxoribostamycin + NADH + H+
3''-Oxoribostamycin + NADPH + H+ <=> Xylostasin + NADP+
Kanamycin X + Oxygen <=> 6'-Oxokanamycin X + Hydrogen peroxide
Kanamycin C + Oxygen <=> 6'-Oxokanamycin C + Hydrogen peroxide
Kanamycin A + 2-Oxoglutarate <=> 6'-Oxokanamycin X + L-Glutamate
Kanamycin B + 2-Oxoglutarate <=> 6'-Oxokanamycin C + L-Glutamate
UDP-glucose + 2'-Deamino-2'-hydroxyneamine <=> UDP + Kanamycin D
UDP-glucose + Neamine <=> UDP + 3''-Deamino-3''-hydroxykanamycin B
Lividamine + Oxygen <=> 6'-Oxolividamine + Hydrogen peroxide
Paromamine + S-Adenosyl-L-methionine + Reduced acceptor <=> 4'-Oxolividamine + L-Methionine + 5'-Deoxyadenosine + Acceptor + H2O
Neamine + S-Adenosyl-L-methionine + Reduced acceptor <=> 4'-Oxonebramine + L-Methionine + 5'-Deoxyadenosine + Acceptor + H2O
4'-Oxolividamine + NADPH + H+ <=> Lividamine + NADP+
4'-Oxonebramine + NADPH + H+ <=> Nebramine + NADP+
UDP-kanosamine + Nebramine <=> UDP + Tobramycin
Kanamycin B + Carbamoyl phosphate + ATP + H2O <=> Nebramycin factor 4 + AMP + Diphosphate + Orthophosphate
5-Phospho-alpha-D-ribose 1-diphosphate + Paromamine <=> Diphosphate + 5''-Phosphoribosylparomamine
5''-Phosphoribosylparomamine + H2O <=> 5-Ribosylparomamine + Orthophosphate
UDP-N-acetyl-alpha-D-glucosamine + 5-Ribosylparomamine <=> UDP + 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II
2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II + H2O <=> 6'''-Deamino-6'''-hydroxyparomomycin II + Acetate
6'''-Deamino-6'''-hydroxyparomomycin II + Oxygen <=> 6'''-Deamino-6'''-oxoparomomycin II + Hydrogen peroxide
Paromomycin II + 2-Oxoglutarate <=> 6'''-Deamino-6'''-oxoparomomycin II + L-Glutamate
Paromomycin II <=> Paromomycin
Paromomycin II <=> 5'''-epi-Lividomycin B
5'''-epi-Lividomycin B <=> Lividomycin B
UDP-D-xylose + Paromamine <=> UDP + Gentamicin A2
Gentamicin A2 + NAD+ <=> 3''-Oxogentamicin A2 + NADH + H+
3''-Oxogentamicin A2 + L-Glutamate <=> 3''-Amino-3''-deoxygentamicin A2 + 2-Oxoglutarate
S-Adenosyl-L-methionine + 3''-Amino-3''-deoxygentamicin A2 <=> S-Adenosyl-L-homocysteine + Gentamicin A
Gentamicin A + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> Gentamicin X2 + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine
Gentamicin X2 + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> Antibiotic G-418 + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine
Gentamicin X2 + FAD <=> 6'-Oxogentamicin X2 + FADH2
Antibiotic G-418 + FAD <=> 6'-Oxo-G418 + FADH2
6'-Oxogentamicin X2 + L-Glutamate <=> Antibiotic JI-20A + 2-Oxoglutarate
6'-Oxo-G418 + L-Glutamate <=> Antibiotic JI-20Ba + 2-Oxoglutarate
6'-Oxo-G418 + L-Glutamate <=> Antibiotic JI-20B + 2-Oxoglutarate
Gentamicin C2 <=> Gentamicin C2a
Antibiotic JI-20B <=> Antibiotic JI-20Ba
Antibiotic JI-20A <=> Gentamicin C1a
Antibiotic JI-20Ba <=> Gentamicin C2a
Antibiotic JI-20B <=> Gentamicin C2
Acarbose 7IV-phosphate <=> Acarbose
UDP-glucose + D-Glucose <=> alpha,alpha-Trehalose + UDP
Cellulose + H2O <=> Cellulose + Cellodextrin
Cellodextrin <=> Cellobiose
Dextran <=> Isomaltose
beta-D-Glucose 1-phosphate <=> D-Glucose 6-phosphate
Levan <=> Levanbiose
4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> Diphosphate + Thiamin monophosphate + CO2
N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-Amino-5-aminomethyl-2-methylpyrimidine + Formate
Thiamine <=> N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
Pentalen-13-al <=> 1-Deoxypentalenate
G13056 + H2O <=> N-Acetyl-D-glucosamine + G10665
G05477 + H2O <=> G10920 + N-Acetyl-D-glucosamine
GDP-L-fucose + G10770 <=> GDP + G05477
Thiamin diphosphate + ADP <=> Thiamin triphosphate + AMP
UDP-D-galactose + Lactosylceramide <=> UDP + iGb3-Cer
UDP-N-acetyl-D-galactosamine + iGb3-Cer <=> UDP + iGb4-Cer
UDP-N-acetyl-D-galactosamine + iGb4-Cer <=> UDP + G02977
dTTP + H2O <=> dTMP + Diphosphate
Secalciferol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitetrol + Oxidized adrenal ferredoxin + H2O
2 Ubiquinol + Oxygen + 4 H+ <=> 2 Ubiquinone + 2 H2O + 4 H+
Sedoheptulose 7-phosphate <=> Demethyl-4-deoxygadusol + Orthophosphate + H2O
Sedoheptulose 7-phosphate <=> 2-epi-Valiolone + Orthophosphate
L-Tryptophan <=> 3-Indoleacrylate + Ammonia
Fe-coproporphyrin III + 2 H+ <=> Coproporphyrin III + Fe2+
D-Erythrulose 1-phosphate <=> Erythrulose 1-phosphate
Erythrulose 1-phosphate <=> D-Erythrulose 4-phosphate
D-Erythrulose 4-phosphate <=> D-Erythrose 4-phosphate
2-Hydroxyisobutanoyl-CoA <=> (S)-3-Hydroxybutanoyl-CoA
2 Ubiquinol + Oxygen + n H+ <=> 2 Ubiquinone + 2 H2O + n H+
(2S,3R)-2-Hydroxy-3-(indol-3-yl)butanoate + NAD+ <=> (R)-3-(Indol-3-yl)-2-oxobutyrate + NADH + H+
(R)-2-Hydroxyglutarate + NAD+ <=> 2-Oxoglutarate + NADH + H+
2-Methylpropane-1,2-diol + NAD+ <=> 2-Hydroxy-2-methylpropanal + NADH + H+
2-Dehydro-3-deoxy-L-rhamnonate + NAD+ <=> 2,4-Diketo-3-deoxy-L-fuconate + NADH + H+
Validamycin A + 2-Oxoglutarate + Oxygen <=> Validamycin B + Succinate + CO2
D-Erythritol 1-phosphate + NADP+ <=> D-Erythrulose 1-phosphate + NADPH + H+
D-Threitol + NAD+ <=> D-Erythrulose + NADH + H+
1-Butanol + Ferricytochrome c <=> Butanal + Ferrocytochrome c + H+
1-Butanol + Quinone <=> Butanal + Hydroquinone
DNA 6-methylaminopurine + 2-Oxoglutarate + Oxygen <=> DNA adenine + Formaldehyde + Succinate + CO2
5-Methylphenazine-1-carboxylate + NADH + Oxygen <=> Pyocyanine + NAD+ + CO2 + H2O
Resorcinol + NADH + H+ + Oxygen <=> Benzene-1,2,4-triol + NAD+ + H2O
Resorcinol + FADH2 + Oxygen <=> Benzene-1,2,4-triol + FAD + H2O
Testosterone + Reduced ferredoxin + Oxygen + H+ <=> 1alpha-Hydroxytestosterone + H2O + Oxidized ferredoxin
2-Hydroxy-2-methylpropanal + NAD+ + H2O <=> 2-Hydroxy-2-methylpropanoate + NADH + H+
Glyoxal + H2O + Oxygen <=> Glyoxylate + Hydrogen peroxide
Methylglyoxal + H2O + Oxygen <=> Pyruvate + Hydrogen peroxide
2,6-Dihydroxybenzoate <=> Resorcinol + CO2
RCH2NHR' + H2O + Oxygen <=> Aldehyde + R'NH2 + Hydrogen peroxide
(25S)-26-Hydroxycholest-4-en-3-one + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> (25S)-26-Oxocholest-4-en-3-one + 2 Oxidized ferredoxin + 2 H2O
(25S)-26-Oxocholest-4-en-3-one + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Delta4-Dafachronic acid + 2 Oxidized ferredoxin + H2O
Cholest-4-en-3-one + 6 Reduced ferredoxin + 6 H+ + 3 Oxygen <=> Delta4-Dafachronic acid + 6 Oxidized ferredoxin + 4 H2O
Cholest-4-en-3-one + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> (25R)-26-Hydroxycholest-4-en-3-one + 2 Oxidized [2Fe-2S] ferredoxin + H2O
(25R)-26-Hydroxycholest-4-en-3-one + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> (25R)-26-Oxocholest-4-en-3-one + 2 Oxidized [2Fe-2S] ferredoxin + 2 H2O
(25R)-26-Oxocholest-4-en-3-one + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> (25R)-3-Oxocholest-4-en-26-oate + 2 Oxidized [2Fe-2S] ferredoxin + H2O
Cholest-4-en-3-one + 6 Reduced [2Fe-2S] ferredoxin + 3 Oxygen <=> (25R)-3-Oxocholest-4-en-26-oate + 6 Oxidized [2Fe-2S] ferredoxin + 4 H2O
3-(1-Carboxyvinyloxy)anthranilate <=> 3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate
3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate <=> 3,4-Dihydro-7-hydroxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate
3,4-Dihydro-7-hydroxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate <=> 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid
3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid <=> 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA
L-Tyrosine <=> (S)-beta-Tyrosine
ATP + (S)-beta-Tyrosine + Peptidyl-carrier protein <=> AMP + Diphosphate + (S)-beta-Tyrosyl-[pcp]
(S)-beta-Tyrosyl-[pcp] + FADH2 + Cl- + Oxygen + H+ <=> (S)-3-Chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
(S)-beta-Tyrosyl-[pcp] <=> 3-(4-Hydroxyphenyl)-3-oxopropanoyl-[pcp]
ATP + 6-Methylsalicylate + CoA <=> AMP + Diphosphate + 6-Methylsalicylyl-CoA
S-Adenosyl-L-methionine + 6-Methylsalicylyl-CoA <=> S-Adenosyl-L-homocysteine + 3,6-Dimethylsalicylyl-CoA
(8S)-3',8-Cyclo-7,8-dihydroguanosine 5'-triphosphate + H2O <=> Precursor Z + Diphosphate
Protoviolaceinic acid + Oxygen + NADH + H+ <=> Violaceinic acid + NAD+ + H2O
Protodeoxyviolaceinic acid + Oxygen + NADH + H+ <=> Deoxyviolaceinic acid + NAD+ + H2O
UDP-D-galactose + Paragloboside <=> UDP + IV4Gala-nLc4-Cer
UDP-D-galactose + Globoside <=> UDP + IV4-alpha-Gal-Gb4Cer
UDP-D-galactose + NORint <=> UDP + NOR2 antigen
UDP-N-acetyl-D-galactosamine + Paragloboside <=> UDP + PX2
UDP-N-acetyl-D-galactosamine + IV4-alpha-Gal-Gb4Cer <=> UDP + NORint
Mandelonitrile + Oxygen <=> Benzoyl cyanide + Hydrogen peroxide
(2E,6E)-Farnesol + Oxygen <=> 2-trans,6-trans-Farnesal + Hydrogen peroxide
Aurachin C + NADH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ + H2O
Aurachin C + NADPH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP+ + H2O
Aurachin C + NADH + H+ + Oxygen <=> Aurachin C epoxide + NAD+ + H2O
Aurachin C + NADPH + H+ + Oxygen <=> Aurachin C epoxide + NADP+ + H2O
Aurachin C epoxide <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
3,6,8-Trihydroxy-2-naphthoate + Reduced acceptor + Oxygen <=> 3,6,7,8-Tetrahydroxy-2-naphthoate + Acceptor + H2O
3,6,7,8-Tetrahydroxy-2-naphthoate <=> 3-Hydroxy-6,7,8-trimethoxy-2-naphthoate
3-Hydroxy-6,7,8-trimethoxy-2-naphthoate <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate
3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate + CoA <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
Azatyrosine <=> (R)-2-Aza-beta-tyrosine
ATP + (R)-2-Aza-beta-tyrosine + Peptidyl-carrier protein <=> AMP + Diphosphate + (R)-2-Aza-beta-tyrosyl-[pcp]
(R)-2-Aza-beta-tyrosyl-[pcp] + FADH2 + Cl- + Oxygen + H+ <=> (R)-2-Aza-3-chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
3-Deoxy-D-manno-octulosonate + Oxygen <=> 8-Dehydro-3-deoxy-D-manno-octulosonate + Hydrogen peroxide
8-Amino-3,8-dideoxy-D-manno-octulosonate + 2-Oxoglutarate <=> 8-Dehydro-3-deoxy-D-manno-octulosonate + L-Glutamate
CTP + 8-Amino-3,8-dideoxy-D-manno-octulosonate <=> Diphosphate + CMP-8-amino-3,8-dideoxy-beta-D-manno-octulosonate
1,2-beta-Oligomannan(n) + Orthophosphate <=> 1,2-beta-Oligomannan(n-1) + D-Mannose 1-phosphate
beta-1,2-Mannobiose + Orthophosphate <=> D-Mannose + D-Mannose 1-phosphate
Dolichyl phosphate D-mannose + [Protein]-L-threonine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein]
ATP + 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] <=> ADP + 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-(6-phospho)mannosyl]-L-threonyl-[protein]
Squalene + FAD + H2O <=> Hydroxysqualene + FADH2
GTP + Valienol 1-phosphate <=> Diphosphate + GDP-valienol
2-Methylpropanamine + FADH2 + Oxygen <=> N-(2-Methylpropanyl)hydroxylamine + FAD + H2O
2-Methylpropanamine + Reduced FMN + Oxygen <=> N-(2-Methylpropanyl)hydroxylamine + FMN + H2O
(S)-Scoulerine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-Nandinine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ATP + Validone <=> ADP + Validone 7-phosphate
UDP-N-acetyl-D-glucosamine + G13027 <=> UDP + G13087
2-Phosphinomethylmalate <=> 3-Phosphinomethylmalate
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia
Presqualene diphosphate + H2O <=> Hydroxysqualene + Diphosphate
2-(Glutathion-S-yl)-2-methylbut-3-en-1-ol <=> (3R)-3,4-Epoxy-3-methylbut-1-ene + Glutathione
Acetyl-CoA + 3 Malonyl-CoA + Acyl-carrier protein <=> Orsellinate-[acp] + 4 CoA + 3 CO2 + H2O
S-Adenosyl-L-methionine + Orsellinate-[acp] <=> S-Adenosyl-L-homocysteine + 2-Methoxyorsellinate-[acp]
2-Methoxyorsellinate-[acp] + Iodide <=> 5-Iodo-2-methoxyorsellinate-[acp]
5-Iodo-2-methoxyorsellinate-[acp] <=> 3-Hydroxy-5-iodo-2-methoxyorsellinate-[acp]
S-Adenosyl-L-methionine + 3-Hydroxy-5-iodo-2-methoxyorsellinate-[acp] <=> S-Adenosyl-L-homocysteine + 5-Iodo-2,3-dimethoxyorsellinate-[acp]
dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Calicheamicinone <=> dTDP + Calicheamicin T0
dTDP-4-deoxy-4-thio-alpha-D-digitoxose + Calicheamicin T0 <=> dTDP + 4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin T0
4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin T0 + 5-Iodo-2,3-dimethoxyorsellinate-[acp] <=> Calicheamicin PsAg + Acyl-carrier protein
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin PsAg <=> dTDP + Calicheamicin alpha1(I)
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin alpha3(I) <=> dTDP + Calicheamicin gamma(1)I
dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin alpha1(I) <=> dTDP + Calicheamicin gamma(1)I
dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin PsAg <=> dTDP + Calicheamicin alpha3(I)
3-Hydroxy-4-methylanthranilyl-[aryl-carrier protein] + NADH + H+ + Oxygen <=> 3,5-Dihydroxy-4-methylanthranilyl-[aryl-carrier protein] + NAD+ + H2O
[F-actin]-L-methionine + NADPH + Oxygen + H+ <=> [F-actin]-L-methionine-(R)-S-oxide + NADP+ + H2O
(2S,3R)-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+
(2S,3S)-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+
cis-4-Hydroxy-D-proline + Acceptor <=> 1-Pyrroline-4-hydroxy-2-carboxylate + Reduced acceptor
D-Mannose 1-phosphate <=> NDP-D-mannose
NDP-D-mannose <=> NDP-4-oxo-6-deoxy-D-mannose
NDP-4-oxo-6-deoxy-D-mannose <=> NDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose
NDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose <=> NDP-2-amino-4-oxo-2,6-dideoxy-D-galactose
NDP-2-amino-4-oxo-2,6-dideoxy-D-galactose <=> NDP-2-amino-2,6-dideoxy-D-galactose
NDP-2-amino-2,6-dideoxy-D-galactose <=> NDP-2-methylamino-2,6-dideoxy-D-galactose
8 Malonyl-CoA + 7 NADPH + 7 H+ + Acyl-carrier protein <=> 3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] + 8 CoA + 8 CO2 + 6 H2O + 7 NADP+
3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] <=> 1,3,5,7,9,11,13-Pentadecaheptaene + CO2 + Acyl-carrier protein
Phosphoenolpyruvate + D-Mannose 6-phosphate + H2O <=> 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate + Orthophosphate
3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate + H2O <=> 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate + Orthophosphate
CTP + 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate <=> Diphosphate + CMP-3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate
(E)-4-Hydroxyphenylacetaldehyde oxime <=> (Z)-4-Hydroxyphenylacetaldehyde oxime
L-Leucyl-tRNA + L-Lysyl-protein <=> tRNA(Leu) + L-Leucyl-L-lysyl-protein
L-Leucyl-tRNA + L-Arginyl-protein <=> tRNA(Leu) + L-Leucyl-L-arginyl-protein
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine <=> (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O
(-)-Jasmonic acid + NADPH + H+ + Oxygen <=> trans-12-Hydroxyjasmonic acid + NADP+ + H2O
tert-Butyl alcohol + NADPH + H+ + Oxygen <=> 2-Methylpropane-1,2-diol + NADP+ + H2O
Butane + NADH + H+ + Oxygen <=> 1-Butanol + NAD+ + H2O
Tetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxytetracycline + NADP+ + H2O
Eicosanoyl-CoA + 4 Methylmalonyl-CoA + 8 NADPH + 8 H+ + Acyl-carrier protein <=> C32-Mycocerosyl-[acp] + 5 CoA + 4 CO2 + 8 NADP+ + 4 H2O
Stearoyl-CoA + 3 Methylmalonyl-CoA + 6 NADPH + 6 H+ + Acyl-carrier protein <=> C27-Mycolipanoyl-[acp] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O
S-Adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose <=> S-Adenosyl-L-homocysteine + dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-D-glucose
S-Adenosyl-L-methionine + dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-D-glucose <=> S-Adenosyl-L-homocysteine + dTDP-D-forosamine
EDTA + Reduced FMN + Oxygen <=> Ethylenediaminetriacetic acid + Glyoxylate + FMN + H2O
Ethylenediaminetriacetic acid + Reduced FMN + Oxygen <=> Ethylenediamine-N,N'-diacetic acid + Glyoxylate + FMN + H2O
EDTA + 2 Reduced FMN + 2 Oxygen <=> Ethylenediamine-N,N'-diacetic acid + 2 Glyoxylate + 2 FMN + 2 H2O
Dimethyl sulfone + Reduced FMN + Oxygen <=> Methanesulfinic acid + Formaldehyde + FMN + H2O
Vitamin D3 + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Calcidiol + 2 Oxidized ferredoxin + H2O
Calcidiol + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Calcitriol + 2 Oxidized ferredoxin + H2O
ATP + L-Erythrulose <=> ADP + Erythrulose 1-phosphate
ATP + D-Erythrulose <=> ADP + D-Erythrulose 4-phosphate
Isocaproyl-CoA + (R)-2-Hydroxyisocaproate <=> Isocaproate + (R)-2-Hydroxyisocaproyl-CoA
2-Amino-2-deoxyisochorismate + H2O <=> (5S,6S)-6-Amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate + Pyruvate
dTDP-4-oxo-5-C-methyl-L-rhamnose <=> dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose
dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose <=> dTDP-4-dimethylamino-4,6-dideoxy-5-C-methyl-D-allose
dTDP-4-oxo-alpha-D-xylose <=> dTDP-3-methyl-4-oxo-alpha-D-ribopyranose
dTDP-3-methyl-4-oxo-alpha-D-ribopyranose <=> dTDP-madurosamine
dTDP-4-amino-4,6-dideoxy-D-glucose + Reduced ferredoxin + Oxygen <=> dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Oxidized ferredoxin + H2O
S-Adenosyl-L-methionine + dTDP-L-rhamnose <=> S-Adenosyl-L-homocysteine + dTDP-3-O-methyl-beta-L-rhamnose
dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-deoxy-4-thio-alpha-D-digitoxose
dTDP-glucose + 2 NAD+ + H2O <=> dTDP-D-glucuronate + 2 NADH + 2 H+
dTDP-D-glucuronate + NAD+ <=> dTDP-4-oxo-alpha-D-xylose + CO2 + NADH + H+
dTDP-4-oxo-alpha-D-xylose <=> dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + H2O
dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + NADPH + H+ <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + NADP+
dTDP-4-amino-2,4-dideoxy-beta-L-xylose + 2-Oxoglutarate <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + L-Glutamate
S-Adenosyl-L-methionine + dTDP-4-amino-2,4-dideoxy-beta-L-xylose <=> S-Adenosyl-L-homocysteine + dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose
tert-Amyl alcohol + NADPH + H+ + Oxygen <=> Isoprenyl alcohol + NADP+ + 2 H2O
Tetracycline + FADH2 + Cl- + Oxygen + H+ <=> Chlortetracycline + FAD + 2 H2O
Acetyl-CoA + 2-Aminoethylphosphonate <=> 2-Acetamidoethylphosphonate + CoA
2-Acetamidoethylphosphonate <=> N-Ethylacetamide
Bialaphos <=> L-Phosphinothricin
4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (4aS,10bR)-Noroxomaritidine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (4aR,10bS)-Noroxomaritidine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
S-Adenosyl-L-methionine + Bacteriochlorophyllide c + H2O <=> 7-(Hydroxymethyl)bacteriochlorophyllide c + 5'-Deoxyadenosine + L-Methionine
Reduced flavodoxin + NADP+ <=> Oxidized flavodoxin + NADPH + H+
2 Glyphosate + Oxygen <=> 2 1-Aminomethylphosphonic acid + 2 Glyoxylate
Sulfite + Quinone + H2O <=> Sulfate + Hydroquinone
Sulfite + Hydrogen sulfide + Quinone <=> Thiosulfate + Hydroquinone
(1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + Oxygen <=> (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1,6-dicarboxylate + Hydrogen peroxide
(1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1,6-dicarboxylate + Oxygen <=> (5aS)-5,5a-Dihydrophenazine-1,6-dicarboxylate + Hydrogen peroxide
(1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate + Oxygen <=> (10aS)-10,10a-Dihydrophenazine-1-carboxylate + Hydrogen peroxide
(1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate + Oxygen <=> 5,10-Dihydrophenazine-1-carboxylate + Hydrogen peroxide
2 (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + 2 H2O
Magnesium protoporphyrin monomethyl ester + 3 S-Adenosyl-L-methionine + H2O <=> Divinylprotochlorophyllide + 3 5'-Deoxyadenosine + 3 H2O
Juglone + H2O <=> Naphthalene-1,2,4,8-tetrol
2 Naphthalene-1,2,4,8-tetrol + Oxygen <=> 2 3,5-Dihydroxy-1,4-naphthoquinone + 2 H2O
GDP-valienol + Validamine 7-phosphate <=> Validoxylamine A 7'-phosphate + GDP
Valienone 7-phosphate <=> Valienol 7-phosphate
Valienol 7-phosphate <=> Valienol 1-phosphate
(2R,3S,4S)-Leucoanthocyanidin + NADP+ <=> (2R,3R)-Dihydroflavonol + NADPH + H+
1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + Hydrogen peroxide <=> Veratraldehyde + o-Methoxyphenol + Glycolaldehyde + H2O
2 (3,4-Dimethoxyphenyl)methanol + Hydrogen peroxide <=> 2 (3,4-Dimethoxyphenyl)methanol radical + 2 H2O
1-(4-Hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + Hydrogen peroxide <=> 4-Hydroxy-3-methoxy-benzaldehyde + o-Methoxyphenol + Glycolaldehyde + H2O
1,2-Dihydro-beta-NAD + H+ + Oxygen <=> NAD+ + Hydrogen peroxide
1,6-Dihydro-beta-NAD + H+ + Oxygen <=> NAD+ + Hydrogen peroxide
Bacteriochlorophyllide d <=> 3-Vinyl bacteriochlorophyllide d + H2O
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine
8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine
12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + H2O <=> 8-Ethyl-12-methylbacteriochlorophyllide d
8,12-Diethyl-3-vinylbacteriochlorophyllide d + H2O <=> 8,12-Diethylbacteriochlorophyllide d
12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + H2O <=> 12-Ethyl-8-propylbacteriochlorophyllide d
12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H2O <=> 12-Ethyl-8-isobutylbacteriochlorophyllide d
Geranylgeranyl diphosphate + Bacteriochlorophyllide a <=> Geranylgeranyl bacteriochlorophyllide a + Diphosphate
ATP + Malonyl-[acyl-carrier protein] + L-Glutamine + H2O <=> AMP + Diphosphate + Malonamoyl-[acyl-carrier protein] + L-Glutamate
Malonamoyl-[acyl-carrier protein] + 8 Malonyl-CoA <=> 18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + 8 CO2 + 8 CoA
Bacteriochlorophyllide b + Geranylgeranyl diphosphate <=> Geranylgeranyl bacteriochlorophyllide b + Diphosphate
Geranylgeranyl bacteriochlorophyllide b + 3 NADPH + 3 H+ <=> Bacteriochlorophyll b + 3 NADP+
Protochlorophyllide + 2 Oxidized ferredoxin <=> Divinylprotochlorophyllide + 2 Reduced ferredoxin + 2 H+
S-Adenosyl-L-methionine + 4-Amino-anhydrotetracycline <=> S-Adenosyl-L-homocysteine + 4-Methylamino-4-de(dimethylamino)anhydrotetracycline
S-Adenosyl-L-methionine + 4-Methylamino-4-de(dimethylamino)anhydrotetracycline <=> S-Adenosyl-L-homocysteine + Anhydrotetracycline
Fe-coproporphyrin III + 2 Hydrogen peroxide <=> Heme + 2 CO2 + 4 H2O
[Sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine <=> [Sulfur-carrier protein]-Gly-Gly-L-Cys
[Sulfur-carrier protein]-Gly-Gly-L-Cys + H2O <=> L-Cysteine + Sulfur-carrier protein
Oxytetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxyoxytetracycline + NADP+ + H2O
Chlortetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxy-7-chlortetracycline + NADP+ + H2O
1-Acyl-sn-glycerol 3-phosphate + H2O <=> 1-Acylglycerol + Orthophosphate
L-Cysteine + [Protein]-L-cysteine <=> L-Alanine + [Protein]-S-sulfanyl-L-cysteine
[Enzyme]-S-sulfanylcysteine + [Protein]-L-cysteine <=> [Enzyme]-cysteine + [Protein]-S-sulfanyl-L-cysteine
ADP-glucose + D-Glucose 1-phosphate <=> ADP + alpha-Maltose 1-phosphate
Bacteriochlorophyllide g + 2 Oxidized ferredoxin + ADP + Orthophosphate <=> Divinyl chlorophyllide a + 2 Reduced ferredoxin + ATP + H2O + 2 H+
2-Aminomuconate + H2O <=> 2-Hydroxymuconate + Ammonia
S-Adenosyl-L-methionine + Phenazine-1-carboxylate + H+ <=> S-Adenosyl-L-homocysteine + 5-Methylphenazine-1-carboxylate
S-Adenosyl-L-methionine + N-Demethylindolmycin <=> S-Adenosyl-L-homocysteine + Indolmycin
ADP + alpha-D-Ribose 1-phosphate <=> AMP + D-Ribose 1,5-bisphosphate
ATP + Erythritol <=> ADP + D-Erythritol 1-phosphate
ATP + 17-(4-Hydroxyphenyl)heptadecanoate <=> Diphosphate + 17-(4-Hydroxyphenyl)heptadecanoyl adenylate
ATP + 19-(4-Hydroxyphenyl)nonadecanoate <=> Diphosphate + 19-(4-Hydroxyphenyl)nonadecanoyl adenylate
Lithocholoyl-CoA + Cholic acid <=> Lithocholic acid + Choloyl-CoA
Poly(ethylene terephthalate)(n) + H2O <=> Poly(ethylene terephthalate)(n-1) + 4-(2-Hydroxyethoxycarbonyl)benzoate
4-(2-Hydroxyethoxycarbonyl)benzoate + H2O <=> Terephthalate + Ethylene glycol
(2-Aminobenzoyl)acetyl-CoA + H2O <=> (2-Aminobenzoyl)acetate + CoA
Sulfoquinovosyldiacylglycerol + H2O <=> Sulfoquinovose + 1,2-Diacyl-sn-glycerol
beta-1,2-Mannotriose + H2O <=> beta-1,2-Mannobiose + alpha-D-Mannose
S-Adenosyl-L-methionine + (-)-5'-Demethylyatein <=> S-Adenosyl-L-homocysteine + Dihydroanhydropodorhizol
S-Adenosyl-L-methionine + Methanethiol <=> S-Adenosyl-L-homocysteine + Dimethyl sulfide
L-Leucyl-tRNA + L-Glutamyl-protein <=> tRNA(Leu) + L-Leucyl-L-glutamyl-protein
L-Leucyl-tRNA + L-Aspartyl-protein <=> tRNA(Leu) + L-Leucyl-L-aspartyl-protein
Feruloyl-CoA + 2-Oxoglutarate + Oxygen <=> 6-Hydroxyferuloyl-CoA + Succinate + CO2
6-Hydroxyferuloyl-CoA <=> Scopoletin + CoA
Geranyl diphosphate + H2O <=> Geranyl phosphate + Orthophosphate
Geranyl phosphate + H2O <=> Geraniol + Orthophosphate
ATP + D-Ribose 5-phosphate <=> Diphosphate + ADP-ribose
ATP + 3-Hydroxy-4-methylanthranilate <=> Diphosphate + (3-Hydroxy-4-methylanthranilyl)adenylate
Phosphatidylethanolamine + KDO2-lipid A <=> Diacylglycerol + Kdo2-lipid A 1-(2-aminoethyl diphosphate)
Phosphatidylethanolamine + KDO2-lipid A <=> Diacylglycerol + Kdo2-lipid A 4'-(2-aminoethyl diphosphate)
Phosphatidylethanolamine + Kdo2-lipid A 1-(2-aminoethyl diphosphate) <=> Diacylglycerol + Kdo2-lipid A 1,4'-bis(2-aminoethyl diphosphate)
CDP-glycerol + N-Acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol <=> CMP + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia
L-Glutaminyl-peptide + H2O <=> L-Glutamyl-protein + Ammonia
N5-Phenyl-L-glutamine + H2O <=> L-Glutamate + Aniline
Protein Nomega-(1-hydroxy-2-oxopropyl)-L-arginine + H2O <=> Protein-L-arginine + Lactate
Protein N6-(1-hydroxy-2-oxopropyl)-L-lysine + H2O <=> Protein lysine + Lactate
Protein S-(1-hydroxy-2-oxopropyl)-L-cysteine + H2O <=> [Protein]-L-cysteine + Lactate
7alpha,12alpha-Dihydroxy-3-oxochol-4-en-24-oyl-CoA <=> 12alpha-Hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O
7alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA <=> 3-Oxochola-4,6-dien-24-oyl-CoA + H2O
2 (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate + H2O
(1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate <=> (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + H2O
(1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + Oxygen <=> (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate + Hydrogen peroxide + CO2
(1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate <=> (1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate
(1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate + Oxygen <=> 5,10-Dihydrophenazine + Hydrogen peroxide + CO2
5,10-Dihydrophenazine + Oxygen <=> Phenazine + Hydrogen peroxide
(5aS)-5,5a-Dihydrophenazine-1,6-dicarboxylate <=> 5,10-Dihydrophenazine-1,6-dicarboxylate
5,10-Dihydrophenazine-1,6-dicarboxylate + Oxygen <=> Phenazine-1,6-dicarboxylic acid + Hydrogen peroxide
(10aS)-10,10a-Dihydrophenazine-1-carboxylate <=> 5,10-Dihydrophenazine-1-carboxylate
5,10-Dihydrophenazine-1-carboxylate + Oxygen <=> Phenazine-1-carboxylate + Hydrogen peroxide
Phenazine-1-carboxylate + NADH + Oxygen + H+ <=> 1-Hydroxyphenazine + NAD+ + CO2 + H2O
Heme + 6 Reduced ferredoxin + 3 Oxygen + 6 H+ <=> Biliverdin + Fe2+ + CO + 6 Oxidized ferredoxin + 3 H2O
S-Adenosyl-L-methionine + Cobalt-factor III + Reduced acceptor <=> S-Adenosyl-L-homocysteine + Cobalt-precorrin 4 + Acceptor
Molybdoenzyme molybdenum cofactor + GTP <=> Guanylyl molybdenum cofactor + Diphosphate
Molybdoenzyme molybdenum cofactor + CTP <=> Cytidylyl molybdenum cofactor + Diphosphate
Molybdoenzyme molybdenum cofactor + L-Cysteine + Reduced acceptor + H+ <=> Thio-molybdenum cofactor + L-Alanine + H2O + Acceptor
2-Methylpropanoyl-CoA + 3 Malonyl-CoA <=> 4 CoA + 3 CO2 + Phlorisobutyrophenone
Tetrachlorohydroquinone + NAD+ <=> Chloranil + NADH + H+
Anthraniloyl-CoA + L-Cysteinyl-protein <=> S-Anthraniloyl-L-cysteinyl-protein + CoA
S-Anthraniloyl-L-cysteinyl-protein + Malonyl-CoA <=> (2-Aminobenzoyl)acetyl-CoA + CO2 + S-Anthraniloyl-L-cysteinyl-protein
Anthraniloyl-CoA + Malonyl-CoA <=> (2-Aminobenzoyl)acetyl-CoA + CoA + CO2
S-Octanoyl-L-cysteinyl-protein + (2-Aminobenzoyl)acetate <=> 1-(2-Aminophenyl)decane-1,3-dione + CO2 + L-Cysteinyl-protein
1-(2-Aminophenyl)decane-1,3-dione <=> 2-Heptyl-4(1H)-quinolone + H2O
(R)-Lactate + Quinone <=> Pyruvate + Hydroquinone
Ribonucleoside triphosphate + Formate <=> Deoxynucleoside triphosphate + CO2 + H2O
Pyruvate + (R)-2-Hydroxyglutarate <=> (R)-Lactate + 2-Oxoglutarate
L-Proline + 2-Oxoglutarate + Oxygen <=> cis-4-Hydroxy-L-proline + Succinate + CO2
S-Adenosyl-L-methionine + (S)-Reticuline <=> S-Adenosyl-L-homocysteine + (S)-Tembetarine
(E)-2-Methylbutanal oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(E)-2-Methylpropanal oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Acetone cyanohydrin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + alpha-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
4-Trimethylammoniobutanoyl-CoA + Electron-transferring flavoprotein <=> (E)-4-(Trimethylammonio)but-2-enoyl-CoA + Reduced electron-transferring flavoprotein
GDP-L-fucose + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> GDP + alpha-L-Fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R
Geranyl diphosphate + Umbelliferone <=> Diphosphate + 8-Geranylumbelliferone
Geranyl diphosphate + Esculetin <=> Diphosphate + 8-Geranylesculetin
L-Arginine + H2O + Oxygen <=> 5-Guanidino-2-oxopentanoate + Ammonia + Hydrogen peroxide
Sulfite + Hydrogen sulfide + 2 Ferricytochrome c3 <=> Thiosulfate + 2 Ferrocytochrome c3
3-Aminobutanoyl-CoA + 2-Oxoglutarate <=> Acetoacetyl-CoA + L-Glutamate
ATP + 4-Hydroxybenzoate <=> Diphosphate + 4-Hydroxybenzoyl-adenylate
Dimethylallyl diphosphate + 2-Acylphloroglucinol <=> Diphosphate + 2-Acyl-4-prenylphloroglucinol
Dimethylallyl diphosphate + 2-Acyl-4-prenylphloroglucinol <=> Diphosphate + 2-Acyl-4,6-bisprenylphloroglucinol
Dimethylallyl diphosphate + 2-Acyl-4,6-bisprenylphloroglucinol <=> Diphosphate + 2-Acyl-4,6,6-trisprenylcyclohexa-2,4-dien-1-one
CDP-glycerol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> CMP + 4-O-Di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
CDP-ribitol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> CMP + 4-O-[1-D-Ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
n CDP-ribitol + 4-O-[1-D-Ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n CMP + 4-O-[(1-D-Ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
4-Hydroxybenzoyl-[acp] + 8 Malonyl-CoA + 16 NADPH + 16 H+ <=> 17-(4-Hydroxyphenyl)heptadecanoyl-[acp] + 8 CO2 + 8 CoA + 16 NADP+ + 8 H2O
4-Hydroxybenzoyl-[acp] + 9 Malonyl-CoA + 18 NADPH + 18 H+ <=> 19-(4-Hydroxyphenyl)nonadecanoyl-[acp] + 9 CO2 + 9 CoA + 18 NADP+ + 9 H2O
Oxamate + H2O <=> Oxalate + Ammonia
Alditol + Oxygen <=> Aldose + Hydrogen peroxide
3',5'-Cyclic AMP + H2O <=> 3',5'-Cyclic IMP + Ammonia
D-Sorbitol + Oxygen <=> alpha-D-Glucose + Hydrogen peroxide
4-O-Di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + n CDP-ribitol <=> 4-O-(D-Ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + n CMP
Jasmonoyl-L-amino acid + H2O <=> (-)-Jasmonic acid + L-Amino acid
D-Tagatose 6-phosphate <=> D-Fructose 6-phosphate
D-Tagaturonate <=> D-Fructuronate
cis-3-Hydroxy-L-proline <=> 1-Pyrroline-2-carboxylate + H2O
Sirohydrochlorin + Nickel(2+) <=> Nickel-sirohydrochlorin + 2 H+
Nickel-sirohydrochlorin + 2 ATP + 2 L-Glutamine + 2 H2O <=> Nickel-sirohydrochlorin a,c-diamide + 2 ADP + 2 L-Glutamate + 2 Orthophosphate
ATP + Nickel-sirohydrochlorin a,c-diamide + 3 Reduced acceptor + H2O <=> ADP + Orthophosphate + 15,17(3)-Seco-F430-17(3)-acid + 3 Acceptor
15,17(3)-Seco-F430-17(3)-acid + ATP <=> Coenzyme F430 + ADP + Orthophosphate
(-)-Betonicine <=> Turicine
Stachydrine <=> D-Proline betaine
ATP + L-Carnitine + CoA <=> AMP + Diphosphate + L-Carnitinyl-CoA
GTP + Formate <=> dGTP + CO2 + H2O
ATP + Formate <=> dATP + CO2 + H2O
UTP + Formate <=> dUTP + CO2 + H2O
CTP + Formate <=> dCTP + CO2 + H2O
Galactitol + NAD+ <=> L-Tagatose + NADH + H+
D-Altritol + NAD+ <=> D-Tagatose + NADH + H+
(Z)-2-Methylbutanal oxime <=> 2-Methylbutanenitrile + H2O
2-Methylbutanenitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + [Oxidized NADPH---hemoprotein reductase] + H2O
(Z)-2-Methylpropanal oxime <=> Isobutyronitrile + H2O
Isobutyronitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Acetone cyanohydrin + [Oxidized NADPH---hemoprotein reductase] + H2O
(9Z,12Z)-Hexadeca-9,12-dienoyl-CoA + Reduced acceptor + Oxygen <=> (9Z,12Z)-Hexadeca-9,12,15-trienoyl-CoA + Acceptor + 2 H2O
Linoleoyl-[glycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Pinolenoyl-[glycerolipid] + 2 Ferricytochrome b5 + 2 H2O
alpha-Linolenoyl-[glycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Coniferonoyl-[glycerolipid] + 2 Ferricytochrome b5 + 2 H2O
L-Polyhomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> omega-(Methylthio)-(E)-alkanal oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
L-Polyhomomethionine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> L-N-Hydroxypolyhomomethionine + [Oxidized NADPH---hemoprotein reductase] + H2O
L-N-Hydroxypolyhomomethionine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> L-N,N-Dihydroxypolyhomomethionine + [Oxidized NADPH---hemoprotein reductase] + H2O
L-N,N-Dihydroxypolyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime + CO2 + H2O
omega-(Methylthio)-(E)-alkanal oxime + [Reduced NADPH---hemoprotein reductase] + Glutathione + Oxygen <=> (E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
omega-(Methylthio)-(E)-alkanal oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 1-aci-Nitro-omega-(methylthio)alkane + [Oxidized NADPH---hemoprotein reductase] + H2O
1-aci-Nitro-omega-(methylthio)alkane + Glutathione <=> (E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O
Phenol + FADH2 + Oxygen <=> Catechol + FAD + H2O
Menaquinone-9 + Reduced acceptor <=> beta-Dihydromenaquinone-9 + Acceptor
N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate + NAD+ + H2O <=> 2-Oxoglutarate + L-2,3-Diaminopropanoate + NADH + H+
(+)-Sandaracopimaradiene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Sandaracopimaradien-3beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Sandaracopimaradien-3beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Oryzalexin E + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Sandaracopimaradien-3beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Oryzalexin D + [Oxidized NADPH---hemoprotein reductase] + H2O
2-(Glutathione-S-yl)-hydroquinone + Glutathione <=> Glutathione disulfide + Hydroquinone
Chitin(n+m) + Reduced acceptor + Oxygen <=> [(1->4)-N-Acetyl-beta-D-glucosaminyl]n-(1->4)-N-acetyl-2-deoxy-2-amino-D-glucono-1,5-lactone + Chitin(m) + Acceptor + H2O
2-Methyl-3-n-amyl-dihydropyrrole + FAD <=> 2-Methyl-3-n-amyl-pyrrole + FADH2
4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Methyl-3-n-amyl-pyrrole + ATP <=> Prodigiosin + ADP + Orthophosphate
4-Keto-2-undecylpyrroline + NADPH + H+ <=> 2-Undecylpyrrole + NADP+ + H2O
Dodecanoic acid + Malonyl-CoA + Glycine <=> 4-Keto-2-undecylpyrroline + 2 H2O + 2 CO2 + CoA
Pyrrole-2-carbonyl-[pcp] + Acyl-carrier protein <=> Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Peptidyl-carrier protein
4-Keto-2-undecylpyrroline + NADH + H+ <=> 2-Undecylpyrrole + NAD+ + H2O
Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Malonyl-CoA + L-Serine <=> 4-Hydroxy-2,2'-bipyrrole-5-methanol + CoA + Acyl-carrier protein + 2 CO2 + H2O
4-Hydroxy-2,2'-bipyrrole-5-methanol + NADP+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADPH + H+
4-Hydroxy-2,2'-bipyrrole-5-methanol + NAD+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADH + H+
4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + S-Adenosyl-L-methionine <=> 4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + S-Adenosyl-L-homocysteine
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]
(S)-3-Acetyloctanal + Amino acid <=> 2-Methyl-3-n-amyl-dihydropyrrole + 2-Oxo acid
4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Undecylpyrrole + ATP <=> Undecylprodigiosin + ADP + Orthophosphate
Dihydrocaffeoyl-CoA + 2 NAD+ + 2 Reduced ferredoxin <=> Caffeoyl-CoA + 2 NADH + 2 Oxidized ferredoxin
Butanoyl-CoA + 2 NAD+ + 2 Reduced ferredoxin <=> Crotonoyl-CoA + 2 NADH + 2 Oxidized ferredoxin
Lactate + 2 NAD+ + 2 Reduced ferredoxin <=> Pyruvate + 2 NADH + 2 Oxidized ferredoxin
(2S)-3-Sulfolactaldehyde + NAD+ + H2O <=> (S)-3-Sulfolactate + NADH + H+
(2S)-3-Sulfolactaldehyde + NADP+ + H2O <=> (S)-3-Sulfolactate + NADPH + H+
L-2-Aminoadipate 6-semialdehyde + NADP+ + AMP + Diphosphate <=> L-2-Aminoadipate + NADPH + H+ + ATP
1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate
Deacetylisoipecoside + S-Adenosyl-L-methionine <=> 6-O-Methyldeacetylisoipecoside + S-Adenosyl-L-homocysteine
6-O-Methyldeacetylisoipecoside + H2O <=> D-Glucose + 6-O-Methyl-N-deacetylisoipecoside aglycon
6-O-Methyl-N-deacetylisoipecoside aglycon <=> Protoemetine
Protoemetine + Dopamine <=> 7'-O-Dmethylcephaeline + H2O
7'-O-Dmethylcephaeline + S-Adenosyl-L-methionine <=> Cephaeline + S-Adenosyl-L-homocysteine
Cephaeline + S-Adenosyl-L-methionine <=> Emetine + S-Adenosyl-L-homocysteine
(S)-N-Methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-1-Hydroxy-N-methylcanadine + [Oxidized NADPH---hemoprotein reductase] + H2O
(S)-1-Hydroxy-N-methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (13S,14R)-1,13-Dihydroxy-N-methylcanadine + [Oxidized NADPH---hemoprotein reductase] + H2O
(13S,14R)-1,13-Dihydroxy-N-methylcanadine + Acetyl-CoA <=> (13S,14R)-1-Hydroxy-13-O-acetyl-N-methylcanadine + CoA
(13S,14R)-1-Hydroxy-13-O-acetyl-N-methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (13S,14R)-1,8-Dihydroxy-13-O-acetyl-N-methylcanadine + [Oxidized NADPH---hemoprotein reductase] + H2O
(13S,14R)-1,8-Dihydroxy-13-O-acetyl-N-methylcanadine <=> 4'-O-Desmethyl-3-O-acetylpapaveroxine + H+
4'-O-Desmethyl-3-O-acetylpapaveroxine + S-Adenosyl-L-methionine <=> 3-O-Acetylpapaveroxine + S-Adenosyl-L-homocysteine
3-O-Acetylpapaveroxine + H2O <=> Papaveroxine + Acetate
4'-O-Desmethyl-3-O-acetylpapaveroxine + H2O <=> 4'-O-Desmethylpapaveroxine + Acetate
4'-O-Desmethylpapaveroxine <=> Narcotoline hemiacetal
Narcotoline hemiacetal + NAD+ <=> Narcotoline + NADH + H+
2 S-Adenosyl-L-methionine + 3-(Aminomethyl)indole <=> 2 S-Adenosyl-L-homocysteine + Gramine
S-Adenosyl-L-methionine + 3-(Aminomethyl)indole <=> S-Adenosyl-L-homocysteine + (1H-Indol-3-yl)-N-methylmethanamine
S-Adenosyl-L-methionine + (1H-Indol-3-yl)-N-methylmethanamine <=> S-Adenosyl-L-homocysteine + Gramine
2 S-Adenosyl-L-methionine + Heme + 2 Reduced flavodoxin <=> S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + Anaerobilin + Fe2+ + 2 Oxidized flavodoxin
Acetyl-CoA + (3S)-3,6-Diaminohexanoate <=> CoA + (3S)-6-Acetamido-3-aminohexanoate
GDP-mannose + 1-Phosphatidyl-D-myo-inositol <=> GDP + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol
GDP-mannose + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol <=> GDP + 2,6-Di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
GDP-mannose + 2-O-(6-O-Acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol <=> GDP + 2-O-(6-O-Acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
O-Phospho-L-serine + L-Glutamate <=> N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate + Orthophosphate
ATP + 3-Dehydro-L-erythronate <=> ADP + 3-Dehydro-4-phospho-L-erythronate
ATP + 3-Dehydro-L-threonate <=> ADP + 3-Dehydro-4-phospho-D-erythronate
Acetyl-CoA + H2O + 3-Phosphonopyruvate <=> (R)-2-(Phosphonomethyl)malate + CoA
7-(Dihydroxymethyl)bacteriochlorophyllide c <=> Bacteriochlorophyllide e + H2O
2 S-Adenosyl-L-methionine + Bacteriochlorophyllide c + H2O <=> Bacteriochlorophyllide e + 2 5'-Deoxyadenosine + 2 L-Methionine
2 L-Arginine + 3 Reduced flavodoxin + 4 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + 3 Oxidized flavodoxin + 4 H2O
2 L-Arginine + 2 Reduced flavodoxin + 2 Oxygen <=> 2 N(omega)-Hydroxyarginine + 2 Oxidized flavodoxin + 2 H2O
2 N(omega)-Hydroxyarginine + Reduced flavodoxin + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + Oxidized flavodoxin + 2 H2O
UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminide <=> UDP + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-R
CMP-N-acetylneuraminate + beta-D-Galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R <=> CMP + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
3-Dehydro-4-phospho-L-erythronate <=> Glycerone phosphate + CO2
3-Dehydro-4-phospho-D-erythronate <=> Glycerone phosphate + CO2
Dihydroneopterin phosphate <=> 6-(Hydroxymethyl)-7,8-dihydropterin + Glycolaldehyde phosphate
7,8-Dihydroneopterin 3'-triphosphate <=> 6-(Hydroxymethyl)-7,8-dihydropterin + Glycolaldehyde triphosphate
Fructoselysine <=> Psicoselysine
2-Dehydro-L-erythronate <=> 3-Dehydro-L-erythronate
2-Dehydro-D-erythronate <=> 3-Dehydro-L-threonate
ATP + L-Isoleucine + Acetoacetyl-CoA <=> AMP + Diphosphate + Tenuazonic acid + CoA
4-Phospho-D-threonate + NAD+ <=> Glycerone phosphate + NADH + CO2 + H+
4-Phospho-D-erythronate + NAD+ <=> Glycerone phosphate + CO2 + NADH + H+
Indole-3-acetate + NADH + H+ + Oxygen <=> (2-Hydroxy-1H-indol-3-yl)acetate + NAD+ + H2O
(S)-Norreticuline + S-Adenosyl-L-methionine <=> (S)-Norlaudanine + S-Adenosyl-L-homocysteine
(E)-Phenylacetaldoxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Mandelonitrile + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Phenylacetonitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Mandelonitrile + [Oxidized NADPH---hemoprotein reductase] + H2O
Indole-3-acetaldehyde oxime + [Reduced NADPH---hemoprotein reductase] + Glutathione + Oxygen <=> S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Indole-3-acetaldehyde oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Indole-3-acetaldoxime N-oxide + [Oxidized NADPH---hemoprotein reductase] + H2O
Indole-3-acetaldoxime N-oxide + Glutathione <=> S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + H2O
(E)-Phenylacetaldoxime + [Reduced NADPH---hemoprotein reductase] + Glutathione + Oxygen <=> S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(E)-Phenylacetaldoxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 1-aci-Nitro-2-phenylethane + [Oxidized NADPH---hemoprotein reductase] + H2O
1-aci-Nitro-2-phenylethane + Glutathione <=> S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + H2O
(S)-Norlaudanine + S-Adenosyl-L-methionine <=> (S)-Tetrahydropapaverine + S-Adenosyl-L-homocysteine
Heme + 3 Reduced acceptor + 3 Oxygen <=> Mycobilin a + Fe2+ + 3 Acceptor + 3 H2O
Heme + 3 Reduced acceptor + 3 Oxygen <=> Mycobilin b + Fe2+ + 3 Acceptor + 3 H2O
Formylmethanofuran + 2 Oxidized ferredoxin + H2O <=> Methanofuran + 2 Reduced ferredoxin + CO2 + 2 H+
Hydroxylaminobenzene + 2 NADP+ + H2O <=> Nitrobenzene + 2 NADPH + 2 H+
Cellulose(n+m) + Reduced acceptor + Oxygen <=> [(1->4)-beta-D-Glucosyl]n-(1->4)-D-glucono-1,5-lactone + Cellulose(m) + Acceptor + H2O
Cellulose(n+m) + Reduced acceptor + Oxygen <=> 4-Dehydro-beta-D-glucosyl-[(1->4)-beta-D-glucosyl]n-1 + Cellulose(m) + Acceptor + H2O
(S)-Tetrahydropapaverine + 2 Oxygen <=> Papaverine + 2 Hydrogen peroxide
trans-Aconitate <=> Itaconate + CO2
Itaconate <=> 2-Hydroxyparaconate
Norcraugsodine + NADPH + H+ <=> Norbelladine + NADP+
Noroxopluviine <=> Caranine
Caranine <=> Lycorine
(4aR,10bS)-Noroxomaritidine <=> (4aR,10bS)-Normaritidine
(4aR,10bS)-Noroxomaritidine <=> Elwesine
(4aS,10bR)-Noroxomaritidine <=> Maritinamine
(4aS,10bR)-Noroxomaritidine <=> (-)-8-Demethylmaritidine
(-)-8-Demethylmaritidine <=> Vittatine
Vittatine <=> Haemanthamine
6-Lactoyl-5,6,7,8-tetrahydropterin <=> 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin
6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+
Tetrahydrobiopterin + NADP+ <=> 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADPH + H+
Tetrahydrobiopterin + NADP+ <=> 7,8-Dihydrobiopterin + NADPH + H+
6-Lactoyl-5,6,7,8-tetrahydropterin <=> Sepiapterin
Dihydrobiopterin <=> 7,8-Dihydrobiopterin
2,5-Dioxopentanoate + NAD+ + H2O <=> 2-Oxoglutarate + NADH + H+
3,4-Didehydroadipyl-CoA <=> 5-Carboxy-2-pentenoyl-CoA
2,4,6/3,5-Pentahydroxycyclohexanone + NAD+ <=> 3-Dehydro-scyllo-inosose + NADH + H+
3-Dehydro-scyllo-inosose + H2O <=> 5-Dehydro-L-gluconate
5-Dehydro-L-gluconate <=> D-Tagaturonate
Propanoyl-CoA + Succinate <=> Succinyl-CoA + Propanoate
(2R,3S)-2-Alkyl-3-hydroxyalkanoate + NADP+ <=> (R)-2-Alkyl-3-oxoalkanoate + NADPH + H+
(2R,3S)-2-Alkyl-3-hydroxyalkanoate + ATP <=> cis-3-Alkyl-4-alkyloxetan-2-one + AMP + Diphosphate
(3R,4R)-3-[(1S)-1-Hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP+ <=> (3R,4R)-3-Alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH + H+
16-Methoxy-2,3-dihydro-3-hydroxytabersonine + Acceptor <=> (3R)-3-Hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + Reduced acceptor
2 S-Adenosyl-L-methionine + 8-Amino-8-demethylriboflavin <=> 2 S-Adenosyl-L-homocysteine + Roseoflavin
S-Adenosyl-L-methionine + 8-Amino-8-demethylriboflavin <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(methylamino)riboflavin
S-Adenosyl-L-methionine + 8-Demethyl-8-(methylamino)riboflavin <=> S-Adenosyl-L-homocysteine + Roseoflavin
Acyl-CoA + 2,6-Di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol <=> CoA + 2-O-(6-O-Acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
Acyl-CoA + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol <=> CoA + 2-O-(6-O-Acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol
ADP-glucose + D-Glucose 6-phosphate <=> ADP + alpha,alpha'-Trehalose 6-phosphate
ATP + D-Threonate <=> ADP + 4-Phospho-D-threonate
N-Acetylmuramic acid 6-phosphate + H2O <=> N-Acetylmuramate + Orthophosphate
RNA terminal-2',3'-cyclic-phosphate + H2O <=> RNA 2'-terminal-phosphate
(+)-Kolavenyl diphosphate + H2O <=> (+)-Kolavelool + Diphosphate
Cyclobis-1,6-alpha-nigerosyl + 2 H2O <=> 2 Isomaltose
Cyclobis-1,6-alpha-nigerosyl + H2O <=> alpha-Isomaltosyl-1,3-isomaltose
alpha-Isomaltosyl-1,3-isomaltose + H2O <=> 2 Isomaltose
Isomaltose + H2O <=> beta-D-Glucose + D-Glucose
(E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O <=> (E)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-omega-(methylsulfanyl)alkane-1-imine + L-Glutamate
S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + H2O <=> (E)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethane-1-imine + L-Glutamate
(Glutathione-S-yl)(1H-indol-3-yl)acetonitrile + H2O <=> (L-Cysteinylglycine-S-yl)(1H-indol-3-yl)acetonitrile + L-Glutamate
S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + H2O <=> (Z)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-2-phenylethane-1-imine + L-Glutamate
3'-Phosphoadenylyl sulfate + 12-Hydroxyjasmonate <=> Adenosine 3',5'-bisphosphate + 12-Sulfooxyjasmonate
3 S-Adenosyl-L-methionine + Ornithine lipid <=> 3 S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid
S-Adenosyl-L-methionine + Ornithine lipid <=> S-Adenosyl-L-homocysteine + N-Methylornithine lipid
S-Adenosyl-L-methionine + N-Methylornithine lipid <=> S-Adenosyl-L-homocysteine + N,N-Dimethylornithine lipid
S-Adenosyl-L-methionine + N,N-Dimethylornithine lipid <=> S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] <=> Lyso-ornithine lipid + Acyl-carrier protein
(3R)-3-Hydroxy-2,3-dihydrotabersonine + Acceptor <=> (3R)-3-Hydroxy-1,2-didehydro-2,3-dihydrotabersonine + Reduced acceptor
ATP + D-Erythronate <=> ADP + 4-Phospho-D-erythronate
omega-(Methylthio)alkyl-glucosinolate + NADPH + H+ + Oxygen <=> omega-(Methylsulfinyl)alkyl-glucosinolate + NADP+ + H2O
Dimethylamine + NADPH + H+ + Oxygen <=> Methylamine + Formaldehyde + NADP+ + H2O
Jasmonoyl-L-amino acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Hydroxyjasmonoyl-L-amino acid + [Oxidized NADPH---hemoprotein reductase] + H2O
12-Hydroxyjasmonoyl-L-amino acid + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 12-Hydroxy-12-oxojasmonoyl-L-amino acid + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
12-Hydroxyjasmonoyl-L-amino acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Oxojasmonoyl-L-amino acid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
12-Oxojasmonoyl-L-amino acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Hydroxy-12-oxojasmonoyl-L-amino acid + [Oxidized NADPH---hemoprotein reductase] + H2O
16-Methoxytabersonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (3R)-3-Hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + [Oxidized NADPH---hemoprotein reductase] + H2O
Tabersonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (3R)-3-Hydroxy-1,2-didehydro-2,3-dihydrotabersonine + [Oxidized NADPH---hemoprotein reductase] + H2O
Butachlor + 2 Reduced ferredoxin + Oxygen <=> 2-Chloro-N-(2,6-diethylphenyl)acetamide + Butyl formate + 2 Oxidized ferredoxin + H2O
2-(L-Cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Camalexin + Hydrogen cyanide + CO2 + 2 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
2-(L-Cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (R)-Dihydrocamalexate + Hydrogen cyanide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(R)-Dihydrocamalexate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Camalexin + CO2 + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Heme + 3 Reduced acceptor + 3 Oxygen <=> Biliverdin-IX-delta + CO + Fe2+ + 3 Acceptor + 3 H2O
Heme + 3 Reduced acceptor + 3 Oxygen <=> Biliverdin-IX-beta + CO + Fe2+ + 3 Acceptor + 3 H2O
2 Formate + NAD+ + 2 Oxidized ferredoxin <=> 2 CO2 + NADH + H+ + 2 Reduced ferredoxin
Hydroxyproline <=> (S)-1-Pyrroline-5-carboxylate + H2O
ent-8alpha-Hydroxylabd-13-en-15-yl diphosphate <=> Geranylgeranyl diphosphate + H2O
Peregrinol diphosphate <=> Geranylgeranyl diphosphate + H2O
trans,trans-Farnesyl diphosphate + H2O <=> (+)-Isoafricanol + Diphosphate
Geranylgeranyl diphosphate <=> (-)-Spiroviolene + Diphosphate
Geranylgeranyl diphosphate <=> Tsukubadiene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (2S,3R,6S,9S)-(-)-Protoillud-7-ene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (3S)-(+)-Asterisca-2(9),6-diene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-alpha-Amorphene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-Corvol ether B + Diphosphate
trans,trans-Farnesyl diphosphate <=> (+)-Eremophilene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (1R,4R,5S)-(-)-Guaia-6,10(14)-diene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-(1E,4E,6S,7R)-Germacra-1(10),4-dien-6-ol + Diphosphate
Geranylgeranyl diphosphate + H2O <=> (3E,7E)-Dolabella-3,7-dien-18-ol + Diphosphate
Geranylgeranyl diphosphate <=> (3E,7E)-Dolathalia-3,7,11-triene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 7-epi-alpha-Eudesmol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 4-epi-Cubebol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-Corvol ether A + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-Juneol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> tau-Cadinol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (2E,6E)-Hedycaryol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-Cubebol + Diphosphate
all-trans-Pentaprenyl diphosphate + H2O <=> Sesterfisherol + Diphosphate
Geranyl diphosphate <=> beta-Thujene + Diphosphate
all-trans-Pentaprenyl diphosphate <=> Stellata-2,6,19-triene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Guaia-4,6-diene + Diphosphate
Geranylgeranyl diphosphate <=> Pseudolaratriene + Diphosphate
trans,trans-Farnesyl diphosphate <=> Selina-4(15),7(11)-diene + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (+)-(2S,3R,9R)-Pristinol + Diphosphate
Copalyl diphosphate + H2O <=> Nezukol + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> 5-Hydroxy-alpha-gurjunene + Diphosphate
ent-Copalyl diphosphate <=> ent-Atiserene + Diphosphate
ent-8alpha-Hydroxylabd-13-en-15-yl diphosphate <=> ent-13-epi-Manoyl oxide + Diphosphate
trans,trans-Farnesyl diphosphate + H2O <=> (2Z,6E)-Hedycaryol + Diphosphate
all-trans-Pentaprenyl diphosphate <=> beta-Geranylfarnesene + Diphosphate
all-trans-Hexaprenyl diphosphate <=> beta-Hexaprene + Diphosphate
all-trans-Heptaprenyl diphosphate <=> beta-Heptaprene + Diphosphate
Peregrinol diphosphate <=> (13R)-9,13-Epoxylabd-14-ene + Diphosphate
Copal-8-ol diphosphate <=> Manoyl oxide + Diphosphate
Geranylgeranyl diphosphate <=> Cycloaraneosene + Diphosphate
(13E)-Labda-7,13-dien-15-yl diphosphate <=> Labda-7,13(16),14-triene + Diphosphate
Copalyl diphosphate <=> (12E)-Labda-8(17),12,14-triene + Diphosphate
Glutathione <=> Cys-Gly + 5-Oxoproline
epsilon-(gamma-L-Glutamyl)-L-lysine <=> L-Lysine + 5-Oxoproline
S-(Hercyn-2-yl)-L-cysteine S-oxide + H2O <=> 2-(Hydroxysulfanyl)hercynine + Pyruvate + Ammonia
2-(Hydroxysulfanyl)hercynine + Reduced acceptor <=> Ergothioneine + Acceptor + H2O
Linalool <=> Geraniol
(3S,22S)-2,3:22,23-Diepoxy-2,3,22,23-tetrahydrosqualene <=> Pre-alpha-onocerin
Pre-alpha-onocerin <=> alpha-Onocerin
Geranylgeranyl diphosphate <=> (-)-Kolavenyl diphosphate
Geranylgeranyl diphosphate <=> (+)-Kolavenyl diphosphate
Geranylgeranyl diphosphate <=> (13E)-Labda-7,13-dien-15-yl diphosphate
ATP + 4-Hydroxybenzoate + Acyl-carrier protein <=> AMP + Diphosphate + 4-Hydroxybenzoyl-[acp]
4-Hydroxybenzoyl-adenylate + Acyl-carrier protein <=> AMP + 4-Hydroxybenzoyl-[acp]
Reduced coenzyme F420 + Methanophenazine <=> Coenzyme F420 + Dihydromethanophenazine
L-Carnitine + NADH + H+ + Oxygen <=> (3R)-3-Hydroxy-4-oxobutanoate + Trimethylamine + NAD+ + H2O
2 4-Sulfanylbutanoate + NAD+ <=> 4,4'-Disulfanediyldibutanoate + NADH + H+
(4R)-4,2'-Dihydroxyisoflavan + NADP+ <=> (3R)-2'-Hydroxyisoflavanone + NADPH + H+
[Sulfatase]-L-cysteine + Oxygen + 2 Thiol <=> [Sulfatase]-3-oxo-L-alanine + Hydrogen sulfide + Oxidized thiol-containing reductant + H2O
UDP-N-acetyl-alpha-D-glucosamine + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-R <=> UDP + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-R
4 Manganese(2+) + 2 Oxygen + 4 H2O <=> 4 Mn(IV)O2 + 8 H+
4 Manganese(2+) + Oxygen + 4 H+ <=> 4 Manganese(3+) + 2 H2O
4 Manganese(3+) + Oxygen + 6 H2O <=> 4 Mn(IV)O2 + 12 H+
2 Ubiquinol <=> 2 Ubiquinone + 4 H+ + 4 e-
Oxygen + 4 H+ + 4 e- <=> 2 H2O
3'-Phosphoadenylyl sulfate + 7-Methylthioheptyl-desulfoglucosinolate <=> Adenosine 3',5'-bisphosphate + 7-Methylthioheptyl glucosinolate
3'-Phosphoadenylyl sulfate + 8-Methylthiooctyl-desulfoglucosinolate <=> Adenosine 3',5'-bisphosphate + 8-Methylthiooctyl glucosinolate
Chitobiose + H2O <=> N-Acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + Acetate
Carmofur <=> 5-FU
ATP + 5-Fluorouridine monophosphate <=> ADP + 5-Fluorouridine diphosphate
ATP + 5-Fluorodeoxyuridine monophosphate <=> ADP + 5-Fluorodeoxyuridine diphosphate
5-Fluorodeoxyuridine diphosphate + Thioredoxin disulfide + H2O <=> 5-Fluorouridine diphosphate + Thioredoxin
ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate
ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate
5-Fluorodeoxyuridine triphosphate + H2O <=> 5-Fluorodeoxyuridine monophosphate + Diphosphate
Ethylene oxide + Coenzyme M <=> 2-Hydroxyethyl-CoM
2-Hydroxyethyl-CoM <=> Acetyl-CoA
Chloroethylene oxide + Coenzyme M <=> 2-Chloro-2-hydroxyethyl-CoM
2-Chloro-2-hydroxyethyl-CoM <=> Acetyl-CoA
Vinyl chloride + NADH + H+ + Oxygen <=> Chloroethylene oxide + NAD+ + H2O
Acetyl-CoA + Hydrazine <=> CoA + Acetylhydrazine
Acetylhydrazine + H2O <=> Hydrazine + Acetate
Acetylhydrazine + NADPH + H+ + Oxygen <=> Hepatotoxins + NADP+ + H2O
Hepatotoxins + Glutathione <=> R-S-Glutathione
Isoniazid + Hydrogen peroxide <=> Isonicotinoyl radical + Diimine + 2 H2O
Isonicotinoyl radical + NAD+ <=> Isonicotinoyl-NAD adduct
Isonicotinoyl radical + NADP+ <=> Isonicotinoyl-NADP adduct
L-Carnitine + NADPH + H+ + Oxygen <=> (3R)-3-Hydroxy-4-oxobutanoate + Trimethylamine + NADP+ + H2O
Tryptamine + Reduced acceptor + Oxygen <=> 4-Hydroxytryptamine + Acceptor + H2O
4,4'-Diapolycopen-4-al + H2O + Acceptor <=> 4,4'-Diapolycopen-4-oate + Reduced acceptor
4,4'-Diapolycopenedial + 2 H2O + 2 Acceptor <=> 4,4'-Diapolycopene-4,4'-dioate + 2 Reduced acceptor
Long-chain fatty acid + hn <=> Long-chain alkane + CO2
3,4-Dihydroxy-L-phenylalanine + Oxygen + H2O <=> 3,4-Dihydroxyphenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide
L-Tyrosine + Oxygen + H2O <=> 4-Hydroxyphenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide
L-Phenylalanine + Oxygen + H2O <=> Phenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide
Aminoimidazole ribotide + S-Adenosyl-L-methionine + Reduced acceptor <=> 5-Hydroxybenzimidazole + 5'-Deoxyadenosine + L-Methionine + Formate + Ammonia + Orthophosphate + Acceptor
Geranylgeranyl diphosphate <=> Rhizathalene A + Diphosphate
Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide <=> Pyridinium-3,5-bisthiocarboxylate mononucleotide + Nickel(2+)
ATP + 17-(4-Hydroxyphenyl)heptadecanoate + Acyl-carrier protein <=> AMP + Diphosphate + 17-(4-Hydroxyphenyl)heptadecanoyl-[acp]
17-(4-Hydroxyphenyl)heptadecanoyl adenylate + Acyl-carrier protein <=> AMP + 17-(4-Hydroxyphenyl)heptadecanoyl-[acp]
ATP + 19-(4-Hydroxyphenyl)nonadecanoate + Acyl-carrier protein <=> AMP + Diphosphate + 19-(4-Hydroxyphenyl)nonadecanoyl-[acp]
19-(4-Hydroxyphenyl)nonadecanoyl adenylate + Acyl-carrier protein <=> AMP + 19-(4-Hydroxyphenyl)nonadecanoyl-[acp]
ATP + L-Firefly luciferin + CoA <=> AMP + Diphosphate + L-Firefly luciferyl-CoA
[(3S,4R)-4-Alkanoyl-5-oxooxolan-3-yl]methyl phosphate + NADP+ <=> (4-Alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate + NADPH + H+
Coenzyme B + Coenzyme M + 2 Coenzyme F420 + 2 Reduced ferredoxin + 2 H+ <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Reduced coenzyme F420 + 2 Oxidized ferredoxin
Hydrogen sulfide + Glutathione + Quinone <=> S-Sulfanylglutathione + Hydroquinone
1-(4-Methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O <=> 2-({[(4-Methoxyphenyl)methyl](methyl)amino}methyl)-2-methylpropane-1,3-diol
Coenzyme B + Coenzyme M + 2 Oxidized ferredoxin <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Reduced ferredoxin + 2 H+
4-Hydroxy-L-tryptophan <=> 4-Hydroxytryptamine + CO2
ATP + 4-Hydroxytryptamine <=> ADP + Norbaeocystin
2 S-Adenosyl-L-methionine + Norbaeocystin <=> 2 S-Adenosyl-L-homocysteine + Psilocybin
S-Adenosyl-L-methionine + Norbaeocystin <=> S-Adenosyl-L-homocysteine + Baeocystin
S-Adenosyl-L-methionine + Baeocystin <=> S-Adenosyl-L-homocysteine + Psilocybin
GDP-mannose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> GDP + alpha-D-Mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
2 GDP-mannose + alpha-D-Mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> 2 GDP + alpha-D-Mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP-glucose + Mogrol <=> Mogroside IE + UDP
Dimethylallyl diphosphate + 3 Isopentenyl diphosphate <=> 3 Diphosphate + Nerylneryl diphosphate
ATP + L-Glutamine + H2O <=> AMP + Orthophosphate + N5-Phospho-L-glutamine
Oleuropein + H2O <=> Oleuropein aglycone + D-Glucose
Coenzyme B + Coenzyme M + 2 Reduced ferredoxin + 2 H+ <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Oxidized ferredoxin + 2 Hydrogen
Coenzyme B + Coenzyme M + 2 Reduced ferredoxin + 2 CO2 + 2 H+ <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Oxidized ferredoxin + 2 Formate
Ubiquinone + NADH + 6 H+ <=> Ubiquinol + NAD+ + 5 H+
S-Sulfanylglutathione + Oxygen <=> S-Sulfinatoglutathione
S-Sulfinatoglutathione + H2O <=> Glutathione + Sulfite
Ornithine lipid + 2-Oxoglutarate + Oxygen <=> 2-Hydroxyornithine lipid + Succinate + CO2
Nerolidol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (3E)-4,8-Dimethylnona-1,3,7-triene + But-3-en-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ATP + (-)-Jasmonic acid + L-Amino acid <=> AMP + Diphosphate + Jasmonoyl-L-amino acid
Ferruginol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Hydroxyferruginol + [Oxidized NADPH---hemoprotein reductase] + H2O
Retinol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> all-trans-3,4-Didehydroretinol + 2 Oxidized adrenal ferredoxin + 2 H2O
S-Adenosyl-L-methionine + Adenine in U6 snRNA <=> S-Adenosyl-L-homocysteine + N6-Methyladenine in U6 snRNA
S-Adenosyl-L-methionine + (+)-Kolavelool <=> S-Adenosyl-L-homocysteine + (+)-O-Methylkolavelool
Sesamin + Tetrahydrofolate <=> (+)-Demethylpiperitol + 5,10-Methylenetetrahydrofolate
(+)-Demethylpiperitol + Tetrahydrofolate <=> (+)-Didemethylpinoresinol + 5,10-Methylenetetrahydrofolate
Acetyl-CoA + Ethanol <=> CoA + Ethyl acetate
2 Acyl-CoA + H2O <=> (R)-2-Alkyl-3-oxoalkanoate + 2 CoA
2-O-(alpha-D-Glucopyranosyl)-D-glycerate + Orthophosphate <=> D-Glucose 1-phosphate + D-Glycerate
L-Glutamate + FMN + Oxygen + H2O + 3 Acceptor <=> 2-Oxoglutarate + 8-Amino-8-demethylriboflavin 5'-phosphate + CO2 + 3 Reduced acceptor
FMN + Oxygen <=> 8-Demethyl-8-formylriboflavin 5'-phosphate + H2O
8-Demethyl-8-formylriboflavin 5'-phosphate + H2O + Acceptor <=> 8-Carboxy-8-demethylriboflavin 5'-phosphate + Reduced acceptor
L-Glutamate + 8-Carboxy-8-demethylriboflavin 5'-phosphate + H2O + 2 Acceptor <=> 2-Oxoglutarate + 8-Amino-8-demethylriboflavin 5'-phosphate + CO2 + 2 Reduced acceptor
ATP + Rifampicin + H2O <=> AMP + 21-Phosphorifampicin + Orthophosphate
Wall teichoic acid + n H2O <=> Wall teichoic acid + n D-Alanine
[SoxY protein]-S-disulfanyl-L-cysteine + 6 Ferricytochrome c + 3 H2O <=> [SoxY protein]-S-sulfosulfanyl-L-cysteine + 6 Ferrocytochrome c + 6 H+
UDP-L-rhamnose + alpha-D-Galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl]n <=> UDP + [(1->2)-alpha-L-Rhamnosyl-(1->4)-alpha-D-galacturonosyl]n
11-Hydroxyferruginol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Carnosic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Ferruginol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Salviol + [Oxidized NADPH---hemoprotein reductase] + H2O
beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Maniladiol + [Oxidized NADPH---hemoprotein reductase] + H2O
beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Daturadiol + [Oxidized NADPH---hemoprotein reductase] + H2O
Ferruginol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Sugiol + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
ent-2alpha-Hydroxyisokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase]
11-Hydroxysugiol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11,20-Dihydroxysugiol + [Oxidized NADPH---hemoprotein reductase] + H2O
9beta-Pimara-7,15-diene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 9beta-Pimara-7,15-diene-3beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Cassa-12,15-diene + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> ent-3beta-Hydroxycassa-12,15-dien-2-one + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
ent-Cassa-12,15-diene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-dien-2beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Cassa-12,15-dien-2beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ent-Cassa-12,15-dien-2-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-3beta-Hydroxycassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Cassa-12,15-dien-2beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-diene-2beta,3beta-diol + [Oxidized NADPH---hemoprotein reductase] + H2O
ent-Cassa-12,15-diene-2beta,3beta-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-3beta-Hydroxycassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
11-Hydroxyferruginol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11,20-Dihydroxyferruginol + [Oxidized NADPH---hemoprotein reductase] + H2O
Sugiol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Hydroxysugiol + [Oxidized NADPH---hemoprotein reductase] + H2O
Ferruginol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Pisiferic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
11-Hydroxyferruginol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 11-Hydroxysugiol + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
(2R,3S,4S)-Leucoanthocyanidin + 2-Oxoglutarate + Oxygen <=> (4S)- 2,3-Dehydroflavan-3,4-diol + Succinate + CO2 + H2O
(4S)- 2,3-Dehydroflavan-3,4-diol + H+ <=> Anthocyanidin with a 3-hydroxy group + H2O
(2R,3S,4S)-Leucoanthocyanidin + 2-Oxoglutarate + Oxygen + H+ <=> Anthocyanidin with a 3-hydroxy group + Succinate + CO2 + 2 H2O
GDP-D-mannose + Triacylated phosphatidyl-myo-inositol dimannoside <=> GDP + Triacylated phosphatidyl-myo-inositol trimannoside
GDP-D-mannose + Tetraacylated phosphatidyl-myo-inositol dimannoside <=> GDP + Tetraacylated phosphatidyl-myo-inositol trimannoside
(S)-Lactate + Oxygen <=> Pyruvate + Hydrogen peroxide
beta-D-Mannosylphosphodecaprenol + Triacylated phosphatidyl-myo-inositol tetramannoside <=> Decaprenol phosphate + Triacylated phosphatidyl-myo-inositol pentamannoside
beta-D-Mannosylphosphodecaprenol + Tetraacylated phosphatidyl-myo-inositol tetramannoside <=> Decaprenol phosphate + Tetraacylated phosphatidyl-myo-inositol pentamannoside
cis-1,4-Polyisoprene + n Oxygen <=> n (4Z,8Z)-4,8-Dimethyl-12-oxotrideca-4,8-dienal
Siroheme <=> 12,18-Didecarboxysiroheme + 2 CO2
12,18-Didecarboxysiroheme <=> Fe-coproporphyrin III
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine <=> Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine
Lutein <=> meso-Zeaxanthin
3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> Hapalindole H
3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> 12-epi-Hapalindole U
3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> 12-epi-Fischerindole U
Cucurbitadienol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 11-Oxocucurbitadienol + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Cucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Hydroxycucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + H2O
11-Hydroxycucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Oxocucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(-)-Drimenol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Drimendiol + [Oxidized NADPH---hemoprotein reductase] + H2O
S-Adenosyl-L-methionine + Adenine in mRNA <=> S-Adenosyl-L-homocysteine + N6-Methyladenine in mRNA
GDP-6-deoxy-alpha-D-altrose + Sordaricin <=> 4'-O-Demethylsordarin + GDP
4-Hydroxybenzoate + 2 NADPH + 2 Bromide + 2 Oxygen + 4 H+ <=> 2,4-Dibromophenol + 2 NADP+ + CO2 + 4 H2O
n UDP-N-acetyl-alpha-D-glucosamine + 4-O-(D-Ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-(2-N-Acetyl-beta-D-glucosaminyl-D-ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
4-Hydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3-Bromo-4-hydroxybenzoate + NADP+ + 2 H2O
3-Bromo-4-hydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 2,4-Dibromophenol + NADP+ + CO2 + 2 H2O
Deamino-NAD+ + HCO3- <=> AMP + Pyridinium-3,5-biscarboxylic acid mononucleotide
3,4-Dihydroxybenzoate + 2 NADPH + 2 Bromide + 2 Oxygen + 4 H+ <=> 3,5-Dibromobenzene-1,2-diol + 2 NADP+ + CO2 + 4 H2O
3,4-Dihydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3-Bromo-4,5-dihydroxybenzoate + NADP+ + 2 H2O
3-Bromo-4,5-dihydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3,5-Dibromobenzene-1,2-diol + NADP+ + CO2 + 2 H2O
Pyrrole-2-carbonyl-[pcp] + FADH2 + Cl- + Oxygen <=> 5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Cl- + Oxygen <=> 4,5-Dichloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
Pyrrole-2-carbonyl-[pcp] + 2 FADH2 + 2 Cl- + 2 Oxygen <=> 4,5-Dichloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + 2 FAD + 4 H2O
N-(4-Oxoglutaryl)-L-cysteinylglycine + H2O <=> 2-Oxoglutarate + Cys-Gly
cis-3-[2,2-Dichloro-1-(4-chlorophenyl)vinyl]-6-chlorocyclohexa-3,5-diene-1,2-diol + NAD+ <=> 1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene + NADH + H+
NAD+ + Glycine + Hydrogen sulfide <=> Nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
Pyrrole-2-carbonyl-[pcp] + FADH2 + Bromide + Oxygen <=> 5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Bromide + Oxygen <=> 4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Bromide + Oxygen <=> 3,4,5-Tribromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O
Pyrrole-2-carbonyl-[pcp] + 3 FADH2 + 3 Bromide + 3 Oxygen <=> 3,4,5-Tribromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + 3 FAD + 6 H2O
L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 5-Chloro-L-tryptophan + FAD + 2 H2O
L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6-Chloro-L-tryptophan + FAD + 2 H2O
D-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6-Chloro-D-tryptophan + FAD + 2 H2O
7-Chloro-L-tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6,7-Dichloro-L-tryptophan + FAD + 2 H2O
Anthranilate + N,N-Dimethyl-1,4-phenylenediamine + 2 NAD+ <=> Methyl red + 2 NADH + 2 H+
n UDP-glucose + 4-O-[(1-D-Ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-[(2-beta-D-Glucosyl-1-D-ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
n UDP-N-acetyl-alpha-D-glucosamine + 4-O-(D-Ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-(2-N-Acetyl-alpha-D-glucosaminyl-D-ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
GDP-D-mannose + 1-Phosphatidyl-D-myo-inositol <=> GDP + Phosphatidyl-myo-inositol monomannoside
Acyl-CoA + Phosphatidyl-myo-inositol monomannoside <=> CoA + Triacylated phosphatidyl-myo-inositol monomannoside
GDP-D-mannose + Phosphatidyl-myo-inositol monomannoside <=> GDP + Phosphatidyl-myo-inositol dimannoside
GDP-D-mannose + Triacylated phosphatidyl-myo-inositol monomannoside <=> GDP + Triacylated phosphatidyl-myo-inositol dimannoside
Acyl-CoA + Phosphatidyl-myo-inositol dimannoside <=> CoA + Triacylated phosphatidyl-myo-inositol dimannoside
UDP-glucose + (E)-omega-(Methylthio)alkyl-thiohydroximate <=> UDP + Aliphatic desulfoglucosinolate
Kaempferol 3-O-glucoside + UDP-L-rhamnose <=> Kaempferol-3-O-rutinoside + UDP
Afzelin + UDP-glucose <=> Kaempferol 3-O-rhamnoside-7-O-glucoside + UDP
Stearoyl-CoA + NADPH + H+ + Oxygen <=> Oleoyl-CoA + NADP+ + 2 H2O
Anthraniloyl-CoA + 2 Malonyl-CoA <=> 2-Methylquinolin-4-ol + 3 CO2 + 3 CoA
2-Methylquinolin-4-ol + trans,trans-Farnesyl diphosphate <=> Aurachin D + Diphosphate
Aurachin D + NADPH + H+ + Oxygen <=> Aurachin C + NADP+ + H2O
Aurachin B + NADPH + H+ + Oxygen <=> Aurachin B epoxide + NADP+ + H2O
Aurachin B + NADH + H+ + Oxygen <=> Aurachin B epoxide + NAD+ + H2O
Aurachin B epoxide <=> Aurachin A
L-Methionine + Indolepyruvate <=> 4-Methylthio-2-oxobutanoic acid + L-Tryptophan
ATP + L-Proline <=> Diphosphate + (L-Prolyl)adenylate
(L-Prolyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Prolyl-[pcp]
ent-Isokaurene + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ATP + Pyridinium-3,5-biscarboxylic acid mononucleotide <=> Diphosphate + 5-Carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate
5-Carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate + [Protein]-L-cysteine <=> AMP + [Protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine
[Protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [Protein]-dehydroalanine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide
[Protein]-L-cysteine + Pyridinium-3,5-biscarboxylic acid mononucleotide + ATP <=> [Protein]-dehydroalanine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide + AMP + Diphosphate
ATP + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide <=> Diphosphate + 1-(5-O-Phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate
1-(5-O-Phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate + [Protein]-L-cysteine <=> AMP + [Protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine
[Protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [Protein]-dehydroalanine + Pyridinium-3,5-bisthiocarboxylate mononucleotide
[Protein]-L-cysteine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide + ATP <=> [Protein]-dehydroalanine + Pyridinium-3,5-biscarboxylic acid mononucleotide + AMP + Diphosphate
6-Methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + Reduced acceptor + Oxygen <=> 3-Demethylubiquinol + Acceptor + H2O
Albendazole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Albendazole S-oxide + [Oxidized NADPH---hemoprotein reductase] + H2O
Fenbendazole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Fenbendazole S-oxide + [Oxidized NADPH---hemoprotein reductase] + H2O
Albendazole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Hydroxyalbendazole + [Oxidized NADPH---hemoprotein reductase] + H2O
Fenbendazole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4'-Hydroxyfenbendazole + [Oxidized NADPH---hemoprotein reductase] + H2O
Long-chain fatty acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> omega-Hydroxy-long-chain fatty acid + [Oxidized NADPH---hemoprotein reductase] + H2O
beta-Dihydromenaquinone-9 + 2 Reduced ferredoxin + Oxygen <=> omega-Hydroxy-beta-dihydromenaquinone-9 + 2 Oxidized ferredoxin + H2O
Dihydrorhizobitoxine + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Rhizobitoxine + 2 Oxidized ferredoxin + 2 H2O
UDP-N-acetyl-D-glucosamine + Decaprenol phosphate <=> UMP + GlcNAc-pyrophosphoryldecaprenol
(2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 4-[(E)-2-Isocyanoethenyl]phenol + Succinate + 2 CO2 + H2O
dTDP-L-rhamnose + GlcNAc-pyrophosphoryldecaprenol <=> dTDP + Rhamnosyl-N-acetyl-glucosaminyl-decaprenyl diphosphate
UDP-alpha-D-galactofuranose + Rhamnosyl-N-acetyl-glucosaminyl-decaprenyl diphosphate <=> UDP + Glycolipid 3
UDP-alpha-D-galactofuranose + Glycolipid 3 <=> UDP + Glycolipid 4
UDP-alpha-D-galactofuranose + Glycolipid 4 <=> UDP + Glycolipid 5
(2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> (2E)-3-(4-Hydroxyphenyl)-2-isocyanoprop-2-enoate + Succinate + CO2 + H2O
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 3-[(Z)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 3-[(E)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O
12 Reduced ferredoxin + 12 H+ + Nitrogen + 40 ATP + 40 H2O <=> 12 Oxidized ferredoxin + 3 Hydrogen + 2 Ammonia + 40 ADP + 40 Orthophosphate
Acetyl-CoA + L-Glutamate 5-semialdehyde <=> CoA + N-Acetyl-L-glutamate 5-semialdehyde
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] <=> Ornithine lipid + Acyl-carrier protein
2 2-Acetylphloroglucinol <=> 2,4-Diacetylphloroglucinol + Phloroglucinol
UDP-glucose + Phloretin <=> UDP + Phlorizin
Geranyl diphosphate + 3-[(Z)-2-Isocyanoethenyl]-1H-indole <=> 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + Diphosphate
Dihydrochanoclavine-I aldehyde + NADP+ <=> Chanoclavine-I aldehyde + NADPH + H+
Dihydrochanoclavine-I aldehyde + H+ <=> 6,8-Dimethyl-6,7-didehydroergoline + H2O
O-Phospho-L-serine + Thiosulfate <=> S-Sulfo-L-cysteine + Orthophosphate
Festuclavine <=> Fumigaclavine B
Chanoclavine-I aldehyde + H+ <=> 6,8-Dimethyl-6,7,8,9-tetradehydroergoline + H2O
2-O-(alpha-D-Mannosyl)-D-glycerate + H2O <=> D-Mannose + D-Glycerate
[SoxY protein]-S-sulfosulfanyl-L-cysteine + H2O <=> [SoxY protein]-S-sulfanyl-L-cysteine + Sulfate
[SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + H2O <=> [SoxY protein]-S-disulfanyl-L-cysteine + Sulfate
S-Adenosyl-L-methionine + H2O <=> Adenosine + L-Methionine
ATP + [SAMP]-Gly-Gly <=> Diphosphate + [SAMP]-Gly-Gly-AMP
UDP-glucuronate + Dolichyl beta-D-glucosyl phosphate <=> UDP + Dolichyl beta-D-glucuronosyl-(1->3)-beta-D-glucosyl phosphate
Cannabigerolate + Oxygen <=> Delta9-Tetrahydrocannabinolate + Hydrogen peroxide
Delta9-Tetrahydrocannabinolate <=> Dronabinol + CO2
Cannabidiolic acid <=> Cannabidiol + CO2
4-Dimethylallyl-L-abrine <=> Chanoclavine-I
3-Oxocholan-24-oyl-CoA + NAD+ <=> 3-Oxochol-4-en-24-oyl-CoA + NADH + H+
3-Oxochol-4-en-24-oyl-CoA + NAD+ <=> 3-Oxochola-4,6-dien-24-oyl-CoA + NADH + H+
12alpha-Hydroxy-3-oxocholan-24-oyl-CoA + NAD+ <=> 12alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
12alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+ <=> 12alpha-Hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + NADH + H+
7alpha,12alpha-Dihydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7alpha,12alpha-Dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
7alpha-Hydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
7beta-Hydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7beta-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
Dihydro-4-coumaroyl-CoA + NADP+ <=> p-Coumaroyl-CoA + NADPH + H+
Dihydroferuloyl-CoA + NADP+ <=> Feruloyl-CoA + NADPH + H+
8-Amino-8-demethylriboflavin 5'-phosphate + H2O <=> 8-Amino-8-demethylriboflavin + Orthophosphate
Carotenoid beta-end group + 2 Acceptor <=> Carotenoid phi-end group + 2 Reduced acceptor
Carotenoid beta-end group + 2 Acceptor <=> Carotenoid chi-end group + 2 Reduced acceptor
Dihydro-4-coumaroyl-CoA + 3 Malonyl-CoA <=> Phloretin + 4 CoA + 3 CO2
14alpha-Methylsteroid + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Delta14-Steroid + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
14alpha-Methylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 14alpha-Hydroxymethylsteroid + [Oxidized NADPH---hemoprotein reductase] + H2O
14alpha-Hydroxymethylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 14alpha-Formylsteroid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
14alpha-Formylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Delta14-Steroid + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O
Abietinol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Abietate + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Abietal + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abietate + [Oxidized NADPH---hemoprotein reductase] + H2O
1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3-phosphate + Orthophosphate
1-O-(2-Acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + H2O <=> 1-O-[2-(Acetylamino)-2-deoxy-alpha-D-glucopyranosyl]-D-myo-Inositol + Orthophosphate
Coniferyl alcohol <=> (+)-Pinoresinol
Deoxypodophyllotoxin <=> Podophyllotoxin
(+)-Germacrene A + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Germacrene A acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Germacra-1(10),4,11(13)-trien-12-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Germacra-1(10),4,11(13)-trien-12-al + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Germacra-1(10),4,11(13)-trien-12-al + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Germacrene A acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Oxidized NADPH---hemoprotein reductase] + H2O
6alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Costunolide + H2O
4-Cresol + 2 Oxidized azurin + H2O <=> p-Hydroxybenzyl alcohol + 2 Reduced azurin + 2 H+
p-Hydroxybenzyl alcohol + 2 Oxidized azurin <=> 4-Hydroxybenzaldehyde + 2 Reduced azurin + 2 H+
Crocetin dialdehyde <=> Crocetin
(3S)-3-Hydroxycyclocitral <=> Picrocrocin
Picrocrocin <=> Safranal
17-O-Acetylnorajmaline + S-Adenosyl-L-methionine <=> 17-O-Acetylajmaline + S-Adenosyl-L-homocysteine
(9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid + H2O <=> 9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid
9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid + NADPH + H+ <=> 9-Hydroxy-12-oxo-15(Z)-octadecenoic acid + NADP+
Psilocybin <=> Psilocin
L-Galactono-1,4-lactone + 4 Ferricytochrome c <=> Dehydroascorbate + 4 Ferrocytochrome c + 4 H+
Coniferyl alcohol <=> (-)-Pinoresinol
L-Galactonate + NAD+ <=> D-Tagaturonate + NADH + H+
5-Aminosalicylate + Oxygen <=> (2Z,4E)-4-Amino-6-oxohepta-2,4-dienedioate
ATP + Medium-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Medium-chain acyl-[acyl-carrier protein]
(-)-Bornane-2,5-dione + Reduced FMN + Oxygen <=> (-)-5-Oxo-1,2-campholide + FMN + H2O
L-Tyrosine + D-Ribulose 5-phosphate <=> (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O
L-Tryptophan + D-Ribulose 5-phosphate <=> (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O
N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + Ammonia <=> 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + H2O
(+)-Pinoresinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (+)-Piperitol + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
(+)-Piperitol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Sesamin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
L-Galactono-1,5-lactone + H2O <=> L-Galactonate
L-Galactose + NADP+ <=> L-Galactono-1,5-lactone + NADPH + H+
S-Adenosyl-L-methionine + 1,6-Didemethyltoxoflavin <=> S-Adenosyl-L-homocysteine + Reumycin
S-Adenosyl-L-methionine + Reumycin <=> S-Adenosyl-L-homocysteine + Toxoflavine
Octanoyl-CoA + 2-O-[alpha-D-Glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate <=> CoA + 2-O-[6-O-Octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate
UDP-glucose + 2-Acylphloroglucinol <=> UDP + 2-Acylphloroglucinol 1-O-beta-D-glucoside
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine <=> 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine <=> 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine
[SoxY protein]-L-cysteine + Thiosulfate + 2 Ferricytochrome c <=> [SoxY protein]-S-sulfosulfanyl-L-cysteine + 2 Ferrocytochrome c + 2 H+
[SoxY protein]-S-sulfanyl-L-cysteine + Thiosulfate + 2 Ferricytochrome c <=> [SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + 2 Ferrocytochrome c + 2 H+
Hapalindole U + 2-Oxoglutarate + Oxygen + Cl- <=> Hapalindole G + Succinate + CO2 + H2O
12-epi-Fischerindole U + 2-Oxoglutarate + Oxygen + Cl- <=> 12-epi-Fischerindole G + Succinate + CO2 + H2O
Oleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z)-Octadecadienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Icosenoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (8Z,11Z)-Icosadienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
(8Z,11Z)-Icosadienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (5Z,8Z,11Z)-Icosatrienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
(11Z,14Z,17Z)-Icosatrienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (8Z,11Z,14Z,17Z)-Icosatetraenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
(11Z,14Z)-Icosadienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 8,11,14-Eicosatrienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Palmitoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Sapienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Palmitoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Palmitoleoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
L-Threonyl-[L-threonyl-carrier protein] + 2-Oxoglutarate + Oxygen + Cl- <=> 4-Chloro-L-threonyl-[L-threonyl-carrier protein] + Succinate + CO2 + H2O
Cyclooctat-9-en-7-ol + Reduced acceptor + Oxygen <=> Cyclooctat-9-ene-5,7-diol + Acceptor + H2O
Cyclooctat-9-ene-5,7-diol + Reduced acceptor + Oxygen <=> Cyclooctatin + Acceptor + H2O
beta-Carotene <=> Echinenone
Echinenone <=> Canthaxanthin
cis-trans-Nepetalactol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Iridotrial + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Iridotrial + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Deoxyloganetate + [Oxidized NADPH---hemoprotein reductase] + H2O
2 ATP + 2 Cob(II)alamin + [Reduced NADPH---hemoprotein reductase] <=> 2 Triphosphate + 2 Cobamide coenzyme + [Oxidized NADPH---hemoprotein reductase]
2 ATP + 2 Cob(II)yrinate a,c diamide + [Reduced NADPH---hemoprotein reductase] <=> 2 Triphosphate + 2 Adenosyl cobyrinate a,c diamide + [Oxidized NADPH---hemoprotein reductase]
Ammonia + HCO3- <=> Carbamate + H2O
Palmitoylphosphatidylcholine + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate <=> 2-Acyl-sn-glycero-3-phosphocholine + Lipid IVB
L-Cysteine-S-conjugate + H2O <=> Thiol + Ammonia + Pyruvate
Octadecanoyl-[acyl-carrier protein] + H. pylori KDO2-lipid IVA <=> Stearoyl-KDO2-lipid IVA + Acyl-carrier protein
Tetradecanoyl-[acp] + Stearoyl-KDO2-lipid IVA <=> H. pylori KDO2-lipid A + Acyl-carrier protein
KDO2-lipid A + H2O <=> 3'-O-Deacylated KDO2-lipid A + (R)-3-(Tetradecanoyloxy)tetradecanoic acid
Tetradecanoyl-[acp] + (9Z)-Hexadec-9-enoyl-KDO2-lipid IV(A) <=> Palmitoleoyl-myristoyl-KDO2-lipid A + Acyl-carrier protein
Lipid IVB + H2O <=> Deacyl-lipid IVB + (R)-3-Hydroxymyristic acid
2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate + H2O <=> Deacyl-lipid IVA + (R)-3-Hydroxymyristic acid
Palmitoylphosphatidylcholine + Deacyl-lipid IVA <=> 2-Acyl-sn-glycero-3-phosphocholine + Deacyl-lipid IVB
H. pylori KDO2-lipid A + H2O <=> 1-Dephospho-KDO2-lipid A + Orthophosphate
Phosphatidylethanolamine + 1-Dephospho-KDO2-lipid A <=> Diacylglycerol + 1-PEtN-KDO2-lipid A
1-PEtN-KDO-lipid A + H2O <=> 4'-Dephosphorylated 1-PEtN-KDO-lipid A + Orthophosphate
4'-Dephosphorylated 1-PEtN-KDO-lipid A + H2O <=> H. pylori KDO-lipid A + (R)-3-(Tetradecanoyloxy)hexadecanoic acid
Linoleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (9Z,12Z,15Z)-Octadecatrienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Palmitoylphosphatidylcholine + Lipid IIA <=> 2-Acyl-sn-glycero-3-phosphocholine + Lipid IIB
Undecaprenyl phosphate alpha-L-Ara4N + Lipid IVB <=> Lipid IIB + di-trans,poly-cis-Undecaprenyl phosphate
DIMBOA-glucoside + H2O <=> DIMBOA + D-Glucose
DIBOA-glucoside + H2O <=> DIBOA + D-Glucose
KDO2-lipid A + 2-Oxoglutarate + Oxygen <=> (S)-2-Hydroxymyristate-modified lipid A + Succinate + CO2
Palmitoylphosphatidylcholine + KDO2-lipid A <=> 2-Acyl-sn-glycero-3-phosphocholine + C16-KDO2-lipid A
Oxaloacetate + 2 Sodium cation <=> Pyruvate + CO2 + 2 Sodium cation
Naringenin + S-Adenosyl-L-methionine <=> Isosakuranetin + S-Adenosyl-L-homocysteine
Cadaverine + 2-Oxoglutarate <=> 5-Aminopentanal + L-Glutamate
5-Aminopentanal + NAD+ + H2O <=> 5-Aminopentanoate + NADH + H+
Glutarate + 2-Oxoglutarate + Oxygen <=> (S)-2-Hydroxyglutarate + Succinate + CO2
(S)-2-Hydroxyglutarate + Quinone <=> 2-Oxoglutarate + Hydroquinone
Flavanone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2-Hydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O
1-PEtN-KDO2-lipid A + H2O <=> 1-PEtN-KDO-lipid A + 3-Deoxy-D-manno-octulosonate
D-Glucosamine 6-phosphate <=> D-Galactosamine 6-phosphate
D-Galactosamine 6-phosphate <=> alpha-D-Galactosamine 1-phosphate
Scopoletin + 2-Oxoglutarate + Oxygen <=> Fraxetin + Succinate + CO2
Fraxetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Sideretin + [Oxidized NADPH---hemoprotein reductase] + H2O
Dolabradiene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 15,16-Epoxydolabrene + H2O + [Oxidized NADPH---hemoprotein reductase]
15,16-Epoxydolabrene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 3beta-Hydroxy-15,16-epoxydolabrene + H2O + [Oxidized NADPH---hemoprotein reductase]
(S)-beta-Macrocarpene + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Zealexin A1 + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase]
(S)-beta-Macrocarpene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> [(4S)-4-(5,5-Dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + H2O + [Oxidized NADPH---hemoprotein reductase]
[(4S)-4-(5,5-Dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (4S)-4-(5,5-Dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + 2 H2O + [Oxidized NADPH---hemoprotein reductase]
(4S)-4-(5,5-Dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Zealexin A1 + H2O + [Oxidized NADPH---hemoprotein reductase]
cis-trans-Nepetalactol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 7-Deoxyloganetate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
cis-trans-Nepetalactol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Deoxyloganetic alcohol + [Oxidized NADPH---hemoprotein reductase] + H2O
Indole-3-carbonyl nitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Hydroxyindole-3-carbonyl nitrile + [Oxidized NADPH---hemoprotein reductase] + H2O
1-Hexacosanoyl-2-acyl-[phosphoglycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 1-[(17Z)-Hexacos-17-enoyl]-2-acyl-[phosphoglycerolipid] + 2 Ferricytochrome b5 + 2 H2O
1-Tetracosanoyl-2-acyl-[phosphoglycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 1-[(15Z)-Tetracos-15-enoyl]-2-acyl-[phosphoglycerolipid] + 2 Ferricytochrome b5 + 2 H2O
L-Tyrosinal + NADP+ + AMP + Diphosphate <=> L-Tyrosine + NADPH + H+ + ATP
Meromycolyl-[acyl-carrier protein] + NAD+ <=> trans-Delta2-Meromycolyl-[acyl-carrier protein] + NADH + H+
Staphylopine + NADP+ + H2O <=> (2S)-2-Amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + Pyruvate + NADPH + H+
2 S-Adenosyl-L-methionine + Menaquinone + Reduced flavodoxin <=> S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + 8-Methylmenaquinone + Oxidized flavodoxin
2 S-Adenosyl-L-methionine + 2-Demethylmenaquinone + Reduced flavodoxin <=> S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + 2-Demethyl-8-methylmenaquinone + Oxidized flavodoxin
Acyl-[acyl-carrier protein] + Orthophosphate <=> Acyl phosphate + Acyl-carrier protein
Acyl phosphate + sn-Glycerol 3-phosphate <=> 1-Acyl-sn-glycerol 3-phosphate + Orthophosphate
Acetyl-CoA + alpha-D-Galactosamine 1-phosphate <=> CoA + N-Acetyl-alpha-D-galactosamine 1-phosphate
2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate <=> D-Glucose 1-phosphate + Glycerol
UDP-D-xylose + G13094 <=> UDP + G13095
ATP + 5-Amino-1-(beta-D-ribosyl)imidazole <=> ADP + Aminoimidazole ribotide
ATP + Cytidine 5'-diphosphoramidate <=> ADP + Cytidine 3'-phospho-5'-diphosphoramidate
CTP + N5-Phospho-L-glutamine <=> Diphosphate + N5-(Cytidine 5'-diphosphoramidyl)-L-glutamine
D-Xylono-1,4-lactone 5-phosphate + H2O <=> 5-Phospho-D-xylonate
L-Arabino-1,4-lactone 5-phosphate + H2O <=> 5-Phospho-L-arabinate
2-O-(alpha-D-Glucopyranosyl)-D-glycerate + H2O <=> D-Glucose + D-Glycerate
N5-(Cytidine 5'-diphosphoramidyl)-L-glutamine + H2O <=> Cytidine 5'-diphosphoramidate + L-Glutamate
(R)-3-(3,4-Dihydroxyphenyl)lactate + NADP+ <=> 3-(3,4-Dihydroxyphenyl)pyruvate + NADPH + H+
7-Deoxyloganetic alcohol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Iridotrial + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
1,4-Dihydroxy-2-naphthoate <=> 2-Carboxy-1,4-naphthoquinone
Phytyl diphosphate + 2-Carboxy-1,4-naphthoquinone <=> 2-Phytyl-1,4-naphthoquinone + Diphosphate + CO2
(R)-(Indol-3-yl)lactate + NAD+ <=> Indolepyruvate + NADH + H+
cis-3-Alkyl-4-alkyloxetan-2-one <=> Alkene + CO2
ent-Copalyl diphosphate <=> Dolabradiene + Diphosphate
trans,trans-Farnesyl diphosphate + 2 H2O <=> 7-epi-ent-Eudesmane-5,11-diol + Diphosphate
trans,trans-Farnesyl diphosphate <=> alpha-Selinene + Diphosphate
trans,trans-Farnesyl diphosphate <=> (-)-5-Epieremophilene + Diphosphate
Narcotoline + S-Adenosyl-L-methionine <=> alpha-Narcotine + S-Adenosyl-L-homocysteine
S-Adenosyl-L-methionine + Nocamycin E <=> S-Adenosyl-L-homocysteine + Nocamycin I
S-Adenosyl-L-methionine + Xanthohumol <=> S-Adenosyl-L-homocysteine + 4-O-Methylxanthohumol
Isopyridoxal + NAD+ + H2O <=> 3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADH + H+
Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 8beta-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Oxidized NADPH---hemoprotein reductase] + H2O
8beta-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6alpha,8beta-Dihydroxygermacra-1(10),4,11(13)-trien-12-oate + [Oxidized NADPH---hemoprotein reductase] + H2O
6alpha,8beta-Dihydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Eupatolide + H2O
Geranylgeranyl diphosphate <=> beta-Pinacene + Diphosphate
8beta-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eupatolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate + H2O <=> AMP + Diphosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
ATP + UDP-N-acetylmuramoyl-L-alanine + L-Glutamate <=> ADP + Orthophosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate
Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 8alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Oxidized NADPH---hemoprotein reductase] + H2O
8alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate <=> 8-epi-Inunolide + H2O
Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 8-epi-Inunolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Flavanone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Flavone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Liquiritigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7,4'-Dihydroxyflavone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Naringenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Apigenin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Eriodictyol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Luteolin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Prephytoene diphosphate + NADPH + H+ <=> Lycopaoctaene + Diphosphate + NADP+
2 Geranylgeranyl diphosphate + NADPH + H+ <=> Lycopaoctaene + 2 Diphosphate + NADP+
Tetrahydroalstonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Alstonine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O + 2 H+
Dimethylallyl diphosphate + Lycopene + Acceptor + H2O <=> Nonaflavuxanthin + Reduced acceptor + Diphosphate
Dimethylallyl diphosphate + Nonaflavuxanthin + Acceptor + H2O <=> Flavuxanthin + Reduced acceptor + Diphosphate
Dimethylallyl diphosphate + Lycopene + H2O <=> Dihydroisopentenyldehydrorhodopin + Diphosphate
Dimethylallyl diphosphate + Isopentenyldehydrorhodopin + H2O <=> Dihydrobisanhydrobacterioruberin + Diphosphate
Long-chain acyl-CoA + alpha,alpha-Trehalose <=> 2-(Long-chain-fatty acyl)-trehalose + CoA
Mycolipenoyl-CoA + 2-(Long-chain-fatty acyl)-trehalose <=> 2-(Long-chain-fatty acyl)-3-mycolipenoyl-trehalose + CoA
Medium-chain 3-oxoacyl-[acyl-carrier protein] + Glycerone phosphate <=> 2-Oxo-3-(phosphooxy)propyl 3-oxoalkanoate + Acyl-carrier protein
UDP-glucose + 2'-Hydroxy-beta-oxodihydrochalcone <=> UDP + 3'-(beta-D-Glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone
5-Methyl-H4SPT + Coenzyme M + 2 Sodium cation(side 1) <=> Tetrahydrosarcinapterin + 2-(Methylthio)ethanesulfonate + 2 Sodium cation(side 2)
G13087 + UDP-N-acetyl-D-galactosamine <=> O-mannose core M3 + UDP
O-mannose core M3 + ATP <=> Phospho-core M3 + ADP
Phospho-core M3 + CDP-ribitol <=> G13093 + CMP
G13093 + CDP-ribitol <=> G13094 + CMP
G13095 + UDP-D-glucuronate <=> G13096 + UDP
G13096 + UDP-D-xylose <=> G13097 + UDP
G13097 + UDP-D-glucuronate <=> G13098 + UDP
Dolichol + NADP+ <=> Polyprenol + NADPH + H+
ATP + Malonate + CoA <=> AMP + Diphosphate + Malonyl-CoA
o-Methoxyphenol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Catechol + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O
Isoeugenol + Oxygen <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetaldehyde
Indole-3-acetate <=> Skatole + CO2
D-Ornithine <=> Putrescine + CO2
D-Lysine <=> Cadaverine + CO2
p-Coumaroyl-CoA + 2-Oxoglutarate + Oxygen <=> 2,4-Dihydroxycinnamoyl-CoA + Succinate + CO2
(4R)-4,2'-Dihydroxyisoflavan <=> Pterocarpan + H2O
ATP + L-2,3-Diaminopropanoate + Citrate <=> AMP + Diphosphate + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate
2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate <=> 2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO2
2,4-Dihydroxycinnamoyl-CoA <=> Umbelliferone + CoA
ATP + 2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + L-2,3-Diaminopropanoate <=> AMP + Diphosphate + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate
ATP + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-Oxoglutarate <=> AMP + Diphosphate + Staphyloferrin B
L-Histidine <=> D-Histidine
6-Sulfo-alpha-D-quinovose <=> 6-Sulfo-beta-D-quinovose
Protein lysine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3S)-3-hydroxy-L-lysine + Succinate + CO2
G10558 + UDP-N-acetyl-D-glucosamine <=> G13127 + UDP
14alpha-Methylsteroid + 6 Reduced ferredoxin + 6 H+ + 3 Oxygen <=> Delta14-Steroid + Formate + 6 Oxidized ferredoxin + 4 H2O
14alpha-Methylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 14alpha-Hydroxymethylsteroid + 2 Oxidized ferredoxin + H2O
Dimethyl sulfide + NADH + H+ + Oxygen <=> Dimethyl sulfoxide + NAD+ + H2O
Dimethyl sulfoxide + NADH + H+ + Oxygen <=> Dimethyl sulfone + NAD+ + H2O
14alpha-Hydroxymethylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 14alpha-Formylsteroid + 2 Oxidized ferredoxin + 2 H2O
14alpha-Formylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Delta14-Steroid + Formate + 2 Oxidized ferredoxin + H2O
Lanosterol + 6 Reduced ferredoxin + 6 H+ + 3 Oxygen <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Formate + 6 Oxidized ferredoxin + 4 H2O
Luteothin + 4 Reduced ferredoxin + 2 Oxygen + 4 H+ <=> Aureothin + 4 Oxidized ferredoxin + 3 H2O
Luteothin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> (7R)-7-Hydroxyluteothin + 2 Oxidized ferredoxin + H2O
(7R)-7-Hydroxyluteothin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Aureothin + 2 Oxidized ferredoxin + 2 H2O
Acetyl-CoA + n Malonyl-CoA + n NADPH + n NADH + 2n H+ <=> Long-chain acyl-CoA + n CoA + n CO2 + n NADP+ + n NAD+ + n H2O
Long-chain acyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Long-chain fatty acid
ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine <=> ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol
beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol + Ammonia <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine + Orthophosphate
Cyanuric acid + H2O <=> 1-Carboxybiuret
1-Carboxybiuret + H2O <=> Urea-1,3-dicarboxylate + Ammonia
Urea-1,3-dicarboxylate <=> Urea-1-carboxylate + CO2
1-Carboxybiuret <=> Biuret + CO2
S-Adenosyl-L-methionine + Demethylluteothin <=> S-Adenosyl-L-homocysteine + Luteothin
6 Malonyl-CoA + 5 NADPH + NADH + 6 H+ <=> (2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + 6 CoA + 5 NADP+ + NAD+ + 6 CO2 + 4 H2O
2 GDP-mannose + Bis(myo-inositol) 1,3'-phosphate <=> 2 GDP + 2-O-(beta-D-Mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate
GDP-mannose + Bis(myo-inositol) 1,3'-phosphate <=> GDP + 2-O-(beta-D-Mannosyl)-bis(myo-inositol) 1,3'-phosphate
GDP-mannose + 2-O-(beta-D-Mannosyl)-bis(myo-inositol) 1,3'-phosphate <=> GDP + 2-O-(beta-D-Mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate
S-Adenosyl-L-methionine + D-Histidine <=> (2S)-2-Amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + 5'-Methylthioadenosine
ADP + L-Serine <=> AMP + O-Phospho-L-serine
(2E,5S,6E,8E,10E)-1-Aminododeca-2,6,8,10-tetraen-5-ol + Pyruvate <=> (2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + L-Alanine
ATP + L-Serine <=> ADP + O-Phospho-L-serine
Cyclic di-3',5'-adenylate + H2O <=> 5'-O-Phosphonoadenylyl-(3'->5')-adenosine
5'-O-Phosphonoadenylyl-(3'->5')-adenosine + H2O <=> 2 AMP
3-O-Acetylpapaveroxine + H2O <=> Narcotine hemiacetal + Acetate
3 3'-(Hydroxy)phthioceranyl-2'-palmitoyl(stearoyl)-2-O-sulfo-alpha,alpha-trehalose <=> 3,6,6'-Tris-(hydroxy)phthioceranyl-2-palmitoyl(stearoyl)-2'-sulfo-alpha,alpha-trehalose + 2 2'-Palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose
Sucrose + Dextran <=> D-Fructose + (1->6)-alpha-D-Glucan containing a (1->3)-alpha-D-glucose branch
G00146 + Dolichyl phosphate D-mannose <=> G13128 + Dolichyl phosphate
G13128 + Phosphatidylethanolamine <=> G00148 + 1,2-Diacyl-sn-glycerol
N3-Fumaroyl-L-2,3-diaminopropanoate + L-Glutamine + ATP + H2O <=> 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Glutamate + ADP + Orthophosphate
D-Ornithine + Citrate + ATP <=> N5-Citryl-D-ornithine + AMP + Diphosphate
N5-Citryl-D-ornithine + Citrate + ATP <=> Staphyloferrin A + AMP + Diphosphate
Squalene + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (S)-2,3-Epoxysqualene + 2 Ferricytochrome b5 + H2O
Propanoyl-CoA + Oxygen <=> Propenoyl-CoA + Hydrogen peroxide
3beta-Hydroxy-4,4-dimethylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + NAD+ + H2O
3beta-Hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4beta-formyl-4alpha-methylsteroid + NAD+ + 2 H2O
3beta-Hydroxy-4beta-formyl-4alpha-methylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD+ + H2O
3beta-Hydroxy-4,4-dimethylsteroid + 3 NADH + 3 H+ + 3 Oxygen <=> 3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + 3 NAD+ + 4 H2O
3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD+ <=> 4alpha-Methyl-3-oxosteroid + NADH + CO2 + H+
3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP+ <=> 4alpha-Methyl-3-oxosteroid + NADPH + CO2 + H+
Geranylgeranyl diphosphate <=> Hydropyrene + Diphosphate
Geranylgeranyl diphosphate + H2O <=> Hydropyrenol + Diphosphate
Geranylgeranyl diphosphate <=> Isoelisabethatriene + Diphosphate
3beta-Hydroxysteroid-4alpha-carboxylate + NAD+ <=> 3-Oxosteroid + NADH + CO2 + H+
beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16alpha-Hydroxy-beta-amyrin + [Oxidized NADPH---hemoprotein reductase] + H2O
24-Methylidenecycloartanol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-(Hydroxymethyl)-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Ferricytochrome b5 + H2O
4alpha-(Hydroxymethyl)-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-Formyl-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Ferricytochrome b5 + 2 H2O
4alpha-Formyl-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + 2 Ferricytochrome b5 + H2O
3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + NAD+ <=> Cycloeucalenone + NADH + CO2 + H+
24-Methylenelophenol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-(Hydroxymethyl)ergosta-7,24(24(1))-dien-3beta-ol + 2 Ferricytochrome b5 + H2O
4alpha-(Hydroxymethyl)ergosta-7,24(24(1))-dien-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-Formylergosta-7,24(24(1))-dien-3beta-ol + 2 Ferricytochrome b5 + 2 H2O
4alpha-Formylergosta-7,24(24(1))-dien-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate + 2 Ferricytochrome b5 + H2O
3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate + NAD+ <=> Episterone + NADH + CO2 + H+
4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + NAD+ <=> Avenastenone + NADH + CO2 + H+
24-Methylidenecycloartanol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + 6 Ferricytochrome b5 + 4 H2O
24-Methylenelophenol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate + 6 Ferricytochrome b5 + 4 H2O
24-Ethylidenelophenol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 6 Ferricytochrome b5 + 4 H2O
8 (S)-Methylmalonyl-CoA + Palmitoyl-[(hydroxy)phthioceranic acid synthase] + 16 NADPH + 16 H+ <=> 8 CoA + C40-Phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 16 NADP+ + 8 CO2 + 8 H2O
7 (S)-Methylmalonyl-CoA + Palmitoyl-[(hydroxy)phthioceranic acid synthase] + 14 NADPH + 14 H+ <=> 7 CO2 + C37-Phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 14 NADP+ + 7 CoA + 7 H2O
UDP-glucose + Protopanaxadiol <=> UDP + Ginsenoside C-K
UDP-glucose + Protopanaxadiol <=> UDP + (20S)-Ginsenoside Rh2
UDP-glucose + Ginsenoside C-K <=> UDP + Ginsenoside F2
UDP-glucose + (20S)-Ginsenoside Rh2 <=> UDP + Ginsenoside Rg3
UDP-glucose + Ginsenoside F2 <=> UDP + Ginsenoside Rd
UDP-glucose + Ginsenoside F1 <=> UDP + Ginsenoside Rg1
UDP-glucose + Protopanaxatriol <=> UDP + Ginsenoside Rh1
UDP-glucose + Oleanolic acid <=> UDP + Oleanolate 3-O-beta-D-glucoside
3''-O-Acetyl-ADP-D-ribose + H2O <=> ADP-ribose + Acetate
O-Acetyl-ADP-ribose + H2O <=> ADP-ribose + Acetate
2,4-Diacetylphloroglucinol + H2O <=> 2-Acetylphloroglucinol + Acetate
ATP + Octadecanoic acid <=> Diphosphate + (Stearoyl)adenylate
(Stearoyl)adenylate + Peptidyl-carrier protein <=> AMP + Stearoyl-[(hydroxy)phthioceranic acid synthase]
ATP + Octadecanoic acid + Peptidyl-carrier protein <=> AMP + Diphosphate + Stearoyl-[(hydroxy)phthioceranic acid synthase]
ATP + Hexadecanoic acid <=> Diphosphate + (Palmitoyl)adenylate
(Palmitoyl)adenylate + Peptidyl-carrier protein <=> AMP + Palmitoyl-[(hydroxy)phthioceranic acid synthase]
ATP + Hexadecanoic acid + Peptidyl-carrier protein <=> AMP + Diphosphate + Palmitoyl-[(hydroxy)phthioceranic acid synthase]
Cycloeucalenone + NADPH + H+ <=> Cycloeucalenol + NADP+
Episterone + NADPH + H+ <=> Episterol + NADP+
Avenastenone + NADPH + H+ <=> Delta7-Avenasterol + NADP+
3beta-Hydroxysteroid + NADP+ <=> 3-Oxosteroid + NADPH + H+
4alpha-Methylzymosterol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol + 6 Ferricytochrome b5 + 4 H2O
4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> Zymosterone + NADPH + H+ + CO2
Zymosterone + NADPH + H+ <=> Zymosterol + NADP+
3beta-Hydroxysteroid-4alpha-carboxylate + NADP+ <=> 3-Oxosteroid + CO2 + NADPH + H+
L-Lysine + 2-Oxoglutarate + Oxygen + Cl- + H+ <=> 4-Chloro-L-lysine + Succinate + CO2 + H2O
4-Chloro-L-lysine + Reduced acceptor + Oxygen <=> 2-Amino-4-chloro-4-pentenoic acid + Acceptor + Formaldehyde + Ammonia + H2O
2-Amino-4-chloro-4-pentenoic acid <=> L-Propargylglycine + Cl- + H+
L-Propargylglycine + L-Glutamate <=> gamma-L-Glutamyl-L-propargylglycine
gamma-L-Glutamyl-L-propargylglycine + 2-Oxoglutarate + Oxygen <=> L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + Succinate + CO2
L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + H2O <=> L-beta-Ethynylserine + L-Glutamate
L-Tryptophan + L-Phenylalanine <=> Cyclo(L-Trp-L-Phe)
Cyclo(L-Trp-L-Phe) + S-Adenosyl-L-methionine <=> N-Methyl-cyclo(L-Trp-L-Phe) + S-Adenosyl-L-homocysteine
2 N-Methyl-cyclo(L-Trp-L-Phe) <=> (-)-Ditryptophenaline
Linoleoyl-[glycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> alpha-Linolenoyl-[glycerolipid] + 2 Ferricytochrome b5 + 2 H2O
Anthranilate + L-Tryptophan + L-Alanine + 3 ATP <=> Fumiquinazoline F + 3 AMP + 3 Diphosphate + H2O
Fumiquinazoline F + 3 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Fumiquinazoline F-indoline-2',3'-diol + 3 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Fumiquinazoline F-indoline-2',3'-diol + L-Alanine + ATP <=> Fumiquinazoline A + AMP + Diphosphate + H2O
Fumiquinazoline A + Oxygen <=> Fumiquinazoline C + Hydrogen peroxide
Fumiquinazoline C <=> Fumiquinazoline D
2 Reduced [2Fe-2S] ferredoxin + NADP+ + H+ <=> 2 Oxidized [2Fe-2S] ferredoxin + NADPH
[Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster + 2 S-Adenosyl-L-methionine + 2 Reduced [2Fe-2S] ferredoxin + 8 H+ <=> Enzyme N6-(dihydrolipoyl)lysine + [Fe-S] cluster scaffold protein + 2 Hydrogen sulfide + 4 Fe2+ + 2 L-Methionine + 2 5'-Deoxyadenosine + 2 Oxidized [2Fe-2S] ferredoxin
[Glycine cleavage system H]-N6-octanoyl-L-lysine + [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster + 2 S-Adenosyl-L-methionine + 2 Reduced [2Fe-2S] ferredoxin + 8 H+ <=> Dihydrolipoylprotein + [Fe-S] cluster scaffold protein + 2 Hydrogen sulfide + 4 Fe2+ + 2 L-Methionine + 2 5'-Deoxyadenosine + 2 Oxidized [2Fe-2S] ferredoxin
[Glycine cleavage system H]-N6-octanoyl-L-lysine + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine
Lipoylprotein + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + Enzyme N6-(lipoyl)lysine
Octanoyl-[acp] + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + Acyl-carrier protein
Octanoyl-[acp] + Glycine cleavage system H <=> [Glycine cleavage system H]-N6-octanoyl-L-lysine + Acyl-carrier protein
ATP + Octanoic acid + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + AMP + Diphosphate
Octanoyl-[acp] + CoA <=> Octanoyl-CoA + Acyl-carrier protein
Octanoyl-CoA + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + CoA
Dihydrolipoylprotein + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + Enzyme N6-(dihydrolipoyl)lysine
ATP + (R)-Lipoate + Glycine cleavage system H <=> Lipoylprotein + AMP + Diphosphate
ATP + Dihydrolipoate <=> Dihydrolipoyl-AMP + Diphosphate
Dihydrolipoyl-AMP + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP + 2 H+
L-Tryptophan + L-Histidine <=> Histidyltryptophyldiketopiperazine
Histidyltryptophyldiketopiperazine + Dimethylallyl diphosphate <=> Roquefortine D + Diphosphate
Histidyltryptophyldiketopiperazine <=> Dehydrohistidyltryptophyldiketopiperazine
Dehydrohistidyltryptophyldiketopiperazine + Dimethylallyl diphosphate <=> Roquefortine C + Diphosphate
Roquefortine D <=> Roquefortine C
Roquefortine C + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Glandicoline A + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Glandicoline A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glandicoline B + [Oxidized NADPH---hemoprotein reductase] + H2O
Glandicoline B + S-Adenosyl-L-methionine <=> Meleagrin + S-Adenosyl-L-homocysteine
Roquefortine C + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N1-Hydroxy-roquefortine C + [Oxidized NADPH---hemoprotein reductase] + H2O
N1-Hydroxy-roquefortine C + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Roquefortine L + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Roquefortine L + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glandicoline B + [Oxidized NADPH---hemoprotein reductase] + H2O
N1-Hydroxy-roquefortine C + S-Adenosyl-L-methionine <=> Roquefortine F + S-Adenosyl-L-homocysteine
Roquefortine F + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Neoxaline + [Oxidized NADPH---hemoprotein reductase] + H2O
ATP + (R)-Lipoate + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP + Diphosphate
Lipoyl-AMP + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP
Hydroxymethylphosphonate + Oxygen <=> Formate + Orthophosphate
Methylphosphonate + 2-Oxoglutarate + Oxygen <=> Hydroxymethylphosphonate + Succinate + CO2
Cyclohexane-1-carboxyl-CoA + NADP+ <=> Cyclohex-1-ene-1-carboxyl-CoA + NADPH + H+
Fe-coproporphyrin III + Hydrogen peroxide <=> Harderoheme III + CO2 + 2 H2O
Harderoheme III + Hydrogen peroxide <=> Heme + CO2 + 2 H2O
trans,trans-Farnesyl diphosphate + H2O <=> Valerianol + Diphosphate
2 Methanethiol + NAD+ <=> Dimethyl disulfide + NADH + H+
S-Adenosyl-L-methionine + Cycloartenol <=> S-Adenosyl-L-homocysteine + Cyclolaudenol
Protein N6,N6,N6-trimethyl-L-lysine + 2 2-Oxoglutarate + 2 Oxygen <=> Protein N6-methyl-L-lysine + 2 Succinate + 2 Formaldehyde + 2 CO2
Protein N6,N6,N6-trimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein N6,N6-dimethyl-L-lysine + Succinate + Formaldehyde + CO2
Protein N6,N6,N6-trimethyl-L-lysine + 3 2-Oxoglutarate + 3 Oxygen <=> Protein lysine + 3 Succinate + 3 Formaldehyde + 3 CO2
Protein N6,N6-dimethyl-L-lysine + 2 Acceptor + 2 H2O <=> Protein lysine + 2 Formaldehyde + 2 Reduced acceptor
Protein N6,N6-dimethyl-L-lysine + Acceptor + H2O <=> Protein N6-methyl-L-lysine + Formaldehyde + Reduced acceptor
Protein N6-methyl-L-lysine + Acceptor + H2O <=> Protein lysine + Formaldehyde + Reduced acceptor
Stearoyl-CoA + 2-Sulfotrehalose <=> 2-O-Sulfo-2'-stearoyl-alpha,alpha-trehalose + CoA
Palmitoyl-CoA + 2-Sulfotrehalose <=> 2-O-Sulfo-2'-palmitoyl-alpha,alpha-trehalose + CoA
4-Nitrobenzoyl-CoA + Malonyl-CoA + 4 (S)-Methylmalonyl-CoA + 4 NADPH + 4 H+ <=> Demethylluteothin + 5 CO2 + 6 CoA + 4 NADP+ + 3 H2O
4-Nitrobenzoyl-CoA + Malonyl-CoA + 6 (S)-Methylmalonyl-CoA + 6 NADPH + 6 H+ <=> Demethyldeoxyspectinabilin + 7 CO2 + 8 CoA + 6 NADP+ + 5 H2O
UDP-glucose + Enterochelin <=> UDP + Monoglucosyl-enterobactin
UDP-glucose + Monoglucosyl-enterobactin <=> UDP + Diglucosyl-enterobactin
UDP-glucose + Diglucosyl-enterobactin <=> UDP + Triglucosyl-enterobactin
GDP-mannose + Very-long-chain inositol phospho-(2'R)-2'-hydroxyphytoceramide <=> Very-long-chain mannosylinositol phospho-(2'R)-2'-hydroxyphytoceramide + GDP
Enterochelin + H2O <=> N-(2,3-Dihydroxybenzoyl)-L-serine trimer
Triglucosyl-enterobactin + H2O <=> Triglucosyl-(2,3-dihydroxybenzoylserine)3
Diglucosyl-enterobactin + H2O <=> Diglucosyl-(2,3-dihydroxybenzoylserine)3
Monoglucosyl-enterobactin + H2O <=> Monoglucosyl-(2,3-dihydroxybenzoylserine)3
G00374 + H2O <=> G00272 + D-Mannose
N-Acyl-L-glutamine + H2O <=> L-Glutamine + Carboxylate
G10694 + 3 H2O <=> G00012 + 3 D-Mannose
Bilirubin + Oxidised coenzyme F420-(gamma-Glu)n <=> Biliverdin + Reduced coenzyme F420-(gamma-Glu)n
UDP-D-glucuronate + T antigen <=> UDP + Glucuronylated core 1 glycans (linear)
(+)-cis,cis-Nepetalactol + NAD+ <=> (+)-cis,cis-Nepetalactone + NADH + H+
cis-trans-Nepetalactol + NAD+ <=> Nepetalactone cis-trans-form + NADH + H+
ATP + Isophthalate + CoA <=> AMP + Diphosphate + Isophthalyl-CoA
Isophthalyl-CoA <=> Benzoyl-CoA + CO2
(R)-Phenyllactyl-CoA <=> (E)-Cinnamoyl-CoA + H2O
(R)-3-(4-Hydroxyphenyl)lactoyl-CoA <=> p-Coumaroyl-CoA + H2O
(R)-3-(Indol-3-yl)lactoyl-CoA <=> 3-(Indol-3-yl)acryloyl-CoA + H2O
Pre-sodorifen diphosphate <=> Sodorifen + Diphosphate
4-Amino-4-deoxychorismate <=> 4-Amino-4-deoxyprephenate
p-Coumaroyl-CoA + (R)-3-(4-Hydroxyphenyl)lactate <=> 4-Coumarate + (R)-3-(4-Hydroxyphenyl)lactoyl-CoA
3-(Indol-3-yl)acryloyl-CoA + (R)-(Indol-3-yl)lactate <=> 3-Indoleacrylate + (R)-3-(Indol-3-yl)lactoyl-CoA
ATP + Marinolic acid <=> AMP + Diphosphate + Marinoloyl-CoA
ATP + Pseudomonic acid <=> AMP + Diphosphate + Pseudomonoyl-CoA
Long-chain acyl-CoA + Sterol <=> CoA + Long-chain 3-hydroxysterol ester
2 S-Adenosyl-L-methionine + Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Reduced acceptor <=> S-Adenosyl-L-homocysteine + 5'-Deoxyadenosine + L-Methionine + Cytidine 5'-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + Acceptor
2-Hydroxyethylphosphonate + CTP <=> Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Diphosphate
Cytidine 5'-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + H2O <=> (S)-2-Hydroxypropylphosphonate + CMP
tRNA queuine + Acceptor + H2O <=> Epoxyqueuosine in tRNA + Reduced acceptor
Indole-3-acetate + 2-Oxoglutarate + Oxygen <=> 2-Oxoindole-3-acetate + Succinate + CO2
D-Apiofuranose + NAD+ <=> D-Apionolactone + NADH + H+
D-Apionate + NAD+ <=> 3-Oxoisoapionate + NADH + H+
Phenylacetic acid <=> Toluene + CO2
Hydrogen sulfide + L-Aspartate 4-semialdehyde + 2 Reduced ferredoxin + 2 H+ <=> L-Homocysteine + H2O + 2 Oxidized ferredoxin
L-Arginine + L-Lysine <=> L-Ornithine + Homoarginine
L-Glutamine + 4-Methylthio-2-oxobutanoic acid <=> 2-Oxoglutaramate + L-Methionine
2 Oxygen + Ubiquinol <=> 2 Superoxide + Ubiquinone + 2 H+
7-Deoxycylindrospermopsin + 2-Oxoglutarate + Oxygen <=> Cylindrospermopsin + Succinate + CO2
7-Deoxycylindrospermopsin + 2-Oxoglutarate + Oxygen <=> 7-epi-Cylindrospermopsin + Succinate + CO2
Stachydrine + NADH + H+ + Oxygen <=> N-Methyl-L-proline + Formaldehyde + NAD+ + H2O
Stachydrine + NADPH + H+ + Oxygen <=> N-Methyl-L-proline + Formaldehyde + NADP+ + H2O
(Indol-3-yl)acetyl-L-aspartate + H2O <=> Indole-3-acetate + L-Aspartate
R-S-Cysteinylglycine + H2O <=> L-Cysteine-S-conjugate + Glycine
Ethyl acetate + H2O <=> Acetate + Ethanol
Isoamyl acetate + H2O <=> 3-Methylbutanol + Acetate
(6E)-8-Oxogeranial + NADH + H+ <=> (S)-8-Oxocitronellyl enol + NAD+
(6E)-8-Oxogeranial + NADPH + H+ <=> (S)-8-Oxocitronellyl enol + NADP+
(S)-8-Oxocitronellyl enol <=> cis-trans-Nepetalactol
(S)-8-Oxocitronellyl enol <=> (+)-cis,cis-Nepetalactol
(+)-(1S,2S)-Pseudoephedrine + NAD+ <=> (S)-2-(Methylamino)-1-phenylpropan-1-one + NADH + H+
4-Amino-4-deoxyprephenate + NAD+ <=> 3-(4-Aminophenyl)pyruvate + NADH + CO2 + H+
S-Adenosyl-L-methionine + trans,trans-Farnesyl diphosphate <=> S-Adenosyl-L-homocysteine + Pre-sodorifen diphosphate
2 GDP-mannose + [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol <=> 2 GDP + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
2 GDP-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol <=> 2 GDP + [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
Sucrose + 1,3-alpha-D-Glucan(n) <=> D-Fructose + 1,3-alpha-D-Glucan(n+1)
Sucrose + Dextran <=> D-Fructose + (1->6)-alpha-D-Glucan containing a (1->2)-alpha-D-glucose branch
GDP-mannose + 1,2-beta-Oligomannan(n) <=> GDP + 1,2-beta-Oligomannan(n+1)
ATP + Amicoumacin A <=> ADP + Amicoumacin A 2-phosphate
Amicoumacin A 2-phosphate + H2O <=> Amicoumacin A + Orthophosphate
8-Oxo-GTP + H2O <=> 8-Oxo-GDP + Orthophosphate
8-Oxo-dGTP + H2O <=> 8-Oxo-dGDP + Orthophosphate
Phloretate + Electron-transferring flavoprotein <=> 4-Coumarate + Reduced electron-transferring flavoprotein
Phenylpropanoate + Electron-transferring flavoprotein <=> trans-Cinnamate + Reduced electron-transferring flavoprotein
3-(1H-Indol-3-yl)propanoate + Electron-transferring flavoprotein <=> 3-Indoleacrylate + Reduced electron-transferring flavoprotein
1-Acyl-sn-glycero-3-phosphoserine + H2O <=> Glycerophosphoserine + Fatty acid
Dibenzothiophene-5,5-dioxide + FMN-N5-peroxide <=> 2'-Hydroxybiphenyl-2-sulfinate + FMN-N5-oxide
FMN-N5-oxide + NADH <=> FMN + H2O + NAD+ + H+
L-Phenylalanine + Tetrahydropteridine + Oxygen <=> L-Tyrosine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
L-Tyrosine + Tetrahydropteridine + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
L-Tryptophan + Tetrahydropteridine + Oxygen <=> 5-Hydroxy-L-tryptophan + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
L-Phenylalanine + Tetrahydropteridine + Oxygen <=> 3-Hydroxy-L-phenylalanine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
Uracil + Reduced FMN + Oxygen + NADH <=> Ureidoacrylate + H2O + FMN + NAD+ + H+
Uracil + FMN-N5-peroxide <=> Ureidoacrylate + FMN-N5-oxide
Thymine + Reduced FMN + Oxygen + NADH <=> Methylureidoacrylate + H2O + FMN + NAD+ + H+
Thymine + FMN-N5-peroxide <=> Methylureidoacrylate + FMN-N5-oxide
5,10-Methylenetetrahydrofolate + tRNA containing uridine at position 54 + NADH + H+ <=> Tetrahydrofolate + tRNA containing ribothymidine at position 54 + NAD+
Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-D-glucose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose
Chenodeoxycholate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cholic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
UDP-2-acetamido-2,6-dideoxy-beta-L-mannose <=> UDP-2-acetamido-2,6-dideoxy-beta-L-glucose
UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose <=> UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-galactose
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NADP+
UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + D-Alanine <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose + H2O
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose + H2O <=> 2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + UDP
Ephedrine + NAD+ <=> (S)-2-(Methylamino)-1-phenylpropan-1-one + NADH + H+
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + Acetyl-CoA <=> UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idose + CoA
5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + CTP <=> CMP-5-N-acetyl-7-N-(D-alanyl)-legionaminic acid + Diphosphate
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idose <=> UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-gulose
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-gulose + H2O <=> 2,4-Diacetamido-2,4,6-trideoxy-beta-L-gulose + UDP
2,4-Diacetamido-2,4,6-trideoxy-beta-L-gulose + Phosphoenolpyruvate + H2O <=> 5,7-Diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid + Orthophosphate
Feruloyl-CoA + H2O <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA
2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> 5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + Orthophosphate
CTP + 5,7-Diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid <=> CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid + Diphosphate
[Sulfatase]-L-serine + S-Adenosyl-L-methionine <=> [Sulfatase]-3-oxo-L-alanine + 5'-Deoxyadenosine + L-Methionine
Thioredoxin + ROOH <=> Thioredoxin disulfide + H2O + ROH
Glutaredoxin + ROOH <=> Glutaredoxin disulfide + H2O + ROH
ATP + L-Arginine <=> Diphosphate + (L-Arginyl)adenylate
L-Arginine + Peptidyl-carrier protein + ATP <=> L-Arginyl-[pcp] + AMP + Diphosphate
(L-Arginyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Arginyl-[pcp]
ATP + 3,4-Dihydroxybenzoate + Aryl-carrier protein <=> AMP + Diphosphate + 3,4-Dihydroxybenzoyl-[aryl-carrier protein]
ATP + 3,4-Dihydroxybenzoate <=> Diphosphate + (3,4-Dihydroxybenzoyl)adenylate
(3,4-Dihydroxybenzoyl)adenylate + Aryl-carrier protein <=> AMP + 3,4-Dihydroxybenzoyl-[aryl-carrier protein]
2 Glutathione + ROOH <=> Glutathione disulfide + H2O + ROH
NADH + ROOH + H+ <=> NAD+ + H2O + ROH
Selenophosphoric acid + Geranyl diphosphate + tRNA containing 5-[(methylamino)methyl]-2-thiouridylate + H2O <=> 5-Methylaminomethyl-2-selenouridine34 in tRNA + (2E)-3,7-Dimethylocta-2,6-diene-1-thiol + Diphosphate + Orthophosphate
Geranyl diphosphate + tRNA containing 5-[(methylamino)methyl]-2-thiouridylate <=> 5-Methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA + Diphosphate
Selenophosphoric acid + 5-Methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA <=> 5-Methylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA + (2E)-3,7-Dimethylocta-2,6-diene-1-thiol
5-Methylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA + H2O <=> 5-Methylaminomethyl-2-selenouridine34 in tRNA + Orthophosphate
UDP-N-acetyl-beta-L-fucosamine <=> UDP-2,6-dideoxy-2-acetamidino-beta-L-galactose
(2R)-2-Hydroxy fatty acid + Oxygen <=> Fatty acid + H2O + CO2
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate <=> UDP-2,3-dideoxy-2-acetamido-3-acetamidino-alpha-D-mannuronic acid
NADPH + H2O <=> NADH + Orthophosphate
S-Inosyl-L-homocysteine + H2O <=> Inosine + L-Homocysteine
XTP + H2O <=> XDP + Orthophosphate
UDP-N-acetyl-D-galactosaminuronic acid + ATP + L-Glutamine + H2O <=> UDP-2-acetamido-2-deoxy-alpha-D-galacturonamide + AMP + L-Glutamate + Diphosphate
(S)-Limonene + H2O + Acceptor <=> (-)-Perillyl alcohol + Reduced acceptor
(R)-Limonene + H2O + Acceptor <=> (+)-Perillyl alcohol + Reduced acceptor
1-Alkyl-sn-glycerol + Tetrahydropteridine + Oxygen <=> 1-Hydroxyalkyl-sn-glycerol + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
ADP + D-Glucosamine <=> AMP + D-Glucosamine 6-phosphate
8-Oxo-GDP + H2O <=> 8-Oxo-GMP + Orthophosphate
Spermidine + Citrate + ATP <=> N-Citryl-spermidine + AMP + Diphosphate
N-Citryl-spermidine + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine + Aryl-carrier protein
N-Citryl-spermidine + Spermidine + ATP <=> N8,N'8-Citryl-bis(spermidine) + AMP + Diphosphate
N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine + Spermidine + ATP <=> N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + AMP + Diphosphate
N8,N'8-Citryl-bis(spermidine) + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + Aryl-carrier protein
N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> Petrobactin + Aryl-carrier protein
[Protein]-N6-[(R)-dihydrolipoyl]-L-lysine + ROOH <=> Protein N6-(lipoyl)lysine + H2O + ROH
Enzyme N6-(dihydrolipoyl)lysine + ROOH <=> Enzyme N6-(lipoyl)lysine + H2O + ROH
UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-mannose + NADP+
Protoporphyrinogen IX + 3 Acceptor <=> Protoporphyrin + 3 Reduced acceptor
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate <=> UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + 2-Oxoglutarate
GDP-glucose + D-Mannose 1-phosphate <=> D-Glucose 1-phosphate + GDP-mannose
GTP + Dephospho-CoA <=> GDP + CoA
3-Oxoisoapionate <=> L-Erythrulose + CO2
3-Oxoisoapionate 4-phosphate <=> Erythrulose 1-phosphate + CO2
L-Tyrosine + Hydrogen peroxide <=> 3,4-Dihydroxy-L-phenylalanine + H2O
5-Deoxy-D-ribulose 1-phosphate <=> Glycerone phosphate + Acetaldehyde
S-Methyl-5-thio-D-ribulose 1-phosphate <=> Glycerone phosphate + (2-Methylthio)acetaldehyde
[(1R)-1-Hydroxy-2-(trimethylamino)ethyl]phosphonate + Oxygen <=> Betaine + Orthophosphate
[2-(Trimethylamino)ethyl]phosphonate + 2-Oxoglutarate + Oxygen <=> [(1R)-1-Hydroxy-2-(trimethylamino)ethyl]phosphonate + Succinate + CO2
ATP + 3-Oxoisoapionate <=> ADP + 3-Oxoisoapionate 4-phosphate
3,5,6-Trichloropyridin-2-ol + FADH2 + Oxygen <=> 3,6-Dichloropyridine-2,5-dione + Cl- + FAD + H2O
3,6-Dichloropyridine-2,5-diol + FADH2 + Oxygen <=> 6-Chloro-3-hydroxypyridine-2,5-dione + Cl- + FAD + H2O
6-Chloropyridine-2,3,5-triol + FADH2 + Oxygen <=> 3,6-Dihydroxypyridine-2,5-dione + Cl- + FAD + H2O
trans-2,3-Dehydroacyl-CoA + NADP+ <=> (2E,4Z)-2,4-Dienoyl-CoA + NADPH + H+
5'-Deoxyadenosine + H2O <=> 5-Deoxy-D-ribose + Adenine
4-Hydroxy-3-methoxy-benzaldehyde + L-Alanine <=> Vanillylamine + Pyruvate
Methylureidoacrylate + H2O <=> Methylaminoacrylate + CO2 + Ammonia
Methylureidoacrylate + H2O <=> Methylaminoacrylate + Carbamate
Ureidoacrylate + H2O <=> Aminoacrylate + CO2 + Ammonia
(6E)-8-Methylnon-6-enoyl-CoA + Vanillylamine <=> Capsaicin + CoA
2,6-Dichlorohydroquinone + FADH2 + Oxygen <=> 2-Chloro-6-hydroxy-1,4-benzoquinone + FAD + Cl- + H2O
8-Methyl-6-nonenoic acid <=> (6E)-8-Methylnon-6-enoyl-CoA
(3E)-3-Enoyl-CoA + NADP+ <=> (2E,4E)-2,4-Dienoyl-CoA + NADPH + H+
(3E)-3-Enoyl-CoA + NADP+ <=> (2E,4Z)-2,4-Dienoyl-CoA + NADPH + H+
Thiocyanate + 2 Ferricytochrome c + H2O <=> Cyanate + Sulfur + 2 Ferrocytochrome c + H+
S-Adenosyl-L-methionine + 3,3'-Di-O-methyl-4alpha-mannobiose <=> S-Adenosyl-L-homocysteine + 1,3,3'-Tri-O-methyl-4alpha-mannobiose
ADP + Polyphosphate <=> AMP + Polyphosphate
1,2-beta-D-Glucan + H2O <=> Sophorose + 1,2-beta-D-Glucan
N4-Acetylcytidine + H2O <=> Cytidine + Acetate
CMP-N-acetylneuraminate + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R <=> CMP + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-R
UDP-D-xylose + G03532 <=> UDP + G10913
Neryl diphosphate + Isopentenyl diphosphate <=> Diphosphate + (2Z,6Z)-Farnesyl diphosphate
(2Z,6Z)-Farnesyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Nerylneryl diphosphate
ATP + Salicylate <=> (Salicyl)adenylate + Diphosphate
(Salicyl)adenylate + CoA <=> AMP + 2-Hydroxybenzoyl-CoA
ATP + Salicylate + CoA <=> AMP + Diphosphate + 2-Hydroxybenzoyl-CoA
D-Xylose + NADP+ <=> D-Xylono-1,4-lactone + NADPH + H+
7,8-Dihydrobiopterin + NADP+ <=> Biopterin + NADPH + H+
Protein-L-arginine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3R)-3-hydroxy-L-arginine + Succinate + CO2
Phosphoenolpyruvate + GTP <=> Enolpyruvoyl-2-diphospho-5'-guanosine + Diphosphate
3-Phospho-D-glycerate + GTP <=> 3-(D-Glyceryl)-diphospho-5'-guanosine + Diphosphate
Enolpyruvoyl-2-diphospho-5'-guanosine + 7,8-Didemethyl-8-hydroxy-5-deazariboflavin <=> GMP + Dehydro coenzyme F420-0
3-(D-Glyceryl)-diphospho-5'-guanosine + 7,8-Didemethyl-8-hydroxy-5-deazariboflavin <=> GMP + 3PG-factor 420-0
L-Isoleucine + 2-Oxoglutarate + Oxygen <=> 3(1)-Hydroxy-L-isoleucine + Succinate + CO2
3(1)-Hydroxy-L-isoleucine + 2-Oxoglutarate + Oxygen <=> (4S)-31,4-Dihydroxy-L-isoleucine + Succinate + CO2
Abieta-8,11,13-triene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Ferruginol + [Oxidized NADPH---hemoprotein reductase] + H2O
(+)-Pinoresinol + 2 Oxidized azurin + H2O <=> (+)-6-Hydroxypinoresinol + 2 Reduced azurin + 2 H+
S-Adenosyl-L-methionine + 3-Demethylubiquinol <=> S-Adenosyl-L-homocysteine + Ubiquinol
2-Polyprenyl-6-methoxyphenol + Oxygen <=> 2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + H2O
Tryptamine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Serotonin + [Oxidized NADPH---hemoprotein reductase] + H2O
3 Malonyl-CoA + 5 Methylmalonyl-CoA + 7 NADPH + 7 H+ <=> Protomycinolide IV + 8 CoA + 8 CO2 + 4 H2O + 7 NADP+
1-Phospho-alpha-D-galacturonate + H2O <=> D-Galacturonate + Orthophosphate
3-Sulfanylpropanoate + Oxygen <=> 3-Sulfinopropanoate
L-Glutamate + 2-Oxoglutarate + Oxygen <=> (3R)-3-Hydroxy-L-glutamate + Succinate + CO2
beta-D-Mannose <=> beta-D-Glucose
D-Apiose <=> Apulose
S-Adenosyl-L-methionine + (2R)-2-Hydroxy-4-(methylsulfanyl)butanoate <=> S-Adenosyl-L-homocysteine + (2R)-4-(Dimethylsulfaniumyl)-2-hydroxybutanoate
S-Adenosyl-L-methionine + 2-Heptyl-4-hydroxyquinoline-N-oxide <=> S-Adenosyl-L-homocysteine + 2-Heptyl-1-methoxyquinolin-4(1H)-one
Apulose 4-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Xylulose 5-phosphate + Glycerone phosphate
Halima-5(6),13-dien-15-yl diphosphate + Adenosine <=> 1-Tuberculosinyladenosine + Diphosphate
D-Apionolactone + H2O <=> D-Apionate
Chitobiose + H2O <=> beta-D-Glucosaminyl-(1->4)-N-acetyl-D-glucosamine + Acetate
Neryl diphosphate + H2O <=> Nerol + Diphosphate
N,N-Dimethyl-N'-phenylurea compound + Reduced ferredoxin + Oxygen + H+ <=> N-Methyl-N'-phenylurea compound + Oxidized ferredoxin + Formaldehyde + H2O
alpha-N-Dichloroacetyl-p-aminophenylserinol + Reduced acceptor + 2 Oxygen <=> Chloramphenicol + Acceptor + 2 H2O
4-Aminobenzoate + Reduced acceptor + 2 Oxygen <=> 4-Nitrobenzoate + Acceptor + 2 H2O
2-Methylthio-N6-dimethylallyladenine in tRNA + Reduced acceptor + Oxygen <=> N6-[(2E)-4-Hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenine in tRNA + Acceptor + H2O
Cholest-4-en-3-one + Acceptor + H2O <=> 25-Hydroxycholest-4-en-3-one + Reduced acceptor
3-Oxo-Delta1-steroid + Acceptor + H2O <=> Steroid 1,3-dione + Reduced acceptor
3-Oxo-Delta1-steroid + H2O <=> 1-Hydroxy-3-oxo-steroid
1-Hydroxy-3-oxo-steroid + Acceptor <=> Steroid 1,3-dione + Reduced acceptor
Heme I + Acceptor + H2O <=> Hydroxyheme I + Reduced acceptor
Hydroxyheme I <=> Heme A + H2O
3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + Oxygen + H2O <=> 5-[(4-Hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + Ammonia + Hydrogen peroxide
3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + Oxygen <=> 5-[(4-Hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + Hydrogen peroxide
5-[(4-Hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O <=> 5-[(4-Hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + Ammonia
L-Kynurenine + 2-Oxoglutarate <=> 4-Hydroxy-2-quinolinecarboxylic acid + L-Glutamate + H2O
Mercaptopyruvate + [Protein]-L-cysteine <=> Pyruvate + [Protein]-S-sulfanyl-L-cysteine
[Protein]-S-sulfanyl-L-cysteine + Thioredoxin <=> Hydrogen sulfide + [Protein]-L-cysteine + Thioredoxin disulfide
[Glycine cleavage system H]-N6-octanoyl-L-lysine <=> Dihydrolipoylprotein
L-Kynurenine + Glyoxylate <=> 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O
3-Hydroxy-L-kynurenine + Glyoxylate <=> Xanthurenic acid + Glycine + H2O
3-Hydroxy-L-kynurenine + Glyoxylate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + Glycine
ATP + D-Ribulose <=> ADP + D-Ribulose 1-phosphate
D-Ribulose 1-phosphate <=> Glycerone phosphate + Glycolaldehyde
12,18-Didecarboxysiroheme <=> Dihydro-heme d1
Dihydro-heme d1 + Acceptor <=> Heme d1 + Reduced acceptor
sn-Glycerol 1-phosphate + all-trans-Heptaprenyl diphosphate <=> Heptaprenylglyceryl phosphate + Diphosphate
Heptaprenylglyceryl phosphate + H2O <=> Heptaprenylglycerol + Orthophosphate
Heptaprenylglycerol + 2 Acetyl-CoA <=> Diacetylheptaprenylglycerol + 2 CoA
Phosphatidylethanolamine + G13044 <=> 1,2-Diacyl-sn-glycerol + G13152
Allantoate + Orthophosphate <=> (S)-Ureidoglycine + Carbamoyl phosphate
CMP-N-acetylneuraminate + T antigen <=> CMP + G10794
UDP-N-acetyl-D-glucosamine + T antigen <=> UDP + G13153
Nopaline + H2O + Acceptor <=> L-Arginine + 2-Oxoglutarate + Reduced acceptor
Octopine + H2O + Acceptor <=> L-Arginine + Pyruvate + Reduced acceptor
Dihydroisopentenyldehydrorhodopin + Acceptor <=> Isopentenyldehydrorhodopin + Reduced acceptor
Dihydrobisanhydrobacterioruberin + Acceptor <=> Bisanhydrobacterioruberin + Reduced acceptor
Bacterioruberin <=> Bisanhydrobacterioruberin + 2 H2O
Bacterioruberin <=> Monoanhydrobacterioruberin + H2O
Monoanhydrobacterioruberin <=> Bisanhydrobacterioruberin + H2O
Levoglucosan + NAD+ <=> 3-Dehydrolevoglucosan + NADH + H+
Ultra-long-chain fatty acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Ultra-long-chain omega-hydroxy fatty acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Decanoyl-[acp] + 4 Reduced ferredoxin + 2 Oxygen + 4 H+ <=> Dec-9-ynoyl-[acyl-carrier protein] + 4 Reduced ferredoxin + 4 H2O
Decanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Dec-9-enoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O
Dec-9-enoyl-[acyl-carrier protein] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Dec-9-ynoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O
S-Methyl-5-thio-D-ribulose 1-phosphate <=> S-Methyl-1-thio-D-xylulose 5-phosphate
S-Methyl-5-thio-D-ribulose 1-phosphate <=> S-methyl-1-thio-D-ribulose 5-phosphate
Coenzyme F420-0 + FMN <=> Dehydro coenzyme F420-0 + Reduced FMN
ATP + Glycine <=> Diphosphate + Glycyl-AMP
Glycyl-AMP + Peptidyl-carrier protein <=> AMP + Glycyl-[peptidyl-carrier protein]
ATP + Glycine + Peptidyl-carrier protein <=> AMP + Diphosphate + Glycyl-[peptidyl-carrier protein]
C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-L-tyrosine + S-Adenosyl-L-methionine <=> C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + CO2 + 5'-Deoxyadenosine + L-Methionine
ATP + L-Alanine <=> Diphosphate + (L-Alanyl)adenylate
(L-Alanyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Alanyl-[peptidyl-carrier protein]
ATP + L-Alanine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Alanyl-[peptidyl-carrier protein]
ATP + L-Glutamate <=> Diphosphate + (L-Glutamyl)adenylate
(L-Glutamyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Glutamyl-[peptidyl-carrier protein]
ATP + L-Glutamate + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Glutamyl-[peptidyl-carrier protein]
6-Deoxy-6-sulfo-D-fructose + D-Glyceraldehyde 3-phosphate <=> (2S)-3-Sulfolactaldehyde + beta-D-Fructose 6-phosphate
3-Methylbutanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 5-Methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2
2-Methylpropanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 4-Methyl-3-oxopentanoyl-[acyl-carrier-protein] + CoA + CO2
(S)-2-Methylbutanoyl-CoA + Malonyl-[acyl-carrier protein] <=> (4S)-4-Methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2
Lauroyl-CoA + Malonyl-[acyl-carrier protein] <=> 3-Oxotetradecanoyl-[acp] + CoA + CO2
p-Coumaroyl-CoA + 5-Hydroxyanthranilate <=> Avenanthramide A + CoA
Caffeoyl-CoA + 5-Hydroxyanthranilate <=> Avenanthramide C + CoA
Acetyl-CoA + G13154 <=> CoA + G13155
dTDP-L-rhamnose + Alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol <=> dTDP + G13156
GDP-D-mannose + G13156 <=> GDP + G13158
GDP-D-mannose + Alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol <=> GDP + G13159
GDP-D-mannose + G13159 <=> GDP + G13160
dTDP-L-rhamnose + G13160 <=> dTDP + G13154
CDP-abequose + G13155 <=> CDP + G13161
GDP-D-mannose + G13156 <=> GDP + G13162
ATP + Levoglucosan + H2O <=> ADP + D-Glucose 6-phosphate
GTP + Polyphosphate <=> GDP + Polyphosphate
4-O-Methyl-D-glucopyranuronate ester + H2O <=> 4-O-Methyl-D-glucuronic acid + Alcohol
Cyclic 2,3-bisphospho-D-glycerate + H2O <=> 2,3-Bisphosphoglycerate
C-terminal [Mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + 5'-Deoxyadenosine + L-Methionine + Acceptor <=> C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + S-Adenosyl-L-methionine + Reduced acceptor
S-Methyl-1-thio-D-xylulose 5-phosphate + Reduced acceptor <=> Methanethiol + 1-Deoxy-D-xylulose 5-phosphate + Acceptor
1'-Hydroxy-gamma-carotene <=> 1'-Hydroxy-1',2'-dihydro-beta,psi-caroten-4'-one
1'-Hydroxy-1',2'-dihydro-beta,psi-caroten-4'-one + S-Adenosyl-L-methionine <=> Thiothece-474 + S-Adenosyl-L-homocysteine
CO2 + Hydrogen <=> Formate
ATP + 1,6-Anhydro-N-acetyl-beta-muramate + H2O <=> ADP + N-Acetylmuramic acid 6-phosphate
Reduced FMN + Oxygen <=> FMN-N5-peroxide
L-Serine <=> Ethanolamine + CO2
L-Tryptophan <=> Indole + Dehydroalanine
L-Tyrosine <=> Phenol + Dehydroalanine
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NAD+
L-Lyxonate <=> 2-Dehydro-3-deoxy-L-arabinonate + H2O
(2S)-2,3-Dihydroxypropane-1-sulfonate <=> 3-Oxopropane-1-sulfonate + H2O
2-Hydroxyethanesulfonate <=> Acetaldehyde + Sulfite
(2S)-2,3-Dihydroxypropane-1-sulfonate <=> Hydroxyacetone + Sulfite
ATP + L-Cysteine <=> Diphosphate + (L-Cysteinyl)adenylate
(L-Cysteinyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Cysteinyl-protein
ATP + L-Cysteine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Cysteinyl-protein
Aceneuramate <=> N-Acetyl-D-mannosamine + Pyruvate
N-Acetyl-alpha-neuraminate <=> Aceneuramate
Aceneuramate <=> N-Acetyl-beta-neuraminate
Fatty acid + Oxygen <=> (2R)-2-Hydroperoxyfatty acid
ATP + L-Threonine <=> Diphosphate + (L-Threonyl)adenylate
(L-Threonyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Threonyl-[L-threonyl-carrier protein]
ATP + L-Threonine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Threonyl-[L-threonyl-carrier protein]
(9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 2(R)-HPOT
(2,3-Dihydroxybenzoyl)adenylate + Aryl-carrier protein <=> AMP + 2,3-Dihydroxybenzoyl-[aryl-carrier protein]
ATP + 2,3-Dihydroxybenzoate + Aryl-carrier protein <=> AMP + Diphosphate + 2,3-Dihydroxybenzoyl-[aryl-carrier protein]
Alkyl sulfate + 2-Oxoglutarate + Oxygen <=> Aldehyde + Succinate + CO2 + Sulfate
ATP + L-Serine <=> Diphosphate + (L-Seryl)adenylate
(L-Seryl)adenylate + Peptidyl-carrier protein <=> AMP + L-Seryl-[peptidyl-carrier protein]
ATP + L-Serine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Seryl-[peptidyl-carrier protein]
ATP + L-Tryptophan <=> Diphosphate + (L-Tryptophyl)adenylate
(L-Tryptophyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Tryptophyl-[peptidyl-carrier protein]
ATP + L-Tryptophan + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Tryptophyl-[peptidyl-carrier protein]
D-Glyceraldehyde 3-phosphate + Arsenate ion + NAD+ <=> 1-Arsono-3-phospho-D-glycerate + NADH
ATP + dGMP + L-Aspartate <=> ADP + Orthophosphate + N6-Succino-2-amino-2'-deoxyadenylate
Betaine + Co(I) corrinoid protein <=> N,N-Dimethylglycine + Methyl-Co(III) corrinoid protein
2 S-Adenosyl-L-methionine + Protein-L-arginine + Reduced acceptor <=> S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + Protein-(5S)-C-methyl-L-arginine + Acceptor
ATP + 3-Amino-5-hydroxybenzoate + Acyl-carrier protein <=> 3-Amino-5-hydroxybenzoyl-[acyl-carrier protein] + AMP + Diphosphate
10-Formyltetrahydrofolate + GDP-4-amino-4,6-dideoxy-alpha-D-mannose <=> Tetrahydrofolate + GDP-N-formyl-alpha-D-perosamine
(3R)-3-Hydroxyacyl-CoA + Poly[(R)-3-hydroxyalkanoate]n(n) <=> CoA + Poly[(R)-3-hydroxyalkanoate]n(n+1)
ATP + Apulose <=> ADP + Apulose 4-phosphate
ATP + Fatty acid <=> ADP + Acyl phosphate
3'-Phosphoadenylyl sulfate + omega-Hydroxy-beta-dihydromenaquinone-9 <=> Adenosine 3',5'-bisphosphate + omega-Sulfo-beta-dihydromenaquinone-9
1-Phosphatidyl-D-myo-inositol + H2O <=> 2-Acyl-sn-glycero-3-phospho-1D-myo-inositol + Fatty acid
Phosphatidate + H2O <=> 2-Acyl-sn-glycerol 3-phosphate + Fatty acid
Alkyl sulfate + H2O <=> Alcohol + Sulfate
2-Butyloctyl sulfate + H2O <=> 2-Butyloctan-1-ol + Sulfate
2-Hydroxy-3-methyl-fatty-acyl-CoA <=> 2-Methyl-branched fatty aldehyde + Formyl-CoA
(2R)-2-Hydroxy-long-chain fatty acyl-CoA <=> Long-chain fatty aldehyde + Formyl-CoA
C-terminal [Mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + H2O <=> C-terminal [Mycofactocin precursor peptide]-glycine + 3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one
3-Oxoisoapionate 4-phosphate + H2O <=> Glycolate + 3-Phospho-D-glycerate
(3R)-3-Hydroxyacyl-[acyl-carrier protein] + UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine <=> UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + Acyl-carrier protein
(Salicyl)adenylate + Peptidyl-carrier protein <=> AMP + Salicyl-[peptidyl-carrier protein]
ATP + Salicylate + Peptidyl-carrier protein <=> AMP + Diphosphate + Salicyl-[peptidyl-carrier protein]
ATP + D-Arabinose <=> ADP + alpha-D-Arabinopyranose 1-phosphate
GTP + alpha-D-Arabinopyranose 1-phosphate <=> Diphosphate + GDP-D-arabinopyranose